• Phosphatome.Net

Gene mbre_34068

mbre_34068
Species: M.brevicollis
Alias: mbre_34068
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: PPM_Unclassified
Protein domain

Protein domains of mbre_34068.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase mbre_34068.AA PP2Cc 424-744 19 1.6e-38 135.19 SMART 1-338 (338) Show / Hide 
Range on Protein: 424-744
Range on HMM: 1-338/338
Sequence Identity: 19% (80 aa)

PSTSPTIQVPEYGAYSMGGGYAGNPKENQDGFLVYEGSSALPFLAAVMDGHGVNGRKVSGFAESTLGVEILESYRQNQAL--------------------
.| ..    . ||   |     |......| ....        . .| ||||  | ... .. . |  |.|... |...                     
HS-MGYNSGWRYGY--MESSMQGWRHPMEDAHVCRP-------FFGVFDGHG--GHECAQYCRKHLH-EHLAEELQFHKDDDYKENDEMQDEPEMWWRMW

--------SEALVNGIVSTAAKLRKSTIDARESGTTAVVCARTPDGRQLIVANVGDSRCVLGRCLGGSR------YQPIPLSRDHKPSDPGERQRIQRAG
         .|| ... ..  ..           .||||.  ...   |.||||||||.||.|  .. .      |....|..||||... ||.||..||
HDKWFEDWEDALRKAFLRMDEEI-----------CTAVVALIRGNK--LYVANVGDSRAVLCRNGND-NWWGIRHYTAHQLTEDHKPDNEDERRRIEQAG

GYVEPTRVRGWGFQGPARVWRRRQQEGGLALSRSVGDFHLF-----------------------EAGVVAEPELQIHAGRQYLGRGPGLWTRSSIARHIA
| |.|   |.|  ...  |||   . ..||.||. ||....                       | .|.|||. ..|   | .                 
GRVMP-MHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMT-----------------

YQHPLTSDVPLGLDRKLEKTLDSQDHFIVLGSDGVFDHLSNAQVILFLAK-------------------------YQEGADFVITSNSLECHLSSQNSAK
                  .  ...| |..|..||..|..|| .|. .. |                          . ...  .  .  .| . . |   
------------------V-PTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI-CDNMTV

IRL
| .
IVV
Phosphatase mbre_34068.AA Group.PPM.PD 426-755 28 3.1e-54 174.4 In-house 31-280 (459) Show / Hide 
Range on Protein: 426-755
Range on HMM: 31-280/459
Sequence Identity: 28% (87 aa)

TSPTIQVPEYGAYSMGggyaGNPKENQDGFLVYEGSSAL-PFlAAVMDGHGvnGRKVSGFAESTLGVEILESYRQN-------------------QALSE
... ..   ||. ||     |. ||..| . ..|  .    |  .|.||||  |.... ||...|   .... ...                   ....|
sagsgnglrygvasmq----gwrkemEDrhvivenfdnndsf-fgVfDGHg--GaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkk

ALVNGIVSTAAKLRKSTIDAR----ESGTTAVVCARtpDGRQLIVANVGDSRCVLGRClGgsryQPIPLSRDHKPSDPGERQRIQRAGGYVEP-TRVRgw
| ...  . ..|...  ...    .|||||||.    .|..|.|||.||||.||.|. |    ...|||.||||..| ||.||..|||.||||       
alrsafleldedlseeanekeepgkdsGtTAvvali--ngkklyvANaGDSravLcrn-g----kavplskdHkpenpeEreRIekagGsveidgRvn--

gfqgparvwrrrqqeGGLALSRSVGDFHLFEaG---VVAEPELQIHAGRqylgrgpglwtrssiarhiayqhpltsdvplgldrklektldSQDHFIVLG
           |.||.||..||..| . .   | |||. . ...|.|.||.|||..| ||| .|. |.... |                           
---------------GilavsRalGdhdlkk-eeqmvsaePdvsvvklt------------------------------------------eedeflvlA

SDGVFDHLSNAQVILFLAKYQEGadfvitsnslechlssqnsakirlkfgeklnklfR
        .                                                 
sDGlWdvlsneevvefvretlek----------------------------------k
Phosphatase mbre_34068.AA Family.PPM.PD 429-734 28 8.3e-49 156.4 In-house 11-270 (495) Show / Hide 
Range on Protein: 429-734
Range on HMM: 11-270/495
Sequence Identity: 28% (89 aa)

