mbre_31958
Species: M.brevicollis
Alias: mbre_31958
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-II
Family: CDC25
Subfamily: CDC25
Protein domain

Protein domains of mbre_31958.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Rhodanese mbre_31958.AA RHOD 382-497 19 5.3e-12 47.11 SMART 1-94 (94) Show / Hide
Range on Protein: 382-497
Range on HMM: 1-94/94
Sequence Identity: 19% (23 aa)

SRLLKGEYAEHFTHVLVLDCRFSFEYDGGHILNAQRAWLREHVLNHLFYNPQVPFTETHRTAVVFHCEFSAQRGPDQYEFARCLDDIFSHGTGQRLWPNM
. ..... ...   ....|||   ||.|||| .|    . | .              .... |...| .|  |.  . . |. |  .  .        |.
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR---------LGIDKDKPVIVYC-RSGNRS--APRAAWWLREAGYK--------NV

FILEKGYREFYKNYPE
.||. |..|.....|.
YILDGGWKEWKRACPP

Phosphatase mbre_31958.AA Family.CDC25.PD 383-496 37 7.6e-41 126.7 In-house 2-116 (117) Show / Hide
Range on Protein: 383-496
Range on HMM: 2-116/117
Sequence Identity: 37% (43 aa)

RLLKGEYAEHFTHVLVLDCRFSFEYDGGHILNAQRAWLREHVLNHLFYNPQVPFTETHRTAVVFHCEFSAQRGPDQYEFARCLDDIFSHGTGQRL-WPNM
.|||||..|..... ..|||...||.|||| .|.... ||.. .... .|.|...|..|| |.||||||..|||..... |..|. ... . ..| .|..
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

FILEKGYREFYKNYP
..||.||.||.....
ylLegGykeffeeve

Phosphatase mbre_31958.AA Group.Cx5R-II.PD 383-496 37 7.6e-41 126.7 In-house 2-116 (117) Show / Hide
Range on Protein: 383-496
Range on HMM: 2-116/117
Sequence Identity: 37% (43 aa)

RLLKGEYAEHFTHVLVLDCRFSFEYDGGHILNAQRAWLREHVLNHLFYNPQVPFTETHRTAVVFHCEFSAQRGPDQYEFARCLDDIFSHGTGQRL-WPNM
.|||||..|..... ..|||...||.|||| .|.... ||.. .... .|.|...|..|| |.||||||..|||..... |..|. ... . ..| .|..
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

FILEKGYREFYKNYP
..||.||.||.....
ylLegGykeffeeve

Phosphatase mbre_31958.AA Subfamily.CDC25.PD 383-496 37 7.6e-41 126.7 In-house 2-116 (117) Show / Hide
Range on Protein: 383-496
Range on HMM: 2-116/117
Sequence Identity: 37% (43 aa)

RLLKGEYAEHFTHVLVLDCRFSFEYDGGHILNAQRAWLREHVLNHLFYNPQVPFTETHRTAVVFHCEFSAQRGPDQYEFARCLDDIFSHGTGQRL-WPNM
.|||||..|..... ..|||...||.|||| .|.... ||.. .... .|.|...|..|| |.||||||..|||..... |..|. ... ...| .|...
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

FILEKGYREFYKNYP
.||.||.||..... 
ylLegGykeffeeve

Phosphatase mbre_31958.AA Rhodanese 385-494 15 2.3e-09 31.37 Pfam 1-102 (102) Show / Hide
Range on Protein: 385-494
Range on HMM: 1-102/102
Sequence Identity: 15% (19 aa)

LKGEYAEHF--THVLVLDCRFSFEYDGGHILNAQRAWLREHVLNHL--FYNPQVPFTETHRTAVVFHCEFSAQRGPDQYEFARC-----LDDIFSHGTGQ
.  ...|.    .....|.|   ||..||| .|    .    |  .  . .  . . . ..  .|..|      | .   ...|     |   . .    
TPEWLKEMMNDPDYVIIDVRPPEEYEKGHIPGA-HVNIPW--LEEEHDLEELGIKLDKDKPI-IVVYC-----HGNRSG-AWACLVWWMLKA-MGYP---

RLWPNMFILEKGYREFYKN
   || ..|. |. .... 
---PNVYVLDGGWEAWKAE

Sequence
Name Sequence Type Origin Length Description Download
mbre_31958.AA Protein None 580 None Fasta, JSON
mbre_31958.NA RNA None 1740 None Fasta, JSON
mbre_31958.AA.PD_382-497 Protein Phosphatase Domain None 116 None Fasta, JSON