nvec_s8
Species: N.vectensis
Alias: nvec_s8
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: PPM_Unclassified
Protein domain

Protein domains of nvec_s8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase nvec_s8.AA PP2Cc 21-240 12 1e-05 -11.21 SMART 1-338 (338) Show / Hide
Range on Protein: 21-240
Range on HMM: 1-338/338
Sequence Identity: 12% (48 aa)

DLPVCKISGVGFLTNQRYREDGGRREEHEFEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTD---------------------
   ... ||. .      .|.      |. ||. . ..     ..|||||| | ..|......|. | |...|  ...|                     
HS-MGYNSGWRYGY----MESSMQGWRHPMEDAHVCRP-----FFGVFDGHGGHECAQYCRKHLH-EHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHD

---EEVQLVLRQAFFAVEKGFFQSIDDALAERTELQLQIPEGLSSYEAYKQYPRQVERIQELQEHISGGTTAVVLLHFNLLSFL----------------
   | .  .||.||..... .                                                .||||.|  .   .                 
KWFEDWEDALRKAFLRMDEEI------------------------------------------------CTAVVALIRGNKLYVANVGDSRAVLCRNGND

--------TPVQLSKDHDTQNEEELLRLARLGL------DIVQIQRN----RRIGS---QENTRSIGDYCVK----------------------------
        |..||..||   ||.|. |. ..|       ... .. |    |  |.   .. .|..||.. |                            
NWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVI

----------------GGYKDF------------------------------------------------------------------------DIL
                    ||                                                                         ..
AEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAICDNMTVIVV

Phosphatase nvec_s8.AA Subfamily.TAB1.PD 28-175 47 1.1e-46 149.1 In-house 2-148 (336) Show / Hide
Range on Protein: 28-175
Range on HMM: 2-148/336
Sequence Identity: 47% (70 aa)

SGVGFLTNQRYREDGGRREEHEFEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLtDDMTDEEVQLVLRQAFFAVEKGFFQSIDDALAE
||.|   |.||...| . |.||.||..|. . |.. ||.||||.|| ..|.|..||| ||||| .|  . ...|..|.| |..  ||. ||.|||||.||
sgiGisnneryskegsssedhenedkvfsrteddiilyavfdGydGekaaefveqrLvaelllgdl-seeaeaepkllllqvieeverkffesiddavae

RTELQLQIPEGLSSYEAYKQYPRQVERIQELQEHISGGTTAVVLLHFN
|..|. . |.|..|||....|.....|..||...||||||||| | .|
radlkstlpkgvasyeleekyeekinrlkeleseisgGttavvaliln

Phosphatase nvec_s8.AA Group.PPM.PD 37-232 26 5.4e-27 84.3 In-house 41-230 (459) Show / Hide
Range on Protein: 37-232
Range on HMM: 41-230/459
Sequence Identity: 26% (59 aa)

RYREDGGRREEHefEDRS-FHFNVDNT-CLYGVFDGHDGASVADFAAQRLPAeLLLQQLTDDMTD----------------EEVQLVLRQAFFAVEKGFF
. .. |.|.|.  |||  .. |.||. ...|||||| ||..|.|||..||   |..|| .  ..                |.|. .||.||...... ..
gvasmqgwrkem--EDrhvivenfdnndsffgVfDGHgGaeaaefaakkLpk-ilkkqlkkkkdevskksaeasldnddrgekvkkalrsafleldedls

QSIDDALaertelqlqipeglssyeaykqyprqveriqelQEHISGGTTAVVLLHFN--------------LLSFLTPVQLSKDHDTQNEEELLRLARLG
....                                  ......||||||.|  .              |     .|.||||| ..|.|||. ..|    
eeaneke---------------------------------epgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekag

-LdiVQIqRNRRIGSQENTRSIGDYCVKG
|.| ..|  |. . .|..||. .|     
Gs--vei-dgRvnGilavsRalGdhdlkk

Phosphatase nvec_s8.AA Subfamily.TAB1.PD 183-240 62 7.8e-26 80.6 In-house 174-231 (336) Show / Hide
Range on Protein: 183-240
Range on HMM: 174-231/336
Sequence Identity: 62% (36 aa)

VQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQENTRSIGDYCVKGGYKDFDIL
.||| || ..||.|| ||  ||||| ||..|.|.||.|.||||||| .|.|||. |.|
kQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvl

Phosphatase nvec_s8.AA Family.PPM.PD 38-232 25 5.1e-25 77.6 In-house 19-203 (495) Show / Hide
Range on Protein: 38-232
Range on HMM: 19-203/495
Sequence Identity: 25% (56 aa)

