Spur_PTPN1
Species: S.purpuratus
Alias: Spur_hmm39988, Spur_PTPN1, hmm16457
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N1
Protein domain

Protein domains of Spur_PTPN1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Spur_PTPN1.AA PTPc 3-286 28 1.6e-87 297.99 SMART 1-308 (308) Show / Hide
Range on Protein: 3-286
Range on HMM: 1-308/308
Sequence Identity: 28% (98 aa)

SLEEEFKEYEERKLWP---------TIFWDIHKE--SSLYELPTTDAKDPINKGLNRYR-DIHPYNHTRIRLER--------GDVRYINASLIEAPLAKR
...|||..... . |.         ..   ...|  .               .  |||. || .| |||..| .        ..  ||||. |. .  ..
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENRE---------------MDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPK

KYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVEN--------HQQKCADYFPRGQDNGNTDELLCEDTLLKVTYLRQERHH-YYIVRTLLLEDLVT-
.||.|||||  |. .||.|||.| ...|.||.|..|.         . ||..|.|.        ..  .   ..|| .. | .  .|..||. ...  . 
RYICTQGPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-------PMTYG--HITVTCKSEEKCPDDYTMRTFEVTNTGCN

-------QQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDN-----------------VGPPVIHCSAGVGRSGTLCLVDTCLVQIEKKGNT
       ..|... |.||| | |..|| || .||.|.. || . |   |                  ||.|.|||||.||.||.|..|... |||.    
CKYSMACSETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----

SGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILEGSK
  .|. . .  || .|.|..|| .|..| | .|||  |
--VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK

Phosphatase Spur_PTPN1.AA Subfamily.N1.PD 17-286 62 4.6e-141 460.2 In-house 2-268 (268) Show / Hide
Range on Protein: 17-286
Range on HMM: 2-268/268
Sequence Identity: 62% (170 aa)

WPTIFWDIHKESSLYELPTTDAKDPINKGLNRYRDIHPYNHTRIRLERGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNF
...|...|.|||. .||.|..||.| |.|||||||..||.|.||.|||.||.||||||.|.. |||.||||||||..|..|||||||||.|.|.||||..
ykeilleidkeskekeletreaklpenrglnryrdvspydhsrikleradvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkv

VENHQQKCADYFPRGQDNGntdELLCEDTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDNVG
||..|.|||.|.|......   |||.|.| |||.....||..|..||.| |||| ||.|.||||||||.|.||.||.||||||.||..||.||||...||
vEknqikCaqywpqeeeea---ellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvg

PPVIHCSAGVGRSGTLCLVDTCLVQIEKKGNTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILEGSK
|.|||||||.||||||.|||||||.|||.|.....|..|.||..|.||.|||||..||||||.|||||.|
pavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiailegak

Phosphatase Spur_PTPN1.AA Y_phosphatase 43-283 37 7.5e-85 293.0 Pfam 1-243 (243) Show / Hide
Range on Protein: 43-283
Range on HMM: 1-243/243
Sequence Identity: 37% (95 aa)

NKGLNRYRDIHPYNHTRIRLE----RGDVRYINASLIEAP-LAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQ-QK-CADYFPRGQDNG
||  |||.|| .| |||..|     ..|  ||||. |. |   ...||.||||.  |. .||.|||.| ...|.||.|..|. . .| |. |.|    | 
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPD---NK

NTDELLCEDTLLKVTYLRQERHHYYIVRTLLLEDLVT--QQTKEILHFHYTRWSDFSVPQS-PAAFLQFLHHVRRSGSLVDNV-GPPVIHCSAGVGRSGT
  ... .    ..||  . | ...|.|||. ...  .  |.|... |.||| | |..|| | | ..|.|.. || . . .|.  .|.|.|||||.||.||
EGQPMTYG--DFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGT

LCLVDTCLVQIEKKGNTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
.|..|... |.|..|     |. . .  ||. |.|..|| .|..| | .|||
FCAIDIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Spur_PTPN1.AA Subfamily.N3.PD 33-282 38 5e-64 207.3 In-house 16-257 (261) Show / Hide
Range on Protein: 33-282
Range on HMM: 16-257/261
Sequence Identity: 38% (97 aa)

LPTTDAKDPINKGLNRYRDIHPYNHTRIRLERGDVRYINASLIEAPL----AKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYF
| .. |. | |   |||||| ||..||..|. ... ||||. ..  .    .  .|| |||||..|. .||||||||.|. |.|| . ||. ..||  |.
laisaarkpenlaknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyW

PRGQDNgntdellCEDTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLvdNVGPPVIHCSAGVGR
|. .|.       .| . ..|.  ...... |..| |.|.|  |.. ..||.. |. |.| .||...| ||.|...||.  |   .| |.|||||.||.|
Petede-------lefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsg--keePvvvhCsaGigr

SGTLCLVDTCLVQIEKKGNTSGLDVRKQlldMRRYRHGLIQTWQQLRFSYCAIL
 | |..|.|  ||.. .   ||. ..   ||  |  |.|| .| .|   |||  
tGvlilletalalieaaepvypldivrt---mrdqramlvqtvsqykfvCeail

