Gene PTC2
PTC2
Species: S.cerevisiae
Alias: PTC2
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTC2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTC2.AA | Family.PPM.PD | 12-310 | 34 | 4.4e-82 | 266.1 | In-house | 5-304 (495) | Show / Hide |
Range on Protein: 12-310 Range on HMM: 5-304/495 Sequence Identity: 34% (106 aa) KESHSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSdkdHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHE------------GNLPRALIDT ... .. .. ...| ..||||| .|||.| | .. .....|.|||||||..||.. .|...||..|..... .. .|| .. arteasssnglrygvasmqgwrsemeDahvvvenlenne---dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrka FINTDVKLLQDPVMKE--DHSGCTATSILVSKSQnlLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEM--DRVNGNLALSRAIGDF | ..| .| .. |. . ||.||...|..... |...|||||| || .|.|..||.||||. .|..|| .| |.|.. |||| ||.|||.||| fleldeelseelneksagkdsGtTAvvvlirgkk--lyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdf EFKSnpklgpEEQI-VTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGL-REGKTLNEISSRIIDVCCAPTTEgtgigcDNMSIVVVALL ..|. |||. |...||| . |. . |||..||.||.||.|.....|.||. | .....|.||. ...| . |. ..||....|||| .. . dlkk------eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsr------DNiTvlvvaly KEGEDVAQWSDRMKSKA . . .| enikqqnrfvlnknslm |
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| Phosphatase | PTC2.AA | Subfamily.PPM1G2.PD | 13-290 | 54 | 5e-128 | 416.1 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 13-290 Range on HMM: 1-275/275 Sequence Identity: 54% (151 aa) ESHSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLPRALIDTFINTDVKLLQDPV |..|||.. .|.|...|||.|..|||.||||...|.|||....|....||||||||||.|.|.|........|||.||.| ..|.|.|..|| .||.| eassganariavgvssmqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdek MKEDHSGCTATSILVSKSQnlLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTC .|....|.||...|..... |...||||||.||...||.||||.||||. .|||.||.||.||||..|||||||||||.||||||.| |..|||||||. lkdesaGstavvvlikeek--lyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivta VPDILEHSLDyDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVV |||.| ..|| ..|||..||||||||.||....||||. |..|..|.||.....| |.||... ||.|||||..|.| vPDvlvkkld-eddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | PTC2.AA | PP2C | 22-279 | 39 | 4.2e-116 | 396.81 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 22-279 Range on HMM: 1-284/284 Sequence Identity: 39% (113 aa) TAFGLCAMQGWRMSMEDSHILEPNVLTK-SDKDHIAFYGIFDGHGGAKVAEYCGNKIV----EILQEQKSFHEG---NLPRALIDTFIN--TDVKLLQ-- ..|.|.|||||..|||.|...|| . |.||...|...||||||...|.||.... .||.|.|||.|| .. .||...| . ||... . WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP -DPVM----KEDHSGCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAK----ALSYDHKPTLASEKSRIVAADGFVE---MDRVNGN-LALSRAIGDFE .. . . .||||||.........|.| . |.||||.||...|||. .|.|||||. .|..||..|.|.|. . ||||. ||.|||.|||. WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFH FKSNPKLGPEEQIVTCVPDIL-EHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTG .|.|....|.||.||..||| || ...|.|||.||||||.||....|...|.|. .. ......|.. ...| |.|. .| .. YKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | PTC2.AA | PP2Cc | 13-290 | 27 | 3.8e-97 | 329.98 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 13-290
Range on HMM: 1-338/338
Sequence Identity: 27% (102 aa)
ESHSGADSLTAFGL--CAMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEG--------------------
.| .| .| ..|. ..||||| .|||.|. | |.|.|||||| ..|.||.....|.|.|...||..
