Gene nvec_STYX
nvec_STYX
Species: N.vectensis
Alias: nvec_STYX
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_STYX.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_STYX.AA | Family.DSP.PD | 19-201 | 30 | 1.7e-35 | 113.5 | In-house | 92-269 (387) | Show / Hide |
Range on Protein: 19-201 Range on HMM: 92-269/387 Sequence Identity: 30% (55 aa) NEDDIADWTYSKRREMQEIVPGIFLGPYSAAmkSKLEHLKSQGITHIVCIRQNiEANFVKpnfPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKG . | . . . ....|| |...||. .|| ..|| || |.|.|| . .. . .| | ... || . . |...... ..| .. |.......| dldtydhfervengkpseilphlylgsllaa--knlewlkelgvtkivnltdd-kpqftk---elgikylripidDhnapplenlfekaidfieegndsk GKVLVHGNAGISRSAALMIAYIMETYGLAYREAFLFVQQRRF-CINPNEGFTQQLMEYEPIYLANYQAKQQIANMESMGRPNGG .|||| .||..||. | |||.|. .|| . ||. .|...| .|.||.|| .||...| .| . . . ..|....| | gvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrfvissivqnlg |
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| Phosphatase | nvec_STYX.AA | Subfamily.STYX.PD | 33-178 | 80 | 1e-92 | 298.1 | In-house | 1-146 (146) | Show / Hide |
Range on Protein: 33-178 Range on HMM: 1-146/146 Sequence Identity: 80% (118 aa) EMQEIVPGIFLGPYSAAMKSKLEHLKSQGITHIVCIRQNIEANFVKPNFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRS |||||.||.||||||||||||||.||..|||||||||||||||..|||||..|.||||||||.|.||||||.|.||.|.||...|||||||||||||||| emqeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrs AALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYEPI |||.||||||||||.|||||..||.|||||||||||..||.|||.| aalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeai |
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| Phosphatase | nvec_STYX.AA | DSPc | 33-178 | 35 | 1e-58 | 202.3 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 33-178 Range on HMM: 1-172/172 Sequence Identity: 35% (61 aa) EMQEIVPGIFLGPYSAAMKSKLEHLKSQGITHIVCIRQNIEANFVKP------------NFPNDFLYLVLD-VAD-------TTTENIIRYFPQVKAFVD ...|| |...|| |...|..... || .|||... .....|| .. ... .|.|. . . | ....|| |||.|..|.. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH DCVSKGGKVLVHGNAGISRSAALMIAYIMETYGLAYREAFLFV-----QQRR-FCINPNEGFTQQLMEYEPI || .|||||||| |||||||.| |||.| .... |..|. || .||| ..|.||..|..||.|.| . DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | nvec_STYX.AA | DSPc | 41-178 | 38 | 2.3e-50 | 177.01 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 41-178 Range on HMM: 1-151/151 Sequence Identity: 38% (59 aa) IFLGPYSAAMKSKLEHLKSQGITHIV-CIRQNIEANFVKPNFPNDFLYL-VLD------VADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRS ..|| |...| .... |. ||||.. |.. . ...| ... ... . |.| ......|| |||....|.||| .|||||||| .|||||| LYLGSYPHHM-ADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRS AALMIAYIMETYGLAYREAFLFV-----QQRR-FCINPNEGFTQQLMEYEPI |.|.|||.| .... |.||. || .||| .|.|| .|. ||.||| . ACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP1.PD | 35-176 | 39 | 1.5e-40 | 128.9 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 35-176 Range on HMM: 3-137/139 Sequence Identity: 39% (55 aa) QEIVPGIFLGpySAAMKSKLEHLKSQGITHIVCIRQNIEAnfvkpNFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAA ||.. ..|| || |.|. ||...||... . .... |.. | | . | |.....| .| .. |.|.. .|||.|||| .|||||||.. veildfLyLG--saehasnlqlLkelkitallnvsaelpn-----vfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsat LMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..||.|.. . ..||| ||.||| .|.|| ||..||.|.| ivlayLmkekkvrleeafefvkqrrsiisPnfgfvgqLlefe |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP19.PD | 34-176 | 38 | 2.1e-39 | 125.0 | In-house | 2-137 (139) | Show / Hide |
