Gene Spur_PTPN12
Spur_PTPN12
Species: S.purpuratus
Alias: Spur_PTPN12, hmm8194, Spur_hmm21727
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Spur_PTPN12.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | Spur_PTPN12.AA | PTPc | 29-297 | 34 | 1.1e-101 | 344.98 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 29-297 Range on HMM: 1-308/308 Sequence Identity: 34% (109 aa) SFELEFNHLKQISQRYRTEKVY----PTSAGESDVNM--RKNRYK-DILPFDHSRYLLSQIDNV----EGSDYVNANFLKGAANDHTYLAAQGPLPHTVN .|. ||..|.. . ... | ... .... |. .||||| ||...||.| |.... |||||.|||. .| . ..| ..|||||||.. GFWEEFERLQRMTPWDLMS-NYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIE EFWRMLWECNTEIIVMACNEFEL--------GRHKCERYWVDEGEEHCFGDILVTQIGQQRVTKDFMIRTLKATRDK----------EEKIFNQFHYTAW |||| |. ...|||| ||..| || ||..|| || . ..|.| || . . . .|. .||.. | .. |... ..|||.| DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNW PDHGVPTSVKPILDMIKLVREYQTAE-------------------EPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQ |||||| | ...||.|..||..| . ..|||||||||||||||.|.||.. . .. .....|. ||.||. || PDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQ TRNQYELVHRAVVDMFQ | || ..|.. . .. TEEQYIFCYRCILEYIK |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N12.PD | 30-297 | 57 | 3.4e-134 | 437.5 | In-house | 2-270 (270) | Show / Hide |
Range on Protein: 30-297 Range on HMM: 2-270/270 Sequence Identity: 57% (154 aa) FELEFNHLKQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE |. ||..||..|..|..||||.|.|||...|..|||||||||.|.||. ||.|...|||||.||||.||......|.|||||||.|...||||.||.|.| fakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknve IIVMACNEFELGRHKCERYWVDEGEEHC-FGDILVTQIGQQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPP |.||||.|.|||..||||||..||||.. ||.. ||.. ...|..||.|||||....||.....|||||||||||||.|.|..|..|.||||.|..|. | ivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaP IVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ .|||||||.||||||..|||||..|. |||.......|.....||||.|.|||..|||||..||..... lvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvk |
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| Phosphatase | Spur_PTPN12.AA | Y_phosphatase | 60-294 | 42 | 5.9e-100 | 343.18 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 60-294 Range on HMM: 1-243/243 Sequence Identity: 42% (105 aa) NMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKG-AANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGR-HK-CERYWVD--EGE |..|||||||...||.| |. |.. |.|||.|||. .| | ..| ..|||.|||...|||| |. ....||| ||..| || | |..|| | ||. NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ EHCFGDILVTQIGQQRVTKDFMIRTLKATRDK----EEKIFNQFHYTAWPDHGVPTS-VKPILDMIKLVREYQT-AEEP--PIVVHCSAGCGRTGTICVI . .||. || . . ..|...||.. | . |... ..|||.||||||| | .|..||.|. ||..|. . . ||||||||||||||| |.| PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI DYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD |.. .. |.. ....|. ||.||. ||| ||. ....... DIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.RB.PD | 45-296 | 39 | 7.9e-81 | 262.7 | In-house | 11-260 (261) | Show / Hide |
Range on Protein: 45-296 Range on HMM: 11-260/261 Sequence Identity: 39% (100 aa) RTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHK . .| ...| |. || |||.. |||.|||| |..... ...||.|||...| . . |.|.|||||.||..||||.|| ...|||| . .| |..| kvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkek CERYWVDEGEEHCFGDILVTQIGQQrVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAE--EPPIVVHCSAGCGRTGT ||.|| .. |.. .||| || . .. .....||..| ...||.. .|.|.|.||||||| . |..||... |||. ... . ||||||||| ||||| ceeYWPadeepvlyGdikvtllaek-eldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGt ICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF .| . .|.. .. .. .....|..| .||| .|| ..|....|.. fialdrllqaiee---ndyvdvfgvvaelReeRnllvqtekqyifiheclldll |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.R_Anemone_2.PD | 50-295 | 38 | 2e-80 | 261.5 | In-house | 17-260 (262) | Show / Hide |
Range on Protein: 50-295 Range on HMM: 17-260/262 Sequence Identity: 38% (93 aa) YPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYW ... ..|| .|||| .||..|..| .|......|||||.|||.. | ....|.|.|.|||.|...||||.|| |. .|||.| | |..|..||| ..| vtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryW VDEGEEhCFGDILVTQIgQQRVTKDFMIRTLKATRD--KEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ-TAEEPPIVVHCSAGCGRTGTICVI . .|.. |. .. ..|...|..| .| .||.. |||||.|||.|||.|. .||...|...| .... ||||||||| ||||. ...| . . Pskgsr-sygklvvelk-eevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiav DYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM .. |.. ..... .|.|| ..|||..|||... ..... dillerikaeal---vdvfqtvkqlreqrnlmvqtkdqyefiydvllea |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N6.PD | 31-293 | 40 | 3.4e-74 | 241.2 | In-house | 15-291 (295) | Show / Hide |
