• Phosphatome.Net

Gene mbre_25683

mbre_25683
Species: M.brevicollis
Alias: mbre_25683
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: TIM50
Protein domain

Protein domains of mbre_25683.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase mbre_25683.AA CPDc 130-260 30 1.7e-33 118.54 SMART 1-173 (173) Show / Hide 
Range on Protein: 130-260
Range on HMM: 1-173/173
Sequence Identity: 30% (54 aa)

TDYTIVLDLEDTLLHS-----------------EWTFE----------------------HGWRTKKRPFLANFLESCVMELGLELVVFSESQVAEAMLL
  .|.|||| .||.||                 ||| .                      |.|..||||.. .||. |  ..  |..||. ..   |  .
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCS-KW-YEMHVFTMGMRMYADPV

IDKMDPKQ-CIQYR-LYKPHMRYVDGE-PVKD-LDWLNR-DLSKVIVIDDKPEQVRKHKDNVLRVRPFKGTPEQA
.|. |||.  . || ||. |..|..|   ||| |. .|| |||.||.||| |.  ..|..| . ..|... ..  
LDMLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT
Phosphatase mbre_25683.AA Subfamily.TIM50.PD 131-284 53 2.6e-66 211.4 In-house 2-150 (150) Show / Hide 
Range on Protein: 131-284
Range on HMM: 2-150/150
Sequence Identity: 53% (82 aa)

DYTIVLDLEDTLLHSEWTFEHGWRTKKRPFLANFLESCVmELgLELVVFSESQVAEAMLLIDKMDPKQCIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKV
.||.||.|.|.|.|.|||...|||.||||....|||... || .|.|||...|...|. ||||.||||.|.|||......|||||.||||..||||||||
pytlvlelkdvlvhpewtyktGwrfkkrPgvdafleela-el-feivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskv

IVIDDKPEQVRKHKDNVLRVRPFKGTPeqaNDRELLDVLTFLANIVQSRVPDVR
||.| ..|.|.....|.|.....||..   .||||||.|.||..|..|.| |||
ivvdldkesvklqpenalalkkwkGna---ddrelldllaflktiatsevedvr
Phosphatase mbre_25683.AA NIF 132-284 30 3.6e-42 151.23 Pfam 1-189 (189) Show / Hide 
Range on Protein: 132-284
Range on HMM: 1-189/189
Sequence Identity: 30% (60 aa)

YTIVLDLEDTLLHSE--WTFE---------------HGWRTKK-RPFLANFLESCVMELGLELVVFSESQVAEAMLLIDKMDP--KQCI--QYRL---YK
.|.|||| .||.|..  |. .               |.|...| ||..  ||...  ..  |.|... |.   |  .||. ||  |...  ..||   | 
KTLVLDLDETLVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHM-SKY-YEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWYR

PHMR-YVDG-EP-V-KDLDWL--NR-DLSKVIVIDDKPEQVRKHKDNVLRVRP-FKGTPEQAND------RELLDVLTFL-ANIVQSRV-PDVR
 |.. |..|    | |||. |  || |||.|| .|. |.    ..|| . . | ..|.  . .|      .|||| | ||   .. ... .|||
EHCWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYH-DDDDSPDDFWNELLDLLPFLIEYLA-LQCLDDVR
Phosphatase mbre_25683.AA Family.FCP.PD 131-283 38 1.8e-40 127.8 In-house 2-163 (164) Show / Hide 
Range on Protein: 131-283
Range on HMM: 2-163/164
Sequence Identity: 38% (65 aa)

DYTIVLDLEDTLLHSEWT---------------FEHGWRTKKRPFLANFLESCVmELgLELVVFSESQVAEAMLLIDKMDP-KQCIQYRLYKPHMRYVDG
...||||..||.|||..                |. ...||||.| .|||..  ||  |.|.|. |. . |. ..|..|| |.....||.. ....|.|.
kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvs-el-yeiviftastrkyadpvadiLDpekklfkkrllrdecvlvkg

EPVKDLDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPFKGTPeqaNDRELLDVLTFLANIVQSrvPDV
 ||||..|.|||||||.|||.|.... ..||...|..||..|   .|.||||.|.|| .. ..   || 
nyvkdLsklgrdlskviiiDdspdsyklnpdnaikvksfkedp---kDteLldLlpfleslake--edv
Phosphatase mbre_25683.AA Group.HAD.PD 132-284 26 6.5e-27 84.0 In-house 2-190 (190) Show / Hide 
Range on Protein: 132-284
Range on HMM: 2-190/190
Sequence Identity: 26% (52 aa)

