Gene SDP1
SDP1
Species: S.cerevisiae
Alias: SDP1
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of SDP1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | SDP1.AA | Family.DSP.PD | 48-196 | 23 | 1.4e-22 | 71.5 | In-house | 103-249 (387) | Show / Hide |
Range on Protein: 48-196 Range on HMM: 103-249/387 Sequence Identity: 23% (35 aa) SSLDVRRIYPkgpllvlpeKIYLYSEPTVKELLPF-----DVVINVAEEaNDLRMQVPAVEYHHYRWEHDSQIALDL--PSLTSIIHAATTKREKILIHC ....|.| ..|| | ..|.| .. ...|.... .. .. ..|... ... .. |.. . .|. . .....|.||. | engkpseilp---------hlylgsllaaknlewlkelgvtkivnltdd-kpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHC QCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRAD-KINPSIGLIFQLMEWEVALNA ..||.||||||.||...|.| ..|...|. |.|. | . ||...| . kaGkgRsgtliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklk |
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| Phosphatase | SDP1.AA | DSPc | 68-193 | 32 | 1.6e-54 | 191.5 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 68-193 Range on HMM: 1-151/151 Sequence Identity: 32% (49 aa) IYLYSEPTVK------ELLPFDVVINVAEEAN---------DLRMQVPAVEYH----HYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSA .||.|.|... . . ...|||...| . ..|..|.|..| |..|.|...|. ..|..|..|.....| .|.|.|||.|.|||| LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA TLIIAYIMKYHNLSLRHSYDLL-----KSRA-DKINPSIGLIFQLMEWEVA .|.|||.|||.|.|... ||.. |.|. ..|.|......||.|.|. CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | SDP1.AA | DSPc | 59-193 | 30 | 4.9e-54 | 186.76 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 59-193 Range on HMM: 1-172/172 Sequence Identity: 30% (53 aa) GPLLVLPEKIYLYSEPTVK-------ELLPFDVVINVAEEAN-----------------------DLRMQVPAVEY--HHYRWEHDSQIALDLPSLTSII || ..|. .||.|.|. . .....||||..| . ..|..|... .|.||.| ..|. ..|... .| GPSEITPH-LYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFI HAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLL-----KSRA-DKINPSIGLIFQLMEWEVA |....|. |.|.|||.|.||||||.|||.|||.|.|....|... |.|. ..|.|......||.||| HDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | SDP1.AA | Subfamily.DSP14.PD | 82-191 | 33 | 1.7e-22 | 70.9 | In-house | 27-136 (138) | Show / Hide |
Range on Protein: 82-191 Range on HMM: 27-136/138 Sequence Identity: 33% (37 aa) FDVVINVAEEANDLRMQvpAVEYHHYRWE--HDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINP . ...||. |. . ... |.. . . | .....| . . |.....| |.|.|| | ||||.|..||.|||..||||..| |.||. |.| itlivnvttelpetkle--dvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmkyeklsLreayklvksaRpiirP SIGLIFQLMEWE | ||...| nvGFwkqlidyE |
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| Phosphatase | SDP1.AA | Subfamily.DSP6.PD | 83-191 | 32 | 7.2e-22 | 68.6 | In-house | 29-139 (141) | Show / Hide |
Range on Protein: 83-191 Range on HMM: 29-139/141 Sequence Identity: 32% (35 aa) DVVINVAEEANDLRMQVPAVEYHHYRWE--HDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPS |.||... .. . . ..|.. | . ..| .| . | | .| .|.|.|| |.||| |...||.||...||| ..|||.|.. .| | kyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlaylmkklalslndaydlvkkkksnisPn IGLIFQLMEWE .. ||...| fnfmgqlldfe |
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| Phosphatase | SDP1.AA | Subfamily.DSP10.PD | 82-191 | 28 | 8.3e-22 | 68.6 | In-house | 28-139 (141) | Show / Hide |
Range on Protein: 82-191 Range on HMM: 28-139/141 Sequence Identity: 28% (32 aa) FDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQI--ALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINP ..|.||. .. . .|.|.. . ... . |. | . ...|.||. |.|||||..|||.||. .|||...| ..|.. | | ikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrPiisP SIGLIFQLMEWE .... ||.|.| nlnfmGqllefe |
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| Phosphatase | SDP1.AA | Subfamily.DSP1.PD | 84-191 | 28 | 1e-21 | 68.4 | In-house | 30-137 (139) | Show / Hide |
Range on Protein: 84-191 Range on HMM: 30-137/139 Sequence Identity: 28% (30 aa) VVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGL ..||..| .. .. . . .....| . |.....|. ..|.||| |.|||||...||.|| ....|..... .|.||.| .|.. || allnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrrsiisPnfgf IFQLMEWE .|.| vgqLlefe |
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| Phosphatase | SDP1.AA | Subfamily.DSP8.PD | 83-193 | 27 | 2.3e-21 | 67.3 | In-house | 29-141 (143) | Show / Hide |
