Gene mbre_9730
mbre_9730
Species: M.brevicollis
Alias: mbre_9730
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_9730.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | mbre_9730.AA | PP2Cc | 1-198 | 18 | 4.2e-08 | 24.65 | SMART | 9-338 (338) | Show / Hide |
Range on Protein: 1-198
Range on HMM: 9-338/338
Sequence Identity: 18% (63 aa)
MHSGP-------------DRIFSFK------------------------VTEN-----------------------------------KWCERAKSANDT
...| |. . . . |. .....| . |
WRYGYMESSMQGWRHPMEDAHVCRPFFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDKWFEDWEDALRKAFLRMDE
AGSCSTAVVVKGSQVYCGNAGDSKALLFQINE--THGV---NPVELNERHGTNLKSERKRILAAGG--------KIAPDG----SVYGV---LFPSRGFG
. .. . ....| ..|..|.||| | |.. .. ..|. ...| | | . .||.|| .||| . .. | || | .|| ||
EICTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFG
DIDVKADG---------------------KPVVICTPNGAGIDDWQPHRLE-----HSEATWLVVASDGLWDFVVDDQVMSIVAK---------------
| . | .| ||..| | . |.| .. |. ..|||||.. ...| .|| |
DHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEP------DVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQ
----------NQHLDHSAIAKKLIDEARLCGSEDDITIIVV
.| | ...||.|.|.|. .|..|.|||
ENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV
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| Phosphatase | mbre_9730.AA | Family.PPM.PD | 9-208 | 33 | 4e-46 | 147.6 | In-house | 100-294 (495) | Show / Hide |
Range on Protein: 9-208 Range on HMM: 100-294/495 Sequence Identity: 33% (69 aa) FSFKVTENKWCERAKSAN--DTAGSCSTAVVVKGSQVYCGNAGDSKALLFqinetH-GvNPVELNERHGTNLKSERKRILAAGGKIAP-DGSVYGVLFPS ..|. ......| ..... ...|.... |...|...|..|||||.|.|. . | ..|||.. | .. ..||.|| .||||. || | ||| .| kafleldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLc-----rng-kavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavs RGFGDIDVKAdGKPV-VICTPNGagiddwQPHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQ---HLDHSAIAKKLIDEARLCGSEDDITIIVVRY |..|| |.| . . |...| . ..|...|. ||.||||||| . ...|...| .. . | ..||..|.||| ||.|.||..|| . RalGdfdlkk-eeqaivsaePdi------tsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvval DFAIPQNS . .| |.. yenikqqn |
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| Phosphatase | mbre_9730.AA | Group.PPM.PD | 10-201 | 31 | 1.7e-45 | 145.6 | In-house | 128-322 (459) | Show / Hide |
Range on Protein: 10-201 Range on HMM: 128-322/459 Sequence Identity: 31% (63 aa) SFKVTENKWCERAKSAN---DTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINethgvNPVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRG .|. ......| |.... ...|.... ....|...|..|||||.|.| . . ..|.| . | .. ..||.|| .|||.. || | |.| .||. afleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrng-----kavplskdHkpenpeEreRIekagGsveidgRvnGilavsRa FGDIDVKAdGKPVVICTPNGAgiddwqPHRLEHSeATWLVVASDGLWDFVVDDQVMSIVAKNQHL-------DHSAIAKKLIDEARLCGSE------DDI .||.|.| ....|...| ..|.. . ||.||||||| . ...|...|... . | ..||..|.|||. ||.|.||.|||. lGdhdlkk-eeqmvsaePdvs------vvkltee-deflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNi TIIVVRYD .. Tvivvtln |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1A.PD | 21-201 | 27 | 2.7e-29 | 92.5 | In-house | 105-279 (309) | Show / Hide |
