Spur_PTPN14
Species: S.purpuratus
Alias: Spur_hmm24405, Spur_PTPN14, hmm12219
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N14
Protein domain

Protein domains of Spur_PTPN14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FERM Spur_PTPN14.AA B41 17-222 25 2.4e-51 177.83 SMART 1-232 (232) Show / Hide
Range on Protein: 17-222
Range on HMM: 1-232/232
Sequence Identity: 25% (58 aa)

GKNSFVARIQLLDSAVLEITLTPESLGQDCLDTIAQKLQL--EENIYFGLQYSNKNYKLRWVDLEKPLKKQLDK--NAHDSMLRLGVMLYTTN----IQT
 .  ...|....|. .||... ... ||| .|...... .   |  ||||.| ... . .| |..|...||  |  . .   | . | .|...      .
SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCGISPREHWYFGLWYEDPHEDRHWLDHWKTIMKQDVKWHKSEPWTLHFRVKFYPPDWHGFPNQ

LRHEMTRY-MYFLQLKSDFIEGILPCN-EEQAVTLASFALQAEIGNSDPA-------KHTVEFYQNEYVLLPKNMTTENVS--------LSELLLKVMNA
|... |||  ..||...|...| .||. || .. ||....|.| |. ||        .. |. |  .. .||| .  . .         . |.  ..|..
LQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQWIDSIKQSFMHYQMHHKEWRKRIMEW

HQAKVGMSTCQSELGYIEQAAKLQ-GYGQESF
|.  .||.. ...| |.... ..  .|| | |
HKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF

FERM Spur_PTPN14.AA FERM_M 105-222 19 3.2e-27 94.7 Pfam 1-171 (171) Show / Hide
Range on Protein: 105-222
Range on HMM: 1-171/171
Sequence Identity: 19% (33 aa)

NIQT-LRHEMTRYMYFLQLKSDFIEGILPCNEEQAVTLASFALQAEIG-NSD-PAKHTVEF-YQNE------------------YVLLP-----------
.... ...| ||. ..||.|.| .|| .|| ||.|. ||. ..|.|.| ... |.||.. . .. .                  . ..|           
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT

-------------------KNMTTENVSLSELLLKVMNAHQAKVGM-STCQSELGYIEQAAKLQGYGQESF
                        .   ....  ... .|..  || |  . .| ||. . ....|| . |
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF

FERM Spur_PTPN14.AA FERM_N 25-103 29 7.3e-22 81.11 Pfam 1-93 (93) Show / Hide
Range on Protein: 25-103
Range on HMM: 1-93/93
Sequence Identity: 29% (27 aa)

IQLLDSAVLEITLTPESLGQDCLDTIAQKLQLEENIYFGLQY----SNK--NYKLRWVDLEKPLKKQLDK--------NAHDSMLRLGVMLYT
..|||. .||.|. ... ||...|...|.| ..|  |||||.      |  | ...|.|..|...||...        .  .  |.. |. | 
VHLLDDTQLECTCDKKTTGQELFDQVCQHLNIRECWYFGLQFCKQNDKKEGNQHMHWLDPDKKICKQMKDGWKHKIKKKCPPCTLFFRVKFYP

FERM_C Spur_PTPN14.AA FERM_C 226-305 19 9.6e-12 44.09 Pfam 1-92 (99) Show / Hide
Range on Protein: 226-305
Range on HMM: 1-92/99
Sequence Identity: 19% (18 aa)

DDSGNE-LFISASFSGLSVK--HLNRQET--VHFEWHEVVSMGHNRRAFGVGT-------SRSHDVLQFQMEDAETAKYVCRICRLQQQFHK
| .|.. ...  . .|. |   . |.. |  ..| | |.. . ..|. | .         . . ....|.|......||... |. . ||..
DKKGTDTWWLGVCAKGINVYQVQDNNKITPMNTFPWPEIRKISFKRKKFFIKLRDDPDEGEKYEHTHTFYMPNYRACKYLWKCCVEHHQFFR

Phosphatase Spur_PTPN14.AA Subfamily.N14.PD 1040-1313 64 3.1e-143 467.1 In-house 1-275 (275) Show / Hide
Range on Protein: 1040-1313
Range on HMM: 1-275/275
Sequence Identity: 64% (177 aa)

QVFTEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNSGGYINASRVKVPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAM
.||||||.|.|||| |...|.|||||...|||||||||||.|||||....|| ||||||..||.|.|. ..||.||||.|.||||.|.||||.|.|.|.|
kvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivm

