Gene Sit4
Sit4
Species: S.cerevisiae
Alias: Sit4
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Sit4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | Sit4.AA | Family.PPP.PD | 8-295 | 47 | 5.2e-123 | 400.6 | In-house | 57-344 (349) | Show / Hide |
Range on Protein: 8-295 Range on HMM: 57-344/349 Sequence Identity: 47% (138 aa) EWLETIKKCQALTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAK | .|..|. . |...|...|.|..||||..|.|.. |..|.||||||||||.|||.||.. | |. .|.|||||||||..|.|...||..||..|| . elveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsr ITLVRGNHESRQITQVYGFYEECLNKYGS-TTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAW ..|.|||||||....|||||||. .|| . .........||. |.|||.||.||||||||||||. ||||| . | .|.|.|| . |||||||.... | ffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkgw QVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKdVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFSAVPDDYI . ..||.|..||... ..| . |.|.|| |||..|.||..... .| .||..||||||....| |.|.|||..|. ....| ...... kpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrk-lvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr |
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| Phosphatase | Sit4.AA | Subfamily.PPP6C.PD | 19-291 | 69 | 5.1e-158 | 514.2 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 19-291 Range on HMM: 1-271/271 Sequence Identity: 69% (190 aa) LTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPDDiNYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESR |.|||.|.||..|..||.||||.|||..||||||||||||.||.|||||.| .||. .|.||||.||||||||||||.|..||.|||..|||.||||||| lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdt-syvflgdfvdrgyysletftrlltlkakypdritllrgnhesr QITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFG |||||||||.|||||||....||||..|||.||.|||||...|||||||||....||||||..||||.||.|.|.||.||||..||.|.|||||||.||| qitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfg SKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKdVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFSAVP |||..||.|.| |.||.||||||.||.||.| || .|||||||||||||||.||....... | ..|.|.||| skvtkefvhinnlklicrahqlveeglkymfdek-lvtvwsapnycyrcgniasilaledaeereaklfkavp |
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| Phosphatase | Sit4.AA | Subfamily.PPP4C.PD | 20-290 | 67 | 8.4e-146 | 474.2 | In-house | 2-270 (271) | Show / Hide |
Range on Protein: 20-290 Range on HMM: 2-270/271 Sequence Identity: 67% (183 aa) TENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPdDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQ .|.|.|.||. ..|.|.||||.| |..||||||||||||.||||||. .| | . ||.||||.||||.||.||| ||..|||.||..|||.|||||||| keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvp-etnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrq ITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFGS ||||||||.|||.||||..||.||..|||.|.|||||||||.||||||||.|..||.||.. | ||||||| ..|||||||...|.|.|||||||.|||| itqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgs KVAREFNHVNGLNLIARAHQLVMEGFKYHFPEkDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFSAV .|. .||. |...||.|||||||||.|.|| | |.||||||||||||||||.....||.|. ||||.|. dvveqfneandielicrahqlvmegyklhfne-kvltvwsapnycyrcgnvaaileldeeldkdfkifeaa |
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| Phosphatase | Sit4.AA | PP2Ac | 19-291 | 42 | 5.2e-140 | 472.34 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 19-291
Range on HMM: 1-321/321
Sequence Identity: 42% (135 aa)
LTENEMKQLCEMVKELLMEESNIQPVQ----TPVTVCGDIHGQFHDLLELF---RTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLV
....| .|||..|||... |.| .|. ||||||||||||.|||.|| . .| .| . || |||||||||..|.|. .|| |.|..|| ...|
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
RGNHESRQIT---QVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSP------EIRMLDQIRVLSR----AQEVPHEGGFSDLLWS
|||||.|... |.||||.|| .||.. .||.....|. . |.|.|..||||.|||||| .| ||.||.. | .|| |..| |||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP---------DNVEAWQVSP-RGAGWLFGSKVAREFNHVNGLNLIARAHQLVM----EGFKYHFPE----KDVVTVWSAPNYCYRCGNVASVMKV----
|| ..|. || .. ||.. || .| .|| . |.|.|| ||||.|. .|... . . . ..|..||||||..|.| |.||||
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------DEDLEPTFKIFSAVP
|..| ..|. | ...
