nvec_116873
Species: N.vectensis
Alias: nvec_116873
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: EYA
Subfamily: EYA
Protein domain

Protein domains of nvec_116873.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_116873.AA Family.EYA.PD 20-266 80 4.2e-155 501.8 In-house 1-247 (247) Show / Hide
Range on Protein: 20-266
Range on HMM: 1-247/247
Sequence Identity: 80% (199 aa)

ERIFIWDLDETIIIFHSLLTGLFATKFGKDSPSSVALGLRMEEMIFNLADTHMFFNDLEDCDQVHIDDVAADDNGLDLSTYNFEADGFHAAATSANLCMA
||.|.|||||||||||||||| .|.|.|||..||||||||||||||||||||.||||||.|||||||||..|||| |||||||..|||||||||||||.|
ervfvwdldetiiifhslltgsyaekygkdasssvalglrmeemifnladthlffndleecdqvhiddvssddngqdlstynfatdgfhaaatsanlcla

TGVRGGVDWMRKLAYRYRKIKEVYSSYRNNVGGLLGAAKRETWLQLRMELESTTDSWLTLALKALSIIHSRTNCLNIMVTTTQLVPALAKSLLYGLGALF
||||||||||||||.||||.||.|.||.||||||||.||||.|||||.|.|..|||||||||||||.|.||.||.|..||||||||||||.||||||..|
tgvrggvdwmrklafryrkvkeiynsyknnvggllgpakreawlqlraeiealtdswltlalkalslissrsncvnvlvtttqlvpalakvllyglggvf

PIENIYSATKIGKEACFERILNRFGKKCTYIVVGDGRDEETASRQMN
||||||||||||||.|||||..|||.|.||.|.|||.|||||....|
pieniysatkigkescferivarfgrkvtyvvigdgkdeetaakkln

Phosphatase nvec_116873.AA Subfamily.EYA.PD 20-266 80 4.2e-155 501.8 In-house 1-247 (247) Show / Hide
Range on Protein: 20-266
Range on HMM: 1-247/247
Sequence Identity: 80% (199 aa)

ERIFIWDLDETIIIFHSLLTGLFATKFGKDSPSSVALGLRMEEMIFNLADTHMFFNDLEDCDQVHIDDVAADDNGLDLSTYNFEADGFHAAATSANLCMA
||.|.|||||||||||||||| .|.|.|||..||||||||||||||||||||.||||||.|||||||||..|||| |||||||..|||||||||||||.|
ervfvwdldetiiifhslltgsyaekygkdasssvalglrmeemifnladthlffndleecdqvhiddvssddngqdlstynfatdgfhaaatsanlcla

TGVRGGVDWMRKLAYRYRKIKEVYSSYRNNVGGLLGAAKRETWLQLRMELESTTDSWLTLALKALSIIHSRTNCLNIMVTTTQLVPALAKSLLYGLGALF
||||||||||||||.||||.||.|.||.||||||||.||||.|||||.|.|..|||||||||||||.|.||.||.|..||||||||||||.||||||..|
tgvrggvdwmrklafryrkvkeiynsyknnvggllgpakreawlqlraeiealtdswltlalkalslissrsncvnvlvtttqlvpalakvllyglggvf

PIENIYSATKIGKEACFERILNRFGKKCTYIVVGDGRDEETASRQMN
||||||||||||||.|||||..|||.|.||.|.|||.|||||....|
pieniysatkigkescferivarfgrkvtyvvigdgkdeetaakkln

Phosphatase nvec_116873.AA Group.HAD.PD 21-248 19 4.4e-39 122.3 In-house 2-190 (190) Show / Hide
Range on Protein: 21-248
Range on HMM: 2-190/190
Sequence Identity: 19% (44 aa)

RIFIWDLDETIIifhslLTGLFATKFGKDSPSSVALGLRMeemifNLADTHMFFNDLEDCDQVHIDDVAaddngldlstynFEADGFHAAA---------
. ...|||....     |.| .... |..|. .|...|..     | ......... . ........|.            . .|.|....|... . |.
dtlvlDldgvlw-----lhgspepleglrskgkvlifltn-----natksrlyllkrlallgflveeve------------phldeflervgelyelvvf

TSANLCMATGVRGGVDWMrKLAYRYRKIKEVYSSYRNnVGGLLGAAKRetwlqlrmelestTDSWLTLALKALSIIHSRTNCLNIMVtttqlvpALAKSL
 |.|.||.. ..|..|||...... ... .|.||.|..|             ....|. .|....||. . .. .. .. .. |..|      |..|..|
tagtreyadpvvgavdvg-deafsyrklrdacvylkg-pgalllatnr-------------dlgalvrdlekvviidnkpsvfafec-------npenal

LYGLGalfpIENIYSATKIGKEACFERILNRFGKKCT
...|.. ..|.| .||||...                
migdf----iddildaellglipdlenidvrfgkdvg

Phosphatase nvec_116873.AA Hydrolase 20-266 10 6e-06 21.85 Pfam 1-167 (167) Show / Hide
Range on Protein: 20-266
Range on HMM: 1-167/167
Sequence Identity: 10% (28 aa)

ERIFIWDLDETIIIF----HSLLTGLFATKFGKDSPSSVALGLRMEEMIF-NLADTHMFFNDLEDCDQVHIDDVAADDNGLDLSTYNFEADGFHAAATSA
 . ...|.| |.. .    |   .  .| ..|.  |  ..  .  ... . . .|..  . ..                                     
IKAVVFDKDGTLTDGSEHPHAQAWVEAAREYGY-WPFEEVEYIWGRGI-GDRIIDWWRATDEHI------------------------------------

NLCMATGVRGGVDWMRKLAYRYRKIKEVYSSYRNNVGGLLGAAKRETWLQLRMELESTTDSWLTLALKALSIIHSRTNCLNIMVTTTQLVPALAKSLLYG
                                                   . ... . | ..  | .||  .... ..  .|.| .   .| |.  ..|
------------------------------------------------D-EYLGVIAD-DQPYPGAREALQALKRM-GIKVAMITNDNR-NAQAVLEHLG

LGALFPIENIYSATKI---GKEACFERILNRFGKKCT---YIVVGDGRDEETASRQMN
.. .| .  ... ..|    .  ..|... |.|.|     ...||||     . .| .
IA-YFDHIIDSDDVGIVGKPHPEMYEKACQRLGVKPHECGCMMVGDGINDDPMLAQAG

Sequence
Name Sequence Type Origin Length Description Download
nvec_116873.AA Protein None 290 None Fasta, JSON
nvec_116873.NA RNA None 870 None Fasta, JSON
nvec_116873.AA.PD_20-266 Protein Phosphatase Domain None 247 None Fasta, JSON