Gene Nvec_20426
Nvec_20426
Species: N.vectensis
Alias: Nvec_20426
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Nvec_20426.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Myotub-related | Nvec_20426.AA | Myotub-related | 180-340 | 44 | 1.4e-61 | 215.69 | Pfam | 1-121 (121) | Show / Hide |
Range on Protein: 180-340
Range on HMM: 1-121/121
Sequence Identity: 44% (72 aa)
FEVCRTYPRLHVIPSSISDSDLAKVASFRCSGRFPSIVWRHMTNGAVIARCSQPQVGWLGWRSAEDELLLQAIGQACTSDRYPSVAKLLNGITVNGINKK
.|.|.|||.. |.|.||||..| |||.|| |||| ..||| |||||.|||||.|||.|||..||| |.||| .|. |
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANA-D--------------------
HDMGDVLNGPADMSEDGPIARNPKQVLIVDARSYTAAYANRGKGGGFEYTEYYPNCEVMFM
. ......|||||.||.|.||| ||||.| .|.|||.|. ||
-------------------MIQSRKMYIVDARPYTNAMANRAKGGGYENEEHYPNWEFVFM
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| Phosphatase | Nvec_20426.AA | Subfamily.MTMR1.PD | 357-501 | 51 | 1.9e-57 | 184.0 | In-house | 4-149 (149) | Show / Hide |
Range on Protein: 357-501 Range on HMM: 4-149/149 Sequence Identity: 51% (75 aa) ALCSGSYDVPNWWSLIEKTNWLHHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAELLLDPFYRTIEGFKILIDREWLQFGHRFADRCGHG .. | | .| | .|.|.||.|| .... || |...|.. ||||||||||||.|. .|| ||||..||||.||..||..||| |||.||.| ||| eivypsideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighg SD-IDENERCPVFLQWLDCVHQLQKQFPSSFEFSETYLIKLLHHTY . ...| |||||..||| |...|||..|||.|..|| .| | | dknhadadrspvflqfidcvwqvtrqfptafefneeflitildhly |
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| Phosphatase | Nvec_20426.AA | Subfamily.MTMR3.PD | 368-501 | 71 | 6.7e-80 | 256.4 | In-house | 1-135 (135) | Show / Hide |
Range on Protein: 368-501 Range on HMM: 1-135/135 Sequence Identity: 71% (97 aa) WWSLIEKTNWLHHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAELLLDPFYRTIEGFKILIDREWLQFGHRFADRCGHGSDIDE-NERCP ..| .|||.||.|.|.|.|.||..|.||...||||.||||||||||.||||||.|||||.|||.||||.|..||||.|||.||||||||.|.|. ||||| flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp VFLQWLDCVHQLQKQFPSSFEFSETYLIKLLHHTY ||||||||||||.||||.||||.|..|.||..||| vflqwldcvhqlkkqfptsfefneaflvklvqhty |
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| Phosphatase | Nvec_20426.AA | Family.Myotubularin.PD | 366-501 | 60 | 5.1e-68 | 217.9 | In-house | 5-141 (141) | Show / Hide |
Range on Protein: 366-501 Range on HMM: 5-141/141 Sequence Identity: 60% (82 aa) PNWWSLIEKTNWLHHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAELLLDPFYRTIEGFKILIDREWLQFGHRFADRCGHGSDI-DENER .|.| .|.|.||.||..|.|.||.||..|......|.||||||||||.|...||.|||||.|||||||..||..|||.|||.||.|.|||.. .|.||. kkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdkseseeer CPVFLQWLDCVHQLQKQFPSSFEFSETYLIKLLHHTY |||||..|||.||.||||..|||.|..|||.|.|.| sPvflqfidcvyqltkqfptafefnesflikildhly |
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| Phosphatase | Nvec_20426.AA | Subfamily.C2-MTMR1.PD | 367-499 | 49 | 1.6e-52 | 168.0 | In-house | 5-135 (137) | Show / Hide |
Range on Protein: 367-499 Range on HMM: 5-135/137 Sequence Identity: 49% (66 aa) NWWSLIEKTNWLHHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAELLLDPFYRTIEGFKILIDREWLQFGHRFADRCGHGSDIdeNERCP .|.| .|.|.|| .|. ..|.| .| |. . .||||||||||.|.|.||.|||||.||||.|...||..||| |||.| .| |. . . || | qwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggadsv--sersp VFLQWLDCVHQLQKQFPSSFEFSETYLIKLLHH .|||.|||..|..|||||.||.. .|.|| . iflqfldclyqvtkqfpsafeytarlllklady |
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| Phosphatase | Nvec_20426.AA | PTPc_motif | 370-501 | 15 | 5.2e-08 | 33.87 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 370-501
Range on HMM: 1-92/92
Sequence Identity: 15% (22 aa)
SL--IEKTNWLHH-----ISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAELLLDPFYRTIEGFKILIDREWLQFGHRFADRCGHGSDIDEN
.. ||| .| .| ......|. |.|||||.|..|| ...|. .. .