Range on Protein: 31-293 Range on HMM: 15-291/295 Sequence Identity: 40% (113 aa) ELEFNHLKQISqryrTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQI-DNVEGSDYVNANFL--------KGAAND-----HTYLAAQGPLPHTV . ||..|.. .|| | . || | .|||||.||||||.| |.. ..| ||||.|||.. .| . . ..|.|.||.|..|| weefeelqkqe----seklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtv NEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILVTQIGQqRVTKDFMIRTLKATR---DKEEKIFNQFHYTAWPDHGVPTSVKPILD ..|||| |. |. .|||. .| | |..|| ||| ||.... .|.| ||.| . |.|...|... .. |||.. |.|..||||||||.. . .|. sdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisE-kstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvln MIKLVREYQ--TAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV ... |.. | .. |||||||||.|||||. ||| | . .. ...| . .. .| |.|.|| .||| .||. | .|| fledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.R_Sponge_2.PD | 39-295 | 35 | 1.9e-73 | 238.6 | In-house | 4-260 (262) | Show / Hide |
Range on Protein: 39-295 Range on HMM: 4-260/262 Sequence Identity: 35% (92 aa) QISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQiDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEF .. . ..|. .|..... |. |||.|.|||.|.|| |.. |....|||.||.|. | . ..|.|.||||..||..||||.|| ....||| .| eeeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnle ELGRHKCERYWVDE-GEEHCFGDIlVTQIGQQRVTKDFMIRTLKATRDKE---EKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEP-PIVVHC | |..||..|| .. .|| .|.. . .. ... ..|..||.|| ...|. |. .|||..|||.|.||.. ..|..|| |.. |. ... .|.|.| engkekcakYWPekvdeeveygkf-kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvC SAGCGRTGTICVIDYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM |.| ||||| ...| | . | |.... ..... ..| .| .||. .||. .| |. .. sdgvgrtGtfialdsvlerl---kaeeeidvfevlktlrtkriglvqdaaqYvfihdalley |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Choan_1.PD | 50-296 | 36 | 1.2e-72 | 235.9 | In-house | 16-261 (262) | Show / Hide |
Range on Protein: 50-296 Range on HMM: 16-261/262 Sequence Identity: 36% (91 aa) YPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYW ...| ..| |. ||||..| .|..| ... .. . .||.||||..| ... |.|.|||.|.....||.|.|| . ..||| .| | |. || ||| ntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryW VDEGEEHCFGDILVTQIGQqRVTKDFMIRTLKA-TRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEE-PPIVVHCSAGCGRTGTICVID || .| .||. |... . . .| .. |..| ... |.. .|..||||||||||.. | .|. | |..... .. |.|.||||| ||||| .| Pdenselklgdvtvkslse-eekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyialD YVRNALQleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF . .|.. . .. .. ... ..||.| .||| ||| |..|| |.. rlvkave--ekaealdvkavvaelrkernlmvqtlvqyefvykavldal |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.RA.PD | 30-296 | 36 | 6e-72 | 233.6 | In-house | 2-265 (266) | Show / Hide |
Range on Protein: 30-296 Range on HMM: 2-265/266 Sequence Identity: 36% (101 aa) FELEFNHLKQISQryRTEKVyptSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE .| ||..| .. . ||. ... . |..|||. .|||.|.|| ||... .| |||.|| |..| . ....|||||. .||..||||.|| .. leeefkkltsvki--qkekl---rtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksa IIVMACNEFELGRHKCERYWVDEGEeHCFGDILVtQIGQQRVTKDFMIRTLK------ATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQT ||| . | ...|| .|| ||| ..|.| | .. .. |..|. .| . |||.|.... .|||.|.||. |||.. | .|...| |.. | tivmltelkerkeekcaqywpdeGl-vtyGeirv-evkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqq AEEP-PIVVHCSAGCGRTGTICVIDYVRNALqleKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF . ||||||||| ||||| .|.| | . . | .. ..... .|.|| .||| .|||...... . . qsanhpivvhcsaGvGrtGtfivldavlerv---kaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.R_Anemone_1.PD | 41-295 | 37 | 6.1e-69 | 224.0 | In-house | 6-256 (258) | Show / Hide |
Range on Protein: 41-295 Range on HMM: 6-256/258 Sequence Identity: 37% (94 aa) SQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFEL ||....| ..... . | .||||.||...|||| .|.. .| | |||.|| .|.. . ....|.|.||..||..||||.|... .||| | | fqrlkeikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnlieg GRHKCERYWVDegEEHCFGDILVTqIGQQRVTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCG .||..|| | ... .|.. |. . .. | |..||||. ...| ||.. |.|.| |||.|||.. .|.. . |.. ..|.. |.||||||| ||||. ekkkchqYwPd--stekygelrvs-lrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvg RTGTICVIDYVrnaLQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM .||| . |. | .. ..... .|..| .|||..|| .|.||... RtGaflvidam---leqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.R_Ecdysozoa.PD | 30-295 | 34 | 4.7e-68 | 220.7 | In-house | 2-267 (269) | Show / Hide |
Range on Protein: 30-295
Range on HMM: 2-267/269
Sequence Identity: 34% (95 aa)
FELEFNHLKQISqryRTEKvyPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTE
.| |...|.. ..| |...| . | ||||.|| .||. | |..| | |||.||.|.|| . ....|||.|.|...||||..| . ..|
leeeyekLearl---eisk--stkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevt
IIVMACNEFELGRHkCERYWVDEgEEHCFGDILVTQIgQQRVTKDFMIRTLKATRDK-----EEKIFNQFHYTAWP-DHGVPTSVKPILDMIKLVREYQT
|| |. | |. |..|| .| .| .|||||. . ... ..|..||.|. .. | ... |..||.|. | || . . .|..|. |||.. .
