Gene mbre_12489
mbre_12489
Species: M.brevicollis
Alias: mbre_12489
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_12489.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Myb_DNA-binding | mbre_12489.AA | SANT | 811-859 | 33 | 1.3e-13 | 52.52 | SMART | 1-53 (53) | Show / Hide |
Range on Protein: 811-859 Range on HMM: 1-53/53 Sequence Identity: 33% (18 aa) KDGPFVPSEDRILLQAQMQHG----NDWIEVAKMLPGRTDEAIRLRWQELSSV | ||. . ||..|..| ..| |.| ..||..|.||.. .|.||... . KKGPWTEEEDELLIEAVKKYGKNTHNNWKKIAKHMPNRTPNQCRNRWYNWKKP |
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| Phosphatase | mbre_12489.AA | PP2Cc | 1083-1428 | 12 | 6.2e-14 | 53.54 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 1083-1428
Range on HMM: 1-338/338
Sequence Identity: 12% (53 aa)
VQPGPDASNDAASATPAAGGRPNASVNQDSYFLTSGRLAGVGRFSLAAVFDGHSPGGERASQCAADTLNKIVGAAVRREADRLPELVANHRLELWEH---
.. . .|. . . . .. . ..|... . . .||||| | ...| ... | ... . ..|.. . .. .. .
HS-MGYNSGWRYGY-MESSMQGWRHPMEDAHVCRP----------FFGVFDGHG--GHECAQYCRKHLHEHLAEELQFHKDDDYKEND-E-MQ-D-EPEM
--------VAHEPDTLLKAIFKRLHTAIIDDYAQWPAEYEYTQGGQLHRFARLDHPKWGQCIVRHDGHTSPLDYGTTAAIALLLHLSDDRMMFACAHAGD
. . .|. |.|.. .| .|| .||. . .|..||
WWRMWHDKWFEDWEDALRKAFLRMDEEI-----------------------------------------------CTAVVALIRGNK-----LYVANVGD
SLVALARCNQPLKADGL---DLGYVTRRHNLHSADERERVAS----VLGQRGHVTEDHYLAIDDEAD-----LRAHQ---VQISKSLGHKQLSA------
| . | | .. | . .|. |. .|||.|. |. . . . . . ..| ..| ...
SRAVLCRNGND-NWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVM--------P-MHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKI
-----------------YGVSFEPDCYVRVLD-----ADETFAILVVSDGITDGLKRDVILDVLARTA---------------------------TAQEA
..|. ||| ... |. .. .. .||..| . . . |.. .. ..||
EWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEA
AQQLCDDAHANNMLAVNSSDDCTAVLL
|. ||| | .|..|....
AKRLCDCAI---------CDNMTVIVV
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| Myb_DNA-binding | mbre_12489.AA | Myb_DNA-binding | 812-857 | 40 | 8.9e-13 | 52.92 | Pfam | 1-50 (50) | Show / Hide |
Range on Protein: 812-857 Range on HMM: 1-50/50 Sequence Identity: 40% (20 aa) DGPFVPSEDRILLQAQMQHGND--WIEVAKMLP--GRTDEAIRLRWQELS ||. | ||..|..| ..|||. | ..||..| ||||. .|..|. . RGPWTPEEDEKLIEAHKKHGNRANWKKIAKHMPGLGRTDNQCRNHWNNYL |
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| Phosphatase | mbre_12489.AA | Family.PPM.PD | 1110-1430 | 20 | 6e-40 | 125.1 | In-house | 30-286 (495) | Show / Hide |
Range on Protein: 1110-1430
Range on HMM: 30-286/495
Sequence Identity: 20% (69 aa)
QDSYFLTSGRLAGVgRFSLAAVFDGHSpgGERASQCAADTLNKIVGAAVRREADRLPELVANHRLelwehvaHEPDTLLKAIFKRLHTAIIDDYAQWPae
.|... .. . .||| .|||||. |..|...||..| ||. . .... |.... |... .. .. |. |..|.... .......
eDahvvvenlenne-dfslfgvfDGhg--Gaeaaefaakklhkilkkqlekkddeksstsaessa-------ekvkealrkafleldeelseelneks--
yeytqggqlhrfarldhpkwgqcivrhdghtSPLDYGTTAAIALLlHLSDdrmmFACAHAGDSLVALARCNqplkadglDLGYVTRRHNLHSADERERVA
.. | ||||...|. . .. .|.|||| . | |.. . ... |. .. .||||.
