Gene Nvec_109357
Nvec_109357
Species: N.vectensis
Alias: Nvec_109357
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Nvec_109357.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| UDENN | Nvec_109357.AA | uDENN | 1-86 | 28 | 2.1e-23 | 85.02 | SMART | 1-114 (114) | Show / Hide |
Range on Protein: 1-86 Range on HMM: 1-114/114 Sequence Identity: 28% (32 aa) MSRLADYFAIVGIDKDTSYG-----------------------EGLKGKVLQRFPPQDRKDVAFPEGIELFCQPTGWKT-----SYYCRPQTFFVSVLTD ..||.|||...|..||.... . |...|...|. |..| ||..|..||.| ||.. . ....||. |||| PHRLFDYFCVCGCPKDPGWWPDMHYACYQWEAPGRTGCFCPLQRSYKPEILYQYPEKDWWDFPFPDMIPMFCFPMGWDWCTWPRKTDRPDPQFFTFVLTD MEGDHKYLACFTFY ..| | .| .|| EDGSRRYGFCRRFY |
|||||||||
| DENN | Nvec_109357.AA | DENN | 131-282 | 29 | 1.5e-47 | 165.12 | Pfam | 1-172 (207) | Show / Hide |
Range on Protein: 131-282 Range on HMM: 1-172/207 Sequence Identity: 29% (50 aa) YVPKTLCLVSAVTYFEIL-KNCLTTIYLAFVAGN-------------EELLEKLVGSILGLVRVPPPGGPKLAFS---IGAGDRQTLCPPL-CDTI-PV- ..|| .|..| .|. . ...|. || . . . . ..|... ... | .||||.. || .|........ |. ... || WIPKCYCIISRWPWFNTFWRKWLDCIYRRYTSCPHPRIPPSSPRVGMWNPIERYIQNLCYEVPFPPPGRTQVLFSFIPLGVYEPILFQRPSPDSELHPVW TGVSVSTVFHQIGIHNMLSLFCAAVTENKILFISSSFVQLTTVTRAMLALMYPLKFSYVYIPILPAALLDFL ....... |.. |. |.|.|||...||..|.|.||.. ||.. .| .||.||.. ...||||.||.|||.| EHIDFHPLFRCLGPENCLHLFCCVLTEHRIIFHSSHYAMLTLCCHAVVALLYPFQWQHIYIPICPARLLDYL |
|||||||||
| UDENN | Nvec_109357.AA | uDENN | 1-86 | 37 | 8.4e-21 | 76.78 | Pfam | 1-95 (95) | Show / Hide |
Range on Protein: 1-86 Range on HMM: 1-95/95 Sequence Identity: 37% (37 aa) MSRLADYFAIVGIDK------DTSYGEGLKGKVLQRFPP----QDRKDVAFPEGIELFCQPTGWKTSYYC---RPQTFFVSVLTDMEGDHKYLACFTFY | ||.|||...| || ..|| |.|.|...|| |...| ||.....||.| ||. . ....||. ||||..| | .| ||| MQRLFDYFVVCGYDKDHMHPLGRSY----KPKILDQYPPKDHMQMFWDPPFPDAVPMFCFPDGWDWVTWRDRHYDPQFFSFVLTDEDGSRWYGFCRTFY |
|||||||||
| DENN | Nvec_109357.AA | DENN | 131-286 | 22 | 1.2e-34 | 122.29 | SMART | 1-204 (204) | Show / Hide |
Range on Protein: 131-286 Range on HMM: 1-204/204 Sequence Identity: 22% (46 aa) YVPKTL-CLVSAVTYFEILKNCLTTIYLAFV--AGNEELLE-KLVGSILGLVRVPPPGGPKLA------FSIG-AGDRQ---TLCPPLCDTIPVTG--VS ..|| . |..| .|.. ...| ..| . ... ... . .. | .||||.... |... .|... ..| |. . .|... .. WTPKCIHCIISHHPWFNWFRKWLNELYRYWQSDHNQHLFHHEFMIYLCHYPVPLPPPGKSIVFMSIVSYFQFHPPGNYYQPIEFCRPDDNRLPHIDENWD VSTVFHQIGIHNMLSLFCAAVTENKILFISSSFVQLTTVTRAMLALMYPLKFSYVYIPILPAALLDFL-------------------------------- ....|...|. |...|||....|..|.|.||.. |... .| .||.||.. . .||||||| .||.| LHELFECLGVENIMQLFCCILLERRIIFHSSNYQMLSMCCHAFVALLYPFQWQHIYIPILPASMLDYLCAPMPYIMGCHSSYFEEVKPEPDEEDDVVVVD IDAS || IDTN |
