Gene nvec_231431
nvec_231431
Species: N.vectensis
Alias: nvec_231431
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of nvec_231431.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | nvec_231431.AA | Subfamily.PPP6C.PD | 1-130 | 77 | 7.4e-77 | 248.1 | In-house | 142-271 (271) | Show / Hide |
Range on Protein: 1-130 Range on HMM: 142-271/271 Sequence Identity: 77% (101 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP .|.||.|... |.| ||.|.|..|||||||||||||||||.|.|||.||||||.||| |||.|||.||||||||||||||.||.||||||||||||||| lcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsap NYCYRCGNIASILAFSDADNREPKLFQAVP ||||||||||||||..||..||.|||.||| nycyrcgniasilaledaeereaklfkavp |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP4C.PD | 1-129 | 56 | 7.3e-60 | 192.4 | In-house | 142-270 (271) | Show / Hide |
Range on Protein: 1-129 Range on HMM: 142-270/271 Sequence Identity: 56% (73 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP .| || | | | ||.|||. |.||.|..|||.|||||....||.||||||.||| .|...|.. |...||||||||| ||||..|.||..|||||| fcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsap NYCYRCGNIASILAFSDADNREPKLFQAV ||||||||.|.|| . .. ... |.|.|. nycyrcgnvaaileldeeldkdfkifeaa |
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| Phosphatase | nvec_231431.AA | Family.PPP.PD | 1-131 | 41 | 3.4e-50 | 161.1 | In-house | 211-341 (349) | Show / Hide |
Range on Protein: 1-131 Range on HMM: 211-341/349 Sequence Identity: 41% (55 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP .| || |... .. | ||.|.|..|.|..|..|||.||||||.. |. ..||.|..|||.....|.. |||.||.|||..|.|||......||||..||| lcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsap NYCYRCGNIASILAFSDADNREPKLFQAVPD |||....|.|..| .... . . ..|..... nYcgeysnkaavlkvdknlklsivqfkpskh |
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| Phosphatase | nvec_231431.AA | Group.PPP.PD | 1-131 | 41 | 3.4e-50 | 161.1 | In-house | 211-341 (349) | Show / Hide |
Range on Protein: 1-131 Range on HMM: 211-341/349 Sequence Identity: 41% (55 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP .| || |... .. | ||.|.|..|.|..|..|||.||||||.. |. ..||.|..|||.....|.. |||.||.|||..|.|||......||||..||| lcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsap NYCYRCGNIASILAFSDADNREPKLFQAVPD |||....|.|..| .... . . ..|..... nYcgeysnkaavlkvdknlklsivqfkpskh |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP2C.PD | 1-122 | 51 | 5.9e-47 | 150.1 | In-house | 142-263 (271) | Show / Hide |
Range on Protein: 1-122 Range on HMM: 142-263/271 Sequence Identity: 51% (63 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP .|.|| | . | | ||..|| |.||.|..|||.||||.. |.|||||||. || ....|| . |.|.|..|||||| |||.. |...||..||| fclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgkdiseefnktngltlvsrahqlvmegynwshdrnvvtifsap NYCYRCGNIASILAFSDADNRE |||||||| |.|| . |. ... nycyrcgnqaailelddelkys |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP5C.PD | 2-129 | 44 | 1.8e-37 | 118.9 | In-house | 216-345 (346) | Show / Hide |
Range on Protein: 2-129 Range on HMM: 216-345/346 Sequence Identity: 44% (57 aa) CFHGNL-KTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP || | .. .|| | .|.||||.. |..|....|.||||.| . | || | ||| ||..|.. |||.|| |.|.. .|||. . |||.||.|||||| vvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqeanGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsap NYCYRCGNIASILAFSDADNR-EPKLFQAV . || .... ..| . . | |.|| nycdqmgnkgafitlrgddlkpkfktfeav |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_3.PD | 1-116 | 41 | 1.3e-34 | 109.7 | In-house | 178-294 (308) | Show / Hide |
Range on Protein: 1-116 Range on HMM: 178-294/308 Sequence Identity: 41% (47 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA .| || . . . . ...| ..|| | .||.|.||. ||.... |.|||| .||.| .||.. .|.|. ||||.|..||... | ||||..|| lcmhGGiseelldlkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsa PNYCYRCGNIASILAFS |.|| . |||..| psycGqldniaavlsvd |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP1C.PD | 1-116 | 40 | 9e-34 | 107.1 | In-house | 141-257 (271) | Show / Hide |
Range on Protein: 1-116 Range on HMM: 141-257/271 Sequence Identity: 40% (47 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA .| || | . . || | | ...|.|| .|||.||||. || .|. . || . || .| ..|.. ..|.||.||||.| .||... ..|||..||| fcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgadvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsa PNYCYRCGNIASILAFS ||| . |...... . pnycgefdnagavmsvd |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_6.PD | 1-116 | 34 | 9.6e-31 | 96.8 | In-house | 142-258 (272) | Show / Hide |
Range on Protein: 1-116 Range on HMM: 142-258/272 Sequence Identity: 34% (40 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE-VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA .| || | . . | .|.. | .. ... ||.|||||. |. || . ||.. || .. ..... .. |..||||.|.||... . ||||..||| lcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGedavkkllekldidlvarahqvvqdGyeffaekklvtifsa PNYCYRCGNIASILAFS .|| . | |... . phycgqfdnaaavmkvd |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_4.PD | 1-117 | 36 | 6.1e-30 | 94.3 | In-house | 141-258 (271) | Show / Hide |
