Gene MONBRDRAFT_13731
MONBRDRAFT_13731
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of MONBRDRAFT_13731.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | MONBRDRAFT_13731.AA | Hydrolase | 3-213 | 19 | 8.3e-18 | 62.42 | Pfam | 1-167 (167) | Show / Hide |
Range on Protein: 3-213
Range on HMM: 1-167/167
Sequence Identity: 19% (42 aa)
TKAVFVDISGTLLVG-NAALPGAIDALARLKQNYTVRLVTNTSKESQRAIYERLTTLGFAVEPSEVFTSLAATRALLLRDQRRCFFIIPPATEEDFADVP
.|||. |. |||. | .. |....||.. ....|... |. . ..... .||. ..
IKAVVFDKDGTLTDGSEHPHAQAWVEAAREYGY------------WPFEEVEYIWGRGI-G--DRIIDWWRATDEHI-----------------------
RDSPDTVVLGLAPDSFDYATLDTGFQILRQPDARLIAIN-TSRFYATPSGVHIAAGAFVRALEYAANVSAHVVGKPSAEFFRAAAASCHLDVESC--VMI
| ..||.. | | .| |.. ... | ..| | . . | ... .. ...... | .||||..| ...|. . .... | .|.
----D-EYLGVIADDQPYPGAREALQALKRMGIKVAMITNDNR-NAQAVLEHLGIA-YFDHIIDSDDVG--IVGKPHPEMYEKACQRLGVKPHECGCMMV
GDDTGDDFEGAMRAG
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GDGINDDPMLAQ-AG
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| Phosphatase | MONBRDRAFT_13731.AA | Subfamily.LHPP.PD | 4-213 | 49 | 4e-91 | 292.4 | In-house | 2-213 (213) | Show / Hide |
Range on Protein: 4-213 Range on HMM: 2-213/213 Sequence Identity: 49% (105 aa) KAVFVDISGTLLVGNAALPGAIDALARLKQN-YTVRLVTNTSKESQRAIYERLTTLGFAVEPSEVFTSLAATRALLLRDQRRCFFIIPPATEEDFADVPR |.|..|.||.| | .||.||...||.||||. ..||.||||.|||.|...|||..|||.|| .||||||.|.|.|| ....|.|... ....|||... . kgvllDlsGvlyveeaaipgsveAlkrLkqsglkvrfvtnttkeskrelverLqrlgfkveeeevftslpaarqllkkeklrpfllveddaredFegidt DSPDTVVLGLAPDSFDYATLDTGFQILRQPDAR-LIAINTSRFYATPSGVHIAAGAFVRALEYAANVSAHVVGKPSAEFFRAAAASCHLDVESCVMIGDD |||..||.||||.||.|.||...|..|.. ... ||||.....|.. .|.....||||.|||||..|.|.||||||..||..|.....|.|..||||||. dspnavviglapesfnyetlnkafrlllekkkkvLiaigkgkyykrkdglaldvGafvkaLeyatdveaevvGkPsklfFesalqelgvdpeeavmiGDD TGDDFEGAMRAG ||..||...| vkdDvgGAqkvG |
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| Phosphatase | MONBRDRAFT_13731.AA | Family.NagD.PD | 4-213 | 31 | 2.3e-61 | 195.7 | In-house | 2-239 (239) | Show / Hide |
Range on Protein: 4-213 Range on HMM: 2-239/239 Sequence Identity: 31% (75 aa) KAVFVDISGTLLVGNAALPGAIDALARLKQN-YTVRLVTNTSKESQRAIYERLTTLGFAVEPSEVFTSLAATRALLLRDQRRCF-----FIIPPATEEDF ..|..|..|.| |..|.|||..|| ||.|. .|..|||.|..|.......|..||| |. .|.|.|.||....| ......| .|. ....|.. dtvlfDcdGVLwlgekaipgavealnrLrqkgkkvlfvTNnstksreellkklqklgfkvseeeifssaaaaadylkkrkkkpfkkkvyligeeglkeel AD----------------------VPRDSPDTVVLGLAPDSFDYATLDTGFQILRQPDARLIAINTSRFYATPSGVHIAAGAFVRALEYAANVSAHVVGK .. | ......|.. |...|.|..| . |..|..||...||.|. .....|..... ||.||.|||.|....|.|||| eelgieslgtgpdkledeldgdlevdlekdvgaVvvgadehfsyeklakAfryLqnpdvlfiatnedktlkepevlipgaGsfvaaletatgrealvvGK PSAEFFRAAAASCHLDVESCVMIGDDTGDDFEGAMRAG ||. .|.|. .....| |..|||||.. .| ..|...| PskllfealleklgvdpertvmiGDrlntDilfaqkcG |
