Gene Nvec_PTPN12
Nvec_PTPN12
Species: N.vectensis
Alias: Nvec_PTPN12, Nvec_83704
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Nvec_PTPN12.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | Nvec_PTPN12.AA | Subfamily.N6.PD | 20-289 | 36 | 5e-70 | 227.6 | In-house | 11-294 (295) | Show / Hide |
Range on Protein: 20-289 Range on HMM: 11-294/295 Sequence Identity: 36% (104 aa) ENGFAKEFQELKNISsrqkRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEI-KGVDGSDYINGNYI--------KGPTKNI-----MYLAAQGPL || .||.||.. | .| ..||| |..|||||.|||.| .|..| . . | ||||||.||| .| ... |.|.||.|.. tlgfweefeelqkqe----seklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcL PKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEETLtFAGMKISLESEEAMGDgFTVRTLAVQ---AGKTKHNVTQFHYTAWPDHDVPRSA || |||||. | .|.||. .|.| || || ||||.. ... . .... ||... | .|.|.. |. . |..... |.|..|||||.||... kdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstad-YtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdp TPLIELTRSFRT----FvgSQDTPVLVHCSAGCGRTGTICALDYART-LLQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELV .... . .. . .. |..||||||.|||||. .| . |.| .. . .. ..|.|| .|||..|||||||. .. gvvlnfledvnkkqeel--ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N12.PD | 23-289 | 60 | 9.1e-131 | 426.4 | In-house | 2-269 (270) | Show / Hide |
Range on Protein: 23-289 Range on HMM: 2-269/270 Sequence Identity: 60% (162 aa) FAKEFQELKNISSRQKRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ ||||||.||..|...|..|..||..||||.|..|||||||||||.||..| .|....||||||.|.|||......|.|||||||||.||||||....|.. fakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknve VVVMACREYELGKLKCKRYWPESMEETLTFAGMKISLESEEAMGDGFTVRTLAVQAGKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQDTP .|||||||.|||| ||.|||||..||.|.|. ....||.|.|. |.|..|||.|.| |....|.||||||||||.||.||..|.||....|.. .|.|.| ivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaP VLVHCSAGCGRTGTICALDYARTLLQTGRT-EELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELV ..||||||.||||||.|.||.|.||..... |||.|||.|..||.||.|.|||||||.||||||.||| lvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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| Phosphatase | Nvec_PTPN12.AA | PTPc | 22-290 | 33 | 3e-113 | 383.47 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 22-290 Range on HMM: 1-308/308 Sequence Identity: 33% (106 aa) GFAKEFQELKNISSRQKRDKAF----STNHGEKEYNR--TKNRYK-DILPYDYSRIVLPEIKGV----DGSDYINGNYIKGPTKNIMYLAAQGPLPKTVD ||..||..|.. . .. .. |....... || .||||| ||..||..|..|. ..| |||||| |||.|. .. | ..||||| |.. GFWEEFERLQRMTPWDLMS-NYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIE DFWRMMISHNIQVVVMACREYEL--------GKLKCKRYWPESMEETLTFAGMKISLESEEAMGDGFTVRTLAVQAGK----------TKHNVTQFHYTA ||||| . ......|| |.. | |. || .|||. ..|. .... ..||| . |..|.||. |. .. .. ||..|||. DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTN WPDHDVPRSATPLIELTRSFRTFVGSQ-------------------DTPVLVHCSAGCGRTGTICALDYARTLLQTGRTEELSVFDIVANLRRQRVAMVQ ||||.|| |....... | .|. .. ..|..||||||||||||.||.|.. .... ...|.|| .| || ||| WPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN-----VDIFQIVKMMRNQRPGMVQ TKEQYTLVYKAVEELVN |.||| .|... |.. TEEQYIFCYRCILEYIK |
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| Phosphatase | Nvec_PTPN12.AA | Y_phosphatase | 53-287 | 40 | 8.10000000001e-105 | 359.32 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 53-287 Range on HMM: 1-243/243 Sequence Identity: 40% (100 aa) NRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGP-TKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGK-LK-CKRYWPE-SMEE |. |||||||..||..|..|. | | ..||||| |||.|| ... | ..|||.|.|..||||| . ......|| |.. | |. | | .|||. ... NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ TLTFAGMKISLESEEAMGDGFTVRTLAVQAGKT----KHNVTQFHYTAWPDHDVPRS-ATPLIELTRSFRTFVG-SQDT--PVLVHCSAGCGRTGTICAL ..|. .... ..||| ...||||. |. .. .. ||..|||.||||.|| | ....... | .|.. . ... |..|||||||||||| ||. PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI DYARTLLQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEE |.. ..... | ..|.|| .|.|| |||| ||| .|... | DIMCQQMEHEGTV--DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.RB.PD | 26-289 | 39 | 2.6e-80 | 261.1 | In-house | 5-260 (261) | Show / Hide |
Range on Protein: 26-289 Range on HMM: 5-260/261 Sequence Identity: 39% (104 aa) EFQELKNISSRQkrdkafSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVV |..|||.....| .... |.. ||.|||.. |||||.||. | ..| ...|||| |||.| ... |.|.|||||.||||||||. .. ...| eyeelkkvgkdq------avkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiiv MACREYELGKLKCKRYWPESmEETLTFAGMKISLESEEAMgDGFTVRTLAVQAGKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQ--DTPV | . | || ||..|||.. ||. .. .|..| .|. . | ...|..... ||.|..|.|.|.|.||||.||.....|....|..|. . .. ..|. mltqlvEkgkekceeYWPad-eepvlyGdikvtllaekel-dewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPi LVHCSAGCGRTGTICALDYARTLLQTgrTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELV .|||||| ||||| ||| ... .. . || .||.||..|. .|||..|| ...... .|. vvHCsaGvGRtGtfialdrllqaiee--ndyvdvfgvvaelReeRnllvqtekqyifiheclldll |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.R_Anemone_2.PD | 25-289 | 37 | 8.8e-79 | 256.3 | In-house | 4-261 (262) | Show / Hide |
