Gene mbre_34461
mbre_34461
Species: M.brevicollis
Alias: mbre_34461
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_34461.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | mbre_34461.AA | CPDc | 122-265 | 42 | 2.5e-71 | 244.17 | SMART | 1-173 (173) | Show / Hide |
Range on Protein: 122-265 Range on HMM: 1-173/173 Sequence Identity: 42% (73 aa) GRKCLVLDLDETLVHS--------------SFKPVPNADFILP----------IEIDGTTHNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSD ..|.||||||.||||| |||. ..||| | .||||..| .||.|||.|.|||. .|..|...||... .||.|| | KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD RLDPQG-FIQHR-LFRQHCVFHENS-YIKD-LSRLGR-NVDQCIIVDNAPSSYLFHPQNAVPIESWFDNPEDT .||| . .. .| |.|.|||.|. |.|| ||...| . ||.|. |.|...||.||.||..||....|| MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT |
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| Phosphatase | mbre_34461.AA | Subfamily.SCP.PD | 123-284 | 66 | 3.1e-87 | 279.4 | In-house | 2-163 (163) | Show / Hide |
Range on Protein: 123-284 Range on HMM: 2-163/163 Sequence Identity: 66% (108 aa) RKCLVLDLDETLVHSSFKPVPNADFILPIEIDGTTHNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDPQGFIQHRLFRQHCVFHENSYI .|||||||||||||||||||.||||..|.|||||.|.|||||||||||||...|.||||||||||| |||.||.| ||....|..||||..||||...|. kkclvldldetlvhssfkpvenadfvvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkknvikarlfrescvfhkgnyv KDLSRLGRNVDQCIIVDNAPSSYLFHPQNAVPIESWFDNPEDTALRDLIPFFTRLAELNNIY ||||||||......||||.|.||.|||.||||.|||||..||| |.||.|....|.. .... kdlsrlGrdlkkvvivdnspasyifhpdnavpveswfddeedtelldllplleelskvedvl |
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| Phosphatase | mbre_34461.AA | NIF | 124-284 | 40 | 2.2e-78 | 271.49 | Pfam | 1-189 (189) | Show / Hide |
Range on Protein: 124-284 Range on HMM: 1-189/189 Sequence Identity: 40% (76 aa) KCLVLDLDETLVHSS--FKPVPNADFILPIEIDGTTHNVYVLK-RPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDP--QGFI--QHRL---FRQH |.|||||||||||.. ..|... |||.|| ..| .|..|| | ||..||||. |..|.|..|||...|| || |..|| .... .||| .|.| KTLVLDLDETLVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWYREH CV-FHEN-SY-I-KDLSRL--GR-NVDQCIIVDNAPSSYLFHPQNAVPIES-WFD-----N-PED--TALRDLIPFF-TRLA-EL-NNIY |. . .. .| . ||||.| .| . .. |||||.| |. ..|.|..||.. |.. . | | ..| ||.||. || . .. CWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLALQCLDDVR |
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| Phosphatase | mbre_34461.AA | Family.FCP.PD | 123-283 | 49 | 3.6e-63 | 201.5 | In-house | 2-163 (164) | Show / Hide |
Range on Protein: 123-283 Range on HMM: 2-163/164 Sequence Identity: 49% (80 aa) RKCLVLDLDETLVHSSFKPVPNADFILPIEIDGTTHNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDP-QGFIQHRLFRQHCVFHENSY .|.||||||||||||..||....||....|||.....|||.|||..||||| ..|.|.|.|||| |||.|| | ||| ......||.|..||.....| kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrllrdecvlvkgny IKDLSRLGRNVDQCIIVDNAPSSYLFHPQNAVPIESWFDNPEDTALRDLIPFFTRLAELNNI .||||.|||. ...||.|. |.|| ..|.||....|....|.||.| ||.||...||. ... vkdLsklgrdlskviiiDdspdsyklnpdnaikvksfkedpkDteLldLlpfleslakeedv |
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| Phosphatase | mbre_34461.AA | Subfamily.HSPC129.PD | 123-282 | 49 | 8.8e-56 | 177.3 | In-house | 2-162 (164) | Show / Hide |
