• Phosphatome.Net

Gene Nvec_241000

Nvec_241000
Species: N.vectensis
Alias: Nvec_241000
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Myotubularin
Subfamily: MTMR1
Protein domain

Protein domains of Nvec_241000.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
GRAM Nvec_241000.AA GRAM 29-100 26 1.2e-10 41.16 Pfam 1-78 (78) Show / Hide 
Range on Protein: 29-100
Range on HMM: 1-78/78
Sequence Identity: 26% (21 aa)

AELSANQGELALCKGEKPQATAKDVTYLCPFTG-----PVRGFLYITNYKLFFKA-DDDIPF--TVEVPLGTIYRVEKIG
 .. .. ..  | ..||  .... ||| |.. .     || |..||||. . |.. . . ..  .. .|...| ||||..
EKFRKHFKD-PLPPNEKLIMDCN-VTYSCCLWRPFTKIPVQGRMYITNHHVCFYSDKFGWETYYKMVIPWNDITRVEKMQ
Myotub-related Nvec_241000.AA Myotub-related 195-311 55 1.2e-63 222.56 Pfam 1-121 (121) Show / Hide 
Range on Protein: 195-311
Range on HMM: 1-121/121
Sequence Identity: 55% (67 aa)

YELSDTYPAVVGVPSSVSDEDIKKVAVFRSRNRLPVLCWLHPTNNASITRASQPNRGLL-ARNKDDEKYFQAILEANP---QCHKLLIFDARPRINAVAN
||...|||| . ||.|.||...|||| |||..|.|||||.|. | |.|.|.|||  |.. .|.|.|||. |||..||.   |..|..|.||||..||.||
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANADMIQSRKMYIVDARPYTNAMAN

QAKGGGYETEENYQNTEVIFL
.||||||| ||.|.| |..|.
RAKGGGYENEEHYPNWEFVFM
GRAM Nvec_241000.AA GRAM 32-100 26 3.6e-10 41.04 SMART 1-80 (80) Show / Hide 
Range on Protein: 32-100
Range on HMM: 1-80/80
Sequence Identity: 26% (21 aa)

SANQGELALCKGEKPQAT-AKDVTYLCPFTG----PVRGFLYITNYKLFFKA-DDDIPF-----TVEVPLGTIYRVEKIG
.  . .  | ..||  .. .|.||| |.. .    || |..||.|... |.. . . .      .| .|...| |.||..
EKFRQHFKLPPNEKLINDCKKEVTYSCYLWRTYDIPVQGHMYISNNHICFCSNMFGWMTCPQYYKVVIPWADITRIEKMT
Phosphatase Nvec_241000.AA Subfamily.MTMR1.PD 325-473 79 2.3e-92 296.0 In-house 1-149 (149) Show / Hide 
Range on Protein: 325-473
Range on HMM: 1-149/149
Sequence Identity: 79% (119 aa)

KLKDICFPNIDDTHWLTNLENTKWLDHIKMIMAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRY
|||.|..|.||...||..||.||||.|||.|.||||||||.|....||||||||||||||.|||.|||||.|.||||| |||||||||||||||||..|.
klkeivypsideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaeri

GHGDKNHADDQRSPVFLQFIDCVWQVTRQFPCAFEFNETFLITILDHLY
|||||||||..||||||||||||||||||||.||||||.||||||||||
ghgdknhadadrspvflqfidcvwqvtrqfptafefneeflitildhly
Phosphatase Nvec_241000.AA Family.Myotubularin.PD 334-473 69 6.3e-75 239.0 In-house 2-141 (141) Show / Hide 
Range on Protein: 334-473
Range on HMM: 2-141/141
Sequence Identity: 69% (97 aa)

IDDTHWLTNLENTKWLDHIKMIMAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRYGHGDKNHAD
.....||..||.||||.|||.....||.|...|.. .|||.||||||||||.|||.||.||.||||||| |||||||||||||||||..|.|||||....
aeekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdksese

DQRSPVFLQFIDCVWQVTRQFPCAFEFNETFLITILDHLY
..||||||||||||.|.|.|||.||||||.|||.||||||
eersPvflqfidcvyqltkqfptafefnesflikildhly
Phosphatase Nvec_241000.AA Subfamily.MTMR3.PD 339-473 56 4.2e-61 194.3 In-house 1-135 (135) Show / Hide 
Range on Protein: 339-473
Range on HMM: 1-135/135
Sequence Identity: 56% (76 aa)

WLTNLENTKWLDHIKMIMAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRYGHGDKNHADDQRSP
.|..||.||||.|. ...  ||....|||.    |.||||||||||||..||| ||.||||||. ||.||.|.|||.||||| .| |||....  ..|.|
flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp

VFLQFIDCVWQVTRQFPCAFEFNETFLITILDHLY
||||..|||.|...|||..|||||.||. ...| |
vflqwldcvhqlkkqfptsfefneaflvklvqhty
Phosphatase Nvec_241000.AA Subfamily.C2-MTMR1.PD 335-471 55 1.4e-60 192.8 In-house 2-135 (137) Show / Hide 
Range on Protein: 335-471
Range on HMM: 2-135/137
Sequence Identity: 55% (75 aa)

DDTHWLTNLENTKWLDHIKMIMAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRYGHGDknhADD
| .||..||.|.|| .|| .. .|  ||  |..   | .|||||||||| ||..|| ||.||||||| |. ||||||||.|||||..|.|. |   .  .
sdvqwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggad---svs

QRSPVFLQFIDCVWQVTRQFPCAFEFNETFLITILDH
|||.||||.||..|||.|||.|||..  .|. . |. 
erspiflqfldclyqvtkqfpsafeytarlllklady
Phosphatase Nvec_241000.AA Subfamily.R_Nematode_3.PD 356-411 30 8.7e-08 21.0 In-house 184-228 (267) Show / Hide 
Range on Protein: 356-411
Range on HMM: 184-228/267
Sequence Identity: 30% (16 aa)

MAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTAlamllmdpyyrTIIGFEVLIEK
|. ....|  ..|.||||||||  |.  | |           ...|.. .|..   
pkealelikfveksktpvvVHCsdGisRsatlaa-----------ielgyqliiks
Phosphatase Nvec_241000.AA PTPc_motif 339-473 14 7.1e-07 27.37 SMART 1-92 (92) Show / Hide 
Range on Protein: 339-473
Range on HMM: 1-92/92
Sequence Identity: 14% (20 aa)

WLTNLENTKWLDH-----IKMIMAGAVRIADAVDRCRTSVVVHCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRYGHGDKNHAD
 .. .  | | ||      .    . ... ..|     ..|||||.|..|| .. |. |....                                     
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK---PIVVHCSAGCGRTGTFCAIDMMMQQ-------------------------------------

DQRSPVFLQFIDCVWQVTRQFPCAFEFNETFLITILDHLY
       . . ..|...  | | ... .| ..  .  .|.
-------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE
Sequence
Name Sequence Type Origin Length Description Download
Nvec_241000.AA Protein None 610 None Fasta, JSON
Nvec_241000.NA RNA None 1830 None Fasta, JSON
Nvec_241000.AA.PD_339-473 Protein Phosphatase Domain None 135 None Fasta, JSON