livmlsnlteknrk-cakyWpie-devqygdilvklv-seekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyk
AE-----EPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM
. ||||||||| ||.|.. .| . . |..| .. ...... ..|.|| .|| .||. ..||..|.
lnklsgsrsPivvhCsaGvgrsgifvaldlllqqlkae---dkvdifetvkkLrsqrnllvqsleqyvflyralady
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N9.PD | 56-294 | 37 | 2.4e-67 | 218.7 | In-house | 22-272 (275) | Show / Hide |
Range on Protein: 56-294 Range on HMM: 22-272/275 Sequence Identity: 37% (94 aa) ESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGE .. .|..||||.|.| .|..| |...|. | |||.||||..| . ....|.||||..||..||||.|| .. .|||. | || || .||.|.. . klranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleees EHCFGDILVTQIGQQrVTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQT-------------AEEPPIVVHCSAGCGR |||. |...... |..|...|.|... ...|.. | ...|||.||| | . .||... |||.|. ...|||||||||| |||| saefgdlsvsnveve-veedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGr TGTICVIDYVRNALQleKIdQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD | . .|. . |. .. .. . . . .|.|| .|| .|||. . ||.. tGtfitldiclarle--ev-gtvdvvetvkllrtqrafsiqtpeqyefcylavle |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N3.PD | 38-296 | 36 | 5.5e-67 | 217.1 | In-house | 4-260 (261) | Show / Hide |
Range on Protein: 38-296 Range on HMM: 4-260/261 Sequence Identity: 36% (98 aa) KQISQRYRTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNvegsDYVNANFLKGAAND----HTYLAAQGPLPHTVNEFWRMLWECNTEIIVM .| . || . .|| |. ||||.||||.|. | |.. .. ||.|||... . |.|.||||..|...||.|.|| ....||| aqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivm ACNEFELGRHKCERYWVDEGEEHCFGDILVTqIGQQRVTKDFMIRTL--KATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVV . | || || .|| ....| ||.. |. . ... || ...| | | .. |||. |. |.||||||||.. . .|.... ||......|.|.|| lttlverGrvkChqyWPetedelefgefsvr-cekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvv HCSAGCGRTGTICVIDyvrNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF ||||| |||| . ... ||.| . ... ||. || || ..||| .||..| |.. .. hCsaGigrtGvlille---talalieaaepvypldivrtmrdqramlvqtvsqykfvCeailkay |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N13.PD | 50-295 | 36 | 4.1e-66 | 214.6 | In-house | 16-257 (259) | Show / Hide |
Range on Protein: 50-295 Range on HMM: 16-257/259 Sequence Identity: 36% (90 aa) YPTSAGESDVNMRKNRYKDILPFDHSRYLLSQidnvEGSdYVNANFLKGA--ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCER .. |... |..||||...||.|..| |.. ||. |.||...| . ..|.|.|||||.||..||.|.|| ..|.|.| .| ||. ||.||| dtcevgkkkenkdknryrnvlPydetrvklgd----egg-yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchr YWVDEGEEHC-FGD-ILVTQIGQQRvTKDFMIRTLKATR--DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaEEPPIVVHCSAGCGRTGTI .. ... . . |.....|. ..| .|.|. . .| . ......|||||||.| .... ... ||. || .. ||||||||| ||.|.. .| ywPerknkklkvsnrlevellkvqk-ldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhcsaGiGrsGvl CVIDYVrnaLQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM | | |.| . |..| . .|. ..|.||...|||..|| .|..|.... itidvv---lglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Choan_2.PD | 57-295 | 37 | 3.9e-65 | 211.1 | In-house | 18-264 (266) | Show / Hide |
Range on Protein: 57-295 Range on HMM: 18-264/266 Sequence Identity: 37% (92 aa) SDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAAN-DHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEE | | |||.|||| ..| |..... . . |.|||...|. . ...|.||.|||| |...||||.|| ... |||. . | ||.|||||| | .|.. yarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke HC---FGDILVTQIGQQRvTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVK------PILDMIKLVREYQT--AEEPPIVVHCSAGCGRTGTIC |.| |... ... .. .... |. ....|.. |.|..|||||||.. .|.|.. ||... ... |..|||||| |||||. .||. kvkladgkikvlalseek-eegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtli VIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM . ..|. . .. . || ..||.| |.||. .||||...|||. aiDiavrlLeet---kkvdvlaiieelRkdRmalvqhpeqyellykavvey |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.RG.PD | 39-295 | 31 | 4.4e-64 | 207.9 | In-house | 8-262 (264) | Show / Hide |