Phosphatase Spur_PTPN1.AA Subfamily.N13.PD 36-283 38 1.7e-62 202.6 In-house 19-256 (259) Show / Hide
Range on Protein: 36-283
Range on HMM: 19-256/259
Sequence Identity: 38% (95 aa)

TDAKDPINKGLNRYRDIHPYNHTRIRLERGDVrYINASLIEAPLAKR--KYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQD
. .|.  ||  ||||.. ||..||..|.     |||||||..|. .   .||..||||  ||  ||||||||... |.|. . .|. . |||.|  ..  
evgkkkenkdknryrnvlPydetrvklgdegg-yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerkn

ngntdELLCEDTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRsgsLVDNVGPPVIHCSAGVGRSGTLC
   . |     |.|. |...... . ||.| ..|. .....|. |.....| | .||.|.| ..||. .||.   | .. || |.|||||.||||.|  .
-----kklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrl---lqtdagPivvhcsaGiGrsGvli

LVDTCLVQIEKKGntsGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
|. |  ||..     .||.. . ..|. |.|..|| .|  | | ||||  
tidvvlglierdk---efdvkeivrklreqrqgvvqtkdqyifvykaile

Phosphatase Spur_PTPN1.AA Subfamily.RB.PD 34-282 33 6.7e-62 200.5 In-house 17-257 (261) Show / Hide
Range on Protein: 34-282
Range on HMM: 17-257/261
Sequence Identity: 33% (84 aa)

PTTDAKDPINKGLNRYRDIHPYNHTRIRL----ERGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFP
... |....|.  ||.. | ||.|.|..|    .. |  ||||. |.    .|.|| |||||  || .||.||||. |..|.|| . ||. ..|| .|.|
avkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWP

RGQDngntdelLCEDTLLKVTYLRQERHHYYIVRTLLLEDlvTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDNVGPPVIHCSAGVGRS
  ..        .    .||| | ..... ...|.. .|    ...... ..|.| |.|..||..... |.|...||.. .   . .||.||||||||.|
adee-------pvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRt

GTLCLVDTCLVQIEKkgnTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAIL
|   .|. | .||.   .  .||   . ..|. |  |.|| .|  | . ..| 
Gtfialdrllqaiee---ndyvdvfgvvaelReeRnllvqtekqyifihecll

Phosphatase Spur_PTPN1.AA Subfamily.R_Anemone_1.PD 34-283 35 6.2e-61 197.6 In-house 16-255 (258) Show / Hide
Range on Protein: 34-283
Range on HMM: 16-255/258
Sequence Identity: 35% (91 aa)

PTTDAKDPINKGLNRYRDIHPYNHTRIRLER----GDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFP
.  |. . ||  ||| || ...|.|. ||.     .  ||||| ..|   .|..|.||.||..||  ||.|||.... .|.||.|..|....||  |.| 
ekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwP

RgqdngNTdELLCEdtlLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSgSLVDNvGPPVIHCSAGVGRS
     .| |  .|   |.|.  ..|    ||.|||.|.   .....|. ..|.| |.| .|||  .| |.....|..| || ..  | |.||||||||.|
d-----st-ekyge---lrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-slaga-rpvvvhCsaGvgRt

GTLCLVDTCLVQIEKKgntSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
. . .|. | |. |.     .|... .  .|. |  ..|| .|  | . |.|| 
Gaflvidamleqakke---kvvDifnyvkairedrphmvqtkeqyvfihlavle

Phosphatase Spur_PTPN1.AA Subfamily.N6.PD 25-281 33 1.9e-60 195.9 In-house 22-290 (295) Show / Hide
Range on Protein: 25-281
Range on HMM: 22-290/295
Sequence Identity: 33% (91 aa)

HKESSLYELPTTDAKDPINKGLNRYRDIHPYNHTRIRLERG-----DVRYINASLI----------EAPLAK---RKYILTQGPLTRTVCHFWQMVWEQD
|. |   .  .... . ||  |||..| |..|||. |. |     .  ||||. |          |.. ..   ..|| |||.|. ||  ||.|||...|
qkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqen

SRAIIMLNNFVENHQQKCADYFPRGQDNGNTDEllcedtlLKVTYLRQERHHYYIVRTLLLEDL-VTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHV
| |.|. . ||  ..||| |.|  ... .| .       ..|| .. . .. |..|.....     ....|| ..|.. | | .||..| ..|.||..|.
srvivmttkevergknkCarYWPdeetkketGv-------itvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledv

RRSGSLVDNVGPPVIHCSAGVGRSGTLCLVDTCLVQIEKKGNTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAI
.  . . . || |.|||||.|| ||. ..|. | .||..|    .|..|.. |.|..| ||.|| .|..| | |. 
nkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykav

Phosphatase Spur_PTPN1.AA Subfamily.N_Choan_1.PD 34-283 34 2.6e-59 192.1 In-house 17-259 (262) Show / Hide
Range on Protein: 34-283
Range on HMM: 17-259/262
Sequence Identity: 34% (86 aa)

PTTDAKDPINKGLNRYRDIHPYNHTRIRL----ERGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFP
..| .| . |.  |||..|  |..||...    |  .  ||||. ...   ...|| ||||.  .. .||||||||. .||.|. ..|. . ||  |.| 
tataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWP

RGQDngntdELLCEDtlLKVTYLRQERHHYYIVRTLLLeDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDNvGPPVIHCSAGVGRS
..      ||   |  ..|. |..|... || |.. | .  . .|.|. ...|| | |  ||......|.| .|..  .   .  | ||||||||||.||
dens-----elklgd--vtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvihCsaGvGrt

GTLCLVDTCLVQIEKKGNTsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
   .|. . ..|.| ..  |||.  . ..|. |  ..||  | .| | |.|.  
GtyialDrlvkaveekaea--ldvkavvaelrkernlmvqtlvqyefvykavld

Phosphatase Spur_PTPN1.AA Subfamily.N12.PD 32-283 31 5.6e-59 190.8 In-house 21-267 (270) Show / Hide
Range on Protein: 32-283
Range on HMM: 21-267/270
Sequence Identity: 31% (81 aa)

ELPTTDAKDPINKGLNRYRDIHPYNHTRIRLER----GDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADY
. .|. .. . |.  |||.|| ||...|. |..     .  ||||..|. .  | .|| .||||..|.  ||.|.||.. . ..|. . ||....||. |
vysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCery

FPRGQDNGntdellCEDTLLKVTYLRQERHH-YYIVRTLLLEDLvtQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSlvDNVGPPVIHCSAGV
.|  ...       .|   ..||  .... .  ...||| .|    ......  |||| | |  ||.|.   |.....||.  ...  | |.||||||||
Wpeegeee------lefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGv

GRSGTLCLVDTCLVQIEKKGNTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
 ||.. .|    .....  .. ||| . .|..|. |. |.|| .| .. | |..|  
GrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae

Phosphatase Spur_PTPN1.AA Subfamily.R_Anemone_2.PD 35-283 32 6.9e-58 187.5 In-house 19-259 (262) Show / Hide
Range on Protein: 35-283
Range on HMM: 19-259/262
Sequence Identity: 32% (83 aa)

TTDAKDPINKGLNRYRDIHPYNHTRIRLERGD----VRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPR
.. | .|.||  ||| .| .|..||..|.  .      ||||. |.   .|..|| ||.||..|.  ||.|||||.|. |.|| ..|. ..|.. |.|  
lksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPs

GQDNgNTDEllcedtlLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSlVDNVGPPVIHCSAGVGRSG
. . . ..       |.|.   . .  .|..|.. ..   .......  |||| |.| .||.|.| .|... .|..      ..|| |.|||||||| |.
kgsr-sygk-------lvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqq-esgagpivvhcsaGvGrtG

TLCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
 . ||. | .|.. .    .|| . .  .|. |  ..|| .|  | | ..|| 
vfiavdillerikaeal---vdvfqtvkqlreqrnlmvqtkdqyefiydvlle

Phosphatase Spur_PTPN1.AA Subfamily.R_Sponge_2.PD 33-283 34 1.7e-57 186.2 In-house 15-259 (262) Show / Hide
Range on Protein: 33-283
Range on HMM: 15-259/262
Sequence Identity: 34% (86 aa)

LPTTDAKDPINKGLNRYRDIHPYNHTRIRLER---GDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFP
...|| ..|.| ||...| ||...|.||.     |  ||||| ...   .  || |||||. ||  || ||||. .. |.|| |.|| ..||| |.|. .
fslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWP

RGQDNGNTdelLCEDtllKVTYLRQERHHYYIVRTLLLEDLVT-QQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDNvGPPVIHCSAGVGR
|.  .   . .    |||   .|.   ||.|.| | .  . ...... .||.. |.. .||.. ...|.....|.|.     | .. ...||.||||.||
ekvdeeve---ygkf---kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgn-kaitvvCsdgvgr

SGTLCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
 . .|. | .... ..   .|| . | ..|  | ||.|. .|  | . |.||   
tGtfialdsvlerlkaeee---idvfevlktlrtkriglvqdaaqYvfihdalle

Phosphatase Spur_PTPN1.AA Subfamily.N_Choan_2.PD 43-283 34 4.2e-56 181.3 In-house 21-263 (266) Show / Hide
Range on Protein: 43-283
Range on HMM: 21-263/266
Sequence Identity: 34% (87 aa)

NKGLNRYRDIHPYNHTRIRLERGD----VRYINASLIE-APLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRgqdnGNT
|| ||||.|| |  .||.|||. .      ||||  .. .  .|.||| ..|||  |. .||.|.||. ..||.|. ...|. ..||. |.|      . 
nkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa----epk

DELLCEDTLLKVTYLRQERHHYYIVRTLLLEDlvTQQTKEILHFHYTRWSDFSVPQSPA------AFLQFLHHVRRSGSLVDNVGPPVIHCSAGVGRSGT
... ..|  .||. | .|... ||.. | ||    ..|... ||.|. | | .||...         |. |..|||. . .|. .| ..||||||||.||
ekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGt

LCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
| ..|...  .|....   .|| . . ..|..|  |.|. .| .. | |..|
liaiDiavrlLeetkk---vdvlaiieelRkdRmalvqhpeqyellykavve

