nvec_CDC14A
Species: N.vectensis
Alias: nvec_CDC14A
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: CDC14
Protein domain

Protein domains of nvec_CDC14A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_CDC14A.AA Subfamily.CDC14.PD 78-329 57 3.3e-110 359.4 In-house 7-257 (258) Show / Hide
Range on Protein: 78-329
Range on HMM: 7-257/258
Sequence Identity: 57% (145 aa)

KKIVHFTSTDSRKRANAACLIGSYAVIYLKKSADEIYQTLNTgCNPPYLPFRDASFGACSYNLSILDVLSGLQKALQNDFFNLDTFDVHEYEYYERVENG
..|   |.|| . |.|||.||| .||  |. . ..   .|.| ..||. ||||||.    |.| .  |.||  .|| | | .. |||.  |...||||||
qriyfctgtdmqvrsnaaaliglfavwclnmtdeqaiacldt-akppfapfrdasyapvlyklhvryvisgayqallngfidvhtfdldtydhferveng

DFNWIVPGKFLAFSGPHNKSRIKDGYPLHAPEAYIPYFKKHNISTVVRLNKKLYDAQRFTDHGIEHYDLFFIDGSVPSDMIVRRFLTIAENAKGGIAIHC
||  |.| ||.|..||||||...|||.|.|||... ||.|.|..|.||||||||||..|||.|..|.|||||||.||||.|...||.|.|.|.| ||.||
dfttiipnkfialagphnkskvedGytllaPeklleyfrknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleitekaeGaiavhC

KAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPGSIIGPQQNFCEEKQAS
|||||||||||.|||.|||||||||.|.|||..||||.|||||....||||.
kaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtylvekqad

Phosphatase nvec_CDC14A.AA Family.DSP.PD 79-327 33 3.6e-52 169.6 In-house 8-241 (387) Show / Hide
Range on Protein: 79-327
Range on HMM: 8-241/387
Sequence Identity: 33% (83 aa)

KIVHFTSTDSRKRANAACLIGSYAVIYLKKSaDEIYQTLNTGCNPPYLPFRDASFGACSYNLSILDVLSGLQKALQNDFFNLDTFDVHEYEYYERVENGD
.|   | || . |.||| ||| .||  |..  ||      .   |...|||||| .  ...|.   | || . |..| | .  |||...|. .||||||.
riyfctGtdmqvrsnaaaliGlfavwclnmt-deqaiacldtvkpkfapfrdasyapvlaklhvryvisgakqaelngfidvhtfdldtydhfervengk

FNWIVPgkflafsgphnksRIKDGYPLHApeAYIPYFKKHNISTVVRLNkklYDAQRFTD-HGIEHYDLFFIDGSVPSDMI-VRRFLTIAEN---AKGGI
.. | |             .. .|..|.|     . .|..... .|.|.   .| ..||  .||........|...|.  . . ... . |..|| ...|
pseilp-------------hlylgsllaa--knlewlkelgvtkivnlt---ddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvV

AIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPgSIIGPQQNFCEEKQ
||||.||.||||..||||....|. |.. |.| .|| ..| |.|.| .. .   
lVHCkaGkgRsgtliiaYlmksegltleealdwvrskRp-gvitpnqgflkqlk

Phosphatase nvec_CDC14A.AA Subfamily.PRL.PD 209-327 35 4.8e-21 66.7 In-house 15-137 (140) Show / Hide
Range on Protein: 209-327
Range on HMM: 15-137/140
Sequence Identity: 35% (43 aa)

EAYIPYFKKHNISTVVRLNKKLYDAQRFTDHGIEHYDLFFIDGSVPSDMIVRRFLTIA-----ENAKGGIAIHCKAGLGRTGTLIACYLMKHyRFTAAES
| .|  .||.|...|||  .  |||... ..|||  || | ||.||.. .|...|..      |. |  .|.|| |||||.  |.|  |. ...  ... 
ekfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyeda

