Gene CYR1
CYR1
Species: S.cerevisiae
Alias: CYR1
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of CYR1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Ad_cyc_g-alpha | CYR1.AA | Ad_cyc_g-alpha | 367-420 | 33 | 1.1e-18 | 69.26 | SMART | 1-57 (57) | Show / Hide |
Range on Protein: 367-420 Range on HMM: 1-57/57 Sequence Identity: 33% (19 aa) REATTPTIET--PISCKPSLFRLDTNLEDVTDI-TKTVPPTAVNSTLNSTHGTETAS .|...||... |..|......|||||.|...| ||..|.|........||..|... DEHIGPTDRQMDPSMCPGNMWHLDTNLNDMEGILTKPPPLTPMDCSFINTHEPEKHH |
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| RA | CYR1.AA | RA | 676-753 | 17 | 2.1e-16 | 59.02 | Pfam | 1-96 (96) | Show / Hide |
Range on Protein: 676-753 Range on HMM: 1-96/96 Sequence Identity: 17% (17 aa) RHYAIRIFNTDDT----FTTLSCTPATTVEEIIPALKRKFNI--TAQGNFQI---SLKVGKLSK-ILRPTSKPILIE--------RKLLLLNGYRK ... ||....|.. ..|..... ||..|.| .. |||.| . ...... .| . . .| .. .| .| . ..| ... DCHCIRVYMDDGCQGCTYKTIRVPKNTTAQEVIRQALRKFHIDEDDPDDYCLWEEFLCRHGEERRVLPDHECPLQIQMQWPRDECMRRFYLRRRED |
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| Ad_cyc_g-alpha | CYR1.AA | Ad_cyc_g-alpha | 367-420 | 28 | 1.2e-15 | 57.05 | Pfam | 1-56 (56) | Show / Hide |
Range on Protein: 367-420 Range on HMM: 1-56/56 Sequence Identity: 28% (16 aa) REATTPTIETPIS-CKPSLFRLDTNLEDVTDI-TKTVPPTAVNSTLNSTHGTETAS .|...|| ....| .... ..|||||.....| ||. |||....... ....|. DETIGPTDRHTRSMEEGGMWHLDTNLNHMEGIITKPPPPTPMDNSFINDGESEKHE |
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| Phosphatase | CYR1.AA | Group.PPM.PD | 1341-1833 | 46 | 1.1e-150 | 492.1 | In-house | 23-459 (459) | Show / Hide |
Range on Protein: 1341-1833
Range on HMM: 23-459/459
Sequence Identity: 46% (213 aa)
NVNFRLRTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDdeCLLCLHDSKNqnadyGHNISRIVRDIYDKILIRQLERYGDETD-----------
... .|...|. .||.|||||.. |.|... | |..|.|. || ......| . |......... . ||| .||... ||.....|.||| .|
saehhlessagsgnglrygvasmqgwrkemEDrhvivenfdnnd--sffgVfDGHg-----GaeaaefaakkLpkilkkqlkkkkdevskksaeasldnd
---DNIKTALRFSFLQLNKEINGMLNSVDngadvanlsYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNnGDYQTLTKQHLPTKREEYERIRISGG
|.|..... . |. . ... ||....|..|.||||. ||.||..|.|..| |....|.|.| |...||.|||. .||.|.. |...|...|
drgekvkkalrsafleldedlseeaneke---------epgkdsGtTAvvalingkklyvANaGDSravLcrn-gkavplskdHkpenpeEreRIekagG
YVNN-GKLDGVVDVSRAVGFFDLLPH---IHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENSTDplraaaelkdhamaygctenitilcl
|||.|..|| . ..|.||.|||.||..||.|..|...||.... ..|....||........|.|.. .. ....... |.. |
sveidgRvnGilavsRalGdhdlkkeeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlek--------------------------
alyeniqqqNRFTLNKNSLMTRRSTFEDTtLRRlqpeispptGnlamvftdiksSTfLWELFPNAMRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAF
|| ....... . . . |.||.|||||.|....||..|..|||||..|..||||..|||||||||||..|||||||||.|||||||.||||||||
---------kkkelkkdleeiaerlvdea-lak---------g-----------st-gdgtscDNiTvivvtlndamrrqleivkkeevleeelafmvae
PTPTSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSE
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lteksgltallsvqlklldaqaeeeitsvqdglqvtdrngeiiyqglsvrmgihwgcpvpeldlvtqrmdylgpmvnkaarvqgvadggqiamssdfyse
FNKIMKYHERV
fnkimkyherv
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| RA | CYR1.AA | RA | 676-756 | 15 | 6e-14 | 53.59 | SMART | 1-102 (102) | Show / Hide |
Range on Protein: 676-756 Range on HMM: 1-102/102 Sequence Identity: 15% (16 aa) RHYAIRIFNTD-------DTFTTLSCTPATTVEEIIPALKRKFNITA--QGNFQISLKV---GKLSKILRPTSKPILIER---------KLLLLNGYRKS ... .|....| .|..|. .|. ||....| .| .||.... . ... ... ||. ... .. ...... . ..|| HTHVLRVYMDDPKYNNCGQTYKTIRVTKRTTAQDVIQQLLEKFHLDDEDWEEYCLVECHPHHGKERVLPPHECPLQIMKNWPRDMMSPRQHMYRFVLRKR DP |. DD |
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| Phosphatase | CYR1.AA | Family.PPM.PD | 1346-1833 | 63 | 1.4e-232 | 762.3 | In-house | 5-495 (495) | Show / Hide |
Range on Protein: 1346-1833
Range on HMM: 5-495/495
Sequence Identity: 63% (315 aa)
LRTTASIINGMRYGVADTLGQRDYVssRDVT--FERFRGNDDECLLCLHDSKNqnadyGHNISRIVRDIYDKILIRQLERYGDETD--------DNIKTA
||.||..||.|||||.. |.|... .|.. .|....|.| .|....|. . |......... ..|||..|||...||.....|.|||..||.|.
arteasssnglrygvasmqgwrsem--eDahvvvenlennedfslfgvfDGhg-----Gaeaaefaakklhkilkkqlekkddeksstsaessaekvkea
LRFSFLQLNKEINGMLNSVDngadvanlsyADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNnGDYQTLTKQHLPTKREEYERIRISGGYVNN--GKL
.|.. .||... |. ||....|..||||||..||.||..|.|..| |....|.|.| |...||.|||..||.|.. |...||..||||.
lrkafleldeelseelneks----------agkdsGtTAvvvlirgkklyvAnaGDsravLcrn-gkavelskdHkpenpeEreRIekagGkvvirdgrv
DGVVDVSRAVGFFDLLP----HIHASPDISVVTLT-KADEMLIVATHKLWEYMDVDTVCDIARENS----TDPLRAAAELKDHAMAYGCTENITILCLAL
|.||| . ...|.|||..|.|| ..||.|..|...||.... ..|....||.. .|. ..|.||.|.|.|.|...|||.|..||||||.|||||
nGvlavsRalGdfdlkkeeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvval
YENIQQQNRFTLNKNSLMTRRSTFEDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLWELFPNAMRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPT
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yenikqqnrfvlnknslmtrrstfedttlrrlqeeispptgnlamvftdiksstflwelfpnamrtaikthndimrrqlriyggyevktegdafmvafpt
PTSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEFN
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ptsgltwclsvqlklldaqwpeeitsvqdgcqvtdrngniiyqglsvrmgihwgcpvpeldlvtqrmdylgpmvnkaarvqgvadggqiamssdfysefn
KIMKYHERV
kimkyherv
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| Phosphatase | CYR1.AA | PP2C | 1373-1617 | 27 | 3.5e-86 | 297.42 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 1373-1617
Range on HMM: 1-284/284
Sequence Identity: 27% (79 aa)
RDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLERYGDETDD---NIKTALRFSFLQLN--KEINGMLNSVDN--GADVANL--
|. | |..| .... ..|. .| |. .....|... ..|.....|...| ... . | . ..| ||...| .. ... .| . .... ..
WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP
-------SYADLLSGACSTVIYIRGKK--LFAANLGDCMAILSKNNGDY---QTLTKQHLPTKREEYERIRISGGYVN---NGKLDGV-VDVSRAVGFFD
..... ||.. ...|||..| |. ||.||..|.|..|.... ..||..| |. ..|..||| .||.|. .... || ..|||| |.|.
WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFH
LLP---------HIHASPDIS-VVTLTKA-DEMLIVATHKLWEYMDVDTVCDIARENSTD---PLRAAAELKDHAMAYGCTENI
..| ...|.|||. ....|. ||.|| |.. ||..|. ..||||.|.. .| |..|. .|.|...|||...||
YKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI
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| Phosphatase | CYR1.AA | CYCc | 1611-1833 | 21 | 4.3e-71 | 243.41 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1611-1833 Range on HMM: 1-231/231 Sequence Identity: 21% (54 aa) YGCTENITILCLALYENIQQQNRFTLNKNSLMTRRSTFEDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLW-ELFPNAMRTAIKTHNDIMRRQLRIYG-- . .| ..|| | .....|.. . .|...|.... ...||||...| |. . .| ........|.. ..|... .| MEKQKNDRLLCQMLPRHVANQLKQGR--------------------HPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCY ---GYEVKTEGDAFMVAFPTPTSGLT--------------WCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVT-Q .|.|.|.|||.||....||. .. || ..|. . |.|. ..... ....| ...|......|..|.|||.|..| . . .. HNYCYKVETIGDAYMVVSGCPTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMP RMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEF-------NKIMKYHERV |..| |..|| |.|.. ..|.||| .|...|.. .. ..... . RYCYFGDTVNMASRMESTGDPGQIHVSEETYWCLCLDQFERRRCGQFEFEP |
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| Phosphatase | CYR1.AA | PP2Cc | 1347-1622 | 20 | 3.1e-52 | 180.77 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 1347-1622 Range on HMM: 1-338/338 Sequence Identity: 20% (77 aa) RTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLERYGDE------------------- . . .|.|||.... | .. .|. . |. . .. | || .....|. ..|...|. |. HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP-------FFGVFDG-----HGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMW ---TDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANLSYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNNG---------DYQTLTKQHLPTKR ...... ||| .||....|| .. .|..|||.||. ||.||..|.|..|.. ||. | | HDKWFEDWEDALRKAFLRMDEEI------------------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNE EEYERIRISGG--------YVNNG-----KLDGV---VDVSRAVGFFDLL------------------------PHIHASPDISVVTL------TKADEM .|..||. .|| .| |. ...|| |||| | ... |.. | ||.....| |. |.. DERRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDF LIVATHKLWEYMDVDTVCDIARENS--------------------------TDPLRAAAELKDHAMAYGCTENITILCL || .. ||..|. ..|.||.|.. || .|| .| | | |.|.... LILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV |
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| Phosphatase | CYR1.AA | Subfamily.LRR-PP2C.PD | 1357-1622 | 25 | 1e-32 | 103.3 | In-house | 11-255 (257) | Show / Hide |
Range on Protein: 1357-1622
Range on HMM: 11-255/257
Sequence Identity: 25% (67 aa)
RYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNqnadyGHNISRIVRDIYDKILIRQLERYGDetddNIKTALRFSFLQLNKEIngmlnsvdn
. | .|..|.| . . | . ||...|| ...| | |.. ... . ||| |. . | . .|. .. ... |
kvgfsdmiGrrptmedelviyGsfrdksdedyyalfdGhg-----Graaakfaseelykilaelldlnna----nPlkslkkaykeistqi---------
gadvanlSYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVNNG----KLDGVVDVSRAVGFFDLLPHI
| |. .....| ..| . ||.|| ..|....| . |. | |.. .| .||. || |.. ...| . ||||.| | |..
