• Phosphatome.Net

Gene nvec_TPIP

nvec_TPIP
Species: N.vectensis
Alias: nvec_TPIP
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: TPIP
Protein domain

Protein domains of nvec_TPIP.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_TPIP.AA Subfamily.PTEN.PD 228-535 28 1.1e-52 170.1 In-house 1-303 (305) Show / Hide 
Range on Protein: 228-535
Range on HMM: 1-303/305
Sequence Identity: 28% (91 aa)

DLTYVTERVIAMSFPSSGKHKMYRNPISEVARFLDTKHSDHYKVYNLCSERSYDPSIFHNQVERILIDDHNVPRLSQLLYFCHNVREWLDKDPSNVIAVH
|..|.   .|..|.|    .|.... . .. ..|.|.. ...|...|....... | |...|  . .|||| |.|. |  ....| .||..||||.||||
disyilvnlivlsypvetyekllyrnslddlillltvykgkgklrilnargekedsdfdgrvavypfdDhnpptleLleeivedvdkwLkedksnVvavH

CKGGKGRTGTAICAWLIASGQFEQAQHSLEYFGVRRTDYSvgktyQGVQTPSQGRYVGYLEQIFTKLNrrMPPAVTLKLKTIKIDGIGGVGNGDGKDLRL
| ||||||. |||.|. ||....|. .|....  || ..     .||  ||| ||| | ... .         |.|..  |..| |    .  .      
CkaGkGRtGvmicayLlksgikksadealaiydekRtkdk-----kGVtiPSQrRYvqYfsklvkssv--pyskvslnvceirfsesscvqnlgmvecsi

EviinssvVCHMSCSEGQ-PG---QYFEDLDKLVIAVGETDCPsLTGDIKIKFYSNNPnvpvgyDHCAFYFWFHTSFIENYR------------LFLRRE
  | | |..|   |        |..| .. . .   | ..||.|...  ..|      |.   .||. ||. ||               | . |.|. ||
s-------vlhdsatenakpdrlktlpidfqksfvltikpsip-vsgdvkfeltkksp------dkiichfwlntffvrnyspcesdgtvnkyihtlsks

ELDNPHKPKVWKVYKETFAVDITF
    | . | | . | |       
eiddvhkdsehkrfseefkisivf
Phosphatase nvec_TPIP.AA Subfamily.TPIP.PD 285-536 51 3e-94 306.0 In-house 1-244 (245) Show / Hide 
Range on Protein: 285-536
Range on HMM: 1-244/245
Sequence Identity: 51% (127 aa)

FHNQVERILIDDHNVPRLSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICAWLIASGQFEQAQHSLEYFGVRRTDYSVGKTYQGVQTPSQGRYV
|||.|.||.|||||||.|..|..|...|.|||.||..||.|.|||||||||||..||.||||..|..|..||.||| ||||.......|||.|||| |||
fhnrvsrimiddhnvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaeesldyfgerrtdkthsnkfqGvetPsqnryv

GYLEQIFTKLNRRMPPAVTLKLKTIKIDGIggvgNGDGKDLRLEVIINSSVVChMSCSEGQPGqYFEDLDKLVIAVGETDCPSLTGDIKIKFYSNnpNVP
|||.|.    |  .||   | .| . |  |     ||  ||...|...  ||   |.| |.    . |..   | .   | | ||.|..|.|.  |.|  
gylaqvkhlynwnlpprrilfikrfiiysi----rgdvcdlkvqvvmekkvvf-sstslgncs-ilhdietdkilinvydgpplyddvkvqffss--nlp

VGYDHCAFYFWFHTSFIENYRLFLRREELDNPHKPKVWKVYKETFAVDITFH
|| | |.||| ||||.| || | |.||||||| |.||.|   |||.| |   
kyydncpfffwfntsfiqnnrlclprneldnphkqkawkiyppefaveilfg
Phosphatase nvec_TPIP.AA Family.DSP.PD 248-536 24 8.7e-49 157.6 In-house 113-378 (387) Show / Hide 
Range on Protein: 248-536
Range on HMM: 113-378/387
Sequence Identity: 24% (72 aa)

KMYRNPISEVARFLDTKHSDHYKVYNLCsersYDPSIFHN----QVERILIDDHNVPRLSQLlyFCHNVReWLDK--DPSNVIAVHCKGGKGRTGTAICA
..|  . . .  .   |.  . |. ||.    .|.. |..    .. || |||||.| |..|  |.  .. ....  |...|..||||.||||.|||.|.
hlylgsllaaknlewlkelgvtkivnlt----ddkpqftkelgikylripidDhnapplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliia

WLIASGQFEQAqHSLEYFGVRRtdysvgktyQGVQTPSQGrYVGYLEQIFTKLNRrmPPAVTLKLKTIKIDGIGGVGNGDGKDLRLEVIINSSVVchmsC
|. | ...    .|...  .|         .|| ||.|| .. .|..   ..    .   .. |....  ... .|. ..    | .   ....      
Ylmksegltle-ealdwvrskR---------pgvitpnqg-flkqlkdlekeklk--vssevmelrfvissivqnlgsvevsvsvlkkvatekak----l

SEGQpGQYFEDLDKLVIAVgeTDCPSLTGDIKIKFYSNNPnvPVGYDHCAFYFWFHTSFIENYRLFLRREELDNPHKPKVWKVYKETFAVDITFH
...     .. .|.|| .   | . | ||.|..... |.  .  .... . ..|.|..|.. .| | ..|||..|| |...|||. .|| | .  
drlk-iLvideqekvviti--kdglplsgDVkvelfkknl--dkiirdiilntfFvtnyikdeslvlvkkeldelhkskifdvykdseaveisee
Phosphatase nvec_TPIP.AA Subfamily.Tensin.PD 285-521 28 3e-27 86.3 In-house 1-224 (237) Show / Hide 
Range on Protein: 285-521
Range on HMM: 1-224/237
Sequence Identity: 28% (65 aa)

FHNQVERILIDDHNVPRLSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICAWLIASGQFEQAQHSLEYFGVRRTdysVGKTYQGVQTPSQGRYV
....|  .   |.  | | .|   |...  ||. || ||...||||||||.|  |.|..  |   . |...|. | ..|    . .  .||. ||| |||
lnekvldlGWPdllaPpleklcsickalesWlkadpqnvvvlhckGgkGrigvvisaymhyskisasadaaldrfalkrf---yddkvsgvtqPsqrryv

GYLEQIFTKLNrRMPpAVTLKLKTIKIDGIGGVGNGDGKDLRLEVIINSSVVChMSCSEGQPGqyfEDLDKLVIAVGEtdCPSLTGDIKIKFYSNNPNVP
 |......    ..  .  | |. . ..||    .. |    | .    ..|   |     .|   || ..|.|...  | ||. .| |  .   ..   
eyfsgllsgsi-kln-ssplflhyvilhgipnfdskggcrpflkiyqalqlvy-tsgvynvag---edterlcitiep--alllkgdvlvkcyhkklrst

VgyDHCAFYFWFHTSFIENYRLFLRREELDNPHKPKV
.  |   |||. |....| . .|.||. .| .     
t--rdvvfrvqfhtgaikdlklvfekedldealkder
Phosphatase nvec_TPIP.AA PTEN_C2 399-537 28 7e-25 91.17 Pfam 1-141 (141) Show / Hide 
Range on Protein: 399-537
Range on HMM: 1-141/141
Sequence Identity: 28% (43 aa)

PPAVTLKLKTIKI-DGIGGVGNGDGK-DLRLEVIINSSVVCHMSCSEGQPGQY----FEDLDKL-VIAVGETDCP-SLT--GDIKIKFYSNN-PNVPVGY
|| ..|.|. | .  ||  .. |.|  .. .... |  .|            |    .....|      . .. |  ..  ||.||..|... .. |  |
PPPKPLFLHCIIMDHGIPNFKQGGGCWRPYIQIYQNDQKVF-----------YTCKKYWHCKKYKQQKCCIFKFPQPCPVQGDVKIQCYHKGPSDLPWMY

DHCAFYFWFHTSFIE--NYRLFLRREELDNPHKPKVWKVYKETFAVDITFHQ
. | |.|||.|.|||  |.|| . ..|||...|.| || ... |.|.. |  
EECMFRFWFNTCFIEHNNNRLTFPKNELDKAWKDKKWKRFPPDFKVEVVFSE
Phosphatase nvec_TPIP.AA Subfamily.DSP11.PD 277-363 29 5.3e-12 36.5 In-house 32-122 (141) Show / Hide 
Range on Protein: 277-363
Range on HMM: 32-122/141
Sequence Identity: 29% (26 aa)

ERSYDPSIFHNQ---VERILIDDHNVPRLSQLLYFCHNVREWLD--KDPSNVIAVHCKGGKGRTGTAICAWLIASGQFEqAQHSLEYFGVRR
.| |... ....    ... .  |.||   ..  |...|.|.|.  ||  ..|.|||  |  |||  || .||    .. .....| ||   
dryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegys-pedaieafeear
Phosphatase nvec_TPIP.AA Subfamily.RNGTT.PD 297-363 33 1.1e-10 32.2 In-house 55-120 (140) Show / Hide 
Range on Protein: 297-363
Range on HMM: 55-120/140
Sequence Identity: 33% (22 aa)

HNVPRLSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICAWLIASGQFEqAQHSLEYFGVRR
. |   |   | . |.|.|.| |..||.|||  |  |||  |.|.|.   ...  . ... |   | 
GeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedws-veaavalfakar
Phosphatase nvec_TPIP.AA Subfamily.DSP23.PD 287-352 31 1.2e-09 29.1 In-house 34-97 (128) Show / Hide 
Range on Protein: 287-352
Range on HMM: 34-97/128
Sequence Identity: 31% (20 aa)

NQVERILIDDHNVPRLSQLLYFCHNVREWLDKDpsNVIAVHCKGGKGRTGTAICAWLIASGQFEQA
..|| |.|.  | | |.  . . | |  .|.  . ..|||  | ||||| .  .|... ..  .  
ltlrridipdfcPPaleqvarlvriveeaekke--eavgvhcalGlGrtGtllacylvkeeglaad
Phosphatase nvec_TPIP.AA Subfamily.PTPDC1.PD 278-352 29 2.5e-09 27.7 In-house 123-197 (229) Show / Hide 
Range on Protein: 278-352
Range on HMM: 123-197/229
Sequence Identity: 29% (23 aa)

RSYDPSIFHNQ---VERILIDDHNVPRLSQLLYFCHNVREWLdkdPSNVIAVHCKGGKGRTGTAICAWLIASGQFEQA
||||  . .|   .  . ..|..|. | ..|     |   |       |||||  |.||||  |...|. . ... . 
fsYdpeelmrqgiyfynfglkDygvasleriLdivkvvdfal---eegkiavHCHAGlGRtGvliacylvyakrltae
Phosphatase nvec_TPIP.AA Subfamily.RB.PD 264-341 33 3.9e-09 27.1 In-house 135-213 (261) Show / Hide 
Range on Protein: 264-341
Range on HMM: 135-213/261
Sequence Identity: 33% (26 aa)

KHSDHYKVYNLCSERSYDpSIFHNQVERILIDDHNVPRLSQ-LLYFCHNVREWLDKD-PSNVIAVHCKGGKGRTGTAICA
|. |.. . ..  |.  . .   .|.. .   ||.||. .. || |...|||...|.  .. | |||  | ||||| |  
keldewvirefkiekgke-krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfial
Phosphatase nvec_TPIP.AA Subfamily.CDC14.PD 321-364 41 2.9e-08 24.5 In-house 198-240 (258) Show / Hide 
Range on Protein: 321-364
Range on HMM: 198-240/258
Sequence Identity: 41% (18 aa)

SNVIAVHCKGGKGRTGTAICAWLIASGQFEqAQHSLEYFGVRRT
.  |||||| | ||||| | ..||   .|. |. .. .. . | 
eGaiavhCkaGLGrtgtligcylikhyrft-aaetiawlriarP
Phosphatase nvec_TPIP.AA Subfamily.N12.PD 288-349 33 1.1e-07 22.1 In-house 166-226 (270) Show / Hide 
Range on Protein: 288-349
Range on HMM: 166-226/270
Sequence Identity: 33% (21 aa)

QVERILIDDHNVPR-LSQLLYFCHNVREWLDKDpSNVIAVHCKGGKGRTGTaICAWLIASGQF
| .     ||.||.  ..|| . ..|||  ... .. ..|||  | ||||| |.|  ..  ..
qfhytaWPDhgvPssaksllelielvrelqese-daPlvvhCsaGvGrtGt-iiaidyvrell
Phosphatase nvec_TPIP.AA Subfamily.N13.PD 288-344 29 2.7e-07 21.1 In-house 159-214 (259) Show / Hide 
Range on Protein: 288-344
Range on HMM: 159-214/259
Sequence Identity: 29% (17 aa)

QVERILIDDHNVPRLS-QLLYFCHNVREWLDkdPSNVIAVHCKGGKGRTGTAICAWLI
... .   ||.||. . .|. |  .||.  .   .  |.|||  | ||.|. |.   .
hlnfvkwPdhgvPssaaelvqfvaevrllqt--dagPivvhcsaGiGrsGvlitidvv
Phosphatase nvec_TPIP.AA Subfamily.PRL.PD 261-348 24 4.4e-07 20.6 In-house 18-108 (140) Show / Hide 
Range on Protein: 261-348
Range on HMM: 18-108/140
Sequence Identity: 24% (22 aa)

LDTKHSDHYKVYNLCSERSYDPSIFHN---QVERILIDDHNVPRLSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICAWLIASGQ
... . .. |    . | ||| . ...   .|  .  || .||  . .  . . ..|   ..|....||||  | ||.   ..  || .| 
ieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalalieaGm
Phosphatase nvec_TPIP.AA Subfamily.R_Anemone_2.PD 291-340 35 7e-07 19.8 In-house 163-213 (262) Show / Hide 
Range on Protein: 291-340
Range on HMM: 163-213/262
Sequence Identity: 35% (16 aa)

