OCA1
Species: S.cerevisiae
Alias: OCA1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: OCA
Subfamily: OCA
Protein domain

Protein domains of OCA1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase OCA1.AA Family.DSP.PD 59-190 20 4.3e-07 18.5 In-house 102-215 (387) Show / Hide
Range on Protein: 59-190
Range on HMM: 102-215/387
Sequence Identity: 20% (28 aa)

VSHAPQERIVPplnfcpverYLYRSGQPSPVNFPFLLNLKLKTIIWLSNEEPQDTLlefcdthriNLQFAAINPdaGEDDNPWDGLTEHsIINVLQTIVT
| . .  .| |          ||  .     |.. | .|. . |. |. ..|| |          .|... ..   . ||..   | .. ......| . 
vengkpseilp---------hlylgsllaaknlewlkelgvtkivnltddkpqftk---------elgikylri--pidDhnapplenl-fekaidfiee

--QENYPLLVCCGMGRHRTGTVIGCLRRIM-GWNL
 ...   || | .|. |.||.| . .    |..| 
gndskgvVlVHCkaGkgRsgtliiaYlmksegltl

Phosphatase OCA1.AA Y_phosphatase2 67-236 45 3.1e-99 339.03 Pfam 1-184 (184) Show / Hide
Range on Protein: 67-236
Range on HMM: 1-184/184
Sequence Identity: 45% (83 aa)

IVPPLNFCPVER---YLYRSGQPSPVNFPFLLN-LKLKTIIWLSNE-EPQDTLLE-FCDTHRINLQFAAINPDAGEDD-------NPWDGLTEHSIINVL
.||||||..||.   |.|||..|.|.||||| . |.|||||||..| .|||.|.| ||..|.|.............|.       |||.....|.....|
VVPPLNFSHVEPTDVYIYRSSYPRPNNFPFLRHQLHLKTIIWLCPEPYPQDNLCEKFCESHHIKYYHIHMEGNKDPDNDCPKIKKNPWVNIPDHCMRRCL

QTIVTQENYPLLVCCGMGRHRTGTVIGCLR-RIMGWNLASVSEEYRRFTGSRGGRILVELLIEAFDTNLVKIDKNKAPSWLLTA
||.....|||....|..|.||||.|||||| ....||.||...|||||...|..||..| .||.||||....|.||...|....
QTLLNKDNYPCYIHCNRGKHRTGCVIGCLRKKLQNWNTASICNEYRRFSHPRKRRIHDEEFIEMFDTNIEVHDHNKKWKWCWHC

Phosphatase OCA1.AA Family.OCA.PD 67-235 47 4.7e-68 217.1 In-house 1-164 (165) Show / Hide
Range on Protein: 67-235
Range on HMM: 1-164/165
Sequence Identity: 47% (80 aa)

IVPPLNFCPVERYLYRSGQPSPVNFPFLLNLKLKTIIWLSNEE-PQDTLLEFCDTHRINLQFAAINpdagEDDNPWDGLTEHSIINVLQTIVTQENYPLL
..|||||..||..||||..|...||.|| .|||||||.||.|| ||..||.|.....|.|......    ....... ..|.....||.......|||.|
lipplnFstveeelyrssypnelnfsflktLkLktiislspeelpqesllkfveeeniklihikvd----kkkkdlveieeellkrvlkilldvdnypvl

VCCGMGRHRTGTVIGCLRRIMGWNLASVSEEYRRFTGSRgGRILVELLIEAFDTNLVKIDkNKAPSWLLT
..| .|.||||.|.||||....|||||. ||||||.||.  ||| | .||.|||.|.. . ||.|.||..
ihcnkGkhrtglvvgclRklqkWnlasileEyrrFsgsk-irileeefielfdtelevek-nkkpkwlka

Phosphatase OCA1.AA Subfamily.OCA.PD 67-235 47 4.7e-68 217.1 In-house 1-164 (165) Show / Hide
Range on Protein: 67-235
Range on HMM: 1-164/165
Sequence Identity: 47% (80 aa)

IVPPLNFCPVERYLYRSGQPSPVNFPFLLNLKLKTIIWLSNEE-PQDTLLEFCDTHRINLQFAAINpdagEDDNPWDGLTEHSIINVLQTIVTQENYPLL
..|||||..||..||||..|...||.|| .|||||||.||.|| ||..||.|.....|.|......    ....... ..|.....||.......|||.|
lipplnFstveeelyrssypnelnfsflktLkLktiislspeelpqesllkfveeeniklihikvd----kkkkdlveieeellkrvlkilldvdnypvl

VCCGMGRHRTGTVIGCLRRIMGWNLASVSEEYRRFTGSRgGRILVELLIEAFDTNLVKIDkNKAPSWLLT
..| .|.||||.|.||||....|||||. ||||||.||.  ||| | .||.|||.|.. . ||.|.||..
ihcnkGkhrtglvvgclRklqkWnlasileEyrrFsgsk-irileeefielfdtelevek-nkkpkwlka

Sequence
Name Sequence Type Origin Length Description Download
OCA1.AA Protein None 238 None Fasta, JSON
OCA1.NA RNA None 714 None Fasta, JSON
OCA1.AA.PD_67-236 Protein Phosphatase Domain None 170 None Fasta, JSON