Gene nvec_150220
nvec_150220
Species: N.vectensis
Alias: nvec_150220
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_150220.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_150220.AA | Family.PPTC7.PD | 37-299 | 54 | 4.2e-118 | 383.0 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 37-299 Range on HMM: 1-262/262 Sequence Identity: 54% (145 aa) AVCCGFSKDY--HTSKKRFAFGEDAYFITENLFSNVLAVA-CMSCCRTFFLLKLVAGSTSIKGVSRKLKinflDGRTCRMTTQQTMKTRIQPLLMFFFSR ||.|||.||. ..||||..|||||||...| ...||.|| .....|.... . ..|...| ..|..| .............|.... ||. ... avkcgfakdllkqkskkrskfGeDayFvssnkvadvlgvADgvggwreygvdssafsselmkkcerlvk----eskfkplkpkkllkaayaelleekvpv TGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRKGIVVHQSSEQQHYFNTPYQLAIPPPGQDGRVIQDSLDAAESTSFNVEVDDLIVMGTDGLFDNLSTDQ .||||||.||||..||.|.|.|||||||||||.|.|||.|.||||||||||||.|||...||.||.||..||.||||.|...|.|...|||.|||||.|| vGsstAcvvvldredkklesanlGDsgflvvRegkvvhrskeqqhyFntPyqLsipPeerdgkvisdspeaAdstsfevkkgDiillatDGvfDnlsedq ILTEIAELQDYDAESIQSLADSLAMKARCLAFDPSYESPFAKQAKLRGLAITGGKPDDITVLVAVV ||.|..||...|.|..|.||.|||.|||.|.|||.||||||..||.||||..|||||||||..||| ileelkelkerdeeelqllanslaekareLsfdpkyespFaqkakkrglaasGGKpDDitvvlavv |
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| Phosphatase | nvec_150220.AA | Subfamily.PPTC7.PD | 37-299 | 52 | 4.6e-115 | 373.0 | In-house | 2-263 (263) | Show / Hide |
Range on Protein: 37-299 Range on HMM: 2-263/263 Sequence Identity: 52% (140 aa) AVCCGFSKDY--HTSKKRFAFGEDAYFITENLFSNVLAVA-CMSCCRTFFLLKLVAGSTSIKGVSRKLKinflDGRTCRMTTQQTMKTRIQPLLMFFFSR .|.|||.||. ..||||..|||||||...| ...||.|| .....|.... . ......|...|. | .................|||. .... svvcgfakdllkqkskkrskfGeDayFvssnkvadvlgVADgvggwreygidpsefskelmkkcerivk----eskfkerkpkkileaayqelleekvpv TGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRKGIVVHQSSEQQHYFNTPYQLAIPPPGQDGRVIQDSLDAAESTSFNVEVDDLIVMGTDGLFDNLSTDQ |||||||||||..||.|.|.|||||||||||.| |||.|.||||||||||||.|||...||.||.|...||.||||.|...|||...|||.|||||.|.| vGsstacivvldredkklesaNlGDSgflVvRngkvvhrskeqqhyFNtPyqLsipPeerdgkvildkpeaadstsfevkkgDlillatDGvfDNlsede ILTEIAELQDYDAESIQSLADSLAMKARCLAFDPSYESPFAKQAKLRGLAITGGKPDDITVLVAVV |....||...|.|..|.||.|||.|||.|..||.|||||||.|| .|||..|||||||||..|.| ilevlkelkerdeeelqllanslaekarelsldpkyespFakkakknglaasGGKpDDitvvlalv |
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| Phosphatase | nvec_150220.AA | Group.PPM.PD | 212-307 | 18 | 1.1e-11 | 33.2 | In-house | 246-329 (459) | Show / Hide |
Range on Protein: 212-307 Range on HMM: 246-329/459 Sequence Identity: 18% (18 aa) VE-VDDLIVMGTDGLFDNLSTDQILTEIAELQDY----DAESIQSLADSLAMKARCLafdpSyespfakqaklrglA-ITGGKPDDITVLVAVVSEESSK .. |. .|...|||.| || .... ..| . . .. .. |..|...|. . .|...|.|||.| ...... lteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealak----g--------------stgdgtscDNiTvivvtlndamrr ET ql |
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| Phosphatase | nvec_150220.AA | Family.PPM.PD | 211-306 | 23 | 5.7e-09 | 24.1 | In-house | 221-293 (495) | Show / Hide |
Range on Protein: 211-306 Range on HMM: 221-293/495 Sequence Identity: 23% (23 aa) NVEVDDLIVMGTDGLFDNLSTDQILTEIAELQDYDAESIQSLADSLAMKArcLAFDPSyespfakqaklrglaitggkpDDITVLVAVVSEESSKE . | |. .|. .|||.| || .... . | . . |. ...| .| .| || . . |.||||| ..|. .. tqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdea--lakgsr---------------------DNiTvlvvalyenikqq |
