Gene nvec_108213
nvec_108213
Species: N.vectensis
Alias: nvec_108213
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_108213.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_108213.AA | Subfamily.FCP1.PD | 148-293 | 60 | 9.9e-70 | 222.6 | In-house | 1-150 (150) | Show / Hide |
Range on Protein: 148-293 Range on HMM: 1-150/150 Sequence Identity: 60% (90 aa) RKLALVVDLDQTLIHTTVQ---LVPA-NMKDVQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIRSRDDC |||.|||||||||||||.. |.. ..||...| || ....|..|.||....||.|..|.|||||.|||||.||..||..|||. .||.|| |||... rklvLvvDlDqtlihttkdptievkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrdel FNAFSKFNDLRSLFPCGDSMVCIIDDRADVWNNAPSLIKVKPYQFFKGVG ||.||...|..|||.|||||.|||||.||||.|..|||||||.|||||| lnassktkklkklfptgdsmvviiDDredvWnfaenlikvkpykfFkgvg |
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| Phosphatase | nvec_108213.AA | CPDc | 148-293 | 34 | 7.2e-54 | 186.19 | SMART | 1-173 (173) | Show / Hide |
Range on Protein: 148-293 Range on HMM: 1-173/173 Sequence Identity: 34% (59 aa) RKLALVVDLDQTLIHT------------TVQLVPANMKDVQHF-----------VLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIAR .|. ||.|||.||.|. . .. ... .|. .. . .|||.....|.|| .| ||....|.||.|.||||.||||..... KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD MLDPDLSLFGYRIRSRDDCFNAFSK-FN-DLRSLFPC-GDSMVCIIDDRADVWNNAP-SLIKVKPYQFFKGVG ||||. .|.||. .||.|.. ..| .. |. ||... .|||.||||. |.|. | .|..||. .|.. . MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT |
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| Phosphatase | nvec_108213.AA | Family.FCP.PD | 148-287 | 37 | 1.8e-41 | 130.8 | In-house | 1-139 (164) | Show / Hide |
Range on Protein: 148-287 Range on HMM: 1-139/164 Sequence Identity: 37% (53 aa) RKLALVVDLDQTLIHTtvQLVPANMKDVQ-HFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIRsRDDCFNA .|. ||.|||.||.|. .| | |..|.. .. . ........| ||....||.|... ||..|||..||.||...|..|||. .|| .|. ||.|.. kkklLVlDLdetLvhs--elkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrll-rdecvlv FSKF-NDLRSLfPCGDSMVCIIDDRADVWNNAP-SLIKVKPYQ .. .||..| ....|.|.||||. |.... | .||||... kgnyvkdLskl-grdlskviiiDdspdsyklnpdnaikvksfk |
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| Phosphatase | nvec_108213.AA | NIF | 150-300 | 26 | 7.7e-29 | 106.57 | Pfam | 1-163 (189) | Show / Hide |
Range on Protein: 150-300 Range on HMM: 1-163/189 Sequence Identity: 26% (46 aa) LALVVDLDQTLIHTT--VQLVPANMKDVQHFVLP----GHPMWYHTKF-RPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPD-LSLF--GYRI-- . || ||| ||.|.. . .. .. |..| |... .... || .. |||...|.||..|.|.....|| . ...||. .| .|. KTLVLDLDETLVHCNPWWEPPN-----WHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLIC RSRDDCF------NAFS-KFNDLRSLFPCG-D-SMVCIIDDRADVWNNAPSLIKVKPYQFFKGVGDINAPPD .|..| | . | ||. |... | | | |.|.....| . .|...|| .. . | . .|| WYREHCWLYRNGGNYYVKK--DLSILWYNRWDLSRVIIVDNSPHSWLQPDNGIPIPPY-WYGYH-DDDDSPD |
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| Phosphatase | nvec_108213.AA | Group.HAD.PD | 150-291 | 21 | 1.2e-20 | 63.4 | In-house | 2-166 (190) | Show / Hide |
