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Gene nvec_RNGTT

nvec_RNGTT
Species: N.vectensis
Alias: nvec_RNGTT
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: RNGTT
Protein domain

Protein domains of nvec_RNGTT.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_RNGTT.AA Subfamily.CDC14.PD 16-163 24 6.8e-12 35.9 In-house 110-244 (258) Show / Hide 
Range on Protein: 16-163
Range on HMM: 110-244/258
Sequence Identity: 24% (36 aa)

VIADRFFAFKTPLSSRYDDQIPeaNRFQLPMLCSYFQTLKVKvgLIIDLTNTnrFYDKNELERlTGIKHVKLQCRgHGETPSPDQTQLFINICcrywDKN
.| ..| |.  |  ..  ..    .  .   | .||. ..|.   |. | .    ||... .  .|..|. |     | .||.   . |..|.    .| 
iipnkfialagphnkskvedGy--tllaPeklleyfrknnvt--tivrLnkk--lYdakkftd-aGfahlDlffi-DGtvPsdailkkfleit----eka

PGElIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPPGIY
 |. | |||  |  ||| || .||. .   . . ..  .  .||  . 
eGa-iavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvi
Phosphatase nvec_RNGTT.AA Subfamily.RNGTT.PD 40-177 64 8e-71 226.6 In-house 3-139 (140) Show / Hide 
Range on Protein: 40-177
Range on HMM: 3-139/140
Sequence Identity: 64% (89 aa)

NRFQLPMLCSYFQTLKVKVGLIIDLTNTNRFYDKNELERLtGIKHVKLQCRGHGETPSPDQTQLFINICCRYWDKNPGELIGVHCTHGFNRTGFLIISYL
..|.  ||.||..|||||.||.||||||.|.|||.|||.  |.|..||||||.||.|...||.|||........|.|.|.||||||||||||||||..||
eafepemlksylktlkvklglvidltntsryydkeeleke-gvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL

VEKEDWSIEAAVECFTKCRPPGIYKQEYLNELSRRYGD
|||||||.||||..|.|.|||||||..||.||..||.|
vekedwsveaavalfakarppGiykedylkelfkryed
MRNA_cap_enzyme nvec_RNGTT.AA mRNA_cap_enzyme 272-367 38 1.7e-53 127.53 Pfam 1-112 (213) Show / Hide 
Range on Protein: 272-367
Range on HMM: 1-112/213
Sequence Identity: 38% (43 aa)

QPVSMDR-QNIRFLHEKDYRVSWKADGTRYMMLVVGE---GQ---VYLIDRDNAVFSAPQFRFPQRKN--P---REHIFDTLIDGEMVFDKEGD----KI
|||||.| .|. || ...|.|.||.||.||||. ..    |    .|.||||. ..  . .||| ..|  .   ..|  .|| ||||..|.  .    . 
QPVSMSRRENMKFLKQNYYYVCWKTDGMRYMMFITDHPEYGEFKGCYMIDRDMNYYHVENMRFPCKYNKWGESLDKHHHYTLLDGEMCIDTIPMQETQCQ

HPRYLAYDIIKF
 |||| ||....
QPRYLIYDCVAI
Phosphatase nvec_RNGTT.AA Subfamily.DSP11.PD 40-174 41 1.1e-36 116.0 In-house 4-138 (141) Show / Hide 
Range on Protein: 40-174
Range on HMM: 4-138/141
Sequence Identity: 41% (56 aa)

NRFQLPMLCSYFQTLKVKVGLIIDLTNTNRFYDKNELERlTGIKHVKLQCRGHgETPSPDQTQLFINICCRYWD--KNPGELIGVHCTHGFNRTGFLIIS
.||    | .  |  . |.||.||||||.|.|.|.||.  .|.|..||.| || |.|. .. . |..   .. .  |. ..|||||||||||||.||  |
erfapedlleklqeknkklGLvidltntdryykkkeltd-egvkykklncpGh-evpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCr

YLVEKEDWSIEAAVECFTKCRPPGIYKQEYLNELSRR
|...|..| | |.| | ..|   . ...||..| .. 
ylidvegyspedaieafeearGhslerenyledLkkl
Phosphatase nvec_RNGTT.AA Family.DSP.PD 54-174 25 2.5e-20 63.4 In-house 129-243 (387) Show / Hide 
Range on Protein: 54-174
Range on HMM: 129-243/387
Sequence Identity: 25% (31 aa)

LKVKVGLIIDLTntnrfYDKNELERLTGIKHVKLQCRGHgETPSPDQTqlFINICCrYWDK--NPGELIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAV
. .|  |..||     .||.. .   |||......  | ..|....   |....  . ..  .... . |||..| .|.| ||| ||...|...|.|.. 
kelgvtkivnlt-----ddkpqftkelgikylripidDh-napplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleeal

ECFTKCRP-PGIYKQEYLNELSRR
. ..||   . .|..| .|..   
dwvrskRpgvitpnqgflkqlkdl
Phosphatase nvec_RNGTT.AA Subfamily.DSP23.PD 94-163 32 3.2e-11 33.7 In-house 45-112 (128) Show / Hide 
Range on Protein: 94-163
Range on HMM: 45-112/128
Sequence Identity: 32% (22 aa)