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| Phosphatase | nvec_150220.AA | Group.PPM.PD | 133-174 | 29 | 6.3e-08 | 20.8 | In-house | 148-187 (459) | Show / Hide |
Range on Protein: 133-174 Range on HMM: 148-187/459 Sequence Identity: 29% (12 aa) RTGSSTACIVVLdkRDKTLHSVNLGDSGFLVVRKGIVVHQSS ... .||..... ..|.|. |.||| ...|.| .|. | kdsGtTAvvali--ngkklyvANaGDSravLcrngkavplsk |
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| Phosphatase | nvec_150220.AA | Subfamily.PPM1H.PD | 208-264 | 29 | 1.2e-07 | 20.1 | In-house | 319-379 (402) | Show / Hide |
Range on Protein: 208-264 Range on HMM: 319-379/402 Sequence Identity: 29% (17 aa) TSFNVEVDDLIVMGTDGLFDNLSTDQILTEIAE-LQDY---DAESIQSLADSLAMKARCLA |... . ||.....||||.| || ..... ..| |... | . ..| .| ..|| tqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkrytavaqeLvaaarGkl |
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| Phosphatase | nvec_150220.AA | PP2Cc | 37-297 | 10 | 5.6e-07 | 7.51 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 37-297
Range on HMM: 1-338/338
Sequence Identity: 10% (42 aa)
AVCCGFSKDYHTSK------KRFAFGEDAYFITENLFSNVLAVA-------CMSCCRTFFLLKLVAGSTSIKG---------------------------
|. .... .. .. .|||.... . .|. | || .. |. . |.
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP-----FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDKWFED
VSRKLKINFLDGRTCRMTTQQTMKTRIQPLLMFFFSRTGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRKGI---------VVHQSSEQQHY--------
. . |. || . .||....... . |. |.||| . |.| .|| .| ..
WEDALRKAFLRMDEEI------------------------CTAVVALIRGNK--LYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRR
--------------FNTPYQL---AIPPP---GQDGRVIQDS------------------------------LDAAESTSFN-------VEVDDLIVMGT
. ... ... . | . | . |. . .. ||......
IEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCC
DGLFDNLSTDQILTEIAE-----------------------LQDYDAESIQSLADSLAMKARCLAFDPSYESPFAKQAKLRGLAITGGKPDDITVLVA
|||.|..| ... . . . ... .. |. |...|. |..||.|
DGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHR-QKKHNDPMEAAKRLCDCAI---------------------------CDNMTVIVV
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| Phosphatase | nvec_150220.AA | Family.PPM.PD | 132-175 | 31 | 1.7e-06 | 15.9 | In-house | 119-160 (495) | Show / Hide |
Range on Protein: 132-175 Range on HMM: 119-160/495 Sequence Identity: 31% (14 aa) SRTGSSTACIVVLdkRDKTLHSVNLGDSGFLVVRKGIVVHQSSE .... .||..|.. |.|.|. |.||| ...|.| .|. | . gkdsGtTAvvvli--rgkklyvAnaGDsravLcrngkavelskd |
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| Phosphatase | nvec_150220.AA | Subfamily.PPM1E.PD | 209-261 | 20 | 2.7e-06 | 16.0 | In-house | 201-254 (269) | Show / Hide |
Range on Protein: 209-261 Range on HMM: 201-254/269 Sequence Identity: 20% (11 aa) SFNV-EVDDLIVMGTDGLFDNLSTDQILTEIAELQDYDAESIQSLADSLAMKAR .... . .|......|||.| . ...... . | .||. ...| .| .|. eveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaak |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_150220.AA | Protein | None | 309 | None | Fasta, JSON |
| nvec_150220.NA | RNA | None | 927 | None | Fasta, JSON |
| nvec_150220.AA.PD_37-299 | Protein Phosphatase Domain | None | 263 | None | Fasta, JSON |