Range on Protein: 39-295 Range on HMM: 8-262/264 Sequence Identity: 31% (83 aa) QISQRyrTEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEF .|.. ..| .... .. | .|||. .|.....|| ||.. ...|.||.||....| . |...||||..|...||||.|| |..|||| . eiqkl--kpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdld ELGRHKCERYWVDEGEEHCFGDILVTQIGQQR----VTKDFMIRTLKATRDKEeKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCS | ||.....|| .. | .... ||.. ... ...||.... | ..|| . .|.||| |||.|.|.| . | ..| ...| |||||.| ekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkeke-rvvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhds AGCGRTGTICVIDYVRNALQLEKidqNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM || ||.|| ...| . . |. |. . .|... .|..| .|.|..|| .. |.... aGvgragtyialdtllqqlekee---avnvyqvlklirakRpglvtteEqyvfiydallel |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.RK.PD | 32-295 | 30 | 4.1e-62 | 201.2 | In-house | 4-265 (267) | Show / Hide |
Range on Protein: 32-295 Range on HMM: 4-265/267 Sequence Identity: 30% (83 aa) LEFNHLKQISQRYRTEKvypTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVeGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEII ||. |.... . ..|. ... | | .|||..|||..|.|. | ..|. |||.||... . . . ....||||..||..|||....|. ||| eefetlnsvtpelqsed---cdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasi VMACNE-FELGRHKCERYWVDEGEeHCFGDILVTQIGQqRVTKDFMIRTLKATR----DKEEKIFNQFHYTAWPDH-GVPTSVKPILDMIKLVREYQTA- . | || || .|| ...| ...||| |. . . .|...|... .. .| .. .||....||.. .||.| . .|..|. | . | || vmlteldvevgrvkClkyWPedte-vrygdikvelvea-eldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeee EEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM .|||||.||.||.|| ..|| | . .. |.. .. .. ..|... .|.| .||..|. ..... eeGrivvhClaGaGrsGtfiaidivlemieregv---vdvfnavktlrnrkvnmveteeqykfvydvilea |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N5_RR.PD | 61-293 | 36 | 1.3e-61 | 199.7 | In-house | 24-261 (265) | Show / Hide |
Range on Protein: 61-293 Range on HMM: 24-261/265 Sequence Identity: 36% (87 aa) MRKNRYKDILPFDHSRYLL-SQIDNVEGSDYVNANFLKGAAN-DHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEE--- .|||||.||| ..|| || |. . | |.|.|||..|| . ...|.|.|||||.|...||||... ....||| . | |.||..|.|. . . qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeis HCFGDILVTQIGQQRvTKDFMIRTLKATRDKE-EKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAE---EPPIVVHCSAGCGRTGTICVIDyvrN .||. .. . . ..|. .|.| . .. |. . ||.|||| .| .....||... |.| ...| |.||||||| |||| |. .|. erygdveikveeive-rndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiais---i ALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVV . . .. . |....| .| .|||..||||.|||.. avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.RN.PD | 43-294 | 35 | 6.5e-57 | 184.2 | In-house | 11-261 (264) | Show / Hide |
Range on Protein: 43-294 Range on HMM: 11-261/264 Sequence Identity: 35% (88 aa) RYRTEKVYpTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGA-ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELG .|..|. ....... |..|||.|..||.|||| |.. . | |||.|| .. .|.|.||||..|. .||.|.|| . .||. .. | | ayeaepst-kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeeg RHKCERYWVDEGEEhCFGDILVTQIGQQRVTKDFMIRT--LKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGR ..|.||| |||.| .. | . . ..|...|. || . .| . |||. .||..|||.| |..|.. . ||||||||.|.||||. ..|| vkqckrywpdeGse-vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGr TGTICVIDYVRNalQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD | . .| | .. . . .| ||. .|.|..|.|.. ||.. tGvyilidlvle--rllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N1.PD | 46-294 | 32 | 3.8e-54 | 175.3 | In-house | 14-265 (268) | Show / Hide |