VIQYKMDKNLKCHFVQFKPQM
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| Phosphatase | Sit4.AA | Subfamily.PPP2C.PD | 19-288 | 61 | 4.6e-132 | 429.2 | In-house | 1-268 (271) | Show / Hide |
Range on Protein: 19-288 Range on HMM: 1-268/271 Sequence Identity: 61% (166 aa) LTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPdDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESR |.|.|.|.|||. ||.| .|||...|..|||||||.|||||||||||| | | | ||.|.||||||||||.|| |||..|||.|. .||..||||||| leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggksp-dtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesr QITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFG |||||||||.||| |||...|||| ..||.| |.|..|..|.|.||||||.| ||.|| | | ||||||| . ||||||||. | .||||||. || qitqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfg SKVAREFNHVNGLNLIARAHQLVMEGFKYHFpEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFS ....|||. |||.|..|||||||||... ...|||..||||||||||| |.....|..|. .| | kdiseefnktngltlvsrahqlvmegynwsh-drnvvtifsapnycyrcgnqaailelddelkysflqfd |
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| Phosphatase | Sit4.AA | Group.PPP.PD | 8-295 | 47 | 5.2e-123 | 400.6 | In-house | 57-344 (349) | Show / Hide |
Range on Protein: 8-295 Range on HMM: 57-344/349 Sequence Identity: 47% (138 aa) EWLETIKKCQALTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAK | .|..|. . |...|...|.|..||||..|.|.. |..|.||||||||||.|||.||.. | |. .|.|||||||||..|.|...||..||..|| . elveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsr ITLVRGNHESRQITQVYGFYEECLNKYGS-TTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAW ..|.|||||||....|||||||. .|| . .........||. |.|||.||.||||||||||||. ||||| . | .|.|.|| . |||||||.... | ffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkgw QVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFPEKdVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFSAVPDDYI . ..||.|..||... ..| . |.|.|| |||..|.||..... .| .||..||||||....| |.|.|||..|. ....| ...... kpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrk-lvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr |
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| Phosphatase | Sit4.AA | Subfamily.PPP1C.PD | 19-288 | 46 | 3.4e-96 | 311.8 | In-house | 1-268 (271) | Show / Hide |
Range on Protein: 19-288 Range on HMM: 1-268/271 Sequence Identity: 46% (126 aa) LTENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTaGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESR |.|.|...||. .|..... . ...|. ..||||||..||| || . |||| . ||.||||||||| |||| .||...|.||| ..|.|||||. . lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfek-ggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnheca QITQVYGFYEECLNKYgSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDN-VEAWQVSPRGAGWLF |...||||.|| .| . .|| ..|. | .|||.| ||.||||||||... |.||| ..| .||..| ..||||||||. |. |. . || . || sinriygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftf GSKVAREFNHVNGLNLIARAHQLVMEGFKYhFPEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIFS ..| ..| . . |.|| ||||.| .|... | ....||..|||||| . |...||.|||.| .|.|. gadvvekflkkhdldlivrahqvvedgyef-fakrqlvtlfsapnycgefdnagavmsvdeellcsfqilk |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_6.PD | 20-287 | 46 | 2.8e-94 | 305.1 | In-house | 2-268 (272) | Show / Hide |