Phosphatase Spur_PTPN1.AA Subfamily.N9.PD 37-283 36 7.9e-56 180.8 In-house 20-272 (275) Show / Hide
Range on Protein: 37-283
Range on HMM: 20-272/275
Sequence Identity: 36% (92 aa)

DAKDPINKGLNRYRDIHPYNHTRIRLERGD----VRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQ
.| . |   ||| |.  |..||. |.. |      ||||. ..    |. .|.||||| .||  ||.|||||. . |.|   .||. . ||.|.| ....
asklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywplee

DNgntdelLCEDTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGS-LVDNV---------GPP-VIH
        | . |.|. . .| .. | ||.| ...  |...... || .. | |. ||.| |..|..|..||.  . .|...||| |.|||||.||.||.
es------saefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvh

CSAGVGRSGTLCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
. .| || ..|..|.   .||.. .  .|  |   ||| .|  | | |.||           
csaGiGrtGtfitldiclarleevgt---vdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase Spur_PTPN1.AA Subfamily.N14.PD 36-282 35 5.6e-55 177.8 In-house 19-271 (275) Show / Hide
Range on Protein: 36-282
Range on HMM: 19-271/275
Sequence Identity: 35% (91 aa)

TDAKDPINKGLNRYRDIHPYNHTRIRLER---GDVRYINASLIEAPLA--KRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPR
. || | |.  ||..|. ||...|..|      .  ||||| |.....  .|.|| .||||  ||. ||||||||. . |.|| .  |. ..|.  |.|.
staklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPk

GQDNGNTDELlcedTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVR----RSGSLV---DNVGPP-VIHC
 ... .| |        |||   .|  . .| ..| |. | ... ....|. || |.|  ||. .  ||.||..|.    .. | |.. || ..||||||
leskkktvef----gkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhC

SAGVGRSGTLCLVDTCLVQIEKkgnTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAIL
||.| | |.|  .  .|.      .|..| |  .|. |  |.||  | .| | ...    
saGvGrtGvlilsdlliatleh---neeidikkvlarLrkqrmllvqtlaqykfvykvli

Phosphatase Spur_PTPN1.AA Subfamily.N5_RR.PD 43-282 29 1e-53 173.7 In-house 23-261 (265) Show / Hide
Range on Protein: 43-282
Range on HMM: 23-261/265
Sequence Identity: 29% (73 aa)

NKGLNRYRDIHPYNHTRIRLE-----RGDVRYINASLIEAPLAKRK-YILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNGN
..  |||..| | ...|. ||       |  ||||  |  .  . | |. |||||. |.  ||.|....... |.|| .. |...|||| |||  .|   
sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyei

TDEllceDTLLKVTYLRQERHHYYIVRTLLLEDLVTqQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDNV-GPPVIHCSAGVGRSGTLCLV
...     . ....     ... | ||.|.|. |    .... |. || | |  .|... ..|.....|..| .  ..  .||.|||||.|| |    ..
ser----ygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiai

DTCLVQIEKkgnTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAIL
 .. |...   .. .|| |   ..|  | |..|| .| .. . |.  
siavrqlre---eivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase Spur_PTPN1.AA Subfamily.RG.PD 31-283 33 2.8e-53 172.3 In-house 15-261 (264) Show / Hide
Range on Protein: 31-283
Range on HMM: 15-261/264
Sequence Identity: 33% (86 aa)

YELPTTDAKDPINKGLNRYRDIHPYNHTRIRLER--G--DVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCAD
..... .|.. ||  ||. .| .....|..|.   |  .  ||||| |.    ...|| |||||. |.  ||.|.||.... |.|| ...|...... |.
kdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedv

YFPRGQDNGNTDEllcedtlLKVTYLRQERHHYYIVRTLLLEDLVTQQTKE--ILHFHYTRWSDFSVPQSPAAFLQFLHHVrrSGSLVDNVGPPVIHCSA
|. ..  ....       ||||.|..|.. .|.||...|..  ... ||  . ..|||.| | ..|.| . .| | ..   . ....|| |.|.||||||
yWPkkdeplelea-------lkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke--eaankeeaGPivvhdsa

GVGRSGTLCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
.||.. .|| | |.||. .    .| . |  .|  | ||..|  | .| | |.||    
Gvgragtyialdtllqqlekeea---vnvyqvlklirakRpglvtteEqyvfiydalle

Phosphatase Spur_PTPN1.AA Subfamily.R_Ecdysozoa.PD 37-283 31 1.6e-50 163.1 In-house 21-266 (269) Show / Hide
Range on Protein: 37-283
Range on HMM: 21-266/269
Sequence Identity: 31% (79 aa)

DAKDPINKGLNRYRDIHPYNHTRIRLER----GDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQkCADYFPRGq
..   |.  |||.||.....||..|..     |  ||||| |..   |.|.|  |.|.  |.  ||.|..||..  |.|| ||. .. || |.|      
vsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWpie-

dngntDELLCEdtLLKVTYLRQERHHYYIVRTLLLEDL---VTQQTKEILHFHYTRWS-DFSVPQSPAAFLQFLHHVR---RSGSLVDNVGPPVIHCSAG
  ||   .   . |.. ..| |..|| |.| .      . ....... ..|| |  |. ||... .|.....||   .  .|.   .| |.|||||||||
-----devqyg--dilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaG

VGRSGTLCLVDTCLVQIEKKgntSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
|..  .|  | |...      .|. .   ..|. |  |.| ..|  | | |...    
vgrsgifvaldlllqqlkae---dkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase Spur_PTPN1.AA Subfamily.RA.PD 38-283 33 1.2e-49 160.4 In-house 22-263 (266) Show / Hide
Range on Protein: 38-283
Range on HMM: 22-263/266
Sequence Identity: 33% (85 aa)

AKDPINKGLNRYRDIHPYNHTRIRLER--G--DVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPrgqD
|. . ||  ||. .| ||...|. |    |  .  ||||| |.    | |.| .|||...||  ||.|.|||.| .|.|| .. | ...||| |.|   |
ankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywp---d

NGNTDellceDTLLKVTYLRQERHHYYIVRTLLLEDL----VTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVDNvGPPVIHCSAGVGRS
.|           ..|.   ..    | || .|...|      .... .  ||.| | .. || ..   |..|..|..      |  ||.||||||||.|
eGlvt-----yGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsan-hpivvhcsaGvGrt

GTLCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
|.. .|. | ... ..    ||| . .  .|  |  ..|| .|  | | ..|| 
Gtfivldavlervkaerk---ldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase Spur_PTPN1.AA Subfamily.RK.PD 38-283 30 1.5e-49 159.9 In-house 24-264 (267) Show / Hide
Range on Protein: 38-283
Range on HMM: 24-264/267
Sequence Identity: 30% (76 aa)

AKDPINKGLNRYRDIHPYNHTRIRLER---GDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNF-VENHQQKCADYFPrgqD
|| . |.  ||. || .|......|      .  ||||.||..    ...| |||||  ||  ||..|..... .|.||... ||. . ||  |.|   .
akkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWP---e

NGNTdellcEDTLLKVTYLRQERHHYYIVRTLLLED--LVTQQTKEILHFHYTRWSDF-SVPQSPAAFLQFLHHVRRSGSLvDNVGPPVIHCSAGVGRSG
....     .   .||.... | .  ..||.. .|      ....|. .|....|...  ||.|  ..|.....| .| .  .. |.|.||.|| |||||
dtev-----rygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-eeeGrivvhClaGaGrsG

TLCLVDTCLVQIEKKGNtsgLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
 . .|. |  ||..|    .|| .   ..| ..  ...| .| .| | .||| 
tfiaidivlemieregv---vdvfnavktlrnrkvnmveteeqykfvydvile

Phosphatase Spur_PTPN1.AA Subfamily.N23.PD 58-283 30 4.6e-46 148.7 In-house 117-347 (350) Show / Hide
Range on Protein: 58-283
Range on HMM: 117-347/350
Sequence Identity: 30% (70 aa)

TRIRLE-----RGDVRYINASLIEAPLA-KRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNGNTDELlcedtlLKVTY
.|. |.          ||||. ..   .   ..| ||||.. |.  ||.||||| |. |.|| . ||. ..||. |.|  ... |. .|.|.  ...  .
nrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgd------lrvsl

LRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSG-----SLV--DNVGPPVIHCSAGVGRSGTLCLVDTCLVQIEK
..| |.| |.   ... ... |.|.| ||.. ||.||  .|.||. |.        . .  .   | ..||||||||.||.|.| . . .....      
kslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelta

KGNTSglDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
.. . .  .|. |.  .|. ..|...| |.||       
gngii--niprvvrrlrqqRkymvqkkvilkklyeavle

Phosphatase Spur_PTPN1.AA Subfamily.RN.PD 37-283 33 1.5e-45 146.8 In-house 21-261 (264) Show / Hide
Range on Protein: 37-283
Range on HMM: 21-261/264
Sequence Identity: 33% (84 aa)

DAKDPINKGLNRYRDIHPYNHTRIRLERG----DVRYINASLIEA-PLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPrg
|| . |   ||.... ||.|.|..|..     .  ||||| |      .  || |||||. |...|||||||| .  |..| .  |.  ..|.|.|   |
vakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywp--

qDNGNTDELLCEDTLLKVtYLRqerHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSgsLVDNVGPPVIHCSAGVGRSGT
.|.    . |  |.   ..     . |.||.. | .| |..|. .  ||.  | . .|| |. ..|.|   | .|        | |.|||.|.||.|. .
-deGsevyhiyevhlvse-hiw---cddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnks--yrGrscpivvhcsdGaGrtGv

LCLVDTCLVQIEKkGnTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
|.|  | .. | |    .|.   |  .|  |.||..| .|..| . |. |  
yilidlvlerllk-G-vkeidiaatlehlrdqrpglvktkdqfefaltavae

Phosphatase Spur_PTPN1.AA Subfamily.N_Nematode_1.PD 42-279 29 5.7e-41 131.8 In-house 25-258 (265) Show / Hide
Range on Protein: 42-279
Range on HMM: 25-258/265
Sequence Identity: 29% (70 aa)

