Gene PTC3
PTC3
Species: S.cerevisiae
Alias: PTC3
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTC3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTC3.AA | Subfamily.PPM1G2.PD | 13-291 | 55 | 2.5e-128 | 417.1 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 13-291 Range on HMM: 1-275/275 Sequence Identity: 55% (154 aa) EHHSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELLKDEK |..||... .|.|...|||.|..||||||.|..||..||...||....||||||..||...|.|.|....|..|||.|.|||.|.|.||.|| ||||||| eassganariavgvssmqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdek LKDDHSGCTATVILVSQLKklLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTC |||...|.||.|.|... | |..||.||||.|||. ||.||.||||||. |||.||.||.||||..|||||||||||.||||||.|.|..|.||.||. lkdesaGstavvvlikeek--lyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivta VPDIICHNLNyDEDEFVILACDGIWDCLTSQECVDLVHYGISQGnMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIV |||.....|. ..|||..||||||||.||..|.||||.. ...| ..|..|.....| |..|... .|.|||||.. || vPDvlvkkld-eddeflvLaCDGiWDvltnkevvdlvrerlvsg-akldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | PTC3.AA | PP2C | 22-280 | 38 | 4.2e-116 | 396.8 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 22-280 Range on HMM: 1-284/284 Sequence Identity: 38% (111 aa) TAFGLCAMQGWRMSMEDAHIVEPNLLAE-SDEEHLAFYGIFDGHGGSSVAEFCGSKMI----SILKKQESFKSG---MLEQCLIDTFLA--TDVELLK-- ..|.|.|||||..|||||. .||.... |.... .|...||||||. .|..|.... |||...||..| ..||.|...||. ||... . WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP -DEKL----KDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSK----AMSFDHKPTLLSEKSRIVAADGFVE---MDRVNGN-LALSRAIGDFE .|. ...||||||...... |..|..|| ||||.||...||.. ....||||. .|..||..|.|.|. . ||||. ||.|||.|||. WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFH FKSNTKLGPHEQVVTCVPDII-CHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSG .|.| ...|.||.||..||| .|....|.|||.||||||.||....||..|.|....|..| ...... ..|| |... .| .. YKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN-DPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | PTC3.AA | Group.PPM.PD | 15-316 | 33 | 4.2e-88 | 286.0 | In-house | 31-344 (459) | Show / Hide |
Range on Protein: 15-316 Range on HMM: 31-344/459 Sequence Identity: 33% (109 aa) HSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESdeehlAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKS------------------GMLEQCL .| .. ...| ..||||| .|||.|.. |. . .|.|.||||||...|||. .|. .||||| ..|. ....| sagsgnglrygvasmqgwrkemEDrhvivenfdnnd-----sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkkal IDTFLATDVELLKDEKLKD---DHSGCTATVILVsQLKkLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEM-DRVNGNLALSRAI ..||..| .| .... |. . ||.||.|.|. . | |..|| |||| ||.. |.....| ||||. .|..|| .| |.||. .|||| ||.|||.| rsafleldedlseeanekeepgkdsGtTAvvali-ngk-klyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRal GDFEFKSntklgpHEQVVTCVPDIICHNLNYDeDEFVILACDGIWDCLTSQECVDLVHYGISQ----GNMTLSDISSRIVDVCCSP-TTeGSGIGCDNMS |...|. .||.|.. ||. ..|. . |||..||.||.||.|...|.|..|. ... . .|..|..|.|| . .. .| |.| .|||... Gdhdlkk------eeqmvsaePdvsvvkltee-deflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgst-gdgtscDNiT ISIVALLKENESESQWFERMRSKNYNIQT .| | . . ... ... .... .... vivvtlndamrrqleivkkeevleeelaf |
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| Phosphatase | PTC3.AA | PP2Cc | 13-291 | 26 | 1.5e-86 | 294.73 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 13-291
Range on HMM: 1-338/338
Sequence Identity: 26% (98 aa)
EHHSGTDCLTAFGL--CAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSG--------------------
. .| . ..|. ..||||| .|||||.. | |.|.||||||...|..|.... ..|.....|...