Range on Protein: 83-193 Range on HMM: 29-141/143 Sequence Identity: 27% (31 aa) DVVINVAEEANDLRMQVPAVEYHHY--RWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPS ..|.|..|. . .. ..... . ... .. ... .. | | .. |.|.|| | |||||..||||||. ..|| ..| .|.. |.|. syvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiayimktlemsldeayrfvkekrptispn IGLIFQLMEWEVA . . ||.|.| lnflgqLleyeke |
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| Phosphatase | SDP1.AA | Subfamily.DSP12.PD | 115-191 | 35 | 4.1e-21 | 66.5 | In-house | 63-139 (143) | Show / Hide |
Range on Protein: 115-191 Range on HMM: 63-139/143 Sequence Identity: 35% (27 aa) IALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE . |.. .. |. . |....|.||. |.|||.|..|||.||...|||.. ..|.|. .|.| | . || .| lLshldeavrFieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkkeiepNegFleQLklfe |
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| Phosphatase | SDP1.AA | Subfamily.STYXL1.PD | 60-191 | 28 | 2.3e-20 | 64.2 | In-house | 2-141 (143) | Show / Hide |
Range on Protein: 60-191 Range on HMM: 2-141/143 Sequence Identity: 28% (40 aa) PLLVLPEKIYLY-----SEPTVKELLPFDVVINVAEEANDLRMQVPA-VEYHHYRWEHDS--QIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLI | |||.|.|| .|..|. | ..||. .|..| .. .. | . | .. .. | . . |. .. | .|. .|.||||..|| PvevlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaavi IAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE ||.| .....|...|. || . ..| ... || ||| iaylmyskkitlkkaykylkkckenvkPnrafveqlseWe |
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| Phosphatase | SDP1.AA | Subfamily.DSP19.PD | 110-191 | 34 | 1.7e-18 | 57.8 | In-house | 56-137 (139) | Show / Hide |
Range on Protein: 110-191 Range on HMM: 56-137/139 Sequence Identity: 34% (28 aa) EHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE . . .. |.. . |. | .| .|.||. | ||||...|||.|| ..|||..... ... |.| | | || |.| lpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpcikPneGFikqLkeye |
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| Phosphatase | SDP1.AA | Subfamily.Slingshot.PD | 83-191 | 30 | 1.7e-17 | 54.5 | In-house | 29-137 (139) | Show / Hide |
Range on Protein: 83-191 Range on HMM: 29-137/139 Sequence Identity: 30% (34 aa) DVVINVAEEANDLRMQvpAVEYHHYRW--EHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPS . ..||..| .. . ..|.. | |..... . . |..| .| |.|.||. |.||||. .||| || ..||| .... .|.| . |.| eyilnvtkeidnffpe--kfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerrsiikpn IGLIFQLMEWE |.. || ..| kgflkqlkvye |
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| Phosphatase | SDP1.AA | Subfamily.LRR-DSP.PD | 131-191 | 41 | 3.8e-17 | 53.4 | In-house | 75-135 (137) | Show / Hide |
Range on Protein: 131-191 Range on HMM: 75-135/137 Sequence Identity: 41% (25 aa) TKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE .. .||||. |.||||||.|||.||...| .....|| ... .|.| .|.. || .| rekggvlihcragvsrsatlviaylmkknslkfkealdlvikkrpriypnrgfldqlkkfe |
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| Phosphatase | SDP1.AA | Subfamily.DSP3.PD | 126-191 | 36 | 3.6e-16 | 50.4 | In-house | 82-146 (148) | Show / Hide |
Range on Protein: 126-191 Range on HMM: 82-146/148 Sequence Identity: 36% (24 aa) IHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRAdKINPSIGLIFQLMEWE .| ..|. |.|.||. |.||||||..||.| ...|.|... ... .| | |.. ||.| . dealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkr-eilPneGflkqLleld |
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| Phosphatase | SDP1.AA | Subfamily.DSP15.PD | 122-191 | 37 | 3.7e-15 | 47.1 | In-house | 67-136 (138) | Show / Hide |
Range on Protein: 122-191 Range on HMM: 67-136/138 Sequence Identity: 37% (25 aa) LTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWE ||.. . ...|.|| |.||| ||..|||| .|| ... .|. || .|. ||.|.| sidfihkcrleggnvlvhclaGisrsvtlvvayimtvtelswedalkavkaarsvanPnvGfrrqlqefe |
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| Phosphatase | SDP1.AA | Subfamily.STYX.PD | 118-192 | 39 | 6.2e-15 | 46.3 | In-house | 71-145 (146) | Show / Hide |
Range on Protein: 118-192 Range on HMM: 71-145/146 Sequence Identity: 39% (29 aa) DLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEV || ..| . .| |.|.| ..|.||||.|.|||||. . | |... .. | ||| |.. ||.|.|. ylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyea |
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| Phosphatase | SDP1.AA | Subfamily.PTPMT1.PD | 124-177 | 33 | 1.9e-11 | 35.0 | In-house | 77-130 (146) | Show / Hide |