|||||||||
| DDENN | Nvec_109357.AA | dDENN | 346-415 | 34 | 3.9e-21 | 77.44 | SMART | 1-84 (84) | Show / Hide |
Range on Protein: 346-415 Range on HMM: 1-84/84 Sequence Identity: 34% (29 aa) QDKEIR-AIFLRIL--AQTFAG--YRSCLT--------LIRIHPKPVITFHKARFLEQRGMIG-DDFFSKVLESMSFSQFVATR ....|| |.||| . .|.| . ||..|. .|.||.|.|||.|. ||..| .|.....|.. ||||. | LNDQIREACFLRFFNYVQLFGHVDYRNYLRHHMIQQAYTWRKHPEPHITFNKESFLKSRPSHHMRPFLKMFCETQMFSQFIEER |
|||||||||
| SBF2 | Nvec_109357.AA | SBF2 | 528-755 | 46 | 6.30000000001e-108 | 362.56 | Pfam | 32-233 (233) | Show / Hide |
Range on Protein: 528-755 Range on HMM: 32-233/233 Sequence Identity: 46% (109 aa) RKLEVLKDCVSYIFDNKISEARKALPSVLRSLKSKGAQLALCHELSLRAKQNRS-VLEHDQFDLVVRLMNNALQEDASMDNTAVAAALLPLTSTFCRKLA |.||||. |.||||||||.||.| .| |||.||.. | ..||.||.|.. |||. ||.|.|||.|||.|| |||.. ||| .||||||||...|||||. RRLEVLRNCISYIFDNKILEAKKMFPAVLRALKGRAARICLCRELNLHCQQNRHFVLDHQQFDMVVRMMNCALQDCCSMDEYGVAAALLPLSTAFCRKLC TGCMQFAYTCVQDHPIWEKQQFWEEAFYTDVQTQIKQLYIVEEAPRAVAEDTLEKPDRSSRSSLTPSAKHRSFTGKENMLSKESRDSSDSETYFQIK--- .| .|||||||||||.| ||||| .||.|||..|. || . .. ...... . .. . |. PGVHQFAYTCVQDHPVWKNQQFWEACFYQDVQNHIRELYL--------------------------------NMHHDEQKTWSDWCHKQEPCAMEIAAEQ --KWATMKQEERDNLISSEESIVYSQAIHYANRM .|.|| | |...||| |||||||||||| MRLWPTMDKEKQQELVQKEESTVYSQAIHYANRM |
|||||||||
| DDENN | Nvec_109357.AA | dDENN | 346-415 | 35 | 8.2e-20 | 72.7 | Pfam | 1-77 (77) | Show / Hide |
Range on Protein: 346-415 Range on HMM: 1-77/77 Sequence Identity: 35% (27 aa) QDKEIRAIFLRILAQTFAGYRSCLTLIRIHPKP----VITFHKARFLEQ-RGMIGDDFFSKVLES--MSFSQFVATR ....|..||| .||.|..||..|. ||.||.| ..||.|. ||.. | .| ....|. . |.||. | HNQQVREAFLRFFAQLFGHYRNFLRYIRQHPRPWTDQMYTFQKEAFLKSRRPKSHRPFLKQFMETQVQMFAQFIQER |
|||||||||
| GRAM | Nvec_109357.AA | GRAM | 871-959 | 18 | 2.2e-12 | 47.31 | Pfam | 1-78 (78) | Show / Hide |
