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Gene Nvec_PTPRD2

Nvec_PTPRD2
Species: N.vectensis
Alias: Nvec_PTPRD2, Nvec_224730
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: R_Anemone_2
Protein domain

Protein domains of Nvec_PTPRD2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Nvec_PTPRD2.AA Y_phosphatase 1-56 38 2.3e-14 51.62 Pfam 75-136 (243) Show / Hide 
Range on Protein: 1-56
Range on HMM: 75-136/243
Sequence Identity: 38% (24 aa)

QVTNCEERGR-IK-CHQYWPS---SGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGS--PEE
...||.|.|| .| ||||||.   .....|| ..|...|. ...|||.| | |.  |.   |.
MLCNCMEMGRDEKTCHQYWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQET
Phosphatase Nvec_PTPRD2.AA Subfamily.R_Anemone_2.PD 2-59 51 3.7e-25 79.6 In-house 101-158 (262) Show / Hide 
Range on Protein: 2-59
Range on HMM: 101-158/262
Sequence Identity: 51% (30 aa)

VTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEESCI
.|..||||..|.|.||||.||..||...|.....||||||..|||.|||....||  .
ltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqv
Phosphatase Nvec_PTPRD2.AA Subfamily.RA.PD 2-52 41 4.7e-16 49.6 In-house 101-151 (266) Show / Hide 
Range on Protein: 2-52
Range on HMM: 101-151/266
Sequence Identity: 41% (21 aa)

VTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG
.|. .||.. ||.||||. |.  || |.|..  ...| |||.| | |.. .
ltelkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlp
Phosphatase Nvec_PTPRD2.AA Subfamily.RB.PD 2-51 34 8.3e-15 45.5 In-house 100-150 (261) Show / Hide 
Range on Protein: 2-51
Range on HMM: 100-150/261
Sequence Identity: 34% (17 aa)

VTNCEERGRIKCHQYWPSSG-SQNYGVIHVNMMSTVELSDYTIRSFGVKRS
.|.. |.|..||..|||..  ...|| |.|..... ||....||.| ... 
ltqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekg
Phosphatase Nvec_PTPRD2.AA Subfamily.R_Sponge_2.PD 2-55 35 2.3e-14 44.1 In-house 98-153 (262) Show / Hide 
Range on Protein: 2-55
Range on HMM: 98-153/262
Sequence Identity: 35% (20 aa)

VTNCEERGRIKCHQYWPSS--GSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPE
.|| ||.|. ||..|||.   ....|| ..|.. .. .|.||.|| . .... | |
ltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskeksse
Phosphatase Nvec_PTPRD2.AA Subfamily.R_Anemone_1.PD 3-59 33 5.2e-14 43.2 In-house 100-155 (258) Show / Hide 
Range on Protein: 3-59
Range on HMM: 100-155/258
Sequence Identity: 33% (19 aa)

TNCEERGRIKCHQYWPSsGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEESCI
|| .|    |||||||. ....|| ..|..... . .||.||.. ...... ||  .
tnliegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerev
Phosphatase Nvec_PTPRD2.AA Subfamily.RK.PD 2-55 31 1e-13 41.7 In-house 102-156 (267) Show / Hide 
Range on Protein: 2-55
Range on HMM: 102-156/267
Sequence Identity: 31% (17 aa)

VTNC-EERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPE
.|.   |.||.|| .|||  ....|| |.|.....  ..|. .| | |..   . 
lteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargq
Phosphatase Nvec_PTPRD2.AA Subfamily.N6.PD 2-51 40 4e-13 39.9 In-house 128-178 (295) Show / Hide 
Range on Protein: 2-51
Range on HMM: 128-178/295
Sequence Identity: 40% (20 aa)

VTNCEERGRIKCHQYWPSSGS-QNYGVIHVNMMSTVELSDYTIRSFGVKRS
.|.  |||. || .|||.... ...|||.|...|  . .|||.| | |.. 
ttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshk
Phosphatase Nvec_PTPRD2.AA Subfamily.N9.PD 2-52 34 9.8e-13 38.8 In-house 100-152 (275) Show / Hide 
Range on Protein: 2-52
Range on HMM: 100-152/275
Sequence Identity: 34% (18 aa)

VTNCEERGRIKCHQYWP--SSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG
.| ..||||.|| ||||  .  |...| ..|. ..... .||..|.. .|.. 
ttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvk
Phosphatase Nvec_PTPRD2.AA Subfamily.N3.PD 2-57 35 2e-12 37.5 In-house 100-156 (261) Show / Hide 
Range on Protein: 2-57
Range on HMM: 100-156/261
Sequence Identity: 35% (20 aa)

VTNCEERGRIKCHQYWPSSG-SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEES
.|.  ||||.|||||||... ....| ..|.. .. | . | .| . .|.. . || 
lttlverGrvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeer
Phosphatase Nvec_PTPRD2.AA Subfamily.N_Choan_1.PD 2-55 32 2.2e-11 34.3 In-house 100-154 (262) Show / Hide 
Range on Protein: 2-55
Range on HMM: 100-154/262
Sequence Identity: 32% (18 aa)

VTNCEERGRIKCHQYWPSSG-SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPE
||.  | |..|||.|||    . ..| . |...|. | . |  | | ..|... .
vtreieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresget
Phosphatase Nvec_PTPRD2.AA Subfamily.RC.PD 2-51 32 5.2e-11 32.9 In-house 119-167 (288) Show / Hide 
Range on Protein: 2-51
Range on HMM: 119-167/288
Sequence Identity: 32% (16 aa)

VTNCEERGRIKCHQYWpSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRS
.|...|  | || .||   | . || . |..  |   |||..| . ....
ltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnk
Phosphatase Nvec_PTPRD2.AA Subfamily.RG.PD 2-51 32 6.5e-11 32.8 In-house 101-151 (264) Show / Hide 
Range on Protein: 2-51
Range on HMM: 101-151/264
Sequence Identity: 32% (16 aa)

VTNCEERGRIKCHQYWPS-SGSQNYGVIHVNMMSTVELSDYTIRSFGVKRS
.|. .|.|| ....|||.  .. ... ..|...|. .||.||.|.| .|  
ltdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlknt
Phosphatase Nvec_PTPRD2.AA Subfamily.RN.PD 2-50 38 2.6e-10 30.6 In-house 102-151 (264) Show / Hide 
Range on Protein: 2-50
Range on HMM: 102-151/264
Sequence Identity: 38% (19 aa)

VTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMST-VELSDYTIRSFGVKR
.|. || |  .|..|||  ||. |..  |...|  .   || .||| .| 
ltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylkn
Phosphatase Nvec_PTPRD2.AA Subfamily.N5_RR.PD 2-55 27 6e-10 29.5 In-house 99-156 (265) Show / Hide 
Range on Protein: 2-55
Range on HMM: 99-156/265
Sequence Identity: 27% (16 aa)

VTNCEERGRIKCHQYWPSSGS----QNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPE
.|. .|. | ||..|.| . .    ..|| ..... ..||  ||..|.. .| . . |
ltklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerve
Phosphatase Nvec_PTPRD2.AA Subfamily.R_Ecdysozoa.PD 2-51 36 1.1e-09 28.5 In-house 101-149 (269) Show / Hide 
Range on Protein: 2-51
Range on HMM: 101-149/269
Sequence Identity: 36% (18 aa)

VTNCEERGRIkCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRS
..| .|  |  |..|||    ..|| | |...|. . |||.||.. | . 
lsnlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskk
Phosphatase Nvec_PTPRD2.AA Subfamily.N13.PD 2-55 33 4.8e-09 26.7 In-house 97-153 (259) Show / Hide 
Range on Protein: 2-55
Range on HMM: 97-153/259
Sequence Identity: 33% (19 aa)

VTNCEERGRIKCHQYWPSSGSQNYGV---IHVNMMSTVELSDYTIRSFGVKRSGSPE
||.  |.|..|||.|||.. ...  |   ..|... ...|.....|.. || | | |
vtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesge
Phosphatase Nvec_PTPRD2.AA Subfamily.N12.PD 6-52 28 3.3e-08 23.6 In-house 110-159 (270) Show / Hide 
Range on Protein: 6-52
Range on HMM: 110-159/270
Sequence Identity: 28% (14 aa)

EERGRIKCHQYWPSSGSQN--YGVIHVNMMSTVELS-DYTIRSFGVKRSG
| |..||..|||..| ..  .| ..|....   .. |..||.. |.... 
velgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaqk
Phosphatase Nvec_PTPRD2.AA Subfamily.N_Choan_2.PD 2-53 28 5.3e-08 23.0 In-house 96-151 (266) Show / Hide 
Range on Protein: 2-53
Range on HMM: 96-151/266
Sequence Identity: 28% (16 aa)

VTNCEERGRIKCHQYWPSSGSQNY----GVIHVNMMSTVELSDYTIRSFGVKRSGS
.|. ||.|| || .|||..  ..     | |.|  .|..  . | ..   ....|.
ttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkge
Phosphatase Nvec_PTPRD2.AA Subfamily.N_Fungi_PTP1.PD 2-53 22 6.5e-07 19.2 In-house 133-185 (343) Show / Hide 
Range on Protein: 2-53
Range on HMM: 133-185/343
Sequence Identity: 22% (12 aa)

VTNCEERGRIKCHQYWPSSGSQNYGVIHVNM-MSTVELSDYTIRSFGVKRSGS
.|.  | .. ||..||.  . ... |   ..  ....  | ...|..||.  |
ltsdvelnlekcyrYWqegsydditvklaskwenimgindsslysadvkkeas
Phosphatase Nvec_PTPRD2.AA Subfamily.N23.PD 2-45 26 7.1e-07 19.2 In-house 178-223 (350) Show / Hide 
Range on Protein: 2-45
Range on HMM: 178-223/350
Sequence Identity: 26% (12 aa)

VTNCEERGRIKCHQYWPSSG--SQNYGVIHVNMMSTVELSDYTIRS
.|. .|... ||.||||     ....| ..| . |. . . .  | 
ltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwierv
Phosphatase Nvec_PTPRD2.AA Subfamily.N14.PD 1-28 33 1.1e-06 18.7 In-house 100-127 (275) Show / Hide 
Range on Protein: 1-28
Range on HMM: 100-127/275
Sequence Identity: 33% (9 aa)

QVTNCEERGRIKCHQYWPSSGSQNYGVI
..|. || |. |...|.|...|..  | 
mlteeeedgkeksfkylPkleskkktve
Phosphatase Nvec_PTPRD2.AA Subfamily.N_Nematode_1.PD 3-36 24 4.7e-06 16.7 In-house 99-132 (265) Show / Hide 
Range on Protein: 3-36
Range on HMM: 99-132/265
Sequence Identity: 24% (8 aa)

TNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTV
.. |.|..||..|.|..  ..  . . .   || 
ckliekgkkkcaeyfpakegeklefkekgqkitv
Sequence
Name Sequence Type Origin Length Description Download
Nvec_PTPRD2.AA Protein None 60 None Fasta, JSON
Nvec_PTPRD2.NA RNA None 180 None Fasta, JSON
Nvec_PTPRD2.AA.PD_1-56 Protein Phosphatase Domain None 56 None Fasta, JSON