mbre_24379
Species: M.brevicollis
Alias: mbre_24379
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: FCP1
Protein domain

Protein domains of mbre_24379.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase mbre_24379.AA Subfamily.FCP1.PD 65-212 50 4.3e-60 191.4 In-house 1-149 (150) Show / Hide
Range on Protein: 65-212
Range on HMM: 1-149/150
Sequence Identity: 50% (75 aa)

RKLILILDLDKTLIHSTIDSIAsHWLREGVYDIFHFDL--GKHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNRFFSTRILTQDE
|||.|..|||.||||.|.|... .. .| . || .|.|   |..||.|.||.|..|||.|...||.||||||.|.|||.| .|.||....||.|||..||
rklvLvvDlDqtlihttkdpti-evkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrde

SFSIENKAKNLDALLPGGDSMAVILDDLPAVWDFQTNVVPALPYEFFKHV
... ..|.|.|..|.| |||| ||.||  .||.|..|..   ||.|||.|
llnassktkklkklfptgdsmvviiDDredvWnfaenlikvkpykfFkgv

Phosphatase mbre_24379.AA CPDc 65-213 31 7.6e-42 146.26 SMART 1-173 (173) Show / Hide
Range on Protein: 65-213
Range on HMM: 1-173/173
Sequence Identity: 31% (54 aa)

RKLILILDLDKTLIHS-----------TIDSIASHWLREGVYD---------IFHFDLGKHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILR
.|..|.|||| ||.||           ...| . .  |. ..          |...|   | .|.| ||..| ||. .. .||||..||| |.||. .|.
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD

IIDPSNRFFSTRILTQDESFSIENK--AKNLDALLPG-GDSMAVILDDLPAVWDFQT-NVVPALPYEFFKHVE
..|| ...|..|.|. |.... . |   |..  |..   .|| .|.|| |..|...  | .|  |. .|.|  
MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT

Phosphatase mbre_24379.AA Family.FCP.PD 65-207 29 1.2e-37 118.4 In-house 1-139 (164) Show / Hide
Range on Protein: 65-207
Range on HMM: 1-139/164
Sequence Identity: 29% (43 aa)

RKLILILDLDKTLIHSTIDSIASHWLREgvydIFHFDLGKHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNRFFSTRILTQDESF
.|..|.||||.||.||...  ... .       ...|  ..|.|.|.||.|. ||| ....||..|.|.. |.||.....|.||....|..|.| ..  .
kkklLVlDLdetLvhselkpknkpdfvv----kveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrllrdecvl

SIENKAKNLDALlPGGDSMAVILDDLPAVWDFQT-NVVPALPYE
  .|. |.|..| . ..|. .|.|| |... ... |...  ...
vkgnyvkdLskl-grdlskviiiDdspdsyklnpdnaikvksfk

Phosphatase mbre_24379.AA NIF 67-197 26 4.5e-29 107.42 Pfam 1-141 (189) Show / Hide
Range on Protein: 67-197
Range on HMM: 1-141/189
Sequence Identity: 26% (39 aa)

LILILDLDKTLIHSTIDSIASHW-LREGVYDIFHFDLG----KHTYYTKV-RPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPS-NRFF-STRIL
..|.|||| ||.|..      .|  .. ..| | ....    .|..|... ||... ||. .  |||..|.|.. ..||. ....|||  ...| ....|
KTLVLDLDETLVHCN------PWWEPPNWHD-FIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRL

---TQDESF-SIEN--K-A-KNLDALLPGG-D-SMAVILDDLPAVWDFQ
   . ...    ..  .   |.|. |...  | |  .|.|. | .| .|
ICWYREHCWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQ

Phosphatase mbre_24379.AA Group.HAD.PD 67-211 23 1e-25 80.0 In-house 2-152 (190) Show / Hide
Range on Protein: 67-211
Range on HMM: 2-152/190
Sequence Identity: 23% (38 aa)