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMW
------MLEQCLIDTFLATDVELLKDEKLKDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGN----------SKAMSFDHKPTLLSEKSRIVAAD
..| .|...||..| |. |||.|.|.. | |..|| |||| ||...|| .....|||| .|..|| .|
HDKWFEDWEDALRKAFLRMDEEI------------CTAVVALIRGNK--LYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAG
G--------FVEMD-----RVNGN---LALSRAIGDFEFKSNT----------------KLGPHEQVVTCVPDIICHNLN-----YDEDEFVILACDGIW
| .|. . ||||. ||.|||.||...| .|.. |. |...||. |.|. ...|.|.||.|||.|
GRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLW
DCLTSQECVDLVHYGISQG----------------------NMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIV
|....|| ||.|. .... .. ..... |..| . ||||.. .|
DVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----------CDNMTVIVV
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| Phosphatase | PTC3.AA | Family.PPM.PD | 14-310 | 35 | 2.3e-81 | 263.8 | In-house | 7-303 (495) | Show / Hide |
Range on Protein: 14-310
Range on HMM: 7-303/495
Sequence Identity: 35% (111 aa)
HHSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESdeeHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKS------------GMLEQCLIDTFL
.. . ...| ..||||| .||||| | || . .....|.||||||...|||. .|. .|||||...|. ....|..||..|
teasssnglrygvasmqgwrsemeDahvvvenlenne---dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafl
ATDVELLKDEKLKD--DHSGCTATVILVSQLKklLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEM--DRVNGNLALSRAIGDFEF
|| .. . |. . ||.||.|.|... | |..|| |||| ||. |.....| ||||. .|..|| .| |.|.. |||| ||.|||.|||..|.
eldeelseelneksagkdsGtTAvvvlirgkk--lyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdl
KSntklgpHEQV-VTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEgsgigcDNMSISIVALLKE
.||. |...||| ..|. .||||..||.||.||.|...|.|.||. ... . .|. |. ..|| . .. .. ||... .||| .. .
kk------eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsr------DNiTvlvvalyen
NESESQWFERMRSK
... .. .|
ikqqnrfvlnknsl
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| Phosphatase | PTC3.AA | Subfamily.PPM1A.PD | 17-302 | 36 | 2e-79 | 257.1 | In-house | 5-287 (309) | Show / Hide |
Range on Protein: 17-302 Range on HMM: 5-287/309 Sequence Identity: 36% (106 aa) GTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLaeSDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFK-------SGMLEQCLIDTFLATDVELLK |.. .|| .|||||..|||||.. .| | . .|...||||.||.|...|........ ..|.|| .... | ..||..| .. | gegnglryglssmqgwRvemEDahtavidlp--sklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirk DEKLK--DDHSGCTATVILVSqlKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHE . .|. |.||.||.|.||| .| |..|| ||||.||| |... .. ||||. .|| || .|.|.| ..||||.||.|||.||...|........| lvelskgedksGsTavvvlvs--pkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpekkate QVVTCVPDIICHNLNyDEDEFVILACDGIWDCLTSQECVDLVHYGISQGnMTLSDISSRIVDVCCSpttEGSgigCDNMSISIVALLKENESESQ |.|. |.... . . .||||..|||||||| ....| ...|. .. . |. ......| | . .||||||. .|.| . . ... qlvspepevtvierd-eedeflvlacDGiwDvmsneevaefvksrlevt-ddleevanelldtcLe---kgs---rDNmsvilvllpgapkvsee |
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| Phosphatase | PTC3.AA | Subfamily.PPM1G.PD | 117-292 | 48 | 1.7e-60 | 195.7 | In-house | 306-481 (482) | Show / Hide |