Range on Protein: 25-289 Range on HMM: 4-261/262 Sequence Identity: 37% (101 aa) KEFQELKnissrQKRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVV .|...|. ........... .. |..|||| .||.|| .|. | ...|. |||||| ||| | ... |.|.|.|||.|..|||||. | .|. eeyerls-----rseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavi VMACREYELGKLKCKRYWPESmeETLTFAGMKISLESEEAMGDgFTVRTLAVQAGKTK--HNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFV-GSQDT || .| | || |..||||.. .. .. ... |..| ..| ...|.. |. ... .| |||||.|||..|| |.. |..| |. .. |. . vmltqeeergkakvhryWPsk--gsrsygklvvelkeevelsd-yvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgag PVLVHCSAGCGRTGTICALDYartLLQTGR-TEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELV |..|||||| ||||. .|.| ||. . . . ||..| .||.|| .|||||.||...|... | . pivvhcsaGvGrtGvfiavdi---llerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.R_Sponge_2.PD | 34-290 | 38 | 5.5e-76 | 247.0 | In-house | 6-262 (262) | Show / Hide |
Range on Protein: 34-290 Range on HMM: 6-262/262 Sequence Identity: 38% (99 aa) SSRQKRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEiKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYEL . .... ||.. .... | .|||.|.||||| ||. | . .|. .||||| ... | .. |.|.||||..||.|||||..... .|| . | || eksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleen GKLKCKRYWPESMEETLTFAGMKISLESEEAMGDgFTVRTLAVQAGKT---KHNVTQFHYTAWPDHDVPRSATPLIELTRSF-RTFVGSQDTPVLVHCSA ||..|||| ..|. .. .|. |..||.. | ...|.| .. |. ...|||||..|||.|.||..||.|.|| .. |. |..... |.||.| | gkekcakYWPekvdeeveygkfkvtlkeeeklad-yiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsd GCGRTGTICALDYARTLLQTgrTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELVN |||| .||| |.. ||. ||.....|| .|. .||...|| ...|..|... gvgrtGtfialdsvlerlka--eeeidvfevlktlrtkriglvqdaaqYvfihdalleyie |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N13.PD | 24-288 | 38 | 2.1e-73 | 238.5 | In-house | 3-257 (259) | Show / Hide |
Range on Protein: 24-288 Range on HMM: 3-257/259 Sequence Identity: 38% (104 aa) AKEFQELKNISSRQKrdkafsTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGvdgsdYINGNYIKGPT--KNIMYLAAQGPLPKTVDDFWRMMISHNI |.||.||... . .. .. |.|. |..||||...|||| .|. | . | ||| ..|| | .. |.|.|||||.||.|||.|. . aeefkelrelkpldt------cevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqka QVVVMACREYELGKLKCKRYWPESMEETLTFAG-MKISLESEEAMgDGFTVRTLAVQAGKT--KHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGs .|..| | | ||.||.|||||.....|. . ....|. . . |||.||.|||. .. ..|.......||||.||.||..|... . |.. eviamvtlekekgkvkchrywPerknkklkvsnrlevellkvqkl-dgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt- QDTPVLVHCSAGCGRTGTICALDYARTLLQtgRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL . .|..|||||| ||.|.. ..| . |.. | .|. | .|| .||.|| ..||||.|| .||||. |. dagPivvhcsaGiGrsGvlitidvvlglie--rdkefdvkeivrklreqrqgvvqtkdqyifvykailev |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Choan_1.PD | 22-289 | 34 | 2.3e-72 | 235.1 | In-house | 1-261 (262) | Show / Hide |
Range on Protein: 22-289 Range on HMM: 1-261/262 Sequence Identity: 34% (94 aa) GFAKEFQELKNISSRQKRDKAfstnhgEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNI ||..|...|..| .. . ... |..||||..| || .|. ... . .|||| |...| ... |.|.|||.|.....||.|...... Gfieeyeklaeigvdntatas------kadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkv QVVVMACREYELGKLKCKRYWPESMEeTLTFAGMKISLESEEAMgDGFTVRTLAV-QAGKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQ- ...|| || | ||||| ||||. . .|... .... .|||. . |.. . . . . .|.|..||||||| || ... |.| . . . .. saivmvtreieagklkChryWPdens-elklgdvtvkslseeek-ktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkkt DTPVLVHCSAGCGRTGTICALDYARTLLQtGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELV ..|...||||| ||||| ||| . . .. ..|.|.| ..||.||..| |||| ||.||||| . . kaplvihCsaGvGrtGtyialDrlvkave-ekaealdvkavvaelrkernlmvqtlvqyefvykavldal |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.R_Anemone_1.PD | 23-288 | 37 | 8.1e-72 | 233.5 | In-house | 2-256 (258) | Show / Hide |
