Gene nvec_DUSP11
nvec_DUSP11
Species: N.vectensis
Alias: nvec_DUSP11
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_DUSP11.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP11.PD | 47-184 | 61 | 1.6e-68 | 219.7 | In-house | 2-140 (141) | Show / Hide |
Range on Protein: 47-184 Range on HMM: 2-140/141 Sequence Identity: 61% (86 aa) ENERFTPTDLIEQLAQREMKLGLVLDFTFTTRYYDPREFTAEGIIYKKMMCAGHVIPKKKDIKRFEDEVKNFLE-NDKTGSLVGIHCTHGVNRTGYMVCR |.|||.|.||.|.|.....|||||.|.| |.|||...|.|.||. |||..|.||..|.|.|.|.|...||.||| |.....|.|.|||||||||||..|| eeerfapedlleklqeknkklGLvidltntdryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCr YLIDCCGYEPEKAIEAFNQARGHPLERENYLEDLKKRLK ||||..||.||.|||||..||||.||||||||||||. | ylidvegyspedaieafeearGhslerenyledLkklak |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.RNGTT.PD | 48-185 | 41 | 1.2e-37 | 119.5 | In-house | 2-139 (140) | Show / Hide |
Range on Protein: 48-185 Range on HMM: 2-139/140 Sequence Identity: 41% (57 aa) NERFTPTDLIEQLAQREMKLGLVLDFTFTTRYYDPREFTAEGIIYKKMMCAGH-VIPKKKDIKRFEDEVKNFLEnDKTGSLVGIHCTHGVNRTGYMVCRY .|.|.|. |.. | ... |||||.|.| |.|||| .|.. ||. |.|. |.|. . |.|...| | ||.||. .| ....|.||||| ||||.... | eeafepemlksylktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflk-kkPdevigvhCthGfnrtGflivay LIDCCGYEPEKAIEAFNQARGHPLERENYLEDLKKRLKD |.. .. |.|.. | .|| . .|.||..| || .| LvekedwsveaavalfakarppGiykedylkelfkryed |
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| Phosphatase | nvec_DUSP11.AA | Family.DSP.PD | 63-184 | 24 | 2.7e-21 | 67.0 | In-house | 129-245 (387) | Show / Hide |
Range on Protein: 63-184 Range on HMM: 129-245/387 Sequence Identity: 24% (31 aa) REMKLGLVLDFTfttryYDPREFTA-EGIIYKKMMCAGHVIPKKKDIkrFEDEVKnFLENDK-TGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIE .| . ... | .|. .|| .|| | .... | |. . || .. |.|... ... | .||..|..|.| ... ||. . |.. |.|.. kelgvtkivnlt-----ddkpqftkelgikylripidDhnapplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleeald AFNQAR-GHPLERENYLEDLKKRLK ....| |. ....|. ||. .| wvrskRpgvitpnqgflkqlkdlek |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.PTEN.PD | 96-167 | 26 | 1.5e-12 | 38.2 | In-house | 66-137 (305) | Show / Hide |
Range on Protein: 96-167 Range on HMM: 66-137/305 Sequence Identity: 26% (19 aa) MCAGHVIPKKKDIKRFEDEVKNFLENDKTgSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPE-KAIEAFNQARG . | |. . .... ..|...|..||. | .|| | ||| |.| ||. . .. . .|.. ....| pfdDhnpptleLleeivedvdkwLkedks-nVvavHCkaGkGRtGvmicayLlksgikksadealaiydekRt |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.TPIP.PD | 93-163 | 32 | 3.9e-12 | 37.0 | In-house | 6-76 (245) | Show / Hide |
Range on Protein: 93-163 Range on HMM: 6-76/245 Sequence Identity: 32% (23 aa) KKMMCAGHVIPKKKDIKRFEDEVKNFLENDKTgSLVGIHCTHGVNRTGYMVCRYLIDCCGYE-PEKAIEAFN ...| | .|. ... | |||..|..|. .| ||| | .||| .|| .|| .. |.... | srimiddhnvPtleelvvftkevkewlakdle-nvvaihckGGkgrtGtivcalliaseifltaeesldyfg |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP23.PD | 76-171 | 25 | 1.6e-10 | 31.9 | In-house | 21-112 (128) | Show / Hide |
