Gene nvec_s15804
nvec_s15804
Species: N.vectensis
Alias: nvec_s15804
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_s15804.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_s15804.AA | PP2C | 1-154 | 26 | 2.1e-17 | 64.23 | Pfam | 1-170 (284) | Show / Hide |
Range on Protein: 1-154 Range on HMM: 1-170/284 Sequence Identity: 26% (46 aa) HVSSLMGSGPKKQ*CQDTCCMLENLG------NDTYFFAVYDGHGSSGREASQTANDYIS----SELEKFSHKGDLAKL*SEKEVENYLSKIFKN--AEK . .... . .. . |... . |.. .. .||||.|||| |..|.. . . |.. . .. . | ||. |.| | . . WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHG--GHQAAKYCRKHLHKAMNTILKERKSFPEGNP----KDVEQALRKSFLECDTDM KLKS---SGID-----YSSSGTCAVSILLQGNK--CFIANLGDSRAVLFRVTPKEKLAIELSYDHKPIRPDERERI ...| . ..||..||.......| ..||.||||||| | . . .|.||||| ..|||.|| MFYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRI |
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| Phosphatase | nvec_s15804.AA | Group.PPM.PD | 11-154 | 33 | 1.2e-35 | 113.0 | In-house | 50-200 (459) | Show / Hide |
Range on Protein: 11-154 Range on HMM: 50-200/459 Sequence Identity: 33% (54 aa) KKQ*cQDTCCMLENLGNDTYFFAVYDGHGssGREASQTANDYISSELEKFSHK-GDL------------AKl*SEKEVENYLSKIFKNAEKKLKSSGIDY |.. .|.... ||..|.. ||.|.|||| |.||.. | . ... | | | |. . ....|.. | . |.. ...|...... kem--EDrhvivenfdnndsffgVfDGHg--GaeaaefaakkLpkilkkqlkkkkdevskksaeasldndd--rgekvkkalrsafleldedlseeanek S----SSGTCAVSILLQGNKCFIANLGDSRAVLFrvtpKEKLAIELSYDHKPIRPDERERI .|||.||..|..|.| ..||.||||||| ... |..||.|||| .|.||||| eepgkdsGtTAvvalingkklyvANaGDSravLc----rngkavplskdHkpenpeEreRI |
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| Phosphatase | nvec_s15804.AA | Family.PPM.PD | 10-154 | 37 | 4.2e-35 | 111.1 | In-house | 26-172 (495) | Show / Hide |
Range on Protein: 10-154 Range on HMM: 26-172/495 Sequence Identity: 37% (58 aa) PKKQ*cQDTCCMLENLGN--DTYFFAVYDGHGssGREASQTANDYISSELEKFSHKGDLAK--------L*seKEVENYLSKIFKNAEKKLKSSGIDYS- ... .|.....|||.| |...|.|.|||| |.||.. | . . . |.| | | .| ..|.. | | |.. ...|.....| . rsem--eDahvvvenlennedfslfgvfDGhg--Gaeaaefaakklhkilkkqlekkddeksstsaessa---ekvkealrkafleldeelseelneksa --SSGTCAVSILLQGNKCFIANLGDSRAVLFrvtpKEKLAIELSYDHKPIRPDERERI |||.||..|..|.|...||.|||||||. ... |.|||.|||| .|.||||| gkdsGtTAvvvlirgkklyvAnaGDsravLc----rngkavelskdHkpenpeEreRI |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1A.PD | 22-154 | 32 | 6.2e-23 | 71.5 | In-house | 34-163 (309) | Show / Hide |
Range on Protein: 22-154 Range on HMM: 34-163/309 Sequence Identity: 32% (45 aa) LENLGNDTYFFAVYDGHGssGREASQTANDYISSELEKF-SHKGDLAKL*SEKEVENYLSKIFKNAEKKLKsSGIDYS----SSGTCAVSILLQGNKCFI |.. .| ||||.|||. |...|... . . ... . ..|. | |...|.. |.| | ....|.. . .. | ||. ||..|.. .|... lpsklkdwsffavfDGHa--Gskvskycakhlleaileeeefkaskeks-skekvkealrkgfLelDekir-klvelskgedksGsTavvvlvspkklyl ANLGDSRAVLFRvtpkEKLAIELSYDHKPIRPDERERI ||.|||||||.| .. .. ..||||..|.|.||| ancGDsRavlsr----ngkvvfateDHkpsdpkEkeRi |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1G2.PD | 27-154 | 31 | 9e-22 | 67.5 | In-house | 41-156 (275) | Show / Hide |
