• Phosphatome.Net

Gene Nvec_PTPRN

Nvec_PTPRN
Species: N.vectensis
Alias: Nvec_82385, Nvec_PTPRN
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RN
Protein domain

Protein domains of Nvec_PTPRN.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Nvec_PTPRN.AA Subfamily.RN.PD 183-446 77 7e-159 518.3 In-house 1-264 (264) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-264/264
Sequence Identity: 77% (205 aa)

RLNKEWEALCNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIV
||.|||||||.||||||.....|..|||.|||...||||||.||.|.|.|.|. |||||||.|.|||||.||||||||||..|..|||||||||||||||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvviv

NLTRLSDLGLPQCHRYWPEDGHETYHIYEVHLVSEHIWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPIVV
|||||.. |. ||.||||..|.|.|||||||||||||||||||||||||||||||||||||||||||||. .||...|.||||||||||..|||||||||
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivv

HCSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEEVN
||| |.||||.||||||||.....|.||||||||.||||||||..||||.||||||||||||||
hcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevn
Phosphatase Nvec_PTPRN.AA PTPc 183-446 33 1.6e-114 387.71 SMART 1-308 (308) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-308/308
Sequence Identity: 33% (105 aa)

RLNKEWEALCNYEAEPS--------VADLGKQDKNV--RKNRYS-DVLPYDHNRVSLRETANA----TGSDYINASFITDHDPRNPAYIATQGPLAHTVS
 ...|.| |.... ...          . .. ..|.  .||||. |...|||.|| |  .        |||||||..|  . .|. .||.||||| ||..
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE

DFWQMVWEQGVVVIVNLTRLSDL--------GLPQCHRYWPEDGHETYHIYEVHLVSEHIWCDDYLVRSFYLKNLQT--------SETRTVTQFHFLSWP
|||.|||.|.. .|| |... .         |   ||.|||..  .||. ..|...||....||| .| |...| ..        |||||||..|. .||
DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DLNVPTTPKPLLEFRRKVNKCFRGR-------------------SCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKA
|..|| .|...|.|.|.|... . .                   . ||||||| |.||||....|| ..... .    .||  .| ..|.|||.|| |..
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----VDIFQIVKMMRNQRPGMVQTEE

QFEFALTAVAEEVN
|. |   ...| . 
QYIFCYRCILEYIK
Phosphatase Nvec_PTPRN.AA Y_phosphatase 209-443 42 5.2e-110 376.58 Pfam 1-243 (243) Show / Hide 
Range on Protein: 209-443
Range on HMM: 1-243/243
Sequence Identity: 42% (105 aa)

NVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGL-PQ-CHRYWPE---DG
| .||||.|...|||.|| |  . .  .||||||..|. ..... |||.||||. ||. |||.|||.|.. .|| |... . |   . ||.|||.   ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

HETYHIYEVHLVSEHIWCDDYLVRSFYLKNLQT--SETRTVTQFHFLSWPDLNVPTT-PKPLLEFRRKVNKCFR-GRSC--PIVVHCSGGVGRTGCYILI
 .||  ..|..|||.  |.|| || | ..| ..  .||||||..|...||| .|| . ||..|.|.|.|.|. . ....  ||||||| |.||||....|
PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI

DLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
| .. .| .. .  ||  .|.|.| |||.|| | .|..|   ...|
DIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Nvec_PTPRN.AA Subfamily.R_Anemone_2.PD 184-445 43 1.5e-83 271.6 In-house 2-261 (262) Show / Hide 
Range on Protein: 184-445
Range on HMM: 2-261/262
Sequence Identity: 43% (112 aa)

LNKEWEALCNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFItDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVN
|..|.|.| . |.... ..   .. | .||||...|.||. || |..... .|||||||..| |   |. ||||||.||..|..|||.|||||.  ||| 
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyi-dGyrrkkayiatqaPlpetiedfWrmvWeqnsavivm

LTRLSDLGLPQCHRYWPEDGHETYHIYEVHLVSeHIWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCF-RGRSCPIVV
||.... |  ..|||||..| ..|    |.| . .. ..||..||| .|. ...|.|.| |||. ||||.||. .  ||.. |.|.|   .    |||||
ltqeeergkakvhryWPskgsrsygklvvelke-evelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivv

HCSGGVGRTGCYILIDLVLNKMMRgAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEEV
||.|||||| .| .| .|...    . .|.  ||..||.||. ||.|| |.||... | .   
hcsaGvGrtGvfiavdillerika-ealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase Nvec_PTPRN.AA Subfamily.R_Anemone_1.PD 186-444 41 7.7e-80 259.5 In-house 4-256 (258) Show / Hide 
Range on Protein: 186-444
Range on HMM: 4-256/258
Sequence Identity: 41% (106 aa)

KEWEALCnyEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRnPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLT
.|.. |   |..    . .....| .||||.|....|| || |... |   |||||||..  .| .  |.||||.|| .||.|||.|||.. . ||| ||
aefqrlk--eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekigviVmLt

RLSDLGLPQCHRYWPEdGHETYHIYEVHLVSEHIWCdDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPIVVHCS
 | .    .||.|||. ..|.|  ..|.| ..     || .|.. |.. ...|.|.|.|.||..|||  ||.. . .|..||||.|  .  . |.|||||
nliegekkkchqYwPd-stekygelrvslrkkevfa-dyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCs

GGVGRTGCYILIDLVLNKMmRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEE
 |||||| .. || .|... .  | .||  .|. .| .|||||.|| |. |  .|| | 
aGvgRtGaflvidamleqa-kkekvvDifnyvkairedrphmvqtkeqyvfihlavlea
Phosphatase Nvec_PTPRN.AA Subfamily.N12.PD 201-445 43 7.6e-78 252.6 In-house 24-269 (270) Show / Hide 
Range on Protein: 201-445
Range on HMM: 24-269/270
Sequence Identity: 43% (108 aa)

ADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDpRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWP
.. |....||.|||| |.||||..|| |... .  |||||||.||   .  . .|||.||||..|..|||.|.||. | ..| . |. .||.|.||||| 
teagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgve-gkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp

EDGHET--YHIYEVHLVSEHIWCDDYLVRSFYLKNLqtSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPIVVHCSGGVGRTGCYILID
|.|.  .  .|| | .|.   ||.|.|.. ...   .|.|.|.|||. .||| .||...|.|||. ..|..  .  . |.||||| ||||||  | ||.|
eegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaid

LVLNKMMRGAK--EIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEEV
 . . ..    |.|.   | .|| ||. .|.|| |.|.   |||| |  
yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
Phosphatase Nvec_PTPRN.AA Subfamily.RA.PD 184-443 39 1.3e-77 252.0 In-house 2-263 (266) Show / Hide 
Range on Protein: 184-443
Range on HMM: 2-263/266
Sequence Identity: 39% (102 aa)

LNKEWEALCNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNpAYIATQGPLAHTVSDFWQMVWEQGVVVIVN
|..|...| . .   .  .......| .|||. ..||||..|| |        |||||||||  .  ..  .||.|||...|| |||.|.||||| || |
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekd-kfiaaqGpkeetvedfwrmiweqksativm

LTRLSDLGLPQCHRYWPEDGHETYHIYEVHLvSEHIWCDDYLVRSFYLK----NLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSC-
 . .  .|..|||..|  ||    |..  ..  . || || | ..    . .  ..| |.|||| |||.. ||...| .|.. .||.|. .  .  ||||
ltelkerkeekcaqywpdeGlvtyGeirvev-kdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh

PIVVHCSGGVGRTGCYILIDLVLNkMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
||| |||||| .| .| ||. ...  . .|.  .|..|| |||.||.|. |.||   .. |    
pivvhcsaGvGrtGtfivldavle-rvkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle
Phosphatase Nvec_PTPRN.AA Subfamily.N_Choan_1.PD 199-444 41 2.1e-76 248.0 In-house 16-260 (262) Show / Hide 
Range on Protein: 199-444
Range on HMM: 16-260/262
Sequence Identity: 41% (103 aa)

SVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPrNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRY
..|   |.|.|| |||||..  ||. || . .. ... .|||||.|.   .  . .|||||||. ... .|||||||| |..|| .||  . |  .||||
ntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykg-ekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChry

WPEDGHET-YHIYEVHLVSEHiWCDDYLVRSFYLkNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRS-CPIVVHCSGGVGRTGCYIL
||.. .|. .  . |. .||.     |. | | | . ...|||.|.|.....|||  ||.|.| |||||..|.|. . .. .|.|.||| ||||||.|| 
WPdenselklgdvtvkslsee-ekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyia

IDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEE
.| ..... . |...|. |.|..|| .|  ||.| .|.||   || . 
lDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
Phosphatase Nvec_PTPRN.AA Subfamily.RB.PD 203-442 39 4.2e-75 243.7 In-house 20-257 (261) Show / Hide 
Range on Protein: 203-442
Range on HMM: 20-257/261
Sequence Identity: 39% (96 aa)

LGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNpAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPED
.. .|  |||.. .|||||.|| | .... ...|||||..| ..  ..  |||||||| .|| |||.||||. . .|| ||.| . |  .|..|||.|  
aaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspr-eyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPad

G-HETYHIYEVHLVSEHIwCDDYLVRSFYLKNlqTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGR--SCPIVVHCSGGVGRTGCYILIDL
  .|   .|.|..|.   |.. .|.| ...   .|.|.|.|.||.|||| .|| ..|.||.| |.|..  . .  . ||||||| |||||| .| .| .|
eepvlyGdikvtllaeke-ldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdr

VLNKMMRgAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVA
... .    .|....| .|| .| ..|.|..|. |  ....  
llqaiee-ndyvdvfgvvaelReeRnllvqtekqyifihecll
Phosphatase Nvec_PTPRN.AA Subfamily.R_Sponge_2.PD 201-445 41 5.3e-74 240.3 In-house 17-261 (262) Show / Hide 
Range on Protein: 201-445
Range on HMM: 17-261/262
Sequence Identity: 41% (103 aa)

ADLGKQDKNVRKNRYSDVLPYDHNRVSLREtANATGSDYINASFITDHDPRNpAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWP
. .|...|| |||....||||..|| ||.  . ..||||||||.  .  |. ||||||||| .||.||| ||||. |  || ||| . |  .|..|||| 
lsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrk-ayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWP

ED--GHETYHIYEVHLVSEHIwCDDYLVRSFYLKNLQTSET-RTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFR-GRSCPIVVHCSGGVGRTGCYIL
  .. .|  ..| |..|.    || .| . |.. ..||  ..||||||..||. .||..  .|||. ..|..  .  .. .|.|.|| |||||| .| .|
ekvdeeveygkfkvtlkeeek-ladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfia

IDLVLNKMmRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEEV
 ||... .  .|||.  ....|| .|. .|...||..|   |..| .  
ldsvlerl-kaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi
Phosphatase Nvec_PTPRN.AA Subfamily.N3.PD 202-442 40 3.2e-73 237.4 In-house 19-257 (261) Show / Hide 
Range on Protein: 202-442
Range on HMM: 19-257/261
Sequence Identity: 40% (99 aa)

DLGKQDKNVRKNRYSDVLPYDHNRVSLRETANatgsDYINASFITDHDPR---NPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRY
.  .. .|. |||| |.||||. ||.|.|. .    |||||...    |       |||||||||.|..||||||||| . .|| || | . |.||.|||
saarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqy

WPEDGHE-TYHIYEVHLVSEhIWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPIVVHCSGGVGRTGCYILI
| ..| ..  ..|.. .|      |..| ..||. .|.| |...|. .|.||| .||. .. .||| ..|.|. .|.. |.|||||.|.|||| .||...
WPetedelefgefsvrceke-detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlill

DLVLNkMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVA
 |  ..  |... . . | ..||||  .|.|..|..|   |.   
etala-lieaaepvypldivrtmrdqramlvqtvsqykfvCeail
Phosphatase Nvec_PTPRN.AA Subfamily.N6.PD 183-443 37 1.8e-70 228.8 In-house 13-292 (295) Show / Hide 
Range on Protein: 183-443
Range on HMM: 13-292/295
Sequence Identity: 37% (105 aa)

RLNKEWEALCNYEAEPSV-ADLGKQDKNVRKNRYSDVLPYDHNRVSLRET-ANATGSDYINASFI--------TDHDPR----NPAYIATQGPLAHTVSD
...|.| |...|.|     . |.. .| .|||| ..||.||.|| |...  . .|||||||..|        . . .        ||||||.|.||||||
gfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsd

FWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDGHE-TYHIYEVHLVSEhIWCDDYLVRSFYLKNL-QTSETRTVTQFHFLSWPDLNVPTTPKPLLEFR
.|||..   ||| .|.  . |  .| ||||. ... ..  ..|. .||    .|| .| | ...  . .|.|.. |.|| .||| .||. |. .|.| ..
FWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisE-kstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfl

RKVNKCFR--GRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGA--KEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
|||  .   .. ||||||| |.|||| .|.|| ||. . .     .|||  .....| ||  .|.|.||..| ..||.   
edvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf
Phosphatase Nvec_PTPRN.AA Subfamily.RG.PD 184-442 33 1.6e-69 225.5 In-house 2-260 (264) Show / Hide 
Range on Protein: 184-442
Range on HMM: 2-260/264
Sequence Identity: 33% (87 aa)

LNKEWEALCNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDpRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVN
|....|.. . ...   |.  |. .| .|||......... ||.|.....  |.||||||.|. .  |. .||.|||||..|. |||.|.||.. .|| |
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyr-rskeyivtqgplketiedFWrmiWehnaqiivm

LTRLSDLGLPQCHRYWPE-DGHETYHIYEVHLVSEHIWcDDYLVRSFYLKNLQTSETRT--VTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPI
| | . |  ....|||. |. ...  ..| |.|..   ..| ||.| ||| .. . ..  |.|.|. .||| ..|.   . | | .|... . .. ||||
ltdldekgrrdedvyWPkkdeplelealkvtllskekl-skytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPi

VVHCSGGVGRTGCYILIDLVLNKmMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVA
|.| ||||.| || .| .|.. ..  . ...  .. ..| .||..|.|. |. |   |.   
vvhdsaGvgragtyialdtllqq-lekeeavnvyqvlklirakRpglvtteEqyvfiydall
Phosphatase Nvec_PTPRN.AA Subfamily.RK.PD 184-444 37 1.6e-69 225.3 In-house 2-265 (267) Show / Hide 
Range on Protein: 184-444
Range on HMM: 2-265/267
Sequence Identity: 37% (101 aa)

LNKEWEAL--CNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANAtGSDYINASFItDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVI
| .|.|.|    .| .    | .|.|.| .|||. |.|.||. .| |  . .   ||||||..| |   |  |.|.||||| .|| |||..|....   |
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaali-dsykrpaafivtqgPlqetvkdfWrlvydencasi

VNLTRL-SDLGLPQCHRYWPEDGHETYHIYEVHLVSEHIWCdDYLVRSFYLKN--LQTSETRTVTQFHFLSWPDL-NVPTTPKPLLEFRRKVNKCFRG-R
| || |  . |  .| .|||||.. .|   .|.||. .. . |..|| | ...   . .|.|.| ||.||.||.  .||.  . ||..|.|.|     . 
vmlteldvevgrvkClkyWPedtevrygdikvelveaelda-dlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeee

SCPIVVHCSGGVGRTGCYILIDLVLNkMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEE
 .|||||. | ||.|..| || ||. |..  . .|.  .|  ||.... ||.|. |..|   .. |  
eGrivvhClaGaGrsGtfiaidivle-mieregvvdvfnavktlrnrkvnmveteeqykfvydvilea
Phosphatase Nvec_PTPRN.AA Subfamily.N9.PD 186-443 42 6.2e-69 223.7 In-house 4-272 (275) Show / Hide 
Range on Protein: 186-443
Range on HMM: 4-272/275
Sequence Identity: 42% (111 aa)

KEWEALCNYEAEpSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDpRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLT
||.... | ..|   ..  |.  |..||||.||| ||. || | .. . . ||||||.|.  .  .. |.||||||| .||||||.||||| |.|||  |
keyadirnepve-GtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGyk-qkkafiatqGplkktvsdfwrmvweqevlvivmtt