Range on Protein: 117-292 Range on HMM: 306-481/482 Sequence Identity: 48% (85 aa) HSGCTATVILVSQlkKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMD-RVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPD ||.||.| || . | || || ||||.||| |. .|.|||| |..|| .| | |..| |||| | ||||.|| .| |..|...|| .. .||| dsGttavvaLvkg--kklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalPD IICHNLNyDEDEFVILACDGIWDCLTSQECVDLVHYGISQG--NMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIVA . |. .||||..|||||||....||| || |. .... . .||.| ...| | .| |.| | |||||.. || ikklilt-eedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvvivq |
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| Phosphatase | PTC3.AA | Subfamily.PPM1E.PD | 26-291 | 32 | 9e-46 | 146.4 | In-house | 15-267 (269) | Show / Hide |
Range on Protein: 26-291 Range on HMM: 15-267/269 Sequence Identity: 32% (85 aa) LCAMQGWRMSMEDAHIVEPN---LLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLeQCLIDTFLATDVELLKDEKLKDDHSGCTA . |... | ||| |.. .. |. .||.. ||...||||||. |.. ... . | .||..|. . . | ..| .|| .|. .. .||.|| iaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa-ealkeafkltDerflqkaereklksGsta TVILVSQLKklLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFV---EMDRVNGNLALSRAIGDFEfksntklgpHEQVVTCVPDIICH |.|... . | | |||...| |. . ||| ||.|| .|.|.| .. ||||.|..|||||| .... |. .|. .|. ...... vvvliekdq--lyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvk---------lkpyvsgeadvaev NLNyDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCcspTTEGSGigcDNMSISIV ||||||.|| .. .| |.||. ...|...||... .|. . .|| ||... .| eld-gsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaa---keagss---Dnitvvvv |
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| Phosphatase | PTC3.AA | Subfamily.ILKAP.PD | 27-251 | 33 | 4.2e-45 | 144.4 | In-house | 14-250 (298) | Show / Hide |
Range on Protein: 27-251 Range on HMM: 14-250/298 Sequence Identity: 33% (80 aa) CAMQGWRMSMEDAHIVEPNLLAE-----SDEEHLAFYGIFDGHGGSSVAEFCGSKMISILK-----KQESFKSGMLEQCLIDTFLATDVELLKDEKLK-- .| | |||||.. .| . | ....|..||||.|| .||. .|. . .. .. |.| ...||.|.| .|| |.|| . . aerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklaskakP DDHSGCTATVILVsqLKKLLICANSGDSRTVLSTGG-NSK----------AMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTkl .|.||.|.|| .. | || |||..|| ... .| ||.|. |. || | |.|. .||.||. ||.||| .||. vWkdGstavvvlv--vdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelg-- gpheqvVTCVPDIICHNLNYDeDEFVILACDGIWDCLTSQECVDLVHY |.. ||. .|. . | ||.|||||.|. .. .| |. . ------vistPdvkkceLten-DlfvvlaCDGLwkvfeadevvkfilk |
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| Phosphatase | PTC3.AA | Subfamily.PPM1L.PD | 27-250 | 34 | 2e-43 | 138.9 | In-house | 17-240 (273) | Show / Hide |
Range on Protein: 27-250 Range on HMM: 17-240/273 Sequence Identity: 34% (81 aa) CAMQGWRMSMEDAHIVEPNLlaeSDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQ----ESFKSGM----LEQCLIDTFLATDVELLKDEKLKDDHS ...| | ||| ..| .. ... . |...|||||| |||. ... .|.. .. | .. | | |. | .||.| . | .|.| ysvlGrrprmedrfeieedi---knktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraedia GCTATVILVSQLKklLICANSGDSRTVLS-TGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMD---RVNGNLALSRAIGDFEFKSntklgphEQVVTCVP | . ||.. . || || |||| || . |.. .|||||| . |. || | ||. .. ||.| ||.|||.||..| ...| |||.. Gttalialvqesd--livanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkd-------knlviadp DIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVH .|. . ||.|||.||.||... .| | .. diltfdlddhkpeflilasdGlwdtfsneeavrfik |
