Spur_PTPN13
Species: S.purpuratus
Alias: Spur_PTPN13, hmm67275, Spur_hmm96919
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N13
Protein domain

Protein domains of Spur_PTPN13.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Spur_PTPN13.AA Subfamily.N13.PD 132-392 62 2.9e-141 461.0 In-house 1-259 (259) Show / Hide
Range on Protein: 132-392
Range on HMM: 1-259/259
Sequence Identity: 62% (162 aa)

DPAEEFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSGPsdYINASHIKAQVGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVT
.||||||.||..|..|.||..||..||||||.|||||||.|||.|.|.|.  |||||.||..||.|.|||||||||||.|..|||.|||||.|.||||||
qPaeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt

MDVESGKVKCHRYWPESANSPLMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDRLPIVVHC
...|.|||||||||||..|..|.|.||.||.|...|.||.|..|.. . |.|..|...|...||..||||.|||.. .|..|....|....|..||||||
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhc

SAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEALK
||||||.|.|||||..||||.||.||.| .||. ||.||||..||||||||.|||.||.||
saGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk

Phosphatase Spur_PTPN13.AA PTPc 132-392 32 1.6e-108 367.75 SMART 1-308 (308) Show / Hide
Range on Protein: 132-392
Range on HMM: 1-308/308
Sequence Identity: 32% (104 aa)

DPAEEFKTLRQVKAID---------NCEEAKKAQNK--DKNRFR-NVLPYDKTRVILEDS-------GPSDYINASHIKAQVGKDTYEYIACQGPLPNTT
  .|||..|....  |         .|..|..  |.  ||||.. ....||.|||.| .        ..||||||..|.    . . .||..|||||.| 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI

QDFWLMVWEQRADVIAMVTMDVES--------GKVKCHRYWPESANSPLMVYNRIEVRLENYQNLD-NFSIRRILMIDNET--------SEVHHVTQMNF
 ||| |||.|.  .|.| ....|         |..|||.|||.      |.| .|.| ........ .. .| .   . ..        ||.. ||. ..
EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE----PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHY

ATWPDHSVPSTSLPLLRFACHMRRIHDDR--------------------LPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQ
 .||||.||... ..|.|   .|  .  .                     |||||||||.|||||...||... .|..   . ...||| .|.|| ||.|
TNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQ

TKDQYIFCYKAALEALK
|..||||||...|| .|
TEEQYIFCYRCILEYIK

Phosphatase Spur_PTPN13.AA Y_phosphatase 157-389 37 6.2e-104 356.39 Pfam 1-243 (243) Show / Hide
Range on Protein: 157-389
Range on HMM: 1-243/243
Sequence Identity: 37% (92 aa)

NKDKNRFRNVLPYDKTRVILE---DSGPSDYINASHIKAQVGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGK-VK-CHRYWPESANS
||.|||......||.|||.|    . ..||||||..|.  ...   .||..|||.|.|  ||| |||.|.  .|.|.. ..| |. .| ||.|||... .
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG

PLMVYNRIEVRLENYQNLDNFSIRRILMIDNET--SEVHHVTQMNFATWPDHSVPST-SLPLLRFACHMRRIHD---DR-LPIVVHCSAGIGRTGTLITI
  |.| ...| ..... .... .|   . . ..  .|.. ||.  . .||||.||.. . ..|.|   .|  .    .  .|||||||||.|||||...|
QPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI

DAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
|... ........ ...||| .|.|| ||.|| .||||||.. ||
DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Spur_PTPN13.AA Subfamily.N3.PD 137-390 41 1.3e-83 271.8 In-house 6-259 (261) Show / Hide
Range on Protein: 137-390
Range on HMM: 6-259/261
Sequence Identity: 41% (106 aa)

FKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSGPsDYINASHIKAQVGKDT--YEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDV
|..| . |    ...|.|..| .|||.|..||||.|||.|..|   |||||.... ..   .    |||.||||..|..||| |||||.. .||.|  ||
feelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlv

ESGKVKCHRYWPESANSplMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIH-DDRLPIVVHCSA
.|.||||.||||. ..  . . ...||.|. ..  .. .| ... |.||.| ....|. .  ||||.||. |  .|.| ...|..... |.|||||||||
erGrvkChqyWPetede--lefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsa

GIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEA
||| ||...  | ||.. |.. .|.||. .| ||. ..||..|| |  .| |.|   
GigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka

Phosphatase Spur_PTPN13.AA Subfamily.RB.PD 134-391 41 1.2e-82 268.7 In-house 3-260 (261) Show / Hide
Range on Protein: 134-391
Range on HMM: 3-260/261
Sequence Identity: 41% (108 aa)

AEEFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVIL---EDSGPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMV
.||...|..|.  .....|..|.|..||||.|.||||..|| |   .|.  .|||||..|.    .   ||||.|||||.|..||| ||||....| |.|
seeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgy--nspreyiatqGPlpetvddfWrmvwekkssiivml

TMDVESGKVKCHRYWPESANSplMVYNRIEVRLENYQNLDNFSIRRILMiDNeTSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDR---LPI
  || ||.||..|||.. ..  ..|  |.| | . ..||.. || . .  .  .| ..|.|..| .||||.||... .||.|  ..|. ....    |||
tqlvEkgkekceeYWPadeep--vlyGdikvtllaekeldewvirefki-ek-gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPi

VVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
||||||.||||| |..| .|  |....   |. .|  ||..|. ..||..|||| ... |. | 
vvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase Spur_PTPN13.AA Subfamily.N_Choan_1.PD 135-391 38 1.8e-78 255.1 In-house 4-261 (262) Show / Hide
Range on Protein: 135-391
Range on HMM: 4-261/262
Sequence Identity: 38% (100 aa)

EEFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVIL---EDSGPSDYINASHIKAQVGKDtyEYIACQGPLPNTTQDFWLMVWEQRADVIAMVT
||...|...   . .. .|. .|. |||..|.  ||.||| .   |..  .|||||.....  |.   ||||.|||.|.. ..|| |||||....|.|||
eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgek--eyiatqgPvPaslvsfWqmvweqkvsaivmvt

MDVESGKVKCHRYWPESANspLMVYNRIEVRLENYQNLDNfSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDRL--PIVV
 ..|.||.|||||||. ..   . .  . |. .. ..  . .|.| .....|..|  .|.|... .|||| ||.|.  || |   ...... .   |.|.
reieagklkChryWPdens--elklgdvtvkslseeekkt-yierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvi

HCSAGIGRTGTLITIDAILGLIDRDEEF-KVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
|||||.||||| |..| ..  .....|  .| ..|. |||.|. |.||  || | ||| |.||
hCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase Spur_PTPN13.AA Subfamily.R_Anemone_2.PD 135-391 41 4.2e-78 254.1 In-house 4-261 (262) Show / Hide
Range on Protein: 135-391
Range on HMM: 4-261/262
Sequence Identity: 41% (108 aa)

EEFKTLRQVKAI-DNCEEAKKAQNKDKNRFRNVLPYDKTRVILE---DSGPSDYINASHIKAQVGKDtyEYIACQGPLPNTTQDFWLMVWEQRADVIAMV
||...| ....   ....| .  || |||. |.|.|||||| |.   ..  ||||||..|     |   .|||.|.|||.| .||| ||||| . || |.
eeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkk--ayiatqaPlpetiedfWrmvWeqnsavivml

TMDVESGKVKCHRYWPESANsplMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIH--DDRLPIV
|  .|.||.|.|||||..     . |... | |..  .|... .|.. .  .|..|. .| | ....|||..||. .  || .  ......   .. |||
tqeeergkakvhryWPskgs---rsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpiv

VHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
||||||.||||. |..|..|  |  ..   |...|| ||.||. |.||||||.|.|.. ||||
vhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase Spur_PTPN13.AA Subfamily.N12.PD 145-390 42 2.6e-77 251.2 In-house 20-268 (270) Show / Hide
Range on Protein: 145-390
Range on HMM: 20-268/270
Sequence Identity: 42% (107 aa)

AIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILED---SGPSDYINASHIKAQVGkdTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKC
.. . |...| .|. |||....|||||.||.|.    .  ||||||..||   |  . ||||.|||||.| .||| |.||..  .. |. . || || ||
kvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgveg--kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkC

HRYWPESANSPLmVYNRIEVRLENYQNLDNFSIRRILMIDNEtSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHD-DRLPIVVHCSAGIGRTGT
.|||||. ...|  ....|| ||. ...|.  . | | .... .| ..|.|...  |||| |||.  .||..  ..|.... .  |.|||||||.|||||
eryWpeegeeel-efgefevtleeekavdddflirtLkveaq-kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGt

LITIDAILGLIDRD---EEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEA
.|.|| .  |. ..   ||..| ..|  |||||. ..|||.|| . ||| .| 
iiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase Spur_PTPN13.AA Subfamily.R_Anemone_1.PD 135-391 38 6.4e-76 247.0 In-house 4-257 (258) Show / Hide
Range on Protein: 135-391
Range on HMM: 4-257/258
Sequence Identity: 38% (99 aa)

EEFKTLRQVKAiDNCEEAKKAQNKDKNRFRNVLPYDKTRVILED---SGPSDYINASHIKAQVGKdtYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVT
.||..|.. |. .. | |.||.||.|||. .....|..||.||.      |||||||...|. ..   ..||.|.||..|..||||||.... || |.| 
aefqrlkeike-eekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt--rafiatqapleetvedFWrmvwqekigviVmLt

MDVESGKVKCHRYWPESANSplmvYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRI-HDDRLPIVVH
 .|. | |||.|||.|...    | ...|.|.. ..  .. ||....  ....| ..|.|..| .|||..||...  .|..  ....  . .  |.||||
nliegekkkchqYwPdstek----ygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvh

CSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
|||.||||. . |||.|  . ...   . |.|| .|..|  |.|||.||.|...| |||| 
CsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase Spur_PTPN13.AA Subfamily.R_Sponge_2.PD 148-391 39 1.1e-73 239.5 In-house 16-261 (262) Show / Hide
Range on Protein: 148-391
Range on HMM: 16-261/262
Sequence Identity: 39% (98 aa)

NCEEAKKAQNKDKNRFRNVLPYDKTRVILED--SGPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHRYW
....||. .|. ||||...||||..|| |.   |  |||||||.. .   |    ||| ||||..| .||| ||||..   | |.|.| || ||..||||
slsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgy--krrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYW

PESANSPLMvYNRIEVRLENYQNLDNFSIRRILMIDNETSEVH-HVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDR--LPIVVHCSAGIGRTGTLI
  .   . | ...| |.. ..| .. ||.. . ....|| . .||| .| .||.|.||... .|| .  ...| . .    .|.|.||.|.||||| |..
Pekvdeeve-ygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfi

TIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
|..|  .. .||  | ...|.|| .| |..|...|| |...|.||..  
aldsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase Spur_PTPN13.AA Subfamily.RA.PD 135-389 40 1.8e-71 232.2 In-house 4-263 (266) Show / Hide
Range on Protein: 135-389
Range on HMM: 4-263/266
Sequence Identity: 40% (105 aa)

EEFKTLRQVKAI-DNCEEAKKAQNKDKNRFRNVLPYDKTRVILED---SGPSDYINASHIKAQVGKDtyEYIACQGPLPNTTQDFWLMVWEQRADVIAMV
||||.| .||   .... |.| .||.|||. ..|||| .||||        |||||||.|.    ||  ..||.|||. .| .||| |.|||..| |.| 
eefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekd--kfiaaqGpkeetvedfwrmiweqksativml

TMDVESGKVKCHRYWPESAnspLMVYNRIEVRLENYQNLDNFSIRRILMI---DN-ETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDR--
  | .. ||..|||.     |. |  | | ... . | ....| .|.    |. .  ..  |.|. | .||.  ||...  .|.........     |||
telkerkeekcaqywpdeG---lvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsan

LPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
||||||.|||||.|..||.|  .  ..   | ..|| ||.||  |.||. || |.||. ||    
hpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase Spur_PTPN13.AA Subfamily.N20.PD 136-391 43 2.7e-71 231.7 In-house 5-256 (257) Show / Hide
Range on Protein: 136-391
Range on HMM: 5-256/257
Sequence Identity: 43% (110 aa)

EFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSgpSDYINASHIKAQVGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVE
|| .|   .   . .  ..  |..|||.|..|||| ||| |  |   ||||||.|.     . | ||| |||| .| .||| || |. ..||||.| ..|
efmalelknlpgefnsgnqpsnreknryrdilpydstrvplgks--kdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreie

SGKVKCHRYWPESANSPLMVyNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDrLPIVVHCSAGI
 | .||..||| | . || . ... | ||||| |. | || . .... |   | | |..|. ||||  |...  ....  . |. ||.||||||||||||
ggiikcyhywpislkkplel-khfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshlt-gpmvvhcsagi

GRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
 .. .| ..  | ..  |....||  .|.|| ||.|||.|| |||   || |    
grtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl

Phosphatase Spur_PTPN13.AA Subfamily.N6.PD 134-388 37 1e-70 229.9 In-house 15-291 (295) Show / Hide
Range on Protein: 134-388
Range on HMM: 15-291/295
Sequence Identity: 37% (103 aa)

AEEFKTLR--QVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDS----GPSDYINASHIK--------AQVGK-D--TYEYIACQGPLPNTTQDFW
|||..|   ...   ...|..|..||.|||..|.||.|.|||||.|       ||||||..|.        ... . .  . .||| ||.|..| .||| 
weefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFW

LMVWEQRADVIAMVTMDVESGKVKCHRYWPESANSPLmvYNRIEVRLENYQNLDNFSIRRILMID-NETSEVHHVTQMNFATWPDHSVPSTSLPLLRFAC
|||.. . || |.|..|| || || ||||.. ..    . .|.|.  . .. ... .|....   .. .| ... |..| .||||.||. .  .| |  .
rmvwqensrvivmttkevergknkCarYWPdeetkke--tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfle

HMRRIH---DDRLPIVVHCSAGIGRTGTLITIDAILGLIDR---DEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAAL
... .    .. |||||||||||||||.| ||..| .| .   | .  . ...| .|.||.|..||..||.| |||.  
dvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase Spur_PTPN13.AA Subfamily.RK.PD 135-391 37 5.5e-67 217.3 In-house 4-266 (267) Show / Hide
Range on Protein: 135-391
Range on HMM: 4-266/267
Sequence Identity: 37% (101 aa)

EEFKTLRQVK---AIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILE--DSGPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAM
|||.|| .|      ..|. ||| .|..|||. ..|.||...|.|   |   ||||||. | .   | . ..|. ||||..|..||| .|.....  | |
eefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsy--krpaafivtqgPlqetvkdfWrlvydencasivm

VT-MDVESGKVKCHRYWPESANsplMVYNRIEVRLENYQNLDNFsIRRILMIDN---ETSEVHHVTQMNFATWPDH-SVPSTSLPLLRFACHMRRIHDD-
.| .||| |.||| .|||| ..   . |. |.| | . . . .. . ||. . .     .|.. | |..| .||..  ||     ||..  .. . ... 
lteldvevgrvkClkyWPedte---vrygdikvelveaeldadl-vvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeee

-RLPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
   .|||||.|| ||.|| |.|| .| .|.|..   | |.|| ||...  |..|..||.|.| ..||||
eeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal

Phosphatase Spur_PTPN13.AA Subfamily.N9.PD 135-389 40 8.1e-67 217.1 In-house 4-272 (275) Show / Hide
Range on Protein: 135-389
Range on HMM: 4-272/275
Sequence Identity: 40% (104 aa)

EEFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILE---DSGPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVT
.|.. .|. ..  . . .|.  | .|||. .|| ||.||| |.   ..  ||||||....    |    .|| ||||..|..|||.|||||..|| |.| 
keyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGy--kqkkafiatqGplkktvsdfwrmvweqevlvivmtt

MDVESGKVKCHRYWPESANSpLMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRR------------
 || |..|| .|||.. .|  . .  ..|.  . .. ... .| . . . .|.|  .||   | .|||. |||..  || .  ..|.| .  ||||||||
rvvergrlkcgqywpleees-saefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

--IHDDRLPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
|||||||.||.|  |  ... .  .| . || ||.||  .|||..|| |||.| ||                
skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase Spur_PTPN13.AA Subfamily.N14.PD 136-391 34 1.9e-64 209.1 In-house 5-274 (275) Show / Hide
Range on Protein: 136-391
Range on HMM: 5-274/275
Sequence Identity: 34% (92 aa)

EFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDS--GPSDYINASHIKAQVGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMD
|.  . . ..  ... ||  .|..||||..||||...|| |  .    ..|||||.||..||  ...||..||||..| |||| |||||  ..|.|.| .
eyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee

VESGKVKCHRYWPES-ANSPLMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHM---RRI--------H
 |.|| |...|.|..  .   . ... .|  .  .. | .  . . .    ..|   |  . .. |||| ||.   ..| |  ..||         .. .
eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk

DDRLPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
 |..||||||.|||| ||. | ..  .. .|| .. .... |||||. ..||  || | ||. .. |   
eskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl

Phosphatase Spur_PTPN13.AA Subfamily.RG.PD 135-390 33 4.6e-64 207.9 In-house 4-262 (264) Show / Hide
Range on Protein: 135-390
Range on HMM: 4-262/264
Sequence Identity: 33% (88 aa)

EEFKTLRQVKAID-NCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSGP---SDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMV
|.|. . ..|. | ..| .|| .|| |||  |.......|| |..      .||||||.|.    . . |||. ||||..|..||| |.||..|.| |.|
eqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGy--rrskeyivtqgplketiedFWrmiWehnaqiivml

TMDVESGKVKCHRYWPESANSplMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHH--VTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDD-RLPI
  .|.|. ....|||. ...  . .....|.| . ..|... .|.... .... ....  |.| ....|||...|. .|. | |. .. ...   |||||
tdldekgrrdedvyWPkkdep--lelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPi

VVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEA
.||| ||.||.| .|..|  ... |   |....| .|..|.|...|..||.| |.| ||.   
vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase Spur_PTPN13.AA Subfamily.N5_RR.PD 150-388 34 1.3e-63 206.5 In-house 16-261 (265) Show / Hide
Range on Protein: 150-388
Range on HMM: 16-261/265
Sequence Identity: 34% (82 aa)

EEAKKAQNKDKNRFRNVLPYDKTRVILED----SGPSDYINASHIKAQVGKDTyEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHRYW
|| . . .. |||....|| ...||.||     .  |.|||| .||   ....  |.| ||||||| .|||.|.......|| |.|   |.. ||..|.|
eelevfgsqtknryktilPnensrvllesessededssyinanyikGydeesk-ayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyf

PESANSPL-MVYNRIEVRLENYQNLDNFSIRRILMIDNeTSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDD--R--LPIVVHCSAGIGRTGT
.. .  .   |. .|.. |.  . ...|.|....    ..  ..|. . .. |||| .|    .||..  .... ...|.||||||||||||  |.|.  
Pdaedyeiserygdveikveeiverndysvrklvlkyl-erversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGc

LITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAAL
.  .....   ||.||  || .| ||.||..|| . ..|         
fiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase Spur_PTPN13.AA Subfamily.R_Ecdysozoa.PD 135-389 31 2.9e-63 205.1 In-house 4-266 (269) Show / Hide
Range on Protein: 135-389
Range on HMM: 4-266/269
Sequence Identity: 31% (84 aa)

EEFKTLR-QVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILED---SGPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMV
||...|  ...   ... ..|  |. |||.... ..|||||.|.    .  |||||||.||.   |.. ..|| |.|. .| .||| |..||   .| |.
eeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgy--kekkkfiaaqdPveatigDfWrmiaeqevtlivml

TmDVESGKVKCHRYWPESansPLMVYNRIEVRLENYQNLDNFSIRRILMIDNE---TSEVHHVTQMNFATWP-DHSVPSTSLPLLRFACHMRRIHDD---
. ...  . ||..|||.      . |. | |.| . .. ... || . .  ..     . ..|.| .. .|. |  || ..  ||..  ..| ..     
s-nlteknrkcakyWpie---devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkl

---RLPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
   | ||||||||| ||.|.....| .|  .  ... .....||.||.||. ..|.||.|.|.| ..  
sgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase Spur_PTPN13.AA Subfamily.N_Choan_2.PD 153-389 35 4.5e-63 204.5 In-house 17-263 (266) Show / Hide
Range on Protein: 153-389
Range on HMM: 17-263/266
Sequence Identity: 35% (89 aa)

KKAQNKDKNRFRNVLPYDKTRVILEDS---GPSDYINASHIKAQVGKDTYeYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHRYWPESA
. |.||  ||....||  .|||.||.      . |||| ...   |.... ||| .||||.|...|| |.||...  |.|.|  .||. || ||||....
eyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkk-YiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaep

