• Phosphatome.Net

Gene nvec_PRL

nvec_PRL
Species: N.vectensis
Alias: nvec_PRL
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: PRL
Protein domain

Protein domains of nvec_PRL.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_PRL.AA Subfamily.PRL.PD 1-139 67 2.2e-72 232.9 In-house 1-139 (140) Show / Hide 
Range on Protein: 1-139
Range on HMM: 1-139/140
Sequence Identity: 67% (94 aa)

MKFLITDRPTNSTLPQYIQDLKKYDAHTVVRVCEPTYNTETLSKEGIIVLDWPFDDGAAPPKQLVEDWLKLLKGKFKERPGSCVAVHCVAGLGRAPVLVA
..|||.|.|...|....|. |||.....|||||||.|..|.| .||| |||..|||||.|||..|..||.||| ||||.|.|.|||||||||||||||||
lrflildepsdetvekfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlva

LALIESGMKYEDAVEFIRRKRRGAINAKQLSYLERYKPT
|||||.||||||||||||.|||||||.|||..||.||..
lalieaGmkyedavefirekrrgainskqlkflekykak
Phosphatase nvec_PRL.AA Family.DSP.PD 18-140 28 5.5e-22 70.1 In-house 125-247 (387) Show / Hide 
Range on Protein: 18-140
Range on HMM: 125-247/387
Sequence Identity: 28% (37 aa)

IQDLKKYDAHTVVRVCEPTYNT-EtlsKEGIIVLDWPFDDGAAPPKQLVedWLKLLKgkFKER---PGSCVAVHCVAGLGRAPVLVALALIES-GMKYED
. ||..    .|....   .  .   ..|| .|..|.||. ||| ...  . | ..  | |    ....|.||| ||.|| ..|..  |..| |...|.|
lewlkelgvtkivnltddkpqftk---elgikylripidDhnapplenl--fekaid--fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltlee

AVEFIRRKRRGAIN--AKQLSYLERYKPTK
....| ||.| |.   ..|..|...   | 
aldwvrskRpgvitpnqgflkqlkdlekek
Phosphatase nvec_PRL.AA Subfamily.CDC14.PD 16-135 25 7.8e-20 63.1 In-house 138-253 (258) Show / Hide 
Range on Protein: 16-135
Range on HMM: 138-253/258
Sequence Identity: 25% (31 aa)

QYIQDLKKYDAHTVVRVCEPTYNTETLSKEGIIVLDWPFDDGAAPPKQLVEDWLKLLKGKfkerpGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAV
....  .| . .|.||. .  |. .   ..|.  ||  | ||. |...... .|...           .|||| |||||  .|..  || .... .... 
klleyfrknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaeti

EFIRRKRRGAINAKQLSYLER
..|  | | . ..| .||.. 
awlriarPGsvigpqqtylve
Phosphatase nvec_PRL.AA Subfamily.PTPDC1.PD 36-130 29 1.5e-15 48.8 In-house 124-217 (229) Show / Hide 
Range on Protein: 36-130
Range on HMM: 124-217/229
Sequence Identity: 29% (29 aa)

TYNTETLSKEGIIVLDWPFDDGAAPPKQLVEDWLKLLKGKFKErpgSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAVEFIRRKRRGAINAK-QL
.|. | | ..||..  ....|  ... . . |  |...   .|   . .|||| |||||  ||.|  |.  . .. |.|....| ||  .|... |.
sYdpeelmrqgiyfynfglkDygvasleriLdivkvvdfalee---gkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqv
Phosphatase nvec_PRL.AA Subfamily.PTPMT1.PD 21-137 28 6.1e-12 37.1 In-house 20-144 (146) Show / Hide 
Range on Protein: 21-137
Range on HMM: 20-144/146
Sequence Identity: 28% (36 aa)

L-KKYDAHTVVRVCEPT------YNTETLSKEGIIVLDWPFDDGAA-PPKQLVEDWLKLLKGKFKErpGSCVAVHCVAGLGRAPVLVALALI-ESGMKYE
| .|.. ..|| ..|         .||  .|.|.  |  .  | .  | .. .|. ..... . ..  ||.| ||| || .|.  ||||. .  .. |.|
LvekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvask--gssvYvHCkAGrtRsatlvacylmkkkklspe