-------serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsflePfv
HASPDIS-VVTLTKADEMLIVATHKLWEYMDVDTVCDIAReNSTDPLRAAAELKDHAMAYGCTENITILCL
. ||.| .. .| |. ||.| .|. . . ..|. ...|| .|| .|.|.|| |.||... .
vpdPdlsqsleiskkdkflilacdGiwdlisdeeaveiva-gisdpekaaeklrdlayssGstdnisvivi
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| Phosphatase | CYR1.AA | Subfamily.PPM1A.PD | 1354-1626 | 24 | 4.5e-30 | 94.7 | In-house | 8-280 (309) | Show / Hide |
Range on Protein: 1354-1626
Range on HMM: 8-280/309
Sequence Identity: 24% (71 aa)
NGMRYGVADTLGQRDYVSSRDVTFERFRG-NDDECLLCLHDSKNqnadyGHNISRIVRDIYDKILIRQ---LERYGDETDDNIKTALRFSFLQLNKEINg
||.|||.. | | . .. .. . .| . . | |...|.. . ...... . ... ...| |||.||.| ..|.
nglryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHa-----GskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekir-
MLNSVDNGADVanlsyadllSGACSTVIYIRGKKLFAANLGDCMAILSKNnGDYQTLTKQHLPTKREEYERIRISGGYVNNGKLDGVVDVSRAVGFFDLL
|.....|.| ||. ..|. .. |||. ||.|| |.||.| | . |. | |.. .| |||. ||| .....| . ||||.| .|
klvelskgedk---------sGsTavvvlvspkklylancGDsRavlsrn-gkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydyk
P---------HIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIAREN---STDPLRAAAELKDHAMAYGCTENITILCLALYE
. ..|.. |.. .. || |..|. .|. |. ..|... ... ..|. ..|.|||... | ..|.... ..| .
ekpekkateqlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvllpg
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| Phosphatase | CYR1.AA | Subfamily.PHLPP.PD | 1484-1621 | 33 | 1.6e-24 | 76.3 | In-house | 119-256 (257) | Show / Hide |
Range on Protein: 1484-1621 Range on HMM: 119-256/257 Sequence Identity: 33% (46 aa) LFAANLGDCMAILSKnNGDYQTLTKQHL-PTKREEYERIRISGGYVN-NGKLDGVVDVSRAVGFFDLLPHIHASPDISVVTLTKADEMLIVATHKLWEYM | ||| |.| ..| . || |.| . . ||..||. .... ..|..||. .| .|.. | | . .| .. |.||. ||.||. ..||| . ltaanvgkcklvlir-nGkplplskvyileiddeelkrikeakaiitednkvnGviestrilGytflfPvvlPkphvrsvlLteqdEllilGnkalWevl DVDTVCDIARENsTDPLRAAAELKDHAMAYGCTENITILC ..| . . |.. ||| || | | | .||.......| sideaveavrnv-edplvaAkklvdlaqsygaadsvsalv |
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| Phosphatase | CYR1.AA | Subfamily.PPM1E.PD | 1467-1621 | 31 | 1.6e-23 | 73.1 | In-house | 106-266 (269) | Show / Hide |
Range on Protein: 1467-1621 Range on HMM: 106-266/269 Sequence Identity: 31% (50 aa) DLLSGACSTVIYIRGKKLFAANLGDCMAILSKNnGDYQTLTKQHLPTKREEYERIRISGGYVNN---GKLDGVVDVSRAVGFFDLLPHIHASPDISVVTL | ||. . |. |....|. | ||| |.| .. |. .|.| | | . .| .|| || | . . .||. ||||.| .| |... .|.. |.|.. klksGstavvvliekdqlyvaWlGDsqallvrk-geavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklkpyvsgeadvaevel TKADEMLIVATHKLWEYMDVDTVCDIARE----NSTDPLRAAAELKDHAMAYGCTENITILC ....||.|. ||. .. ..|... .| ...| ..| .| ..| | ..|||.. dgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvv |
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| Phosphatase | CYR1.AA | Subfamily.PPM1K.PD | 1418-1622 | 28 | 5.5e-23 | 71.3 | In-house | 60-262 (264) | Show / Hide |
