• Phosphatome.Net

Gene nvec_PTPMT1-A

nvec_PTPMT1-A
Species: N.vectensis
Alias: nvec_PTPMT1-A
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: PTPMT1
Protein domain

Protein domains of nvec_PTPMT1-A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_PTPMT1-A.AA Subfamily.N9.PD 40-147 21 7e-06 17.2 In-house 115-226 (275) Show / Hide 
Range on Protein: 40-147
Range on HMM: 115-226/275
Sequence Identity: 21% (24 aa)

WYDRIDSTVILGALPFKSLTQKLVEEENVRAVVTL----NEEFETKHFCNTSeeWSEWGVKQLRLATVDFGNAPS--LDNLSEGVKFIEEIRSKGDSVYV
| .  .|.   | |  ... ..  |. .|| ..      .|. .  ||  .|  | ..|| .   . .|. ..       ... .   .. . .|  . |
wpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqfls--wPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivv

HCKAGRGRSATLVA
|| || ||. |...
hcsaGiGrtGtfit
Phosphatase nvec_PTPMT1-A.AA Subfamily.PTPMT1.PD 43-173 63 1.9e-64 207.4 In-house 1-145 (146) Show / Hide 
Range on Protein: 43-173
Range on HMM: 1-145/146
Sequence Identity: 63% (92 aa)

RIDSTVILGALPFKSLTQKLVEEENVRAVVTLNEEFETKHFCNTSEEWSEWGVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRS
|||.|||||||||.|||..|||.|||.|||.||||.|.|...|..|||...||.||.||||||..||||..|.|||.|||...|||.||||||||||.||
ridetvilGalPfrsltkeLvekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRs

ATLVACYLM--------------KSKRPHIRLASQQWSAVQQFHD
|||||||||              |.|||.|||.|.||.|.|.|..
atlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefke
Phosphatase nvec_PTPMT1-A.AA Family.DSP.PD 44-155 35 1.2e-23 75.5 In-house 110-212 (387) Show / Hide 
Range on Protein: 44-155
Range on HMM: 110-212/387
Sequence Identity: 35% (41 aa)

IDSTVILGALPFKSLTQKLvEEENVRAVVTLNeefetkhfCNT----SeewsEWGVKQLRLATVDFgNAPSLDN-LSEGVKFIEEIRSKGDSVYVHCKAG
|   ..|| |   . ...| .| .| ..| |.        ..     .    | |.| ||..  |. |||.|.| . . ..|||| ....  |.||||||
ilphlylgsllaaknlewl-kelgvtkivnlt--------ddkpqftk----elgikylripidDh-napplenlfekaidfieegndskgvVlVHCkaG

RGRSATLVACYLMKSKR
.|||.||...|||||..
kgRsgtliiaYlmkseg
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP12.PD 43-166 26 5.5e-18 56.9 In-house 4-119 (143) Show / Hide 
Range on Protein: 43-166
Range on HMM: 4-119/143
Sequence Identity: 26% (33 aa)

RIDSTVILGALPFKSLtQKLVEEENVRAVVTLNEEFETKHFCNTSEEWsewgvkqLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRS
.|.  . || |.     ..| .| .. .|... .|  ...  .....        . .  .|  ... |..| | |.|||| ..|...|.|||.||  ||
eilpglylggleavqe-rellkelkithvlsvikeelpelqkekgvks-------kliqilDepeedlLshldeavrFieeglekegavlvHClagvSRS

ATLVACYLMKSKRPHIRLASQQWS
.|.|. ||||...  .. | .  .
vtiviAYlmkkeklslekAlklvk
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP19.PD 95-163 37 2e-15 48.4 In-house 46-114 (139) Show / Hide 
Range on Protein: 95-163
Range on HMM: 46-114/139
Sequence Identity: 37% (26 aa)

VKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKRPHIRLASQ
.. . .  .|  ..  |. |.| ..|||| |||.  |.|||.||. |||..|  ||||... ... | .
ftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekale
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP23.PD 65-155 30 2.4e-14 45.0 In-house 11-93 (128) Show / Hide 
Range on Protein: 65-155
Range on HMM: 11-93/128
Sequence Identity: 30% (28 aa)

EENVRAVVTLNEEFETKhfcntSEEWSEWGVKQLrlATVDFgNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKR
.. .| .|.| .| ...     ||   . .....     ||   |.|. ... |. .||   |...| |||  |.||. ||.||||.|...
dqGirvlvslttegapy-----seaapsltlrri--dipdf-cPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeg
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP10.PD 97-157 42 3.5e-14 44.4 In-house 50-110 (141) Show / Hide 
Range on Protein: 97-157
Range on HMM: 50-110/141
Sequence Identity: 42% (24 aa)

QLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKRPH
|.   | |.     ...| ..||||.|..| .| |||.||  ||||.|  |.|| ..    
ykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayvmkhlsls
Phosphatase nvec_PTPMT1-A.AA DSPc 114-155 45 4e-14 51.02 Pfam 71-112 (151) Show / Hide 
Range on Protein: 114-155
Range on HMM: 71-112/151
Sequence Identity: 45% (19 aa)

LSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKR
... ..||.  |.||  |.|||.||  |||.|...||||...
FPMATDFIDDCRQKGGKVLVHCQAGISRSACLCIAYLMKYRN
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP1.PD 106-158 42 2.1e-13 42.0 In-house 57-109 (139) Show / Hide 
Range on Protein: 106-158
Range on HMM: 57-109/139
Sequence Identity: 42% (22 aa)

GNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKRPHI
.|  .  ..| ..||.....||  |.|||.||  ||||.|  ||||.|. .. 
kkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrl
Phosphatase nvec_PTPMT1-A.AA Subfamily.CDC14.PD 63-155 33 3.4e-13 41.3 In-house 143-225 (258) Show / Hide 
Range on Protein: 63-155
Range on HMM: 143-225/258
Sequence Identity: 33% (30 aa)

VEEENVRAVVTLNEEfetkhfCNTSEEWSEWGVKQLRLATVDfGNAPSLDNLSEGVKFIEEIrsKGdSVYVHCKAGRGRSATLVACYLMKSKR
..||...| ||..          ... . |.. | |  .| |  ||   | . .. .|..  .| .. |||||| || .||..|||.||    
frknnvttivrLnkk------lYdakkftdaGfahlDlffiD-GtvPsdailkkfleiteka--eG-aiavhCkaGLGrtgtligcylikhyr
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP6.PD 94-155 36 1.2e-12 39.1 In-house 47-108 (141) Show / Hide 
Range on Protein: 94-155
Range on HMM: 47-108/141
Sequence Identity: 36% (22 aa)

GVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKR
.| ....  |  ..     . | ..||.| |||  .| ||| ||  || |.. .||||..  
elkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlaylmkkla
Phosphatase nvec_PTPMT1-A.AA Subfamily.PTPDC1.PD 79-155 32 3.1e-12 37.9 In-house 119-193 (229) Show / Hide 
Range on Protein: 79-155
Range on HMM: 119-193/229
Sequence Identity: 32% (25 aa)

ETKHFCNTSEEWSEWGVKQLRLATVDFGnAPSLDNLSEGVKFIEEIRsKGDSVYVHCKAGRGRSATLVACYLMKSKR
|.. |  . ||  . |.     .  |.| ..||... . || ..    .   . ||| ||.||   |.||||. .||
eesGfsYdpeelmrqgiyfynfglkDyg-vasleriLdivkvvdfal-eegkiavHCHAGlGRtGvliacylvyakr
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP8.PD 56-153 29 4.8e-12 37.5 In-house 16-106 (143) Show / Hide 
Range on Protein: 56-153
Range on HMM: 16-106/143
Sequence Identity: 29% (28 aa)

KSLTQKLVEEENVRAVVTLNEEfetkhfCNTSEEWSEwGVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKS
.|| ..|... ..  |. . |.      |. . |  .  .. ||.   |  .   |. . . ..||. .||.  .| ||| ||. ||||...|.||  
dsldeellkklgisyvlnises------cpkdvellk-esrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiayimkt
Phosphatase nvec_PTPMT1-A.AA Subfamily.STYXL1.PD 59-163 27 6.5e-12 37.3 In-house 20-118 (143) Show / Hide 
Range on Protein: 59-163
Range on HMM: 20-118/143
Sequence Identity: 27% (29 aa)

TQKLVEEENVRAVVTLNEEFETkhFCNTSEEwsewGVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKRPHI
... ..  |.|.| .  . |   . .. ..     .| |..|  |  .|  |..|.| |.|||. . .|. | |  . |  |||.....||| ||.   .
npaikkdlkvkahvnvssdaek--liaglad----vakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitl

RLASQ
 | . 
kkayk
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP14.PD 93-161 38 6.5e-12 37.2 In-house 43-111 (138) Show / Hide 
Range on Protein: 93-161
Range on HMM: 43-111/138
Sequence Identity: 38% (26 aa)

WGVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKRPHIRLA
.||.....  |  .|   . . | .. |||...||  . |||.||. |||.||  |||| ..  .| | 
edvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmkyeklsLrea
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP15.PD 98-152 37 1.2e-11 36.3 In-house 48-102 (138) Show / Hide 
Range on Protein: 98-152
Range on HMM: 48-102/138
Sequence Identity: 37% (20 aa)

LRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMK
|..   |  . .    ..| ..|| . | .| .|.||| ||  || |||. |.| 
lcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimt
Phosphatase nvec_PTPMT1-A.AA Subfamily.DSP3.PD 82-162 29 1.6e-11 35.8 In-house 42-123 (148) Show / Hide 
Range on Protein: 82-162
Range on HMM: 42-123/148
Sequence Identity: 29% (24 aa)

HFCNTSEEWSEWGVKQLRLATVDFGNAPSLDNLSEGVKFIEE-IRSKGDSVYVHCKAGRGRSATLVACYLMKSKRPHIRLAS
.   ..| ... ..| | .   |. ..      .| ..||.| ...|.  |.|||..|  ||||||  ||| ...  .. | 
kvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeai
Phosphatase nvec_PTPMT1-A.AA Subfamily.Laforin.PD 90-153 35 3.5e-11 34.6 In-house 66-129 (165) Show / Hide 
Range on Protein: 90-153
Range on HMM: 66-129/165
Sequence Identity: 35% (22 aa)

WSEWGVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKS
. | |.  . | | |.     ..|| ..| ..  .  ||  |||||.|| |||...|  .|.  
ykeeglayiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyv
Phosphatase nvec_PTPMT1-A.AA Subfamily.Slingshot.PD 82-156 33 3.6e-11 34.6 In-house 30-107 (139) Show / Hide 
Range on Protein: 82-156
Range on HMM: 30-107/139
Sequence Identity: 33% (26 aa)

HFCNTSEEWSEWGV---KQLRLATVDFGNAPSLDNLSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKSKRP
.  | ..|  ..     | |..   |  ..  |..  |  ||||....|| .| |||| |  |||. |  | ||. . 
yilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayamkeyel
Phosphatase nvec_PTPMT1-A.AA Subfamily.PTEN.PD 78-157 28 8.3e-11 33.2 In-house 42-123 (305) Show / Hide 
Range on Protein: 78-157
Range on HMM: 42-123/305
Sequence Identity: 28% (23 aa)

FETKHFCNTSE-EWSEWgVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSK--GDSVYVHCKAGRGRSATLVACYLMKSKRPH
. . ..  .| | |..  ...    .|  |.|.|. |.| |. ...  ..     | ||||||.||. .....||.||.  . 
gklrilnargekedsdf-dgrvavypfdDhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikk
Phosphatase nvec_PTPMT1-A.AA Subfamily.LRR-DSP.PD 113-157 50 8.8e-10 30.0 In-house 63-106 (137) Show / Hide 
Range on Protein: 113-157
Range on HMM: 63-106/137
Sequence Identity: 50% (22 aa)

NLSEGVKFIEEIRSKGdSVYVHCKAGRGRSATLVACYLMKSKRPH
. |   ||.| | ||  | .||.||  |||||| .|||| .. . 
hfkemnafidegrekg-gvlihcragvsrsatlviaylmkknslk
Phosphatase nvec_PTPMT1-A.AA Subfamily.RNGTT.PD 68-167 24 1.1e-08 26.4 In-house 21-118 (140) Show / Hide 
Range on Protein: 68-167
Range on HMM: 21-118/140
Sequence Identity: 24% (24 aa)

VRAVVTLNeefETKHFCNTsEEWSEWGVKQLRLATVDFGNAPSLDNLSEGVKFIEEIRSK--GDSVYVHCKAGRGRSATLVACYLMKSKRPHIRLASQQW
.. |. |    .|. . .  || .. |||. .|     |.||. .. .. .| ..|  .|  .. . |||  |  |   |...||.. ..  | . ..  
lglvidlt---ntsryydk-eelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalf

SA
  
ak
Phosphatase nvec_PTPMT1-A.AA Subfamily.R_Nematode_3.PD 73-149 32 1.1e-08 26.2 In-house 145-219 (267) Show / Hide 
Range on Protein: 73-149
Range on HMM: 145-219/267
Sequence Identity: 32% (24 aa)

TLNEEFETKHFCNTSEEWSEWGVKQLRLATVDFGNAPSLDnlSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACY
|.|..|..... | |.  |  |. | .      |||      | .. |. ...   .| |||..| .|||||.|   
elsedvekrtlvvtfekkkeftvthllykgWkelnapeep--kealelikfveksktpvvVHCsdGisRsatlaaie
Phosphatase nvec_PTPMT1-A.AA Subfamily.N_Nematode_1.PD 59-153 19 4e-08 24.3 In-house 144-221 (265) Show / Hide 
Range on Protein: 59-153
Range on HMM: 144-221/265
Sequence Identity: 19% (18 aa)