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMW
------NLPRALIDTFINTDVKLLQDPVMKEDHSGCTATSILVSKSQNLLVCGNAGDSRTVLATDGN----------AKALSYDHKPTLASEKSRIVAAD
.. .||...| .| .. |||. .|... . | ..|.|||| || ..|| |..|..|||| ..|..|| .|
HDKWFEDWEDALRKAFLRMDEEI------------CTAVVALIRGNK--LYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAG
G--------FVEMD-----RVNGN---LALSRAIGDFEFK---------------SNPKLGPEEQIVTCVPDILEHSLD-----YDRDEFVILACDGIWD
| .|. . ||||. ||.|||.||...| .|.|...|..|...||. .| |. .. |.|.||.|||.||
GRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWD
CLTSQDCVDLVHLGLREGKTLNEI-----------------------SSRIIDVCCAPTTEGTGIGCDNMSIVVV
....|. ||.|. ||... . .. .. .. |.. ||||...||
VMSNQEVVDIVRKCLRKWHHK-PVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI---------CDNMTVIVV
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| Phosphatase | PTC2.AA | Group.PPM.PD | 14-316 | 34 | 2.6e-88 | 286.7 | In-house | 30-347 (459) | Show / Hide |
Range on Protein: 14-316 Range on HMM: 30-347/459 Sequence Identity: 34% (113 aa) SHSGADSLTAFGLCAMQGWRMSMEDSHILEPNVLTKSdkdhiAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHE------------------GNLPRA | .| .. ...| ..||||| .|||.|.. |. .. .|.|.|||||||..||.. .|...||..|..... ...|| ssagsgnglrygvasmqgwrkemEDrhvivenfdnnd-----sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkka LIDTFINTDVKLLQDPVMKE---DHSGCTATSILVskSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEM-DRVNGNLALSRA ..| ..| .| .. || . ||.||...|. ... |...|||||| || ..|.|..||.||||. .|..|| .| |.||. .||||||.|||.| lrsafleldedlseeanekeepgkdsGtTAvvali--ngkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRa IGDFEFKSnpklgpEEQIVTCVPDILEHSLDYDrDEFVILACDGIWDCLTSQDCVDLVHLGLRE-----GKTLNEISSRIIDVCCAP-TTeGTGIGCDNM |...|. |||.|.. ||. . |. . |||..||.||.||.|.....|..|. | . .|.|.||..|..| . |. .||.| .|||.... lGdhdlkk------eeqmvsaePdvsvvkltee-deflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgst-gdgtscDNi SIVVVALLKEGEDVAQWSDRM--KSKAHRTSVR || | . . .. .. . .. . |. Tvivvtlndamrrqleivkkeevleeelafmva |
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| Phosphatase | PTC2.AA | Subfamily.PPM1A.PD | 16-292 | 36 | 1.4e-81 | 264.2 | In-house | 4-278 (309) | Show / Hide |
Range on Protein: 16-292 Range on HMM: 4-278/309 Sequence Identity: 36% (101 aa) SGADSLTAFGLCAMQGWRMSMEDSHILEPNVltKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFH-------EGNLPRALIDTFINTDVKLL .|.. .|| .|||||..|||.|. .. .| . .|...||||.|.||..||.....|.. |...|. . .. || ..|...| |. egegnglryglssmqgwRvemEDahtavidl--psklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekir QDPVMK--EDHSGCTATSILVSksQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPKLGPE ... .. ||.||.||...||| .. |.. |.||||.||. .|... ..||||. ..|| || .|.|.| ..||||.||.|||.||...|..|..... klvelskgedksGsTavvvlvs--pkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpekkat EQIVTCVPDILEHSLDyDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEgtgigcDNMSIVVVAL ||.|. |.. . | . |||..|||||||| ..... ...|. |. .. |.|......| | ..||||...|.| eqlvspepevtvierd-eedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsr------DNmsvilvll |
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| Phosphatase | PTC2.AA | Subfamily.PPM1G.PD | 117-291 | 48 | 1.3e-60 | 196.1 | In-house | 306-481 (482) | Show / Hide |