INKGLNRYRDIHPYNHTRIRL--ERGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNGNTDE
... |||.|.   ...|..|  |     || |  . .|   ...| .|.|| .|. .|| ||  .   ||.|| ...|. ..|||.|||  ... .. . 
qeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefk

LLCEDTLL--KVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSgslvdnVGPPVIHCSAGVGRSGTLCLVDT
  .   .  ....  .|...  |  | |  .   ..|... |...| | |  ||.   | |..|..|| |       || |.|||||.||.||.  ..  
ekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs------kgPivvhCsaGiGrtGtivaiey

CLVQIEKKGNTSglDVRKQLLDMRRYRHGLIQTWQQLRFSYC
| .. .  . .  |. | . ..|  |.  ||| .|  | .  
ildkllegkqie--dmeklvkkireqrnysiqtdaqylfvhr

Phosphatase Spur_PTPN1.AA Subfamily.N20.PD 38-283 34 1.6e-40 130.6 In-house 21-254 (257) Show / Hide
Range on Protein: 38-283
Range on HMM: 21-254/257
Sequence Identity: 34% (84 aa)

AKDPINKGLNRYRDIHPYNHTRIRLERGDvRYINASLIEAPLAK--RKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNg
..| |.  |||||| ||. ||. | .    ||||| |    .     || |||||  |.  ||||| |..|  | |.   .|    ||  |.|    .  
gnqpsnreknryrdilpydstrvplgksk-dyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkk-

nTDELlcedTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSgslvDNVGPPVIHCSAGVGRSGTLCLV
  ||      ..|     .  .|.|.| . . .  |  .. . ....|.| |.  | |  .|...... |.|       || |.|||||.||.| .  ||
-plel----khfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarks----hltgpmvvhcsagigrtgvflcv

DTCLVQIEKKGNTSGLDVRKQlldMRRYRHGLIQTWQQLRFSYCAILE
  .. | |. .   .|.  |   ||  | |..|| .| .| |  .|| 
dvvfcaivkncsfnimdivaq---mreqrsgmvqtkeqyhfcydivle

Phosphatase Spur_PTPN1.AA Subfamily.N_Nematode_4.PD 43-283 27 1.3e-39 127.5 In-house 26-261 (264) Show / Hide
Range on Protein: 43-283
Range on HMM: 26-261/264
Sequence Identity: 27% (67 aa)

NKGLNRYRDIHPYNHTRIRLERG--DVRYINASLIEAPlAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNGNTdel
|. .|||.||   ..||. |.    |  || || .  |  | .|| ||||| .|.  || ||...   ...|| ...|. ..||| |.|  ...  .   
nsdknryadilcidetrvvlknrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvk---

lCEDTLLKVTYLRQERHHYYIVRTLLLEDLV---TQQT--KEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRsgslVDNVGPPVIHCSAGVGRSGTLCLV
 . .  ....  ..|     |...| .          .    . |.....| |   |. .|. ....|.      .. .|.|.||||||||. ||  .| 
-fGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk----kkkekPivvhcsaGvGrtatlvGi

DTCLVQIEKKGNTSGLDVRKQlldMRRYRHGLIQTWQQLRFSYCAILE
. ..|  ...   ||. ..   .|  | . .|.  |  | .  ..|  
dyatirirenseievldivre---lramrlkavqshlqflfllvvlie

Phosphatase Spur_PTPN1.AA Subfamily.N_Nematode_6.PD 43-283 29 1.7e-39 127.0 In-house 24-250 (253) Show / Hide
Range on Protein: 43-283
Range on HMM: 24-250/253
Sequence Identity: 29% (69 aa)

NKGLNRYRDIHPYNHTRIRLERGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNGNTDELLC
.| .|||..|. .. .|..|.  .  || |.|..    .|..| ||.||  |. .||.|.  . .  |.|| ..||. ..|.|.|..    . .    ||
fkdrnrytniqCcdagrlkladdedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkitklc

edtllKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRsgslvdNVGPPVIHCSAGVGRSGTLCLVDTCLVQI
     .|. . ..     .||.|.     ...   . |.|.  | |  ||.|  . |..|  |...  | |.|||||||| ||| |. . |  . .    
-----tvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkk------dkkPivvhCsaGvGrtGtlaliliileal

EKKgntSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
   .|.. |  .|. |   .||  |  . .  .||      
rlp---dfqgvkdllvklreerfravqtevqylyalrcvle

Phosphatase Spur_PTPN1.AA Subfamily.RC.PD 68-283 27 1.2e-37 120.9 In-house 74-285 (288) Show / Hide
Range on Protein: 68-283
Range on HMM: 74-285/288
Sequence Identity: 27% (61 aa)

RYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFprgqDNGNTDellCEDtlLKVTYLRQERHHYYIVRTLLL
.||||| |..    .||| .||||  ||  ||.|..|.  . |.|| .  | ...|||.|.    ..|.       |  ..|    ...   ||.| | |
kyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw----eeGkra---yGd--vevdlkdtdkssdyilrklel

EDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQF-------LHHVRRSGSLVD-NVGPPVIHCSAGVGRSGTLCLVDTCLVQIEKKgntSGLDVRKQLLD
 .   ....|. .. || ||.  .|. |  .|..       | . |.| .  .   .| ..||..|..|.|. . ... |  .| ..|| . .  .|. |
vnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleae---ekvdvfqvvkk