IGWLRVCRPGSIIGPQQNFCEEKQ
..|  | |.|   | .| |. .  
vefirekrrgainskqlkflekyk

Phosphatase nvec_CDC14A.AA Subfamily.PTPDC1.PD 231-320 42 3e-18 57.7 In-house 125-216 (229) Show / Hide
Range on Protein: 231-320
Range on HMM: 125-216/229
Sequence Identity: 42% (38 aa)

YDAQRFTDHGIEHYDLFFIDGSVPSDMIVRRFLTIAENA--KGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPGSIIGPQQ
||   .  .|| .|   . | .|.|   .     ... |  .| ||.|| ||||||| ||||||. . |.||.|.|  .|  || ||.|   
YdpeelmrqgiyfynfglkDygvasleriLdivkvvdfaleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreq

Phosphatase nvec_CDC14A.AA Subfamily.DSP23.PD 254-320 41 4.4e-17 54.0 In-house 47-116 (128) Show / Hide
Range on Protein: 254-320
Range on HMM: 47-116/128
Sequence Identity: 41% (29 aa)

PSDMIVRRFLTI---AENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPGSIIGPQQ
|.   | |.. |   ||. .. ...||  ||||||||.||||.|. ...|...|  .|  |.|||   .|
PaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietveq

Phosphatase nvec_CDC14A.AA Subfamily.PTPMT1.PD 215-313 28 4.9e-15 47.2 In-house 21-129 (146) Show / Hide
Range on Protein: 215-313
Range on HMM: 21-129/146
Sequence Identity: 28% (31 aa)

FKKHNISTVVRLNKKLY------DAQRFTDHGIEHYDLFFIDGSV-PSDMIVRR---FLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESI
..|.|. .|| ||.           . ....|.|.. |  .|    ||   ...   |.    . .  . .||||| .| .||.||||||...... |..
vekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeav

GWLRVCRPG
  |. .|| 
kflkkkRpq

Phosphatase nvec_CDC14A.AA Subfamily.PTEN.PD 267-306 41 1.2e-11 36.1 In-house 91-131 (305) Show / Hide
Range on Protein: 267-306
Range on HMM: 91-131/305
Sequence Identity: 41% (17 aa)

ENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAA-ESIGW
|. .  .|.||||| ||||..|..||.|.  .. | |.. .
edksnVvavHCkaGkGRtGvmicayLlksgikksadealai

Phosphatase nvec_CDC14A.AA Subfamily.DSP11.PD 228-312 24 3.3e-11 34.8 In-house 32-123 (141) Show / Hide
Range on Protein: 228-312
Range on HMM: 32-123/141
Sequence Identity: 24% (22 aa)

KKLYDAQRFTDHGIEHYDLFFIDGSVPSDMIVRRFLTI-------AENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRP
.. |. . .||.|.... |.    .||.. .|..| .         .. .  |..||  |. ||| ||  ||...  . . ..|  .  .| 
dryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearG

Phosphatase nvec_CDC14A.AA Subfamily.RNGTT.PD 216-315 23 5.5e-11 33.9 In-house 15-124 (140) Show / Hide
Range on Protein: 216-315
Range on HMM: 15-124/140
Sequence Identity: 23% (25 aa)

K--KHNISTVVRLN--KKLYDAQRFTDHGIEHYDLFF-IDGSVPSDMIVRRFLTIAEN-----AKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIG
|  |...  |. |   .. ||.. ....|...  |     |  |.   .. |... ..      .  |..||  |  ||| ||..||.....  ...  .
ktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaava

WLRVCRPGSI
  .||  |  
lfakarppGi

Phosphatase nvec_CDC14A.AA DSPc 266-308 25 3e-10 37.55 Pfam 81-128 (151) Show / Hide
Range on Protein: 266-308
Range on HMM: 81-128/151
Sequence Identity: 25% (12 aa)

AENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWL-----R
... .| . .||.||. |...|...|||| ..... | .  .     .
CRQKGGKVLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMK

Phosphatase nvec_CDC14A.AA Subfamily.DSP1.PD 259-323 29 3.7e-10 31.6 In-house 68-130 (139) Show / Hide
Range on Protein: 259-323
Range on HMM: 68-130/139
Sequence Identity: 29% (19 aa)

VRRFLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgSIIGPQQNFC
.  |.  .....| . .||.||. |. |..  ||||. ...  |.  ...  |  ||| |  .| 
aidfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrr--siisPnfgfv

Phosphatase nvec_CDC14A.AA Subfamily.DSP10.PD 262-323 32 9e-10 30.2 In-house 73-132 (141) Show / Hide
Range on Protein: 262-323
Range on HMM: 73-132/141
Sequence Identity: 32% (20 aa)

FLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPgsIIGPQQNFC
|.  | .  . . .||.||. |. |..  |.||| . .  |.  ...  ||  || |  || 
fieearkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrP--iisPnlnfm

Phosphatase nvec_CDC14A.AA Subfamily.DSP12.PD 261-324 26 2.5e-09 29.0 In-house 72-133 (143) Show / Hide
Range on Protein: 261-324
Range on HMM: 72-133/143
Sequence Identity: 26% (17 aa)

RFLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgSIIGPQQNFCE
||.  . . .| . .||.||. |  |... ||||....   . .  ..  .  . | | ..| |
rFieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekk--keiepNegFle

Phosphatase nvec_CDC14A.AA Subfamily.DSP19.PD 261-324 28 2.5e-09 28.7 In-house 70-131 (139) Show / Hide
Range on Protein: 261-324
Range on HMM: 70-131/139
Sequence Identity: 28% (18 aa)

RFLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPgsIIGPQQNFCE
|.  | ...| . .||.||  |. ...  ||||. . .  ...  .|  ||   | | . |.. 
dFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearp--cikPneGFik

Phosphatase nvec_CDC14A.AA Subfamily.DSP14.PD 266-324 30 7.8e-09 27.3 In-house 74-130 (138) Show / Hide
Range on Protein: 266-324
Range on HMM: 74-130/138
Sequence Identity: 30% (18 aa)

AENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPgsIIGPQQNFCE
.....| . .||.||  |  .|.  ||||. . . .|.  ... .||  || | . | .
vkkkgGktlvhCvaGvsRsAslvlaylmkyeklsLreayklvksaRp--iirPnvGFwk

Phosphatase nvec_CDC14A.AA Subfamily.DSP3.PD 222-322 27 8.3e-09 27.1 In-house 41-138 (148) Show / Hide
Range on Protein: 222-322
Range on HMM: 41-138/148
Sequence Identity: 27% (27 aa)

TVVRLNKKLYDAQRFTDHGIEHYDLFFIDGSVPSDMIVRrFLTIA-ENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgsIIGPQQ
. |. ... |.    . .|.|  |.. .| |   .  .  |.  | .. .| . .||..|. |. ||.  ||| . ..|. |.|   |  ||.| . |  
lkvdtdaefYkdleikylGvevsDvpefdlskyfeeaad-fidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkr---eilPne

NF
  
Gf

Phosphatase nvec_CDC14A.AA Subfamily.Slingshot.PD 261-325 28 1e-08 26.7 In-house 70-132 (139) Show / Hide
Range on Protein: 261-325
Range on HMM: 70-132/139
Sequence Identity: 28% (18 aa)

RFLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgSIIGPQQNFCEE
.|.. | ...  . .||| |. |. . .  | ||.|...  |.. ...  |  ||| | ..| . 
kfiekakekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerr--siikpnkgflkq

Phosphatase nvec_CDC14A.AA Subfamily.LRR-DSP.PD 269-322 39 4.6e-08 24.6 In-house 76-127 (137) Show / Hide
Range on Protein: 269-322
Range on HMM: 76-127/137
Sequence Identity: 39% (21 aa)

AKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPgsIIGPQQNF
|||. |||.||. |. ||. .||||. ...  |..      ||   | |.. | 
ekggvlihcragvsrsatlviaylmkknslkfkealdlvikkrp--riypnrgf