Range on Protein: 27-154 Range on HMM: 41-156/275 Sequence Identity: 31% (40 aa) NDTYFFAVYDGHGssGREASQTANDYISSELEKfshKGDLAkl*sEKEVENYLSKIFKNAEKKLKSS-GIDYSSSGTCAVSILLQGNKCFIANLGDSRAV ... .|||.|||| |..... | . . ..| | ... | ..|. | . |.. ...| . .. .|.|. ||..|.. .| ..|| |||||| kslalfavfDGhG--Gakvakyagkklikkiak---kksfk----egaleqilkdafletDeellkdeklkdesaGstavvvlikeeklyvanaGDsrav LFRVTPkeklAIELSYDHKPIRPDERERI | . . ||.|||| . .|..|| lsskgn----vkalsfDhkPqeesekkri |
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| Phosphatase | nvec_s15804.AA | Subfamily.ILKAP.PD | 29-154 | 29 | 3.2e-21 | 65.9 | In-house | 47-178 (298) | Show / Hide |
Range on Protein: 29-154 Range on HMM: 47-178/298 Sequence Identity: 29% (40 aa) TYFFAVYDGHgsSGREASQTANDYISSELEKFSHKGDLAKl*SEKEVENYLSKIFKNAEKKLKSSG---IDYSSSGTCAVSILLQGNKCFIANLGDSRAV ..||.||| .|..||. |.. . . . . | |... .||.. | . ||...... . .|. ||..|. .|. ..||||||.||| vsyyavfDGh--aGsrasefaaeklhkviveklpkedvsa--kdkeikkclvdafkktDeeflklaskakPvWkdGstavvvlvvdnvlyvanlGDskav LFRVTPKEK-------LAIELSYDHKPIRPDERERI | .. . .. ||.||.| .||.|| laRakeegdkagestiasvlLskdHtpasyeerkri |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1K.PD | 21-154 | 38 | 1.7e-20 | 63.4 | In-house | 29-155 (264) | Show / Hide |
Range on Protein: 21-154 Range on HMM: 29-155/264 Sequence Identity: 38% (53 aa) MLENLGNDTYFFAVYDGHGSSgreasqTANDYISSELEKFSHKGDlAkl*SEKEVENYLSKIFKNAEKKLKS------SGIDYSSSGTCA-VSILLQGNK | .| .| ..|||.|||| | .| |.. .||. .. ||..|. | . |.. .||||. . .. |||| |||.| .||. klkeldpdllyfavfdGhgGs------saadfvhdkleeivrrll-e---kekdleevlkqafeeldkklkrylefsvaeaellssGttatvsllrdGne CFIANLGDSRAVLFRVTPKEKlaieLSYDHKPIRPDERERI .|.||||||.| | .| |. ||.| | .|.||| lvlaslGdsrailcrnGkakk----ltkdhdPerkeekeri |
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| Phosphatase | nvec_s15804.AA | Subfamily.LRR-PP2C.PD | 27-154 | 33 | 5.1e-20 | 61.9 | In-house | 39-150 (257) | Show / Hide |
Range on Protein: 27-154
Range on HMM: 39-150/257
Sequence Identity: 33% (42 aa)
NDTYfFAVYDGHGssGREASQTANDYISSELEKFShkgDLAKl*seKEVENYLSKIFKNAEKKLKSSGidySSSGTCAVSILLQGNKCFIANLGDSRAVL
.. | .|..|||| ||.|.. | . . |... || . . ...| | .|. . ... . || |.|.|. ..|.|||.||||.||
dedy-yalfdGhg--Graaakfaseelykilaell---dlnn----anPlkslkkaykeistqiserp---kfiGttaasvliiedkvyianvGdsrvvl
FrvtPKEKLAIELSYDHKPIRPDERERI
|. | ||.|||| ..|..||
c---qkdgtakrlsldhkPseeseekri
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1E.PD | 22-154 | 31 | 7.2e-19 | 58.1 | In-house | 39-159 (269) | Show / Hide |
