Gene nvec_s8
nvec_s8
Species: N.vectensis
Alias: nvec_s8
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_s8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_s8.AA | PP2Cc | 21-240 | 12 | 1e-05 | -11.21 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 21-240
Range on HMM: 1-338/338
Sequence Identity: 12% (48 aa)
DLPVCKISGVGFLTNQRYREDGGRREEHEFEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTD---------------------
... ||. . .|. |. ||. . .. ..|||||| | ..|......|. | |...| ...|
HS-MGYNSGWRYGY----MESSMQGWRHPMEDAHVCRP-----FFGVFDGHGGHECAQYCRKHLH-EHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHD
---EEVQLVLRQAFFAVEKGFFQSIDDALAERTELQLQIPEGLSSYEAYKQYPRQVERIQELQEHISGGTTAVVLLHFNLLSFL----------------
| . .||.||..... . .||||.| . .
KWFEDWEDALRKAFLRMDEEI------------------------------------------------CTAVVALIRGNKLYVANVGDSRAVLCRNGND
--------TPVQLSKDHDTQNEEELLRLARLGL------DIVQIQRN----RRIGS---QENTRSIGDYCVK----------------------------
|..||..|| ||.|. |. ..| ... .. | | |. .. .|..||.. |
NWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVI
----------------GGYKDF------------------------------------------------------------------------DIL
|| ..
AEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAICDNMTVIVV
|
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.TAB1.PD | 28-175 | 47 | 1.1e-46 | 149.1 | In-house | 2-148 (336) | Show / Hide |
Range on Protein: 28-175 Range on HMM: 2-148/336 Sequence Identity: 47% (70 aa) SGVGFLTNQRYREDGGRREEHEFEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLtDDMTDEEVQLVLRQAFFAVEKGFFQSIDDALAE ||.| |.||...| . |.||.||..|. . |.. ||.||||.|| ..|.|..||| ||||| .| . ...|..|.| |.. ||. ||.|||||.|| sgiGisnneryskegsssedhenedkvfsrteddiilyavfdGydGekaaefveqrLvaelllgdl-seeaeaepkllllqvieeverkffesiddavae RTELQLQIPEGLSSYEAYKQYPRQVERIQELQEHISGGTTAVVLLHFN |..|. . |.|..|||....|.....|..||...||||||||| | .| radlkstlpkgvasyeleekyeekinrlkeleseisgGttavvaliln |
|||||||||
| Phosphatase | nvec_s8.AA | Group.PPM.PD | 37-232 | 26 | 5.4e-27 | 84.3 | In-house | 41-230 (459) | Show / Hide |
Range on Protein: 37-232 Range on HMM: 41-230/459 Sequence Identity: 26% (59 aa) RYREDGGRREEHefEDRS-FHFNVDNT-CLYGVFDGHDGASVADFAAQRLPAeLLLQQLTDDMTD----------------EEVQLVLRQAFFAVEKGFF . .. |.|.|. ||| .. |.||. ...|||||| ||..|.|||..|| |..|| . .. |.|. .||.||...... .. gvasmqgwrkem--EDrhvivenfdnndsffgVfDGHgGaeaaefaakkLpk-ilkkqlkkkkdevskksaeasldnddrgekvkkalrsafleldedls QSIDDALaertelqlqipeglssyeaykqyprqveriqelQEHISGGTTAVVLLHFN--------------LLSFLTPVQLSKDHDTQNEEELLRLARLG .... ......||||||.| . | .|.||||| ..|.|||. ..| eeaneke---------------------------------epgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekag -LdiVQIqRNRRIGSQENTRSIGDYCVKG |.| ..| |. . .|..||. .| Gs--vei-dgRvnGilavsRalGdhdlkk |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.TAB1.PD | 183-240 | 62 | 7.8e-26 | 80.6 | In-house | 174-231 (336) | Show / Hide |
Range on Protein: 183-240 Range on HMM: 174-231/336 Sequence Identity: 62% (36 aa) VQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQENTRSIGDYCVKGGYKDFDIL .||| || ..||.|| || ||||| ||..|.|.||.|.||||||| .|.|||. |.| kQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvl |
|||||||||
| Phosphatase | nvec_s8.AA | Family.PPM.PD | 38-232 | 25 | 5.1e-25 | 77.6 | In-house | 19-203 (495) | Show / Hide |
Range on Protein: 38-232
Range on HMM: 19-203/495
Sequence Identity: 25% (56 aa)
YREDGGRREEHefEDRS-FHFNVDN---TCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTD---------EEVQLVLRQAFFAVEKGFFQSIDDA
. .. |.|.|. ||. . | .| ..|.||||||.||..|.|||..|. |. |. | .. |.|. .||.||..... . ......