Range on Protein: 21-201 Range on HMM: 105-279/309 Sequence Identity: 27% (51 aa) RAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINethgvNPVELNERHGTNLKSERKRILAAGGKIApDGSVYGVLFPSRGFGDIDVKADGKP-- . .. .| .|| ...|.|. ..|. |.|||.|.|.. . . | | | . ..|..|| .|||.. . | | | || .|| || . . elskgedksGsTavvvlvspkklylancGDsRavlsrng-----kvvfateDHkpsdpkEkeRienAgGsvm-ikRvnGsLAvsRalGDydykekpekka ---VVICTPngagidDWQPHRLeHSEATWLVVASDGLWDFVVDDQVMSIVAKN--QHLDHSAIAKKLIDEARLCGSEDDITIIVVRYD .|. | . . . ..| ..||.|.||.|| . ...|...|... . | ...|..|.|.. ||.| ...|.| .. teqlvspep------evtvier-deedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvllp |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1E.PD | 10-198 | 33 | 7.4e-28 | 87.6 | In-house | 90-267 (269) | Show / Hide |
Range on Protein: 10-198 Range on HMM: 90-267/269 Sequence Identity: 33% (64 aa) SFKVTENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQinethGVNPVELNERHGTNLKSERKRILAAGGKIAPDGS--VYGVLFPSRGF .||.|... ...|.. . ..|| . .|.....|.| . |||.||| . .. |.| . | . . |.||| .||| . | |||| || | afkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvr-----kgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRai GDIDvkadGKPVVICTPNGAGIDdwqphrLEHSEaTWLVVASDGLWDFVVDDQVMSIV---AKNQHLDHSAIAKKLIDEARLCGSEDDITIIVV | . || |. .. | .. |..|| .|..|.||||| | ...|...| ..... |.| .||.|...|.||.|.||..|| GDvk----lkpyvsgeadvaeve------ldgse-dylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvv |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1L.PD | 15-199 | 34 | 1.1e-25 | 80.7 | In-house | 99-272 (273) | Show / Hide |
Range on Protein: 15-199 Range on HMM: 99-272/273 Sequence Identity: 34% (64 aa) ENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINethGvNPVELNERHGTNLKSERKRILAAGGKIAPDGS--VYGVLFPSRGFGDIDV ..| |.||.|.|.||. . .|..|.. | |||. .|.. . | . . | | . ||||| ||| || .|. | ||||| .|| .| dekllekakraediaGttalialvqesdlivanvGdsrGvlydkr---G-kaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdypl KAdgKPVVICTPNGAGIDdwqphrLEHSEATWLVVASDGLWDFVVDDQVMSIVAknQHLDH-SAIAKKLIDEARLCGSEDDITIIVVR | .|| .|. .| |.. . .|..||||||| ... . . ..|. || |. |. || |.||..||. kd--knlviadpdiltfd------lddhkpeflilasdGlwdtfsneeavrfik--erlkepdfGakslvlesfkrGsvdnitvlvvk |
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| Phosphatase | mbre_9730.AA | PP2C | 21-193 | 27 | 1.6e-24 | 89.93 | Pfam | 100-284 (284) | Show / Hide |
Range on Protein: 21-193 Range on HMM: 100-284/284 Sequence Identity: 27% (53 aa) RAKSAN------DTAGSCSTAVVVKGSQ--VYCGNAGDSKALLFQINETHGVNPVELNERHGTNLKSERKRILAAGGKIAP--DGSVYGV-LFPSRGFGD .....| .. |.. . ... ... |. |.||| |.| . ...| ...| . | . .||.|| .||| . . . | || | || ||| PWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNW-VHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGD IDVKADG-----KPVVICTPNGAGIDDWQ-PHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQHL--DHSAIAKKLIDEARLCGSEDDI . | . ...|...| | . |... .. |. |.||||| . |..| .|| .. . | . ...||.|... ||||.| FHYKPNHTCFPKEQPVTAEP------DITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | mbre_9730.AA | Subfamily.LRR-PP2C.PD | 11-200 | 28 | 3e-24 | 75.9 | In-house | 85-257 (257) | Show / Hide |
Range on Protein: 11-200
Range on HMM: 85-257/257
Sequence Identity: 28% (54 aa)
FKVTENKWCERAksanDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHgvnpVELNERHGTNLKSERKRILAAGGKIAPD---GSVYGVLFPSRGF
.| .. . ||. |. ...|.. . .|| | |||...| | . | . | | . .||.||| ..||.. .| | | || .||. .
ykeistqiserp----kfiGttaasvliiedkvyianvGdsrvvlcqkdgta----krlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsral
GDIDVkadgKPVVICTPNGAGiddwqpHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQHLDHSaiAKKLIDEARLCGSEDDITIIVVRY
.| |. |. . . . .|..| ||.|| . |.. ..|||. . ... |.|| || ||.|.|..||...