Range on Protein: 23-288 Range on HMM: 2-256/258 Sequence Identity: 37% (101 aa) FAKEFQELKnissrqkRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ .|.|||.|| . |..... ..|. |..||||.||...| ||.|| . .. . ||||| |... | ..|.|.||..||.|||||.. ..|. yaaefqrlk-------eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekig VVVMACREYELGKLKCKRYWPEsmeETLTFAGMKISLESEEAMGDgFTVRTLAVQAGK--TKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQD |.|| | | ||..|||. .| ... ...||...|...| ...|||... | ... |.|.|.| |||. ||. || ...| |. .. ... viVmLtnliegekkkchqYwPd---stekygelrvslrkkevfad-yiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslaga TPVLVHCSAGCGRTGTICALDyaRTLLQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL .||.|||||| ||||. ...| | | . . . .|..| ..|..| ||||||||. ...|| | rpvvvhCsaGvgRtGaflvid--amleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Choan_2.PD | 52-288 | 39 | 1.1e-70 | 229.5 | In-house | 20-264 (266) | Show / Hide |
Range on Protein: 52-288 Range on HMM: 20-264/266 Sequence Identity: 39% (95 aa) YNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKN-IMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEETL |.. |||.|||| .|..|.|.. . . ||| ||..| ... |.||.|||| |. .||||..... . .||. | |. ||.||||.. .|... rnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv TFAGMKISLES-EEAMGDGFTVRTLAVQAGKTKHNVTQFHYTAWPDHDVPRSAT------PLIELTRSFRTFVGSQD--TPVLVHCSAGCGRTGTICALD .| .||. . .|. .|. .. | ........... |.|..|||| |||.. |... | |...| .|.||||||| |||||. |.|.| kladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiD YARTLLQTgrTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL ||.. |... | |...||..|.|.||. |||.|.|||| | iavrlLee--tkkvdvlaiieelRkdRmalvqhpeqyellykavvey |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.RA.PD | 23-288 | 36 | 2.7e-69 | 225.0 | In-house | 2-264 (266) | Show / Hide |
Range on Protein: 23-288 Range on HMM: 2-264/266 Sequence Identity: 36% (97 aa) FAKEFQELKNISSRQKRdkafsTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ . .||..| .. .... . ..|| |. |||. .|||||.||..|. ..|.. ||||| .|.| . ..|||||. .||.|||||... . . leeefkkltsvkiqkek-----lrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksa VVVMACREYELGKLKCKRYWPEsmEETLTFAGMKISLESEEAMGDgFTVRTLAVQ------AGKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFV || | .. ||..|||. | ..|. ...... |. . | .||| . |. |.. |.|||.|.||. || .....| . .. . tivmltelkerkeekcaqywpd--eGlvtyGeirvevkdetvled-ytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklq GSQDT-PVLVHCSAGCGRTGTICALDYARTLLQTGRteELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL |. |||||| ||||| ..|| ... | | ||..| .|| || ||||.|||...||.. | qqsanhpivvhcsaGvGrtGtfivldavlervkaer--kldvfeavkrlrlqrpqmvqtleqyefiykvlley |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N3.PD | 39-285 | 36 | 3.7e-68 | 221.1 | In-house | 12-256 (261) | Show / Hide |
Range on Protein: 39-285 Range on HMM: 12-256/261 Sequence Identity: 36% (91 aa) RDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGvdgsDYINGNYIK--GPTKNIM--YLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELG . ..... | | .||||.|||||| |. | | . |||| ||.. |..... |.|.||||.||. |||.|. ......||| |. ||. kkpglaisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverG KLKCKRYWPEsMEETLTFAGMKISLESEeAMGDGFTVRTLAVQAGK--TKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQDTPVLVHCSAGCG .|||| .|..|.|..... .|.| . . .| | .. . .....|. |.|||||.|| ... ..|.... |. ....||.|||||| |||| . rvkChqyWPe-tedelefgefsvrceke-detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGig RTGTICALDYARTLLQtgRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAV .|. | .|.. ..|.. . ||| ..| || ..|||..||..| .|. rtGvlilletalalie--aaepvypldivrtmrdqramlvqtvsqykfvCeai |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.R_Ecdysozoa.PD | 23-287 | 33 | 3.6e-67 | 217.9 | In-house | 2-266 (269) | Show / Hide |
Range on Protein: 23-287 Range on HMM: 2-266/269 Sequence Identity: 33% (93 aa) FAKEFQELKNISSRQKrdkafSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ ...|...|.. .| ||. .||. | ||||.|| ..| |..|..|.| . ||||| ..||| .. ..|||.|.|..|||||. ..... leeeyekLearleisk-----stkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevt VVVMACREYELGKLkCKRYWPESmeETLTFAGMKISLESEEAMGDgFTVRTLAVQAGK-----TKHNVTQFHYTAWP-DHDVPRSATPLIELTRSFRTFV || . | . |..|||. .. . . . | ||| ..| .. |.| | | ...|.|..||.|. | ||..|. |..| . | . livmlsnlteknrk-cakyWpie--devqygdilvklvseekhsd-yiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrely GSQ-----DTPVLVHCSAGCGRTGTICALDYarTLLQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEE . .|..|||||| ||.|.. ||| | |. .....|..| .||.|| .|| |||. .|.|. . klnklsgsrsPivvhCsaGvgrsgifvaldl--llqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.RG.PD | 23-289 | 34 | 5.1e-67 | 217.6 | In-house | 2-263 (264) | Show / Hide |