Range on Protein: 123-282 Range on HMM: 2-162/164 Sequence Identity: 49% (79 aa) RKCLVLDLDETLVHSSFKPVPNADFILPIEIDGTTHNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDPQ-GFIQHRLFRQHCVFHENSY . .|||||||||||.|......| . ...| . .|..||| |||. |||| |||||.||||| || . | |||. ...|||||.||| ...| efslvldldetlvhcslakledatlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrlfrehcvcvdgny IKDLSRLGRNVDQCIIVDNAPSSYLFHPQNAVPIESWFDNPEDTALRDLIPFFTRLAELNN ||||| |||.... |||||.| .. . .| .||||||.. .|. | .|.||. .|||... ikdlsilGrdlsktiivdnspqafayqlenGipieswfadendsellkllpfleklaeked |
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| Phosphatase | mbre_34461.AA | Subfamily.DULLARD.PD | 123-277 | 43 | 4.2e-51 | 162.1 | In-house | 2-165 (172) | Show / Hide |
Range on Protein: 123-277 Range on HMM: 2-165/172 Sequence Identity: 43% (72 aa) RKCLVLDLDETLVHS--------SFKPVPNADFILPIEIDGTTHNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDP-QGFIQHRLFRQH || |||||||||.|| . |.. . ||.| . |. . ..|| |||.||.||. | ...|.||||. .||..| |.|| .| ...|..||| rktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyrqh CVFHENSYIKDLSRLGRNVDQCIIVDNAPSSYLFHPQNAVPIESWFDNPEDTALRDLIPFFTRL |. ....|.|||| . .... ||.||.|..| .|.||.||.||. .|.|||| .|.||. | CtlesgkytkdlslvsedlssviilDnspvayrknpdnaipikswisdpsdtallnllPfldal |
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| Phosphatase | mbre_34461.AA | Group.HAD.PD | 123-280 | 31 | 5.9e-46 | 146.1 | In-house | 1-184 (190) | Show / Hide |
Range on Protein: 123-280 Range on HMM: 1-184/190 Sequence Identity: 31% (58 aa) RKCLVLDLDETLV-HSSFKPVPNADFILPIEIDGTT----HNVYVLKR------------PFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDP-QGF ...||||||..|. |.|..| .... . .|. |. ...|.||| |..|||||. |.|.|.|.|||.. .||.|| . .|..... kdtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdea IQHRLFRQHCVFHENSYIK------DLSRLGRNVDQCIIVDNAPSSYLF--HPQNAVPIESWFDNPEDTALRDLIPFFTRLAEL .|..|..||.. . . . ||. |.|.. . .|.|| ||.. | .|.||..|....|...|..| .|||....... fsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdfiddildaellglipdlenidvr |
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| Phosphatase | mbre_34461.AA | Subfamily.TIM50.PD | 158-279 | 37 | 1.7e-34 | 108.2 | In-house | 22-143 (150) | Show / Hide |
Range on Protein: 158-279 Range on HMM: 22-143/150 Sequence Identity: 37% (46 aa) HNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDPQGFIQHRLFRQHCVFHENSYIKDLSRLGRNVDQCIIVDNAPSSYLFHPQNAVPIES . . |||.|| |||. ..|||.|.||.. .|.|. |.|||...|..||||... . . . .|||| | |.... |.|| ..|. ..|.||. .. tGwrfkkrPgvdafleelaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkesvklqpenalalkk WFDNPEDTALRDLIPFFTRLAE | |..|. | ||..|.. .|. wkGnaddrelldllaflktiat |
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| Phosphatase | mbre_34461.AA | Subfamily.FCP1.PD | 125-245 | 27 | 1.4e-15 | 47.0 | In-house | 4-131 (150) | Show / Hide |
Range on Protein: 125-245 Range on HMM: 4-131/150 Sequence Identity: 27% (35 aa) CLVLDLDETLVHSSFKPV---P--NADFILPIEIDGTTHNVYVLKRPFVDEFLEATGKLFEVVLFTASLPKYASPVSDRLDPQG-FIQHRLFRQHCVFHE .||.|||.||.|.. .| . . | ... . .. || .|| . |||| ||.|. ..| . .||. . |||.. . ..|.. .....| vLvvDlDqtlihttkdptievkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrdellna NSYIKDLSRLGRNVDQ-CIIVDNAPSSY .|.|..| . |. .|.|. . ssktkklkklfptgdsmvviiDDredvW |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_34461.AA | Protein | None | 290 | None | Fasta, JSON |
| mbre_34461.NA | RNA | None | 870 | None | Fasta, JSON |
| mbre_34461.AA.PD_122-284 | Protein Phosphatase Domain | None | 163 | None | Fasta, JSON |