PPH2
Species: S.cerevisiae
Alias: PPH2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP2C
Protein domain

Protein domains of PPH2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPH2.AA Family.PPP.PD 51-361 43 5.6e-126 410.3 In-house 28-340 (349) Show / Hide
Range on Protein: 51-361
Range on HMM: 28-340/349
Sequence Identity: 43% (134 aa)

NFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDT-NYL
. .  .|   ..... | . ..  ... .. .|.. . . |.. .|..|...| ..|. |.|.  .. |.|.|||.||||.|||.||.|.| .|...|||
klsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkyl

FMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGS-ANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQV
.|||||||..|||.. .|.|.|..|| |...||||||||....|||||.|. .|| . ......|...|...|..||.|.||.|.||||||....||.| 
FlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqi

RDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDE
..| .|.|.||..||||||||... ||  ..||.||.||.|. |.| ..|.|.|| |||..|.||| . .....||||||||||....|.||...||.| 
rkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdk

NHNRQFLQYDPSV
. .. |..||   
nlklsivqfkpsk

Phosphatase PPH2.AA Subfamily.PPP2C.PD 91-360 77 3.8e-179 583.6 In-house 1-270 (271) Show / Hide
Range on Protein: 91-360
Range on HMM: 1-270/271
Sequence Identity: 77% (210 aa)

LSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQ
|.|..|..||..| ..|. |.|||....|||.|||||||||||||||.||| .||||||||||||||||||||||..|||.||||..|||||||||||||
leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrq

ITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQ
||||||||||||||||.|||||.|||||||.|.||||||.||||||||||.|.|.|..|.|.|.|||||||||||||||||||||||||||||||.|||.
itqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgk

DISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPS
||||.||.||.|.|..||||||||||.|||..|||||||||||||||||||||.|.|......|||.||.
diseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpa

Phosphatase PPH2.AA PP2Ac 91-361 41 7e-150 505.14 SMART 1-321 (321) Show / Hide
Range on Protein: 91-361
Range on HMM: 1-321/321
Sequence Identity: 41% (132 aa)

LSEDDVARLCKMAVDVLQFEENVKPIN----VPVTICGDVHGQFHDLLELF---KIGG-PCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITIL
... ....|| .. ...  |.|. ..      |||.|||.||||.|||.||   ...| |.|.|||.|.|||||||..|.|....|...|..|| ....|
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHESRQIT---QVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSP------MIETIDQVRDLNR----IQEVPHEGPMCDLLWS
|||||.|...   |.||||||| |||.....||.|...|...|..||..|||.| ||||||      .|.|.|. | . |     || |..|.|||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP---------DDRGGWGISP-RGAGFTFGQDISEQFNHTNDLSLIARAHQLVM----EGYSWSHQQ-----NVVTIFSAPNYCYRCGNQAAIMEV----
||         ..  ||.... ||....||.|. ..| ..|.|.|| ||||.|.    .|| . | .      ..|||||||||..|.| ||.|.|    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DENHNRQFLQYDPSV
      |.| . .| |..|  
VIQYKMDKNLKCHFVQFKPQM

Phosphatase PPH2.AA Subfamily.PPP4C.PD 92-357 64 4.6e-140 455.4 In-house 2-267 (271) Show / Hide
Range on Protein: 92-357
Range on HMM: 2-267/271
Sequence Identity: 64% (170 aa)

SEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQI
.|..| .||. | ..|  | ||. .. |||.|||.||||.|||||||.|| .|.|||||.||.||||.|||||   |.|.||||| |||..|||||||||
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

TQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQD
|||||||||||||||||.||.. |..|||....|..|.||||.|||||| |.|.|..| ..| ||||||||.||||||||.|||..||||||. ||.|..
tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsd

ISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQY
||||..||..||.|||||||||| .  ...|.|..||||||||||| |||.|.||. ...|  .  
vveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkif

Phosphatase PPH2.AA Subfamily.PPP6C.PD 91-355 55 1.5e-130 424.2 In-house 1-265 (271) Show / Hide
Range on Protein: 91-355
Range on HMM: 1-265/271
Sequence Identity: 55% (147 aa)

LSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQ
|.|... .||.. .|.|  | ||.|.. |||.|||.||||.||.|||. ||  |||.|.|.||.|||||||.||...|...|..||.|||.|||||||||
lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq

ITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQ
||||||||||||.|||.||.|| .|..|| ....|..|....|.|||||| ..|.||.| ..| ||.||.|..|||.||||.|   | .||||||. ||.
itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgs

DISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFL
 ....|.|.|.|.||.||||||.||. .  ....||..||||||||||| |.|........|.. 
kvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereak

Phosphatase PPH2.AA Group.PPP.PD 51-361 43 5.6e-126 410.3 In-house 28-340 (349) Show / Hide
Range on Protein: 51-361
Range on HMM: 28-340/349
Sequence Identity: 43% (134 aa)

NFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDT-NYL
. .  .|   ..... | . ..  ... .. .|.. . . |.. .|..|...| ..|. |.|.  .. |.|.|||.||||.|||.||.|.| .|...|||
klsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkyl

FMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGS-ANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQV
.|||||||..|||.. .|.|.|..|| |...||||||||....|||||.|. .|| . ......|...|...|..||.|.||.|.|||||| ....||.|
FlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqi

RDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDE
 ..| .|.|.||..||||||||... ||  ..||.||.||.|. |.| ..|.|.|| |||..|.||| . .....||||||||||....|.||...||.|
rkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdk

NHNRQFLQYDPSV
 . .. |..||  
nlklsivqfkpsk

Phosphatase PPH2.AA Subfamily.PPP1C.PD 91-354 48 1.7e-100 325.9 In-house 1-264 (271) Show / Hide
Range on Protein: 91-354
Range on HMM: 1-264/271
Sequence Identity: 48% (129 aa)

LSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQ
|.| .. .||. | ...  .  .  .. |. |.||.|||..||| ||. ||  |..||||.|||||||  |.||.. |.|.|..||... .||||||. .
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

ITQVYGFYDECLRKYgSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGFTFG
|...||||||| |.| . ..||.|.| |. .||.|.||.||||.|||||| .....|.| ..|  .||..| .|||||||||..  ||| . ||  ||||
inriygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfg

QDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQF
.|. |.| . .||.|| ||||.| .|| . .....||.||||||| .  | .|.| |||.   .|
advvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsf

Phosphatase PPH2.AA Subfamily.PPP_Nematode_6.PD 92-356 44 3.6e-95 308.1 In-house 2-267 (272) Show / Hide
Range on Protein: 92-356
Range on HMM: 2-267/272
Sequence Identity: 44% (116 aa)

SEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQI
.|... .|...| .|.. .. .  .. |...|||.|||. ||| ||. ||  ||.||||.||||||| .|.|..  |.| ||..|... .||||||  .|
keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai

TQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDD-RGGWGISPRGAGFTFGQ
 .|||||||. |.| |......| ..|...|.|||| ..|.|.|||||......||.|.|.| .. ..|    |||||||..   ||  . ||.. .||.
nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe

DISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQ
|  ... .. |. |.|||||.| .|| .  ....|||||||.|| .| ||.|.|||.    |    
davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfev

Phosphatase PPH2.AA Subfamily.PPP5C.PD 69-358 34 1.1e-83 270.8 In-house 48-343 (346) Show / Hide
Range on Protein: 69-358
Range on HMM: 48-343/346
Sequence Identity: 34% (103 aa)

KLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVP----VTICGDVHGQFHDLLELFKIGG-PCPDTNYLFMGDYVDRGYYSVE
.  .  .. ... .|.. | . | .  .... ..| ..|. .  .  |..|    .|.|||.||||.|||..|.. | | ..  ||| ||.|||| .|||
eeekitkefvkellelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsve

TVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYgSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPM-IETIDQVRDLNRIQEVPHEGP
..  |...|. ||... . |||||| .. ..||| .|.  || ...| ..||..|...|.. ....|.. .||||      |.|..| ..| .. |.||.
viltllgfkllypnhfflsrGnhesdnmnklyGfegevkaky-tekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegl

MCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEV-DENHNRQFLQYD
...||||||... | . | || |..|| |....| ..|.|.|| |.|.. .|||  .|. ...|.|||||||. ||..|.... ... . .| ... 
llellwsdpqeanGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfe

Phosphatase PPH2.AA Subfamily.PPP3C.PD 91-357 39 1.1e-83 270.8 In-house 1-279 (292) Show / Hide
Range on Protein: 91-357
Range on HMM: 1-279/292
Sequence Identity: 39% (110 aa)

LSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQ
|.|...... ..| ..|. ||..  .. |.|..||.||||.|||.||..||   .|.|||.||||||||.|.|.| || |.|. ||.|. .||||||.|.
leeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrh

ITQVYGFYDECLRKYGsANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGW--------GISPR
.|. . | .|.  ||.  .|...... || .|..||...| .|.|||||| |...|....|.| .|.|. ||.||||||||.. |           |.||
lteyftfkeevkikys-eevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvr

GAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQ------QNVVTIFSAPNYCYRCGNQAAIMEVDENHNrQFLQY
  . ..   . .| ..|||  | |||.   .||   ..        ..|.||||||.    |.||......|.  ..    
GcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl-nirkf

Phosphatase PPH2.AA Subfamily.PPP_Nematode_4.PD 94-359 38 2.1e-80 259.8 In-house 4-269 (271) Show / Hide
Range on Protein: 94-359
Range on HMM: 4-269/271
Sequence Identity: 38% (101 aa)

DDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQ
...  . ..|  ..  |...  |. |. . ||.|.||.|| .||.. |  |.. ..|.|||||||  ..|..  |...|.||..|| .||||||  .. .
eeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnk

VYGFYDECLRKYGSaNVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRG-GWGISPRGAGFTFGQDI
.||||.||  |||  ..|  |   |. .|..||. .|..|.|||||| . ..|..|.  .  |.. | . ||||.|||... .|  | ||...|||... 
kygfyeecvtkyge-elwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgv

SEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDP
|.  .. .. || ||||.|..||     ....|.||.||||| ||.. .||| . .. .. |     
vedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvp

Phosphatase PPH2.AA Subfamily.PPP_Nematode_2.PD 117-356 42 4.7e-77 248.5 In-house 30-276 (281) Show / Hide
Range on Protein: 117-356
Range on HMM: 30-276/281
Sequence Identity: 42% (106 aa)

NVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGS--ANVWKMF
.|||. .|.|||. ||| .| | .  . ..|||.|||||||  |||.|  |.|.| .||. . .||||||  . |  |||.|||| ||.     ||.|. 
clpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffdeclekyndkgekvwlmi

TDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPD--DRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLV
| |...|..||. .|..|.|||.|| .| .... ...|   ||  |  ||||||||.  .| ||..| ||  |.|.. . |.| . |||.|. |||||. 
idafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivvekfcadndldlvvrahqls

ME----GYSWSHQQNVVTIFSAPNYCyRCGNQAAIMEVDENHNRQFLQ
|    |. .  .  .|..||| ||    .|..... ..| .  ||.. 
kemirqghklrangrlvslfsalnyl-smkndssvlkleevktlqfvk

Phosphatase PPH2.AA Subfamily.PPP_Nematode_5.PD 94-359 34 7e-73 234.8 In-house 4-272 (274) Show / Hide
Range on Protein: 94-359
Range on HMM: 4-272/274
Sequence Identity: 34% (92 aa)

DDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQ
.|.  . . . ..|.    .  .. |.||.||.|||..||| .|.  |  |...|||.|||||||  |.| . .| ..|..||... .|||||| ..| .
kdilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkink

VYGFYDECLRKYGsANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQ--EVPHEGPMCDLLWSDPDDRgGWGIS---PRGAGFTF
.|||..|  .|..  ...|.| |.| ..|. | |...|.|.|||.|| ....|... |.. ..|| . ||||.||.     ..     |.    ||.   
lygfkeelkkkrq-eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd-aktfelnkiraisvvf

GQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDP
... .. |..|| |||... |||..  .. .||.|||| |..  | .|.. |..  . .| .  |      
GkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp

Phosphatase PPH2.AA Subfamily.PPP_Nematode_3.PD 146-352 44 2.5e-72 233.5 In-house 93-299 (308) Show / Hide
Range on Protein: 146-352
Range on HMM: 93-299/308
Sequence Identity: 44% (90 aa)

TNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYgSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETI
.|||.||||||| .|.| |. |.|.|..||.....|||||||| . . |||| |. ..| ||.....|   |  .|..|.|..||.|.|||.|  .  ..
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry-saalyeafqlafnvlplcavvnkkilcmhGGiseelldl

DQVRDLNRIQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIM
|.  |.|  ..|  | ..|| |.||| .  |.  |.||||. ||..  ..|... || |. ||||.|..|| .  ....|||||||.|| .  | ||...
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl

EVDENHNR
||..    
svdkklvi

Phosphatase PPH2.AA Subfamily.PPP_Nematode_7.PD 92-350 32 6.5e-59 189.3 In-house 2-285 (296) Show / Hide
Range on Protein: 92-350
Range on HMM: 2-285/296
Sequence Identity: 32% (91 aa)

SEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELF-----------KIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRIT
|. ..  |.... .... |...  |  |||| ||.|||..||  .            |.. .   . ..|.|||||||..|.| .| ..|.|. ||... 
sknellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyi

ILRGNHESRQITQVYGFYDE---CLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNR-IQEVPHEGPMCDLLWSDPDDRGG
.||||||.. |   |.|  |    | |  . .... | . | ..|..||| .||.|.|||.||.|.........| ..|| ..    |||..|| |  . 
llrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvql

WGISP----------RGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENH
 ..           ||  ..|..   |.. . ..|.|| |||| .||. .  .. ..||||||.|    .|. |...|. |   
laavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveang

Phosphatase PPH2.AA Metallophos 118-313 26 2.2e-41 148.57 Pfam 1-124 (124) Show / Hide
Range on Protein: 118-313
Range on HMM: 1-124/124
Sequence Identity: 26% (51 aa)

VPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDL
 ....|||.|||..||..||.|. . ......|.|||||||..| |.. .|...|..||... ..||||........|||| |        |.| |. ..
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW

FDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVM
| . |   |.| ||.| ||..                                                         |   |.. ...|.|. |.
F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase PPH2.AA Subfamily.PPP7C.PD 75-250 31 2.7e-37 118.1 In-house 21-202 (338) Show / Hide
Range on Protein: 75-250
Range on HMM: 21-202/338
Sequence Identity: 31% (57 aa)

INQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINV----PVTICGDVHGQFHDLL-ELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLV
...... .| . . . |    |. . . . .||.  .|.. ..      ||.|||.||...|||  |.| | | .. .|.| ||.||||||| .  |.|.
lddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilf

AMKVRYPHRITILRGNHESRQITQVYGFYDECLRKY--GSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIEtIDQVRD
 . ||. . . |||||   .   |||  |   ||   .... ... |.| ..|...|.|.||. .|||.| . . .. .    
alllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktd-lelldk

Phosphatase PPH2.AA Subfamily.PPP_Nematode_1.PD 100-351 22 4.2e-33 104.7 In-house 10-261 (273) Show / Hide
Range on Protein: 100-351
Range on HMM: 10-261/273
Sequence Identity: 22% (57 aa)

CKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYD
|.....    .. |. .||..||. ... |||...|. |  ..  .||.|. .| | .|.|..  |.  |. ||... ||||..|   .     .. |  
ledalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrlig

ECLRKYGSANVWKMF----TDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRggwgiSPRGAGFTFGQ-DISE
 ..  .| |.        |   .|| |... |......|.|..|   ..|  ..| .   ..    .. . | |       ||   .  ...  |  .  
elrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-----sPvtendidekskivk

QFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHN
 . |.|.. |....| |||  . . ...|..||...     |.... .| .      
ellkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlk

Phosphatase PPH2.AA Subfamily.PPP7C.PD 263-358 34 2.5e-22 68.9 In-house 239-335 (338) Show / Hide
Range on Protein: 263-358
Range on HMM: 239-335/338
Sequence Identity: 34% (33 aa)

MCDLLWSDPDDR-GGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYD
. |.|||||  . | .  . ||.|  || |..... .  .|.|. |.|.  .||| ..|...|.||||| ||     |. | . . .. ....||  
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltprivqyq

Phosphatase PPH2.AA Subfamily.PPP_Nematode_3.PD 92-141 40 1.7e-11 33.8 In-house 2-51 (308) Show / Hide
Range on Protein: 92-141
Range on HMM: 2-51/308
Sequence Identity: 40% (20 aa)

SEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGG
.| ....||  | ...  |.  . ...||||.||.||||.||| |... |
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG

Sequence
Name Sequence Type Origin Length Description Download
PPH2.AA Protein None 377 None Fasta, JSON
PPH2.NA RNA None 1131 None Fasta, JSON
PPH2.AA.PD_91-361 Protein Phosphatase Domain None 271 None Fasta, JSON