Range on Protein: 46-294 Range on HMM: 14-265/268 Sequence Identity: 32% (84 aa) TEKVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNvegsDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKC .|| ..|.. . . | .|||.|. |.|||| | . |. ||.||.... .. |. .|||||||.. ||.| || |. ..| . |.. || kekeletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikC ERYWVDEGEE--HCFGD--ILVTQIgQQRVTKDFMIRTLKAT--RDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQT--AEEPPIVVHCSAGC ||. | || . . . |. | .. ... |. |.|. . ...| . .|||| ||| |||.| . .|... ||| . .|.|.||||| ||. aqywpqeeeeaellleetklkvkli-seerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagi GRTGTICVIDYVRnaLQLEKIDQ--NFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD ||....| . ...|| .. . . ....||.|. ..|| .| . |... grsgtlslvdtcl--veiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_1.PD | 33-296 | 32 | 3.1e-52 | 168.9 | In-house | 5-264 (265) | Show / Hide |
Range on Protein: 33-296 Range on HMM: 5-264/265 Sequence Identity: 32% (88 aa) EFNHLKQISQRYrTEKVYPTsAGESDvnmrKNRYKDILPFDHSRYLLSQidNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIV ||..||. .. . |.. . | |.| ||||||. |..| |.. . |||. ||.. ..| . .. ||.|| .|...|| |. . | || efralkkfndee-kvkafke-aqead----knrykdvgcldknrvklae--eplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaiv MACNEFELGRHKCERYWV-DEGEEHCFGD----ILV---TQIGQQRVTKDFM-IRTLKATR-DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREyq | |. | |..||. |. |||. | . | | ... .. ..... . .|. . .........| |||.|||. .|.... ||. mlckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrg-- taEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQnfSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF .. ||||||||| |||||| .|.|. . | .|. . ... ..|.||. .|| || ||| ... | --skgPivvhCsaGiGrtGtivaieyildkllegkqie--dmeklvkkireqrnysiqtdaqylfvhrvllnyf |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.RC.PD | 48-297 | 28 | 8.3e-52 | 167.6 | In-house | 14-288 (288) | Show / Hide |
Range on Protein: 48-297 Range on HMM: 14-288/288 Sequence Identity: 28% (80 aa) KVYPTSAGESDVNMRKNRYKDILPFDHSRYLL-------------------SQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNT .. .. . | |||| |.||.|. | | ..|| |||.|.|| |... . . |.|||||| ||..||||..| ... skrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkv EIIVMACNEFELGRHKCERYWvDEGEeHCFGDILVtQIGQQRVTKDFMIRTLKATR--DKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVR------- ||| . | |.|| .|| .||. ...||. | .. .. . |...| |. . .|. . |. ||.|.....| | .|..|..|. kvivmltelkeGdrekcaeyw-eeGk-rayGdvev-dlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkr ---EYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMFQ .. |..|||..| .|||. . .. . ..|. | . ...... .||.| .|.. .|| |.. ..|...| sseafknfkstpllvhcrdGsqrtGifiallallesleae---ekvdvfqvvkklrkarplmvsveeqyillydvlvetyq |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N14.PD | 51-295 | 33 | 4.3e-51 | 165.1 | In-house | 17-273 (275) | Show / Hide |
Range on Protein: 51-295 Range on HMM: 17-273/275 Sequence Identity: 33% (85 aa) PTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVeGSDYVNANFLKG--AANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERY .|... ..| .|||.||.||....| || . ..|.|| .| ......|..|||||..||..||.|.|| ....||| .| | |..|. .|. llstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfky WVDEGEEHC---FGDILVTQIG-QQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILD---MIKLVREYQTAE-------EPPIVVHCS ...... || ||. .. . . .|| |||. . || ||||||| ||. |. ... ||. . |.||..|||||| |||| lPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCs AGCGRTGTICVIDYVRNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM . . | . ..|. ... . .. .|||| .||| ||..|..... . aGvGrtGvlilsdlliatleh---neeidikkvlarLrkqrmllvqtlaqykfvykvliky |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_4.PD | 45-295 | 30 | 3.9e-48 | 155.5 | In-house | 10-262 (264) | Show / Hide |
Range on Protein: 45-295 Range on HMM: 10-262/264 Sequence Identity: 30% (77 aa) RTEKVYPTS-AGESDVNMRKNRYKDILPFDHSRYLLSQIDNveGSDYVNANFLKGAaNDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRH . .| |. | |. |. ||||.||| |..| .| . | ||. |.... .. .|...||||..|...|| |.......|| |. .| | .|| vkgkappnvtasaseknsdknryadilcidetrvvlknrdp--dndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegve KCERYWVDEGEE-HCFGDILVTQIGQQRV-TKDFMIRTLKATRDK-------EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREyqTAEEPPIVVHCS .||. .. |. . ||. .|.. .. | ....|| | . |. ... .... |.|.| .|.....| |.. .| ||||||||| | kcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcs AGCGRTGTICVIDYVRNALQlEkiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM || |. ||| . .. | . . ||. ..|. | ||.. |.. .... aGvGrtatlvGidyatirir-e--nseievldivrelramrlkavqshlqflfllvvliel |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N23.PD | 84-294 | 31 | 6.1e-45 | 145.2 | In-house | 127-347 (350) | Show / Hide |
