Mbre_s22
Species: M.brevicollis
Alias: Mbre_s22
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: NagD
Subfamily: PGP
Protein domain

Protein domains of Mbre_s22.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Mbre_s22.AA Family.NagD.PD 21-253 25 2.1e-25 77.6 In-house 1-239 (239) Show / Hide
Range on Protein: 21-253
Range on HMM: 1-239/239
Sequence Identity: 25% (62 aa)

YDVFVLDQYGVIHNGSAPYPHAVEVVQRLRQAGKTVTILSNSSKPAHF-AHARLIEWGFG-EVATIVTGGEMVRQGMRNRWSDFAaYGSKYTLMGWDVET
.| ...|  ||...|....|.|||...||||.||.|....|.|. .    . .| . ||. .   |..   .... ...|  .       | ........
idtvlfDcdGVLwlgekaipgavealnrLrqkgkkvlfvTNnstksreellkklqklgfkvseeeifssaaaaadylkkrkkkpf-kkkvyligeeglke

DVLA-DLDQYDQAPIDEADFILLQGinVLSTGSEP-A---PIEEVAHWQPHLKAAR---ARNLPIVCANPDKVVvrpDGSQGLCPGT---VAAMYEALGG
 . ........| ...| .  .    ... ..  |    ..|  ...   ||.|    ..   .  | ||..     ...|.||.|||.  | | . ..|
eleelgieslgtgpdkledeldgdl--evdlekdvgaVvvgadehfsyeklakAfryLqnpdvlfiatnedktl---kepevlipgaGsfvaaletatgr

QVHYVGKPHALVYDKTLEQLaGVPKSRIVAVGDSLHHDIEGALKAG
|||..|.....||.| || ..|.| .||.|..||..| |.|     
ealvvGKPskllfeallekl-gvdpertvmiGDrlntDilfaqkcG

Phosphatase Mbre_s22.AA Subfamily.PGP.PD 21-97 26 1e-15 45.6 In-house 1-80 (243) Show / Hide
Range on Protein: 21-97
Range on HMM: 1-80/243
Sequence Identity: 26% (21 aa)

YDVFVLDQYGVIHNGSAPYPHAVEVVQRLRQAGKTVTILSNSSKPAHFA-HARLIEWGFGEVA--TIVTGGEMVRQGMRN
.| ...|..||...|....|.||||...||.|||.|....|.|  .  .   .. . ||. .    |.. . .. . ...
fdtvlfDcdGVlWlgetaipgavevlnaLraagKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavladylkq

Phosphatase Mbre_s22.AA Subfamily.PGP.PD 176-253 33 8.1e-12 32.8 In-house 166-243 (243) Show / Hide
Range on Protein: 176-253
Range on HMM: 166-243/243
Sequence Identity: 33% (27 aa)

VCANPDKVVVrpDGSQGLCPGT---VAAMYEALGGQVHYVGKPHALVYDKTLEQLaGVPKSRIVAVGDSLHHDIEGALKAG
| .| |...     ..   |||   |||.  | | .  .||||..|..|..||.  .. ..|.. |||.|..||. . ..|
vatneDetlp--lnpevvipgtGslvaavetasgreplvvGKPskllldalleka-kidpertlmvGDrldtDilfgkncG

Phosphatase Mbre_s22.AA Subfamily.LHPP.PD 195-253 35 5.9e-10 26.7 In-house 155-213 (213) Show / Hide
Range on Protein: 195-253
Range on HMM: 155-213/213
Sequence Identity: 35% (21 aa)

PGT-VAAMYEALGGQVHYVGKPHALVYDKTLEQLaGVPKSRIVAVGDSLHHDIEGALKAG
.|. |.|.  | . ... ||||..| . ..|..| ||  ...| .|| .. |..|| |.|
vGafvkaLeyatdveaevvGkPsklfFesalqel-gvdpeeavmiGDDvkdDvgGAqkvG

Phosphatase Mbre_s22.AA Subfamily.LHPP.PD 24-79 33 5.3e-09 23.6 In-house 4-60 (213) Show / Hide
Range on Protein: 24-79
Range on HMM: 4-60/213
Sequence Identity: 33% (19 aa)

FVLDQYGVIHNGSAPYPHAVEVVQRLRQAGKTVTILSNSSKPAHF-AHARLIEWGFG
..||  ||... .|. |..|| ..||.|.| .| ...| .| ..   . ||.. || 
vllDlsGvlyveeaaipgsveAlkrLkqsglkvrfvtnttkeskrelverLqrlgfk

Sequence
Name Sequence Type Origin Length Description Download
Mbre_s22.AA Protein None 305 None Fasta, JSON
Mbre_s22.NA RNA None 915 None Fasta, JSON
Mbre_s22.AA.PD2_211-253 Protein Phosphatase Domain None 43 None Fasta, JSON
Mbre_s22.AA.PD1_27-63 Protein Phosphatase Domain None 37 None Fasta, JSON