NSPLMV-YNRIEVRLENyQNLDNFSIRRILMIDNeTSEVHHVTQMNFATWPDHSVPSTSL------PLLRFACHMRRIHD--DR-LPIVVHCSAGIGRTG
. . . .  |.|. .. .. ....|.. | . .  .|.....   . |||||.||...        ||.   ..||...  |.  |..||||||.|||||
kekvkladgkikvlals-eekeegyiltrlrlek-kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtG

TLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
||.|| .. |......  ||.|.. |||.|  ..|. .|| . ||| .| 
tliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve

Phosphatase Spur_PTPN13.AA Subfamily.N1.PD 147-390 36 1.5e-62 203.1 In-house 18-266 (268) Show / Hide
Range on Protein: 147-390
Range on HMM: 18-266/268
Sequence Identity: 36% (92 aa)

DNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSgPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHRYWP
...|||. .|...||.|.| |||..|..||..   |||||| ....  .   .||  |||||.|.. || ||||| .  . |.   || ...||. |||.
letreaklpenrglnryrdvspydhsriklera-dvdyinaslvele--eakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp

ESANSPLMVYNRIEVRLE--NYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRR---IHDDRLPIVVHCSAGIGRTGTL
  ... ....... ...    .. ..|  | . . | ||.|.. ...  ..|||| .||..   .|.|  ..|.   . .|  |.|.||||||||.||| 
qeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtl

ITIDAILGLIDRDEEFKVLNIVKG---LRKQRQGMIQTKDQYIFCYKAALEA
 .|..| .|.. .. . ..| |    |||.| |.||| ||  | | | ||  
slvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg

Phosphatase Spur_PTPN13.AA Subfamily.N23.PD 142-390 31 8.9e-58 187.5 In-house 94-348 (350) Show / Hide
Range on Protein: 142-390
Range on HMM: 94-348/350
Sequence Identity: 31% (78 aa)

QVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRvilEDSGPSDYINASHIKaQVGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKC
|.. ...    .. ...|.   .|... ...    . .  .|||||...| ..   . ..|| |||...|  |||||||||.. || |.| .|| .| ||
qprhlqtegsGqqqgtpdsrhdpnrvklqqst---qpgqqddyinatylk-eltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkc

HRYWPESANSPlMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIH----------DDRLPIVVHC
..|||.  . . .... ..| |.. .. .... | . .  |..| |..|..... ||... ||.    ||.|   .. ...   ||..|||||.|||||.
dqYwPideget-nlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhC

SAGIGRTGTLITI-DAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEA
  .  ||  |  ..    ....|. ||.||. |.|.|... ..|.| |||          
saGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase Spur_PTPN13.AA Subfamily.RN.PD 136-389 39 2e-55 179.4 In-house 5-261 (264) Show / Hide
Range on Protein: 136-389
Range on HMM: 5-261/264
Sequence Identity: 39% (102 aa)

EFKTLRQVKAIDNCE-EAKKAQNKDKNRFRNVLPYDKTRVILEDS---GPSDYINASHIKAQVGKDTyEYIACQGPLPNTTQDFWLMVWEQRADVIAMVT
|...| . .| ....  ||. .| .||| ..|||||..|| |...     ||||||| |  .  . .  |||.||||..|  ||| ||||| .|| ..| 
ewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprap-ayiatqgplsstiadfwqmvweqGvvvivnlt

MDVESGKVKCHRYWPESANSplmVYNRIEVRLE-NYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHDDR-LPIVV
  |.|  .|.||||.  ..   ||.  ||.|  ..   |.. .| . . . .|||   |||. | .||...||... .|| |   .. .  |  ||||||
rleeegvkqckrywpdeGse---vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivv

HCSAGIGRTGTLITIDAILGLIDRD-EEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
|.| ||||. | || .|  . .   |  .   .. || ||.|...||||. |...|  |  
hcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae

Phosphatase Spur_PTPN13.AA Subfamily.N_Nematode_1.PD 135-389 32 1e-54 177.2 In-house 4-262 (265) Show / Hide
Range on Protein: 135-389
Range on HMM: 4-262/265
Sequence Identity: 32% (85 aa)

EEFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVIL-EDSGPSDYINASHIKAQVGKdtYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMD
.||..|.. .  .. .  |.||..||||...|   ||.||.| |.. ||||| | .. . .      .| .|.|| .|..|||||  .. . | |.   .
defralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnp--krficaqaPldktiadfwymvlqekveaivmlckl

VESGKVKCHRYWPESANSPLMVYNR---IEV----RLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFachMRRIHDDRLP
| ||.||. |.| . .. | . ..   | |    . .. .. ...     | ..   .....||....  |||. ||.. |  | .   . ... .. ||
iekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalel---leavrgskgP

IVVHCSAGIGRTGTLITIDAILGLIDRDEEF-KVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
|||||||||||||...|. ||  .  ...  .. ..|| .|.||.  |||||.| ..  |.   
ivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln

Phosphatase Spur_PTPN13.AA Subfamily.RC.PD 136-389 30 1.3e-52 170.5 In-house 5-285 (288) Show / Hide
Range on Protein: 136-389
Range on HMM: 5-285/288
Sequence Identity: 30% (88 aa)

EFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVIL----------------------EDSGPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQ
||..| .|..    ..|.| .||.|||. .|||||  || |                      .   .|.|||||.|..   |.   ||| |||| .| .
efqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsy--kkpekyiaaqGplketvd

