PPH3
Species: S.cerevisiae
Alias: PPH3
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP4C
Protein domain

Protein domains of PPH3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPH3.AA Subfamily.PPP7C.PD 3-181 35 2e-40 128.4 In-house 23-207 (338) Show / Hide
Range on Protein: 3-181
Range on HMM: 23-207/338
Sequence Identity: 35% (66 aa)

DLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDT----PVTICGDIHGQLHDLLTLFEKSGG-VEKTRYIFLGDFVDRGFYSLESFLLLLCY
|..|.. ...  | .  . |  .  .... | .  |...| |     ||.|||.||.|.||| .. | |   ..  |.| |||||||  |.|  |.|...
dveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfal

KLRYPDRITLIRGNHETRQITKVYGFYDEVVRKY--GNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSpDMTTVDEIRTIDRKQ
 | ||  . | |||||   .   |||  ||  ||   .... |   .|| .| |...|.. |. ||||.| |.| .. .  |.|..
llvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis-dktdlelldkiersk

Phosphatase PPH3.AA Subfamily.PPP4C.PD 17-286 68 8.70000000001e-158 513.5 In-house 1-270 (271) Show / Hide
Range on Protein: 17-286
Range on HMM: 1-270/271
Sequence Identity: 68% (186 aa)

IPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQ
| ||.| .|| ...|.|..|.||..||.|||.|||||||..|||.||. .| |..|.|.||||||||||||.|.|||||..|.||||||||||||||.||
ikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrq

ITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGK
||.|||||||..||||...|||||.||||||||.|||...||||||||||...|.||||.|||||||||||..||||||||||...|..||||||.|||.
itqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgs

REVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAV
..|.|| |.|..|||.||||||||||| .|.  ..|||||||||||||||||.|..|..|.....||||.
dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa

Phosphatase PPH3.AA PP2Ac 17-287 41 1.6e-145 490.68 SMART 1-321 (321) Show / Hide
Range on Protein: 17-287
Range on HMM: 1-321/321
Sequence Identity: 41% (133 aa)

IPEETVFRLCLNSQELLMNEGNVTQVD----TPVTICGDIHGQLHDLLTLF---EKSG-GVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLI
.... ...||  ..|... | |.  |.     |||.|||||||..||| ||   .| | ... |.| ||||.||||..|.|  .||.|||..||....| 
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHETRQIT---KVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSP------DMTTVDEIRTIDR----KQEVPHEGAMCDLLWS
|||||.|...   ..||||||. |||.. ..| ...|.|....|.|.||| |.|.||||||      . .| |.|| |||     || |..| |||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP---------EDVDTWSLSP-RGAGFLFGKREVDQFLEKNNVELIARAHQLVM----EGYKEMFDG-----GLVTVWSAPNYCYRCGNVAAVLKI----
||          .|. |. .. ||... ||.. ||.|..||| .|| ||||.|.    .||. ..|.      |.|..||||||..|.| |||.|.    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DDDLNREYTIFEAVQ
      |..|.  .  |....
VIQYKMDKNLKCHFVQFKPQM

Phosphatase PPH3.AA Subfamily.PPP6C.PD 18-287 61 3.5e-138 449.2 In-house 2-271 (271) Show / Hide
Range on Protein: 18-287
Range on HMM: 2-271/271
Sequence Identity: 61% (166 aa)

PEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQI
||. . .||   ..||..|.||  | .|||.|||||||..||. || ..| | .|.|.|||||||||.||||.| .||. |..|||||||.|||||.|||
penelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi

TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKR
|.|||||||...||||.|.|.||..||| |...|||.....|||||||||..|.|.||.|.| ||.||.||.|||.|||||||.||..||||||.|||..
tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgsk

EVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQ
 ...|.. ||..||.||||||.||.| |||  ||||||||||||||||.|..|...|. .||  .|.||.
vtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereaklfkavp

Phosphatase PPH3.AA Subfamily.PPP2C.PD 19-284 58 6.8e-123 399.1 In-house 3-268 (271) Show / Hide
Range on Protein: 19-284
Range on HMM: 3-268/271
Sequence Identity: 58% (155 aa)

EETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQIT
|| | .|| ...|.| .| || .| .|||.|||.|||.|||| ||   | . .| |.|.||.||||.||.|.  ||.. |.||..|||..|||||.||||
eeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqit

KVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKRE
.|||||||..|||||.|||.|  ..|||| | |...| |||.|||||| ..|.|.||..|| |||||||.|||||||||.||..||||||. |||   ..
qvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgkdi

VDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFE
| ..|...|..||||||||||.   |  .||..||||||||||| ||.|..||.|....  |.   
seefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfd

Phosphatase PPH3.AA Family.PPP.PD 5-289 47 2.4e-122 398.4 In-house 56-342 (349) Show / Hide
Range on Protein: 5-289
Range on HMM: 56-342/349
Sequence Identity: 47% (135 aa)

DKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKT-RYIFLGDFVDRGFYSLESFLLLLCYKLRYPD
.... .... |......|..|. . .|||..| |...|..|.|.|||||||..|||.||...|  ... .|.||||.|||| .|.| .|||...||.||.
kelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllyps

RITLIRGNHETRQITKVYGFYDEVVRKYGN-SNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDT
|..|.|||||.|...||||||.|| .|| . ........|||..|.| |.|...|.||||||||..|..|.||.|.|..|.|.||..|||||||||... 
rffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkg

WSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQ
|. ..||.||.||.  |..||.|||..|| |||..|.|||. .... |||..||||||....| |||||.|..|. . ..|.... .
wkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhk

Phosphatase PPH3.AA Group.PPP.PD 5-289 47 2.4e-122 398.4 In-house 56-342 (349) Show / Hide
Range on Protein: 5-289
Range on HMM: 56-342/349
Sequence Identity: 47% (135 aa)

DKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKT-RYIFLGDFVDRGFYSLESFLLLLCYKLRYPD
.... .... |......|..|. . .|||..| |...|..|.|.|||||||..|||.||...|  ... .|.||||.|||| .|.| .|||...||.||.
kelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllyps

RITLIRGNHETRQITKVYGFYDEVVRKYGN-SNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDT
|..|.|||||.|...||||||.|| .|| . ........|||..|.| |.|...|.||||||||..|..|.||.|.|..|.|.||..|||||||||... 
rffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkg

WSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQ
|. ..||.||.||.  |..||.|||..|| |||..|.|||. .... |||..||||||....| |||||.|..|. . ..|.... .
wkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhk

Phosphatase PPH3.AA Subfamily.PPP1C.PD 19-285 45 3.1e-96 311.9 In-house 3-269 (271) Show / Hide
Range on Protein: 19-285
Range on HMM: 3-269/271
Sequence Identity: 45% (122 aa)

EETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQIT
|... .|||...|.....  . ....|. |.|||||| .||| ||||.|   ...|.||||.||||  |||. .|||.||..||... |.|||||. .|.
eaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecasin

KVYGFYDEVVRKYgNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPE-DVDTWSLSPRGAGFLFGKR
..||||||. |.| | ..|.   ..|. | . ||... |||||||||||......|| | |  .||..| .||||||||. .| .|. . ||  | ||..
riygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgad

EVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEA
 |..||.|....|| ||||.| .||. . .  |||..|||||| .  |..||...|..|  ...|...
vvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkp

Phosphatase PPH3.AA Subfamily.PPP_Nematode_6.PD 18-283 43 1.7e-89 289.5 In-house 2-268 (272) Show / Hide
Range on Protein: 18-283
Range on HMM: 2-268/272
Sequence Identity: 43% (114 aa)

PEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQI
||....|. .........  . .|..|...|||||||  ||| ||.|.|  ... |.||||.|||| .|||  ||||.||...|... |.|||||. .| 
keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai

TKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPED-VDTWSLSPRGAGFLFGK
.|||||||| |.| .....    |||..| | |.. . |.|.|||||. ....|..|.. | .. ..|    ||||||||. |. |. . ||..  ||. 
nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe

REVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIF
.| ..||| ...|.|||||.| .||. . .  |||..|||.|| .| |||.|.|..|   ....   
davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevl

Phosphatase PPH3.AA Subfamily.PPP5C.PD 5-287 42 3.7e-86 279.0 In-house 58-346 (346) Show / Hide
Range on Protein: 5-287
Range on HMM: 58-346/346
Sequence Identity: 42% (123 aa)

DKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTP----VTICGDIHGQLHDLLTLFEKSGGV-EKTRYIFLGDFVDRGFYSLESFLLLLCYKL
....  ... |....  .... |...||| ..  ......|    .|.||||||| .||| .||. | . |.  |.| ||||||| .|.||.||..|| |
kellelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkl

RYPDRITLIRGNHETRQITKVYGFYDEVVRKYgNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGL-SPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPE
|... | |||||. .. |.||| .||  || ...|     |||..| |. .||.... ||||| | |  |.|..|.|||.. |.||....||||||..  
lypnhfflsrGnhesdnmnklyGfegevkaky-tekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpq

DVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKI-DDDLNREYTIFEAVQ
  | | || |. ||    ..||..||.||| |.|.. .|||. . || |.||.|||||| . || .|.... .|||. ... ||||.   
eanGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfeave

Phosphatase PPH3.AA Subfamily.PPP_Nematode_4.PD 26-278 42 1.6e-83 270.0 In-house 10-262 (271) Show / Hide
Range on Protein: 26-278
Range on HMM: 10-262/271
Sequence Identity: 42% (105 aa)

CLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYD
........| .......|. . ||.|.| .||  ||.  | | .....||||.||||  ..| ..||.|.|.||.||| |.|||||. .. |.||||.|.
ireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnkkygfye

EVVRKYGNsNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPE-DVDTWSLSPRGAGFLFGKREVDQFLE
| |||. ..|    ..|. | . |.| . ..|.||||||.....||.| | .  | .. | .||||.||. .|  |  | ||....|||  |..   . .
ecvtkyge-elwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgvvedvck

KNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNR
|.|| ||||.|..||. .    |.||.|.||||    | |||||.|..|.    
slevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenlei

Phosphatase PPH3.AA Subfamily.PPP_Nematode_5.PD 34-281 42 3e-79 255.7 In-house 18-268 (274) Show / Hide
Range on Protein: 34-281
Range on HMM: 18-268/274
Sequence Identity: 42% (104 aa)

MNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGn
. .|..|.||.|||||||.||| .|.. |   |..|.||||.||||  |||  |||...|..|| .. |.||||| ..| |.|||..|. .|.. .....
kplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeelkkkrq-

SNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQE--VPHEGAMCDLLWSDPE-DVDTWSLS-PRGAGFLFGKREVDQFLEKNNVE
   .|| .|.| |.... |.|.|||.||.. ..|..... . .     .|| . ||||.||| | .|  |   |.   .|||.|||..|.| ...|| ||
eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldid

LIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYT
|... |||. .||  ||||.||| |. .  |..||.....|.  ..      
livrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfv

Phosphatase PPH3.AA Subfamily.PPP3C.PD 19-275 42 1.3e-78 254.0 In-house 3-272 (292) Show / Hide
Range on Protein: 19-275
Range on HMM: 3-272/292
Sequence Identity: 42% (111 aa)

EETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQIT
||.. ..  .. .|| .| .. .|..|.|..|||||| .||| ||| .|  ..|.|.||||.|||| .|.|  | |.. |. ||.|. |.|||||.|..|
eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt

KVYGFYDEVVRKYGNsNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPE-DV------DTW-SLSPRGA
. . | .||  ||.. .|.  ..| || | | |..|.  .||||||||.....|.|...|| .|.|. |..||||||||  |...   |.||  .... .
eyftfkeevkikyse-evyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGc

GFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFD------GGLVTVWSAPNYCYRCGNVAAVLKIDDD
 | .||.||..  | |||.   .||.   .        |.|..|||||.    | |||||....       
syfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyenn

Phosphatase PPH3.AA Subfamily.PPP_Nematode_2.PD 42-275 44 2.1e-72 233.3 In-house 29-269 (281) Show / Hide
Range on Protein: 42-275
Range on HMM: 29-269/281
Sequence Identity: 44% (104 aa)

VDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNS--NVWRY
|||. .|.|||  ||| .|   .   ...|.||||.||||  |.|  ||||.|| .||| . |.|||||  . |  |||.||   ||..    ||..  .
eclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffdeclekyndkgekvwlm

CCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVD--TWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQL
 |..| | |.| . ..|.|||.|| .  ...|  |.|   ||  |  |||||||||  .|||| ||  | |..  |..| ..|...|. |||||. |   
iidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivvekfcadndldlvvrahql

VME----GYKEMFDGGLVTVWSAPNYCyRCGNVAAVLKIDDD
 |.|  ..| ||...|| ||    .| ..|||..        
skemirqghklrangrlvslfsalnyl-smkndssvlkleev