MRRYRHGLIQTWQQLRFSYCAILE
 ..... .|  . | .. |     
lrkarplmvsveeqyillydvlve

Phosphatase Spur_PTPN1.AA Subfamily.R_Nematode_2.PD 40-276 27 2e-37 120.2 In-house 26-251 (261) Show / Hide
Range on Protein: 40-276
Range on HMM: 26-251/261
Sequence Identity: 27% (66 aa)

DPINKGLNRYRDIHPYNHTRIRLERGDVR-YINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGqdngNTD
..|  .|| |.   ..|...    . |  | |  .. .  ....| |||||. |.  || ||  ..   |.|| ..||....||..|||      ....|
aylpkdkhRypdvPCkpetavevivdgkrvpihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfple----tsq

ELLCEDTLLKVTYLRQERHHYYIVRTLLLEDLVT-QQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSlvdnvgPPVIHCSAGVGRSGTLCLVDT
  .   .|..  ..  ..   .|||  ||     .|. . |. |..|.|  ||.| |   . |. |..|        | |.|||||.||....  ..   
kldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek------PivvhCsaGiGRtmafigtey

CLVQIEKkgnTSGLDVRKQLLDMRRYRHGLIQTWQQLRF
 ..|.      . . ..| ..| .|   ||| .|| .  
larevea---dptieltealkelrehRwkgiqtesqlyw

Phosphatase Spur_PTPN1.AA Subfamily.R_Nematode_3.PD 48-283 27 1.3e-35 114.3 In-house 28-264 (267) Show / Hide
Range on Protein: 48-283
Range on HMM: 28-264/267
Sequence Identity: 27% (69 aa)

RYRDIHPYNHTRIRLER----GDVRYINASLIEAPlAKRKYILTQGPL--------TRTVCHFWQMVWEQDSRAIIMLNNFVE---NHQQKCADYFPRGQ
|. ..  . .||. |.         .|.|...| |  . | ||||.|.          |.  ||.|. .... ...|| .|||....||. |.|  .|  
rrvevpllektrvvLkgygkrfkddfihAnvvecp-nglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekv

DNgntdELLCEDTLLKVTYLRQERHHYYIVRTLLLeDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQFLHHVRRSGSLVdnvgppVIHCSAGVGRSGTL
   ||  |.  .| |   .| ..    ||| .  .  .... . | .|. |.. ..|..|  .|... |. | . |      |.|||.|..||.||  ..
dg----elkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksktpv------vVHCsdGisRsatl

CLVDTCLVQIEKKGNtsGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAILE
     | |. .   ||... . ..|. |.| ||| ..| |.   ||.    
aaielgyqliikskg--kldllslikelrkqRagaiqtelelafvilgilk

Phosphatase Spur_PTPN1.AA PTPc_motif 177-283 35 1.5e-33 118.66 SMART 1-92 (92) Show / Hide
Range on Protein: 177-283
Range on HMM: 1-92/92
Sequence Identity: 35% (40 aa)

EILHFHYTRWSDF-----SVPQSPAAFLQFLHHVRRSGSLVDNVGPPVIHCSAGVGRSGTLCLVDTCLVQIEKKGNTSGLDVRKQLLDMRRYRHGLIQTW
.. |.||| | |.     .||    ..|.|..|||          |.|.|||||.||.||.|..|... |         .|. . .  || .|.|..|| 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQTE

QQLRFSYCAILE
.| .| | .|||
EQYIFCYRCILE

Phosphatase Spur_PTPN1.AA Subfamily.N_Nematode_5.PD 43-282 26 6.2e-31 98.8 In-house 25-254 (258) Show / Hide
Range on Protein: 43-282
Range on HMM: 25-254/258
Sequence Identity: 26% (64 aa)

NKGLNRYRDIHPYNHTRIRLERGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCaDYFP-RGQDNGNTDELL
|.  ||. |.  ...||..|. .|. ||||| |. . ...|.|||| ||. |.  ||.|| ..   ....| .  | ..... ..|| . .|  |.....
nlkknrskdvkilDetrVkltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdylnlgkmf

CEDTllKVTYLRQERhHYYIVRTLlLEDLVTQqtKEILHFHYTRWSDFSVPQSPAAFLQ-FLHHVRrSGSLVDNvGPPVIHCSAGVGRSGTLCLVDTCLV
 . .  ||.   .|. . | | .|  |.   .    . . |.| | . .||.. .. ..  ...|  |. ..|  | |.....|.||.||. |...   |
innr--kvevkedek-keytvevl-pegcses--vfakvyhlttWkkkkvPdkvkkvikraiekvl-skkqgkn-apvvvvsdlGlgRagtflllsvaie

QIEKKgntSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYCAIL
....   . ... . |  .|  | | ... .|  . | |.| 
qlnng---kepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase Spur_PTPN1.AA Subfamily.N_Nematode_eak.PD 47-210 30 2e-22 71.1 In-house 30-187 (281) Show / Hide
Range on Protein: 47-210
Range on HMM: 30-187/281
Sequence Identity: 30% (51 aa)