YTIVLDLEDTLL-HSEWTFEHGWRTKKR-------------------------------PFLANFLESCvMELgLELVVFSESQVAEAMLLIDKMDP-KQ
.|.|||| ..|  |....  .|.| |..                               |.|..|||..  ||  |||||...... |  .....|....
dtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflerv-gel-yelvvftagtreyadpvvgavdvgde

CIQYRLYKPHMRYVDGEPVK------DLDWLNRDLSKVIVIDDKPEQVRK--HKDNVLRVRPFkgTpEQANDRELLDVLTFLANIVQSRVPDVR
. ||... . .|..|. ..      ||..|.|||.||..||.||  .    ...|.| . .|    .  .| |||. . .| ||..... ||. 
afsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdf--i-ddildaellglipdlenidvrfgkdvg
Phosphatase mbre_25683.AA Subfamily.SCP.PD 155-277 33 1.4e-22 69.2 In-house 41-158 (163) Show / Hide 
Range on Protein: 155-277
Range on HMM: 41-158/163
Sequence Identity: 33% (41 aa)

TKKRPFLANFLEScvMELGLELVVFSESQVAEAMLLIDKMDPKQCIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPFk
.||||. .||.   .    |.|.|. |.   |  ..| .|.|. |..||.. .  ...|  ||||  | |||.||...|. |.    |.||. |. .   
vlkrpfvdeflkk--vgelfevvlftaslakyadpvadlldkknvikarlfrescvfhkgnyvkdlsrlGrdlkkvvivdnspasyifhpdnavpvesw-

gtPEQANDRELLDVLTFLANIVQ
 .. .|.||||.| .| .. .  
--fddeedtelldllplleelsk
Phosphatase mbre_25683.AA Subfamily.HSPC129.PD 155-283 36 5.9e-22 67.3 In-house 41-163 (164) Show / Hide 
Range on Protein: 155-283
Range on HMM: 41-163/164
Sequence Identity: 36% (44 aa)

TKKRPFLANFLEScvMELGLELVVFSESQVAEAMLLIDKMDPK-QCIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPF
. |||| .|||   .    |...|. |.   |  |.| .||. . ...||.. |   |||. .|||. | ||||| |..|..|.| . .  .    .. |
vrlrpflrefler--vsklfevilftaskkvyadklldlldpekklvrhrlfrehcvcvdgnyikdlsilGrdlsktiivdnspqafayqlenGipiesw

kgtPEQANDRELLDVLTFLANIVQSrvPDV
|.|||..|.|| ....    ||        
---fadendsellkllpfleklaek--edv
Phosphatase mbre_25683.AA Subfamily.DULLARD.PD 155-275 32 2.5e-19 58.7 In-house 49-165 (172) Show / Hide 
Range on Protein: 155-275
Range on HMM: 49-165/172
Sequence Identity: 32% (39 aa)

TKKRPFLANFLEScVMElGLELVVFSESQVAEAMLLIDKMDP-KQCIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPF
|||..  ||.  | .   .||.|  |    |. ..||.|  .. .. |.|. | .  .|. .|||  .. |||.||..|. |.. ||. || .... .  
vykrPhvdlfldv-vsk-WydlviftasmeeyaaavvdkldsgrgilkrryyrqhCtlesgkytkdlslvsedlssviilDnspvayrknpdnaipiksw

KGTPeqaNDRELLDVLTFLANI
 |   .| .||..| ||  .  
isdp---sdtallnllPfldal
Phosphatase mbre_25683.AA Subfamily.FCP1.PD 152-254 26 1.3e-07 21.2 In-house 43-144 (150) Show / Hide 
Range on Protein: 152-254
Range on HMM: 43-144/150
Sequence Identity: 26% (27 aa)

GWRTKKRPFLANFLESCVMELGLELVVFSESQVAEAMLLIdkMDPKQCI-QYRLYKPHMRYVDGEPVKDLDW-LNRDLSKVIVIDDKpEQVRKHKDNVLR
. .|.|| |..|||.      | .. ... . ||..  |  .||.. . . |.          . .|.|.  .... | |..|||. |.|....|...|.
vyyvklRpnlkeFleklsklyelhiytmgtraYaeqiaki--lDpekklFserilsrdellnassktkklkklfptgdsmvviiDDr-edvWnfaenlik

VRPFK
|.|  
vkpyk
Sequence
Name Sequence Type Origin Length Description Download
mbre_25683.AA Protein None 336 None Fasta, JSON
mbre_25683.NA RNA None 1008 None Fasta, JSON
mbre_25683.AA.PD_130-284 Protein Phosphatase Domain None 155 None Fasta, JSON