TIQVPEYGAYSMGgGyagNPKENQDGFLVYEGSSAL-PF-LAAVMDGHGvnGRKVSGFAESTLGVEILESYRQN-------------QALSEALVNGIVS
..  .||..||  |   . .|..| . |.|. .   .| | .|.||||  |.... ||...|   .... ...             . ..||| ... ..
ssnglrygvasmq-g---wrsemeDahvvvenlennedfslfgvfDGhg--Gaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafle

TAAKLRKSTIDAR---ESGTTAVVCARtpDGRQLIVANVGDSRCVLGRClGgsryQPIPLSRDHKPSDPGERQRIQRAGGYVEPtrvrgwgfqgparvwR
 ..|...  ...   .|||||||.     |..|.|||.||||.||.|. |    ....||.||||..| ||.||..|||.|.|. . .|.||.||..|||
ldeelseelneksagkdsGtTAvvvli--rgkklyvAnaGDsravLcrn-g----kavelskdHkpenpeEreRIekagGkvvi---------------r

RRQQEGGLALSRSVGDFHLFE---AGVVAEPELqihagrqylgrgpglwtrssiarhiayqhpltsdvplgldrkLEKTLD-SQDHFIVLGSDGVFDHLS
.| .   |.|.|||.                                              .|. ..|.|.|| |||..| ||| .|. .. ..   ...
dgrvnGvlavsRalGdfdlkkeeqaivsaePdi------------------------------------------tsvkltqeedeflvlasdGlWdvls

NAQVILFLAKYQ--EGADFVITSNSLECHL
|.   ...|  .                  
neevvelvretleekeedleeiaeeLvdea
Phosphatase mbre_34068.AA PP2C 437-643 25 2.8e-31 114.3 Pfam 1-224 (284) Show / Hide 
Range on Protein: 437-643
Range on HMM: 1-224/284
Sequence Identity: 25% (63 aa)

AYSMGGGYAGNPKENQDGFLVYE------GSSALPFLAAVMDGHGVNGRKVSGFAESTLG---VEILESYRQNQAL-----SEALVNGIVS--TAAKLRK
  .... . |  ... |. . |       ..     . || ||||  |.... .....|     .||.. ..   .     ..|| ... .  |. ....
WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHG--GHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYS

--STIDA------RESGTTAVVCARTPDGRQLIVANVGDSRCVLGRCLGGSRYQPIPLSRDHKPSDPGERQRIQRAGGYVE---PTRVRGWGFQGPARVW
   ....        ||.|||..  ...   |.|||.||||.||.|  |... .. .|..|||||.. || ||..|||.|.    .||.|          
APWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCR-NGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGV---------

RRRQQEGGLALSRSVGDFHLFE--------AGVVAEPELQ-IH
       .||.||. ||||..          .|.|||. .  |
-------WLAVSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEH
Phosphatase mbre_34068.AA Subfamily.PPM1G2.PD 467-714 36 2.4e-30 95.7 In-house 45-234 (275) Show / Hide 
Range on Protein: 467-714
Range on HMM: 45-234/275
Sequence Identity: 36% (79 aa)

LAAVMDGHGvnGRKVSGFAESTLGVEILE--SYRqNQALSEALVNGIVSTAAKLRKS-TIDARESGTTAVVCARTPDGrqLIVANVGDSRCVLgrCLGGS
| ||.||||  |.||. .| . |   | .  |.. ..||...| .....|  .|.|  ...  ..|.||||   . .   |.|||.||||.||  .  |.
lfavfDGhG--Gakvakyagkklikkiakkksfk-egaleqilkdafletDeellkdeklkdesaGstavvvlikeek--lyvanaGDsravl--sskgn

ryqPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVrgwgfqgparvwrrrqqEGGLALSRSVGDFHlFEAGVVaepelqihagrqylgrgpglwtrssiar
      ||.||||.. .|..||. |||.||  ||                  | |||||..|||. |  .|..|    |    |  ..| ||..| |.||
---vkalsfDhkPqeesekkriiaagGfvelnrv-----------------ngnLalsralgDfe-fkknvk----------------------------

hiayQHPLTSDVPLGLDRKLEKtLDSQDHFIVLGSDGVFDHLSNAQVILFL
  ||..| |.|..|. ..                                 
----kkpeeqivtavPDvlvkk-ldeddeflvLaCDGiWDvltnkevvdlv
Phosphatase mbre_34068.AA Subfamily.PPM1A.PD 469-599 38 5.4e-23 71.8 In-house 45-177 (309) Show / Hide 
Range on Protein: 469-599
Range on HMM: 45-177/309
Sequence Identity: 38% (55 aa)