Range on Protein: 1418-1622 Range on HMM: 60-262/264 Sequence Identity: 28% (60 aa) IRQLERYGdETDDNIKTALRFSFLQLNKEINGMLNSVDNGAdvanlsyADLLSGACSTVIYIR-GKKLFAANLGDCMAILSKnNGDYQTLTKQHLPTKRE . ..|. | ...... | .|..|.|... |. | | ||. .|| .| |..| |.||| ||| . ||. .||| | | ..|| eeivrrll-ekekdleevlkqafeeldkklkrylefsvaea-------ellssGttatvsllrdGnelvlaslGdsrailcr-nGkakkltkdhdPerke EYERIRISGGYVNNG-----KLDGVVDVSRAVGFFDLLPH-IHASPDISVVTLT-KADEMLIVATHKLWEYMDVDTVCDIAReNSTDPLRAAAELKDHAM |||. .|| |. ...... ..|..| .|| .. . | |. . . .|| .|.. | . .. .||. | .|| .|| . . |. | ekerikaagGsvewnslgkplvnsrlamtrslGdldlkryGviatPetkslkvkhaadsflvlitdgisfvvnsqelcdlvr-lchdpeeaahavteqal AYGCTENITILCL |. .| |.. . qygsednatavvv |
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| Phosphatase | CYR1.AA | Guanylate_cyc | 1659-1816 | 20 | 6.2e-23 | 84.99 | Pfam | 1-171 (214) | Show / Hide |
Range on Protein: 1659-1816 Range on HMM: 1-171/214 Sequence Identity: 20% (35 aa) EISPPTGNLAMVFTDIKSSTFLWELFP-----NAMRTAIKTHNDIMRRQLRIY--GGYEVKTEGDAFMVAFPTPTSGLTWCLSVQLKLLDAQWPEEITSV . ...... ...|.||. .| ... . ........|. ..|... . |.|.||| ||..|... .| ..|| . . . |... .. VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY QDGCQVTDRN-GNIIYQGLSVRMGIHWGCPVPELDL---VTQRMDYLGPMVNKAARVQGVADGG--QIAMS . .| . | .. . ....|.||| | | . . . |... |. || | |.. ....| .|..| CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVS |
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| Phosphatase | CYR1.AA | Subfamily.ILKAP.PD | 1469-1591 | 30 | 1.4e-22 | 70.2 | In-house | 116-249 (298) | Show / Hide |
Range on Protein: 1469-1591 Range on HMM: 116-249/298 Sequence Identity: 30% (38 aa) LSGACSTVIYIRGKKLFAANLGDCMAILSKNNGDYQT----------LTKQHLPTKREEYERIRISGGYVNNGKLDGVVDVSRAVGFFDLL-PHIHASPD .|. ..|. . . .|. ||||| |.| ... . .. |.|.| |.. || .||. .||.|..|.. ||..|||..|. ..||.. ..||. kdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelgvistPd ISVVTLTKADEMLIVATHKLWEYMDVDTVCDIAR | ...| ||. ...| | . . vkkceLtenDlfvvlaCDGLwkvfeadevvkfil |
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| Phosphatase | CYR1.AA | Subfamily.PPM1G2.PD | 1419-1595 | 24 | 5.3e-22 | 68.1 | In-house | 67-239 (275) | Show / Hide |
Range on Protein: 1419-1595 Range on HMM: 67-239/275 Sequence Identity: 24% (46 aa) RQLERYGDETDDNIKTALRFSFLQLNKEINGMlnsvdngadvanLSYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNNGdYQTLTKQHLPTKREEY . ... . ........|. .||....|. . .| .|. ..|. |. .||. || || |.||.. ..|. | |.. .| kkiakkksfkegaleqilkdafletDeellkd------------eklkdesaGstavvvlikeeklyvanaGDsravlsskgn-vkalsfDhkPqeesek ERIRISGGYVNNGKLDGVVDVSRAVGFFDLLPH---------IHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENST .|| .||.|. .. |.. .|||.| | . . | ||. | |.. || |..| .|. . ..|.|. ||. . kriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlv |
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| Phosphatase | CYR1.AA | Subfamily.PPM1L.PD | 1363-1622 | 23 | 1.2e-20 | 63.9 | In-house | 19-271 (273) | Show / Hide |