Range on Protein: 1-117 Range on HMM: 141-258/271 Sequence Identity: 36% (43 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA .|.|| | .. | .| | . .| ...| ||.|.||. .| | | ||....|| .| .. ...|| ||||.|..||. . ||.||.|. lcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgvvedvckslevdliirahqvvqdgyevlsgrklitvfsv PNYCYRCGNIASILAFSD |||| | |..| . pnycaqfknaaavlklde |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_5.PD | 1-117 | 29 | 2.5e-24 | 75.6 | In-house | 141-261 (274) | Show / Hide |
Range on Protein: 1-117 Range on HMM: 141-261/274 Sequence Identity: 29% (36 aa) MCFHGNLKTRSVTHDPIRTIDRNMEI--PHKGAFCDLVWSDPEE-VDTWAIS-PRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTV .| || . . . | .... . ..| ||.|.|||. .| .. |. .|| |. .... ...|| |||....|||...||..|||| lcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtv WSAPNYCYRCGNIASILAFSD .||| |. . |..... |. fsapyysgedtnlgavvvvsk |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_2.PD | 1-114 | 36 | 1.2e-23 | 73.4 | In-house | 147-265 (281) | Show / Hide |
Range on Protein: 1-114 Range on HMM: 147-265/281 Sequence Identity: 36% (43 aa) MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVD--TWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHE----GYKYMFDEKLV .| || . . | |.| . .| | |||.|||||. . |..| || . |. | ..| . |.|.|. |||||..| |.|. .. .|| lcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivvekfcadndldlvvrahqlskemirqghklrangrlv TVWSAPNYCYRcGNIASILA ...|| || .| .|.| slfsalnylsm-kndssvlk |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP3C.PD | 1-118 | 32 | 1.7e-22 | 69.8 | In-house | 141-272 (292) | Show / Hide |
Range on Protein: 1-118
Range on HMM: 141-272/292
Sequence Identity: 32% (43 aa)
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEV-------DTW-AISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFD--
.| || | .. . | |...|| |.|..|..|||.|||| | ... |.|| .... | . ||.. |.| | |||. ..||. .
lcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkse
----EKLVTVWSAPNYCYRCGNIASILAFSDA
|.|..|||||. | |..| ...
atgfpslitlfsapnyldvynnkaavlkyenn
|
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| Phosphatase | nvec_231431.AA | Subfamily.PPP7C.PD | 31-127 | 31 | 7.4e-21 | 64.1 | In-house | 238-333 (338) | Show / Hide |
Range on Protein: 31-127 Range on HMM: 238-333/338 Sequence Identity: 31% (30 aa) AFCDLVWSDPEEVD-TWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFsdADNREPKLFQ |..||||.. . .. . ||.| ||| ||..... ||.|. |.|. .|||... ..|..|..|| || | . . . ....|...| qildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvkl--gkdltprivq |
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_7.PD | 1-116 | 29 | 1.4e-17 | 53.6 | In-house | 156-282 (296) | Show / Hide |
Range on Protein: 1-116 Range on HMM: 156-282/296 Sequence Identity: 29% (38 aa) MCFHGNLKTRSVTHDPIRTIDRNM-EIPHKGAFCDLVWSDPEEVDTWAISP----------RGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMF .| || . . . . |. |.| . |. .. ||...|| .|.. |.. || . |. . ... . .||||| |||| . ||.|.. lcvhggispklesledinsierPlaevtedslakdllfadpldvqllaavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffa DEKLVTVWSAPNYCYRCGNIASILAFS |.||.|..|||.| .| ..|... dkkLltifsaprymnesdnsgavlkve |
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| Phosphatase | nvec_231431.AA | PP2Ac | 1-130 | 17 | 3.6e-11 | -25.25 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 1-130
Range on HMM: 1-321/321
Sequence Identity: 17% (56 aa)
MC------------------------------------------------F---HGNL-----K------------------------------------
|. | ..| .
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
-----TRSVT---------------H-----------------------D----------P-------------IRTIDR----NMEIPHKGAFCDLVWS
.|... . . | || ||| |.|..| ||| ||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP---------EEVDTWAISP-RGAGWLFGPKVTQEFVNINNLKLICRAHQLVH----EGYKYMFDE-----KLVTVWSAPNYCYRCGNIASILAF----
|| .|. | ... ||.. |||.|. || . |||.||.||||.| .||....|. ||.|..||||||..|.| |... .
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------SDADNREPKLFQAVP
. . ...|....
VIQYKMDKNLKCHFVQFKPQM
|
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| Phosphatase | nvec_231431.AA | Subfamily.PPP_Nematode_1.PD | 49-127 | 21 | 3.1e-09 | 26.4 | In-house | 189-268 (273) | Show / Hide |
Range on Protein: 49-127 Range on HMM: 189-268/273 Sequence Identity: 21% (17 aa) SPRGAGWLFGP-KVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQ || . ... |. .| . ..... |....|.|||.. ....|.|..||... | .|... ..||.. sPvtendidekskivkellkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| nvec_231431.AA | Protein | None | 146 | None | Fasta, JSON |
| nvec_231431.NA | RNA | None | 438 | None | Fasta, JSON |
| nvec_231431.AA.PD_1-130 | Protein Phosphatase Domain | None | 130 | None | Fasta, JSON |