Range on Protein: 117-291 Range on HMM: 306-481/482 Sequence Identity: 48% (86 aa) HSGCTATSILVSKsQNlLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEMD-RVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPD ||.||. || . .. |. ||||||.||. .|.| ||.|||| |..|| .| | |..| |||| | ||||.|| .| | .|..|||... .||| dsGttavvaLvkg-kk-livanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalPD ILEHSLDyDRDEFVILACDGIWDCLTSQDCVDLVHLGLREG---KTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVA .. | . |||..|||||||....||. || |. |.|. |.| || ...| | || |.| | |||||..|.| ikklilt-eedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvvivq |
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| Phosphatase | PTC2.AA | Subfamily.PPM1E.PD | 25-291 | 35 | 5.7e-48 | 153.6 | In-house | 14-268 (269) | Show / Hide |
Range on Protein: 25-291 Range on HMM: 14-268/269 Sequence Identity: 35% (92 aa) GLCAMQGWRMSMEDSHILEPN--VLTK-SDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLpRALIDTFINTDVKLLQDPVMKEDHSGCT . |... | ||| |. .. | . .|....||...|||||| . |.| ... | | .|....| . .|| ..| .|| ..|| ... .||.|| siaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa-ealkeafkltDerflqkaereklksGst ATSILVSKSQnlLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFV---EMDRVNGNLALSRAIGDFEFKsnpklgpeeQIVTCVPDILE ..|..|.| | . |||...| .|.| | ||| ||.|| .|.|.| .. ||||.|..|||||| . |. |. .|. | .|| . .... avvvliekdq--lyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk---------pyvsgeadvae HSLDyDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGK-TLNEISSRIIDVCcapTTEGTGigcDNMSIVVVA ||||||.|| .. .. |.||. |..|. .|.|.. ... . .| ||...||| veld-gsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaa---keagss---Dnitvvvvf |
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| Phosphatase | PTC2.AA | Subfamily.ILKAP.PD | 27-252 | 30 | 2.5e-45 | 145.1 | In-house | 14-251 (298) | Show / Hide |
Range on Protein: 27-252 Range on HMM: 14-251/298 Sequence Identity: 30% (73 aa) CAMQGWRMSMEDSHILEPNVLTK-----SDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQ-----EQKSFHEGNLPRALIDTFINTDVKLLQDPVMKE- .| | |||.|.. .. .. | ....|..||||.| . .|.. .|. . . |. |... .. ..|.|.| .|| ..|. .. aerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklaskakP -DHSGCTATSILVSksQNLLVCGNAGDSRTVLATD-GNAK----------ALSYDHKPTLASEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNPkl .|.||...|| .| | .| |||..||| ... ||.||.|. |. || | |.|. .||.||. ||.||| .||. vWkdGstavvvlvv--dnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelg-- gpeeqiVTCVPDILEHSLDyDRDEFVILACDGIWDCLTSQDCVDLVHLG |.. ||. |. ..| ||.|||||.|. .. .. |. . ------vistPdvkkceLt-enDlfvvlaCDGLwkvfeadevvkfilkv |
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| Phosphatase | PTC2.AA | Subfamily.LRR-PP2C.PD | 24-250 | 36 | 8.5e-44 | 139.9 | In-house | 12-225 (257) | Show / Hide |
Range on Protein: 24-250 Range on HMM: 12-225/257 Sequence Identity: 36% (81 aa) FGLCAMQGWRMSMEDSHILEPNVLTKSDKDHiafYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLPRALIDTFINTDVKLLQDPvmkeDHSGCTAT | . | | | .|||. .. . |||.|. | .|||||| . |... ... ||.| .. | ..| ... ...... . |. |.||.|.|. . vgfsdmiGrrptmedelviyGsfrdksdedy---yalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqiserp----kfiGttaa SILVSKsqNLLVCGNAGDSRTVLA-TDGNAKALSYDHKPTLASEKSRIVAADGFVEMD----RVNGNLALSRAIGDFEFksNPklgpeeqIVTCVPDILE . . | |||| ||. || || ||.||||. ||. || .. |.| . ||||.||.|||.||. .| |. ||. . . .| svliie--dkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfl--eP-------fvvpdPdlsq HSLDYDRDEFVILACDGIWDCLTSQDCVDLVH .|.||||||||| .. .. |..| sleiskkdkflilacdGiwdlisdeeaveiva |
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| Phosphatase | PTC2.AA | Subfamily.PPM1L.PD | 27-255 | 36 | 2.9e-42 | 135.1 | In-house | 17-245 (273) | Show / Hide |