Range on Protein: 20-287 Range on HMM: 2-268/272 Sequence Identity: 46% (124 aa) TENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTaGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQ .|.|...|.|..|....... . |..|..||||||||. ||| || ||||.| ||.||||||||| .|||. .||.. |||.| .. |.||||| . keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdk-ggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnhecea ITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDN-VEAWQVSPRGAGWLFG | .|||||.|. ..| ||.... .||. | |.|.. |.|||.|||||.... |||.| |.|.. ..| |||||||.| |. |. . ||.. ||. inrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfG SKVAREFNHVNGLNLIARAHQLVMEGFKYhFPEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIF .. ... . ..|.|||||.| .|... | || .||..|||.||. | |.||||||.|. .|... edavkkllekldidlvarahqvvqdGyef-faekklvtifsaphycgqfdnaaavmkvdeklvvsfevl |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_4.PD | 20-285 | 41 | 3.1e-81 | 262.5 | In-house | 2-265 (271) | Show / Hide |
Range on Protein: 20-285 Range on HMM: 2-265/271 Sequence Identity: 41% (109 aa) TENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAGGFPDDiNYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQ |..|.... ........|... ...|. | ||.|.||.|| .|| | |.. ..||||||||| ..|.. ||.|||..|. .| |.||||| . tkeeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpee-klvflgdyvdrgpqgievlillfclkiryrdrivllrgnheias ITQVYGFYEECLNKYGSTtVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDN-VEAWQVSPRGAGWLFG . ..||||||| ||| .| ..|. | ..|.| |.||.|||||||. ||..| .| .. | ||||.|||| || |. | ||....|| . vnkkygfyeecvtkygee-lwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfg SKVAREFNHVNGLNLIARAHQLVMEGFKYhFPEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFK | . . ...|| ||||.|..|.. . . ..||.|.||||| |.|.|.||.|| ... kgvvedvckslevdliirahqvvqdgyev-lsgrklitvfsvpnycaqfknaaavlkldenleislv |
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| Phosphatase | Sit4.AA | Subfamily.PPP3C.PD | 20-280 | 41 | 1.1e-77 | 251.1 | In-house | 2-273 (292) | Show / Hide |
Range on Protein: 20-280 Range on HMM: 2-273/292 Sequence Identity: 41% (113 aa) TENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTaGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQ .|... .. |.. .|| .|... |..|.||.|||||||.|||.|| || |....|.||||||||||.|.|. |..||..|| .. |.|||||.|. eeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfev-gGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrh ITQVYGFYEECLNKYGsTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDN-------VEAW-QVSPR .|. . | ||. ||. .|.. ... || | |||....| |||||||||||. ||.|. | | .|.|. | . |||||||. |.. . |.|| lteyftfkeevkikys-eevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvr GAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHF-----PEKDVVTVWSAPNYCYRCGNVASVMKVDEDL .... | . || . | | | |||. .|.. . . ..|..|||||. | |.|.|.... GcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennv |
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| Phosphatase | Sit4.AA | Subfamily.PPP5C.PD | 9-291 | 39 | 9e-76 | 244.8 | In-house | 60-346 (346) | Show / Hide |
Range on Protein: 9-291 Range on HMM: 60-346/346 Sequence Identity: 39% (112 aa) WLETIKKCQALTENEMKQLCEMVKELLMEESNIQPVQT----PVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKY ||..|| ..| . . .. ..|||| ... . ... .||||||||||.|||..|. | .. |.| ||.|||| .|.|..|...|. || . llelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfklly PAKITLVRGNHESRQITQVYGFYEECLNKYGStTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSP-EIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNV . | |||||| .. ..||| .|. .|| . .| . .||..| || .|. |.| ||||| . ||..| ..| ..|.|| . .||||||.. . . pnhfflsrGnhesdnmnklyGfegevkakyte-kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqea EAWQVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFpEKDVVTVWSAPNYCYRCGNVASVMKV-DEDLEPTFKIFSAVP | || | || |...| . |.|.|| |.|.. .||.. . . ..||.|||||| . || ........||.|.|| | ||. nGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGyeveh-dGklitvfsapnycdqmgnkgafitlrgddlkpkfktfeave |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_5.PD | 21-284 | 38 | 8.9e-73 | 234.5 | In-house | 3-267 (274) | Show / Hide |