RLSDLGLPQCHRYWP--EDGHETYHIYEVHLVSEHIwCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNK------------
|. . |  .| .|||  |.  . .  ..|. |. .   .|| ||.. .|| .|.|.|.|| | ||||||  || . . ||....|| ... .  ||||||
rvvergrlkcgqywpleeessaefgdlsvsnvevev-eedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

-CFRGRSCPIVVHCSGGVGRTGCYILIDLVLNKMmRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
| |.|||| .| .|. |... .    .|.  ||..|| || ....|. |.||   || |              
skghlsgPPivvhcsaGiGrtGtfitldiclarl-eevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase Nvec_PTPRN.AA Subfamily.R_Ecdysozoa.PD 184-443 33 2e-68 221.7 In-house 2-266 (269) Show / Hide 
Range on Protein: 184-443
Range on HMM: 2-266/269
Sequence Identity: 33% (90 aa)

LNKEWEALCNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNpAYIATQGPLAHTVSDFWQMVWEQGVVVIVN
|..|.| | .    .  .  .... |  |||| |. ..|..|| |...     |||||||||  .. ..  .|| |.|.  |. |||.|..|| | .|| 
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekk-kfiaaqdPveatigDfWrmiaeqevtlivm

LTRLSDLGLPqCHRYWPEDGHETYHIYEVHLVSEHIwCDDYLVRSFYLKNLQ---TSETRTVTQFHFLSWP-DLNVPTTPKPLLEFRRKVNKCFRG----
|. |..     |..|||..    |    |.||||.  ..||  |.... . .     ..| |.|... .|. | .|| ... ||.. ..|..  .     
lsnlteknrk-cakyWpiedevqygdilvklvseek-hsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkls

-RSCPIVVHCSGGVGRTGCYILIDLVLNKMmRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
    ||||||| ||||.| .. .||.|... .  ...|| .|| .|| ||. .|..|..|   |.|.  
gsrsPivvhCsaGvgrsgifvaldlllqql-kaedkvdifetvkkLrsqrnllvqsleqyvflyralad
Phosphatase Nvec_PTPRN.AA Subfamily.N13.PD 186-442 38 8.5e-68 219.9 In-house 4-255 (259) Show / Hide 
Range on Protein: 186-442
Range on HMM: 4-255/259
Sequence Identity: 38% (100 aa)

KEWEALCNYEAEPsVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANatgsdYINASFITD-HDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNL
.|.. | .  .    .. ||...| .|||| .|||||. || | . ..     |||||.|    .  .  |||.|||| .||.|||||||||. ||. .|
eefkelrelkpld-tcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamv

TRLSDLGLPQCHRYWPEDGHETYHIYE---VHLVsEHIWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRgRSCPIV
   . |  .|||||||  ... ....   |.|. .    |.. ||.. .|.....|.| |....| .||| .||.....|..| ..|..  .  . ||||
tlekekgkvkchrywPerknkklkvsnrlevell-kvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPiv

VHCSGGVGRTGCYILIDLVLNKMMRGAkEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVA
||| |.||.| .| || ||. . |   |.|.  .|..||.||  .|.|| |. |   |.  
vhcsaGiGrsGvlitidvvlglierdk-efdvkeivrklreqrqgvvqtkdqyifvykail
Phosphatase Nvec_PTPRN.AA Subfamily.N5_RR.PD 208-442 35 7e-63 203.7 In-house 22-261 (265) Show / Hide 
Range on Protein: 208-442
Range on HMM: 22-261/265
Sequence Identity: 35% (87 aa)

KNVRKNRYSDVLPYDHNRVSL-RETANATGSDYINASFITDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDGH--
.. .||||...|| .. ||.| .|....  |.|||| .|  .| .. ||.||||||..|..|||.|.... | ||| ||.|..    .|..|.|.. .  
gsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedye

--ETYHIYEVHlVSEHIWCDDYLVRSFYLKNLQTsETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCF---RGRSCPIVVHCSGGVGRTGCYILIDL
  |.|   |.. |.| . ..|| ||...||.|.   .|.|. . . .||| ..|  ...||.. ..|..       .  |.||||| |.|||||.| |..
iserygdveik-veeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisi

VLNKmMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVA
 ... .|  . .|.  .| .|| .|  ||.|. |.|.   |..
avrq-lreeivvdvlkivcnlrldrGGmvqtseqyelihralc
Phosphatase Nvec_PTPRN.AA Subfamily.RC.PD 201-443 36 1.2e-61 199.7 In-house 18-285 (288) Show / Hide 
Range on Protein: 201-443
Range on HMM: 18-285/288
Sequence Identity: 36% (94 aa)

ADLGKQDKNVRKNRYSDVLPYDHNRVSL-------------------RETANATGSDYINASFITDHD-PRnpAYIATQGPLAHTVSDFWQMVWEQGVVV
.....|  |||||||||||.||| |                    ..    ||.|||||||  .  |.   |||.||||  || |||.|..|. | ||| 
ikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpe--kyiaaqGplketvddfwrmiferkvkv

IVNLTRLSDLGLPQCHRYWpEDGHETYHIYEVHLvSEHIWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEF----------RRKVN
||.| .    .| .|| |.|...|   ||.|  ..  . ||..| . |.| .  ..|.|||. . ||.. ..|  || ||...|...   .  | |..||
ivmltelkeGdrekcaeyw-eeGkrayGdvevdl-kdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsse

KCFRGRSCPIVVHCSGGVGRTGCYILIDLVLNKMmRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
|. |..||| .| .. .|. .    . .|.   | .|| .|| ||....|. .   ...|             
afknfkstpllvhcrdGsqrtGifiallallesl-eaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase Nvec_PTPRN.AA Subfamily.N14.PD 186-441 35 1.5e-61 199.3 In-house 4-270 (275) Show / Hide 
Range on Protein: 186-441
Range on HMM: 4-270/275
Sequence Identity: 35% (95 aa)

KEWEALCNYEAePSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANAtGSDYINASFITDH-DPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNL
.|.| . . ..  .. . .| ..|..|||. |||||..||| |  | ..  ..||||| |      ..  ||..|||| .|| ||||||||||| .|| |
teyeripkkre-dallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivml

TRLSDLGLPQCHRYWPEDGHETYHI-YEVHLVSEHIW--CDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVN-------KCF-
|.  . |  ....|.|.....  .. .. . |...     | .  ... || | ..| |||  . .  ||| .||  .|..|.| ..|.       .   
teeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseve

--RGRSCPIVVHCSGGVGRTGCYILIDLVLNKMmRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAV
  . .. |..|||| ||||||  || ||... .    .||||  ....|| || ..|.| ||..|  ...
svkeskPPvlvhCsaGvGrtGvlilsdlliatl-ehneeidikkvlarLrkqrmllvqtlaqykfvykvl
Phosphatase Nvec_PTPRN.AA Subfamily.N23.PD 196-443 35 1.2e-58 190.1 In-house 91-347 (350) Show / Hide 
Range on Protein: 196-443
Range on HMM: 91-347/350
Sequence Identity: 35% (87 aa)

AEPSVADLGKQDKNVRKNRYSDVlpYDHNRVSLR-ETANATGSDYINASFITDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQ
| | .  | ..    ...   .    |.||| |.  |   . .|||||... .  |  | .||||||.| |..|||.||||| . ||| ||.. . ..|.
avpqprhlqtegsGqqqgtpdsr--hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklk

CHRYWPEDGHETYHIY--EVHLVSEHiWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCF---RGRS------CPIVVH
.|||.|  || .    .| | |..   . .  | . |.  ..|  |.|...|. .|... ||  |. ||.|  .|....   |||..||| |||||| . 
cdqYwPidegetnlfgdlrvslkslr-ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilh

CSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
..  .....  |   |.|   |..|| || .||..|.....  .|| |            
CsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavle
Phosphatase Nvec_PTPRN.AA Subfamily.N1.PD 204-444 36 4.9e-57 184.7 In-house 23-266 (268) Show / Hide 
Range on Protein: 204-444
Range on HMM: 23-266/268
Sequence Identity: 36% (89 aa)

GKQDKNVRKNRYSDVLPYDHNRVSLRETANatgsDYINASFItDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDG
|...|  .||| || |||| |. |... .    ||||||.. . .  .  || |||||.||.. ||||||||    .. | .. . .  .|.|||.. .|
aklpenrglnryrdvspydhsrikleradv----dyinaslv-eleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqee

HE---TYH--IYEVHLVSEHIwCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNK--CFRGRSCPIVVHCSGGVGRTGCYIL
   ...   ..|.|.||..  . .||| . |..|.|.|||....||.  |||. ||..|. .|.|  || .  ..     |.|.||| |.||.| . |.|
eeaellleetklkvkliseer-ksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlsl

IDLVLNKMMRGAK--EIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEE
 .| .. .  .   .||   . .|| .|  ...|  | .|. .|. |   
vdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg
Phosphatase Nvec_PTPRN.AA Subfamily.N_Choan_2.PD 197-444 34 5.5e-56 180.9 In-house 9-264 (266) Show / Hide 
Range on Protein: 197-444
Range on HMM: 9-264/266
Sequence Identity: 34% (85 aa)

EPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCH
|.|  .. .  .| | ||| |.||  . || | |  .   . |||| ..   | .. .|||..|||. |...||.|.||. |  ||.| | . |  .| |
evseeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCe

RYWPEDGHETYHI--YEVHLVSEH-IWCDDYLVRSFYLKNlqTSETRTVTQFHFLSWPDLNVPTTPK------PLLEFRRKVNKCFR--GRSCPIVVHCS
|||.. .|. ..   ... ....    . |...   |..   .|||... |.. .|||  ||...||.  |.|..  .   .. |..|||| ||||||. 
rYWpaepkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcs

GGVGRTGCYILIDLVLNkMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEE
|.|| ... ..   |..|..| .|.|| .|. .|..  |.|..  ||.|          
aGvgRtGtliaiDiavr-lLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey
Phosphatase Nvec_PTPRN.AA Subfamily.N_Nematode_4.PD 198-443 33 3.8e-48 155.4 In-house 15-261 (264) Show / Hide 
Range on Protein: 198-443
Range on HMM: 15-261/264
Sequence Identity: 33% (85 aa)

PSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETAnaTGSDYINASFITDhdPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHR
|.      ..||  |||| |.|  |..|| |..       ||| ||...   | .  ||.||||| .|.|||| ||... . |.| |  | . |. .| |
ppnvtasaseknsdknryadilcidetrvvlknrd--pdndyihaswmrm--PdkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcar

YWPEDGHE--TYHIYEVHLVSEHIW-CDDYLVRSFYLKNLQ-----TSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKcfRGRSCPIVVHCSGGVG
|.||. ..  .. .|...|| ..     | ...|. . | .     .||   |  ...  |.|   |...|.... . |.|  . .. ||||||| ||||
yypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvG

RTGCYILIDLVlNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
|  .. ||.  . ..|   ||..   | .||  | . |... || | |  ..| 
rtatlvGidya-tirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase Nvec_PTPRN.AA Subfamily.N20.PD 198-443 35 1.2e-46 150.6 In-house 15-254 (257) Show / Hide 
Range on Protein: 198-443
Range on HMM: 15-254/257
Sequence Identity: 35% (87 aa)

PSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETanatgSDYINASFITDHDP-RNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCH
|   . |.|  |  |||| |.||||  || | ..      ||||||.|   .   .  ||||||||  |. |||||| |.   ||  .||  .|. .|..
pgefnsgnqpsnreknryrdilpydstrvplgks-----kdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcy

RYWPEDGHETYHIYEVHLVSEHIWC-DDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRgrSCPIVVHCSGGVGRTGCYI
|||   ..   .  .... |     . ...| | . .  |  ...| |..|  |||   |..   .... |   |..   . |.||||| |.|||| .. 
hywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshl--tgpmvvhcsagigrtgvfl

LIDLVLNKMMRGAkEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
.|.|.  ... .  ..|   | ..|.||  ||.|| |. |.   | | 
cvdvvfcaivknc-sfnimdivaqmreqrsgmvqtkeqyhfcydivle
Phosphatase Nvec_PTPRN.AA Subfamily.N_Nematode_1.PD 184-436 33 1.8e-46 149.8 In-house 2-255 (265) Show / Hide 
Range on Protein: 184-436
Range on HMM: 2-255/265
Sequence Identity: 33% (87 aa)

LNKEWEALCNYEAEPsVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETanATGSDYINASFITDH-DPrnPAYIATQGPLAHTVSDFWQMVWEQGVVVIV
| .|..|| ... |    .  |....  |||| ||   |.||| |.|   .. |||| | ...    |    .| .|.|| .|..||| ||  . |  ||
lrdefralkkfndee-kvkafkeaqeadknrykdvgcldknrvklaee--plpsdyihanyvgtptnp--krficaqaPldktiadfwymvlqekveaiv

NLTRLSDLGLPQCHRYWPEDGHETYHIYEV--------HLVSEHIWCDDYLVRSFYLKNLQ-TSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVnkcf
 | .| . |  .|. |.|    |. .. |         .| ....  |.  ..   |.     ..||.||....  |||  ||..    ||.  .|    
mlckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleav----

RGRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEF
||   ||||||| |.||||  . |...|.|.. | .  |.   |...|.||. ..| ||. | 
rgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylf
Phosphatase Nvec_PTPRN.AA PTPc_motif 341-443 38 4.8e-41 143.6 SMART 1-92 (92) Show / Hide 
Range on Protein: 341-443
Range on HMM: 1-92/92
Sequence Identity: 38% (42 aa)

TVTQFHFLSWPDL-----NVPTTPKPLLEFRRKVNKCFRGRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFE
||...|...|||      .||.  ...|||.|.|.|       ||||||| |.||||....||.....       .||  ||...|.|||.||.|..|. 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQYI

FALTAVAE
|   ...|
FCYRCILE
Phosphatase Nvec_PTPRN.AA Subfamily.R_Nematode_3.PD 201-443 23 3.3e-39 126.1 In-house 15-264 (267) Show / Hide 
Range on Protein: 201-443
Range on HMM: 15-264/267
Sequence Identity: 23% (59 aa)

ADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDhdPRNPAYIATQGPL--------AHTVSDFWQMVWEQGVVVIVNLTRLSD---
..  . .|.| ..|...|. . ..|| | .  .   .|.|.|....   | .   | ||.|.        . |.  ||.|. ...| ..| |    .   
knatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvec--pnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedg

LGLPQCHRYWPEDGHETYHIYEVHLVS---EHIWCDDYLVRSFYLkNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCfrgrSCPIVVHCSG
 .  .| .|.||.  .  .. .| .     ..   .|   |.. . ...  .. |||  .. .|..||.| .||..||  ..|.|.      |.||||| 
eeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveks----ktpvvVHCsd

GVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
|..|...   |.|. .....  ...|... ...|| ||.. ..|. .. |... .  
GisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilk
Phosphatase Nvec_PTPRN.AA Subfamily.N_Nematode_5.PD 201-442 25 1e-38 124.3 In-house 17-254 (258) Show / Hide 
Range on Protein: 201-442
Range on HMM: 17-254/258
Sequence Identity: 25% (63 aa)

ADLGKQDKNVRKNRYSDVLPYDHNRVslreT-ANATgSDYINASFITDHDPRNpAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQChRYW
.  . .||. |||. ||  .|..||      ..   ..||||| |.  | ..  .| || || .|..|||.|| .. .. .||.. ..|  ...  ..|.
etckafeknlkknrskdvkilDetrV----kltded-dsYinaskiklddlek-kliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sff

PEDgHETYHIYEVHLVSEHIWCDDYLV-RSFYLKNLQT--SETRTVTQFHFLSWPDLNVPTTPKPLLEfrRKVNKCFRGR---SCPIVVHCSGGVGRTGC
  ...|  ..  ..       .      .... |    ||   ..  |.  |.. .||.  |....|...| ..     . |.||... |.||.|  .|.
ple-tgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagt

YILIDLVLNKMMRGaKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVA
... ... .| ||..|.......|.|||..|.. .|. .. .||.    
flllsvaieqlnng-kepnideilkkirsqRpgavesliqyasvyaavl
Phosphatase Nvec_PTPRN.AA Subfamily.R_Nematode_2.PD 209-436 27 1.3e-38 124.0 In-house 29-251 (261) Show / Hide 
Range on Protein: 209-436
Range on HMM: 29-251/261
Sequence Identity: 27% (63 aa)

NVRKNRYSDVLPYDHNRVSLREtaNATGSDyINASFITDhDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDGHETYH
.  |.|| ||   .. .|      . . .. | | ..   . ..  .|||||||  |..||| ||  . |  || |..  ..|..|.| . ... ..  .
pkdkhRypdvPCkpetaveviv--dgkrvp-ihanwvpt-agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld

I--YEVHLVS-EHIWCDDYLVRSFYLKNLQT-SETRTVTQFHFLSWPDLNVPTTPKPLLefrrKVNKCFRGRSCPIVVHCSGGVGRTGCYILIDLVLNKM
... || |.|  |.  .|..  .. .   .||||| . . .||| .|| . . |     .. ...   ||||||| |.|||. .| .. . ....   ..
lgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf----eLlelvkksekPivvhCsaGiGRtmafigteylarev

MRgAKEIDIAATVEHLRDQRPHMVKTKAQFEF
| .. ....||..|.. ..|. |. .      
ea-dptieltealkelrehRwkgiqtesqlyw
Phosphatase Nvec_PTPRN.AA Subfamily.N_Nematode_6.PD 184-443 28 2.3e-35 113.5 In-house 2-250 (253) Show / Hide 
Range on Protein: 184-443
Range on HMM: 2-250/253
Sequence Identity: 28% (74 aa)

LNKEWEALCNYEAEPSVADLgkqDKNVRKNRYSDVLPYDHNRVSLRETANAtgsdYINASFITDHdPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVN
|.||...  |  .| ..  .    |.  .|||...  .|  |. | .  .     || |...  . ...  .| ||.||  |..||.|.  .||  || |
lkkeykdspneaseseataf---lkfkdrnrytniqCcdagrlkladdedf----yihanlvkis-tkprrlictqaplegtieefwkmilssgveyivm

LTRLSDLGLPQCHRYWPEDGHETYHIYEV--HLVSEHIWCDDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRrkvnKCFRGRSCPIV
  | . | ... .| ..   .. .| ..   .  ..   |  ||||      .. |   |  .|. .|||  || . .  | .     . ..    ||||
lcelvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrll----svvkkdkkPiv

VHCSGGVGRTGCYILIDLVLNKmMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE
||| ||||||  .||  .|.  .| .. ...   . .||..| . |.|. |. .||  | | 
vhCsaGvGrtGtlaliliilea-lrlpdfqgvkdllvklreerfravqtevqylyalrcvle
Phosphatase Nvec_PTPRN.AA Subfamily.N_Fungi_PTP1.PD 209-309 36 1.4e-28 91.1 In-house 45-158 (343) Show / Hide 
Range on Protein: 209-309
Range on HMM: 45-158/343
Sequence Identity: 36% (40 aa)

NVRKNRYSDVLPYDHNRVSLRE--------TANATGSDYINASFITDH---DPRNPAY--IATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQC
||||...|||.|.|| |..             ..|||||...         || .  ||||.||  || ||.... . .|||. || . .|.| .|.|||
lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekc

HRYWPEDGHETYHI
.| . . ...    
yrYWqegsydditv
Phosphatase Nvec_PTPRN.AA Subfamily.N_Nematode_egg.PD 204-439 27 1.6e-24 78.0 In-house 21-250 (257) Show / Hide 
Range on Protein: 204-439
Range on HMM: 21-250/257
Sequence Identity: 27% (62 aa)

GKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDhDPRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLglPQCHRYWPEDG
.| .  | |   |   .  || |.        |.| | ..   .|    .| .| ||  || |||.||... |  || ||.    .|. |||    |.  
aasdnylekarskrvhckessrvklelrrGqylddfihanrvkG-kpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkae

HETYHIYEVHLVSEHIWCD---DYLVRSFYLKNLQTSetRTVTQFHFLSWpDLN-VPTTPKPLlefrrKVNKCFRGRSCPIVVHCSGGVGRTGCYILIDL
.    |  | .  |   | | |   || . .   .         . |.| .     ||.| .  |  | |.||..  || .... . |.. | ...||  
seslvtvpGslrienlkvdskadplfrvtklklvGgd--deelflehwqg-dvnylsdvyspl-----rvlrklrnlskpvvvqdilGvskaatlvaiei

VLNKMMRGA-KEIDIAATVEHLRDQRPHMVKTKAQFEFALT
    .  .|  || .|.  |..  .. |             
allsllrGpitkslvlravvflrlrrrlsvesvllylfvyr
Phosphatase Nvec_PTPRN.AA Subfamily.N_Nematode_eak.PD 204-358 26 7.9e-20 62.5 In-house 21-172 (281) Show / Hide 
Range on Protein: 204-358
Range on HMM: 21-172/281
Sequence Identity: 26% (39 aa)

GKQDKNVRKNRYSDVLPYDHNRVSLRETANAtGSDYINASFITDHDpRNPAYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDG
... ..|..||  ...|.|.. | |  .       ||||| .   .     || |  .  . |  ||||| ||    || |...| .  .|.|.....  
tarleavnrnrvvkivpqdrylvrltssqln-rdGyinaslaefse-vGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt

