nvec_DUSP15
Species: N.vectensis
Alias: nvec_DUSP15
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP15
Protein domain

Protein domains of nvec_DUSP15.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_DUSP15.AA Family.DSP.PD 3-143 31 7.2e-37 118.8 In-house 105-248 (387) Show / Hide
Range on Protein: 3-143
Range on HMM: 105-248/387
Sequence Identity: 31% (46 aa)

NGMNKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDNANP--LREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICA
.....|.|.||||. .. |. |.|.|...|.|... |. .    ...| | .|.  |.. ..|  .|...|.||....... . |||| ||..||.|...
gkpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtlii

AYIMTITELSWRQTLQAIRANRS-IANPNYGFKRQLQDFYNKHL
||.|    |.  ..|. .|  |. ...||.||..||.|.... |
aYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekekl

Phosphatase nvec_DUSP15.AA Subfamily.DSP15.PD 4-140 67 4.3e-79 254.4 In-house 1-137 (138) Show / Hide
Range on Protein: 4-140
Range on HMM: 1-137/138
Sequence Identity: 67% (92 aa)

GMNKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDNANPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYI
||||..||||.||.||.||.|||.|..|||||||||.|.||.|||.|.||.|||||||||. ||.|.|.|||.||....|.||||.||||||.|...|||
gmnkvlpGlyvGnfrdakdkeqleenkithilsihdsakplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayi

MTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFYN
||.|||||...|.|..|.||.||||.||.||||.|..
mtvtelswedalkavkaarsvanPnvGfrrqlqefek

Phosphatase nvec_DUSP15.AA DSPc 4-141 27 1.5e-42 148.59 SMART 1-172 (172) Show / Hide
Range on Protein: 4-141
Range on HMM: 1-172/172
Sequence Identity: 27% (48 aa)

GMNKIIPGLYLGNIRDSK--DAEQLQEHNITHILSIHDNAN------------------PLREDIMYKCIH-AAD-------SPDQDLMPFFQECIEFIH
|. .| |.||||. ...   ....|..|||||...  .. .                  .   .. |..|    |       .. ... ..| |...|||
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

SCRVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAI-----RANR-SIANPNYGFKRQLQDFYNK
.|| |  ..|||| |||||| |.|.||.|    .|..  . ..     . .| .| .|| .|..||.....|
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK

Phosphatase nvec_DUSP15.AA Subfamily.DSP12.PD 5-140 35 3.8e-41 131.7 In-house 2-140 (143) Show / Hide
Range on Protein: 5-140
Range on HMM: 2-140/143
Sequence Identity: 35% (50 aa)

MNKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDNAN---PLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAA
...| ||||||.... .. |.|.| .|||.||.  ..      ... ..| |...|.|..||. ...|...||.... || . |||| ||.||| ||..|
vseilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA

YIMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFYN
|.|  ..|| .. |..... .. ..|| || .||. |..
YlmkkeklslekAlklvkekkkeiepNegFleQLklfek

Phosphatase nvec_DUSP15.AA Subfamily.DSP19.PD 6-138 37 1e-39 126.8 In-house 3-136 (139) Show / Hide
Range on Protein: 6-138
Range on HMM: 3-136/139
Sequence Identity: 37% (50 aa)

NKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDN-ANPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIM
.. | |||| .   .| |.|....|||||..  .  |   .|. ||.|.  | |...|. ...|...||.. | |.   |||| ||.|||...  ||.|.
aevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylm

TITELSWRQTLQAIRANRSIANPNYGFKRQLQDF
 .||| ...|. .|..|  ..|| || .||... 
kdeelslekalekvrearpcikPneGFikqLkey

Phosphatase nvec_DUSP15.AA Subfamily.DSP1.PD 6-139 36 1.4e-37 120.1 In-house 3-137 (139) Show / Hide
Range on Protein: 6-139
Range on HMM: 3-137/139
Sequence Identity: 36% (49 aa)

NKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDN-ANPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIM
..|.. ||||   .. . ..|.|..||..| .  .  |  .|   ||.|.  |....|.. .|.| |.||.|.. |.   |||| ||||||.||. ||.|
veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm

TITELSWRQTLQAIRANRSIANPNYGFKRQLQDFY
. .... ..  . .. .||| .||.|| .||  | 
kekkvrleeafefvkqrrsiisPnfgfvgqLlefe