Range on Protein: 22-154 Range on HMM: 39-159/269 Sequence Identity: 31% (43 aa) LENLGNDT-YFFAVYDGHGssGREASQTANDYISSEL-EKFSHKGDLAkl*sekeveNYLSKIFKNAEKKLKSS-GIDYSSSGTCAVSILLQGNKCFIAN .| .... ||||.|||| | ||.. |. . . | .. . | | | . | . ||...... . . ||. ||..|..... ..| felkdekeraffavfDGHg--Gveaakyaaahlhellvrqeklkedpa---------ealkeafkltDerflqkaereklksGstavvvliekdqlyvaW LGDSRAVLFRvtpkEKLAIELSYDHKPIRPDERERI ||||.|.| | . |..| ||| |.||..|| lGDsqallvr----kgeavqlmkpHkPeredEkkRi |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1D.PD | 27-154 | 30 | 9.9e-18 | 54.4 | In-house | 39-170 (311) | Show / Hide |
Range on Protein: 27-154 Range on HMM: 39-170/311 Sequence Identity: 30% (42 aa) NDTYFFAVYDGHGssGREASQTANDYISSELEKFSHKgdLAKl*SEKEVENYLSKIFKNAEKKLK--------SSGIDYSSSGTCAVSILLQGNKCFIAN ... |.||.|||| |.||.. |.. . |...| .. |.. ....| . ... | . ....| ..| .|| | ......| ..|. aeaafvavfDGHG--GkeAakfarehlwsvikkqkkf--lss--epedvleAireaflatheamkkklaeWpktksgllstaGttasvviirreklyvah LGDSRAVLFRVTP--KEKLAIELSYDHKPIRPDERERI |||..|| | |. | || |||| |.|.||| vGDsgivlgvkepkekklrakeltkdHkPespeEkeri |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1L.PD | 22-154 | 35 | 3e-17 | 53.0 | In-house | 33-164 (273) | Show / Hide |
Range on Protein: 22-154 Range on HMM: 33-164/273 Sequence Identity: 35% (48 aa) LENLGNDT--YFFAVYDGHGssGREASQTANDYISSELEKFSHKGDLAKl*SEKEVENY----LSKIFKNAEKKLKSSGIDYSSSGTCAVSILLQGNKCF |.. |.| ||||.|||| | |.. |.| .. .. . . | .| ... |. .|. || |. . .|| |.|.|... .|| eediknktgesffavfdGhG--Gefaaefakdvlvkaiknklieldadk--entvpinfsklltdeilsvdekllekakraediaGttalialvqesdli IANLGDSRAVLFRvtpKEKLAIELSYDHKPIRPDERERI .|||| ||. |. || ||.|||| .. || || vanvGdsrGvlyd---krGkaiplsfdhkpqqvkerkri |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1G.PD | 92-154 | 46 | 2.5e-16 | 49.9 | In-house | 299-357 (482) | Show / Hide |
Range on Protein: 92-154 Range on HMM: 299-357/482 Sequence Identity: 46% (29 aa) SSGIDYSSSGTCAVSILLQGNKCFIANLGDSRAVLFRVtpkeKLAIELSYDHKPIRPDERERI .| . ||| || |..|.| ..|| ||||.|| | |..||.||||. . |.||| kseepGkdsGttavvaLvkgkklivanaGDsRcvlsrn----GkaldlsiDhkPeDeveleRi |
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| Phosphatase | nvec_s15804.AA | Subfamily.PDP.PD | 84-154 | 36 | 2.1e-11 | 33.8 | In-house | 149-220 (409) | Show / Hide |
Range on Protein: 84-154 Range on HMM: 149-220/409 Sequence Identity: 36% (26 aa) KNAEKKLKSSGIDYSSSGTCAVSILLQGNKCFIANLGDSRAVLFRVTPKE-KLAIELSYDHKPIRPDERERI |..||.|... .. . ||.||. |..|.. ..|| ||.|||| .. .. |..|| |. ..| ||| kleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRi |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1H.PD | 78-153 | 30 | 7e-11 | 31.6 | In-house | 141-211 (402) | Show / Hide |
Range on Protein: 78-153 Range on HMM: 141-211/402 Sequence Identity: 30% (23 aa) YLSKIFKNAEKKLKSSGIDYSSSGTCAV-SILLQGNKCFIANLGDSRAVLFrvtpKEKLAIELSYDHKPIrpDERER | . |.. ..... .| .| |.. . |. .| ..|| |||||.| ... |.|| |. | ||.| alesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailv----rkdeiiplsadftPe--teRqR |