Phosphatase nvec_CDC14A.AA Subfamily.TPIP.PD 266-303 43 6.4e-08 24.1 In-house 33-71 (245) Show / Hide
Range on Protein: 266-303
Range on HMM: 33-71/245
Sequence Identity: 43% (17 aa)

AENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAE-S
|.. .  .||||| | |||||.. ..|..   |. || |
akdlenvvaihckGGkgrtGtivcalliaseifltaees

Phosphatase nvec_CDC14A.AA Subfamily.DSP6.PD 261-323 29 8.7e-08 23.6 In-house 72-132 (141) Show / Hide
Range on Protein: 261-323
Range on HMM: 72-132/141
Sequence Identity: 29% (18 aa)

RFLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgSIIGPQQNFC
.|.  | ..| .. .|| ||. |. |.. .||||.. ..  ..  ...  .  | | |  || 
efidearskkskvlvhclaGvsrsvtvtlaylmkklalslndaydlvkkkk--snisPnfnfm

Phosphatase nvec_CDC14A.AA Subfamily.DSP8.PD 262-324 30 9.3e-08 23.8 In-house 73-133 (143) Show / Hide
Range on Protein: 262-324
Range on HMM: 73-133/143
Sequence Identity: 30% (19 aa)

FLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgSIIGPQQNFCE
|.  |..|.| . .|| ||  |. |.. .|.||. ...  |.  ...  |  . | |. || .
fidkarsangkvlvhclaGisrsatvaiayimktlemsldeayrfvkekr--ptispnlnflg

Phosphatase nvec_CDC14A.AA Subfamily.N_Nematode_6.PD 251-289 43 2e-07 22.3 In-house 165-204 (253) Show / Hide
Range on Protein: 251-289
Range on HMM: 165-204/253
Sequence Identity: 43% (16 aa)

GSVPSDM-IVRRFLTIAENAKGGIAIHCKAGLGRTGTLIA
|| ..    |.|..  . |  | .|| ||.||||||.   
hGvPdsflsalrllsvvkkdkkPivvhCsaGvGrtGtlal

Phosphatase nvec_CDC14A.AA Subfamily.N_Nematode_1.PD 251-293 39 2.3e-07 22.0 In-house 177-219 (265) Show / Hide
Range on Protein: 251-293
Range on HMM: 177-219/265
Sequence Identity: 39% (17 aa)

GSVPSDMIVRRFLTIAENAKGGIAIHCKAGLGRTGTLIACYLM
|  | |. .  .|. ... || |..|| ||.|||||..|  ..
GvPpadlaalelleavrgskgPivvhCsaGiGrtGtivaieyi

Phosphatase nvec_CDC14A.AA Subfamily.N13.PD 250-293 32 5.3e-07 21.0 In-house 167-214 (259) Show / Hide
Range on Protein: 250-293
Range on HMM: 167-214/259
Sequence Identity: 32% (16 aa)

DGSVPSD---M--IVRRFLTIAEnAKGGIAIHCKAGLGRTGTLIACYLM
| .|||    .  .|..  ....  .| |..|| ||.||.|.||. . .
dhgvPssaaelvqfvaevrllqt-dagPivvhcsaGiGrsGvlitidvv

Phosphatase nvec_CDC14A.AA Subfamily.N12.PD 259-292 35 1.2e-06 19.4 In-house 188-221 (270) Show / Hide
Range on Protein: 259-292
Range on HMM: 188-221/270
Sequence Identity: 35% (12 aa)

VRRFLTIAENAKGGIAIHCKAGLGRTGTLIACYL
.. . .. |. .  ...|| || |||||.||  .
ielvrelqesedaPlvvhCsaGvGrtGtiiaidy

Phosphatase nvec_CDC14A.AA Subfamily.RB.PD 267-294 48 1.3e-06 19.6 In-house 190-218 (261) Show / Hide
Range on Protein: 267-294
Range on HMM: 190-218/261
Sequence Identity: 48% (14 aa)