Gdsfl----ePfvvpdPdlsq------sleiskkdkflilacdGiwdlisdeeaveivagisdpeka--aeklrdlayssGstdnisvivikl
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1G2.PD | 11-189 | 28 | 4e-23 | 72.0 | In-house | 88-260 (275) | Show / Hide |
Range on Protein: 11-189 Range on HMM: 88-260/275 Sequence Identity: 28% (52 aa) FKVTENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINEthgvnPVELNERHGTNLKSERKRILAAGGKIAPDgSVYGVLFPSRGFGDI |. |... . | ....||| ...|..| ...|..|||||.|.| . . | | . .||.||| |||| .. . | |.| || .|| fletDeellkdeklkdesaGstavvvlikeeklyvanaGDsravlsskgn-----vkalsfDhkPqeesekkriiaagGfveln-rvngnLalsralgDf DVKADGKpvviCTPN---GAGIDDWQPHRLEhSEATWLVVASDGLWDFVVDDQVMSIVAKN--QHLDHSAIAKKLIDEARLCGS | | .|. . | ..|. .. .||.| ||.|| . ...|. .| .. .. . ..|...|.|..| efkknvk----kkpeeqivtavPDvlvkkld-eddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapds |
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| Phosphatase | mbre_9730.AA | Subfamily.ILKAP.PD | 10-168 | 33 | 4.8e-23 | 72.0 | In-house | 96-251 (298) | Show / Hide |
Range on Protein: 10-168 Range on HMM: 96-251/298 Sequence Identity: 33% (55 aa) SFKVTENKWCERAKSANDT--AGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHG------VNPVELNERHGTNLKSERKRILAAGGKIApDGSVYGVL .|| |... ..|..|. . || .. |.| . .| .| |||||.| .| ...| | . | . . ||||| ||| .|| | ||| afkktDeeflklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvr-dgRvlGvl FPSRGFGDIDVKADGkpvVICTPNgagiddWQPHRLEHSeATWLVVASDGLWDFVVDDQVMSIVAKN || .|| | | ||.||. . |.. ..|.| ||||. . |.|.. . | evsRsiGDgrfkelg---vistPd------vkkceLten-DlfvvlaCDGLwkvfeadevvkfilkv |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1K.PD | 23-199 | 27 | 1e-19 | 60.9 | In-house | 98-263 (264) | Show / Hide |
Range on Protein: 23-199 Range on HMM: 98-263/264 Sequence Identity: 27% (50 aa) KSANDTAGSCSTAVVV-KGSQVYCGNAGDSKALLFQINEThgvnpVELNERHGTNLKSERKRILAAGGKIAPDG----SVYGVLFPSRGFGDIDVKADGk .. ..|. .| ... .| .. . |||.|.| . .. | . | . |.|..||.||||... . | ..| .| .||.|.| | eaellssGttatvsllrdGnelvlaslGdsrailcrnGka-----kkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryG- pvVICTPNGAGIddwqphRLEHSEATWLVVASDGLwDFVVDDQVMSIVAKNQHlDHSAIAKKLIDEARLCGSEDDITIIVVR || ||. . ...|.. ..||. .||. .|||..| .. . . | | |. . . | ||||. |..|| --viatPetksl------kvkhaadsflvlitdgi-sfvvnsqelcdlvrlch-dpeeaahavteqalqygsednatavvvp |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1G.PD | 23-183 | 29 | 8.2e-19 | 58.2 | In-house | 297-459 (482) | Show / Hide |
Range on Protein: 23-183
Range on HMM: 297-459/482
Sequence Identity: 29% (49 aa)
KSANDTAG--SCSTAVV--VKGSQVYCGNAGDSKALLFQInethgVNPVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVKADGKp
.... | | .|||| |||.... |||||.. | . . ..| | . . |..|| .||||. || | | | || .||| . . .
lgkseepGkdsGttavvaLvkgkklivanaGDsRcvlsrn-----GkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktnee-
VVICTPNGAGIDDWQPHRLEHsEATWLVVASDGLWDFVVDDQVMSIVAKNQH-----LDHSAIAKKLIDE
. . | . . | . | .||.|.||.|. . ..|. | .. . | | .|.|.