ETPSPDQTQLFINICCRYWDKnpGELIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPPGIY
|...| . ...|.    .|  .| .||||  |. ||| |.  |||..|. . . |.    | |.  |   
cPPaleqvarlvriveeaekk--eeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsie
Phosphatase nvec_RNGTT.AA Subfamily.PTPMT1.PD 67-161 24 1.7e-10 31.3 In-house 38-130 (146) Show / Hide 
Range on Protein: 67-161
Range on HMM: 38-130/146
Sequence Identity: 24% (23 aa)

TNRFYDKNELERLTGIKHVKLQCRGHGETPSPDQTQLFINICCRYwdKNPGELIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPPG
.... .. |  . .|.....|    ..|.|| .. .  ...  ..  .. |. . |||  |  | . |...||..|. .| | ||. . |.||  
lkalansteewkklGveqlqlatvDfteapslekleegvefiekv--askgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqi
Phosphatase nvec_RNGTT.AA Subfamily.PRL.PD 67-162 25 4.8e-09 26.5 In-house 33-125 (140) Show / Hide 
Range on Protein: 67-162
Range on HMM: 33-125/140
Sequence Identity: 25% (23 aa)

TNRFYDKNELERlTGIKHVKLQCrGHGETPSPDQTQLFINICCRYWDKNPGELIGVHCTHGFNRTGFLIISYLVEKeDWSIEAAVECFTKCRPPGI
.  || ..|.. .||. . |.    | .|. .  . ..... . . ..|.. ..|||  |. |.  |.   |.|.   . | |||   . ||    
cepsydaeklke-egievldlaf-ddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyedavefirekrrgai
Phosphatase nvec_RNGTT.AA Subfamily.PTPDC1.PD 120-169 38 1.7e-08 24.5 In-house 169-218 (229) Show / Hide 
Range on Protein: 120-169
Range on HMM: 169-218/229
Sequence Identity: 38% (19 aa)

IGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPPGIYKQEYLN
|.|||  |  ||| || .||| ... . | |..   . ||  |. .| ..
iavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqve
Phosphatase nvec_RNGTT.AA Subfamily.DSP12.PD 100-160 25 2.5e-08 24.4 In-house 69-124 (143) Show / Hide 
Range on Protein: 100-160
Range on HMM: 69-124/143
Sequence Identity: 25% (15 aa)

QTQLFINICCrywdkNPGELIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPP
..  ||. .      . .. . |||. |  |   ..| ||. ||..|.| |..   . .. 
eavrFieegl-----ekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkke
Phosphatase nvec_RNGTT.AA Subfamily.PTEN.PD 103-158 21 6.1e-07 19.4 In-house 80-136 (305) Show / Hide 
Range on Protein: 103-158
Range on HMM: 80-136/305
Sequence Identity: 21% (12 aa)

LFINICCRYWDKNPGELIGVHCTHGFNRTGFLIISYLVEKEDWSIE-AAVECFTKCR
...   .. ...  . . |||  |  ||| .| .||...   . .  |...... | 
eivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR
Phosphatase nvec_RNGTT.AA Subfamily.DSP19.PD 119-160 36 3.5e-06 17.3 In-house 81-122 (139) Show / Hide 
Range on Protein: 119-160
Range on HMM: 81-122/139
Sequence Identity: 36% (15 aa)

LIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPP
. |||  |  |.  ..|.||...|. |.| |.|   . ||. 
rvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpc
MRNA_cap_enzyme nvec_RNGTT.AA mRNA_cap_enzyme 389-450 33 2.1e-29 69.63 Pfam 149-213 (213) Show / Hide 
Range on Protein: 389-450
Range on HMM: 149-213/213
Sequence Identity: 33% (22 aa)

GLLNKTQEPFSIRAKQFFPLEKTAWIL---EHWVPKLTHENDGLIFNPAEDPYLPGRQASVLKWK
........|||.| | ..... .. ..   .  .|.| ||.||||| ....||.|||  ...|||
HWYRYDMFPFSVRFKDMWDNWHSEKLVYYFHKFIPHLCHEIDGLIFQCWDTPYVPGRCQNLFKWK
MRNA_cap_C nvec_RNGTT.AA mRNA_cap_C 453-550 34 1.1e-40 145.86 Pfam 1-138 (138) Show / Hide 
Range on Protein: 453-550
Range on HMM: 1-138/138
Sequence Identity: 34% (47 aa)

TLNSVDFILKIATVK---QEGCL---PRSVGYL-MV-----------GGFDRPF-------AEI--------KVTKELKAYNNRVIECTW--DN---KE-
..|.|||.||. . .   ..| |   ....|||  .           ||...||       ...        |.|...| |||. .||||  ||   .  
EMNTVDFMLKMCFECIGGEDGMLDRFQQWRGYLDYMEMPNFQKGRWWGGYNCPFFCKMYVFNKMRIFDIEWEKWTNDEKPYNNKIVECTWLVDNKQKGRP

-WKFLRVREDKSHANAYTTAQGVCESIRNPVTKEWLLE
 |.|.|.| ||| .| . ||  ||.|| ..|||| |.|
EWVFMRFRTDKSNPNHINTARKVCYSIEDNVTKEYLFE
Sequence
Name Sequence Type Origin Length Description Download
nvec_RNGTT.AA Protein None 590 None Fasta, JSON
nvec_RNGTT.NA RNA None 1770 None Fasta, JSON
nvec_RNGTT.AA.PD_47-174 Protein Phosphatase Domain None 128 None Fasta, JSON