Range on Protein: 76-171 Range on HMM: 21-112/128 Sequence Identity: 25% (24 aa) TTRYYdPREFTAEGIIYKKMMCAGHVIPKKKDIKRFEDEVKnflENDKTGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARGHPLE ||. | . .|... .... . | . ..|. |. | .| . ||.|| |. ||| .. ||. |. ..|| . |.| ttega-pyseaapsltlrridipdfcPPaleqvarlvrive---eaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsie |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.CDC14.PD | 49-159 | 20 | 3.9e-10 | 30.5 | In-house | 132-232 (258) | Show / Hide |
Range on Protein: 49-159 Range on HMM: 132-232/258 Sequence Identity: 20% (23 aa) ERFTPTDLIEQLAQREMKLGLVLdftfTTRYYDPREFTAEGIIYKKMMCAGHVIPKKKDIKRFEDEVKNFlendkTGSlVGIHCTHGVNRTGYMVCRYLI . .| |.| ...... . | . || ..||..|. .. .. . .|... .|.| . . . .|. . .|| |. |||... ||| tllaPeklleyfrknnvttivrL----nkklYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-----eGa-iavhCkaGLGrtgtligcyli DCCGYEPEKAI ... . .| khyrftaaeti |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.PRL.PD | 77-180 | 25 | 2.5e-09 | 27.8 | In-house | 34-137 (140) | Show / Hide |
Range on Protein: 77-180
Range on HMM: 34-137/140
Sequence Identity: 25% (25 aa)
TRYYDPREFTAEGIIYKKMMCAGHVIPKKKDIKRFEDEVKNFLENDkTGSLVGIHCTHGVNRTGYMVCRYLIDcCGYEPEKAIEAFNQARGHPLERE--N
|| .. .||| . .. . | |. .... . .|. ... ..| |..|| |. |. .|. ||. .| ..|.|.| . |.... ..||. |
epsydaeklkeegievldlafddGavPpkevvdeWlellkekfkee-pkstvavhcvaGlGraPvlvalalie-aGmkyedavefirekrrgainskqlk
YLEDLK
flekyk
|
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| Phosphatase | nvec_DUSP11.AA | Subfamily.PTPMT1.PD | 73-177 | 17 | 1.1e-08 | 25.8 | In-house | 36-138 (146) | Show / Hide |
Range on Protein: 73-177 Range on HMM: 36-138/146 Sequence Identity: 17% (18 aa) FTFTTRYYDPREFTAEGIIYKKMMCAGHVipKKKDIKRFEDEVKNFLENDKTGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARGHPLER . .. .|....|. . .. .. . . .. |. |. . . || | .|| | | . .| ||. . ||.|...... | . . . yelkalansteewkklGveqlqlatvDft--eapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlk ENYLE .. .. skqwr |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.PTPDC1.PD | 80-173 | 24 | 1.6e-08 | 25.0 | In-house | 125-214 (229) | Show / Hide |
Range on Protein: 80-173 Range on HMM: 125-214/229 Sequence Identity: 24% (22 aa) YDPREFTAEGIIYKKMMCAGHVIPKkkdIKRFEDEVKNFLENDkTGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARGHPLERE ||| |. .||.. .. . . . ..| | || . . ...|| | ||| ... ||. ...|.||. . | .. YdpeelmrqgiyfynfglkDygvas---leriLdivkvvdfal-eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtr |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP12.PD | 105-180 | 28 | 6.4e-08 | 23.5 | In-house | 60-136 (143) | Show / Hide |
Range on Protein: 105-180 Range on HMM: 60-136/143 Sequence Identity: 28% (22 aa) KKDIKRFEDEVKNFLENDK-TGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARGHPLERENYLEDLK ..|. .. ||. .|.|. .. | .||. || | .| ||. . . |||... .... . |..|| || eedlLshldeavrFieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkkeiepNegFleQLk |
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| Phosphatase | nvec_DUSP11.AA | DSPc | 125-181 | 19 | 1.6e-07 | 28.08 | Pfam | 85-151 (151) | Show / Hide |