vasmqgwrsem--eDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafleldeelseelnek
LaertelqlqipeglssyeaykqyprqveriqelqEHISGGTTAVVLLH--------------FNLLSFLTPVQLSKDHDTQNEEELLRLARLG--LDIv
.. ..||||||.| | . .|.||||| ..|.|| |. ..| ..|
s----------------------------------agkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvi-
qiQRNRRIGSQENTRSIGDYCVKG
...| |. . .|..||. .|
--rdgrvnGvlavsRalGdfdlkk
|
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1K.PD | 43-131 | 34 | 1.7e-10 | 30.4 | In-house | 19-102 (264) | Show / Hide |
Range on Protein: 43-131 Range on HMM: 19-102/264 Sequence Identity: 34% (31 aa) GRREEHefEDRSFHFNVDNTCLY-GVFDGHDGASVADFAAQRLpaELLLQQLTDdmTDEEVQLVLRQAFFAVEKGFFQSIDDALAERTEL |.|.| ||| ..|. || .||||| |.| |||. ..| | ...| . ..... || ||| ..| . . . .||...| Gkraen--edrfklkeldpdllyfavfdGhgGssaadfvhdkl--eeivrrlle--kekdleevlkqafeeldkklkrylefsvaeaell |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1G.PD | 60-117 | 34 | 6.6e-10 | 28.6 | In-house | 36-90 (482) | Show / Hide |
Range on Protein: 60-117 Range on HMM: 36-90/482 Sequence Identity: 34% (20 aa) DNTCLYGVFDGHDGASVADFAAQRLPAelLLQQLtDDMTDEEVQLVLRQAFFAVEKGF ..| |..|.||| |. || ..|..|| ||.. ...|. |..||..|.| . edtslfavyDGhGGkevakycakklPd--llkes-kaykegdvekaleeaflkvDkkl |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1G2.PD | 60-120 | 25 | 1.7e-09 | 27.0 | In-house | 41-98 (275) | Show / Hide |
Range on Protein: 60-120 Range on HMM: 41-98/275 Sequence Identity: 25% (15 aa) DNTCLYGVFDGHDGASVADFAAQRLPAELLLqqlTDDMTDEEVQLVLRQAFFAVEKGFFQS ... |..||||| ||.|| .|...| . . ...... .|..|| .... . . kslalfavfDGhGGakvakyagkklikkiak---kksfkegaleqilkdafletDeellkd |
|||||||||
| Phosphatase | nvec_s8.AA | PP2C | 182-237 | 25 | 1.9e-09 | 35.56 | Pfam | 152-208 (284) | Show / Hide |
Range on Protein: 182-237 Range on HMM: 152-208/284 Sequence Identity: 25% (15 aa) PVQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRIGSQ--ENTRSIGDYCVKGGYKDF ..||..||. .||.| |. ..| . .. .. |. . ...|..||.. | ....| VHQLTYDHKPSNEDERRRIRQAGGWVMWW-GFWRVNGVWLAVSRAFGDFHYKPNHTCF |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1A.PD | 53-116 | 22 | 2.3e-09 | 26.7 | In-house | 32-99 (309) | Show / Hide |
Range on Protein: 53-116 Range on HMM: 32-99/309 Sequence Identity: 22% (15 aa) RSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQ----QLTDDMTDEEVQLVLRQAFFAVEKG ... .... ...||||| |..|. ..|..| ...| . . ... . |.|. .||..|..... idlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDek |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1E.PD | 60-120 | 31 | 1.5e-08 | 24.1 | In-house | 45-101 (269) | Show / Hide |
Range on Protein: 60-120 Range on HMM: 45-101/269 Sequence Identity: 31% (19 aa) DNTCLYGVFDGHDGASVADFAAQRLPAeLLLQQLTdDMTDEEvqLVLRQAFFAVEKGFFQS .. ..||||| | |..||..|. || .| . . .| . |..|| .... | | keraffavfDGHgGveaakyaaahlhe-llvrqek-lkedpa--ealkeafkltDerflqk |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.ILKAP.PD | 59-120 | 30 | 3.1e-08 | 23.1 | In-house | 44-107 (298) | Show / Hide |
