mbre_31992
Species: M.brevicollis
Alias: mbre_31992
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-II
Family: CDC25
Subfamily: CDC25
Protein domain

Protein domains of mbre_31992.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Rhodanese mbre_31992.AA RHOD 220-331 25 6.8e-18 66.69 SMART 1-94 (94) Show / Hide
Range on Protein: 220-331
Range on HMM: 1-94/94
Sequence Identity: 25% (29 aa)

IDTVWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLSQTLILVHCEFSKERG-PALYHYLKRVEAKACKNGGQGSLFPHLYVL
. . |.. . . .|..|||.|.||||.|||. ||.|. ...  ..     |    . . |.| .| .|. | .. .|..   |            . |.|
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR----LGIDKDKPVIVYC-RSGNRSAPRAAWWLREAGYK------------NVYIL

HQGYKQFHAEHPT
. |.| . ...| 
DGGWKEWKRACPP

Phosphatase mbre_31992.AA Family.CDC25.PD 223-330 40 4.8e-38 117.6 In-house 4-116 (117) Show / Hide
Range on Protein: 223-330
Range on HMM: 4-116/117
Sequence Identity: 40% (45 aa)

VWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS-----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYV
..|. ......|||||.||||||.|||. ||||.|  ....|..|.. . .     .|....|||||.||||.|...|..|.....|.  ..|.||.|..
lkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypelyl

LHQGYKQFHAEHP
|||.|..|..   
LegGykeffeeve

Phosphatase mbre_31992.AA Group.Cx5R-II.PD 223-330 40 4.8e-38 117.6 In-house 4-116 (117) Show / Hide
Range on Protein: 223-330
Range on HMM: 4-116/117
Sequence Identity: 40% (45 aa)

VWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS-----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYV
..|. ......|||||.||||||.|||. ||||.|  ....|..|.. . .     .|....|||||.||||.|...|..|.....|.  ..|.||.|..
lkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypelyl

LHQGYKQFHAEHP
|||.|..|..   
LegGykeffeeve

Phosphatase mbre_31992.AA Subfamily.CDC25.PD 223-330 40 4.8e-38 117.6 In-house 4-116 (117) Show / Hide
Range on Protein: 223-330
Range on HMM: 4-116/117
Sequence Identity: 40% (45 aa)

VWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS-----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYV
..|. ......|||||.||||||.|||. ||||.|  ....|..|.. . .     .|....|||||.||||.|...|..|.....|.  ..|.||.|..
lkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypelyl

LHQGYKQFHAEHP
|||.|..|..   
LegGykeffeeve

Rhodanese mbre_31992.AA Rhodanese 221-328 26 6.4e-13 42.64 Pfam 1-102 (102) Show / Hide
Range on Protein: 221-328
Range on HMM: 1-102/102
Sequence Identity: 26% (32 aa)

DTVWGDGRRKFRDYIIIDARYPYEYDGGHLIGA-VNFYLPDMAAEY--LLARGD--LSQTLI-LVHCEFSKERGPALYHY-----LKRVEAKACKNGGQG
.  | . . .  ||.|||.| |.||..||. || ||. .    .|   |  .|      . | .|.|  .  |.   ..      ||.   .        
TPEWLKEMMNDPDYVIIDVRPPEEYEKGHIPGAHVNIPW---LEEEHDLEELGIKLDKDKPIIVVYC--HGNRSG-AWACLVWWMLKAMGYP--------

SLFPHLYVLHQGYKQFHAE
   |  |||  |.....||
---PNVYVLDGGWEAWKAE

Sequence
Name Sequence Type Origin Length Description Download
mbre_31992.AA Protein None 387 None Fasta, JSON
mbre_31992.NA RNA None 1161 None Fasta, JSON
mbre_31992.AA.PD_220-331 Protein Phosphatase Domain None 112 None Fasta, JSON