Range on Protein: 23-289 Range on HMM: 2-263/264 Sequence Identity: 34% (92 aa) FAKEFQELKNIssrqkRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ ....|.|.... ..| ..... .|| |..|||. .|.... ||. | .. |.||.|||| .||.| .. |...||||..|..|||||.|| |.. leeqfeeiqkl-----kpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaq VVVMACREYELGKLKCKRYWPESmEETLTFAGMKISLESEEAMgDGFTVRTLAVQAGKTKH----NVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGS || | |. ....|||. .|.|.. .|. | |.| . . .|||.. ... |... .|.|.||| |||...| |... .. . .. |. iivmltdldekgrrdedvyWPkk-deplelealkvtllskekl-skytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaanke QDTPVLVHCSAGCGRTGTICALDYARTllQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELV .||.||| ||.|| .||| | . | |.... .| .| .|.|.|||. .|.|. ||| eaGPivvhdsaGvgragtyialdtllq--qlekeeavnvyqvlklirakRpglvtteEqyvfiydallelv |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N9.PD | 24-287 | 35 | 3e-66 | 215.2 | In-house | 3-272 (275) | Show / Hide |
Range on Protein: 24-287
Range on HMM: 3-272/275
Sequence Identity: 35% (97 aa)
AKEFQELKNISSRQKrdkafsTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQV
||.....| . . .. .. | .||||.|.| || .|..|..... . ||||| |...| .. ..|.||||.|||.|||||.... |.||
skeyadirnepveGt------flasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlv
VVMACREYELGKLKCKRYWPESMEETLTFAGMKISLESEEAMGDgFTVRTLAVQAG--KTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFV-----
. | | |.|||..|||.. |.. |. ...| . |.. | ..||.| .. . . .|| | ...|||. ||.||. |.... | |
ivmttrvvergrlkcgqywpleeessaefgdlsvsnveveveed-ykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavk
--G------SQDTPVLVHCSAGCGRTGTICALDYARTLLQTgrTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEE
.. |..|||||| ||||| ..||.. . |.. .. . |.. | .|| || ..||.|||.. |.|| |
elgdeskghlsgPPivvhcsaGiGrtGtfitldiclarlee--vgtvdvvetvkllrtqrafsiqtpeqyefcylavle
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N5_RR.PD | 52-286 | 36 | 3.4e-65 | 211.6 | In-house | 22-261 (265) | Show / Hide |
Range on Protein: 52-286 Range on HMM: 22-261/265 Sequence Identity: 36% (89 aa) YNRTKNRYKDILPYDYSRIVLPE-IKGVDGSDYINGNYIKGPTKN-IMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEE- . ||||||.||| . ||..| . . |.||| |||||. .. .|.|.|||||.|..|||||. ...||.|| . | . ||..|.|.... gsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedye -TLTFAGMKISLESEeAMGDGFTVRTLAVQAGKT-KHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVG---SQDTPVLVHCSAGCGRTGTICALDYA . .. ...| |. ....||.| .. . ...|. . ||.||||..|.....|..| . .. . .||.|||||| |||| | . | iserygdveikveei-verndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisia RTLLQtgRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVE |. ... . |. ||.||| .| ||||.||| |...|. vrqlr--eeivvdvlkivcnlrldrGGmvqtseqyelihralc |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.RK.PD | 23-288 | 33 | 2.3e-63 | 205.4 | In-house | 2-265 (267) | Show / Hide |
Range on Protein: 23-288 Range on HMM: 2-265/267 Sequence Identity: 33% (90 aa) FAKEFQELKNISSRQKRDkafSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVdGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ . .||. |. .. . . . . . . |. ||.|||..|||.|| |...| ..| |||||...| . .. ....||||..|| ||||...| . lkeefetlnsvtpelqse---dcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydenca VVVMACRE-YELGKLKCKRYWPESMEEtlTFAGMKISLESEEAMGDgFTVRTLAVQA----GKTKHNVTQFHYTAWPDH-DVPRSATPLIELTRSFRTFV || | |..|| .|||| | .. .|. | . |. | . ||...|. . .. | ||....||.. ||| |..|..| | . sivmlteldvevgrvkClkyWPedtev--rygdikvelveaeldad-lvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksq GS-QDTPVLVHCSAGCGRTGTICALDYARTLLQTGRTeeLSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL .. ...|||.||.||.|| .|.| .... .. . || .| .|| ..| ||.|.|||..|| .. | eeeeeGrivvhClaGaGrsGtfiaidivlemieregv--vdvfnavktlrnrkvnmveteeqykfvydvilea |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.RC.PD | 24-287 | 34 | 8.4e-58 | 187.4 | In-house | 3-285 (288) | Show / Hide |
Range on Protein: 24-287 Range on HMM: 3-285/288 Sequence Identity: 34% (100 aa) AKEFQELKNISSRqkrdkaFSTNHGEKEYNRTKNRYKDILPYDYSRIVL-------------------PEIKGVDGSDYINGNYIKGPTKNIMYLAAQGP |||.| .. |. .. . ..||.|..|||| |.||||| |. | .|.. .||.||| .|.. | .|.|||||| eaefqrlpsvrsk------rtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGp LPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWpesMEETLTFAGMKISLESEEAMGDgFTVRTLAVQAGKTKH--NVTQFHYTAWPDHDVPRSA .||||||||. . ..|.|| . | . || .|| | . .. ... |. .. | ...| | .. | | .|||. ||.|.....| lketvddfwrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssd-yilrklelvnkkrkdsrevtqiqytswsveqlpeep TPLIEL----------TRSFRTFVGSQDTPVLVHCSAGCGRTGTICALDyarTLLQTGRTEE-LSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEE |..| || .| . ||.||||..| .|||. .||. .||.. .|| . ||..| .||..| ||...||| |.|... | kellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiall---allesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Nematode_1.PD | 24-284 | 34 | 3.9e-57 | 185.1 | In-house | 3-259 (265) | Show / Hide |
