• Phosphatome.Net

Gene Nvec_PTPN13

Nvec_PTPN13
Species: N.vectensis
Alias: Nvec_PTPN13, Nvec_114126
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N13
Protein domain

Protein domains of Nvec_PTPN13.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Nvec_PTPN13.AA Subfamily.N13.PD 31-291 65 1.5e-141 462.0 In-house 1-259 (259) Show / Hide 
Range on Protein: 31-291
Range on HMM: 1-259/259
Sequence Identity: 65% (170 aa)

MPEEEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSSGedYINANHIRVLVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVT
.|.||||.|||.||.| |..||...|.|||||||||||..|||.|....|  ||||..|.| |..|.|.|||.|||||.|.||||||.||| .||.||||
qPaeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt

LDKEGGKVKCHRYWPDNTNQPLKLGGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLATSQAPVVVHC
|.||.||||||||||...|..||. .|.||.|||....|.||.|..|||...||.|.|.||||||||||||||.|..|.|||||..|.|.|...|.||||
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhc

SAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVLK
||||||.|.||..||.|||.||||.||.....|.|||||||..||||||||.|||.|||||
saGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
Phosphatase Nvec_PTPN13.AA PTPc 31-291 32 3.1e-111 376.76 SMART 1-308 (308) Show / Hide 
Range on Protein: 31-291
Range on HMM: 1-308/308
Sequence Identity: 32% (103 aa)

MPEEEFKDLREIKPTD---------GCDSGKNQANT--DKNRYR-NVLPYEATRVRLSGSSGE-------DYINANHIRVLVDDDTYHYIATQGPLPNTT
. .|||..|.. .|.|          |.... ..|   |||||. ....|. |||.|.   ||       ||||||.|..   . .  ||.||||||.| 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI

KDFWQMIWEQGVEVVAMVTLDKEG--------GKVKCHRYWPDNTNQPLKLGGRFEVSLLKQTNYD-SFVQRDIAVKHLQS--------GKSIEIAHLNF
 |||.|.|.|......| . . |.        |..|||.||||.   |.. | ...| ... .... ... |.. |.. .         ... .. |...
EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYG-HITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHY

VKWPDHGVPRSPVEMVQFVAYMRSLATSQ--------------------APVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQ
  ||||||| ||  . .|. ..|.   ..                    .|.|||||||.||||...|.|... ..|.   .|| |... .|.|| ||.|
TNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQ

TKDQYIFCYKACLEVLK
|..||||||.. ||..|
TEEQYIFCYRCILEYIK
Phosphatase Nvec_PTPN13.AA Y_phosphatase 56-288 38 5e-106 363.35 Pfam 1-243 (243) Show / Hide 
Range on Protein: 56-288
Range on HMM: 1-243/243
Sequence Identity: 38% (96 aa)

NTDKNRYRNVLPYEATRVRLS---GSSGEDYINANHIRVLVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGK-VK-CHRYWPD-NTN
| .||||.....|. |||.|.   |  . ||||||.|.. ..     ||.||||.|.| .|||.|.|.|......|.. . |.|. .| ||.||||   .
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG

QPLKLGGRFEVSLLKQTNYDSFVQRDIAVKHLQS--GKSIEIAHLNFVKWPDHGVPRS-PVEMVQFVAYMRSLAT-----SQAPVVVHCSAGIGRTGALI
||.. | .|.| . . . .. .. |.  |.. ..  ... .. |. .  ||||||| | |  |..|. ..|.  .     . .|.|||||||.||||...
QPMTYG-DFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGC-PPIVVHCSAGCGRTGTFC

AVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
|.|... .||... .|| |... .|.|| ||.|| .||||||.. ||
AIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Nvec_PTPN13.AA Subfamily.N3.PD 36-289 42 1.5e-86 281.5 In-house 6-259 (261) Show / Hide 
Range on Protein: 36-289
Range on HMM: 6-259/261
Sequence Identity: 42% (109 aa)

FKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSSGeDYINANHIRVLVDDDT--YHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDK
|. |   ||   ..  .  .| .|||||..|||.||||.|. |.  ||||||.. . ..  .   .||||||||..|.||||||.||| ....|.|   |
feelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlv

EGGKVKCHRYWPDnTNQPLKLGgRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLA-TSQAPVVVHCSA
 |.||||.|||. |.. |..| .|.| . |. .  |.| |.. .|. .. .. .| .| .. ||||||| .. ....||  .|.|... |||||||||||
erGrvkChqyWPe-tedelefg-efsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsa

GIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEV
||| ||....|| |.|. .|. . . .| .|.||. ..||..|| |  .| |..   
GigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka
Phosphatase Nvec_PTPN13.AA Subfamily.RB.PD 33-290 36 1.9e-81 264.9 In-house 3-260 (261) Show / Hide 
Range on Protein: 33-290
Range on HMM: 3-260/261
Sequence Identity: 36% (97 aa)

EEEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRL---SGSSGEDYINANHIRVLVddDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMV
.||...|.... .. ... ....|..|||..|.|||...||.|   . .|..||||||.|         .|||||||||.|..|||.|.||. .... |.
seeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgyn--spreyiatqGPlpetvddfWrmvwekkssiivml

TLDKEGGKVKCHRYWPDNTNQplKLGGRFEVSLLKQTNYDSFVQRDIAVKHlqSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLATSQ---APV
|   |.||.||..|||.....   | |  .|.||.....|..| |......    .. .. ...|. |||||||...  ...||  .|. ....   .|.
tqlvEkgkekceeYWPadeep--vlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPi

VVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
|||||||.||||. ||.|  |  .|..   |.  .. .|||.|. ..||..|||| ... |..|
vvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll
Phosphatase Nvec_PTPN13.AA Subfamily.N_Choan_1.PD 34-290 39 7.1e-80 259.7 In-house 4-261 (262) Show / Hide 
Range on Protein: 34-290
Range on HMM: 4-261/262
Sequence Identity: 39% (103 aa)

EEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLS---GSSGEDYINANHIRVLVDDDtyHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVT
||...|.||   . . . |...|. ||||.|.  |.||||...    ..  ||||||..  . ..   .|||||||.|.. ..||||.||| |....|||
eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgek--eyiatqgPvPaslvsfWqmvweqkvsaivmvt

LDKEGGKVKCHRYWPDNTnQPLKLGgRFEVSLLKQTNYDSFVQRDIAVkHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLATSQA--PVVV
 . |.||.||||||||.. . ||||  . |. |....  ....| . . . .||.. |...|....|||||||.. |...| . .... ...   |.|.|
reieagklkChryWPden-selklg-dvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvi

HCSAGIGRTGALIAVDVALGLMERDKPF-DINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
||||.||||. ||.| ..  .|....  |.......||..|. |.||  || | |||.|..| 
hCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal
Phosphatase Nvec_PTPN13.AA Subfamily.R_Anemone_2.PD 34-290 40 2e-78 255.1 In-house 4-261 (262) Show / Hide 
Range on Protein: 34-290
Range on HMM: 4-261/262
Sequence Identity: 40% (106 aa)

EEFKDL-REIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLS---GSSGEDYINANHIRVLVDDDTyhYIATQGPLPNTTKDFWQMIWEQGVEVVAMV
||.. | |. . .  ..|  ...|  |||| |.|.|. |||.|.   |. | ||||||.|     . .  |||||.|||.| .|||.|.|||.  |. |.
eeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkka--yiatqaPlpetiedfWrmvWeqnsavivml

TLDKEGGKVKCHRYWPDNTNQPLklgGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLA--TSQAPVV
|  .| ||.|.|||||..  . .   |.  | | ........| | . ||. .. .. ..   .. .|||.||| |.......|  ...    ... |.|
tqeeergkakvhryWPskgsrsy---gklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpiv

VHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
||||||.||||  ||||. |  .. ..  |. ||.. |||||. |.||||||.|.|.. || |
vhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase Nvec_PTPN13.AA Subfamily.N12.PD 48-290 41 2.4e-75 244.7 In-house 24-269 (270) Show / Hide 
Range on Protein: 48-290
Range on HMM: 24-269/270
Sequence Identity: 41% (104 aa)

CDSGKNQANTDKNRYRNVLPYEATRVRLSGS---SGEDYINANHIRVLvdDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYW
..|... |. ||||...|||. .|| ||      |.||||||.|.    ... .|||.|||||.| .|||.||||. ||.| |.    | ||||.||||.
teagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgv--egkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryW

PDNTNQPLKLgGRFEVSLLKQTNYD-SFVQRDIAVKHLqsGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLATSQ-APVVVHCSAGIGRTGALIA
.....|.  |.|||.| .. . |  |. | ..|..   ..| ..  ... .|||||||.|. ....... .|.| .|. ||.|||||||.||||..||.|
peegeeelef-gefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiia

VDVALGLMERDKP---FDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
 .  |....|    .|. . . .||.||. ..|||.|| . ||| .|..  
idyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
Phosphatase Nvec_PTPN13.AA Subfamily.N14.PD 35-291 36 2.8e-74 241.3 In-house 5-275 (275) Show / Hide 
Range on Protein: 35-291
Range on HMM: 5-275/275
Sequence Identity: 36% (99 aa)

EFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSS--GEDYINANHIRVLVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLD
|.  . . .    ....|.. |..|||...||||| .||.|| .    ..|||| .|.| |   ...||..||||..| .|||||.|||||....|.| .
eyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee

KEGGKVKCHRYWPDNTNQPLKL-GGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLAT----------
.|.|| |...|.|.....  ..  |.|.|.   ... ||.. . . .||| |..  .. || .. |||||||. . ....|.  ..|.            
eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk

-SQAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVLK
 |. ||.||||||.|||| || .|. .  .| ..  ||..... ||.||. ..||  || | ||. .. ||
eskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikylk
Phosphatase Nvec_PTPN13.AA Subfamily.N9.PD 34-288 39 9.6e-73 236.6 In-house 4-272 (275) Show / Hide 
Range on Protein: 34-288
Range on HMM: 4-272/275
Sequence Identity: 39% (100 aa)

EEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSS---GEDYINANHIRVLVDDDTyhYIATQGPLPNTTKDFWQMIWEQGVEVVAMVT
.|..|.|. ...   .  | .|| .|||| .|| |. ||| |.  .     ||||||..      ..  .|||||||..|..|||.|.||| ||. |.| 
keyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkka--fiatqGplkktvsdfwrmvweqevlvivmtt

LDKEGGKVKCHRYWPDNTNQPLKLgGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLA----------
  | |..|| .|||.....  .  | ..|| ... ... ...| . .|. ....| .. |  |. |||.|||.|  ......  .|..|. |.|||||||
rvvergrlkcgqywpleeessaef-gdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

----TSQAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
|||||..|..|..|  .|.    |. .|.. ||.||  .|||..|| |||.| ||                 
skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase Nvec_PTPN13.AA Subfamily.R_Sponge_2.PD 46-290 32 7.2e-72 233.6 In-house 15-261 (262) Show / Hide 
Range on Protein: 46-290
Range on HMM: 15-261/262
Sequence Identity: 32% (80 aa)

DGCDSGKNQANTDKNRYRNVLPYEATRVRLSG--SSGEDYINANHIRVLVDDDTyhYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRY
.. .|.. |. |||....|||. .||||.   |.. |||||... ..   ..  ||||||||..| .||| |.||. |. . |.|  .| || ||..|||
fslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrka--yiatqgPlketveDfWRmvweykvstivmltnleengkekcakY

WPDNTNQPLKLGGRfEVSLLKQTNYDSFVQRDIAVKHLQS-GKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRS--LATSQAPVVVHCSAGIGRTGAL
.....  ..|   .| | .....  .. |.. ... .| ... .... .||.||.|.||..   ........     . . ...|.||.|.||||. ||.
WPekvdeeveygkf-kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtf

IAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
|. |  .. ..  |. .....|| .| |..|...|| |...| ||..   
ialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi
Phosphatase Nvec_PTPN13.AA Subfamily.N20.PD 47-291 45 1.3e-71 232.8 In-house 17-257 (257) Show / Hide 
Range on Protein: 47-291
Range on HMM: 17-257/257
Sequence Identity: 45% (110 aa)

GCDSGKNQANTDKNRYRNVLPYEATRVRLSGSsgEDYINANHIRVLVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPD
.||.. .| .|||||..|||..||| |  |  .|||||..||..   . | |||||||| .|  |||||. |.  .|.||.| . ||| .||..||| . 
efnsgnqpsnreknryrdilpydstrvplgks--kdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpi

NTNQPLKLGgRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSlATSQAPVVVHCSAGIGRTGALIAVDVA
..||.|  .| | | .    . |. | . |    .| |  . .|.| |||||| | |   ..... | |  .    |.|||||||||||| ...||| . 
slkkplelk-hfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryark-shltgpmvvhcsagigrtgvflcvdvv

LGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVLK
 . ..  |.| . . ..|||| ||.|||.|| |||   ||||.  
fcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevlr
Phosphatase Nvec_PTPN13.AA Subfamily.R_Anemone_1.PD 34-290 36 6.5e-71 230.6 In-house 4-257 (258) Show / Hide 
Range on Protein: 34-290
Range on HMM: 4-257/258
Sequence Identity: 36% (95 aa)

EEFKDLREIKpTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSG---SSGEDYINANHIRVLvdDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVT
.||. |.||| ..  .......|..|||| ...... .|| |.     .  ||||| ..|.   |.|  .||||.||..|..|||.|.|.. . |. |.|
aefqrlkeik-eeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylras--dktrafiatqapleetvedFWrmvwqekigviVmLt

LDKEGGKVKCHRYWPDNTNQplklGGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSL-ATSQAPVVVH
  .|| | |||.||||.|..     |...||| |. ..  .. | ..... .. .. |. ...|..|||.|||.    .....  ...   . ..|||||
nliegekkkchqYwPdstek----ygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvh

CSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
||||.||||| ...|  |  . ..|  || .... .||.|  |.|||.||.|...| || |
CsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal
Phosphatase Nvec_PTPN13.AA Subfamily.N6.PD 33-287 37 6.6e-71 230.6 In-house 15-291 (295) Show / Hide 
Range on Protein: 33-287
Range on HMM: 15-291/295
Sequence Identity: 37% (105 aa)

EEEFKDLR--EIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGS----SGEDYINANHIR---------VLVD--DDTYHYIATQGPLPNTTKDFW
.|||. |   | . .  ...|. . |..||||.|.||.. ||| |.      .|.||||||.||           |.  . . .||||||.|..| .|||
weefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFW

QMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNTNQPLklGGRFEVSLLKQTNYDSFVQRDIAVKHL-QSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVA
.|.|..   |. |.| . | || || |||||....     |. .|. .. .. .... |.. |.|  .  .. || ...| .|||||||..|  ...|. 
rmvwqensrvivmttkevergknkCarYWPdeetkke--tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfle

YMRS---LATSQAPVVVHCSAGIGRTGALIAVDVALGLMER---DKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACL
 ...     ... |.||||||||||||..| .|. | ..|.   | . ||...|.|.|.||.|..||..||.| |||  
dvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq
Phosphatase Nvec_PTPN13.AA Subfamily.RA.PD 33-289 37 4.4e-67 217.8 In-house 3-264 (266) Show / Hide 
Range on Protein: 33-289
Range on HMM: 3-264/266
Sequence Identity: 37% (97 aa)

EEEFKDLREIKPT-DGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSSG---EDYINANHIRVLVDDDtyHYIATQGPLPNTTKDFWQMIWEQGVEVVAM
||||| | ..|   . .. .. ..| .|||. ..|||. .|| ||  .|    ||||| .|    . |  ..||.|||. .| .|||.|||||. |.|  
eeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekd--kfiaaqGpkeetvedfwrmiweqksativm

VTLDKEGGKVKCHRYWPDNTNqplKLGGRFEVSLLKQTNYDSFVQRDIAVKH----LQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLATSQA
|| .. ||..||||.        |   |.. ..|   ..  ||. |..     .  ||  .. . |  ||. ||| ... |..... ...|   .|  |.
ltelkerkeekcaqywpdeGl---vtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsa

--PVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEV
|||||||.||||..|..|  |  .. ..  |. .... || ||  |.||. || |.||. ||     
nhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlley
Phosphatase Nvec_PTPN13.AA Subfamily.N_Choan_2.PD 55-288 37 8.7e-67 216.7 In-house 20-263 (266) Show / Hide 
Range on Protein: 55-288
Range on HMM: 20-263/266
Sequence Identity: 37% (91 aa)

ANTDKNRYRNVLPYEATRVRLSGSS---GEDYINANHIRVLVDDDTYhYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNTNQP
|.  |||...||  ||||||.  .      |||||..|   ..... |||..||||.|.|.||.||||. |. ..|.|  .| |.|| |||| .... .|
rnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkk-YiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek

LKL-GGRFEVSLLKQTNYDSFVQRDIAVKHlqSGKSIEIAHLNFVKWPDHGVPRSPV------EMVQFVAYMRSLAT--SQ-APVVVHCSAGIGRTGALI
|  |  .|  |.... . .... . ...  .|.. .. |  ...||||||||..       .... .. .|.  ..  |..||||||.|||| |||.| |
vkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtli

AVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
. |.|..|  |... |..||..|  ..|. .|| . ||| .|     
aiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve
Phosphatase Nvec_PTPN13.AA Subfamily.RK.PD 34-290 33 8.7e-66 213.4 In-house 4-266 (267) Show / Hide 
Range on Protein: 34-290
Range on HMM: 4-266/267
Sequence Identity: 33% (90 aa)

EEFKDLREIKPT---DGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSSGE--DYINANHIrvlvD--DDTYHYIATQGPLPNTTKDFWQMIWEQGVEVV
|||. |  . |.   . ||..|.. | .|||. ..|.|. ..|.|    |.  |||||. |    |    . ..|.|||||..|.||||.......   .
eefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaali----dsykrpaafivtqgPlqetvkdfWrlvydencasi

AMVT-LDKEGGKVKCHRYWPDNTNQPLklgGRFEVSLLKQTNYDSFVQRDIAVKHLQSG--KSIEIAHLNFVKWPDH-GVPRSPVEMVQFVAYMRSLATS
 |.| ||.| |.||| .|||..|..     | ..| |.. .    .|.|  .|..|  |  .  |. ...|..||.. .|| |   ...... . .    
vmlteldvevgrvkClkyWPedtevry---gdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee

--QAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
  . ..||||.|| ||.|. ||.|. | ..||..  |. .....||...  |..|..||.|.| . || |
eeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal
Phosphatase Nvec_PTPN13.AA Subfamily.RG.PD 33-289 36 1.9e-65 212.5 In-house 3-262 (264) Show / Hide 
Range on Protein: 33-289
Range on HMM: 3-262/264
Sequence Identity: 36% (94 aa)

EEEFKDLREIKPTD-GCDSGKNQANTDKNRYRNVLPYEATRVRLSGSSG---EDYINANHIRVLVDddTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAM
||.|... ..||.|  ..| |.. |  |||. |....| .||.||. .|   .|||||..|.      . .||.|||||..|..|||.||||..... |.
eeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrr--skeyivtqgplketiedFWrmiWehnaqiivm

VTLDKEGGKVKCHRYWPDNtNQPLKLgGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIE--IAHLNFVKWPDHGVPRSPVEMVQFVAYM-RSLATSQAP
|  .| |. ....|||.. ..||.| ....| ||.... .... ||. .|. .  |. |  . .... ||||.|.| | .... ||..  ... |.|||.
ltdldekgrrdedvyWPkk-deplel-ealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGP

VVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEV
||| ||.| .||.|  |  .|. .  .. |... .| .|.|...|..||.| |.| ||.     
ivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel
Phosphatase Nvec_PTPN13.AA Subfamily.N5_RR.PD 55-288 35 4.8e-65 211.1 In-house 22-262 (265) Show / Hide 
Range on Protein: 55-288
Range on HMM: 22-262/265
Sequence Identity: 35% (85 aa)

ANTDKNRYRNVLPYEATRVRLSG----SSGEDYINANHIRVlVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNTNQ
.. ||||...|| | .|| |.     ..  .|||||.|.   | ..  |.||||||||| .|||.||... |.|. |.|  ||  . ||..|.||...  
gsqtknryktilPnensrvllesessededssyinanyikG-ydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedy

PL-KLGGRFEVSLLKQTNYDSFVQRDIAVKHLQSgKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYM---RSLATSQ-APVVVHCSAGIGRTGALIAVDV
. .  | .|.   . .. . .  | . .|.|..  . .. |  . .|||| .|... .....|. .   |. .. . |||||||||||||||. ||...|
eiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisi

ALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
.  .....  |. ... .|| .| ||.||..|| . ..|  . 
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
Phosphatase Nvec_PTPN13.AA Subfamily.R_Ecdysozoa.PD 33-289 29 1.4e-62 202.9 In-house 3-267 (269) Show / Hide 
Range on Protein: 33-289
Range on HMM: 3-267/269
Sequence Identity: 29% (79 aa)

EEEFKDLR-EIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLS---GSSGEDYINANHIRVLvdDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAM
|||.. |  ...    .  .... |. ||||... ... |||.|.   |.   |||||..|.    ... ..|| |.|. .| .|||.||.|| |... |
eeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgy--kekkkfiaaqdPveatigDfWrmiaeqevtlivm