LILILDLDKTLI-HSTIDSIASHWLREGVYDIFHFDLGKHTYYTKVR------------PGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNRFF
|.||||..|. |.. . ..... . .|   .  .  |. .| . |            |.|..||| ....||....|.| |.||.......|. ...|| 
dtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdeaf

STRILTQDESFSIENKAK----NLDALLPGGDSM-AVILDDLPAVWDFQTnvvpalpyeffkH
|.|... ..  ...|.    | |  ... | .  ||.|. |.|. |..            .  
syrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafec------------n

Phosphatase mbre_24379.AA Subfamily.DULLARD.PD 66-196 26 2.7e-17 51.9 In-house 2-136 (172) Show / Hide
Range on Protein: 66-196
Range on HMM: 2-136/172
Sequence Identity: 26% (35 aa)

KLILILDLDKTLIHSTIDSIASHWLREGVYDIFHFDLGKHT----YYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNRFFSTRILTQD
. .|.||||.|||||..|| . . ..||.   |.. .  ..    .|   || .  ||. .  .|.. |.| . ..||. ..  .| .... |   |. .
rktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyrqh

ESFSIENKAKNLDALLPGGDSMaVILDDLPAVWD-F
 . ..  |.| .. .  .|. .|||. |  .  .  
Ctlesgkytkdlslvsedlssv-iilDnspvayrkn

Phosphatase mbre_24379.AA Subfamily.HSPC129.PD 67-199 26 4.3e-17 51.3 In-house 3-131 (164) Show / Hide
Range on Protein: 67-199
Range on HMM: 3-131/164
Sequence Identity: 26% (35 aa)

LILILDLDKTLIHSTIDSIASHWLREGVydifHFDLGKHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNRFFSTRILTQDESFSI
|.||||.||.|...  . .  |   |    ...  ... | ..|| |. ||| .   .|. ..|  .. ||...| ..||.....|.  .      .|  
fslvldldetlvhcslakledatlsfkv----eyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrlfrehcvcvd

ENKAKNLDALlPGGDSMAVILDDLPAVWDFQT-N
|.|. |     | ..|.|. |  . .|  |    
gnyikdlsil-Grdlsktiivdnspqafayqlen

Phosphatase mbre_24379.AA Subfamily.SCP.PD 66-202 28 1.2e-16 49.7 In-house 2-133 (163) Show / Hide
Range on Protein: 66-202
Range on HMM: 2-133/163
Sequence Identity: 28% (39 aa)

KLILILDLDKTLIHSTIDSIASHWLregVYDIfHFDLGKHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNrFFSTRILTQDESFS
|  |.||||.||.||..  . .  .   |  . ..|  .|  | . || .. ||. .   .|. ..|    .||.... ..|..| ....|..   |   
kkclvldldetlvhssfkpvenadf---vvpv-eidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkkn-vikarlfrescvfh

IENKAKNLDALlpG-GDSMAVILDDLPAVWDFQTN-VVP
|  |.|  |  |   .  ||.|. || . |...  ||  
kgnyvkdlsrl--Grdlkkvvivdnspasyifhpdnavp

Phosphatase mbre_24379.AA Subfamily.TIM50.PD 104-178 26 7.7e-10 28.0 In-house 21-94 (150) Show / Hide
Range on Protein: 104-178
Range on HMM: 21-94/150
Sequence Identity: 26% (19 aa)

KHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPsNRFFSTRILTQDESFSIENKAKNLDALLP
|. . .| |||..|||| | ...|. ..|  .  .| ...  .|| . . . |.. .  ..   .. |.|. |  
ktGwrfkkrPgvdafleelaelfeivvftseqgltaaplidkldP-kqlimyrlfrdatkyvdGehvkdlsklnr

Sequence
Name Sequence Type Origin Length Description Download
mbre_24379.AA Protein None 858 None Fasta, JSON
mbre_24379.NA RNA None 2574 None Fasta, JSON
mbre_24379.AA.PD_65-213 Protein Phosphatase Domain None 149 None Fasta, JSON