HE-TYHIYEVHLVSEHIWCDDYLVRSFYLKnlQTSETRTVTQFHFLSWPDLNVPTT
| |..|.  .  .  . . .| . |.  .  ||  |  ...  | ....|      
evlkyGildverkeyavkrniletrllilr--kGnethrvlhykvfGwtettlpky
Phosphatase Nvec_PTPRN.AA Subfamily.N_Fungi_PTP1.PD 336-440 35 3.2e-13 40.6 In-house 209-337 (343) Show / Hide 
Range on Protein: 336-440
Range on HMM: 209-337/343
Sequence Identity: 35% (41 aa)

TSETRTVTQFHFLSWPDLNVPTTPKPLLEFRR---K-------VNKCFRGRSCPIVVHCSGGVGRTGCYILIDLVLN-------------KMMRGAKEID
||  .| |...  |.||..   |. .|.      .        .     || ||.|||| |||||| .. .| .|.|. . ||  | |  .| .|| || 
vsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrD

-IAATVEHLRDQRPHMVKTKAQFEFALTA
 ||... || |   |              
lisiivnelrkqrismvqnldqfifiYea
Phosphatase Nvec_PTPRN.AA Family.DSP.PD 259-435 14 4.9e-13 40.4 In-house 116-237 (387) Show / Hide 
Range on Protein: 259-435
Range on HMM: 116-237/387
Sequence Identity: 14% (26 aa)

QGPLAHTvSDFWQMvWEQGVVVIVNLTrlsdlglpqchrywpedghetyhiyevhlvsehiwcddylvrsfylK------NlqtsetRTVTQFHFLSWPD
|.| .  ... ..  | || .|||||                                              .      .      .   ... ....| 
lgsllaa-knlewl-kelgvtkivnlt----------------------------------------------ddkpqftk------elgikylripidD

LNVPTTPKPLLEFRRKVNKCFRgRSCPIVVHCSGGVGRTGCYILIDLVLNkmmrgaKEIDIAATVEHLRDQRPHMVKTKAQFE
|.|.  . . .. . .... .  .  ..||| .|.||.|  | . |. .      . .   ......|..||.... . .|  
hnapplenlfekaidfieegnd-skgvVlVHCkaGkgRsgtliiaYlmks------egltleealdwvrskRpgvitpnqgfl
Phosphatase Nvec_PTPRN.AA Subfamily.PTPDC1.PD 317-436 24 1.1e-10 32.7 In-house 110-219 (229) Show / Hide 
Range on Protein: 317-436
Range on HMM: 110-219/229
Sequence Identity: 24% (29 aa)

EHIWCDDYLVRSFYLKNLQTSETRTVTqFHFLSWPDLNVPTtPKPLLEFRRKVNKCFrgRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKeidiaaT
||  |   | .| .  .      . .. |.  ...| .|..  . .|.  . |.     .   | |||  | ||||  |   || .| ....       .
ehahCGagleesGfsYdpeelmrqgiy-fynfglkDygvas-leriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvyakrltaee------a

VEHLRDQRPHMVKTKAQFEF
. .|..||. ..|. | |. 
iklvrskrpksiqtreqvel
Phosphatase Nvec_PTPRN.AA Subfamily.DSP23.PD 344-433 21 5.2e-07 21.1 In-house 35-116 (128) Show / Hide 
Range on Protein: 344-433
Range on HMM: 35-116/128
Sequence Identity: 21% (19 aa)

QFHFLSWPDLNvPTTPKPLLEFRRKVNKCfRGRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKeidiaaTVEHLRDQRPHMVKTKAQ
.. .. ||   | ... . .. | |..    .  .. |||  |.||||  .   || .. .  ..      ..  .| .|.  . |. | 
tlrridipdfc-PPaleqvarlvriveea-ekkeeavgvhcalGlGrtGtllacylvkeeglaadd------aiaevrkrrkGsietveq
Phosphatase Nvec_PTPRN.AA Subfamily.TPIP.PD 352-410 31 2.6e-06 18.4 In-house 12-70 (245) Show / Hide 
Range on Protein: 352-410
Range on HMM: 12-70/245
Sequence Identity: 31% (19 aa)

DLNVPTTpKPLLEFRRKVNKCFRGRSC-PIVVHCSGGVGRTGCYILIDLVLNKMMRGAKE
| ||||  . |. | ..|.. .       ...|| || ||||  .   |.  .... |.|
dhnvPtl-eelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaee
Phosphatase Nvec_PTPRN.AA Subfamily.CDC14.PD 363-432 29 1e-05 16.6 In-house 188-247 (258) Show / Hide 
Range on Protein: 363-432
Range on HMM: 188-247/258
Sequence Identity: 29% (20 aa)

LEFRRKVNKCfrgrSCPIVVHCSGGVGRTGCYILIDLVLNKMmrgakeIDIAATVEHLRDQRPHMVKTKA
.| . ..|.    .  |.|||  |.||||. |   |. .        .  | |. .||  || .| ..  
kkfleiteka----eGaiavhCkaGLGrtgtligcylikhyr------ftaaetiawlriarPGsvigpq
Sequence
Name Sequence Type Origin Length Description Download
Nvec_PTPRN.AA Protein None 454 None Fasta, JSON
Nvec_PTPRN.NA RNA None 1362 None Fasta, JSON
Nvec_PTPRN.AA.PD_183-446 Protein Phosphatase Domain None 264 None Fasta, JSON