Phosphatase PPH3.AA Subfamily.PPP_Nematode_3.PD 71-284 41 2.3e-72 233.7 In-house 92-305 (308) Show / Hide
Range on Protein: 71-284
Range on HMM: 92-305/308
Sequence Identity: 41% (88 aa)

KTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNsNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTT
. .|.||||.|||| .|.|  .||...||.|||...|.|||||.| . . |||| || ..| . ...     .|  | | |..|. |.|.|||.| ... 
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa-alyeafqlafnvlplcavvnkkilcmhGGiseelld

VDEIRTIDRKQEVPHEGAMCDLLWSDPE-DVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAV
.... ...|  ..|  | ..|| |.||. .|...  |.||||..||.. |..||.| ...|. ||||.|..||. . |  |||..|||.|| .  |.|||
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

LKIDDDLNREYTIFE
|..|..|   .|.. 
lsvdkklvisltvlr

Phosphatase PPH3.AA Subfamily.PPP_Nematode_7.PD 21-276 34 6.1e-56 179.5 In-house 5-285 (296) Show / Hide
Range on Protein: 21-276
Range on HMM: 5-285/296
Sequence Identity: 34% (96 aa)

TVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLF----------EKSG-GVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIR
.. |. . .||. .| .. .. .|||| |||||| .||  .           .||. .  .....||||.|||| .|.||.. .|. || .. |.|||||
ellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyillr

GNHETRQITKVYGFYDEVVR---KYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRK-QEVPHEGAMCDLLWSDPEDVDTWSL
|. |   |.|  |..    |    ...    ||| .. | |.. . |.|||||.|| ......|. |.|  .|| ..    |||..|| ||..   .   
GnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqllaa

SP----------RGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDL
        ||  . |..  |... .|.|..|| |||| . ||.| . |  |.|..|||.|    .|  ||||.. .     
vsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveang

Phosphatase PPH3.AA Metallophos 44-239 26 5.7e-41 147.22 Pfam 1-124 (124) Show / Hide
Range on Protein: 44-239
Range on HMM: 1-124/124
Sequence Identity: 26% (52 aa)

TPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEV
 ....|||||||..||..|||.    . . .||.||.|||| .|.| ..||.|||..||... ..||||. ......|||| |        |.| .....
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW

FDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVM
| .. |  ...  |.|.||..                                                         |.. |.| ...|.|. |.
F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase PPH3.AA Subfamily.PPP_Nematode_1.PD 33-283 24 5.1e-37 117.5 In-house 16-267 (273) Show / Hide
Range on Protein: 33-283
Range on HMM: 16-267/273
Sequence Identity: 24% (64 aa)

LMNEGNVTQ-VDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKY
...|    . ....||..||| ..  ||| ... .|   . ...|||...| | .|||  |.||| |  || .. ..||..||  .     .. |.  ..
iaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrf

GNSNVWRYCC----EVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSdpeDVDTwsLSPRGAGFLFGK-REVDQFLEKN
 .|| ||       ..   | . |..| ....|..|.|. .   ... ...|..   .. .  .. .    |.|    ||   . ...| . | . |   
pdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfl---didi--PsPvtendidekskivkellkat

NVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIF
..... |....| |||.  ..  |.|..||...     |  .|| || ||  ..  .
dmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfkli

Phosphatase PPH3.AA Subfamily.PPP7C.PD 189-279 34 5.4e-17 51.4 In-house 239-330 (338) Show / Hide
Range on Protein: 189-279
Range on HMM: 239-330/338
Sequence Identity: 34% (31 aa)

MCDLLWSDPEDVD-TWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNRE
. |.|||||.  .  .. . ||.|  ||    ...|.| |.||. |.|.  .|||. . .  ..|..|| ||     |  | .|. .||.. 
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltpr

Phosphatase PPH3.AA Subfamily.PPP_Nematode_3.PD 20-67 41 1.9e-11 33.6 In-house 4-51 (308) Show / Hide
Range on Protein: 20-67
Range on HMM: 4-51/308
Sequence Identity: 41% (20 aa)

ETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSG
. . .||. ..||. .|    ....||||.|||||| .|||.|..  |
kelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG

Sequence
Name Sequence Type Origin Length Description Download
PPH3.AA Protein None 308 None Fasta, JSON
PPH3.NA RNA None 924 None Fasta, JSON
PPH3.AA.PD_17-287 Protein Phosphatase Domain None 271 None Fasta, JSON