Range on Protein: 24-284 Range on HMM: 3-259/265 Sequence Identity: 34% (92 aa) AKEFQELKNISSRQkRDKAFSTNHGEKeynrtKNRYKDILPYDYSRIVLPeiKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQV .||..||. .. . . |||.... .. ||||||. | .|..| .. |||| ||. ||. .. ||.|| ||..||| |.. .... . rdefralkkfndee-kvkafkeaqead-----knrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekvea VVMACREYELGKLKCKRYWPESMEETLTFAGM--KISLESEEAMG------DGFTVRTLAVQA-GKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRT || |. | || ||. |.| ...|.|.| ||..|.. .. . .| .| |. |.....||....| |||. || .|| . |. ivmlckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrg fvgsQDTPVLVHCSAGCGRTGTICALDYARTLLQTGRTEElSVFDIVANLRRQRVAMVQTKEQYTLVYKA . .|..|||||| |||||| |..| | |.. | . ..| ..||| .|| || |.. ----skgPivvhCsaGiGrtGtivaieyildkllegkqie-dmeklvkkireqrnysiqtdaqylfvhrv |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.RN.PD | 42-290 | 36 | 5.4e-57 | 184.6 | In-house | 16-264 (264) | Show / Hide |
Range on Protein: 42-290 Range on HMM: 16-264/264 Sequence Identity: 36% (91 aa) AFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKG-PTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKR ... ...| | .|||.|..|||| ||. | | . ||||| | .. .|.|.||||..|. |||.|. . . |.|. .| | |.||||||. pstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckr YWPESMEETltFAGMKISLESEEAMGDGFTVRTLAVQAGKTK--HNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQDTPVLVHCSAGCGRTGTIC .|. . .. | || | . ||.. .. .|. |||||. .||...|| || .|.|. | . .|..||||.|.||||. ...| ywpdeGsev--yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyi ALDYARTLLQTGrTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEELVN . |. | |. . . || || .|.||.|. ....|| | || lidlvlerllkG-vkeidiaatlehlrdqrpglvktkdqfefaltavaeevn |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N20.PD | 44-288 | 40 | 2.1e-55 | 179.6 | In-house | 17-255 (257) | Show / Hide |
Range on Protein: 44-288
Range on HMM: 17-255/257
Sequence Identity: 40% (99 aa)
STNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKgvdgsDYINGNYIK--GPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRY
| |.. || ||||.|||||| .|. | . | |||| .||. .. .|.|.|||| |.||||.|.. | .|. | || | |.|| .|||
efnsgnqpsnreknryrdilpydstrvplgksk-----dyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhy
WPESMEETLTFAGMKISLESEEAMgDGFTVRTLAV--QAGKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTfvGSQDTPVLVHCSAGCGRTGTICA
|... | . ... || . . . | .| . | .. | |.| |...| |||| | || .|. | | |..|||||| |||| . ..|
wpislkkplelkhfrvflenyqil-qyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryark--shltgpmvvhcsagigrtgvflc
LDYARTLLqtGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL
. . . ..||||..| || |||||||| ..| | |.
vdvvfcai--vkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlev
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N1.PD | 30-285 | 33 | 7.4e-53 | 171.3 | In-house | 5-263 (268) | Show / Hide |
Range on Protein: 30-285 Range on HMM: 5-263/268 Sequence Identity: 33% (86 aa) LKNISSRQKRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGvdgsDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACR . . ... ..|...|.. ... ||..|||.|. |||.|||.| . . |||| . .. . . |. .|||||.|.| ||.|. .| .|.| . illeidkeskekeletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnk EYELGKLKCKRYWPESMEE-TLTFAG--MKISLESEEAMgDGFTVRTLAVQAGKT--KHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTF--VGSQDTP | ...|| |||. .|| .|.. .|. | ||| . |.||.| .. .| .....|||| ||| ||.| . ....|. . |. .|. .|| vvEknqikCaqywpqeeeeaellleetklkvkliseerk-syflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgp VLVHCSAGCGRTGTICALDYARTLLQ-TGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAV ||| ||.||.. .| ... || .. . . . . .||..|| ..|| .| | |. avihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiai |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N14.PD | 27-285 | 34 | 3.1e-52 | 169.0 | In-house | 3-270 (275) | Show / Hide |
Range on Protein: 27-285
Range on HMM: 3-270/275
Sequence Identity: 34% (94 aa)
FQELKNISSRQKrDKAFSTnhGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVdGSDYINGNYIKGP--TKNIMYLAAQGPLPKTVDDFWRMMISHNIQVV
|.| .|. ... | .|| .. . | |||.||.|||. .|. | | ..||| || . .|. |..|||||..|| |||.|....|..||
fteyeripkkre-dallst--aklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqli
VMACREYELGKLKCKRYWPES--MEETLTFAGMKISLESEEAMGDgFTVRTLAVQ--AGKTKHNVTQFHYTAWPDHDVPRSATPLIELTR---SFRTFVG
.| | || |. .|.|.. ..|..| |.. . | . .. ..| .. | . .| . || ||||.||. ..... . | | . |
vmlteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsds-vittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktn
S-------QDTPVLVHCSAGCGRTGTICALDYARTLLQTGrtEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAV
.. ||||||||| |||| . | . |... ||. . ..| ||.|| .||| ||..|||..
sevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehn--eeidikkvlarLrkqrmllvqtlaqykfvykvl
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Nematode_4.PD | 49-285 | 33 | 1.1e-49 | 160.7 | In-house | 22-259 (264) | Show / Hide |
Range on Protein: 49-285 Range on HMM: 22-259/264 Sequence Identity: 33% (80 aa) EKEYNRTKNRYKDILPYDYSRIVLPEIKgvDGSDYINGNYIKGPtKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEE | | ||||.||| | .|.|| . . ||| .... | . |...||||..|..||| |. |.|||| | || ||.||.|| |.. . aseknsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksek TLTFAGMKISLESEEAM-GDGFTVRTLAVQAGK------TKH-NVTQFHYTAWPDHDVPRSATPLIELTRSFRTfvGSQDTPVLVHCSAGCGRTGTICAL | .| | .. . . ...| | . . ... | .... |.|. | |.|.|.|. . ....|. |||||| ||| |. .|||. vvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGi DYARTLLQtgRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAV .. . |. | ||| .|| |. ||.. |. .. . dyatirir--enseievldivrelramrlkavqshlqflfllvvl |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N23.PD | 79-286 | 35 | 7.7e-48 | 154.8 | In-house | 129-346 (350) | Show / Hide |
Range on Protein: 79-286 Range on HMM: 129-346/350 Sequence Identity: 35% (76 aa) DGSDYINGNYIKGPTKN-IMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEETLTFAGMKISLESEEAMgDGFTVRTLAVQ .|||| |.| | ..|.|||...|. ||| |. . .|.|| .| | .||||..|||. .|| .| ...||.|.. .|.|.| .| qqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrss-egwiervlhlq AG--KTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFV---------GSQDTPVLVHCSAGCGRTGTICALDYARTLLQTGRtEELSVFDIVANLRR .|...|...|.|.|... || | |... .| | . |...||||| |||||.| . | |..|.. . ..| .||.|| ||| hndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagn-giiniprvvrrlrq QRVAMVQTKEQYTLVYKAVE .|... .|.|| qRkymvqkkvilkklyeavl |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.R_Nematode_2.PD | 50-280 | 29 | 1.9e-46 | 150.0 | In-house | 26-251 (261) | Show / Hide |
Range on Protein: 50-280 Range on HMM: 26-251/261 Sequence Identity: 29% (66 aa) KEYNRTKNRYKDILPYDYSRIVLpEIKGVdGSDyINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEET . .. |.||.|. . .... ..| .. | |.. .... ..|.|||| |..||| |.| .... .|| |. || ||..|.| .....|. aylpkdkhRypdvPCkpetavev-ivdgk-rvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqk LTFAGMKISLESEEAM-GDGFTVRTLAVQAGKT---KHNVTQFHYTAWPDHDVPRSATPLIELTRSFRtfvgSQDTPVLVHCSAGCGRTGTICALDYART . ..| |.| . | ..||| |. .. ..|| . |. |||..||.| . | || ... |..|||||| |||... . .| ... .| ldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvk----ksekPivvhCsaGiGRtmafigteylar LLQTGRTeeLSVFDIVANLRRQRVAMVQTKEQYTL ... . ...|| .| .||..|. eveadpt--ieltealkelrehRwkgiqtesqlyw |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Nematode_5.PD | 24-286 | 27 | 9.7e-46 | 147.6 | In-house | 3-254 (258) | Show / Hide |
Range on Protein: 24-286 Range on HMM: 3-254/258 Sequence Identity: 27% (73 aa) AKEFQELKNISSRQKRDKAFSTNHgekeynrTKNRYKDILPYDYSRIvlpeIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQV .||..|.... ... ||| | .|||.||. .| .|. ... . ..||| ..|| . . ... .| |||.|. |||||.....|. | ktefeklaslkpnketckafeknl-------kknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekits VVMACREYELGKLKCkRYWPESMEETLTFAGMKISLESEEAMGD---GFTVRTLAVQAGKTkHNVTQFHYTAWPDHDVPRSATPLIE-LTRSFRTFVGSQ |..... || . .. ..|..... |.. .| | | . | .|| .|. . . . ..|.| |... || . ...|. .. ....| vvllvedeelketav-sffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgk DTPVLVHCSAGCGRTGTICALDYARTLLQTGrtEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVE |.|....|.||.||. .|..| . |..| .|. . .|. ..| ||. .|.. ||. ||.|| napvvvvsdlGlgRagtflllsvaieqlnng--kepnideilkkirsqRpgavesliqyasvyaavl |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Nematode_6.PD | 24-288 | 29 | 1.2e-42 | 137.7 | In-house | 3-251 (253) | Show / Hide |