Range on Protein: 21-284 Range on HMM: 3-267/274 Sequence Identity: 38% (101 aa) ENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAgGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQI .... .. | .|. | . . |..|.|..||||||..||| .| | . ...|.||||||||| ||| ||..||..|| |. |.||||| ..| dkdilevlekikstlkplaalleveapitivGdihGqlddllrifnav-GaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkki TQVYGFYEECLNKYGsTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQE--VPHEGGFSDLLWSDPDN-VEAWQVS-PRGAGWL ..|||.|| .|.. ...| .|| |.| |... .|||.|||.||... ||... |.. ..|| ||||.||.. .. .. |. .|| |. nklygfkeelkkkrq-eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvv FGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFpEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTF .. . ...|| |||... ||... | .| .|||.||||. . |...|..|.. || .| fGkkevddllkkldidlivrahevseeGyaflf-dkrlvtvfsapyysgedtnlgavvvvskslelsf |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_3.PD | 76-288 | 43 | 8.7e-72 | 231.8 | In-house | 94-305 (308) | Show / Hide |
Range on Protein: 76-288 Range on HMM: 94-305/308 Sequence Identity: 43% (92 aa) NYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVYGFYEECLNKYgSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLD .|.||||||||| .|.| .||..||..|| |..|.||||||| . . ||||.|. ..| |..... ..| | |.|...||||.|||.| |. |.| kylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry-saalyeafqlafnvlplcavvnkkilcmhGGiseelldlk QIRVLSRAQEVPHEGGFSDLLWSDPDN-VEAWQVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYhFPEKDVVTVWSAPNYCYRCGNVASVM . .| | ..| | .|| |.|||. |. .. |.|||| .||.| .||.. |.|. ||||.|..|... | .. .||..|||.|| . |.|.|.. qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyef-fadrklvtifsapsycGqldniaavl KVDEDLEPTFKIFS ||..| ..... svdkklvisltvlr |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_2.PD | 35-279 | 42 | 4.3e-69 | 222.4 | In-house | 17-269 (281) | Show / Hide |
Range on Protein: 35-279 Range on HMM: 17-269/281 Sequence Identity: 42% (106 aa) LMEESNIQPV---QTPVTVCGDIHGQFHDLLELFRTAGGfPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVYGFYEECL ..| | . | |||| .|.|||. ||| .| . . | .|.||||||||| |.|. ||...| .|| .. |.||||| . | |||..||| flefsallrvdeeclpvtvvadlhgqsidllriflinea-pgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffdecl NKYGS--TTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVE--AWQVSPRGAGWLFGSKVAREFNH .||. . ||.. . |. | |||.| .|.||.|||.|| .. |..| . | || ||||||||.. | | .| || . |. | .| . |. ekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivvekfca VNGLNLIARAHQLVME----GFKYHFPEKdVVTVWSAPNYCyRCGNVASVMKVDED |.|. |||||. | | |... . .|...|| || .|.||.|..| dndldlvvrahqlskemirqghklrangr-lvslfsalnyl-smkndssvlkleev |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_7.PD | 20-280 | 35 | 1e-58 | 188.6 | In-house | 2-285 (296) | Show / Hide |
Range on Protein: 20-280 Range on HMM: 2-285/296 Sequence Identity: 35% (101 aa) TENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELF---------RTAGGFP-DDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKIT ..||. .|...||||. .| .. . .|||. ||||||..|| . . ... ..|||||||||..|.| .|.. ||. || |. sknellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyi LVRGNHESRQITQVYGFYEECLN---KYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRA-QEVPHEGGFSDLLWSDPDNVEA |.|||||.. | |.| || | | ...... .|| |. |||.. ||||||||.||.. |..|. ..| .|| .. |||..|| .|.. llrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvql ---WQ-------VSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYhFPEKDVVTVWSAPNYCYRCGNVASVMKVDEDL . || . |. . ... . ..|.|| |||| .||||. | .| ..|..|||.| .| .|.||. . laavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkf-fadkkLltifsaprymnesdnsgavlkveang |