Range on Protein: 34-176 Range on HMM: 2-137/139 Sequence Identity: 38% (54 aa) MQEIVPGIFLGPYSAAMKskLEHLKSQGITHIVCIRQNIEANfvkpnFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSA ..|. | ..|| ..|.. .| ||...||||. . ... ||.|| |. ... |. .....|.... |... ||.| |||||||.||||. vaevkprlylgsqdvaad--keilkklkitHilnvavgvpnv-----fpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsa ALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..|||.|.. | ...|. |.. | ||.|||||..|| ||| svviaylmkdeelslekalekvrearpcikPneGFikqLkeye |
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| Phosphatase | nvec_STYX.AA | Subfamily.LRR-DSP.PD | 35-176 | 38 | 3e-36 | 114.7 | In-house | 3-135 (137) | Show / Hide |
Range on Protein: 35-176 Range on HMM: 3-135/137 Sequence Identity: 38% (54 aa) QEIVPGIFLGPYSAAMKSKleHLKSQGITHIVCIrqnieANfVKPNFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGkVLVHGNAGISRSAA ..|.....|| .|| ||....|||... |. .|| .|. | ||..|. |. .| ..| .. ||.|. ||| ||.| ||.||||. dliidklylgcresamnks--ilkdnnvthilav-----ad-fkplypdlfkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsat LMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE |.|||.| | ..||. .|...| |.||.|| .|| .| lviaylmkknslkfkealdlvikkrpriypnrgfldqlkkfe |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP15.PD | 34-176 | 36 | 1.9e-34 | 109.0 | In-house | 2-136 (138) | Show / Hide |
Range on Protein: 34-176 Range on HMM: 2-136/138 Sequence Identity: 36% (52 aa) MQEIVPGIFLGPYSAAMksKLEHLKSQGITHIVCIRQNIeanfvKPNFPnDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSA |....||...| . | . |.|. . ||||..| .. || .. |. || . .||. .....| . |. | .||.|||||||||| .| mnkvlpGlyvGnfrdak--dkeqleenkithilsihdsa-----kplle-dikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsv ALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..|||| | ...|. |.. | . ||| || .||.|.| tlvvayimtvtelswedalkavkaarsvanPnvGfrrqlqefe |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP12.PD | 33-177 | 31 | 2.4e-34 | 108.9 | In-house | 1-140 (143) | Show / Hide |
Range on Protein: 33-177 Range on HMM: 1-140/143 Sequence Identity: 31% (45 aa) EMQEIVPGIFLGPYSAAMKskLEHLKSQGITHIVCIRQNIEANFVKPNFPNDflyLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRS |..|| ||..|| .|... |.||. |||.. . .. .. | . .. ......|. .|......... .|......|.|.|||| .||.||| evseilpglylggleavqe--rellkelkithvlsvikeelpelqkekgvks---kliqilDepeedlLshldeavrFieeglekegavlvHClagvSRS AALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYEP ....|||.| ...| ..|. .|.. . |.||||| .|| .| vtiviAYlmkkeklslekAlklvkekkkeiepNegFleQLklfek |
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| Phosphatase | nvec_STYX.AA | Subfamily.Slingshot.PD | 36-177 | 38 | 4e-33 | 104.6 | In-house | 4-138 (139) | Show / Hide |
Range on Protein: 36-177 Range on HMM: 4-138/139 Sequence Identity: 38% (54 aa) EIVPGIFLGPYSAAmkSKLEHLKSQGITHIVCIRQNIEaNFvkpnFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAAL .| ..|| | |.||.|| .|...|. . ..|. || ||..| || . | |.......... . |.. . .|| ||||| |.||||. kifdhlylGsewna--snleelkengveyilnvtkeid-nf----fpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsast MIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYEP .||| | .|.| . ||. .|..|| .|.||.||..|| .|| viayamkeyelsleealeyvkerrsiikpnkgflkqlkvyeg |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP8.PD | 35-176 | 36 | 1.4e-32 | 103.0 | In-house | 3-139 (143) | Show / Hide |