TQKLVEEENVRAVVTLNEEFETKHFcnTSEEWSEWGVKQLRLATVdfgnapsldnlsegvKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKS
... ... ...  .. ... ...|.    ..| . || .  ||..               ...|..|..   . ||| || ||.|.||  ..   
deevikvtvlevegaGektrkvthy--qWtdWPdrGvPpadlaal---------------elleavrgskgPivvhCsaGiGrtGtivaieyild
Phosphatase nvec_PTPMT1-A.AA Subfamily.TPIP.PD 102-154 34 1.8e-07 22.5 In-house 9-63 (245) Show / Hide 
Range on Protein: 102-154
Range on HMM: 9-63/245
Sequence Identity: 34% (19 aa)

TVDFGNAPSLDNLSEGVKFIEEIRSKGD--SVYVHCKAGRGRSATLVACYLMKSK
..|  | | |..|    | ..|  .|     | .||| |.||  |.| ..|..|.
middhnvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliase
Phosphatase nvec_PTPMT1-A.AA Subfamily.STYX.PD 118-153 45 5.4e-07 21.1 In-house 76-111 (146) Show / Hide 
Range on Protein: 118-153
Range on HMM: 76-111/146
Sequence Identity: 45% (16 aa)

VKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKS
.||..  .||  | || .||  |||.|| .|.|.. 
kefiddslqkggkvlvhgnagisrsaalviayimet
Phosphatase nvec_PTPMT1-A.AA DSPc 45-174 20 2e-06 13.27 SMART 1-172 (172) Show / Hide 
Range on Protein: 45-174
Range on HMM: 1-172/172
Sequence Identity: 20% (35 aa)

DSTVILGALPFKSLTQKL------VEEENVRAVVTLNEEFETKHFCNT-------SEEWSEWGVKQLRLATV---D-------FGNAPSLDNLSEGVKFI
. . |.. | . | .  .       .. |. .|. . .|.. ..|..        ..||.  . .....      |       .  .. .. ..| ..||
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECP-WNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFI

EEIRSKGDSVYVHCKAGRGRSATLVACYLM-------------------KSKR-PHIRLASQQWSAVQQFHDY
.. |.||  |.|||.||  |||||...|||                   |..| |.|.    .|   ... . 
HDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase nvec_PTPMT1-A.AA Subfamily.R_Nematode_2.PD 70-153 20 3.8e-06 17.8 In-house 149-218 (261) Show / Hide 
Range on Protein: 70-153
Range on HMM: 149-218/261
Sequence Identity: 20% (17 aa)

AVVTLNEEFETKHFCN-TSEEWSEWGVKQLRlatvdfgnapsldnlSEGVKFIEEIRSKGDSVYVHCKAGRGRSATLVACYLMKS
|.  . .|.|.       |||.. || . .                |  . .| ..   . . ||| || ||. ....   ... 
kvedstgkfatrtvthyqyeeWpdrgvPksh---------------aelfeLlelvkksekPivvhCsaGiGRtmafigteylar
Phosphatase nvec_PTPMT1-A.AA Subfamily.Tensin.PD 107-173 29 4.5e-06 17.7 In-house 14-82 (237) Show / Hide 
Range on Protein: 107-173
Range on HMM: 14-82/237
Sequence Identity: 29% (20 aa)

NAPSLDNLSEGVKFIEE-IRSKG-DSVYVHCKAGRGRSATLVACYLMKSKRPHIRLASQQWSAVQQFHD
||.|. |.  .| .|  . .   . | .||| |.|| .  ...|.  ||  .   |. .. |...| | 
laPpleklcsickalesWlkadpqnvvvlhckGgkGrigvvisaymhyskisasadaaldrfalkrfyd
Phosphatase nvec_PTPMT1-A.AA Subfamily.PRL.PD 88-152 34 4.8e-06 17.9 In-house 40-105 (140) Show / Hide 
Range on Protein: 88-152
Range on HMM: 40-105/140
Sequence Identity: 34% (23 aa)

EEWSEWGVKQLRLAtVDFGNAPSLDNLSEGVKFIEEI--RSKGDSVYVHCKAGRGRSATLVACYLMK
|.  | |.. | ||  | |..|. . . | .. ..|   .... .| ||| || ||.  |||  |. 
eklkeegievldla-fddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalalie
Sequence
Name Sequence Type Origin Length Description Download
nvec_PTPMT1-A.AA Protein None 180 None Fasta, JSON
nvec_PTPMT1-A.NA RNA None 540 None Fasta, JSON
nvec_PTPMT1-A.AA.PD_45-180 Protein Phosphatase Domain None 136 None Fasta, JSON