AVMDGHGvnGRKVSGFAESTLGVEILES--Y------RQNQALSEALVNGIVSTAAKLRKSTIDAR---ESGTTAVVCARTPdgRQLIVANVGDSRCVLG
||.|||.  |.||| .....|  .|||.  .      .......||| .| ...  |.||..  ..   .||.||||.  .|  ..|..||.|||| || 
avfDGHa--GskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirklvelskgedksGsTavvvlvsp--kklylancGDsRavls

RclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRG
|   |   . .  ..||||||| |..||. ||| |   || |
r--ng---kvvfateDHkpsdpkEkeRienAgGsvmikRvnG
Phosphatase mbre_34068.AA Subfamily.PPM1K.PD 445-641 32 7.2e-23 71.2 In-house 18-199 (264) Show / Hide 
Range on Protein: 445-641
Range on HMM: 18-199/264
Sequence Identity: 32% (65 aa)

AGNPKENQDGFLVYEGSSALPFLaAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKLRK------STIDARESGTTAVVCArT
|  .||.| | . |    | .. || ||||  |     |.   |   . . . ... | | |..       ||..      .  .  .||||| |.    
iGkraenedrfklkeldpdllyf-avfdGhg--GssaadfvhdkleeivrrllekekdleevlkqafeeldkklkrylefsvaeaellssGttatvsl-l

PDGRQLIVANVGDSRCVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEptrvrgWGFQGPARVwrrrqqEGGLALSRSVGDFHLFEAGVVAEP
|| .|..|..|||| .| |   |   ..  |..||.|.   |..||..||| ||      |   |  .|      .. ||..||.||. | . ||.|.||
rdGnelvlaslGdsrailcr--nG---kakkltkdhdPerkeekerikaagGsve------wnslgkplv------nsrlamtrslGdldlkryGviatP

ELQ
 . 
etk
Phosphatase mbre_34068.AA Subfamily.PPM1G.PD 520-626 52 9.4e-22 67.9 In-house 299-382 (482) Show / Hide 
Range on Protein: 520-626
Range on HMM: 299-382/482
Sequence Identity: 52% (47 aa)

KSTIDARESGTTAVVCARtpDGRQLIVANVGDSRCVLGRClggsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEP-TRVrgwgfqgparvwrrrqqEGGL
||    ..|||||||.     |..|||||.||||||| |       . . || |||| |. |..||..||| |.   ||||| ||| .||          
kseepGkdsGttavvaLv--kgkklivanaGDsRcvlsrn-----GkaldlsiDhkPeDeveleRiekaGGkvtldgRv-----------------nGGL

ALSRSVGD
        
nlsRalGD
Phosphatase mbre_34068.AA Subfamily.PPM1L.PD 466-639 35 1.2e-21 67.5 In-house 43-205 (273) Show / Hide 
Range on Protein: 466-639
Range on HMM: 43-205/273
Sequence Identity: 35% (66 aa)

FLAAVMDGHGvnGRKVSGFAESTLGVEILESY------RQNQA---LSEALVNGIVSTAAKLR-KSTIDARESGTTAVVCARTpdGRQLIVANVGDSRCV
. ||.||||  |   . ||.. |  .|..        ..|.     |. |.. |.|   ||  | .    ..||||..   .  ...|||||||||| ||
sffavfdGhG--GefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraediaGttalialvq--esdlivanvGdsrGv

LGRCLGgsryQPIPLSRDHKPSDPGERQRIQRAGGYVeptrvrgwGFQGparVWRRrqqEGGLALSRSVGDFHLFEAGV-VAEPE
    |    . |||| |||| .. ||.||..|||..         |.|   |||    .| ||.||..||. | .  . .|.|. 
lydkrG----kaiplsfdhkpqqvkerkrikkaGGfi--------afrG---vwrv---aGvlatsralGdyplkdknlviadpd
Phosphatase mbre_34068.AA Subfamily.PPM1E.PD 469-640 31 7.6e-20 61.4 In-house 51-199 (269) Show / Hide 
Range on Protein: 469-640
Range on HMM: 51-199/269
Sequence Identity: 31% (53 aa)

AVMDGHGvnGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKL-RKSTIDARESGTTAVVCARTpdGRQLIVANVGDSRCVLGRclggsRYQP
||.||||  | . . .| . |   . .  ....   ||| ...  |  .. .|.. .. .||.||||.. .  ..|| || .|||. .| |. . | . |
avfDGHg--GveaakyaaahlhellvrqeklkedpaealkeafkltDerflqkaereklksGstavvvlie--kdqlyvaWlGDsqallvr-----kgea

IPLSRDHKPSDPGERQRIQRAGGYVeptrVrgWgFqGparVWRRrqqEGGLALSRSVGDFHLfEAGVVAEPEL
||... |..||. ||| |    |  . . |   .||     | |..||..|| .| .. |..|...       
vqlmkpHkPeredEkkRieeagGlv----v--v-i-g---awRv---nGvLsvsRaiGDvkl-kpyvsgeadv
Phosphatase mbre_34068.AA Subfamily.ILKAP.PD 469-640 31 8.7e-19 58.0 In-house 51-216 (298) Show / Hide 
Range on Protein: 469-640
Range on HMM: 51-216/298
Sequence Identity: 31% (58 aa)

AVMDGHGvnGRKVSGFAESTLGVEILESYRQ------NQALSEALVNGIVSTAAKLRKSTI---DARESGTTAVVCARTPDgrQLIVANVGDSRCVLGRC
|| |||.  |.. | ||...|   |.| . .      .. .  .||.   .|  .. | .     .  .|.||||.    .   | |||.|||. || |.
avfDGha--GsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklaskakPvWkdGstavvvlvvdn--vlyvanlGDskavlaRa

LGGSR------YQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEAGVVAEPEL
   ..      .....||.||.|..  ||.|||.|||.|.  || |                  |. |||.|| .  |.||...|..
keegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGv-----------------levsRsiGDgrfkelgvistPdv
Phosphatase mbre_34068.AA Subfamily.LRR-PP2C.PD 468-641 32 1.7e-18 57.0 In-house 43-192 (257) Show / Hide 
Range on Protein: 468-641
Range on HMM: 43-192/257
Sequence Identity: 32% (56 aa)

AAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA-LSEALVNGIVSTAAKLRKSTidaRESGTTAVVCARTPDgrQLIVANVGDSRCVLGRCLGGSRYq
|..||||  ||. . ||  .|   . |    |.|   ..| .   ..  .. . .   .  ||||..   . |  . ..|||||||||..  | ..    
yalfdGhg--GraaakfaseelykilaelldlnnanPlkslkkaykeistqiserp---kfiGttaasvliied--kvyianvGdsrvvlcqkdgtakr-

pipLSRDHKPSDPGERQRIQRAGGYVEPTrvrgwgfqgparvWRRRQQEGGLALSRSVGDFHLfEAGVVAEPELQ
 || |||||.. |..||...|| |  |                 . .| ||.||..|| .| |  ||..|.|.  
---lsldhkPseeseekriselGGtvvst-------------vvtsrvnGtlavsralGdsfl-ePfvvpdPdls
Phosphatase mbre_34068.AA Subfamily.PPM1D.PD 468-631 28 3.2e-16 49.5 In-house 44-220 (311) Show / Hide 
Range on Protein: 468-631
Range on HMM: 44-220/311
Sequence Identity: 28% (51 aa)

AAVMDGHGvnGRKVSGFAESTLGVEILES----YRQNQALSEALVNGIVSTAAKLRKSTI--------DARESGTTAVVCARTpdGRQLIVANVGDSRCV
||.||||  |.. . || . |  .| .      ...... ||. .. ..|  ...|.          .   .|||| |   .  ...| ||.||||. ||
vavfDGHG--GkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktksgllstaGttasvviir--reklyvahvGDsgiv

LGRCLG-GSRYQPIPLSRDHKPSDPGERQRIQRAGGYVEPT----RVRgWGF-QGPARVWRRRQQEGGLALSRSVGDFHLFE
|      .. .. .| .||||..| |..||...|| |       ||  |   .   .  . ...   ||..||.||.  .. 
lgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvv-WkRprlehngptvideiPFLavaRslGDlWsyn
MPPN mbre_34068.AA MPPN 910-989 20 1.8e-12 46.71 Pfam 12-143 (143) Show / Hide 
Range on Protein: 910-989
Range on HMM: 12-143/143
Sequence Identity: 20% (27 aa)