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK---PIVVHCSAGCGRTGTFCAIDMMMQQ-------------------------------------
ERCPVFLQWLDCVHQLQKQFPSSFEFSETYLIKLLHHTY
. ...|... || | ... | |. . .
------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE
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| Phosphatase | Nvec_20426.AA | Subfamily.N_Nematode_1.PD | 386-421 | 44 | 4.8e-07 | 19.8 | In-house | 183-218 (265) | Show / Hide |
Range on Protein: 386-421 Range on HMM: 183-218/265 Sequence Identity: 44% (15 aa) KSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAE .|. ...||... |.||||| | || |||.. laalelleavrgskgPivvhCsaGiGrtGtivaiey |
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| Phosphatase | Nvec_20426.AA | Subfamily.N_Nematode_6.PD | 375-424 | 38 | 2.4e-06 | 17.7 | In-house | 160-209 (253) | Show / Hide |
Range on Protein: 375-424 Range on HMM: 160-209/253 Sequence Identity: 38% (19 aa) TNWL-HHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIvALAELLL || | . ..||. .. .|. | .|.||||| | || . || . .| anWPdhGvPdsflsalrllsvvkkdkkPivvhCsaGvGrtGtl-aliliil |
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| Phosphatase | Nvec_20426.AA | Subfamily.N14.PD | 376-425 | 30 | 5.2e-06 | 16.3 | In-house | 184-232 (275) | Show / Hide |
Range on Protein: 376-425 Range on HMM: 184-232/275 Sequence Identity: 30% (15 aa) NWLHHISMLIKSAVTIVHAVHTDGRPVVVHCSDGWDRTTqIVALAELLLD ..|... . . . . |..|. ||.||||.| || .. |..||. sfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtG-vlilsdllia |
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| Phosphatase | Nvec_20426.AA | Subfamily.R_Nematode_3.PD | 385-418 | 42 | 8.7e-06 | 15.8 | In-house | 184-217 (267) | Show / Hide |
Range on Protein: 385-418 Range on HMM: 184-217/267 Sequence Identity: 42% (14 aa) IKSAVTIVHAVHTDGRPVVVHCSDGWDRTTQIVA |.|. ....|.. ||||||||| |. ..| pkealelikfveksktpvvVHCsdGisRsatlaa |
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| Phosphatase | Nvec_20426.AA | Subfamily.N13.PD | 389-422 | 35 | 9.4e-06 | 15.8 | In-house | 181-214 (259) | Show / Hide |
Range on Protein: 389-422 Range on HMM: 181-214/259 Sequence Identity: 35% (12 aa) VTIVHAVHTDGRPVVVHCSDGWDRTTQIVALAEL |. |. ..|| |.||||| | |. .... . vaevrllqtdagPivvhcsaGiGrsGvlitidvv |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Nvec_20426.AA | Protein | None | 551 | None | Fasta, JSON |
| Nvec_20426.NA | RNA | None | 1653 | None | Fasta, JSON |
| Nvec_20426.AA.PD_370-501 | Protein Phosphatase Domain | None | 132 | None | Fasta, JSON |