Range on Protein: 24-288 Range on HMM: 3-251/253 Sequence Identity: 29% (79 aa) AKEFQELKNISSRQKrDKAFSTnhgekeyNRTKNRYKDILPYDYSRIVLPEikgvDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQV ||... |..| .. .|| . ....|||..| .| .|..| . | || |..| ||. .. .|.|| .|...||.|..| .. . kkeykdspneasese-ataflk-------fkdrnrytniqCcdagrlklad----dedfyihanlvkistkprrlictqaplegtieefwkmilssgvey VVMACREYELGKLKCKRYWPESMEETLTFAGMKISLESEEAMGDGFTVRTLA--VQAGKTKHNVTQFHYTAWPDHDVPRSATPLIELTrsfrTFVGSQDT || | | || |. .| .. . .. .. . .. .. | .||.| |.||. . | .|. .|||| || | . . | . | .. | ivmlcelvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrll----svvkkdkk PVLVHCSAGCGRTGTICALDYARTLLQTgrTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVEEL ..|||||| |||||. . . |.. .. .| |....||..|. |||. || ... | | PivvhCsaGvGrtGtlaliliilealrl--pdfqgvkdllvklreerfravqtevqylyalrcvley |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.R_Nematode_3.PD | 44-282 | 25 | 8.9e-41 | 131.5 | In-house | 21-259 (267) | Show / Hide |
Range on Protein: 44-282 Range on HMM: 21-259/267 Sequence Identity: 25% (63 aa) StnhgekeYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLaAQGPL--------PKTVDDFWRMMISHNIQVVVMACREYE--- | . ...|..... . .|.|| . . .|.|. |... | .. . | .|.|. .|.. || |. .. ..||| | .| s-------kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglklIl-tqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedg LGKLKCKRYWPESMEETLTFAGMKI-SLESEEAMGDGFTVRTLAVQAG-KTKHNVTQFHYTAWPDHDVPRSATPLIELTRsfrtFVGSQDTPVLVHCSAG .. || .|.||. .. |.| |... . .. . ... ||| |. | .. || .|..|... .| .. ...|| . || . |||.||||.| eeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelik----fveksktpvvVHCsdG CGRTGTICALDYARTLLQTGRTeELSVFDIVANLRRQRVAMVQTKEQYTLVY .|..|. | ... |. . . .|.. ... .||.|| .||..... | isRsatlaaielgyqliikskg-kldllslikelrkqRagaiqtelelafvi |
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| Phosphatase | Nvec_PTPN12.AA | PTPc_motif | 184-287 | 39 | 8.6e-37 | 129.46 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 184-287 Range on HMM: 1-92/92 Sequence Identity: 39% (43 aa) NVTQFHYTAWPDH-----DVPRSATPLIELTRSFRTFVGSQDTPVLVHCSAGCGRTGTICALDYARTLLQTGRTEELSVFDIVANLRRQRVAMVQTKEQY |...|||.|||| || ...|. |..| |..||||||||||||.||.|.. . ...|..| .| || ||||.||| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ--------VDIFQTVKEMRKQRPGMVQTEEQY TLVYKAVEE .|... | IFCYRCILE |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Nematode_egg.PD | 23-286 | 24 | 2.5e-32 | 103.9 | In-house | 2-253 (257) | Show / Hide |
Range on Protein: 23-286 Range on HMM: 2-253/257 Sequence Identity: 24% (66 aa) FAKEFQELKNISsrqkrdKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQ . ..|. |.. . | .. .. ...| | | . ..||. | .| |.| |..|| .. || || ||.|||||. ..| lerrfeilersv------deislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvq VVVMACREYELgkLKCKRYWPESMEETLTF--AGMKIS-LESEEAMGDGFTVRTLAVqAGKTKHNVTQFHYTaWPDHDVPRSATPLiELTRSFRtfvgSQ .|| | .|. ||| . .|.| . ...| |. ... |.| | . | .. |. . . . .|| .. | | yivmltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl-vGgddeelflehwq-gdvnylsdvyspl-rvlrklr----nl DTPVLVHCSAGCGRTGTICALDYARTLLQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAVE .||.|.. |. ...|. |.. | | | . | | ||..| |.. .| .||. | skpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Fungi_PTP1.PD | 33-150 | 33 | 8.1e-28 | 88.9 | In-house | 29-156 (343) | Show / Hide |
Range on Protein: 33-150 Range on HMM: 29-156/343 Sequence Identity: 33% (43 aa) ISSRQKRDKAFSTnhGEKeyNRTKNRYKDILPYDYSRIVLP--------EIKGVDGSDYINGNYIKGP----TK--NIMYLAAQGPLPKTVDDFWRMMIS |. . | .|. | . .|||||.||||. ||. |. . . ..|||| ||.| . . |.|.|.|||.|||||..... dsdsesddviiss--Gve--lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvill HNIQVVVMACREYELGKLKCKRYWPESMEETL ...|... . ||. || |||.| . nkvkvilsltsdvelnlekcyrYWqegsyddi |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Fungi_PTP1.PD | 182-286 | 29 | 2e-19 | 61.3 | In-house | 212-339 (343) | Show / Hide |