VTLDKEGGKVkCHRYWPDNtnQPLKLGgRFEVSLLKQTNYDSFVQRDIAVKHLQ---SGKSIEIAHLNFVKWP-DHGVPRSPVEMVQFVAYMRSLAT---
..  .|  .  |..|||..  .  . |    | | .. . . ...|.. | . .     .| ..   ...|. |  ||...  .....  .|.|      
lsnlteknrk-cakyWpie--devqyg-dilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnk

---SQAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEV
  |..|.||||||| ||.| ..|.|. |  .. ..  || .|...||.||. ..|  .||.|.|.| ..  
lsgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady
Phosphatase Nvec_PTPN13.AA Subfamily.N1.PD 49-289 38 1.5e-62 203.0 In-house 21-266 (268) Show / Hide 
Range on Protein: 49-289
Range on HMM: 21-266/268
Sequence Identity: 38% (94 aa)

DSGKNQANTDKNRYRNVLPYEATRVRLSGSSGeDYINANHIRvlVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNT
. | ..| ..||||.| ||. .|..|  ..  |||||. .   ..    .|| ||||||.|.. ||||.|||    | |.    | ...||.||| ....
reaklpenrglnryrdvspydhsrikleradv-dyinaslve--leeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqee

NQ-PLKLGG-RFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMR---SLATSQAPVVVHCSAGIGRTGALIAV
  |.|   ...| |... ... |..| . .. |.. .. || |  . .||| |||.||  ...|.  .|   ||... .|.|.||||||||.|.|  || 
eeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslv

DVALGLMERDKP---FDINQTIRDLREQRQGMIQTKDQYIFCYKACLEV
 | ..|. .     ||.. . .||..| |.||| ||  | | | ||   
dtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg
Phosphatase Nvec_PTPN13.AA Subfamily.N23.PD 49-289 30 1.3e-60 196.9 In-house 102-348 (350) Show / Hide 
Range on Protein: 49-289
Range on HMM: 102-348/350
Sequence Identity: 30% (77 aa)

DSGKNQANTDKNRYRNVLPYEATRvrlSGSSGEDYINANHIRVLVDdDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNT
||..|.. |.   .|... . .      .. .||||| ... |.   . ..||||||...|  |||.|.||| ..|. |.| ..||.| ||..||| ...
gsGqqqgtpdsrhdpnrvklqqst---qpgqqddyinatylkeltp-msPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPide

NQPLKLGGrFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLA-------T---SQAPVVVHCSAGIGRTG
.. . |  ..||| .... . ...|.. ..| .  .  .. ||.. .|...||| || ....|.  ...         |   ..|...|||||.||||..
getnlfgd-lrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtg

ALIAVDVALGLMERDKP-FDINQTIRDLREQRQGMIQTKDQYIFCYKACLEV
  |  |.  .. ...  .| . .| ||.||. |.|.|... ..|.| ||   
tfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea
Phosphatase Nvec_PTPN13.AA Subfamily.RN.PD 47-288 38 6.7e-57 184.3 In-house 18-261 (264) Show / Hide 
Range on Protein: 47-288
Range on HMM: 18-261/264
Sequence Identity: 38% (95 aa)

GCDSGKNQANTDKNRYRNVLPYEATRVRLSGS---SGEDYINANHIrVLVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRY
.. .|.. | .|||...||||. .||.|. .   . .|||||  | .  |  .  ||||||||..|  |||||.||||| |. ..|  .| |.|.|||||
tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasai-ldhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckry

WPDNTNQplkLGGRFEVSLLKQT-NYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYM-RSLATSQAPVVVHCSAGIGRTGALI
. ..   . . .|| |. .    | .. | . .| ||. ..  .. . |. ||..||| |.  ...|   . .|     .|.|||||.| ||||. |..|
wpdeGse---vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyi

AVDVALGLMERD-KPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
. |  . .  |  ||  |.  ||.||.|...||||. |...|  |   
lidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
Phosphatase Nvec_PTPN13.AA Subfamily.R_Nematode_2.PD 52-285 32 2.3e-55 179.2 In-house 25-255 (261) Show / Hide 
Range on Protein: 52-285
Range on HMM: 25-255/261
Sequence Identity: 32% (76 aa)

KNQANTDKNRYRNVLPYEATRVRLSGSSGEDYINANHIRVlvDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNTNQP
. ...||.|| .|   . |.|.         | ||..    . .. ..||||||| ||..||| |.  . || . |..   || ||..|.| .|.| |.|
aaylpkdkhRypdvPCkpetavevivdgkrvpihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqk

LKLGgRFEVSLLKQT--NYDSFVQRDIAVKHLQS-GKSIEIAHLNFVKWPDHGVPRSPVEMVqfvAYMRSLATSQAPVVVHCSAGIGRTGALIAVDVALG
| ||..  ...     |.  .| . |.  .   ..  . |. . .|||.|||.| .|.      ..  |. |.|||||||||||.|.|....    .| |
ldlg-rfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf---eLlelvkksekPivvhCsaGiGRtmafigteylar

LMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKA
.   .......|||.|.  |||. |. .   .     
eveadptieltealkelrehRwkgiqtesqlywltlg
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_1.PD 34-288 29 5.9e-55 178.0 In-house 4-262 (265) Show / Hide 
Range on Protein: 34-288
Range on HMM: 4-262/265
Sequence Identity: 29% (78 aa)

EEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRL-SGSSGEDYINANHIRVLVDDdtYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLD
.||..|.. ....  .. |.. ..|||||..|   . .||.| ....  ||| ||.. . .     ..| .|.|| .|..||||.  . || . |.    
defralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnp--krficaqaPldktiadfwymvlqekveaivmlckl

