Gene Nvec_235730
Nvec_235730
Species: N.vectensis
Alias: Nvec_235730
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Nvec_235730.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Myotub-related | Nvec_235730.AA | Myotub-related | 156-272 | 49 | 5.1e-65 | 227.11 | Pfam | 1-121 (121) | Show / Hide |
Range on Protein: 156-272 Range on HMM: 1-121/121 Sequence Identity: 49% (60 aa) YELCDTYPNILYVPKSATKEVLVGSSRFRSRGRLPVLSFYHKSTQAAVCRCSQPLGGF-KGRCPEDEQMIQALLNSNP---NSKFIYIVDTRPRLNALAN ||.|.||| .|.||||.. ..|.....|||.||.|||. .|....|. ||||||| |. .|| |||...||....|. .|...||||.||..||.|| YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANADMIQSRKMYIVDARPYTNAMAN RAAGKGYESEDFYENVKFQFV ||.|.|||.|. | | .|.|. RAKGGGYENEEHYPNWEFVFM |
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| Phosphatase | Nvec_235730.AA | Family.Myotubularin.PD | 301-434 | 59 | 1e-63 | 202.1 | In-house | 6-141 (141) | Show / Hide |
Range on Protein: 301-434 Range on HMM: 6-141/141 Sequence Identity: 59% (80 aa) AFYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQS--DQKEFS ..| ||...||.||| .|...| |...| || ||||||||||||||| .|||...||||||||.||.||||||||||||||..|.| .. ...| || kwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdkseseeers PVFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVY |||||.....|| .||| .|.|||.||....||.| Pvflqfidcvyqltkqfptafefnesflikildhly |
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| Phosphatase | Nvec_235730.AA | Subfamily.MTMR1.PD | 296-434 | 57 | 2.4e-57 | 181.8 | In-house | 9-149 (149) | Show / Hide |
Range on Protein: 296-434 Range on HMM: 9-149/149 Sequence Identity: 57% (80 aa) KTPAGAFYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSD-- .. ..| ||...||.||| ||. .| ||..| ||.||.|||||||||||| ||| ..||.|||||.||.||||||||||||||..|| . . . sideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknha QKEFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVY .. |||||||....||. .||| .|.|||.||.|. ||.| dadrspvflqfidcvwqvtrqfptafefneeflitildhly |
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| Phosphatase | Nvec_235730.AA | Subfamily.MTMR3.PD | 302-434 | 56 | 1.8e-56 | 178.7 | In-house | 1-135 (135) | Show / Hide |
Range on Protein: 302-434 Range on HMM: 1-135/135 Sequence Identity: 56% (74 aa) FYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQS--DQKEFSP |.| ||...||.|. .|...| ...|| |. ||||||||||||.| .|| ..|||||||..||.||.|.|||.|||||.|||| .|..| .|||| flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp VFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVY |.|....|| .||| ||.||| ||. | .| | vflqwldcvhqlkkqfptsfefneaflvklvqhty |
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| Phosphatase | Nvec_235730.AA | Subfamily.C2-MTMR1.PD | 302-433 | 53 | 1.2e-53 | 169.7 | In-house | 6-136 (137) | Show / Hide |
Range on Protein: 302-433 Range on HMM: 6-136/137 Sequence Identity: 53% (69 aa) FYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDqKEFSPVF ..| ||...|| .|| .|... ||. | | |||||||||||.| .|| ..||||||||.|..||||||||.||||| .| |.| | ||.||| wlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggadsv-serspif LQFLESIWQLLQQFPFSFQFNERFLLTLHDHV ||. ..|. .||| .|... |.|| | |.. lqfldclyqvtkqfpsafeytarlllkladys |
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| FYVE | Nvec_235730.AA | FYVE | 611-678 | 27 | 1.2e-10 | 42.61 | SMART | 1-81 (81) | Show / Hide |
Range on Protein: 611-678 Range on HMM: 1-81/81 Sequence Identity: 27% (22 aa) AIKWKSVRD--VSQC-STCSLPIAF-LSRKYHCWNCGEVFCRRCIERQCSLPAHYSEN---------TVPVCKQCYKRIQH |.. ..| |. | . |. . | ..|. || .|| .||..| .... || . . | ||. || ...| ETKPHWQPDEEVDHCCMNCRKEFNFVTNRRHHCRHCGRIFCSKCCNKWIPLPYMGNYKKNGNNQNFTPVRVCDDCYEMMHH |
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| Phosphatase | Nvec_235730.AA | PTPc_motif | 265-434 | 8 | 1e-07 | 32.89 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 265-434
Range on HMM: 1-92/92
Sequence Identity: 8% (15 aa)
ENVKFQFVGIENI-----HVMRQSLFKMLEVVGESPKTPAGAFYSGLEASNWLKHIKNILDTSVFIAKAVAMEKASVLVHCSDGWDRTAQTCSLASIILD
. ... . . .| .|. .... | . ...||||.|..||.. |.. ... .
TVHHYHYTNWPDHVEKDSGVPEDSILEFIRHVRK-----------------------------------------PIVVHCSAGCGRTGTFCAIDMMMQQ
PYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQKEFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLHDHVY
. ... .... .| |...| .| .. . . .
------------------------------------------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE
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| Phosphatase | Nvec_235730.AA | Subfamily.DSP3.PD | 303-357 | 31 | 4e-07 | 18.6 | In-house | 57-112 (148) | Show / Hide |
Range on Protein: 303-357 Range on HMM: 57-112/148 Sequence Identity: 31% (18 aa) YSGLEASNWLK-HIKNILDT-SVFIAKAVAMEKASVLVHCSDGWDRTAqTCSLASII | |.|.|. . .... .. . ||..|.. ... ||||| | |.| |. || .. ylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsa-tlvlayLm |
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| Phosphatase | Nvec_235730.AA | Subfamily.R_Nematode_3.PD | 303-374 | 27 | 4.7e-07 | 18.0 | In-house | 172-228 (267) | Show / Hide |
Range on Protein: 303-374 Range on HMM: 172-228/267 Sequence Identity: 27% (20 aa) YSGLEASNWLKHIKNILDtsvfIAKAVAMEKASVLVHCSDGWDRTAQTCSlasiildpyyrTIHGFQVLIEK |.| ...| .. |..|. ..|.| |..|.|||||| |.| . .. |.| .|.. ykgWkelnapeepkeale----likfveksktpvvVHCsdGisRsatlaa-----------ielgyqliiks |
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| FYVE | Nvec_235730.AA | FYVE | 612-678 | 30 | 4.5e-18 | 64.5 | Pfam | 1-71 (71) | Show / Hide |
Range on Protein: 612-678 Range on HMM: 1-71/71 Sequence Identity: 30% (22 aa) IKWKSVRDVSQCSTCSLPIAFL-SRKYHCWNCGEVFC--RRCIERQCSL--PAHYSENTVPVCKQCYKRIQH .|. .|..|. |. | |. |. || .|| .|| | ...|.. |...... | ||. ||. .|. PHWQPDSEVTHCMICQKPFTFFGRRRHHCRHCGRIFCDDSKCSSHKCIPHPPYYGWNKPVRVCD-CYDDLQK |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Nvec_235730.AA | Protein | None | 681 | None | Fasta, JSON |
| Nvec_235730.NA | RNA | None | 2043 | None | Fasta, JSON |