Range on Protein: 27-255 Range on HMM: 17-245/273 Sequence Identity: 36% (85 aa) CAMQGWRMSMEDSHILEPNVltkSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQ----KSFHEG----NLPRALIDTFINTDVKLLQDPVMKEDHS ...| | ||| ..| .. ..| .. |...|||||| ||.. ...|. .... .. .| | . | | . | |||..|| .|.|| ysvlGrrprmedrfeieedi---knktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraedia GCTATSILVSKSQnlLVCGNAGDSRTVLA-TDGNAKALSYDHKPTLASEKSRIVAADGFVEMD---RVNGNLALSRAIGDFEFKsnpklgpEEQIVTCVP ||..|. |. | |||| || ..|.| ||.|||| |. || | ||. .. ||.| ||.|||.||..| ....| |||| Gttalialvqesd--livanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk-------dknlviadp DILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLRE || . ||.|||.||.||... .. | .. | | diltfdlddhkpeflilasdGlwdtfsneeavrfikerlke |
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| Phosphatase | PTC2.AA | Subfamily.PPM1K.PD | 23-257 | 32 | 4.3e-37 | 117.9 | In-house | 11-239 (264) | Show / Hide |
Range on Protein: 23-257 Range on HMM: 11-239/264 Sequence Identity: 32% (76 aa) AFGLCAMQGWRMSMEDSHILepnvltKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKsFHEGNLPRALIDTFINTDVKLLQDPV-----MKEDH | ...| |. || | | .... ....||||||. |... .|. ||... . .| .| . | . | . | || ... || ||| |. svGkdsliGkraenedrfkl------keldpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkrylefsvaeaells SGCTATSILVSKSQNLlVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVEM-----DRVNGNLALSRAIGDFEFKSNpklGpeeqiVTC . ..| | . ||||..| .|.|| |. ||.| .|| || ||.|.||. .||. ||..|..||...|. | | |. . ... sGttatvsllrdGnel-vlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkry---G-----via VPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGK ..| |..| ||| . ..||. |||.| . tPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrlchdpee |
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| Phosphatase | PTC2.AA | Subfamily.PPM1G.PD | 16-115 | 39 | 5.7e-28 | 88.4 | In-house | 4-98 (482) | Show / Hide |
Range on Protein: 16-115 Range on HMM: 4-98/482 Sequence Identity: 39% (39 aa) SGADSLTAFGLCAMQGWRMSMEDSHilepNVLTKSDKDhIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEGNLPRALIDTFINTDVKLLQDPVMKE .... ..| |||||| ||||.| |.... |.| .......|||||. ||.|| .|. ..|.|.|...||.. .|| ..|.. | |||.. ..|| desneelsygasamqGWRvsmeDah----ncildlded-tslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkllteeilke |
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| Phosphatase | PTC2.AA | Subfamily.PPM1D.PD | 28-179 | 27 | 7e-21 | 64.9 | In-house | 14-179 (311) | Show / Hide |
Range on Protein: 28-179 Range on HMM: 14-179/311 Sequence Identity: 27% (46 aa) AMQGWRMSMEDSHILEPNVLTKSDKDHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHE---GNLPRALIDTFINTDVKLLQD----PVMKED-H-- | || | ||| . . .... || ..|||||| . |.. ..... ...|| | .. .|. ..|..| .. . ||. .| adqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktksgllst SGCTATSILVSKsqNLLVCGNAGDSRTVLATDGN------AKALSYDHKPTLASEKSRIVAADGFVEM ||. ... . . | .. |||..||... . || | |||| .|| || . | | . aGttasvviirr--eklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaa |
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| Phosphatase | PTC2.AA | Subfamily.PDP.PD | 99-264 | 26 | 1.4e-17 | 54.2 | In-house | 146-337 (409) | Show / Hide |
Range on Protein: 99-264 Range on HMM: 146-337/409 Sequence Identity: 26% (51 aa) TFINTDVKLLQDPVMKEDHSGCTATSILVSKSQnlLVCGNAGDSRTVLAT---DG--NAKALSYDHKPTLASEKSRIVAAD------GFVEMDRVNGNLA .. ... | |.. |.| || .|. |... . | |.||.|.||.. .| .|..|| |. . ..| .|| .. . .|. |.|| alkkleekvleeavlkvalsGacallaliegte--lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLa LSRAIGDFEFKSNPKLGPEE-------Q-----------IVTCVPDILEHSLDyDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISS .|| ||...| . .| . . .| |....| | .| |..|| ||.||.|.... |.||. | .| ..... PlRAFGdvryKwskelqkkvlekllevkvvepkdyktPPYltaePevtshklr-endkFLvlatDGLwdllsneevvslVgehlakkknkakvaa |