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| Phosphatase | nvec_s15804.AA | Subfamily.TAB1.PD | 99-154 | 41 | 7.5e-11 | 31.5 | In-house | 136-191 (336) | Show / Hide |
Range on Protein: 99-154 Range on HMM: 136-191/336 Sequence Identity: 41% (23 aa) SSGTCAVSILLQGNKCFIANLGDSRAVLFRVTPKEKLAIELSYDHKPIRPDERERI | || || |. || ..||.|||||.| . .... . || || .|| .|. sgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRl |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPM1G.PD | 17-90 | 33 | 3.4e-07 | 19.8 | In-house | 26-90 (482) | Show / Hide |
Range on Protein: 17-90 Range on HMM: 26-90/482 Sequence Identity: 33% (25 aa) DTCCMLENLGNDTYFFAVYDGHGssGREASQtandYISSELEKFSHKGDLAKl*sEKEVENYLSKIFKNAEKKL |. .. .| .|| .|||||||| |.| .. |....| .. .. | | .||. |.. | . .||| DahncildldedtslfavyDGhG--Gkevak----ycakklPdllkeskayk---egdvekaleeaflkvDkkl |
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| Phosphatase | nvec_s15804.AA | Subfamily.PPTC7.PD | 33-128 | 24 | 3.5e-06 | 16.9 | In-house | 39-129 (263) | Show / Hide |
Range on Protein: 33-128 Range on HMM: 39-129/263 Sequence Identity: 24% (24 aa) AVYDGHGS---SGREASQTANDYISsELEKFSHkgdlakl*SEKEVENYLSKIFKNAEKKLKSSGIDYSSSGTCAVSILLQGN-KCFIANLGDSRAVLFR .| || |. | ..|. .. .. ..|.... . |..|. ||...| ..|... . | |. . .| . . | |||||| . .| gVADgvggwreygidpsefskelmk-kcerivk--------eskfkerkpkkileaayqelleekvpvvGsstacivvldredkklesaNlGDSgflVvR |
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| Phosphatase | nvec_s15804.AA | PP2Cc | 1-154 | 12 | 7e-06 | -9.49 | SMART | 4-338 (338) | Show / Hide |
Range on Protein: 1-154
Range on HMM: 4-338/338
Sequence Identity: 12% (44 aa)
HVSSLMGSGP-------KKQ*CQDTCCMLENLGNDTYFFAVYDGHGSSGREASQTANDYISSELEKFSHKGDLAKL*-------------------SEKE
. | . .| .. ..| ... ||.|.|||| | |..| . . . . |... . . . ...
GYNSGWRYGYMESSMQGWRHPMEDAHVCRP-------FFGVFDGHG--GHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDKWFED
VENYLSKIFKNAEKKLKSSGIDYSSSGTCAVSILLQGNKCFIANLGDSRAVLFRVTP------KEKLAIELSYDHKPIRPDERER---------------
.|..| | |. ..... ..|| .|..||| ..||.|||||||.| . . |..|..|||| ..|||.|
WEDALRKAFLRMDEEI-----------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMPMHRQW
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VMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDI
------------------------------------------------------I
.
VRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAICDNMTVIVV
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_s15804.AA | Protein | None | 154 | None | Fasta, JSON |
| nvec_s15804.NA | RNA | None | 462 | None | Fasta, JSON |
| nvec_s15804.AA.PD_1-154 | Protein Phosphatase Domain | None | 154 | None | Fasta, JSON |