Range on Protein: 84-294 Range on HMM: 127-347/350 Sequence Identity: 31% (69 aa) NVEGSDYVNANFLKGAAN-DHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYW-VDEGEEHCFGDILVTqIGQQRVTKDFMIRTLK . .||.|| .|| . ...|.|||.. |...|| |.|| ...||| .| | .. ||..|| |||| . |||. |. . ..| .... |.|. . pgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvs-lkslrssegwiervlh ATRDKEEKI--FNQFHYTAWPDHGVPTSVKPILDMIKLVREYQ-------TAEEP--PIVVHCSAGCGRTGTICVIDYVRNALQleKIDQNFSLYDIIVD .. ... ..|.|.|...||| | . .|.... |... |..|. ||..||||| |||||.||. . ..|.. . . ... .|.|| lqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelt--agngiiniprvvrr MRKQRHAIVQTRNQYELVHRAVVD . ||...... . .||. lrqqRkymvqkkvilkklyeavle |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_6.PD | 60-295 | 33 | 2.6e-44 | 143.0 | In-house | 24-251 (253) | Show / Hide |
Range on Protein: 60-295 Range on HMM: 24-251/253 Sequence Identity: 33% (78 aa) NMRKNRYKDILPFDHSRYLLSQIDNVegsdYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDE-GEEHCF . .|||..| .| .| |.. .. |. ||..| ... . .. .|.|| |..|||.|. .| ||| |. | |..|. .| |. |... . fkdrnrytniqCcdagrlkladdedf----yihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarki GDiLVTQIGQQRVTKDF--MIRTLKATRDK-EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaeepPIVVHCSAGCGRTGTICVIDYVRNALQL .. | |.| .|. .| . ... ... || | . .|. .||||||| |.. | ....|.. .||||||||| |||||. .| . .||.| . tk-lctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk----PivvhCsaGvGrtGtlaliliilealrl EKIdqnFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM .. |..| .|..| ||| || ..| |.. pdf---qgvkdllvklreerfravqtevqylyalrcvley |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.R_Nematode_2.PD | 59-294 | 28 | 6.9e-44 | 141.5 | In-house | 28-258 (261) | Show / Hide |
Range on Protein: 59-294 Range on HMM: 28-258/261 Sequence Identity: 28% (67 aa) VNMRKNRYKDIlPFDHSRYlLSQIDNVEGSDyVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWV-DEGEEHC .. |.||.|. | . . . | . . .. . ||.. | |.. ..|.|||| |...|| |. . | ||| |. | ..|||.|. ..... lpkdkhRypdv-PCkpeta-vevivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld FGDILVTQIGQQRVTKD-FMIRTLKATRDKE---EKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREyqtaEEPPIVVHCSAGCGRTGTICVIDYVRNAL .| . ... ..... || . |||| . . . . . |. |||.||| | . . ....||...| ||||||||| |||... ..|. .... lgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkk----sekPivvhCsaGiGRtmafigteylarev QLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD |.. .| . . ..|..| .||..|. .... . ea---dptieltealkelrehRwkgiqtesqlywltlgaly |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N20.PD | 54-295 | 32 | 3.3e-43 | 139.6 | In-house | 20-255 (257) | Show / Hide |
Range on Protein: 54-295 Range on HMM: 20-255/257 Sequence Identity: 32% (80 aa) AGESDVNMRKNRYKDILPFDHSRYLLSQidnveGSDYVNANFLK--GAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVD .|. | ||||.||||.| .| | . ||.||.... . ... |.|.|||| |...||.|. | |...| | | | | || .|| sgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpi EGEEHCFGDILVTQIGQQRVTKDFMIRTLKATRDK--EEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAeePPIVVHCSAGCGRTGTICVIDYV .. . . . .. . |.|| .. . .|...| ||||| |.| .. |. |. . . |.||||||| |||| . ..| | slkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshlt--gpmvvhcsagigrtgvflcvdvv RNALQLekiDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM |. . .| . ||. .||.|| .|||..|| ... |... fcaivk---ncsfnimdivaqmreqrsgmvqtkeqyhfcydivlev |
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| Phosphatase | Spur_PTPN12.AA | PTPc_motif | 190-294 | 40 | 7.7e-38 | 132.95 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 190-294 Range on HMM: 1-92/92 Sequence Identity: 40% (44 aa) IFNQFHYTAWPDH-----GVPTSVKPILDMIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMRKQRHAIVQTRNQ . ...|||.|||| |||. ..||..|..||. |||||||||||||||.|.||.. . .. .... |||||. ||| | TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQTEEQ YELVHRAVVD | ..|.. . YIFCYRCILE |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.R_Nematode_3.PD | 48-295 | 24 | 1.3e-36 | 117.7 | In-house | 11-265 (267) | Show / Hide |