Range on Protein: 871-959 Range on HMM: 1-78/78 Sequence Identity: 18% (17 aa) RKIKIMRPALLPGEEMLCNG----LRCYLVPDGRELGRGGEVGGPTLLPAEGAAFLTNYRVIFKGTPVDQFASEMIVTRSFPVGSVVREKKIN .|.. . ..||..| | . .|.| .. |..|. |. ..||..|.|.. ... . ... .| ....| .|. EKFRKHFKDPLPPNEKLIMDCNVTYSCCLWRPF------------TKIPVQGRMYITNHHVCFYSDKFGWET---YYKMVIPWNDITRVEKMQ |
|||||||||
| Myotub-related | Nvec_109357.AA | Myotub-related | 1159-1216 | 42 | 3.3e-20 | 78.25 | Pfam | 1-64 (121) | Show / Hide |
Range on Protein: 1159-1216 Range on HMM: 1-64/121 Sequence Identity: 42% (27 aa) YTVCRSYPAVVVVPQSISDDTVLRVAKNHRQNRFPVAIWKHPKNKATLVRAG----GI--ERSS |..|..||| .|||.|||||.. .||| ...|||| .| |..|.|...|.. |. |.. YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCK |
|||||||||
| GRAM | Nvec_109357.AA | GRAM | 873-959 | 17 | 5.2e-14 | 53.78 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 873-959 Range on HMM: 1-80/80 Sequence Identity: 17% (16 aa) IKIMRPALLPGEEMLCNG------LRCYLVPDGRELGRGGEVGGPTLLPAEGAAFLTNYRVIFKGTPVDQFASEMIVTRSFPVGSVVREKKIN .|. .. || .| |.| .||| .. .|. | ...|....|.. . ...... .....| ....| .|. EKFRQHFKLPPNEKLINDCKKEVTYSCYLWRTY-------------DIPVQGHMYISNNHICFCSNMFGWMTCPQYYKVVIPWADITRIEKMT |
|||||||||
| Phosphatase | Nvec_109357.AA | Subfamily.MTMR1.PD | 1372-1512 | 41 | 7.2e-42 | 130.9 | In-house | 5-146 (149) | Show / Hide |
Range on Protein: 1372-1512 Range on HMM: 5-146/149 Sequence Identity: 41% (58 aa) ACCPATDSpISFVQQVNESEWLHQLSAVMNVSNVLVDLIDIQGSSVMVCFEDGWDVTAQVVCLAEICLDSHYRSIEGFKTLIEKEWLGFGHRFTQRCNQV .. |..| ......|..||... ... . ..| .. . .||.| |||| |||. .|| . |||.||.|.||..||||||| |||.|..| ivypside-skwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighg ES--AQSGFTPVFLQFLDAVHQIMRQYPLSFEFNDHFLCTLAY . |.. .||||||.|.| |..||.| .||||..|| |. dknhadadrspvflqfidcvwqvtrqfptafefneeflitild |
|||||||||
| Phosphatase | Nvec_109357.AA | Family.Myotubularin.PD | 1382-1513 | 39 | 9.8e-49 | 153.0 | In-house | 6-139 (141) | Show / Hide |
Range on Protein: 1382-1513 Range on HMM: 6-139/141 Sequence Identity: 39% (53 aa) SFVQQVNESEWLHQLSAVMNVSNVLVDLIDIQGSSVMVCFEDGWDVTAQVVCLAEICLDSHYRSIEGFKTLIEKEWLGFGHRFTQRCNQVES--AQSGFT ..........||.......... .|. .. ...||.| |||| |||.. ||...||..||.||||. ||||||| |||.|..|. . .. ... . kwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdkseseeers PVFLQFLDAVHQIMRQYPLSFEFNDHFLCTLAYH ||||||.|.|.|...|.| .||||..|| ... | Pvflqfidcvyqltkqfptafefnesflikildh |
|||||||||