DAVEFIRRKRRGA-INAKQLSYLERYK
|.|...||.   .. ||.. |...|  
eavkflkkkRpqirlkskqwralqefk
Phosphatase nvec_PRL.AA Subfamily.DSP23.PD 53-129 28 7e-11 33.8 In-house 40-115 (128) Show / Hide 
Range on Protein: 53-129
Range on HMM: 40-115/128
Sequence Identity: 28% (22 aa)

PFDDGAAPPKQLVEDWLKLLKGKfkERPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAVEFIRRKRRGAINAKQ
.|   |  . |. ......    |. .  |.|||. ||||.  |.|  |..  |.  .||.  .|..|.|.|....  
dipdfcPPaleqvarlvriveea--ekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietve
Phosphatase nvec_PRL.AA Subfamily.PTEN.PD 22-121 31 1.2e-10 32.8 In-house 36-136 (305) Show / Hide 
Range on Protein: 22-121
Range on HMM: 36-136/305
Sequence Identity: 31% (31 aa)

KKYDAHTVVRVCEPTYNTETlSKEGIIVLDWPFDDGAAPPKQLVEDWLKLLKGKFKERPGSCVAVHCVAGLGRAPVLVALALIESGMKYE--DAVEFIRR
.|.... .|.     . |. |.    |   ||||  .|. .|.|.  . ..   ||     ||||| || ||. |...  |..||.| ..|...  .|| 
tvykgkgklrilnargeked-sdfdgrvavypfdDhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiyde

KR
  
kR
Phosphatase nvec_PRL.AA Subfamily.RNGTT.PD 36-129 30 3.5e-10 31.2 In-house 33-128 (140) Show / Hide 
Range on Protein: 36-129
Range on HMM: 33-128/140
Sequence Identity: 30% (28 aa)

TYNTETLSKEGIIVLDWPF-DDGAAPPKQLVEDWLKLLKGKFKERPGSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAVEFIRRKRRGAINAKQ
|. | |.|||.          | || |. .. ..|| |  .|..|.. ..|||  |  |.  |..  |.|   .. |.||.   . ||  ..    
yydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiyked
Phosphatase nvec_PRL.AA Subfamily.N13.PD 49-137 26 6.6e-08 23.9 In-house 162-252 (259) Show / Hide 
Range on Protein: 49-137
Range on HMM: 162-252/259
Sequence Identity: 26% (24 aa)

VLDWPFDDGAAPPKQLVEDWLKLLkgKFKErPGSCVAVHCVAGLGRAPVLVALA----LIE--SGMKYEDAVEFIRRKRRGAINAKQlSYLERYK
.||  .  . ...||.   ..   ....   . ..||| ||.||. ||...     |||    .. .. |. .|..|.| . .|.  |.||    
fvkwPdhgvPssaaelvqfvaevr--llqt-dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkd-qyifvyk
Phosphatase nvec_PRL.AA Subfamily.DSP1.PD 81-126 36 1.1e-07 23.5 In-house 79-124 (139) Show / Hide 
Range on Protein: 81-126
Range on HMM: 79-124/139
Sequence Identity: 36% (17 aa)

GSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAVEFIRRKRrGAIN
|  | ||| ||. |.  .| . |. |. ...|.| ||....|   |.
gGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrr-siis
Phosphatase nvec_PRL.AA Subfamily.DSP11.PD 56-126 25 2.2e-07 22.2 In-house 54-127 (141) Show / Hide 
Range on Protein: 56-126
Range on HMM: 54-127/141
Sequence Identity: 25% (18 aa)

DGAAPPKQLVEDWLKLLKGKF--KERPGSCVAVHCVAGLGRAPVLVALALIE-SGMKYEDAVEFIRRKRRGAIN
| |. |... . .|     ..  .. ..|||  |. |.  |.   ||.  |.. |||.|   . |  ...    
GhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhsle
Phosphatase nvec_PRL.AA Subfamily.DSP3.PD 80-130 29 2.5e-07 22.2 In-house 88-139 (148) Show / Hide 
Range on Protein: 80-130
Range on HMM: 88-139/148
Sequence Identity: 29% (15 aa)

