Gene mbre_21060
mbre_21060
Species: M.brevicollis
Alias: mbre_21060
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_21060.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | mbre_21060.AA | Hydrolase | 14-257 | 12 | 8e-06 | 21.48 | Pfam | 1-167 (167) | Show / Hide |
Range on Protein: 14-257 Range on HMM: 1-167/167 Sequence Identity: 12% (31 aa) TKLFVFDCDGVIWRGATLIDGVADALDGLRRHGKRVAFITNNSTKTRANFVKKFHGLGLTWVERDDVWSSASAAAAYLTQRAKLDKSRKVYVVGQSGLCE .|..|||.||....| .. . .|. . .|. . ....|.. |. . ..... ..... IKAVVFDKDGTLTDG--------------------------SEHPHAQAWVEAAREYGY----------WPFEEVEYIWGRGI-G----DRIIDWWRATD ELCEAGYTVLGGPDDEGSSVFPVPERFEVDPAVGAVVVGFDRAINYYKLAY-ATMCARENKDCLFLAT--NRDAITHLNDEQEFPGGGTMVAALETAIGR |. . .. . . | | | ... ....| ||.| .| .| . ....... .. EHI-----------------------------D-EYLGVIAD-DQPYPGAREALQALKRMGIKVAMITNDNRNAQAVLE----HLGIA-YFDHIIDSDDV APEVAGKPSPFLVDALYAFHGLDRD--SAHAVMVGDRLDTDIIFGNTNN . ..|||.| . .. |... ..||||.. .|. . . G--IVGKPHPEMYEKACQRLGVKPHECG--CMMVGDGINDDPMLAQ-AG |
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| Phosphatase | mbre_21060.AA | Subfamily.PGP.PD | 15-256 | 46 | 5.3e-89 | 286.0 | In-house | 2-242 (243) | Show / Hide |
Range on Protein: 15-256 Range on HMM: 2-242/243 Sequence Identity: 46% (114 aa) KLFVFDCDGVIWRGATLIDGVADALDGLRRHGKRVAFITNNSTKTRANFVKKFHGLGLTWVERDDVWSSASAAAAYLTQRAKLDKSRKVYVVGQSGLCEE . ..||||||.|.|.|.|.|....|. ||..||.|.|.||||||||....|||. ||..........|||...|.||.|.. ...|||..|..||.|| dtvlfDcdGVlWlgetaipgavevlnaLraagKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavladylkqakakkekkkvyligeeglkee LCEAGYTVLG-GPDDEGSSVFPV-PERFEVDPAVGAVVVGFDRAINYYKLAYATMCAReNKDCLFLATNRDAITHLNDEQEFPGGGTMVAALETAIGRAP |.|.|...|| |||.. .. |.......|||||||||....|.|||.|... . |.|.||.|||.|....||.|. .|| |..|||.|||.||.| leelgieslgvgpdkledeldgdlaekvklekdvgaVvvgfdehfsyvklakAlnylq-npdvlfvatneDetlplnpevvipgtGslvaavetasgrep EVAGKPSPFLVDALYAFHglDRDSAHAVMVGDRLDTDIIFGNTN |.||||..|.|||. . ..|.....|||||||||| ||... lvvGKPskllldalleka--kidpertlmvGDrldtDilfgknc |
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| Phosphatase | mbre_21060.AA | Family.NagD.PD | 15-256 | 44 | 2.2e-82 | 264.5 | In-house | 2-238 (239) | Show / Hide |
Range on Protein: 15-256 Range on HMM: 2-238/239 Sequence Identity: 44% (108 aa) KLFVFDCDGVIWRGATLIDGVADALDGLRRHGKRVAFITNNSTKTRANFVKKFHGLGLTWvERDDVWSSASAAAAYLTQRAKLDKSRKVYVVGQSGLCEE . ..||||||.|.|.. |.|...||. ||..||.| |.||||||.|....||.. ||... ......|||.|||.||..|.| ....|||..|..||.|| dtvlfDcdGVLwlgekaipgavealnrLrqkgkkvlfvTNnstksreellkklqklgfkv-seeeifssaaaaadylkkrkkkpfkkkvyligeeglkee LCEAGYTVLG-GPDDEGSSVFPVPeRFEVDPAVGAVVVGFDRAINYYKLAYATMCAReNKDCLFLATNRDAIThLNDEQEFPGGGTMVAALETAIGRAPE |.|.|...|| |||.. .. .......|||||||.|....| ||| |... . |.|.||.|||.|... ..|. .|| |..|||||||.|| .. leelgieslgtgpdkledeldgdl-evdlekdvgaVvvgadehfsyeklakAfryLq-npdvlfiatnedktl-kepevlipgaGsfvaaletatgreal VAGKPSPFLVDALYAFHglDRDSAHAVMVGDRLDTDIIFGNTN |.||||..|..||.. . ..|....||.||||.|||.|.... vvGKPskllfeallekl--gvdpertvmiGDrlntDilfaqkc |
