OCA2
Species: S.cerevisiae
Alias: OCA2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: OCA
Subfamily: OCA
Protein domain

Protein domains of OCA2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase OCA2.AA Y_phosphatase2 3-169 41 2.3e-97 332.67 Pfam 1-184 (184) Show / Hide
Range on Protein: 3-169
Range on HMM: 1-184/184
Sequence Identity: 41% (77 aa)

YIPPLNFSPVVSTDVSLYRSGYPMPLNYSFIKHQLHLKTIIYIGDKDRPLEEYQS-FLESEKIKYYHIFMDSSRD--------------EGIQERMNQVL
..||||||.|..|||..|||.||.|.|..|..|||||||||.......|...... |.||..||||||.|....|              ......|...|
VVPPLNFSHVEPTDVYIYRSSYPRPNNFPFLRHQLHLKTIIWLCPEPYPQDNLCEKFCESHHIKYYHIHMEGNKDPDNDCPKIKKNPWVNIPDHCMRRCL

HLVLDVRNYPILVHSNKGKHRVGVVVGIIRKLLQGWSTAGICQEYGLFSGG-MKDGVDLEFITMFETNLKIPRNV-IPGFAKHC
...|...|||...|.|.||||.|.|.|..||.||.|.||.||.||..||.. .....| |||.||.||....... ......||
QTLLNKDNYPCYIHCNRGKHRTGCVIGCLRKKLQNWNTASICNEYRRFSHPRKRRIHDEEFIEMFDTNIEVHDHNKKWKWCWHC

Phosphatase OCA2.AA Family.OCA.PD 3-168 45 3.7e-65 207.2 In-house 1-164 (165) Show / Hide
Range on Protein: 3-168
Range on HMM: 1-164/165
Sequence Identity: 45% (77 aa)

YIPPLNFSPVvstDVSLYRSGYPMPLNYSFIkHQLHLKTIIYIGDKDRPLEEYQSFLESEKIKYYHIFMD---SSRDEGIQERMNQVLHLVLDVRNYPIL
.|||||||.|   ...||||.||..||.||. ..|.|||||.......| |....|.|.|.||..|| .|   ....|  .|....||...|||.|||.|
lipplnFstv---eeelyrssypnelnfsfl-ktLkLktiislspeelpqesllkfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypvl

VHSNKGKHRVGVVVGIIRKlLQGWSTAGICQEYGLFSGGMKDGVDLEFITMFETNLKIPRNVIPGFAKH
.|.||||||.|.|||..|| ||.|..| |..|| .|||.... .. |||..|.|.|.. .|..| ..|.
ihcnkGkhrtglvvgclRk-lqkWnlasileEyrrFsgskirileeefielfdteleveknkkpkwlka

Phosphatase OCA2.AA Subfamily.OCA.PD 3-168 45 3.7e-65 207.2 In-house 1-164 (165) Show / Hide
Range on Protein: 3-168
Range on HMM: 1-164/165
Sequence Identity: 45% (77 aa)

YIPPLNFSPVvstDVSLYRSGYPMPLNYSFIkHQLHLKTIIYIGDKDRPLEEYQSFLESEKIKYYHIFMD---SSRDEGIQERMNQVLHLVLDVRNYPIL
.|||||||.|   ...||||.||..||.||. ..|.|||||.......| |....|.|.|.||..|| .|   ....|  .|....||...|||.|||.|
lipplnFstv---eeelyrssypnelnfsfl-ktLkLktiislspeelpqesllkfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypvl

VHSNKGKHRVGVVVGIIRKlLQGWSTAGICQEYGLFSGGMKDGVDLEFITMFETNLKIPRNVIPGFAKH
.|.||||||.|.|||..|| ||.|..| |..|| .|||.... .. |||..|.|.|.. .|..| ..|.
ihcnkGkhrtglvvgclRk-lqkWnlasileEyrrFsgskirileeefielfdteleveknkkpkwlka

Phosphatase OCA2.AA Family.DSP.PD 37-115 19 1.4e-06 16.5 In-house 131-205 (387) Show / Hide
Range on Protein: 37-115
Range on HMM: 131-205/387
Sequence Identity: 19% (16 aa)

LHLKTIIYIGdKDRPLEEYqsfleSEKIKYYHIFMDSSRDEGIQERMNQVLHLVLD--VRNYPILVHSNKGKHRVGVVVGI
|  . |. .  .|.| ...     ...|||..|..| .  . ... . ...  . .  . .  .||| . || | |... .
lgvtkivnlt-ddkpqftk-----elgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliia

Sequence
Name Sequence Type Origin Length Description Download
OCA2.AA Protein None 197 None Fasta, JSON
OCA2.NA RNA None 591 None Fasta, JSON
OCA2.AA.PD_3-169 Protein Phosphatase Domain None 167 None Fasta, JSON