LACVTIFGFGLADLDLVMTEFERCGRILRR--------------------------------------------------ETKTNCNWLHVQFDDQLSAQ
.  ||.|||  ..  .|  .|.||| |.                                                     . || ||.|..    ..|.
DHAVTVFGFPPSITNMVIQHFSRCGHIMKHVQVIRDFRGFNPNNMRIFHNHDTGCDENDSTVNKSITLKSRNNESNNQKYPMPTNGNWMHMTYQCRSHAH

RALSKHGMVLSARLMVGVQPC--LDEEFLRNA
.||.| || .   .||.| .|   |.. .   
KALQKNGMIINGSVMVCVKYCPATDKQVMNCK
Phosphatase mbre_34068.AA Subfamily.PDP.PD 514-588 28 3.4e-12 36.5 In-house 151-223 (409) Show / Hide 
Range on Protein: 514-588
Range on HMM: 151-223/409
Sequence Identity: 28% (21 aa)

TAAKLRKSTIDARESGTTAVVCarTPDGRQLIVANVGDSRCVLGRCLGGSRYQPIPLSRDHKPSDPGERQRIQRA
.  .|.......  ||..|..     .|..| |||.||.|.|||.  . . .....||.|.  . . | .||...
eekvleeavlkvalsGacalla--liegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikke
Phosphatase mbre_34068.AA Subfamily.PPM1H.PD 499-588 31 2.5e-07 20.0 In-house 129-215 (402) Show / Hide 
Range on Protein: 499-588
Range on HMM: 129-215/402
Sequence Identity: 31% (30 aa)

QNQALSEALVNGIVSTA-----AKLRKSTIDARESGTTAVVCARTPDGrQLIVANVGDSRCVLGRCLGGsryqpIPLSRDHKPSdpGERQRIQRA
...  .| || | . .|      ....   . | .|  ... | . .| .| ||| |||| .| |.        ||||.|. |    ||||.|. 
ekkiskeeLviGalesaflemDeqiarereayrikGGCtalvalvllg-klYvanaGDsRailvrkdei-----iplsadftPe--teRqRlqel
Phosphatase mbre_34068.AA Subfamily.PDP.PD 685-722 31 1.6e-06 17.8 In-house 293-330 (409) Show / Hide 
Range on Protein: 685-722
Range on HMM: 293-330/409
Sequence Identity: 31% (12 aa)

KTLDSQDHFIVLGSDGVFDHLSNAQVILFLAKYQEGAD
. | ..|.|.||..|| .| ||| .|.    .. ....
hklrendkFLvlatDGLwdllsneevvslVgehlakkk
Phosphatase mbre_34068.AA Subfamily.TAB1.PD 527-589 36 1.8e-06 17.2 In-house 136-195 (336) Show / Hide 
Range on Protein: 527-589
Range on HMM: 136-195/336
Sequence Identity: 36% (23 aa)

ESGTTAVVCARtpDGRQLIVANVGDSRCVLGRCLGGSrYQPIPLSRDHKPSDPGERQRIQRAG
. ||||||        .| |||||||| .| .       .   || ||    . | .|..  |
sgGttavvali--lnnkLyvaNvGdsrAilvesekdg-ikvkQLsvdHnvdNedElkRlkdLG
Phosphatase mbre_34068.AA Subfamily.PPM1A.PD 686-717 38 7.4e-06 15.5 In-house 213-244 (309) Show / Hide 
Range on Protein: 686-717
Range on HMM: 213-244/309
Sequence Identity: 38% (12 aa)

TLDSQDHFIVLGSDGVFDHLSNAQVILFLAKY
. |..|.|.|| .||..| .||..|. |... 
erdeedeflvlacDGiwDvmsneevaefvksr
Sequence
Name Sequence Type Origin Length Description Download
mbre_34068.AA Protein None 1055 None Fasta, JSON
mbre_34068.NA RNA None 3165 None Fasta, JSON
mbre_34068.AA.PD_424-744 Protein Phosphatase Domain None 321 None Fasta, JSON