Range on Protein: 48-295 Range on HMM: 11-265/267 Sequence Identity: 24% (62 aa) KVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKgAANDHTYLAAQGPL--------PHTVNEFWRMLWECNTEIIVMACNEFE |. ...| . . .. ..|..... . ..| .| . . .|...||... .|. .|.|. |.. || |. ..|..|| |. | klakknatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfve ---LGRHKCERYWVDE-GEEHCFGDILVTQIGQQRVTK-DFMIRTLKATRD-KEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTaeepPIVVHC . .|| .|. .. ..| |... |. . .. .. |. |||. | . |.|. .. .|..|.....| . |..|..|| |....| |.|||||. edgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfvekskt----pvvVHC SAGCGRTGTICVIDYVRNALQLEKIdqNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM | .|..|. .|... . . .| ...| ..| ..||||. .|| ..| .... sdGisRsatlaaielgyqliikskg--kldllslikelrkqRagaiqtelelafvilgilkl |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_5.PD | 59-294 | 24 | 6.3e-36 | 115.3 | In-house | 24-255 (258) | Show / Hide |
Range on Protein: 59-294 Range on HMM: 24-255/258 Sequence Identity: 24% (59 aa) VNMRKNRYKDILPFDHSRYllsqIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCF |. |||.||. |..| . . | ..|.||. .| .... .| |||.|...|||| . . . .|..... || .... . .|. .|. knlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdylnl GDILVTQ--IGQQRVT-KDFMIRTLKATrDKEEKIFNQFHYTAWPDHGVPTSVKPILD-MIKLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRNALQ .... . .. | ... .| . |. . . |.| |... ||..||... .|. | . ......|.||....|.||.||. ..... . |. . gkmfinnrkvevkedekkeytvevlpeg-csesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqln LEkidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVD ... . .|. .|.|| .|.. || |..||.| ng---kepnideilkkirsqRpgavesliqyasvyaavld |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Fungi_PTP1.PD | 61-152 | 35 | 1.9e-24 | 77.7 | In-house | 46-151 (343) | Show / Hide |
Range on Protein: 61-152 Range on HMM: 46-151/343 Sequence Identity: 35% (37 aa) MRKNRYKDILPFDHSRYLLS--------QIDNVEGSDYVNANFLKGA------ANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCE . |||||.|||..||| | . ....||.|||.|| . |. |.|.|.||| ||..|.... . . ..|.. ...||...||. faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy RYWVDE ||| . rYWqeg |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_egg.PD | 31-296 | 24 | 1.6e-23 | 74.9 | In-house | 3-256 (257) | Show / Hide |
Range on Protein: 31-296 Range on HMM: 3-256/257 Sequence Identity: 24% (65 aa) ELEFNHLKQISqryrTEKVYPTSAgeSDVNMRKNRYKDILPFDHSRYLLSQIDNVEGSDYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEI | .|. |.. |. . |.| || .. | | | . . || | |.. ||..|| ... || ||||..||||... . . || errfeilersv----deislttaa--sdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqy IVMACNEFELgrHKCERYWVD-EGEEHCF--GDILVTQIGQQ-RVTKDFMIRTLKATRDKEEKIFNQFHYTawpDHGVPTSVKPILDMIKLVREYQTaee | | ..|| || | | . | . .. .. . . | . || ..|.| . | . | | .....|. . |. ivmltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg---dvnylsdvysplrvlrklrnlsk--- pPIVVHCSAGCGRTGTICVIDYVRNALQLEKIdQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDMF ||.. |. ...|. |. | | . . .| .|..|. |.. .| .|.| |. .. -pvvvqdilGvskaatlvaieiallsllrGpi-tkslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Fungi_PTP1.PD | 188-296 | 26 | 8.6e-19 | 59.1 | In-house | 212-342 (343) | Show / Hide |
Range on Protein: 188-296 Range on HMM: 212-342/343 Sequence Identity: 26% (35 aa) EKIFNQFHYTAWPDHG---VPTSVKPILD----MI---KLVREYQTAEEPPIVVHCSAGCGRTGTICVIDYVRN-ALQLEKIDQNF-------SLYD--- .. |... |.| . | |. ..|. .| ...|. .||.||||||.|||||.. .|.. . . ||.. ... . | pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlis -IIVDMRKQRHAIVQTRNQYELVHRAVVDMF |. .|||| .||. .|. .. |. .| iivnelrkqrismvqnldqfifiYeallfyf |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.PTPDC1.PD | 194-290 | 35 | 1.8e-13 | 41.9 | In-house | 137-222 (229) | Show / Hide |