NRYRDIHPYNHTRIRLE---RGDVRYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPrgqDNGntDELL--
||  .| |...  .||    .    ||||||.| .   ||||||  .    |  ||||| || | ||..| . ||.. .||||   |..  ..|     |
nrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfp---dkt--evlkyG

CEDTLLKVTYLRQERHHYyivrtLLLEDLVTQQTKEILHFHYTRWSDFSVPQSpAAFLQFLHHVRRSGS
   |   ....  ..      ||.  . ..|...||...  |.....|.    || . . ..  |    
ildverkeyavkrnilet-----rllilrkGnethrvlhykvfGwtettlpky-edflalrkvmkevGv

Phosphatase Spur_PTPN1.AA Subfamily.N_Nematode_egg.PD 32-279 23 1.5e-18 58.4 In-house 15-250 (257) Show / Hide
Range on Protein: 32-279
Range on HMM: 15-250/257
Sequence Identity: 23% (55 aa)

ELPTTDAKDPINKGLNRYRDIHPYNHTRIRLE--RGDV--RYINASLIEAPLAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENhqQKCADY
| . | | .  ..   | . .|  . .|..||  ||     .| |  ..      ..||.| ||  ||  ||.||.... .|.||.  .|.  ..|  |.
eislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyy

FPRGQDngntDELLCEDTLLKVTYLRQERHHYYIVRTLLLEDlVTQQtKEILHFHYTRWsDFSVPQSPAAFLQFLHHVRRSGSlvdnvgPPVIHCSAGVG
|. ..    . |      |... |. ...   . |   |   |  . .| |.  . .. |.|. | ..|.         | |...  || ...||  ...
wpkaes----eslvtvpGslrienlkvdskadplfrvtklkl-vGgd-deelflehwqg-dvnylsdvysplrvlrklrnlsk------pvvvqdilGvs

RSGTLCLVDTCLVQIEKkGNTSGLDVRKQLLDMRRYRHGLIQTWQQLRFSYC
 |... . | .    |..    .|. |.  ...  .| |             
kaatlvaieiallsllr-Gpitkslvlravvflrlrrrlsvesvllylfvyr

Phosphatase Spur_PTPN1.AA Subfamily.N_Fungi_PTP1.PD 47-137 29 1.5e-18 58.2 In-house 49-157 (343) Show / Hide
Range on Protein: 47-137
Range on HMM: 49-157/343
Sequence Identity: 29% (32 aa)

NRYRDIHPYNHTRIRLERG------------DVRYINASLIEAP------LAKRKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYF
|||..| ||.|.|..|...               ||||. .. .       .. ||| ||.|| .||  |.... . . . |..|.. ||.  .||  |.
nrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYW

PRGQDNGNT
..|. .. |
qegsyddit

Phosphatase Spur_PTPN1.AA Subfamily.N_Fungi_PTP1.PD 172-246 30 1.5e-12 38.4 In-house 209-291 (343) Show / Hide
Range on Protein: 172-246
Range on HMM: 209-291/343
Sequence Identity: 30% (24 aa)

TQQTKEILHFHYTRWSDFSVPQSPAAFLQFLH--------HVRRSGSLVDNVGPPVIHCSAGVGRSGTLCLVDTCLVQIEKKG
. .|......  | | |.   |  .|| |          . .| .  ..  | ..|||||||| |||. .|  | ..|     
vsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeile

Phosphatase Spur_PTPN1.AA Family.DSP.PD 160-234 22 6.4e-07 20.3 In-house 148-204 (387) Show / Hide
Range on Protein: 160-234
Range on HMM: 148-204/387
Sequence Identity: 22% (17 aa)

YivrtllledlvtqqTKEILHFHYtRWSDFSVPQSPAAFLQFLHhVRRSGSlvDNVGPPVIHCSAGVGRSGTLCL
.              ...| . ..  ..|...|.    | ...  .  .|   |. |  ..|| ||.||||||. 
k--------------elgikylri-pidDhnapplenlfekaid-fieegn--dskgvVlVHCkaGkgRsgtlii

Phosphatase Spur_PTPN1.AA Subfamily.DSP23.PD 173-273 26 1.2e-06 19.9 In-house 28-116 (128) Show / Hide
Range on Protein: 173-273
Range on HMM: 28-116/128
Sequence Identity: 26% (26 aa)

QQTKEILHFHYTRWSDFSvPQSPAAFLQFLHHVRRSGSLVDNVGppvIHCSAGVGRSGTLclVDTCLVQIEkkGntsgLDVRKQLLDMRRYRHGLIQTWQ
... . | ..  .  ||  | ..    .... |  .    . ||   .||  |.||.|||  .   ||. |  |    |   . . ..|.|.| |.| .|
seaapsltlrridipdfc-PPaleqvarlvriveeaekkeeavg---vhcalGlGrtGtl--lacylvkee--g----laaddaiaevrkrrkGsietve

Q
 
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Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPN1.AA Protein None 440 None Fasta, JSON
Spur_PTPN1.NA RNA None 1320 None Fasta, JSON
Spur_PTPN1.AA.PD_3-286 Protein Phosphatase Domain None 284 None Fasta, JSON