YREDGGRREEHefEDRS-FHFNVDN---TCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTD---------EEVQLVLRQAFFAVEKGFFQSIDDA
. .. |.|.|.  ||.  .  | .|   ..|.||||||.||..|.|||..|.  |. |.   | ..         |.|. .||.||..... . ......
vasmqgwrsem--eDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafleldeelseelnek

LaertelqlqipeglssyeaykqyprqveriqelqEHISGGTTAVVLLH--------------FNLLSFLTPVQLSKDHDTQNEEELLRLARLG--LDIv
                                   .. ..||||||.|                 | .   .|.||||| ..|.||  |. ..|  ..| 
s----------------------------------agkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvi-

qiQRNRRIGSQENTRSIGDYCVKG
  ...|  |. . .|..||. .| 
--rdgrvnGvlavsRalGdfdlkk

Phosphatase nvec_s8.AA Subfamily.PPM1K.PD 43-131 34 1.7e-10 30.4 In-house 19-102 (264) Show / Hide
Range on Protein: 43-131
Range on HMM: 19-102/264
Sequence Identity: 34% (31 aa)

GRREEHefEDRSFHFNVDNTCLY-GVFDGHDGASVADFAAQRLpaELLLQQLTDdmTDEEVQLVLRQAFFAVEKGFFQSIDDALAERTEL
|.|.|   |||    ..|.  || .||||| |.| |||. ..|  |  ...| .   ..... || |||  ..| . . .   .||...|
Gkraen--edrfklkeldpdllyfavfdGhgGssaadfvhdkl--eeivrrlle--kekdleevlkqafeeldkklkrylefsvaeaell

Phosphatase nvec_s8.AA Subfamily.PPM1G.PD 60-117 34 6.6e-10 28.6 In-house 36-90 (482) Show / Hide
Range on Protein: 60-117
Range on HMM: 36-90/482
Sequence Identity: 34% (20 aa)

DNTCLYGVFDGHDGASVADFAAQRLPAelLLQQLtDDMTDEEVQLVLRQAFFAVEKGF
..| |..|.||| |. || ..|..||   ||..      ...|.  |..||..|.| .
edtslfavyDGhGGkevakycakklPd--llkes-kaykegdvekaleeaflkvDkkl

Phosphatase nvec_s8.AA Subfamily.PPM1G2.PD 60-120 25 1.7e-09 27.0 In-house 41-98 (275) Show / Hide
Range on Protein: 60-120
Range on HMM: 41-98/275
Sequence Identity: 25% (15 aa)

DNTCLYGVFDGHDGASVADFAAQRLPAELLLqqlTDDMTDEEVQLVLRQAFFAVEKGFFQS
... |..||||| ||.|| .|...|   .       . ...... .|..|| .... . . 
kslalfavfDGhGGakvakyagkklikkiak---kksfkegaleqilkdafletDeellkd

Phosphatase nvec_s8.AA PP2C 182-237 25 1.9e-09 35.56 Pfam 152-208 (284) Show / Hide
Range on Protein: 182-237
Range on HMM: 152-208/284
Sequence Identity: 25% (15 aa)

PVQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQ--ENTRSIGDYCVKGGYKDF
..||..||. .||.|  |. ..|  . .. .. |.  .  ...|..||.. | ....|
VHQLTYDHKPSNEDERRRIRQAGGWVMWW-GFWRVNGVWLAVSRAFGDFHYKPNHTCF

Phosphatase nvec_s8.AA Subfamily.PPM1A.PD 53-116 22 2.3e-09 26.7 In-house 32-99 (309) Show / Hide
Range on Protein: 53-116
Range on HMM: 32-99/309
Sequence Identity: 22% (15 aa)

RSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQ----QLTDDMTDEEVQLVLRQAFFAVEKG
... ....  ...||||| |..|. ..|..| ...| .    . ... . |.|. .||..|.....  
idlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDek

Phosphatase nvec_s8.AA Subfamily.PPM1E.PD 60-120 31 1.5e-08 24.1 In-house 45-101 (269) Show / Hide
Range on Protein: 60-120
Range on HMM: 45-101/269
Sequence Identity: 31% (19 aa)

DNTCLYGVFDGHDGASVADFAAQRLPAeLLLQQLTdDMTDEEvqLVLRQAFFAVEKGFFQS
..   ..||||| |   |..||..|.  || .| . . .| .    |..|| .... | | 
keraffavfDGHgGveaakyaaahlhe-llvrqek-lkedpa--ealkeafkltDerflqk

Phosphatase nvec_s8.AA Subfamily.ILKAP.PD 59-120 30 3.1e-08 23.1 In-house 44-107 (298) Show / Hide
Range on Protein: 59-120
Range on HMM: 44-107/298
Sequence Identity: 30% (19 aa)

VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMT--DEEVQLVLRQAFFAVEKGFFQS
| .   |.||||| |   ..|||..|   .. .   .|..  |.|..  |..|| .... |.. 
vsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflkl

Phosphatase nvec_s8.AA Subfamily.PPM1D.PD 59-121 28 3.5e-08 22.8 In-house 38-100 (311) Show / Hide
Range on Protein: 59-121
Range on HMM: 38-100/311
Sequence Identity: 28% (17 aa)

VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTDEEVQLVLRQAFFAVEKGFFQSI
..   .||||| |   | || ..|  ..  |.      .|.|.  .|.||.|...   ..   
eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkl

Phosphatase nvec_s8.AA Subfamily.LRR-PP2C.PD 58-228 22 9.7e-08 21.5 In-house 36-179 (257) Show / Hide
Range on Protein: 58-228
Range on HMM: 36-179/257
Sequence Identity: 22% (38 aa)

NVDNTCLYGVFDGHDGASVADFAAQRLPAeLLLQQLTDDMTdeEVQLVLRQAFFAVEKGFfqsiddalaertelqlqipeglSSYEAYKQYPRQVERIQE
. ..  .| .|||| | . |.||...|.  .| . |    .  . . .|..|. ...  .                      | .  ..  | | .  |.
dksdedyyalfdGhgGraaakfaseelyk-ilaelldlnna--nPlkslkkaykeistqi----------------------serpkfiGttaasvliie

LQEHISG-GTTAVVLLhfnlLSFLTPVQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRI-GSQENTRSIGDY
  | . |||         | ..|| ||  ..|.| .|...||  .|. .   |. |    .|..||       
dkvyianvGdsrvvlc----qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds

Phosphatase nvec_s8.AA Subfamily.PPM1H.PD 39-174 22 3.3e-07 19.3 In-house 42-174 (402) Show / Hide
Range on Protein: 39-174
Range on HMM: 42-174/402
Sequence Identity: 22% (31 aa)

REDGGRREEHEFEDRSFHFNVDNTcLYGVFDGHDGASVADFAAQRLPAELlLQQLTD---DMTDEEVqlvLRQAFFAVEKGFFQSIDDALAERTELQLQI
..  . ||.| ...| . ... . ..|.|||| | ..|  |.. |   |  ..|.|    ......    ..|.   .|   .. ..|. ... .    |
svtskageeeelkekskeeklpla-yfglfDGhaGsgaalvaskllhkhl-kekledvlellleksa---eklalgeerkeaptepseifveekkiskee

-PEGlSSYEAYKQYPRQVERIQElQEHISGGTTAVVLLHF
 .  .|...   |..| .| . .|.|| ||.| | .    
LviG-alesaflemDeqiarere-ayrikGGCtalvalvl

Phosphatase nvec_s8.AA Subfamily.PPM1L.PD 50-109 26 3.4e-07 19.8 In-house 30-88 (273) Show / Hide
Range on Protein: 50-109
Range on HMM: 30-88/273
Sequence Identity: 26% (16 aa)

FEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAElLLQQLTDDMTDEEVQLVLRQA
||      |  .. ...||||| |   |.|| ..|. . ....| .  .| | .. .  .
feieediknktgesffavfdGhGGefaaefakdvlvka-iknklieldadkentvpinfs

Phosphatase nvec_s8.AA Subfamily.ILKAP.PD 181-231 37 4.7e-07 19.2 In-house 159-206 (298) Show / Hide
Range on Protein: 181-231
Range on HMM: 159-206/298
Sequence Identity: 37% (19 aa)

TPVQLSKDHDTQNEEELLRLARLGldiVQIQRNRRIGSQENTRSIGDYCVK
..|.|||||.. ..||  |. . |    ... .| .|. |  |||||   |
asvlLskdHtpasyeerkriqkaG---gvvrdgRvlGvlevsRsiGDgrfk

Phosphatase nvec_s8.AA Subfamily.PDP.PD 51-94 37 5e-06 15.9 In-house 24-69 (409) Show / Hide
Range on Protein: 51-94
Range on HMM: 24-69/409
Sequence Identity: 37% (17 aa)

EDRSF--HFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLT
||| .  ..   | .|.|||||| ||  |.   .||.  . .. | 
EDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllk

Sequence
Name Sequence Type Origin Length Description Download
nvec_s8.AA Protein None 240 None Fasta, JSON
nvec_s8.NA RNA None 720 None Fasta, JSON
nvec_s8.AA.PD_21-240 Protein Phosphatase Domain None 220 None Fasta, JSON