KEGGKVKCHRYWPDNTNQPLKLGGR-FEVSLLKQTN------YDSFVQRDIaVKHLQSG-KSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRslaTSQA
| ||.||. |.| .... |..  .  .... ....       .....    ..   .| |. .. |... .|||.|||   . ...... .|   .|..|
iekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtv-levegaGektrkvthyqWtdWPdrGvPpadlaalelleavr---gskg

PVVVHCSAGIGRTGALIAVDVALG-LMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
.||||||||||||...|..  |  |.| ..  |... ....||||.  |||||.| ..  |.   
PivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_4.PD 38-288 27 9.3e-53 170.8 In-house 8-261 (264) Show / Hide 
Range on Protein: 38-288
Range on HMM: 8-261/264
Sequence Identity: 27% (71 aa)

DLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGS-SGEDYINANHIRVLvddDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGG
| .. |    .     ..|.|||||...|  ..||| |      .||| |. .|.    | ..||.|||||..| .||| |.... ..|| |.    |.|
dfvkgkappnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP---dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieeg

KVKCHRYWPDNTNQPLKLgGRFEVSLLKQTNY--DSFVQRDIAVKHLQ-----SGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSlATSQAPVVVH
  || ||.|.....  |. |.... |.....      . . . |   .     . . . . |... .|.|.  |  .. ....  ...   ... |.|||
vekcaryypeksekvvkf-GkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk-kkkekPivvh

CSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
||||.||| .|. .| |   .      .. . .|.||. |.. .|.. |..|.   .| 
csaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase Nvec_PTPN13.AA Subfamily.RC.PD 34-288 28 6.5e-50 161.5 In-house 4-285 (288) Show / Hide 
Range on Protein: 34-288
Range on HMM: 4-285/288
Sequence Identity: 28% (82 aa)

EEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRL----------------------SGSSGEDYINANHIRVLVDDDtyHYIATQGPLPNTT
||. | ...       .... | .|||| .||||.  || |                       .  | .|||| .|    . .   |||.|||| .|  
aefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpe--kyiaaqGplketv

KDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWpdntNQPLKLGGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQ
|||.||.|. |.|. |.|  ||| . || .||    ..  .  |  || | .. .  ... | . ... .  .| |. .... .|.....|  | |....
ddfwrmiferkvkvivmltelkeGdrekcaeyw----eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellk

FVA-------Y-MRSLATS---QAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
.           .| | .    .|..|||..| .|||  ||..  |  .| ..  |. | .. || .| .|.....|||.|..  |  
liqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_6.PD 35-290 28 5.2e-48 155.3 In-house 5-252 (253) Show / Hide 
Range on Protein: 35-290
Range on HMM: 5-252/253
Sequence Identity: 28% (73 aa)

EFKDLREIKPTDGCDSgkNQANTDKNRYRNVLPYEATRVRLSGSSgEDYINANHIRVLVDddTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKE
|.||  .. ... . .    ...|.|||.|.  ..|.|..|..   . || || ...  .  .  .| ||.|| .| ..||.||.||| . |.    | |
eykdspneaseseata--flkfkdrnrytniqCcdagrlkladde-dfyihanlvkistk--prrlictqaplegtieefwkmilssgveyivmlcelve

GGKVKCHRYWPDNTNQPLKLGGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSlatSQAPVVVHCSAGI
| |. .| .|.  .  |..   .|  ..... |  ..| . .   ...... . |... .||||||| | .  ..... ...   .. |.|||||||.||
kgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkk---dkkPivvhCsaGv

GRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
||.|. . ..|  .   .  .... .  |||.|   .||. ||.. ..|| |    
GrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl
Phosphatase Nvec_PTPN13.AA Subfamily.R_Nematode_3.PD 51-286 28 2.6e-44 143.1 In-house 18-262 (267) Show / Hide 
Range on Protein: 51-286
Range on HMM: 18-262/267
Sequence Identity: 28% (70 aa)

GKNQANTDKNRYRNVLPYEATRVRLSG---SSGEDYINANHIRVlvdDDTYHYIATQGPL--------PNTTKDFWQMIWEQGVEVVAMVTLDKE---GG
. ... ...|. .|. .|.||| | |      .|.|.|| . .    .  . | ||.|.         .| . ||.|| ...||.|.|.   .|   ...
tslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvec---pnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgee

KVKCHRYWPDNTNQPLKLGGrFEVSL--LKQTNYDSFVQRDIAVkHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSlatSQAPVVVHCSAGI
 || .|.|.. .. ||..| ..|.    |.   .....|.. | ... .| . . || .  |.....| .| |... . ....   |..|||||||.||.
eekcseYypekvdgelkfeg-vsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfvek---sktpvvVHCsdGi

GRTGALIAVDVALGLMERDK-PFDINQTIRDLREQRQGMIQTKDQYIFCYKAC
|...| |....  |. . |  .|. . | .||.||.| |||. ...|      
sRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgi
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_5.PD 33-288 27 8.7e-44 141.2 In-house 3-255 (258) Show / Hide 
Range on Protein: 33-288
Range on HMM: 3-255/258
Sequence Identity: 27% (70 aa)

EEEFKDLREIKPTDGcDSGKNQANTDKNRYRNVLPYEATRVRLSGSSgEDYINANHIRVlvDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLD
..||..| ..||.   .. . ..|..|||. .|  ...|||.|.    ..||||..|..  || ....| || |||.|..|||.|. .. .. | ... |
ktefeklaslkpnke-tckafeknlkknrskdvkilDetrVkltded-dsYinaskikl--ddlekkliltQlPlpdteedFWrmvyqekitsvvllved