Range on Protein: 35-176 Range on HMM: 3-139/143 Sequence Identity: 36% (51 aa) QEIVPGIFLGPYSAAMKSKLehLKSQGITHIVCIRQNIEAnfvKPNFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAA ..|.| ..|| .....| || .||.... | .. .. .... .. .| . | |. .|... .|.. |.| ..|. |||||||||||||... trilpnlylGsqkdsldeel--lkklgisyvlnisescpk---dvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsat LMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ||||| | ... ||. ||...| |.|| | .||.||| vaiayimktlemsldeayrfvkekrptispnlnflgqLleye |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP6.PD | 36-176 | 32 | 1.1e-31 | 99.9 | In-house | 4-139 (141) | Show / Hide |
Range on Protein: 36-176 Range on HMM: 4-139/141 Sequence Identity: 32% (46 aa) EIVPGIFLGPYSAAmkSKLEHLKSQGITHIVCIRQNIEANFVKPnfpNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAAL ||.| ..|| .| |.|| || .| ... . .|.. | . ... |. . . |. ..|. ..||. .|.|.. || ||||| ||.||| .. eilpllylGsakda--snlevlkklkikyvlnvtsnlpnkfees---gelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtv MIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..||.|... |. .|. .|.... | || | .||...| tlaylmkklalslndaydlvkkkksnisPnfnfmgqlldfe |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP14.PD | 34-176 | 34 | 7.3e-31 | 97.5 | In-house | 2-136 (138) | Show / Hide |
Range on Protein: 34-176 Range on HMM: 2-136/138 Sequence Identity: 34% (49 aa) MQEIVPGIFLGPYSAAMKsklEHLKSQGITHIVCIRQnieaNFVKPNFpNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSA . || . ..|. ..| | |.||...||.|| . . . ..... .|. .. . |.|. .... ..| .| . ... .||||.|||||.||||.| lseitesLylsgaaalkk---eklkkkkitlivnvtt----elpetkl-edvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsA ALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..||.| |. |||. .|...| |.|| || .||..|| slvlaylmkyeklsLreayklvksaRpiirPnvGFwkqlidyE |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP3.PD | 34-176 | 35 | 1.5e-30 | 96.5 | In-house | 2-146 (148) | Show / Hide |
Range on Protein: 34-176 Range on HMM: 2-146/148 Sequence Identity: 35% (53 aa) MQEIVPGIFLGPYSAAMKSklEHLKSQGITHIVCIRQNIEANFV--KPNFPND--FLYLVLDVADTTTENIIRYFPQVKAFVDDCVSK-GGKVLVHGNAG ..|. |....| ..|.. |.|| ||||.. .. . | ...| .| || ..| |. . .. .|| . |.|. .|. .|||||| ..| vdevypkvyvgdeavakdk--ekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvG ISRSAALMIAYIMETYGLAYREAFLFVQQRRfCINPNEGFTQQLMEYE |||||.|..||.| . |. .|| |...| .| ||||| .||.|.. isRsatlvlayLmirrkltlkeaiktvrkkr-eilPneGflkqLleld |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP10.PD | 34-176 | 31 | 1.9e-30 | 96.0 | In-house | 2-139 (141) | Show / Hide |
Range on Protein: 34-176 Range on HMM: 2-139/141 Sequence Identity: 31% (45 aa) MQEIVPGIFLGPYSAAMKskLEHLKSQGITHIVCIRQNIEANFVKPnfpNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSA . .|.| ..|| | . . |. ||.... . ... ..| . ... | ..| |....|. ..| . .|... ..|..||||.|||||||. assilpflllGnekdaad--kdaldrlgikyvlnvttsvPnffeek---glvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsa ALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..|||.|. .|. .||. ||...| | || .| ||.|.| tvviayvmkhlslslseaykfvkekrPiisPnlnfmGqllefe |
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| Phosphatase | nvec_STYX.AA | Subfamily.STYXL1.PD | 36-176 | 26 | 3.2e-21 | 66.5 | In-house | 4-141 (143) | Show / Hide |
Range on Protein: 36-176 Range on HMM: 4-141/143 Sequence Identity: 26% (38 aa) EIVPG-IFLGPYSAAMKSKLE-HLKSQGITHIVCIRQNieanfVKPNFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSA |..|| ..|| |. |.. ... || .. .. .. . .. | ..| |. ... . .| |... . .| |||.| ||||||| evlPgklylGnykqaqnpaikkdlkvkahvnvssdaek-----liagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsa ALMIAYIMETYGLAYREAFLFVQQRRFCINPNEGFTQQLMEYE ..|||.| . .....|. .... . ..|| .| .|| |.| aviiaylmyskkitlkkaykylkkckenvkPnrafveqlseWe |