| Phosphatase | Nvec_109357.AA | Subfamily.MTMR3.PD | 1384-1513 | 45 | 1.3e-44 | 139.8 | In-house | 2-133 (135) | Show / Hide |
Range on Protein: 1384-1513 Range on HMM: 2-133/135 Sequence Identity: 45% (59 aa) VQQVNESEWLHQLSAVMNVSNVLVDLIDIQGSSVMVCFEDGWDVTAQVVCLAEICLDSHYRSIEGFKTLIEKEWLGFGHRFTQRCNQVESA--QSGFTPV . ......||..||.... . .|. .| .| |.| |||| |.|.|.||...|| .||..|||| |.|.||| |||.|..|| . |. .. .||| lsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercpv FLQFLDAVHQIMRQYPLSFEFNDHFLCTLAYH ||.||.|||. .|.| |||||. || |. | flqwldcvhqlkkqfptsfefneaflvklvqh |
|||||||||
| Phosphatase | Nvec_109357.AA | Subfamily.C2-MTMR1.PD | 1381-1513 | 38 | 2.5e-37 | 116.3 | In-house | 4-135 (137) | Show / Hide |
Range on Protein: 1381-1513 Range on HMM: 4-135/137 Sequence Identity: 38% (51 aa) ISFVQQVNESEWLHQLSAVMNVSNVLVDLIDIQGSSVMVCFEDGWDVTAQVVCLAEICLDSHYRSIEGFKTLIEKEWLGFGHRFTQRCNQVESAqSGFTP . .. |.....|| ..||.. .. . .. . | .| |||| |.|.| ||.. || .||.|.|.. ||||||| |||.| .| . .|. | .| vqwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggadsv-sersp VFLQFLDAVHQIMRQYPLSFEFNDHFLCTLAYH .|||||| ..|. .|.| .||.. ..| || . iflqfldclyqvtkqfpsafeytarlllklady |
|||||||||
| PH | Nvec_109357.AA | PH | 1745-1845 | 24 | 5.1e-14 | 53.81 | SMART | 1-77 (82) | Show / Hide |
Range on Protein: 1745-1845 Range on HMM: 1-77/82 Sequence Identity: 24% (25 aa) QLHCGYLHKRGHLFKQWKSRWFVLDTQRNQLRYYETRDDPHCAGFIDLGEMIAVVPGNPLPGAPKGAEKGAFFDLRTTKRVYNLLAEDQEATQEWIEKLQ ...|.|.|.. . .|| |||||.. ..| ||. . . |.|.| ... .. | ... .|.| . .|..| |||.. .| VIKEGWLYKKS--K-RWKKRWFVLFN--DCLYYYKDK---KPKGSIPLSDCTVRE-P--------------CFEIHH-DRTYYFQCESEEEMQEWMQAIQ S . K |
|||||||||
| PH | Nvec_109357.AA | PH | 1745-1845 | 30 | 7.4e-14 | 52.62 | Pfam | 1-89 (92) | Show / Hide |
Range on Protein: 1745-1845 Range on HMM: 1-89/92 Sequence Identity: 30% (31 aa) QLHCGYLHKRGHLFKQWKSRWFVLDTQRNQLRYYETRDDPHCAGFIDLGEMIAVVPGNPLPGAPKGAEKGAFFDLRTTKR-VYNLLAEDQEATQEWIEKL ..|.|||.| .|.|| ||||| . |.| ||. .. . | |.| .. . . .. .. | .|| | .| . ||..| ..|.. . VIKEGWLHKKG-KRKSWKKRWFVLFN--NCLYYYKDDK-YRPKGSIPLSDCQVTKVPDN--------KRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAI QS || QS |
|||||||||
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Nvec_109357.AA | Protein | None | 1845 | None | Fasta, JSON |
| Nvec_109357.NA | RNA | None | 5535 | None | Fasta, JSON |