KEGGKVKChRYWPDNTNQPLKLGGRFeVSLlKQTNYDSFVQRDIAVKHLQSGKS--IEIAHLNFVKWPDHGVPRSPVEMVQ--FVAYMRSLATSQAPVVV
.|  . ..  ..|..|.. |.||. | .   .... ..  .    |. |  |.|  . . . .. .|... || .  ....     ....   ..|||||
eelketav-sffpletgdylnlgkmf-inn-rkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvv

HCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLE
....|.||.| .....||   ....| ..|..... .|.|| |.... .||. |.| |. 
vsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavld
Phosphatase Nvec_PTPN13.AA PTPc_motif 188-288 40 3.3e-40 140.82 SMART 1-92 (92) Show / Hide 
Range on Protein: 188-288
Range on HMM: 1-92/92
Sequence Identity: 40% (43 aa)

EIAHLNFVKWPDH-----GVPRSPVEMVQFVAYMRSLATSQAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFC
.. |. .  ||||     |||     ...|....|.      |.|||||||.|||| ..|.|... .      .|| ||.. .|.|| ||.||..|||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFC

YKACLE
|...||
YRCILE
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_egg.PD 46-287 26 1.9e-30 97.7 In-house 16-253 (257) Show / Hide 
Range on Protein: 46-287
Range on HMM: 16-253/257
Sequence Identity: 26% (63 aa)

DGCDSGKNQANTDKNRYRNVLPYEATRVRLS---GSSGEDYINANHIRVlvDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGgkVKCHR
.. . .| | . |   | .||.|    |   .|.| ||...   .    ..| .| || || .|||.|.... |.. |.|  ||    .|. |||   ..
islttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkG--kpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--ercey

YWPDNTNQPLKL-GGRFEVSLLKQTNYDSFVQRdiaVKHLQ-SGKSIEIAHLNFVKWpDhgVpRSPVEMVQFVAYMRSLATSQAPVVVHCSAGIGRTGAL
.|..  | ...  ||  .    . |   | .|.  |   |  .|.  .. |  | ...   .  .| |     ||||..  |. ....|.|...||  . 
ywpkaeseslvtvpGslrienlkvdskadplfr---vtklklvGgddeelflehwqg-d--v-nylsdvysplrvlrklrnlskpvvvqdilGvskaatl

IAVDVALGLMERDkP---FDINQTIRDLREQRQGMIQTKDQYIFCYKACL
|  |   . . ...  || .|.  ...  .|.| |.  |           
vaieiallsllrG-pitkslvlravvflrlrrrlsvesvllylfvyrlvl
Phosphatase Nvec_PTPN13.AA Subfamily.N_Fungi_PTP1.PD 57-149 39 1.6e-29 94.6 In-house 46-153 (343) Show / Hide 
Range on Protein: 57-149
Range on HMM: 46-153/343
Sequence Identity: 39% (41 aa)

TDKNRYRNVLPYEATRVRLS-----------GSSGEDYINANHIRVL----VDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCH
||||.|.|||| .||.|              |..||||||....       .  ..|||||.|||.| .||...| . .|.|. ..| | | .  ||.||
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy

RYWPDNTN
|.. .   
rYWqegsy
Phosphatase Nvec_PTPN13.AA Subfamily.N_Fungi_PTP1.PD 178-287 30 5.1e-19 60.0 In-house 204-339 (343) Show / Hide 
Range on Protein: 178-287
Range on HMM: 204-339/343
Sequence Identity: 30% (37 aa)

VKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVA-----------YMRSLATSQAPVVVHCSAGIGRTGALIAVDVALG-------LMERD------
..  |. .|.. .|.| ..   | ...| .               .    ..|..||||||.|||| |...|  || ..        | .| |....  |
pvtaavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldva

-KPFD-INQTIRDLREQRQGMIQTKDQYIFCYKACL
|.||  |.|..||.||.|.| |              
aktrDlisiivnelrkqrismvqnldqfifiYeall
Phosphatase Nvec_PTPN13.AA Family.DSP.PD 120-284 16 1.7e-14 45.5 In-house 130-241 (387) Show / Hide 
Range on Protein: 120-284
Range on HMM: 130-241/387
Sequence Identity: 16% (28 aa)

EQGVEVVAMVTldkeggkvkchrywpdntnqplklggrfevsllkqT------NydsfvqrdiavkhlqsgkSIEIAHLNFvKWPDHGVPRSPVEMVQFV
| || ..  .|                                   .      .                  . .|..|..  ..||..|     .....
elgvtkivnlt-----------------------------------ddkpqftk------------------elgikylri-pidDhnapplenlfekai

AYMRSLATSQAPVVVHCSAGIGRTGALIAVdvalGLMERdKPFDINQTIRDLREQRQGMIQTKDQYIFCYK
 .. .   |.  |.||| ||.||.| ||.      ||.. . .  ..... .|..|.|.|. .....  .|
dfieegndskgvVlVHCkaGkgRsgtliia----Ylmks-egltleealdwvrskRpgvitpnqgflkqlk
Phosphatase Nvec_PTPN13.AA Subfamily.PTPDC1.PD 188-281 30 9.2e-14 43.0 In-house 134-219 (229) Show / Hide 
Range on Protein: 188-281
Range on HMM: 134-219/229
Sequence Identity: 30% (29 aa)