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| Phosphatase | PTC2.AA | Subfamily.PPM1D.PD | 186-290 | 30 | 3.7e-15 | 46.1 | In-house | 207-311 (311) | Show / Hide |
Range on Protein: 186-290 Range on HMM: 207-311/311 Sequence Identity: 30% (32 aa) LALSRAIGDFeFKSNPKLgpEEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCLTSQDCVDLVHLGLREGKTLNEISSRIIDV---CCAPTTEGTGIGC ||..|..||. . | | .| .| .||. .. || ....|.||| ||.|..||..| |..|. ... .| |. . . .... . .||. LavaRslGDl-Wsynaks--geyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskklra DNMSIVVV |..|| Dnvsvivv |
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| Phosphatase | PTC2.AA | Subfamily.PHLPP.PD | 53-250 | 20 | 2.4e-11 | 33.3 | In-house | 37-227 (257) | Show / Hide |
Range on Protein: 53-250 Range on HMM: 37-227/257 Sequence Identity: 20% (43 aa) DHIAFYGIFDGHGGAKVAEYCGNKIVEILQEQKSFHEgNLPRALIDTFINTDVKLLqdpvMKEDHSGCTATSILVSK------SQNLLVCGNAGDSRTVL . | ||..|| .... . ..|.|. . .. | . .... .. || .. .. |..| | . . | | .|.|. ..|| nveavyGlidGdrnselpsllqctmadvlkeevqkdk-neevyianillvshrklG----eaGqklGasallirikedrvdiassftltaanvgkcklvl ATDGNAKALSYDHKPTLA-SEKSRIVAADGFVE-MDRVNGNLALSRAIGDFefKSNPKLGPEeqivtcvPDILEHSLDYDrDEFVILACDGIWDCLTSQD .| || . | .|| | .... ..||| .. .| .| . | . |. | . . | . ||..|| ...|. | .. irnGkplplskvyileiddeelkrikeakaiitednkvnGviestrilGyt--flfPvvlPk-------phvrsvlLteq-dEllilGnkalWevlside CVDLVH |. |. aveavr |
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| Phosphatase | PTC2.AA | Subfamily.PPM1H.PD | 95-170 | 31 | 1.9e-10 | 30.3 | In-house | 141-212 (402) | Show / Hide |
Range on Protein: 95-170 Range on HMM: 141-212/402 Sequence Identity: 31% (24 aa) ALIDTFINTDVKLLQDPVMKEDHSGCTATSILVSksQNLLVCGNAGDSRTVLATDGNAKALSYDHKPtlASEKSRI || . |.. | .. .. ... |||| . || .. | |||||| .| . .. ..|| |. | ..|. |. alesaflemDeqiarereayrikGGCtalvalvl--lgklYvanaGDsRailvrkdeiiplsadftP--eteRqRl |
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| Phosphatase | PTC2.AA | Subfamily.PPM1H.PD | 180-253 | 26 | 7.4e-08 | 21.7 | In-house | 277-353 (402) | Show / Hide |
Range on Protein: 180-253 Range on HMM: 277-353/402 Sequence Identity: 26% (20 aa) DRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSL---DYDRDEFVILACDGIWDCLTSQDCVDLVHLGL |. . .. .| .|| | | . ....||.. | . ..|. .||| ||.|| |. .. .|. | aRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevl |
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| Phosphatase | PTC2.AA | Subfamily.TAB1.PD | 118-240 | 27 | 3.9e-06 | 16.1 | In-house | 137-269 (336) | Show / Hide |
Range on Protein: 118-240 Range on HMM: 137-269/336 Sequence Identity: 27% (36 aa) SGCTATSILVsKSQNLLVcGNAGDSRTVLATDG----NAKALSYDHKPTLASEKSRIVAA---DGFVEMDRVNGNLALSRAIGDFEFKSNPK----LG-P | || |. ..| | | |||| .| . ..| || || | |. . . .. |. |.|||.. | || ... . gGttavvali-lnnkLyv-aNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvlssA EEQIVTCVPDILEHSLDYDRDEFVILACDGIWDCL ||| . | .|..| ||. . | kgePiiatPdingpkdindlegfllLmSdGlykal |
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| Phosphatase | PTC2.AA | Subfamily.TAB1.PD | 38-100 | 31 | 5.4e-06 | 15.7 | In-house | 20-82 (336) | Show / Hide |
Range on Protein: 38-100 Range on HMM: 20-82/336 Sequence Identity: 31% (19 aa) DSHILEPNVLTkSDKDHIAFYGIFDGHGGAKVAEYCGNKIV-EILQEQKSFHEGNLPRALIDTF ..| | .|.. . .| | |..|||. | |.||. ...| |.|. . | .. |..|. edhenedkvfs-rteddiilyavfdGydGekaaefveqrLvaelllgdlseeaeaepkllllqv |
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