RILIDDHNVPR-LSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAIC
|..||   ..|| .  .|...  .   ..|.||| .| ||||. |      
ytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfia
Phosphatase nvec_TPIP.AA Subfamily.N_Choan_1.PD 288-340 35 7.9e-07 19.5 In-house 159-212 (262) Show / Hide 
Range on Protein: 288-340
Range on HMM: 159-212/262
Sequence Identity: 35% (19 aa)

QVERILIDDHNVPRL-SQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAIC
|.. .   || ||   ..|| | ..|..  .|.    . .||  | ||||| | 
qlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyia
Phosphatase nvec_TPIP.AA Subfamily.PTPMT1.PD 321-353 29 8.1e-07 19.8 In-house 86-120 (146) Show / Hide 
Range on Protein: 321-353
Range on HMM: 86-120/146
Sequence Identity: 29% (10 aa)

SNVIAVHCKGGKGRTGTAICAWLIASGQF--EQAQ
. . |||| |..| .| . ..|. . ..  |.|. 
gssvYvHCkAGrtRsatlvacylmkkkklspeeav
Phosphatase nvec_TPIP.AA Subfamily.N5_RR.PD 239-351 23 2.1e-06 18.1 In-house 112-226 (265) Show / Hide 
Range on Protein: 239-351
Range on HMM: 112-226/265
Sequence Identity: 23% (27 aa)

MSFPSSGKHKMYRNPISEVARFLDTKHSDHYKVYNLCSERSYD--PSIFHNQVERilIDDHNVPR-LSQLLYFCHNVREWLDKDPSN--VIAVHCKGGKG
. || . . ..  . .    .. .... ..|.| .|  . . .   |. |         ||..|.  ..|| ....|.|  ...  .   .|||  | ||
vyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytd--WPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiG

RTGTAIcAWLIASGQFEQ
||  | | .||  |... 
rtGcfi-aisiavrqlre
Phosphatase nvec_TPIP.AA Subfamily.R_Sponge_2.PD 265-341 27 2.1e-06 18.2 In-house 135-214 (262) Show / Hide 
Range on Protein: 265-341
Range on HMM: 135-214/262
Sequence Identity: 27% (22 aa)

HSDHYKV--YNLCSERSYDPSIFHNQVERILIDDHNVPRL-SQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICA
.. .|..  ..|..|.| . .   .| . .   .|.||.  ..|| . ..|..   |. ...| |.|. | ||||| |. 
kladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfial
Phosphatase nvec_TPIP.AA Subfamily.RK.PD 271-340 23 3.5e-06 17.2 In-house 146-218 (267) Show / Hide 
Range on Protein: 271-340
Range on HMM: 146-218/267
Sequence Identity: 23% (17 aa)

VYNLCS-ERSYDPSIFHNQVERILIDDH-NVPRLS-QLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAIC
.....   |...     .|.. .   .. .||     || . ..| .. ...    | |||  | ||.|| | 
ifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfia
Phosphatase nvec_TPIP.AA Subfamily.N3.PD 291-340 38 3.9e-06 17.0 In-house 163-212 (261) Show / Hide 
Range on Protein: 291-340
Range on HMM: 163-212/261
Sequence Identity: 38% (19 aa)

RILIDDHNVPRLS-QLLYFCHNVREWLDKDPSNVIaVHCKGGKGRTGTAIC
.   ||.||  | ..| | ..||.    . . |. ||| .| ||||  |  
ylaWpdhgvPddsadflefvervrklrsgkeePvv-vhCsaGigrtGvlil
Phosphatase nvec_TPIP.AA Subfamily.N_Fungi_PTP1.PD 265-343 29 4e-06 16.8 In-house 209-282 (343) Show / Hide 
Range on Protein: 265-343
Range on HMM: 209-282/343
Sequence Identity: 29% (22 aa)

HSDHYKVYNLCSERSYDPSIFHNQVERILIDDhnvprLSQLLYFCHNVREWLDKDPSNVIAVHCKGGKGRTGTAICAWL
|. |.||.|  .   | |.. |  . . . .       . |    . ...||.. |. | |||  | ||||| .     
vsepyevyqlqvknWkDlslllnPesilqale-----vkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDs
Sequence
Name Sequence Type Origin Length Description Download
nvec_TPIP.AA Protein None 538 None Fasta, JSON
nvec_TPIP.NA RNA None 1071 None Fasta, JSON
nvec_TPIP.AA.PD_285-388 Protein Phosphatase Domain None 104 None Fasta, JSON