Range on Protein: 59-120 Range on HMM: 44-107/298 Sequence Identity: 30% (19 aa) VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMT--DEEVQLVLRQAFFAVEKGFFQS | . |.||||| | ..|||..| .. . .|.. |.|.. |..|| .... |.. vsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflkl |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1D.PD | 59-121 | 28 | 3.5e-08 | 22.8 | In-house | 38-100 (311) | Show / Hide |
Range on Protein: 59-121 Range on HMM: 38-100/311 Sequence Identity: 28% (17 aa) VDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLTDDMTDEEVQLVLRQAFFAVEKGFFQSI .. .||||| | | || ..| .. |. .|.|. .|.||.|... .. eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkl |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.LRR-PP2C.PD | 58-228 | 22 | 9.7e-08 | 21.5 | In-house | 36-179 (257) | Show / Hide |
Range on Protein: 58-228 Range on HMM: 36-179/257 Sequence Identity: 22% (38 aa) NVDNTCLYGVFDGHDGASVADFAAQRLPAeLLLQQLTDDMTdeEVQLVLRQAFFAVEKGFfqsiddalaertelqlqipeglSSYEAYKQYPRQVERIQE . .. .| .|||| | . |.||...|. .| . | . . . .|..|. ... . | . .. | | . |. dksdedyyalfdGhgGraaakfaseelyk-ilaelldlnna--nPlkslkkaykeistqi----------------------serpkfiGttaasvliie LQEHISG-GTTAVVLLhfnlLSFLTPVQLSKDHDTQNEEELLRLARLGLDIVQIQRNRRI-GSQENTRSIGDY | . ||| | ..|| || ..|.| .|...|| .|. . |. | .|..|| dkvyianvGdsrvvlc----qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1H.PD | 39-174 | 22 | 3.3e-07 | 19.3 | In-house | 42-174 (402) | Show / Hide |
Range on Protein: 39-174 Range on HMM: 42-174/402 Sequence Identity: 22% (31 aa) REDGGRREEHEFEDRSFHFNVDNTcLYGVFDGHDGASVADFAAQRLPAELlLQQLTD---DMTDEEVqlvLRQAFFAVEKGFFQSIDDALAERTELQLQI .. . ||.| ...| . ... . ..|.|||| | ..| |.. | | ..|.| ...... ..|. .| .. ..|. ... . | svtskageeeelkekskeeklpla-yfglfDGhaGsgaalvaskllhkhl-kekledvlellleksa---eklalgeerkeaptepseifveekkiskee -PEGlSSYEAYKQYPRQVERIQElQEHISGGTTAVVLLHF . .|... |..| .| . .|.|| ||.| | . LviG-alesaflemDeqiarere-ayrikGGCtalvalvl |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PPM1L.PD | 50-109 | 26 | 3.4e-07 | 19.8 | In-house | 30-88 (273) | Show / Hide |
Range on Protein: 50-109 Range on HMM: 30-88/273 Sequence Identity: 26% (16 aa) FEDRSFHFNVDNTCLYGVFDGHDGASVADFAAQRLPAElLLQQLTDDMTDEEVQLVLRQA || | .. ...||||| | |.|| ..|. . ....| . .| | .. . . feieediknktgesffavfdGhGGefaaefakdvlvka-iknklieldadkentvpinfs |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.ILKAP.PD | 181-231 | 37 | 4.7e-07 | 19.2 | In-house | 159-206 (298) | Show / Hide |
Range on Protein: 181-231 Range on HMM: 159-206/298 Sequence Identity: 37% (19 aa) TPVQLSKDHDTQNEEELLRLARLGldiVQIQRNRRIGSQENTRSIGDYCVK ..|.|||||.. ..|| |. . | ... .| .|. | ||||| | asvlLskdHtpasyeerkriqkaG---gvvrdgRvlGvlevsRsiGDgrfk |
|||||||||
| Phosphatase | nvec_s8.AA | Subfamily.PDP.PD | 51-94 | 37 | 5e-06 | 15.9 | In-house | 24-69 (409) | Show / Hide |
Range on Protein: 51-94 Range on HMM: 24-69/409 Sequence Identity: 37% (17 aa) EDRSF--HFNVDNTCLYGVFDGHDGASVADFAAQRLPAELLLQQLT ||| . .. | .|.|||||| || |. .||. . .. | EDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllk |
|||||||||
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_s8.AA | Protein | None | 240 | None | Fasta, JSON |
| nvec_s8.NA | RNA | None | 720 | None | Fasta, JSON |
| nvec_s8.AA.PD_21-240 | Protein Phosphatase Domain | None | 220 | None | Fasta, JSON |