Range on Protein: 194-290 Range on HMM: 137-222/229 Sequence Identity: 35% (34 aa) FHYTAWPDHGVPtSVKPILDMIKLVReyQTAEEPPIVVHCSAGCGRTGTICVIdYVRNAlqlekidQNFSLYDIIVDMRKQRHAIVQTRNQYELVHR |. ...|.||. |.. |||..|.| .. || | ||| || |||| . |. | .... . | .|..| .|||.| |||. fynfglkDygva-sleriLdivkvvd--faleegkiavHCHAGlGRtGvliac-ylvya-------krltaeeaiklvrskrpksiqtreqvelvee |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_eak.PD | 51-206 | 20 | 6.3e-12 | 36.8 | In-house | 17-171 (281) | Show / Hide |
Range on Protein: 51-206 Range on HMM: 17-171/281 Sequence Identity: 20% (32 aa) PTSAGESDVNMRKNRYKDILPFDHSRYLL-SQIDNVEGsdYVNANFLKGAANDHTYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYW . .. ....|| .|.|.|. | | | .| |.|| .. . . |. . . . | ||.|. | .. ||. .. |.. | ..|. | sirvtarleavnrnrvvkivpqdrylvrltssqlnrdG--yinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyf VDEGEEHCFGDILVTQIGQQRVTKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPT ..|. .| . |.. . . | |. .. | . ... | . .| pdktevlkyGildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpk |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.DSP23.PD | 200-289 | 27 | 2.4e-11 | 35.2 | In-house | 42-121 (128) | Show / Hide |
Range on Protein: 200-289 Range on HMM: 42-121/128 Sequence Identity: 27% (25 aa) PDHgVPTSVKPILDMIKLVREYQTAEEpPIVVHCSAGCGRTGTICVIDYVRNalqlekidQNFSLYDIIVDMRKQRHAIVQTRNQYELVH ||. | ... . ....| | . || .. ||| |.|||||. .|.. .... | |...||.|. ..|..| ..|. pdf-cPPaleqvarlvriveeaekkee-avgvhcalGlGrtGtllacylvke--------eglaaddaiaevrkrrkGsietveqekavk |
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| Phosphatase | Spur_PTPN12.AA | Family.DSP.PD | 172-285 | 17 | 1.7e-10 | 32.2 | In-house | 140-236 (387) | Show / Hide |
Range on Protein: 172-285 Range on HMM: 140-236/387 Sequence Identity: 17% (21 aa) TkdfmirtlkatRDKEEkiFNQ-----FHYTAWPDHGVPTSVKPILDMIKLVREYQtAEEPPIVVHCSAGCGRTGTICVIDYVRNalqlekidQNFSLYD | ||.. |.. .. ...||..|. . . |. . | . .. ..||| || ||.||.... . . ....| . t-----------ddkpq--ftkelgikylripidDhnapplenlfekaidfieegn-dskgvVlVHCkaGkgRsgtliiaYlmks--------egltlee IIVDMRKQRHAIVQTRNQY . .|..| ... .... aldwvrskRpgvitpnqgf |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.PTEN.PD | 175-267 | 23 | 1.2e-08 | 26.0 | In-house | 42-134 (305) | Show / Hide |
Range on Protein: 175-267 Range on HMM: 42-134/305 Sequence Identity: 23% (22 aa) FMIRTLKATRDKEEK-IFNQFHYTAWPDHGvPTSVKPILDMIKLVREYQTAEEP-PIVVHCSAGCGRTGTICViDYVRNALQLEKIDQNFSLYDI .|.|.| ..||. . .. . || | ... . .... | .. ... ..||| || ||||.. . |. . .. .. |. ..|| gklrilnargekedsdfdgrvavypfdDhn-pptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmic-ayLlksgikksadealaiyde |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.N_Nematode_eak.PD | 229-295 | 23 | 5.5e-07 | 20.6 | In-house | 214-279 (281) | Show / Hide |
Range on Protein: 229-295 Range on HMM: 214-279/281 Sequence Identity: 23% (15 aa) IVVHCSAGCGRTGTICVIDYVRNALQlEKIDQNFSLYDIIVDMRKQRHAIVQTRNQYELVHRAVVDM .. .. | |.|. ||| . . .. .|. . .|. |.|. ....| | . |. ... .|.| piiqsarGsaraGvfvvidllirlid-nkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.PTPMT1.PD | 172-286 | 16 | 2.6e-06 | 18.7 | In-house | 33-138 (146) | Show / Hide |
Range on Protein: 172-286 Range on HMM: 33-138/146 Sequence Identity: 16% (19 aa) TKDFMIRTLKATRDKEEKIFNQFHYTAWPDHGVPTSVKPILDMIKLVREYQTAEEpPIVVHCSAGCGRTGTIcVIDYVRNAlqlekidQNFSLYDIIVDM .... ...| . .. .| .. . | |.. |.. . . .... .... .. . ||| || .| .|. |. |. . ...| . . . neeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvaskgs-svYvHCkAGrtRsatl-vacylmkk-------kklspeeavkfl RKQRHAIVQTRNQYE .|.|. | .|.. kkkRpqirlkskqwr |
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| Phosphatase | Spur_PTPN12.AA | Subfamily.TPIP.PD | 200-244 | 38 | 3e-06 | 18.4 | In-house | 11-55 (245) | Show / Hide |
Range on Protein: 200-244 Range on HMM: 11-55/245 Sequence Identity: 38% (17 aa) PDHGVPTsVKPILDMIKLVREYQTAEEPPI-VVHCSAGCGRTGTIC || ||| .. .. . | |.|. ... . ..|| | |||||| ddhnvPt-leelvvftkevkewlakdlenvvaihckGGkgrtGtiv |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Spur_PTPN12.AA | Protein | None | 967 | None | Fasta, JSON |
| Spur_PTPN12.NA | RNA | None | 2901 | None | Fasta, JSON |
| Spur_PTPN12.AA.PD_29-297 | Protein Phosphatase Domain | None | 269 | None | Fasta, JSON |