Range on Protein: 124-177 Range on HMM: 77-130/146 Sequence Identity: 33% (18 aa) SIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKI ..|. ..|.... .||. | .|||||...|.|| ..|| .. ..||.. ..| efiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqi |
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| Phosphatase | SDP1.AA | Subfamily.CDC14.PD | 124-163 | 28 | 2.3e-08 | 25.0 | In-house | 189-228 (258) | Show / Hide |
Range on Protein: 124-163 Range on HMM: 189-228/258 Sequence Identity: 28% (11 aa) SIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSL . .... . . .| .||. || | .||| .|..|..... kfleitekaeGaiavhCkaGLGrtgtligcylikhyrfta |
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| Phosphatase | SDP1.AA | Subfamily.R_Nematode_3.PD | 104-180 | 23 | 9.9e-08 | 22.6 | In-house | 169-252 (267) | Show / Hide |
Range on Protein: 104-180 Range on HMM: 169-252/267 Sequence Identity: 23% (19 aa) YHHYR-WEhDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLII---AYIMKYHNL---SLR-HSYDLLKSRADKINPS ..|. |. .... . .....|... . . ...|| | |||||| .| . .. .|. ..| |.|| |. hllykgWk-elnapeepkealelikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqte |
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| Phosphatase | SDP1.AA | Subfamily.DSP23.PD | 85-162 | 24 | 1.2e-07 | 22.8 | In-house | 17-95 (128) | Show / Hide |
Range on Protein: 85-162 Range on HMM: 17-95/128 Sequence Identity: 24% (19 aa) VINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDL-PSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLS ......|.. .|.. .. . . ||. | |.. | | | . .|| || |. ||. |..| ..|. lvslttegapyseaapsltlrridipdfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeegla |
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| Phosphatase | SDP1.AA | Subfamily.PTPDC1.PD | 121-174 | 25 | 1.1e-06 | 19.2 | In-house | 155-208 (229) | Show / Hide |
Range on Protein: 121-174 Range on HMM: 155-208/229 Sequence Identity: 25% (14 aa) SLTSIIHAATtKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSR-A . .. | . || .|| || | || .|.. ..|. .. .|..|. . divkvvdfal-eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp |
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| Phosphatase | SDP1.AA | Subfamily.N_Nematode_5.PD | 104-156 | 15 | 1.5e-06 | 18.5 | In-house | 157-213 (258) | Show / Hide |
Range on Protein: 104-156 Range on HMM: 157-213/258 Sequence Identity: 15% (9 aa) YHHYRWEHDSQIALDLPSLTSIIHAATTK----REKILIHCQCGLSRSATLIIAYIM ||. |..... . . .. |. . | ........ || |..|.... .. yhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsva |
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| Phosphatase | SDP1.AA | Subfamily.N_Nematode_4.PD | 87-154 | 24 | 2.4e-06 | 18.1 | In-house | 148-217 (264) | Show / Hide |
Range on Protein: 87-154 Range on HMM: 148-217/264 Sequence Identity: 24% (17 aa) NVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATT--KREKILIHCQCGLSRSATLIIAY . |. | . |.. .. | .| || .. .. | | . | .|| |. |.|||. . tntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekPivvhcsaGvGrtatlvGid |
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| Phosphatase | SDP1.AA | Subfamily.N_Nematode_1.PD | 103-157 | 27 | 4.1e-06 | 17.2 | In-house | 167-221 (265) | Show / Hide |
Range on Protein: 103-157 Range on HMM: 167-221/265 Sequence Identity: 27% (15 aa) EYHHYRWEHDSQIALDLPSLtSIIHAATTKREKILIHCQCGLSRSATLI-IAYIMK .|. | . || .| ...|. .... |..|| |. |. |.. |.||. hyqWtdWPdrGvPpadlaal-elleavrgskgPivvhCsaGiGrtGtivaieyild |
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| Phosphatase | SDP1.AA | Subfamily.Laforin.PD | 118-169 | 26 | 5.1e-06 | 17.2 | In-house | 89-141 (165) | Show / Hide |
Range on Protein: 118-169 Range on HMM: 89-141/165 Sequence Identity: 26% (14 aa) DLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHS-YDL || ..|| | .. .||..|. ||.... ... . ||.. | | nlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfl |
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| Phosphatase | SDP1.AA | Subfamily.PTEN.PD | 133-161 | 30 | 6.2e-06 | 16.7 | In-house | 94-122 (305) | Show / Hide |
Range on Protein: 133-161 Range on HMM: 94-122/305 Sequence Identity: 30% (8 aa) REKILIHCQCGLSRSATLIIAYIMKYHNL .. . .||. | |. ..| ||..|. snVvavHCkaGkGRtGvmicayLlksgik |
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