PGSCVAVHCVAGLGRA-PVLVALALIESGMKYEDAVEFIRRKRRGAINAKQL
.. | ||||.|. |.  . .|  .|   .. ..|.. .|.||    |   | 
kngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkreilPneGfl
Phosphatase nvec_PRL.AA Subfamily.Slingshot.PD 79-124 34 4.4e-07 21.3 In-house 77-123 (139) Show / Hide 
Range on Protein: 79-124
Range on HMM: 77-123/139
Sequence Identity: 34% (16 aa)

RPGSCVAVHCVAGLGR-APVLVALALIESGMKYEDAVEFIRRKRRGA
. || | |||  |. | | ...| |. | ....|.|.|.....|. .
ekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerrsii
Phosphatase nvec_PRL.AA Subfamily.R_Nematode_3.PD 82-132 27 4.7e-07 20.9 In-house 199-257 (267) Show / Hide 
Range on Protein: 82-132
Range on HMM: 199-257/267
Sequence Identity: 27% (16 aa)

SCVAVHCVAGLGRAPVLVALAL-----IE--SGMKYEDAVEFIRRKRRGAINA-KQLSY
. | |||..| .|. .|.|  |     |.  . ... . .. .|..| |||.  ..|..
tpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelaf
Phosphatase nvec_PRL.AA Subfamily.N_Nematode_1.PD 47-110 33 5.3e-07 20.7 In-house 168-225 (265) Show / Hide 
Range on Protein: 47-110
Range on HMM: 168-225/265
Sequence Identity: 33% (21 aa)

IIVLDWPfDDGaAPPKQLVedWLKLLKGKFKERpgSCVAVHCVAGLGRAPVLVALALIESGMKY
.   ||| | | .|| .|    |.||.   ...  . ..||| ||.||.  .||...|   .  
yqWtdWP-drG-vPpadla--alelleavrgsk--gPivvhCsaGiGrtGtivaieyildklle
Phosphatase nvec_PRL.AA Subfamily.N12.PD 28-113 22 6.1e-07 20.3 In-house 148-231 (270) Show / Hide 
Range on Protein: 28-113
Range on HMM: 148-231/270
Sequence Identity: 22% (19 aa)

TVVRVCEPTYNTETLSKEGIIVLDWPFDDGAAPPKQLVEdWLKLLKgKFKERPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDA
..|  . . . |. . . .   .||  .  . .|.|.|  ..|.. ...|.  . ..||| || ||. ...|. .. . .| |   
flirtLkveaqkesrkvyqfhytaWPDhgvPssakslle-lielvr-elqesedaPlvvhCsaGvGrtGtiiaidyvrellkaeki
Phosphatase nvec_PRL.AA Subfamily.RB.PD 63-116 22 7.6e-07 20.3 In-house 174-228 (261) Show / Hide 
Range on Protein: 63-116
Range on HMM: 174-228/261
Sequence Identity: 22% (12 aa)

QLVEDWLKLLKGKFKER-PGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAVEF
. . |... .. . ...   . . ||| ||.||. . .||  .   .. .| |. 
ktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdv
Phosphatase nvec_PRL.AA Subfamily.DSP19.PD 81-124 31 1.1e-06 20.1 In-house 79-123 (139) Show / Hide 
Range on Protein: 81-124
Range on HMM: 79-123/139
Sequence Identity: 31% (14 aa)

GSCVAVHCVAGLGRAP-VLVALALIESGMKYEDAVEFIRRKRRGA
. .| ||| ||  |.. | .|  . .. ...|.|.| .| .|. .
dgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpci
Phosphatase nvec_PRL.AA Subfamily.DSP12.PD 82-126 26 1.4e-06 20.0 In-house 82-128 (143) Show / Hide 
Range on Protein: 82-126
Range on HMM: 82-128/143
Sequence Identity: 26% (12 aa)