Phosphatase nvec_DUSP15.AA Subfamily.DSP6.PD 7-139 38 6.4e-37 117.6 In-house 4-139 (141) Show / Hide
Range on Protein: 7-139
Range on HMM: 4-139/141
Sequence Identity: 38% (51 aa)

KIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDN-ANPL--REDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYI
.|.| ||||. .|... | |....| ..| . .|  |     ... || | . |   |.|. || | ||||  .| |. ..||||.||.||||.. ||.|
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl

MTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFY
  ..||  .. . ... .|   ||. |  || ||  
mkklalslndaydlvkkkksnisPnfnfmgqlldfe

Phosphatase nvec_DUSP15.AA DSPc 12-141 27 1.2e-35 125.88 Pfam 1-151 (151) Show / Hide
Range on Protein: 12-141
Range on HMM: 1-151/151
Sequence Identity: 27% (42 aa)

LYLGNIRDSK-DAEQLQEHNITHILSIHDNANPLRE----DIMYKCIH-AAD---------SPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRST
||||.  ... | ..||.|.|||...  .. .. ..    .. |..|    |         ...... ..|.....||..|| |  ..|||| |||||| 
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

TICAAYIMTITELSWRQTLQAI-----RANR-SIANPNYGFKRQLQDFYNK
..|.||.|    .| .  .  .     . .| .. .|| .|.|||......
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ

Phosphatase nvec_DUSP15.AA Subfamily.DSP10.PD 5-138 35 2.2e-34 109.6 In-house 2-138 (141) Show / Hide
Range on Protein: 5-138
Range on HMM: 2-138/141
Sequence Identity: 35% (49 aa)

MNKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHD---NANPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAA
. .|.| |.||| .|..| . |. ..|...| .     |    .....|| | . ||. |.|   |.| .|||.  | .. . |||| ||||||.|.  |
assilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvia

YIMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDF
|.|  ..|| ... . .. .| |  || .|  || .|
yvmkhlslslseaykfvkekrPiisPnlnfmGqllef

Phosphatase nvec_DUSP15.AA Subfamily.DSP14.PD 5-139 31 1.6e-31 100.4 In-house 2-136 (138) Show / Hide
Range on Protein: 5-139
Range on HMM: 2-136/138
Sequence Identity: 31% (43 aa)

MNKIIPGLYLGnIRDSKDAEQLQEHNITHILSIHDN-ANPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYI
...| . |||.  .  .. |.|....||.|. .  . ...  ||. .  |. .|.|...|...|.|  . |.. . |. ..||||.||.||| ... ||.
lseitesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlayl

MTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFY
|   .|| |.. ......|.| .|| || .||.|. 
mkyeklsLreayklvksaRpiirPnvGFwkqlidyE

Phosphatase nvec_DUSP15.AA Subfamily.LRR-DSP.PD 6-139 35 4.8e-31 98.6 In-house 3-135 (137) Show / Hide
Range on Protein: 6-139
Range on HMM: 3-135/137
Sequence Identity: 35% (48 aa)

NKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDnANPLREDI-MYKCIHAADSPDQDLMPFFQECIEFIHSCRVKeMNCLVHCIAGISRSTTICAAYIM
..||..||||    ....  |.. |.||||.. |  .||  |.  |  |.. | .. |.. .|.|   ||.. | |    |.|| ||.|||.|.  ||.|
dliidklylgcresamnksilkdnnvthilavad-fkplypdlfkyliidiedvdeadiyqhfkemnafidegrek-ggvlihcragvsrsatlviaylm

TITELSWRQTLQAIRANRSIANPNYGFKRQLQDFY
   .| ....|. .  .|.  .|| ||. ||. | 
kknslkfkealdlvikkrpriypnrgfldqlkkfe

Phosphatase nvec_DUSP15.AA Subfamily.DSP8.PD 5-141 33 5.1e-30 95.6 In-house 2-141 (143) Show / Hide
Range on Protein: 5-141
Range on HMM: 2-141/143
Sequence Identity: 33% (47 aa)

MNKIIPGLYLGNIRDSKDAEQLQEHNITHIL--SIHDNA-NPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAA
...|.| ||||  .|| | | |.. .|...|  | . ..   | ..  .  |   |. . .|.|.|....|||  .| .. ..|||| ||||||.|.  |
ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaia

YIMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFYNK
|||   |.|  .. . ..  |.  .||. |  || .....
yimktlemsldeayrfvkekrptispnlnflgqLleyeke

Phosphatase nvec_DUSP15.AA Subfamily.Slingshot.PD 6-138 34 2.4e-29 93.2 In-house 3-136 (139) Show / Hide
Range on Protein: 6-138
Range on HMM: 3-136/139
Sequence Identity: 34% (46 aa)

NKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDNA-NPLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIM
||   ||||   .. . |.|.|.....|| .  .  |   |.. |. |.  |....||.....|  .||. .. |. ..||||  |.|||...  || | 
skifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayam

TITELSWRQTLQAIRANRSIANPNYGFKRQLQDF
  |||  ..|. .. .|||..|| || .||. . 
keyelsleealeyvkerrsiikpnkgflkqlkvy

Phosphatase nvec_DUSP15.AA Subfamily.DSP3.PD 5-138 31 1.5e-28 90.7 In-house 2-145 (148) Show / Hide
Range on Protein: 5-138
Range on HMM: 2-145/148
Sequence Identity: 31% (46 aa)

MNKIIPGLYLGNIRDSKDAEQLQEHNITHILSIHDN---------ANPLRE-DIMYKCIHAADSPDQDLMPFFQECIEFIHSCR-VKEMNCLVHCIAGIS
.. . |..|.|.   .|| |.|..  |||.|   ..         |.  .. .| |  ... |.|. ||  .|.|  .||..    |.   |||| .|||
vdevypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGis

RSTTICAAYIMTITELSWRQTLQAIRANRSIAnPNYGFKRQLQDF
||.|.  ||.|   .|. .. ....| .|.|  || || .|| ..
RsatlvlayLmirrkltlkeaiktvrkkreil-PneGflkqLlel

Phosphatase nvec_DUSP15.AA Subfamily.STYX.PD 5-138 33 4.7e-25 79.4 In-house 2-143 (146) Show / Hide
Range on Protein: 5-138
Range on HMM: 2-143/146
Sequence Identity: 33% (47 aa)

MNKIIPGLYLGNIRDSK--DAEQLQEHNITHILSIHDNAN------PLREDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRST
|..|.|||.||    ..    |.|.|| ||||. | .| .       ......|  .  ||.. .... .. .  ||| ..  |  . |||||||||...
mqeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsa

TICAAYIMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDF
  ||||    | .|.. . .. .|   ||| || .||...  
alviayimetyglkyreafayvqerrfcinpnegfvsqlkey

Phosphatase nvec_DUSP15.AA Subfamily.STYXL1.PD 8-138 23 7.5e-19 59.6 In-house 5-140 (143) Show / Hide
Range on Protein: 8-138
Range on HMM: 5-140/143
Sequence Identity: 23% (32 aa)

IIPG-LYLGNIRDSKDAEQLQEHNITHILSIHDNANPLREDIMY--KC--IHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAY
..|| ||||| ..... .  ..  .   . .  .|..| . .    |   |.  |... ||.....| ..||.. . ..   ||    |||||... .||
vlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiay

IMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDF
.|   ... ..... ..  ..  .|| .|  ||...
lmyskkitlkkaykylkkckenvkPnrafveqlseW

Phosphatase nvec_DUSP15.AA Subfamily.PTPMT1.PD 57-140 28 1.2e-13 42.3 In-house 65-145 (146) Show / Hide
Range on Protein: 57-140
Range on HMM: 65-145/146
Sequence Identity: 28% (24 aa)

DSPDQDLMpffQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFYN
..|... .   .| .|||.. . |. .  ||| || .||.|. |.|.|. ..||  .  ..... |..   .    | || |..
eapslekl---eegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefke

Phosphatase nvec_DUSP15.AA Subfamily.R_Nematode_3.PD 69-124 28 1.5e-08 25.5 In-house 186-247 (267) Show / Hide
Range on Protein: 69-124
Range on HMM: 186-247/267
Sequence Identity: 28% (17 aa)

ECIEFIHSCRVKEMNCLVHCIAGISRSTTICA---AYIMTITEL---SWRQTLQAIRANRSI
| .| |. ..  . . .|||..||||| |. |   .| . |..    . .. ....|. |  
ealelikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRag

Phosphatase nvec_DUSP15.AA Subfamily.DSP23.PD 25-125 21 1.7e-08 25.8 In-house 8-110 (128) Show / Hide
Range on Protein: 25-125
Range on HMM: 8-110/128
Sequence Identity: 21% (22 aa)

QLQEHNITHILSIHDNANPLREDIMYKCIHAADSPDQDlMPFFQECIEFIHSC---RVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRAN
| .. | ...|. ....|  |      ... | ||    |  .   .... .     ||    |||. |. |. |. | |..   .|....  .| .|  
fladqGirvlvslttegapyseaapsltlrridipdfc-PPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkr

RSIA
.   
rkGs

Phosphatase nvec_DUSP15.AA Subfamily.N_Nematode_1.PD 52-104 33 1.1e-07 22.6 In-house 167-220 (265) Show / Hide
Range on Protein: 52-104
Range on HMM: 167-220/265
Sequence Identity: 33% (18 aa)

CIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICA-AYIM
..  | ||.   |     .|.... |...   .||| ||| |. || | .||. 
hyqWtdWPdrGvPpadlaalelleavrgskgPivvhCsaGiGrtGtivaieyil

Phosphatase nvec_DUSP15.AA Subfamily.PTPDC1.PD 78-123 26 4.5e-07 20.8 In-house 163-208 (229) Show / Hide
Range on Protein: 78-123
Range on HMM: 163-208/229
Sequence Identity: 26% (12 aa)

RVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRANRS
..| .  ||| ||  |   . |.|..  ..|.  . .. .|..|. 
aleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp

Phosphatase nvec_DUSP15.AA Subfamily.Laforin.PD 64-125 22 5.9e-07 20.5 In-house 87-148 (165) Show / Hide
Range on Protein: 64-125
Range on HMM: 87-148/165
Sequence Identity: 22% (14 aa)

MPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRANRSIA
.  . ... ..|.   |     ||| ||. |||.|   ... . . | ..    . |.| ..
venlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv

Phosphatase nvec_DUSP15.AA Subfamily.CDC14.PD 72-122 25 6.1e-07 20.6 In-house 189-239 (258) Show / Hide
Range on Protein: 72-122
Range on HMM: 189-239/258
Sequence Identity: 25% (13 aa)

EFIHSCRVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRANR
.|.. .   | .  ||| ||. | .|. ..|..   ...  .|.  .|  |
kfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriar

Phosphatase nvec_DUSP15.AA Subfamily.R_Nematode_2.PD 56-103 26 2.6e-06 18.1 In-house 168-216 (261) Show / Hide
Range on Protein: 56-103
Range on HMM: 168-216/261
Sequence Identity: 26% (13 aa)

ADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAA-YI
.. ||...    .|. | ..  .  |   .||| ||| |.... .. |.
eeWpdrgvPkshaelfeLlelvkksekPivvhCsaGiGRtmafigteyl

Phosphatase nvec_DUSP15.AA Subfamily.N12.PD 49-103 25 3.5e-06 17.5 In-house 163-221 (270) Show / Hide
Range on Protein: 49-103
Range on HMM: 163-221/270
Sequence Identity: 25% (15 aa)

MYKCIHAADSPDQDLMPFFQECIEFIHSCRV----KEMNCLVHCIAGISRSTTICAAYI
. . .|  . ||..     .. .|.|.. |     ...  .||| ||. |  ||.|  .
kvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidy

Phosphatase nvec_DUSP15.AA Subfamily.DSP11.PD 59-123 21 3.7e-06 18.0 In-house 58-123 (141) Show / Hide
Range on Protein: 59-123
Range on HMM: 58-123/141
Sequence Identity: 21% (14 aa)

PD-QDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRANRS
|. .|.  | ..  ||....  ...   |||  |. |.  .   |..  ...|  . ..|    | 
pekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearG

Sequence
Name Sequence Type Origin Length Description Download
nvec_DUSP15.AA Protein None 146 None Fasta, JSON
nvec_DUSP15.NA RNA None 438 None Fasta, JSON
nvec_DUSP15.AA.PD_4-141 Protein Phosphatase Domain None 138 None Fasta, JSON