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| Phosphatase | PTC3.AA | Subfamily.LRR-PP2C.PD | 25-254 | 34 | 4e-43 | 137.7 | In-house | 13-228 (257) | Show / Hide |
Range on Protein: 25-254 Range on HMM: 13-228/257 Sequence Identity: 34% (81 aa) GLCAMQGWRMSMEDAHIVEPNLLAESDEEHlafYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELlkdeKLKDDHSGCTATV | . | | | .||| .. . .|||.. | .||||||.. |.|. .. ||.. .. ...| ... .... . .. . |.||... gfsdmiGrrptmedelviyGsfrdksdedy---yalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqi----serpkfiGttaas ILVSQlkKLLICANSGDSRTVLS-TGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMD----RVNGNLALSRAIGDFeFksntkLGPHeqvVTCVPDIICH |. . . . || |||| ||. | .| .|.||||. ||. || .. |.| . ||||.||.|||.||| | |. |. ||. . . vliie--dkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds-f-----lePf---vvpdPdlsqs NLNYDEDEFVILACDGIWDCLTSQECVDLVHyGIS . .|.|.||||||||| .. .| |..| ||| leiskkdkflilacdGiwdlisdeeaveiva-gis |
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| Phosphatase | PTC3.AA | Subfamily.PPM1K.PD | 28-251 | 35 | 2.2e-36 | 115.5 | In-house | 16-233 (264) | Show / Hide |
Range on Protein: 28-251 Range on HMM: 16-233/264 Sequence Identity: 35% (77 aa) AMQGWRMSMEDAHIvepnlLAESDeEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQEsFKSGMLEQCLIDTFLATDVELLKDEKLK-----DDHSGCTA ...| |. || |.| | ..| ....|||||||| |.|. |. |... | ||. | . |. | .| . ...|| |||| |. . sliGkraenedrfk-----lkeld-pdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkrylefsvaeaellssGtta TVILVSQLKKLLIcANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEM-----DRVNGNLALSRAIGDFEFKSNTklgpheqvVTCVPDII ..| . |. ||||..| |..| .. ||.| .|| || ||.|.||. .||. ||..|..||...|.| |. ......| |..| || tvsllrdGnelvl-aslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryG--------viatPetk CHNLNYDEDEFVILACDGIWDCLTSQECVDLVHY | . ..||| |||. slkvkhaadsflvlitdgisfvvnsqelcdlvrl |
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| Phosphatase | PTC3.AA | Subfamily.PPM1D.PD | 28-291 | 30 | 5.6e-32 | 101.3 | In-house | 14-311 (311) | Show / Hide |
Range on Protein: 28-291
Range on HMM: 14-311/311
Sequence Identity: 30% (87 aa)
AMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGM---LEQCLIDTFLATDVELLKDEK----LKD-D--H
| || | ||| . . ..|. || ..|||||| |.| ....| .|||. | | . . . ..|||| .. | .|. . .| ||
adqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktksgllst
SGCTATVILVSQLKklLICANSGDSRTVLSTGGN------SKAMSFDHKPTLLSEKSRIVAADGFVEMD----RV---------NGN--------LALSR
.|... . | | |. |||..||.. . .| . |||| ..|| || . | | . ||||. ||..|..||. . |.|
aGttasvviirrek--lyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprlehngptvideiPFLavaR
AIGDFeFKSNTKLgpHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNM---TLSDISSRIVDVCCSpTTEGSGIGCDNMS
.| || .||. ..|. .|..|.||| ||.|..||... |..|. ... . ........|. . ... . .||.|. .|
slGDl-Wsynaks--geyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealq-rwrskklraDnvs
ISIV
vivv
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| Phosphatase | PTC3.AA | Subfamily.PPM1G.PD | 21-114 | 42 | 1.2e-26 | 84.0 | In-house | 9-97 (482) | Show / Hide |
Range on Protein: 21-114 Range on HMM: 9-97/482 Sequence Identity: 42% (39 aa) LTAFGLCAMQGWRMSMEDAHIVEPNLlaesDeEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELLKDEKLK ..| |||||| |||||| . .| | |. ......|||||. ||..| .|. .||.....| | .|..| ..||. | .||..||| elsygasamqGWRvsmeDahncildl----d-edtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkllteeilk |
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| Phosphatase | PTC3.AA | Subfamily.PDP.PD | 100-265 | 24 | 5.4e-18 | 55.6 | In-house | 147-337 (409) | Show / Hide |
Range on Protein: 100-265 Range on HMM: 147-337/409 Sequence Identity: 24% (47 aa) FLATDVELLKDEKLKDDHSGCTATVILVSQLKklLICANSGDSRTVLSTGG-----NSKAMSFDHKPTLLSEKSRIVAAD------GFVEMDRVNGNLAL . ... . |.. || || .|.. |... . | || ||.|.|| . .....| |. . .| .|| .. . .|. |.|| lkkleekvleeavlkvalsGacallaliegte--lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaP SRAIGDFEFKSNTKLGPHE----------QV--------VTCVPDIICHNLNyDEDEFVILACDGIWDCLTSQECVDLVHYGISQgNMTLSDISS .|| ||...| . .| . .. .| |... |.|. .| |..|| ||.||.|...| |.||. ..... ..... lRAFGdvryKwskelqkkvlekllevkvvepkdyktPPYltaePevtshklr-endkFLvlatDGLwdllsneevvslVgehlak-kknkakvaa |
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| Phosphatase | PTC3.AA | Subfamily.PHLPP.PD | 51-250 | 24 | 2.6e-12 | 36.5 | In-house | 35-227 (257) | Show / Hide |
Range on Protein: 51-250 Range on HMM: 35-227/257 Sequence Identity: 24% (51 aa) DEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESfKSGMLEQCLIDTFLATDVELLKD-EKLkddhsGCTATVILVSQL------KKLLICANSGDSR |. | ||..|| | ... | ..|| . . |. |. . ...| .. .| .. .|| |..| .| . . |.|| |. ..| aenveavyGlidGdrnselpsllqctmadvlkeevq-kdkneevyianillvshrklGeaGqkl-----Gasallirikedrvdiassftltaanvgkck TVLSTGGN----SKAMSFDHKPtllSEKSRIVAADGFVE-MDRVNGNLALSRAIGDFEFksntklGPheqVVTCVPDIICHNLNyDEDEFVILACDGIWD | .| ||..... . | .|| | .... ..||| .. .| .| . | || | .|. ..||..|| ...|. | .| lvlirnGkplplskvyileidd---eelkrikeakaiitednkvnGviestrilGytfl------fP---vvlPkphvrsvlLt-eqdEllilGnkalWe CLTSQECVDLVH |. |. vlsideaveavr |
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| Phosphatase | PTC3.AA | Subfamily.PPM1H.PD | 96-170 | 33 | 8.7e-12 | 34.7 | In-house | 142-212 (402) | Show / Hide |
Range on Protein: 96-170 Range on HMM: 142-212/402 Sequence Identity: 33% (25 aa) LIDTFLATDVELLKDEKLKDDHSGCTATVILVsqLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTllSEKSRI | . || | . .... .. |||| | || |.. | ||.|||| .|.. ......| |. | .|. |. lesaflemDeqiarereayrikGGCtalvalv--llgklYvanaGDsRailvrkdeiiplsadftPe--teRqRl |
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| Phosphatase | PTC3.AA | Subfamily.PPM1H.PD | 180-252 | 28 | 2.2e-09 | 26.8 | In-house | 277-352 (402) | Show / Hide |
Range on Protein: 180-252 Range on HMM: 277-352/402 Sequence Identity: 28% (21 aa) DRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLN---YDEDEFVILACDGIWDCLTSQECVDLVHYG |. . .. .| .|| | | . ....||.. .|. .||. .||| ||.|| |. .| .|. aRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrev |
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| Phosphatase | PTC3.AA | Subfamily.TAB1.PD | 115-240 | 26 | 6.2e-06 | 15.5 | In-house | 133-269 (336) | Show / Hide |
Range on Protein: 115-240 Range on HMM: 133-269/336 Sequence Identity: 26% (35 aa) DDHSGCTATVILVSqLKKLLICANSGDSRTVLSTGG----NSKAMSFDHKPTLLSEKSRIVAA---DGFVEMDRVNGNLALSRAIGDFEFKS----NTKL . || | |. . | . | || |||| .| . . | .| || | |. . . .. |. |.|||.. |.. | .. seisgGttavvali-lnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvl G-PHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCL . ||| | .|..| ||. . | ssAkgePiiatPdingpkdindlegfllLmSdGlykal |
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