SCVAVHCVAGLGRA-PVLVALALIESGMKYEDAVEFIRRKRRGA-IN
| ||| ||. |   . .|  . ..... |.|......|.. .  |  
gavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkkeiepN
Phosphatase nvec_PRL.AA Subfamily.DSP8.PD 81-133 30 2.9e-06 18.8 In-house 81-132 (143) Show / Hide 
Range on Protein: 81-133
Range on HMM: 81-132/143
Sequence Identity: 30% (16 aa)

GSCVAVHCVAGLGRAPV-LVALALIESGMKYEDAVEFIRRKRrGAINaKQLSYL
..| ||| ||  |..   .|  . .  |....| .|.. ||  .|. ..| .| 
ngkvlvhclaGisrsatvaiayimktlemsldeayrfvkekr-ptis-pnlnfl
Phosphatase nvec_PRL.AA Subfamily.DSP10.PD 79-122 34 3.8e-06 18.3 In-house 79-123 (141) Show / Hide 
Range on Protein: 79-122
Range on HMM: 79-123/141
Sequence Identity: 34% (15 aa)

RPGSCVAVHCVAGLGRA-PVLVALALIESGMKYEDAVEFIRRKRR
. || | ||| ||. |.  | .|  .   ..  ..| .|.. || 
krgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrP
Phosphatase nvec_PRL.AA Subfamily.N_Nematode_4.PD 55-118 31 4.7e-06 17.6 In-house 172-236 (264) Show / Hide 
Range on Protein: 55-118
Range on HMM: 172-236/264
Sequence Identity: 31% (21 aa)

DDGAAPPKQ-LVEDWLKLLKGKFKERPgscVAVHCVAGLGRAPVLVALALIESGMKYEDAVE---FIR
|  || .   | . .| .| | ||.|   . ||| ||.||.  || . . .  ..    .|    .| 
rdqvaPldaapviklykavkkkkkekP---ivvhcsaGvGrtatlvGidyatirirenseievldivr
Phosphatase nvec_PRL.AA Subfamily.DSP15.PD 82-124 34 4.7e-06 18.1 In-house 79-122 (138) Show / Hide 
Range on Protein: 82-124
Range on HMM: 79-122/138
Sequence Identity: 34% (15 aa)

SCVAVHCVAGLGRAPVLV-ALALIESGMKYEDAVEFIRRKRRGA
. | |||.||. |.  || |  .  . ...|||.. ..  |  |
gnvlvhclaGisrsvtlvvayimtvtelswedalkavkaarsva
Phosphatase nvec_PRL.AA Subfamily.R_Ecdysozoa.PD 80-117 44 6.2e-06 17.0 In-house 200-237 (269) Show / Hide 
Range on Protein: 80-117
Range on HMM: 200-237/269
Sequence Identity: 44% (16 aa)

PGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAVEFI
| . ||| || ||. ..|||.|.   .| || |. .  
srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdif
Phosphatase nvec_PRL.AA Subfamily.STYX.PD 81-128 34 6.7e-06 17.5 In-house 86-133 (146) Show / Hide 
Range on Protein: 81-128
Range on HMM: 86-133/146
Sequence Identity: 34% (17 aa)

GSCVAVHCVAGLGRAPVLVALALIES-GMKYEDAVEFIRRKRrGAINAK
|  | ||  ||. |.  ||   ..|. |.|| .|  .....|   ||..
ggkvlvhgnagisrsaalviayimetyglkyreafayvqerr-fcinpn
Phosphatase nvec_PRL.AA Subfamily.DSP6.PD 80-122 31 7e-06 17.3 In-house 80-123 (141) Show / Hide 
Range on Protein: 80-122
Range on HMM: 80-123/141
Sequence Identity: 31% (13 aa)

PGSCVAVHCVAGLGRA-PVLVALALIESGMKYEDAVEFIRRKRR
| | ||| ||. |.  | .|  . .  .  .|| .....|.   
kkskvlvhclaGvsrsvtvtlaylmkklalslndaydlvkkkks
Sequence
Name Sequence Type Origin Length Description Download
nvec_PRL.AA Protein None 154 None Fasta, JSON
nvec_PRL.NA RNA None 462 None Fasta, JSON
nvec_PRL.AA.PD_47-139 Protein Phosphatase Domain None 93 None Fasta, JSON