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| Phosphatase | Sit4.AA | Metallophos | 46-242 | 26 | 5.5e-41 | 147.27 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 46-242 Range on HMM: 1-124/124 Sequence Identity: 26% (53 aa) TPVTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVYGFYEECLNKYGSTTVWKYCCQ ....|||||||..|| ... .. .. ..||.|||||||..|.|.. ||.|.|..|| .. .|||||........|||| | ..| .... MRILHCGDIHGQYDDL-NRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWW VFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVM .| .. || ..|.||||.||.. | ||. ...|.|. |. WF-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP |
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| Phosphatase | Sit4.AA | Subfamily.PPP7C.PD | 9-177 | 38 | 2.8e-37 | 118.1 | In-house | 27-203 (338) | Show / Hide |
Range on Protein: 9-177 Range on HMM: 27-203/338 Sequence Identity: 38% (66 aa) WLETIKKCQALTENEMKQLCEMVKELLMEESNIQPVQTP----VTVCGDIHGQFHDLLELFRTAGGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKY ||..|. . | . . .. |. | . ||. |.| ||||||.||...||| .. | . .|.| ||.|||| |.|.|..| . || .. lleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvy PAKITLVRGNHESRQITQVYGFYEECLNKY--GSTTVWKYCCQVFDFLTLAAIIDGKILCVHGGLSPE--IRMLDQI | ||||| . ||| | .|| .. . . .|| .| ||..|| ||| ||||.| . . .||.| pkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktdlelldki |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_1.PD | 27-287 | 24 | 2.3e-34 | 108.8 | In-house | 9-267 (273) | Show / Hide |
Range on Protein: 27-287
Range on HMM: 9-267/273
Sequence Identity: 24% (64 aa)
LCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAgGFPDDINYIFLGDYVDRGYYSLETFTLLMCLKVKYPAKITLVRGNHESRQITQVYGF
| | ... | | .. ....|||.||| ... |||...... |.| . ..|||. .| | .|||. .|.| |. || ....||..| . ..
lledalkiaeetslleyieadvtviGdirsryadlldilklt-GwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrl
YEECLNKYGSTTVWKYCC----QVFDFLTLAAIIDGKILCVHGGLSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDnveawQVSPRGAGWLFGS-KV
| .. . |. .. | .||... |.|.|..|.|. |. ... . | ... .. . | | . || . ... |. .|
igelrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldid-----iPsPvtendidekski
AREFNHVNGLNLIARAHQLVMEGFKYHFPEKdVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFKIF
.... |....| ||... . .. ..|..||...| |. .| || ||| .
vkellkatdmsvmirsnsvvreGylftlknr-litltsatklqkdynnrGvvlsidkdlkvtfkli
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| Phosphatase | Sit4.AA | Subfamily.PPP7C.PD | 194-285 | 34 | 1.7e-15 | 46.5 | In-house | 241-332 (338) | Show / Hide |
Range on Protein: 194-285 Range on HMM: 241-332/338 Sequence Identity: 34% (31 aa) DLLWSDPDNVEA-WQVSPRGAGWLFGSKVAREFNHVNGLNLIARAHQLVMEGFKYHFpEKDVVTVWSAPNYCYRCGNVASVMKVDEDLEPTFK |.||||| . | . . ||.| ||. |.... . .|.|. |.|. .||... .| |.|..|| || | . .|. .||.|. dilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefth-nkkvltifsasnyyeeGsnrGayvklgkdltpriv |
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| Phosphatase | Sit4.AA | Subfamily.PPP_Nematode_3.PD | 20-72 | 43 | 7.7e-13 | 38.2 | In-house | 2-53 (308) | Show / Hide |
Range on Protein: 20-72 Range on HMM: 2-53/308 Sequence Identity: 43% (23 aa) TENEMKQLCEMVKELLMEESNIQPVQTPVTVCGDIHGQFHDLLELFRTAgGFP .|.|. .|| .||. .| ...|||..|||||||.||| |. |.| kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldln-Gwp |
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