Range on Protein: 150-291 Range on HMM: 2-166/190 Sequence Identity: 21% (34 aa) LALVVDLDQTLI--HTTVQLVPANMKDVQHFVLPG----HPMWYHTKFR----------PWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLF ||.|||..|. . .| . .|. ... | . .... ... | ...||... . |||..||.|||.||.......|..| ||. dtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdeaf GYRIRSRDDCFNAFsKFNDL-----RSLFPCGDSM-VCIIDDRADVWN---NAPSLIKVKPYqFFKG .. .. ....| ... | . |.|||....|.. | . . .... .. syrklrdacvylkg-pgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdf-iddi |
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| Phosphatase | nvec_108213.AA | Subfamily.DULLARD.PD | 150-277 | 28 | 1.6e-17 | 52.6 | In-house | 3-136 (172) | Show / Hide |
Range on Protein: 150-277 Range on HMM: 3-136/172 Sequence Identity: 28% (37 aa) LALVVDLDQTLIHTTV------QLVPANMKDVQHFVL-PGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIrSRDD ||.|||.||||.. .. . .|.. || .|. .. ||. ||....|.|.| ||| ....||.... .|| . ... | |..| ktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrry-yrqh CFNAFSKFNDLRSLFPCGDSMVCIIDDRADVWNNA ..|. || | |.|.|. . ... CtlesgkytkdlslvsedlssviilDnspvayrkn |
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| Phosphatase | nvec_108213.AA | Subfamily.HSPC129.PD | 149-254 | 25 | 2.2e-17 | 52.2 | In-house | 2-106 (164) | Show / Hide |
Range on Protein: 149-254 Range on HMM: 2-106/164 Sequence Identity: 25% (27 aa) KLALVVDLDQTLIHTTVQLVPANmKDVQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIrSRDDCFNAFS . .||.|||.||.|.... .. . ... . . . . . ||....||....| .|. .|| ...||. . .|||. |. .|.|. | ... efslvldldetlvhcslakleda-tlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrl-frehcvcvdg KF-NDLR ||. nyikdls |
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| Phosphatase | nvec_108213.AA | Subfamily.SCP.PD | 149-260 | 28 | 2.9e-14 | 42.0 | In-house | 2-108 (163) | Show / Hide |
Range on Protein: 149-260 Range on HMM: 2-108/163 Sequence Identity: 28% (32 aa) KLALVVDLDQTLIHTTVQLVPANmKDVQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDlSLFGYRIrSRDDCFNAfs | .||.|||.||.|.... |. . | . | . . ||. ..||.|... .|. .|| ||. .| .||. . . .|. |.|.. | kkclvldldetlvhssfkpvena-dfvvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkk-nvikarl-frescvfh-- KFNDLRSLFPCG | .. | | kgnyvkdlsrlG |
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| Phosphatase | nvec_108213.AA | Subfamily.TIM50.PD | 186-271 | 25 | 3.3e-09 | 25.9 | In-house | 23-106 (150) | Show / Hide |
Range on Protein: 186-271 Range on HMM: 23-106/150 Sequence Identity: 25% (22 aa) WYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPdLSLFGYRIRSRDDCFNAFSKFNDLRSLFPcGDSMVCIIDDRA . .| || ..||...|. .|. .|| . ..|. . ||| .| ||. . .. || .| | | ..| . GwrfkkrPgvdafleelaelfeivvftseqgltaaplidkldP-kqlimyrlfrdatkyvdGehvkdlsklnr-dlskvivvdldk |
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| BRCT | nvec_108213.AA | BRCT | 623-712 | 18 | 1.7e-07 | 32.14 | SMART | 1-93 (93) | Show / Hide |
Range on Protein: 623-712 Range on HMM: 1-93/93 Sequence Identity: 18% (19 aa) KDVLRGANIVFTG--VIPTNLQPEKSEIWQRTLALGARISNQIVTPKDGRKDEVTTHVVAARLGTEKAYR---------ALKAPGIKLVNPMWLSCCEER ....| ...|| . . ..|. . ..|.... .. . | . ||||.. . ...| .. . .| ||..|.| |. | .. MKPFKGCTFCITGDDIEGNFD-M-RDELKEMIEMHGGKVT-SVSRK---RC-PDTTHVIC-SPENPKYETWNRMMTKYMKAIAWGIWIVHPDWIWDCIKK W | W |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_108213.AA | Protein | None | 916 | None | Fasta, JSON |
| nvec_108213.NA | RNA | None | 2748 | None | Fasta, JSON |
| nvec_108213.AA.PD_148-300 | Protein Phosphatase Domain | None | 153 | None | Fasta, JSON |