DFWLMVWEQRADVIAMVTMDVESGKVKCHRYWPESANsplmVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRF
||| |..|... || |.|   |  . || .|| |  .     |  .|| |.. ..  .. .|.. . ..   .  .|||.....|....|     ||.. 
dfwrmiferkvkvivmltelkeGdrekcaeyweeGkr----ayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkl

-------ACHMRRI----HDDRLPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
        . |.     .    |..|||..| .|||. |...|.|  .. .|   | ..|| |||.| .|.....|||. |..  | 
iqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve

Phosphatase Spur_PTPN13.AA Subfamily.N_Nematode_4.PD 141-388 31 2.1e-52 169.6 In-house 10-260 (264) Show / Hide
Range on Protein: 141-388
Range on HMM: 10-260/264
Sequence Identity: 31% (80 aa)

RQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSGP-SDYINASHIKAQvgkDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKV
.. ||  |.      .|.||||....|  |.|||.|..  |  ||| || ..     | ..||..||||..| .||| ||..... |. |.   .| |  
vkgkappnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP---dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegve

KCHRYWPESANSPlMVYNRIEV-----RLENYQ--NLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRiHDDRLPIVVHCS
|| ||.||  .   ... . ..     . | .    |. . .  .    . .||   |  ...  |.|.  | .. |....   ..  ..   |||||||
kcaryypeksekv-vkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk-kkkekPivvhcs

AGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAAL
||.||| ||. ||     |    | .||.||. ||. |.. .|.. |..| ..   
aGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvli

Phosphatase Spur_PTPN13.AA Subfamily.R_Nematode_2.PD 147-388 30 5e-48 155.2 In-house 19-257 (261) Show / Hide
Range on Protein: 147-388
Range on HMM: 19-257/261
Sequence Identity: 30% (72 aa)

DNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSGPSDYINASHIKAqvGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHRYWP
.. .|  .  .|||.|. .|   ..|.|     |    | | ..     ...  .|| |||| ||..||| ||  .  . | |..  ||. | ||..|.|
esvtesaaylpkdkhRypdvPCkpetavevivdgkrvpihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfp

ESANSPLMVYnRIEVRLENYQNLDNFSI-RRILMIDNETS--EVHHVTQMNFATWPDHSVPSTSLPLLrfaCHMRRIHDDRLPIVVHCSAGIGRTGTLIT
 . .. | .  |....  . ... . .| .| | ....|   . . || . .. |||. || . . |.  ..... |||||||||||||...|... .  
letsqkldlg-rfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf---eLlelvkksekPivvhCsaGiGRtmafig

IDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAAL
 .  |.. .. . .| ||..|.  |||. |. .   .||      
teylareveadptieltealkelrehRwkgiqtesqlywltlgal

Phosphatase Spur_PTPN13.AA Subfamily.N_Nematode_6.PD 153-391 32 1e-44 144.5 In-house 20-252 (253) Show / Hide
Range on Protein: 153-391
Range on HMM: 20-252/253
Sequence Identity: 32% (75 aa)

KKAQNKDKNRFRNVLPYDKTRVILEDSgPSDYINASHIKAQvgKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHRYWPESANSP
..||.||..|.  .| .|. |.|  .  || |. .| .  ...  .| .|.|| .| ..|| |.  .  . | |.   ||.|| |. .| ..       .
aflkfkdrnrytniqCcdagrlkladd-edfyihanlvkis--tkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGda

LMVYNRIEVRLENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRrihDDRLPIVVHCSAGIGRTGTLITIDAILGLID
 .  .|  .. .. |    | .. |  .. |   |  ...| |||| || . |  ||.   ...|. |||||||||.||||||. |  ||  .   .   
rkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvk---kdkkPivvhCsaGvGrtGtlaliliilealr

RDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALEAL
| ...  ||..|   .||. ||.. ..  || |      
lpdfqgvkdllvklreerfravqtevqylyalrcvleyl

Phosphatase Spur_PTPN13.AA Subfamily.N_Nematode_5.PD 135-389 24 1.5e-42 137.2 In-house 4-255 (258) Show / Hide
Range on Protein: 135-389
Range on HMM: 4-255/258
Sequence Identity: 24% (63 aa)

EEFKTLRQVKaIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDSGpSDYINASHIKAQVGKDtyEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDV
.||..| ..| .....  .  .|..|||  .|  .|.|||.|.|   ..|||||.|| .  .   ..|  | |||.|..||| || ...   . ....| 
tefeklaslk-pnketckafeknlkknrskdvkilDetrVkltded-dsYinaskiklddlek--kliltQlPlpdteedFWrmvyqekitsvvllvede

ESGKVKChRYWPESANSpLMVYNRIEVRLENYQNLDNF-SIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACH--MRRIHDDRLPIVVHC
|  . ..  ..|.....  . .. . ..  . .. ..  .   .  . .. || . ..  ...||....||. . .....| .  ..   ..  |.||..
elketav-sffpletgd-ylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvs

SAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAALE
..|.||.||.......   .....|... .|.| .|.|| |.... .|| .|.|.|. 
dlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavld

Phosphatase Spur_PTPN13.AA PTPc_motif 289-389 42 5.5e-40 140.08 SMART 1-92 (92) Show / Hide
Range on Protein: 289-389
Range on HMM: 1-92/92
Sequence Identity: 42% (45 aa)

HVTQMNFATWPDH-----SVPSTSLPLLRFACHMRRIHDDRLPIVVHCSAGIGRTGTLITIDAILGLIDRDEEFKVLNIVKGLRKQRQGMIQTKDQYIFC
 |... . .||||     .||.   ..|.|  |.|       |||||||||.|||||...|| .. .      . ....|| .|||| ||.||..|||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFC

YKAALE
|.. ||
YRCILE

Phosphatase Spur_PTPN13.AA Subfamily.R_Nematode_3.PD 141-388 23 1.4e-38 124.3 In-house 10-263 (267) Show / Hide
Range on Protein: 141-388
Range on HMM: 10-263/267
Sequence Identity: 23% (62 aa)

RQVKAIDNCEEAkkaQNKDKNRFRNVLPYDKTRVILED---SGPSDYINASHIKAQvgkDTYEYIACQGPL--------PNTTQDFWLMVWEQRADVIAM
....  .. ..    .. ...|  .|. . ||||.|..      .|.|.|. .. .   .  . |  |.|.         .| .|| |. .... ...|.
aklakknatsls---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecp---nglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvm

VTMDVE---SGKVKCHRYWPESANSPlMVYNRIEVRL-ENYQNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDHSVPSTSLPLLRFACHMRRIHddrL
   ||   ... || .|.||...   .  ....|.  .. ..|...  .| |..  |  . . || ..  |.....| .. ..|  .  ..       |.
lcdfveedgeeeekcseYypekvdge-lkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveksk---t

PIVVHCSAGIGRTGTLITIDAILGLIDRDE-EFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAAL
|||||.||.|..||  |.    || . . ....|...| |||||.| |||. ...|     |  
pvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgil

Phosphatase Spur_PTPN13.AA Subfamily.N_Nematode_egg.PD 136-387 26 1.5e-28 91.5 In-house 5-252 (257) Show / Hide
Range on Protein: 136-387
Range on HMM: 5-252/257
Sequence Identity: 26% (68 aa)

EFKTLRQVKAIDNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDS-G--PSDYINASHIKAQVgkDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTM
.|. | ..    . ..| ......| | . |   . .|| ||   |    |.| | ..| .      |.| .| || || .||| ||.... . | |.| 
rfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkp--llnefilaqaplkntvedfwrmvfqekvqyivmlts

DVESgkVKCHRYWPESANSPLMV---YNRIEVrLENYQNLDN-FSIRRILMIDNETSEVhHVTQMNFaTWPDHSvpSTSLPLlRFachMRRIHDDRLPIV
 .||   .|. ||| . . .|..     |||  |. ... |  | . .. ..  .  |  ...   .   |      || |    .|.. .   |.||..
akes--erceyywpkaeseslvtvpGslrien-lkvdskadplfrvtklklvGgddeel-flehwqg-dvnyls--dvyspl-rv---lrklrnlskpvv

VHCSAGIGRTGTLITIDA-ILGLIdRD--EEFKVLNIVKGLRKQRQGMIQTKDQYIFCYKAA
  |. ...||..|.  .| |. |     . ||. |. ||..|....  .|.| |.       
vqdilGvskaatlvaieiallsll-rGpitkslvlravvflrlrrrlsvesvllylfvyrlv

Phosphatase Spur_PTPN13.AA Subfamily.N_Fungi_PTP1.PD 156-272 32 1.8e-26 84.5 In-house 44-173 (343) Show / Hide
Range on Protein: 156-272
Range on HMM: 44-173/343
Sequence Identity: 32% (41 aa)

QNKDKNRFRNVLPYDKTRVILE-----------DSGPSDYINASHIKAQ----VGKDTYEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVK
.   |||..|.|||...||.|.              ..|||||...| .      .  . ||| |.|||.| .||. .. .|| ..| ||| .  ||.||
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek

CHRYWPESANSPLMVynRIEVRLENYQNLDNF
|.| . .   |  ... . ||  . ..     
cyrYWqegsydditv--klaskwenimginds

Phosphatase Spur_PTPN13.AA Subfamily.N_Fungi_PTP1.PD 267-388 29 8.1e-21 65.9 In-house 192-339 (343) Show / Hide
Range on Protein: 267-388
Range on HMM: 192-339/343
Sequence Identity: 29% (44 aa)

QNLDNFSIRRILMIDNETSEVHHVTQMNFATWPDH---SVPSTSLPLLR--------FACHMRRIHDDRLPIVVHCSAGIGRTGTLITIDAILG------
.. |.        ..   ||.. | |...  |.|      |   |. |           ..     .   ||.||||||.||||||.|.| .|       
ddndlnnnndltpvtaavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeile

-LIDRDEEFK--------VLNIVKGLRKQRQGMIQTKDQYIFCYKAAL
 | .. .. .        .  ||. |||||  |.|..||.||.|.|.|
nltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall

Phosphatase Spur_PTPN13.AA Subfamily.N_Nematode_eak.PD 147-305 25 9.5e-18 56.0 In-house 16-171 (281) Show / Hide
Range on Protein: 147-305
Range on HMM: 16-171/281
Sequence Identity: 25% (41 aa)

DNCEEAKKAQNKDKNRFRNVLPYDKTRVILEDS--GPSDYINASHIK-AQVGKdtyEYIACQGPLPNTTQDFWLMVWEQRADVIAMVTMDVESGKVKCHR
..... .. ..||  ...|.|.  | |  |   .  ||||| .. ..||.   .||    .  .    || || ||..| ..  ||| .  |  .|.|. 
lsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGr---kyiltGiasedkvfafwqmvleqkspaivqlledveekleksdk