Range on Protein: 182-286 Range on HMM: 212-339/343 Sequence Identity: 29% (37 aa) KHNVTQFHYTAWPDH---DVPRSATPLIE-------LTRSFRTFVGSQDTPVLVHCSAGCGRTGTICALDYART---LLQ--TGRTEEL--------SVF ..| |... |.| |.| . .| . . .. .|.|||||||.|||||...||. |. |. ..| .. | pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlis DIVANLRRQRVAMVQTKEQYTLVYKAVE | .||.||. |||...|. .|.|. iivnelrkqrismvqnldqfifiYeall |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.N_Nematode_eak.PD | 39-200 | 18 | 7.4e-14 | 43.2 | In-house | 12-171 (281) | Show / Hide |
Range on Protein: 39-200 Range on HMM: 12-171/281 Sequence Identity: 18% (29 aa) RDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKgVDGSDYINGNYIKGPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKC .. | . ... . .|| .|.|.|. . | . . ||| .. . |. . . . | ||.|.. ..|. . |.. | .|.| yqrllsirvtarleavnrnrvvkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleks KRYWPESMeETLTFAGMKISLESEEAMGDGFTVRTLAVQAGKTKHNVTQFHYTAWPDHDVPR . | | . ... . . . .| | .. | |.| ... | . ..|. dkyfpdkt-evlkyGildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpk |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.DSP23.PD | 217-282 | 34 | 2.1e-10 | 32.4 | In-house | 63-123 (128) | Show / Hide |
Range on Protein: 217-282 Range on HMM: 63-123/128 Sequence Identity: 34% (23 aa) GSQDTPVLVHCSAGCGRTGTICALDyartLLqtgRTEELSVFDIVANLRRQRVAMVQTKEQYTLV--Y .. .| ||| |.|||||. | |. ..|.|. | .|..|..| ..|.|| .| | ekkeeavgvhcalGlGrtGtllacy----lv---keeglaaddaiaevrkrrkGsietveqekavkdy |
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| Phosphatase | Nvec_PTPN12.AA | Family.DSP.PD | 119-239 | 13 | 3e-10 | 31.5 | In-house | 131-204 (387) | Show / Hide |
Range on Protein: 119-239 Range on HMM: 131-204/387 Sequence Identity: 13% (17 aa) HNIQVVVMACreyelgklkckrywpesmeetltfagmkisleseeamgdgftvrtlavqAGKTK---HNVTQFHYTAWPDHDVPRSATplIeLTRSFRtF ......| .. .|.. . ... ...|| .| . . ...... | lgvtkivnlt-------------------------------------------------ddkpqftkelgikylripidDhnapplen--l-fekaid-f VGS---QDTPVLVHCSAGCGRTGTICA . . . ||||| || ||.||... ieegndskgvVlVHCkaGkgRsgtlii |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.PTPDC1.PD | 184-282 | 24 | 3.1e-09 | 28.2 | In-house | 133-221 (229) | Show / Hide |
Range on Protein: 184-282 Range on HMM: 133-221/229 Sequence Identity: 24% (24 aa) NVTQFHYTAWPDHDVPrSATPLIELTRSFRTFVgsQDTPVLVHCSAGCGRTGTICAldyaRTLLQTgrtEELSVFDIVANLRRQRVAMVQTKEQYTLVY . |. ...|..|. | . .... . . .. . ||| || |||| . | |. . ..|. . . .| .| .||.|| || qgiyfynfglkDygva-sleriLdivkvvdfal--eegkiavHCHAGlGRtGvlia----cylvya---krltaeeaiklvrskrpksiqtreqvelve |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.TPIP.PD | 194-259 | 34 | 1.3e-07 | 23.0 | In-house | 11-76 (245) | Show / Hide |
Range on Protein: 194-259 Range on HMM: 11-76/245 Sequence Identity: 34% (23 aa) PDHDVPRSaTPLIELTRSFRTFVGSQDTP-VLVHCSAGCGRTGT-ICALDYARTLLQTGRtEELSVFD ||.||. |. .|. .. .. | .|| | ||||| .||| | ...| . | | | ddhnvPtl-eelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltae-esldyfg |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.CDC14.PD | 202-281 | 27 | 4.7e-06 | 18.0 | In-house | 180-252 (258) | Show / Hide |
Range on Protein: 202-281 Range on HMM: 180-252/258 Sequence Identity: 27% (22 aa) ATPLIELTRSFRTFVGSQDTPVLVHCSAGCGRTGTICALdYartLLQTgrtEELSVFDIVANLRRQRVAMVQTKEQYTLV ..| .. ..| . . . . . ||| || |||||. . | |... ... ...| || | .| .. | || tvPsdailkkfleitekaeGaiavhCkaGLGrtgtligc-y---likh---yrftaaetiawlriarPGsvigpqqtylv |
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| Phosphatase | Nvec_PTPN12.AA | Subfamily.PTEN.PD | 195-259 | 29 | 5.9e-06 | 17.4 | In-house | 69-133 (305) | Show / Hide |
Range on Protein: 195-259 Range on HMM: 69-133/305 Sequence Identity: 29% (20 aa) DHDVPRsATPLIELTRSFRTFVGSQDTP-VLVHCSAGCGRTGTI-CALDYARTLLQtGRTEELSVFD || |. | |. .. .. .... | ||| || ||||.. || . .. . | |...| Dhnppt-leLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikk-sadealaiyd |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Nvec_PTPN12.AA | Protein | None | 352 | None | Fasta, JSON |
| Nvec_PTPN12.NA | RNA | None | 1056 | None | Fasta, JSON |
| Nvec_PTPN12.AA.PD_22-290 | Protein Phosphatase Domain | None | 269 | None | Fasta, JSON |