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| Phosphatase | nvec_STYX.AA | Subfamily.PTPMT1.PD | 50-175 | 25 | 8.7e-14 | 42.0 | In-house | 13-143 (146) | Show / Hide |
Range on Protein: 50-175 Range on HMM: 13-143/146 Sequence Identity: 25% (33 aa) MKSKLEHL-KSQGITHIVCIRQNIE----ANFVKPNFPNDFLYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAALMIAYIMETY ..|. ..| . . . .|.. .. | || .. . .| | . | | . . |... ||| .| || || .|||.|...|.|... frsltkeLvekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkk GLAYREAFLFVQQRRFCINPNEGFTQQLMEY |. || |....| | .. . | |. klspeeavkflkkkRpqirlkskqwralqef |
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| Phosphatase | nvec_STYX.AA | Subfamily.Laforin.PD | 86-159 | 28 | 1.7e-10 | 31.3 | In-house | 72-145 (165) | Show / Hide |
Range on Protein: 86-159 Range on HMM: 72-145/165 Sequence Identity: 28% (21 aa) LYLVLDVADTTTENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAALMIAYIMETYGLAYREAFLFVQQRR |. | . | .||. .. .|| .. . || .| || |||. ||.|.. ... | . . |. .| ayiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakr |
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| Phosphatase | nvec_STYX.AA | Subfamily.CDC14.PD | 51-156 | 19 | 4e-10 | 30.2 | In-house | 137-236 (258) | Show / Hide |
Range on Protein: 51-156 Range on HMM: 137-236/258 Sequence Identity: 19% (21 aa) KSKLEHLKSQGITHIVCIRQNI--EANFVKPNFPNDFLYLVlDvADTTTENIIRYFPQVkafVDDCvskGGKVLVHGNAGISRSAALMIAYIMETYGLAY .. ||. .....|.|| . ... . .| . | |. . | . ...|.. | .. .... |.. || ||. | ..|. .|.. .|... eklleyfrknnvttivrLnkklYdakkftdaGfahlDlffi-D-GtvPsdailkkflei---teka---eGaiavhCkaGLGrtgtligcylikhyrfta REAFLFVQ |. ... aetiawlr |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP11.PD | 97-164 | 20 | 5.8e-07 | 19.9 | In-house | 60-128 (141) | Show / Hide |
Range on Protein: 97-164 Range on HMM: 60-128/141 Sequence Identity: 20% (14 aa) TENIIRYFPQVKAFVDDCVSKGGKVLVHGNAGISRSAALMIAYIMETYGLAYREAF-LFVQQRRFCINP .|.. .. .|| |.... .. . || |. |. |. |.... |. .| | . | .... kedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhsler |
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| Phosphatase | nvec_STYX.AA | Subfamily.DSP23.PD | 53-159 | 23 | 3.1e-06 | 17.8 | In-house | 5-107 (128) | Show / Hide |
Range on Protein: 53-159 Range on HMM: 5-107/128 Sequence Identity: 23% (25 aa) KLEHLKSQGITHIVCIRQNIEAN-FVKPNFPNDFLyLVLDVADTTTENIIRYFpqvkAFVDDCVSKGGKVLVHGNAGISRSAALMIAYIMETYGLAYREA ....| ||| ..| . .. ... . |. . . | . | . |.. |.. |.. | || |. |. .|. |.... ||| .| avqfladqGirvlvslttegapyseaapsltlrri-dipdfcPPaleqvarlv----riveeaekkeeavgvhcalGlGrtGtllacylvkeeglaadda FLFVQQRR |..|| iaevrkrr |
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| Phosphatase | nvec_STYX.AA | Subfamily.PRL.PD | 49-163 | 22 | 7.1e-06 | 16.3 | In-house | 13-126 (140) | Show / Hide |
Range on Protein: 49-163 Range on HMM: 13-126/140 Sequence Identity: 22% (26 aa) AMKSKLEHLKSQGITHIVC-IRQNIEANFVKPNfPNDFLYLVLDVADTTTENIIRYFP-QVKA-FVDDcvsKGGKVLVHGNAGISRSAALMIAYIMEtYG .... .|.|| . ....| .. .|. .| . . | | .| . ...... . .|. | .. .. | || ||. |. |...| |. | tvekfieelkkenvkevvrvcepsydaeklkee-gievldlafddGavPpkevvdeWlellkekfkee---pkstvavhcvaGlGraPvlvalalie-aG LAYREAFLFVQQRR-FCIN ..| |....| .|| mkyedavefirekrrgain |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_STYX.AA | Protein | None | 218 | None | Fasta, JSON |
| nvec_STYX.NA | RNA | None | 654 | None | Fasta, JSON |
| nvec_STYX.AA.PD_33-178 | Protein Phosphatase Domain | None | 146 | None | Fasta, JSON |