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| Phosphatase | MONBRDRAFT_13731.AA | Group.HAD.PD | 4-222 | 24 | 2.4e-25 | 77.9 | In-house | 2-182 (190) | Show / Hide |
Range on Protein: 4-222 Range on HMM: 2-182/190 Sequence Identity: 24% (53 aa) KAVFVDISGTLLvgnaaLPGAIDALARLKQNYTVRL-VTNTSKESQRAIYERLTTLGFAVEPSEvftslAATRALLLRDQRRCFFIIPPATEEDFadvpr . ...|..|.| |.|. ..|. |... |.. .||....|. ...||. ||| || .| .... | |.. .. ....|... ...|. dtlvlDldgvlw-----lhgspepleglrskgkvlifltnnatksrlyllkrlallgflveeve-----phldeflervgelyelvvftagtrey----- DSPDTVVLGLAPDSFDYATLDTGFQILRQPDARLIAINTsrfyatpsgvhiAAGAFVRALEyaaNvSAHVVGKPSAEFFRAaaaschlDVESCVMIGDDT .... . |.| | ...|..|.| |.| |. ||.||.|| . ... .|||. .|.. . | ..||||. || . adpvvgavdvgdeafsyrklrdacvylkgpgalllatnr------------dlgalvrdle---k-vviidnkpsvfafec-------npenalmigdfi gDDFEGAMRAGLRAMLVATG .|.. ||. .| ... -ddildaellglipdlenid |
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| Phosphatase | MONBRDRAFT_13731.AA | Subfamily.PGP.PD | 104-213 | 28 | 1.3e-17 | 52.2 | In-house | 134-243 (243) | Show / Hide |
Range on Protein: 104-213 Range on HMM: 134-243/243 Sequence Identity: 28% (32 aa) SPDTVVLGLApDSFDYATLDTGFQILRQPDARLIAINTSRFYATPSGVHIA-AGAFVRALEYAANVSAHVVGKPSAEFFRAAAASCHLDVESCVMIGDDT .. .|| |. |.|. | ..|..||. ..| |. . . . ..| |. .|..|.|.| |.. .. ||||||. . | . ..| | ..|.|| . dvgaVvvgfd-ehfsyvklakAlnylqnpdvlfvatneDetlplnpevvipgtGslvaavetasgreplvvGKPskllldallekakidpertlmvGDrl GDDFEGAMRAG | . . ..| dtDilfgkncG |
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| Phosphatase | MONBRDRAFT_13731.AA | Subfamily.PGP.PD | 5-81 | 32 | 7.8e-13 | 36.6 | In-house | 3-80 (243) | Show / Hide |
Range on Protein: 5-81 Range on HMM: 3-80/243 Sequence Identity: 32% (25 aa) AVFVDISGTLLVGNAALPGAIDALARLK-QNYTVRLVTNTSKESQRAIYERLTTLGFAVEP-SEVFTSLAATrALLLRD | .| |.| |..|.|||...| .|. .. .| .||| | .. .. .... ||| | .|...| |.. | .|.. tvlfDcdGVlWlgetaipgavevlnaLraagKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavl-adylkq |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MONBRDRAFT_13731.AA | Protein | None | 229 | None | Fasta, JSON |
| MONBRDRAFT_13731.NA | RNA | None | 687 | None | Fasta, JSON |
| MONBRDRAFT_13731.AA.PD_3-213 | Protein Phosphatase Domain | None | 211 | None | Fasta, JSON |