-------------------------------agkdsGtTAvvvli-rgkk----lyvAnaGDsravLcrng--------kavelskdHkpenpeEreRIe
SVLGQrghvtedhyL-AiddeADLRAH-QVQISKSLGHKQLSA---YGVSFEPDCYVRVLDADETFAILVVSDGITDGLKRDVILDVLARTA-----TAQ
. |. . | | . ....|..||. .|. ..|| |||. . |. .|. . ..|||. | |. ...... .| ...|
kagGk---------vvi----rdgrvnGvlavsRalGdfdlkkeeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedle
EAAQQLCDDAHANNmlavnSSDDCTAVLLCL
.|..|.| |.|.. |.|..|.....|
eiaeeLvdealakg-----srDNiTvlvval
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| Phosphatase | mbre_12489.AA | Subfamily.PPM1K.PD | 1239-1427 | 26 | 1.4e-11 | 32.2 | In-house | 98-261 (264) | Show / Hide |
Range on Protein: 1239-1427 Range on HMM: 98-261/264 Sequence Identity: 26% (48 aa) HTSPLDYGTTAAIALLLhlsdDRMMFACAHAGDSLVALARCNQPLKadgldlgyVTRRHNLHSADERERVASVLGQRGHVTEDHYlaiddeadLRAHQVQ ... |. ||||...|| | . .. | ||| | | .. | .|. |. . .|.||. .. |. . ..| .. ...||| . eaellssGttatvsllr----dGnelvlaslGdsrailcrnGkakk--------ltkdhdPerkeekerikaagGsvewnslgkp--------lvnsrla ISKSLGHKQLSAYGVSFEPDCY-VRVLDADETFAILvVSDGITDGLKRDVILDVLARTATAQEAAQQLCDDAhannmLAVNSSDDCTAVL | ||| .|. ..| |...| .| ..|||.. .. . |.. .|||. ... | || |..|||. mtrslGdldlkryGviatPetkslkvkhaadsflvl-itdgisfvvnsqelcdlvrlchdpeeaahavteqa-----lqygsednatavv |
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| Phosphatase | mbre_12489.AA | Subfamily.PPM1D.PD | 1244-1402 | 24 | 5.5e-07 | 17.1 | In-house | 113-277 (311) | Show / Hide |
Range on Protein: 1244-1402 Range on HMM: 113-277/311 Sequence Identity: 24% (41 aa) DYGTTAAIALLLhlsdDRMMFaCAHAGDSLVALARCNQplKADGLDLGYVTRRHNLHSADERERVASVLGQRGHV-------TEDHYLAIDDE-ADLRAH ||||.. .. . .. || ||| . |. .. | . | .|. | .| .|.||.... |. . . . |... . ... taGttasvviir----rekly-vahvGDsgivlgvkep--kekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprlehngptvideiP QVQISKSLG-----HKQLSAYGVSFEPDCYVRVLDADETFAILVVSDGITDGLKRDVILDVLARTATAQEAA ..||| .. .| || ||| .||.|| .|. |.. |||... |. . .|. .. . .| FLavaRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelk |
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| Phosphatase | mbre_12489.AA | Subfamily.LRR-PP2C.PD | 1243-1412 | 24 | 8.8e-07 | 16.6 | In-house | 97-244 (257) | Show / Hide |
Range on Protein: 1243-1412 Range on HMM: 97-244/257 Sequence Identity: 24% (39 aa) LDYGTTAAIALLLhlsDDRmmFACAHAGDSLVALArcnqplKADGLDlGYVTRRHNLHSADERERVASVLgqrGHVTEDhylaidDEADLRAHQVQISKS ||||| .|.. .|. | ||| | |. . || .. |. .|..|.. . | | ... .. .|..|| |. . | kfiGttaasvlii---edk--vyianvGdsrvvlc------qkdgta-krlsldhkPseeseekriselG---Gtvvst------vvtsrvnGtlavsra LGHKQLSAYGVSfEPDCYV-RVLDADETFAIlVVSDGITDGLKRDVILDVLARTATAQEAAQQLCDDAHAN . .|| .. | | . ||| | . . ...| . ...||..| | |. . lGdsflePfvvp-dPdlsqsleiskkdkfli-lacdGiwdlisdeeaveivagisdpekaaeklrdlayss |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_12489.AA | Protein | None | 1430 | None | Fasta, JSON |
| mbre_12489.NA | RNA | None | 4290 | None | Fasta, JSON |
| mbre_12489.AA.PD_1083-1428 | Protein Phosphatase Domain | None | 346 | None | Fasta, JSON |