LpaeeqmisalPDikklilte-edeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDa
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1D.PD | 14-100 | 23 | 6.9e-15 | 45.2 | In-house | 99-186 (311) | Show / Hide |
Range on Protein: 14-100 Range on HMM: 99-186/311 Sequence Identity: 23% (21 aa) TENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINE-THGVNPVELNERHGTNLKSERKRILAAGGKIAPDGSVYGV . ..| .... |||. . |.......| .. |||...| . .. .. ... || . | . .|..|| .||..| |. | klaeWpktksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRv |
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| Phosphatase | mbre_9730.AA | Subfamily.PDP.PD | 15-115 | 25 | 1.1e-13 | 41.4 | In-house | 151-256 (409) | Show / Hide |
Range on Protein: 15-115 Range on HMM: 151-256/409 Sequence Identity: 25% (27 aa) ENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHGVNPVELNERHGTNLKSERKRILAAGGKI-----APDGSVYGVLFPSRGFGD |.| |.| . ..|.|.......| ... |.||..|.| . .|. ...|.|.. . .. ..| .|| .. . .| . | |.|.| ||| eekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGd IDVKAD . | . vryKws |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1H.PD | 103-185 | 26 | 3.1e-10 | 29.6 | In-house | 285-376 (402) | Show / Hide |
Range on Protein: 103-185 Range on HMM: 285-376/402 Sequence Identity: 26% (25 aa) PSRGFGDIDVKADG-----KPVVICTPNgagIDDWQPHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAK-------NQHLDHSAIAKKLIDEAR .||.|| ..|. ||.. ..|. . .. . .|..| |..|.||||| . ...| ||.. ... ..|.|..|..|| vtRGlGDheLkvvdtnlsikPfLspvPe---vrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkrytavaqeLvaaar |
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| Phosphatase | mbre_9730.AA | Subfamily.PHLPP.PD | 63-198 | 25 | 1.3e-08 | 24.4 | In-house | 134-257 (257) | Show / Hide |
Range on Protein: 63-198 Range on HMM: 134-257/257 Sequence Identity: 25% (35 aa) GVNPVELNERHGTNLK-SERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVkadgKPVVICTPNGAGIddwqphRLEHsEATWLVVASDGLWDFVVDDQV . |. | . . . | ||| | . | |. | ||. .| .| . . |||. .|. . |.. . .|.. ...||. . |.. nGkplplskvyileiddeelkrikeakaiitednkvnGviestrilGytfl----fPvvlPkphvrsv------lLte-qdEllilGnkalWevlsidea MSIVAKNQhlDHSAIAKKLIDEARLCGSEDDITIIVV . | ... | ..||||.| | | .|.....|| veavrnve--dplvaAkklvdlaqsygaadsvsalvv |
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| Phosphatase | mbre_9730.AA | Subfamily.TAB1.PD | 30-113 | 22 | 4.3e-08 | 22.6 | In-house | 138-222 (336) | Show / Hide |
Range on Protein: 30-113 Range on HMM: 138-222/336 Sequence Identity: 22% (20 aa) GSCSTAVVVKGSQVYCGNAGDSKALLFQINETHgVNPVELNERHGTNLKSERKRILAAG---GKIAPDGsVYGVLFPSRGFGDIDVK |. ... . | | |||.|.| . .. . .. . |. |... . | ||. | ..| . . | . | || .| GttavvalilnnkLyvaNvGdsrAilvesekdg-ikvkQLsvdHnvdNedElkRlkdLGldieqikqnk-rlgskeaTRsiGdykik |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1D.PD | 134-174 | 30 | 3.4e-07 | 19.9 | In-house | 236-276 (311) | Show / Hide |
Range on Protein: 134-174 Range on HMM: 236-276/311 Sequence Identity: 30% (11 aa) PHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQHLDHS ..|. .| ....||||||. . ....|.| |... vrtldpneekfiilasDGlwnvltpedavsvvekeeekkel |
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| Phosphatase | mbre_9730.AA | Subfamily.PDP.PD | 140-174 | 37 | 4.3e-07 | 19.7 | In-house | 297-329 (409) | Show / Hide |
Range on Protein: 140-174 Range on HMM: 297-329/409 Sequence Identity: 37% (13 aa) SEATWLVVASDGLWDFVVDDQVMSIVAknQHLDHS .. .||.|.|||||.. ...|.|.| .||... endkFLvlatDGLwdllsneevvslVg--ehlakk |
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| Phosphatase | mbre_9730.AA | Subfamily.PPM1H.PD | 20-85 | 28 | 7.5e-07 | 18.4 | In-house | 154-213 (402) | Show / Hide |
Range on Protein: 20-85 Range on HMM: 154-213/402 Sequence Identity: 28% (19 aa) ERAKSANDTAGSCSTAVV-VKGSQVYCGNAGDSKALLFQINEThgvnpVELNERHGTnlKSERKRIL .| ..| ..| |.. |. | ..| |||||.|.| . .|. ..| . . ..||.|.. arereayrikGGCtalvalvllgklYvanaGDsRailvrkdei-----iplsadftP--eteRqRlq |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_9730.AA | Protein | None | 217 | None | Fasta, JSON |
| mbre_9730.NA | RNA | None | 651 | None | Fasta, JSON |
| mbre_9730.AA.PD_1-201 | Protein Phosphatase Domain | None | 201 | None | Fasta, JSON |