YWPESAnsPLMVYNRIEVRLENY-QNLDNFSIRRI-LMIDNETSEVHHVTqmnFATWPDHSVPS
.    . |  ..|   .|  . ...  | . |   ||| .|.| .   .  | . ..|      
yfpdkt--evlkyGildverkeyavkrniletrllilrkGnethrvlhyk---vfGwtettlpk

Phosphatase Spur_PTPN13.AA Family.DSP.PD 264-386 19 2.6e-10 31.7 In-house 123-242 (387) Show / Hide
Range on Protein: 264-386
Range on HMM: 123-242/387
Sequence Identity: 19% (24 aa)

ENYQNLDNFSIRRILMIDNETSEV---HHVTQMNFaTWPDHSVPSTSLPLLRFACHMRRIHDDRLPIVVHCSAGIGRTGTLITIDAILGlidrdEEFKVL
.| ..| .  . .|. .  . ..    .... ...  ..||..|. .. . ..   .   .|..  ..||| ||.||.|||| .  .       |..   
knlewlkelgvtkivnltddkpqftkelgikylri-pidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliiaYlmks-----egltle

NIVKGLRKQRQGMIQTKDQYIFCYKA
 .. .|..|.|.|. .....  .|. 
ealdwvrskRpgvitpnqgflkqlkd

Phosphatase Spur_PTPN13.AA Subfamily.PTPDC1.PD 288-383 27 2.4e-09 28.5 In-house 133-220 (229) Show / Hide
Range on Protein: 288-383
Range on HMM: 133-220/229
Sequence Identity: 27% (26 aa)

HHVTQMNFAtWPDHSVPSTSLpLLRFACHMRRIHdDRLPIVVHCSAGIGRTGTLITidAILGLidrDEEFKVLNIVKGLRKQRQGMIQTKDQYIFC
. .. .||. ..|..|.|    .|     .         | ||| || |||| ||.  ..|      ....  . .| .|..|   |||..|  ..
qgiyfynfg-lkDygvasler-iLdivkvvdfal-eegkiavHCHAGlGRtGvlia--cylvy---akrltaeeaiklvrskrpksiqtreqvelv

Phosphatase Spur_PTPN13.AA Subfamily.DSP23.PD 266-379 24 7.1e-09 27.4 In-house 6-116 (128) Show / Hide
Range on Protein: 266-379
Range on HMM: 6-116/128
Sequence Identity: 24% (28 aa)

YQNLDNFSIRRILMIDNETSEVHHVTQ---MNFATWPDHSVPSTSlPLLRFACHMRRIHDDRLPIVVHCSAGIGRTGTLITIDailgLIdRDEEFKVLNI
.| | .  || .. . .|..  .....   ..    ||.  |.    . |.   .   ..   .. |||  |.||||||..      |. .|..   . .
vqfladqGirvlvslttegapyseaapsltlrridipdfcPPale-qvarlvriveeaekkeeavgvhcalGlGrtGtllacy----lv-keeglaadda

VKGLRKQRQGMIQTKDQ
  .||.|.| |.|..| 
iaevrkrrkGsietveq

Phosphatase Spur_PTPN13.AA Subfamily.PTEN.PD 263-343 25 2e-07 22.3 In-house 35-113 (305) Show / Hide
Range on Protein: 263-343
Range on HMM: 35-113/305
Sequence Identity: 25% (21 aa)

LENYQNLDNFSIRRILMIDNETSEVHHVTQMNFAtwpDHSVPSTSLpLLRFACHMRR--IHDDRLPIVVHCSAGIGRTGTLIT
|  |..  .. |  .    ...   ..|... |    ||  |. .| | ..  .. .   .|..  ..||| || ||||..|.
ltvykgkgklrilnargekedsdfdgrvavypfd---DhnpptleL-leeivedvdkwLkedksnVvavHCkaGkGRtGvmic

Phosphatase Spur_PTPN13.AA Subfamily.CDC14.PD 325-379 37 4.6e-07 21.3 In-house 199-248 (258) Show / Hide
Range on Protein: 325-379
Range on HMM: 199-248/258
Sequence Identity: 37% (20 aa)

LPIVVHCSAGIGRTGTLITIDAIlglidRDEEFKVLNIVKGLRKQRQGMIQTKDQ
|.||| ||.|||||||.   |     .  .|.  ...  ||  | |.. .. |  
GaiavhCkaGLGrtgtligcyli-----khyrftaaetiawlriarPGsvigpqq

Phosphatase Spur_PTPN13.AA Subfamily.PRL.PD 316-385 26 5e-07 21.2 In-house 73-137 (140) Show / Hide
Range on Protein: 316-385
Range on HMM: 73-137/140
Sequence Identity: 26% (19 aa)

HMRRIHDDRLPIVVHCSAGIGRTGTLITIdailGLIdrDEEFKVLNIVKGLRKQRQGMIQTKD-QYIFCYK
...  ...   . ||| ||.||.  |...     ||  .. .|  . |. .|..|.| | .|  ...  ||
kekfkeepkstvavhcvaGlGraPvlval----ali--eaGmkyedavefirekrrgainskqlkflekyk

Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPN13.AA Protein None 396 None Fasta, JSON
Spur_PTPN13.NA RNA None 1188 None Fasta, JSON
Spur_PTPN13.AA.PD_132-392 Protein Phosphatase Domain None 261 None Fasta, JSON