Range on Protein: 1363-1622 Range on HMM: 19-271/273 Sequence Identity: 23% (61 aa) TLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRqlerygdetDDNIKTALRFSFLQLnkeINGMLNSVDNGAdVAN ||.|. . | | . . .| .....| . . . ...|..|..|.. | . . .. .| .| .. .|||. . .. vlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknkliel---------dadkentvpinfskl---ltdeilsvdekl-lek LSYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVN-NG--KLDGVVDVSRAVGFFDLLPH--IHASPD | ..|. . . .....| ||.|| .| ..| |. .| | . .| ||. .||.. .| .. ||..|||.| . | . . |.||| akraediaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdknlviadpd ISVVTLTKA-DEMLIVATHKLWEYMDVDTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCL | . |.||.|. ||. . . . ..|. .| | | .. |...|||.| . iltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfGakslvlesfkrGsvdnitvlvv |
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| Phosphatase | CYR1.AA | Subfamily.PPM1G.PD | 1470-1593 | 37 | 4.2e-20 | 62.2 | In-house | 307-439 (482) | Show / Hide |
Range on Protein: 1470-1593 Range on HMM: 307-439/482 Sequence Identity: 37% (49 aa) SGACSTVIYIRGKKLFAANLGDCMAILSKNnGDYQTLTKQHLPTKREEYERIRISGGYVN-NGKLDGVVDVSRAVGFF-----DLLP----HIHASPDIS ||. .| ..||||. || || ..||.| | | | | .| |||. || |. .|. .| ...|||.| ||| | ||| . .|| sGttavvaLvkgkklivanaGDsRcvlsrn-GkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalPDik VVTLTKADEMLIVATHKLWEYMDVDTVCDIAREN ..|| |..|. .| .|. . | | |.. klilteedeFlvlacDGiWnvmssqevvdFvrak |
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| Phosphatase | CYR1.AA | Subfamily.PDP.PD | 1384-1523 | 26 | 4.6e-18 | 55.5 | In-house | 83-222 (409) | Show / Hide |
Range on Protein: 1384-1523 Range on HMM: 83-222/409 Sequence Identity: 26% (38 aa) DDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLErygdETDDNIKTALRFSFLQLNKEIN-GMLNSVdNGADVANLSYADLLSGACSTVIYIRGK .| | |. .|. |.. .. .... . . | . ..|| ....... ||. .||.| |.| |... . ..... . |||||... .|.|.. lkellsilklekkpndsvlkeskklykeslkkyvqelle----akelkveealkkaFlrlDkdislealkkl-eekvleeavlkvalsGacallaliegt KLFAANLGDCMAILSKNNGDY----QTLTKQHLPTKREEYERIRI |. || ||| |.| ..... ..|.|.. . .|| |||. elhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikk |
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| Phosphatase | CYR1.AA | Subfamily.PPM1D.PD | 1418-1537 | 26 | 4.9e-14 | 42.1 | In-house | 67-184 (311) | Show / Hide |
Range on Protein: 1418-1537 Range on HMM: 67-184/311 Sequence Identity: 26% (31 aa) IRQLERYGDETDDNIKTALRFSFLQLNKEingMLNSVDNGADVANLSYAdlLSGACSTVIYIRGKKLFAANLGDCMAILSKNNG-----DYQTLTKQHLP |.. . . . .... |.| .||..... | .. .. . .. .. .|. .|. ||..||. |. || ..|......|||.| | . || || ikkqkkflssepedvleAireaflathea---mkkklaeWpktksglls--taGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkP TKREEYERIRISGGYVNNGklDGVV |. .|| | . || espeEkerieelGGevaak--sGvk |
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| Phosphatase | CYR1.AA | Subfamily.PDP.PD | 1549-1592 | 27 | 4e-06 | 16.2 | In-house | 281-324 (409) | Show / Hide |
Range on Protein: 1549-1592 Range on HMM: 281-324/409 Sequence Identity: 27% (12 aa) LPHIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARE | . |.|.. |...| |..|| ||. .. ..| .. | PPYltaePevtshklrendkFLvlatDGLwdllsneevvslVge |
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