ENAKGGIAIHCKAGLGRTGTLIACY-LMK
. .|. | .|| ||.||||| ||   |..
kaskkPivvHCsaGvGRtGtfialdrllq

Phosphatase nvec_CDC14A.AA Subfamily.DSP15.PD 268-322 26 2.7e-06 19.0 In-house 76-128 (138) Show / Hide
Range on Protein: 268-322
Range on HMM: 76-128/138
Sequence Identity: 26% (14 aa)

NAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRpgSIIGPQQNF
.| . .|| ||. |. ||.. |.|    ..  ...  ....|  |. .|   |  
leggnvlvhclaGisrsvtlvvayimtvtelswedalkavkaar--svanPnvGf

Phosphatase nvec_CDC14A.AA Subfamily.STYXL1.PD 261-324 20 3.3e-06 19.0 In-house 74-135 (143) Show / Hide
Range on Protein: 261-324
Range on HMM: 74-135/143
Sequence Identity: 20% (13 aa)

RFLTIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPGsiIGPQQNFCE
.|.   .. .  . .  . |. |. ..|..||| ....|  ..   |. |..   . |...| |
qfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkcken--vkPnrafve

Phosphatase nvec_CDC14A.AA Subfamily.R_Nematode_2.PD 234-293 25 5.6e-06 17.4 In-house 155-216 (261) Show / Hide
Range on Protein: 234-293
Range on HMM: 155-216/261
Sequence Identity: 25% (16 aa)

QRFTDHGIEHYDL-FFIDGSVPSD-MIVRRFLTIAENAKGGIAIHCKAGLGRTGTLIACYLM
..|. . ..||    . |  ||   . .   | .. ...  | .|| ||.|||...|.   .
gkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksekPivvhCsaGiGRtmafigteyl

Phosphatase nvec_CDC14A.AA Subfamily.RK.PD 259-293 41 5.8e-06 17.3 In-house 187-222 (267) Show / Hide
Range on Protein: 259-293
Range on HMM: 187-222/267
Sequence Identity: 41% (15 aa)

VRRFLTIAEN-AKGGIAIHCKAGLGRTGTLIACYLM
.||  .  |.  .| | .|| || ||.|| ||.  .
irrvkksqeeeeeGrivvhClaGaGrsGtfiaidiv

Phosphatase nvec_CDC14A.AA Subfamily.R_Nematode_3.PD 262-320 25 6.7e-06 17.2 In-house 190-254 (267) Show / Hide
Range on Protein: 262-320
Range on HMM: 190-254/267
Sequence Identity: 25% (16 aa)

FLTIAENAKGGIAIHCKAGLGRTGTLIA----CYLMKHYR--FTAAESIGWLRVCRPGSIIGPQQ
. ..|. |  . .||..| .|..|| |    . |. . .  .. .. |  || .|.| |  ... 
likfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtele

Phosphatase nvec_CDC14A.AA DSPc 193-327 18 1e-05 4.16 SMART 1-172 (172) Show / Hide
Range on Protein: 193-327
Range on HMM: 1-172/172
Sequence Identity: 18% (33 aa)

PHNKSRIKDGYPLHAPEAY---IPYFKKHNISTVVRLNK-------------------KLYDAQRFTDHGIEHYDL-------FFIDGSVPSDMIVRRFL
.  .   .  |   .| .     . .|||||  |. . .                    .|  . |.  .| . |        .. .  ..    | .|.
GPSEITPH-LYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFI

TIAENAKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWL-----RVCRPGSIIGPQQNFCE-----EKQ
  ... .| . .||.||. |..||...|||| . ... ...  .     .  |  .|| |  ||       |..
HDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRR-CPIICPNFNFWHQLCEWERK

Sequence
Name Sequence Type Origin Length Description Download
nvec_CDC14A.AA Protein None 521 None Fasta, JSON
nvec_CDC14A.NA RNA None 1563 None Fasta, JSON
nvec_CDC14A.AA.PD_193-329 Protein Phosphatase Domain None 137 None Fasta, JSON