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| Phosphatase | mbre_21060.AA | Group.HAD.PD | 15-256 | 25 | 5.9e-39 | 122.3 | In-house | 2-186 (190) | Show / Hide |
Range on Protein: 15-256 Range on HMM: 2-186/190 Sequence Identity: 25% (62 aa) KLFVFDCDGVIWrgatlIDGVADALDGLRRHGKRVAFITNnstktranfvkkfhglgltwverddvwsSASAAAAYLTQRAKLDKSRKVYVVgqsglcEE ...|.|.|||.| ..|....|.|||..||. .|.|| .|. ..||..|..|..... .|. |.| dtlvlDldgvlw-----lhgspepleglrskgkvlifltn----------------------------natksrlyllkrlallgflveeve------ph LCE----AgytvlgGPDdEGSSVFPVPERFEVDPAVGAVVVGfDRAINYYKLAYATMCAREnKDCLFLATNRdaithlndeqefpGGGTMVAALE--TAI . |.. .. ||. .| .|| ||||.|| |.|..| ||. |... .. ...|.||||| . | .|..|| ..|. | |. ldeflerv------gel-yelvvftagtreyadpvvgavdvg-deafsyrklrdacvylkg-pgalllatnr-------------dlgalvrdlekvvii GRAPEVAG---KPSPFLVDALYafhgLdRDSAHAVMVGDRLDTDIIFGNTN . .|.. |. . . |. .|...|...|...|. ... dnkpsvfafecnpenalmigdf----i-ddildaellglipdlenidvrfg |
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| Phosphatase | mbre_21060.AA | Subfamily.LHPP.PD | 17-94 | 29 | 2.7e-14 | 41.3 | In-house | 4-80 (213) | Show / Hide |
Range on Protein: 17-94 Range on HMM: 4-80/213 Sequence Identity: 29% (23 aa) FVFDCDGVIWRGATLIDGVADALDGLRRHGKRVAFITNNSTKTRANFVKKFHGLGLTwVERDDVWSSASAAAAYLTQR .. | ||.. . | | ..||. |...| .| |.||.. ..... |.. . ||. ||...| .|..||...|... vllDlsGvlyveeaaipgsveAlkrLkqsglkvrfvtnttkeskrelverLqrlgfk-veeeevftslpaarqllkke |
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| Phosphatase | mbre_21060.AA | Subfamily.LHPP.PD | 148-250 | 31 | 3.1e-10 | 28.0 | In-house | 106-206 (213) | Show / Hide |
Range on Protein: 148-250 Range on HMM: 106-206/213 Sequence Identity: 31% (33 aa) AVVVGF-DRAINYYKLAYATMCARENKDCLFLATNRDAITHLNDEQeFPGGGTMVAALETAIGRAPEVAGKPSPFLVDAlyAFHGLDRDSAHAVMVGDRL |||.| . . || .| | .|.|. . .| .. . .|. . |. |.||| |.. || ||||.. . | . |. | ..|||.|| . avviglapesfnyetlnkafrlllekkkkvLiaigkgkyykrkdgl-aldvGafvkaLeyatdveaevvGkPsklfFes--alqelgvdpeeavmiGDDv DTDI |. kdDv |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_21060.AA | Protein | None | 301 | None | Fasta, JSON |
| mbre_21060.NA | RNA | None | 903 | None | Fasta, JSON |
| mbre_21060.AA.PD_14-257 | Protein Phosphatase Domain | None | 244 | None | Fasta, JSON |