Range on Protein: 125-181 Range on HMM: 85-151/151 Sequence Identity: 19% (13 aa) GSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAF-----NQAR-GHPLERENYLEDL----KK | | .||..|..|.......||.. .. . |.. . .| | .. .. |.. | .. GGKVLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP10.PD | 68-153 | 27 | 2.1e-07 | 21.6 | In-house | 29-109 (141) | Show / Hide |
Range on Protein: 68-153 Range on HMM: 29-109/141 Sequence Identity: 27% (23 aa) GLVLDFTFTTryydPREFTAEGII-YKKMMCAGHvipKKKDIKRFEDEVKNFLEN-DKTGSLVGIHCTHGVNRTGYMVCRYLIDCCGY ||. | .. | .|. .|.. ||.. .|...|. .| .|.|. |.|| | .||. |. |. .| |.. . kyvlnvttsv----Pnffeekglvrykripvsds---gkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayvmkhlsl |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP19.PD | 105-166 | 28 | 1.1e-06 | 19.3 | In-house | 58-120 (139) | Show / Hide |
Range on Protein: 105-166 Range on HMM: 58-120/139 Sequence Identity: 28% (18 aa) KKDIKRFEDEVKNFLENDKTG-SLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQAR .... .. .|. .|.|. .. | .|| || |. .| ||. . |||.| .|| etkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrear |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP15.PD | 87-167 | 27 | 3e-06 | 18.0 | In-house | 42-120 (138) | Show / Hide |
Range on Protein: 87-167 Range on HMM: 42-120/138 Sequence Identity: 27% (22 aa) AEGIIYKKMMCAGHviPkKKDIKRFEDEVKNFLENDK-TGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARG |.| |. .. | | ..|...| .| .|. . . |. | .|| |. |. .| |.. .. |.|..| ..|| ledikylcikaads--P-dqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimtvtelswedalkavkaars |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.DSP1.PD | 104-165 | 32 | 4.7e-06 | 17.4 | In-house | 57-119 (139) | Show / Hide |
Range on Protein: 104-165 Range on HMM: 57-119/139 Sequence Identity: 32% (20 aa) KKKDIKRFEDEVKNFLEN-DKTGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQA ||.||. . .|. .|... |.| | .|| |. |. .| ||. .. |.| | .| kkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqr |
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| Phosphatase | nvec_DUSP11.AA | Subfamily.LRR-DSP.PD | 105-181 | 25 | 5.3e-06 | 17.1 | In-house | 57-133 (137) | Show / Hide |
Range on Protein: 105-181 Range on HMM: 57-133/137 Sequence Identity: 25% (20 aa) KKDIKRFEDEVKNFLENDKTGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARGHPLERENYLEDLKK . || .. .|. |... . | ||| || |. .| ||. . ..|.. . | . . .|..||| eadiyqhfkemnafidegrekggvlihcragvsrsatlviaylmkknslkfkealdlvikkrpriypnrgfldqlkk |
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| Phosphatase | nvec_DUSP11.AA | PTPc_motif | 88-185 | 13 | 8e-06 | 17.01 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 88-185 Range on HMM: 1-92/92 Sequence Identity: 13% (14 aa) EGIIYKKMMCAGH-----VIPKKKDIKRFEDEVKNFLENDKTGSLVGIHCTHGVNRTGYMVCRYLIDCCGYEPEKAIEAFNQARGHPLERENYLEDLKKR . | . | .|. ..| .| ..|.. . .|| .|..||| ... ... .. .. .... . | . . | . . TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ-VDIFQTVKEMRKQRPGMVQTEEQYIFCYRC LKD . . ILE |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_DUSP11.AA | Protein | None | 240 | None | Fasta, JSON |
| nvec_DUSP11.NA | RNA | None | 720 | None | Fasta, JSON |
| nvec_DUSP11.AA.PD_47-185 | Protein Phosphatase Domain | None | 139 | None | Fasta, JSON |