EIAHLNFvKWPDHGVPrSPVEMVQFVAYMRSlATSQAPVVVHCSAGIGRTGALIAVdvalgLMERDKPFDINQTIRDLREQRQGMIQTKDQYIF
.|.. ||  ..|.||. |  .... |  . . | ... . ||| || |||| |||       .   | .. .. |. .|..|   |||..|  .
giyfynf-glkDygva-sleriLdivkvvdf-aleegkiavHCHAGlGRtGvliac-----ylvyakrltaeeaiklvrskrpksiqtreqvel
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_eak.PD 43-215 21 1.5e-13 42.3 In-house 13-178 (281) Show / Hide 
Range on Protein: 43-215
Range on HMM: 13-178/281
Sequence Identity: 21% (37 aa)

KPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSS--GEDYINANHIRvlVDDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKC
..      ..   . ..||  ...|..   |||. |    . ||||  .     .   .|| |  .  .    ||||. ||. ..  | | .  |  .|.
qrllsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslae--fsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleks

HRYWPDNTnQPLKLGgRFEVSLLKQ-TNYDSFVQRDIAVKHlqSGKSIEIAHLNFVKWPDHGVPRspveMVQFVAY
||.| . || |  ..|   .   . . .  | . ..     .. .. | ..  | .  .|.    . .|.|.    
dkyfpdkt-evlkyG-ildverkeyavkrniletrllilrk--GnethrvlhykvfGwtettlpk----yedflal
Phosphatase Nvec_PTPN13.AA Subfamily.DSP23.PD 191-278 27 2.2e-11 35.6 In-house 35-116 (128) Show / Hide 
Range on Protein: 191-278
Range on HMM: 35-116/128
Sequence Identity: 27% (24 aa)

HLNFVKWPDHgVPRSPVEMVQFVAYMRSLATSQAPVVVHCSAGIGRTGALIAVDvalgLMeRDKPFDINQTIRDLREQRQGMIQTKDQ
|. .. ||.  | ..  ....|  .     .. .| |||  |.||||.|.|      |. . . .  ...| ..|..|.| |.|..| 
tlrridipdf-cPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacy----lv-keeglaaddaiaevrkrrkGsietveq
Phosphatase Nvec_PTPN13.AA Subfamily.CDC14.PD 215-279 31 1.1e-08 26.6 In-house 190-249 (258) Show / Hide 
Range on Protein: 215-279
Range on HMM: 190-249/258
Sequence Identity: 31% (20 aa)

YMRSLATSQAPVVVHCSAGIGRTGALIAVdvalGLMErDKPFDINQTIRDLREQRQGMIQTKDQY
... . ...  ..||| ||.||||.||.      |.     |  ..||  ||  | |.. .. | 
fleitekaeGaiavhCkaGLGrtgtligc----ylik-hyrftaaetiawlriarPGsvigpqqt
Phosphatase Nvec_PTPN13.AA Subfamily.PRL.PD 187-284 30 2.6e-08 25.4 In-house 47-137 (140) Show / Hide 
Range on Protein: 187-284
Range on HMM: 47-137/140
Sequence Identity: 30% (30 aa)

IEIAHLNFvkwPDHGVPRSPVEMVQF-VAYMRSLATSQAPVVVHCSAGIGRTGALiavdVALGLMERDkpFDINQTIRDLREQRQGMIQTKD-QYIFCYK
||.  |.|    | .|| . |    . .  ..   .... | ||| ||.||.  |    ||| |.|    .. ....  .||.|.| | .|...  ||  
ievldlaf---ddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvl----valalieaG--mkyedavefirekrrgainskqlkflekyk
Phosphatase Nvec_PTPN13.AA Subfamily.DSP19.PD 207-270 25 2.6e-06 18.9 In-house 66-121 (139) Show / Hide 
Range on Protein: 207-270
Range on HMM: 66-121/139
Sequence Identity: 25% (16 aa)

VEMVQFVAYMRSlatSQAPVVVHCSAGIGRTGAliavdVALGLMERDKPFDINQTIRDLREQRQ
|...|.   ||   ..  |.|||.||. |. .     |... . .|.  ....... .||.|. 
kealdFieears---kdgrvlvHCnAGvSRsas-----vviaylmkdeelslekalekvrearp
Phosphatase Nvec_PTPN13.AA Subfamily.N_Nematode_eak.PD 221-290 21 4e-06 17.9 In-house 210-280 (281) Show / Hide 
Range on Protein: 221-290
Range on HMM: 210-280/281
Sequence Identity: 21% (15 aa)

TSQAPVvVHCSAGIGRTGALIAVDVALGLMERD--KPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL
| ||. . .. |  |.|... .|. . |..      . ... |   ...|.  . .. |. | |.. |. | 
psfapi-iqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
Phosphatase Nvec_PTPN13.AA Subfamily.PTEN.PD 211-242 38 7.2e-06 17.1 In-house 80-113 (305) Show / Hide 
Range on Protein: 211-242
Range on HMM: 80-113/305
Sequence Identity: 38% (13 aa)

QFVAYMRS-LATS-QAPVVVHCSAGIGRTGALIA
..|  . . |  . .  |.||| || |||| .|.
eivedvdkwLkedksnVvavHCkaGkGRtGvmic
Sequence
Name Sequence Type Origin Length Description Download
Nvec_PTPN13.AA Protein None 296 None Fasta, JSON
Nvec_PTPN13.NA RNA None 888 None Fasta, JSON
Nvec_PTPN13.AA.PD_31-291 Protein Phosphatase Domain None 261 None Fasta, JSON