LTKLKEDGKEKCFKYWPDCTSpKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRHANSM
||. .||||||.|||.|...| ||.|.||| |.|...||.||...||.||.|.|.||.|.||||||||.|||..|.|.||.||||||||.|||.|..||.
lteeeedgkeksfkylPkles-kkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnse

NE--VEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSLK
.|   |. || .|||||||||||||.|.|..|..|||||||.|.|....||.||||.|||..||.||||.||..||
vesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikylk

Phosphatase Spur_PTPN14.AA PTPc 1040-1313 27 2.8e-100 340.38 SMART 1-308 (308) Show / Hide
Range on Protein: 1040-1313
Range on HMM: 1-308/308
Sequence Identity: 27% (89 aa)

QVFTEYEQITKKREGA---------VCYTSKLPENV--SRNRFK-DVLPYEDCRVELSSSHH-----NSGGYINASRVKVPVAGELLHYIAAQGPMENTV
....|.| . . . .           | ....|||.  ..||.| |...|...|| |.. ..     ....||||. ....  ..   ||..|||...|.
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI

QDWWRMVWESGTQVIAMLTKLKED--------GKEKCFKYWPDCTSPKKNTAEFGPFRVIAQFSNDSG-CYITSGLTLRHVPS--------GEQRTVWHL
 | |||||. ....|.||... |         |.||| .||||       . ..| ..|  .  .    .|..  .....           .| |||.|.
EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE------PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHY

QYNDWPNQGCPDDVHGFLSFLEEFQSVCRHA--NSMNEVEV------------GPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQR
.| .|| .|.|.. ..||.|.... .. .|   ..||                 .|..||||||.||||.....|||. ..|.   ..|....  .|.||
HYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMN---MVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQR

MLMVQTVGQYTFVYKALIQSLK
. ||||  || |.|..... .|
PGMVQTEEQYIFCYRCILEYIK

Phosphatase Spur_PTPN14.AA Y_phosphatase 1065-1310 33 1e-94 325.79 Pfam 1-243 (243) Show / Hide
Range on Protein: 1065-1310
Range on HMM: 1-243/243
Sequence Identity: 33% (84 aa)

NVSRNRFKDVLPYEDCRVELSSS-HHNSGGYINASRVKVPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGK-EK-CFKYWPDCTSP
| ..||.||...|...|| |..   .... ||||. ... . ..   ||..||||..|. | |||||. ....|.||... |.|. || | .||||  . 
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPD--NK

KKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPS--GEQRTVWHLQYNDWPNQGCPDD-VHGFLSFLEEFQSVCRHANSMNEVEVGPPPIVHCSAGVGR
.  . ..|.|.|  .  .   .|..  .....  .  .| |||.|..| .|| .|.|.. ....|.|....... .  |...     ||..||||||.||
EGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP--NPDHGC---PPIVVHCSAGCGR

TGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
||.. ..|||. ..||.....|...   .|.||. ||||  || |.|.....
TGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Spur_PTPN14.AA Subfamily.N3.PD 1041-1310 36 1.7e-78 254.6 In-house 2-258 (261) Show / Hide
Range on Protein: 1041-1310
Range on HMM: 2-258/261
Sequence Identity: 36% (98 aa)

VFTEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHnsgGYINASRVKVPVAG--ELLHYIAAQGPMENTVQDWWRMVWESGTQVIA
| ...|.. .|..|  . ....|||...||..|.|||.. ||.|..|.     ||||. |.. . .     .|||.|||...|..|.|.||||  ...| 
vlaqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset---dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstliv

MLTKLKEDGKEKCFKYWPDctspKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCrhans
||| | |.|. || .|||.    .... ||| |.|  . .. .  |..  |.|..  . |.|.. .||| .||..| ||| . ||.|.|. ...      
mlttlverGrvkChqyWPe----tedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr-----

mneVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
       .| .||||||.||||||.|... .. .|..|........  .|.||. .||||.||.|| .|...
---sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk

Phosphatase Spur_PTPN14.AA Subfamily.N13.PD 1043-1313 37 4.9e-69 223.9 In-house 4-259 (259) Show / Hide
Range on Protein: 1043-1313
Range on HMM: 4-259/259
Sequence Identity: 37% (101 aa)

TEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSshhnSGGYINASRVKVPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTK
|.... . .    | ..|  || ..||...||||.. ||.|..    .||||||| .||||  .  .|||.|||. .||.| |.||||..||||.|. ||
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgd----eggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtl

LKEDGKEKCFKYWPDCTSpkKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRHANsmnev
.|| || .|||. ..  |..   . ..|     ..   .  . |..... ||| | | ||.. .||. | |     ..|. | ... ..|          
ekekgkvkchrywPerkn--kklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdag-----

evgpPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSLK
| .||||||.||.|||. .|...  .|...|... ...  ||.||  .|||  || |||||... ||    
----PivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk

Phosphatase Spur_PTPN14.AA Subfamily.R_Anemone_2.PD 1041-1312 32 4.1e-65 211.1 In-house 2-261 (262) Show / Hide
Range on Protein: 1041-1312
Range on HMM: 2-261/262
Sequence Identity: 32% (87 aa)

VFTEYEQITKKREG-AVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNSG-GYINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIA
...|||......|    . ..  | |  .||. ..|.|...||.|.  . . |  ||||. .      .   |||.|.|. .|..|.|||||| ...|| 
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidG--yrrkkayiatqaPlpetiedfWrmvWeqnsaviv

MLTKLKEDGKEKCFKYWPDctspkKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVcrhans
|||...| || |. .|||.     |.. ..|  .| .. . ... |.   .....  . |.|.|.| .||..| |... ..|... . ...       ..
mltqeeergkakvhryWPs-----kgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqveka------

mNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSL
 .   | .|||||||||||| . |||..  ..... ... ...  ||.|| |||||  ||.|.|..|.. |   
-qqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase Spur_PTPN14.AA Subfamily.N9.PD 1042-1310 34 1.3e-64 209.5 In-house 3-272 (275) Show / Hide
Range on Protein: 1042-1310
Range on HMM: 3-272/275
Sequence Identity: 34% (94 aa)

FTEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSS-HHNSGGYINASRVKVPVagELLHYIAAQGPMENTVQDWWRMVWESGTQVIAML
||..| ..      ..|||. |...||..||| |.. || |..  ....  ||||. |.     .   .||.|||...||.|.||||||.. || | |..
skeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGyk--qkkafiatqGplkktvsdfwrmvweqevlvivmt

TKLKEDGKEKCFKYWPDCtspKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSV-----CRH
 | |. || .|||.    ....|||| ..|     . .  | .. |....| ..|.|.| | |.  ||. | |.. . .|.||. ..         ... 
trvvergrlkcgqywple---eessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkel

ANSMNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
.    ||| .||||||.|||| .  .|| .. ||. . ... . .  ||.||  ..||  ||.| |.|...    
gdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase Spur_PTPN14.AA Subfamily.R_Sponge_2.PD 1044-1310 35 1.4e-64 209.2 In-house 5-259 (262) Show / Hide
Range on Protein: 1044-1310
Range on HMM: 5-259/262
Sequence Identity: 35% (94 aa)

EYEQItKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNSGGYINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKL
|.... .|..   ....||.|||..||||..|||.. ||.|...... . ||||| | .    .   |||.|||...||.|.||||||  .. | |||.|
eeksv-eketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdg--ykrrkayiatqgPlketveDfWRmvweykvstivmltnl

KEDGKEKCFKYWPDCTspkKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPS-GEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSvcRHANSMNEv
.|.||||| ||||. .   ....|.| |.|  . .. .  ||.  |.| .  | .....| . ..  ||....|.|   .|..... .    . .| |. 
eengkekcakYWPekv---deeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlr--aqkksgnk-

evgpPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
    . .|.||.||||||  . .|.... |...|||.. ...  || .|. .||.. || |...|| .
----aitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalle

Phosphatase Spur_PTPN14.AA Subfamily.N_Choan_2.PD 1059-1311 36 4.2e-64 207.4 In-house 12-264 (266) Show / Hide
Range on Protein: 1059-1311
Range on HMM: 12-264/266
Sequence Identity: 36% (93 aa)

TSKLPENVSR---NRFKDVLPYEDCRVELSSSHHNS-GGYINASRVKvPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKY
....|| ..    ||..|.||    || |.. ...|   ||||  |.  . ||  .||||.||...|....|||.||. .. |.|.|.|.|.|..|| .|
eeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvr-GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerY

WPDcTSPKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHvpSGEQRTVWHLQYNDWPNQGCPDDVHGFLS---FLEEFQSVCRHAnsmNEVEVGPPPIVH
||   . .| . . |  .|.|. .. .  ||.  |.|..  .||.|.. | .||.||..| | .  . |||. .. | |.    .|.. . | .||||||
Wpa-epkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvr---keldkaePllvH

CSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQS
|||||.|...||..  ||....... ...  ||..|| .||.. ||...|||...     
csaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase Spur_PTPN14.AA Subfamily.RB.PD 1043-1312 32 7e-64 206.9 In-house 4-260 (261) Show / Hide
Range on Protein: 1043-1312
Range on HMM: 4-260/261
Sequence Identity: 32% (87 aa)

TEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHN-SGGYINASRVkvPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLT
|||...|  .   . ......|  .|||. .|||.  ||.|.. ... .  ||||. .  |      .|||.|||...||.| ||||||....| |||.|
eeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyi--pgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

KLKEDGKEKCFKYWPDctspKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHvpSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRHANSMNe
 | ||||| .|||.    ....  .|  .|  . ...   ...  .....    |.|.| ....  ||. | |.. .  |.|......  ... |..   
qlvEkgkekceeYWPa----deepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskk-

vevgpPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSL
   | .|||||||||||. . .| .. ..|.|. ...  ..  ||..|.|.|||  || |....|.. |  
-----PivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase Spur_PTPN14.AA Subfamily.N6.PD 1041-1310 32 2e-63 205.6 In-house 14-292 (295) Show / Hide
Range on Protein: 1041-1310
Range on HMM: 14-292/295
Sequence Identity: 32% (92 aa)

VFTEYEQIT--KKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNSGG--YINASRVKVPV--------AG---ELLHYIAAQGPMENTVQDW
. .|.|...  . ..   .  .. .|| . ||.|..||... || |.  ...  |  ||||. ...|          .   .  .|||.||....||.|.
fweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdF

WRMVWESGTQVIAMLTKLKEDGKEKCFKYWPDctspKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHV-PSGEQRTVWHLQYNDWPNQGCPDDVHGFLS
|||||.  ..|| |.||  | ||.|| .||||    .... |.|  .|     .    |.   ... |     |.|........||..|.| |   .|.|
WrmvwqensrvivmttkevergknkCarYWPd----eetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvln

FLEEFQSVCRHAnsmnevEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHN---EEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
||. ..  ..       |   | .||||||.|||| ....||... .|..    .|.| |..  .|.||  .||||| |||||. .   
fledvnkkqeel------ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf

Phosphatase Spur_PTPN14.AA Subfamily.N_Choan_1.PD 1043-1312 33 1.2e-62 202.8 In-house 4-261 (262) Show / Hide
Range on Protein: 1043-1312
Range on HMM: 4-261/262
Sequence Identity: 33% (92 aa)

TEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSS-HHNSGGYINASRVKVpVAGElLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLT
.|||....   . ..  || .||| .||....  |.  ||... . ....  ||||. |.  . ||  .|||.|||. ......|.||||   ..|.|.|
eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpg-ykge-keyiatqgPvPaslvsfWqmvweqkvsaivmvt

KLKEDGKEKCFKYWPDCTSpkknTAEFGPFRVIAQFSNDSGCYITSGLTLrHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRHANSmne
.  | || || .|||| .|    . ..| ..|  . ....  ||.  ..| .  |||.|.| .|.|  ||..| |.. . .|.| .. ... .. .    
reieagklkChryWPdens----elklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk---

vevgPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEI-NIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSL
     | ..||||||||||. . .| .....|...|  ..  ..  ||..|.|||||. ||.|||||. . |
----aplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase Spur_PTPN14.AA Subfamily.N12.PD 1057-1311 35 1.4e-62 202.5 In-house 24-268 (270) Show / Hide
Range on Protein: 1057-1311
Range on HMM: 24-268/270
Sequence Identity: 35% (89 aa)

CYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNS-GGYINASRVKVPvaGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYW
... .||| .||.||.|||.  |||||  ...   .||||. .| .   . |.|||||||. .|..|.|||.||  .... |. .. ||| || .|||. 
teagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgv--egkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryW

PDCTspkKNTAEFGPFRVIAQFSNDSG-CYITSGLTLRHVpsGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRhansmnevEVGPPPIVHCSA
.   ... |||.|.|  .  .     ..   |....   .|.|.|  ..|..||..|.|  ..  |...|..... ..   | .|||||||||||... .
peeg---eeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe--------sedaPlvvhCsa

GVGRTGVLLLVDIMISSLEHN---EEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQS
|.. . |...   ||... ...  ||.||  .|||  ||..||||...            
GvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase Spur_PTPN14.AA Subfamily.R_Anemone_1.PD 1043-1312 32 7.3e-60 193.9 In-house 4-257 (258) Show / Hide
Range on Protein: 1043-1312
Range on HMM: 4-257/258
Sequence Identity: 32% (87 aa)

TEYEQITKKREgAVCYTSKLPENVSRNRFKDVLPYEDCRVELSS-SHHNSGGYINASRVKVPVAGelLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLT
.|........|     ... .|| ..||..|..... .|| |.. |..... ||||| ...        .||.|.|.|.||.|.|||||.  ..|| |||
aefqrlkeike-eekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt--rafiatqapleetvedFWrmvwqekigviVmLt

KLKEDGKEKCFKYWPDctspkkNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVcrhaNSMNE
 |.|  |.|| .||||      .|...| .||  . ... . ||.  |.| .. . |.|.| ....||..| |.     |..... |.     .  ..  
nliegekkkchqYwPd------stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks----slaga

VevgpPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSL
   | .|||||||||||. | .| |.  . ... ..| ...  .|..|  ||||  ||.|...|... |  
r----pvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase Spur_PTPN14.AA Subfamily.N5_RR.PD 1061-1311 33 1.9e-59 192.3 In-house 19-263 (265) Show / Hide
Range on Protein: 1061-1311
Range on HMM: 19-263/265
Sequence Identity: 33% (84 aa)

KLPENVSRNRFKDVLPYEDCRVELSS--SHHNSGGYINASRVKVPvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWPDC
... . ..||.|..|| |  || |.|  |...   ||||  .| .  .|   |.|.|||. ||..|.|||...  .||| |||||||..|| .|.|| ..
evfgsqtknryktilPnensrvllesessededssyinanyikGy-deeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPda

TSPkKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSgEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFqsvcRHANSMNEVEVGPPpIVHCSAGVGR
  . . ..| . .  .  ..   |    |.|... .  .|.| |  | |||..  |||.. .|....|     ..... .. ...|  .||||||.||||
edy-eiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvlev----eesreeenaklaPv-vvhcsaGiGr

TGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQS
. . ..| .  |.... ... |..  ||..|  ||||  || ....||..   
tGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly

Phosphatase Spur_PTPN14.AA Subfamily.R_Ecdysozoa.PD 1043-1310 30 1.3e-56 182.9 In-house 4-266 (269) Show / Hide
Range on Protein: 1043-1310
Range on HMM: 4-266/269
Sequence Identity: 30% (81 aa)

TEYEQITKK-REGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSS-HHNSGGYINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAML
.|||.. ..      . .|.  ||  .||..|. .... || |.    ...  ||||| .|     |  ..||||.|.|.|..|.|||..|   ..| ||
eeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikg--ykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TKLKEDGKEkCFKYWP-DctspkkNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVP---SGEQRTVWHLQYNDWP-NQGCPDDVHGFLSFLEEFQSVCRH
..|.|  .. | |||| .      .. ..|   |    ..  . ||   |.. ..      ..| |.|. |. ..  |.  .| | ..|. ... .. . 
snlteknrk-cakyWpie------devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelykl

ANSMnevEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
.       | .|||||||||.|... .|...  |. .....| ...||.|| |.|| . ||.|.|.||..     
nkls---gsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase Spur_PTPN14.AA Subfamily.RG.PD 1043-1310 31 1.7e-55 179.5 In-house 4-261 (264) Show / Hide
Range on Protein: 1043-1310
Range on HMM: 4-261/264
Sequence Identity: 31% (86 aa)

TEYEQITK-KREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNSG-GYINASRVKVPVagELLHYIAAQGPMENTVQDWWRMVWESGTQVIAML
..|.|.| | .   . .|| .||  .||  .....|  ||.||.   . |  ||||| ..        .||..|||...|..|.|||.||.|.| |||.|
eqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyr--rskeyivtqgplketiedFWrmiWehnaqiivml

TKLKEDGKEKCFKYWPDctspKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGE--QRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFqsvcrhaNS
.| |......|||.    |... |.. ..|     .   .|..  ..|..    .  .|.| ...| .||..| |.    .|.| .         . .|.
tdldekgrrdedvyWPk----kdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke-------ea

MNEVEVGPpPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
 |.||  .||.||||||.|... .| ..  ||..| .|. ...  .|..|  .|.|  ||.|.|.||..   
ankeeaGP-ivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle

Phosphatase Spur_PTPN14.AA Subfamily.RA.PD 1045-1310 32 7.3e-55 177.3 In-house 6-263 (266) Show / Hide
Range on Protein: 1045-1310
Range on HMM: 6-263/266
Sequence Identity: 32% (89 aa)

YEQITKKREG-AVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSH-HNSGGYINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTK
....|. .   . . |....||  .||. ..|||.  || ||  . ...  ||||| ..     |  ..||||||.|.||.|.|||.||  .. | |||.
fkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidG--yrekdkfiaaqGpkeetvedfwrmiweqksativmlte

LKEDGKEKCFKYWPDctspkKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGE----QRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSvcrhans
||| ..||| .||||     . .  .|  ||  . .. .  |    . ....|       .| |  . .. ||. | | .  ||..|.. ..       .
lkerkeekcaqywpd-----eGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkk-------

MNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
.... . | .||||||||||| .. .| ..  .. .. ... ...  ||.||  ||||  ||.|.||.| . 
lqqqsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase Spur_PTPN14.AA Subfamily.RK.PD 1043-1311 27 4.8e-54 174.5 In-house 7-265 (267) Show / Hide
Range on Protein: 1043-1311
Range on HMM: 7-265/267
Sequence Identity: 27% (74 aa)

TEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHNSGGYINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTK
....| . . . | ..|...| ..||..|.|.|. ..| | | . .|  ||||. .         ..|..|||...||.|.||.|.. ..| |||.| .|
etlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalids--ykrpaafivtqgPlqetvkdfWrlvydencasivmlte

L-KEDGKEKCFKYWPDCTSpkkntAEFGPFRVIAQFSNDSGCYITSGLTLRH--VPSGEQRTVWHLQYNDWPNQ-GCPDDVHGFLSFLEEFQSVCRHans
 |. || ||||. |.      ..|...|    ..    ...  .....   .  |.|.| ..|.  ||.  . |.  ...|... . ...  .       
ldvevgrvkClkyWPedte-----vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee---

mneVEVGpPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQS
| | . .|||.|| ||.|. . .||..  .|... ... ...  ||.... ||.|  ||.||| . ..     
---eeeG-rivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase Spur_PTPN14.AA Subfamily.N1.PD 1055-1311 33 2.8e-53 172.2 In-house 18-266 (268) Show / Hide
Range on Protein: 1055-1311
Range on HMM: 18-266/268
Sequence Identity: 33% (85 aa)

AVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHnsgGYINASRVKVPVAGEllHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKY
. ..||||| ..||..|| ||. .|..| ...     ||||| |... |.   .|| .|||. .|.. .|.||||  .. . || |. |.. ||..||| 
letreaklpenrglnryrdvspydhsrikleradv---dyinaslveleeakr--rYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

WPDCTSPKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEfqsvCRHANSMNEvEVGpPPIVHCSA
 .. .. . |   ..|     ...  .... | |. . . | |.. | .|  ||. | |.    ||.|| .    .|.. |... .|| |...|||||.|
wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfk----vresgsLss-dvg-pavihCsa

GVGRTGVLLLVDIMISSLEHNEE---INIPKMMGILRQQRMLMVQTVGQYTFVYKALIQS
|.| | ||| ..  .|....   ..| | .  ||..|. ..||  |  | | |...    
gigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg

Phosphatase Spur_PTPN14.AA Subfamily.RC.PD 1043-1310 30 2.9e-52 168.8 In-house 4-285 (288) Show / Hide
Range on Protein: 1043-1310
Range on HMM: 4-285/288
Sequence Identity: 30% (87 aa)

TEYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVEL-----------------SSSH---HNSGGYINASRVKVPVAGEllHYIAAQGPMENTV
.|.... . |       .. .|| |.||. |||||.  ||||                 | ..   ...  ||||| ..     |   |||||||...||
aefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpe--kyiaaqGplketv

QDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWpdctspKKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGF
.|.|||..|  ..|| |||.|||  .||| .||      .. .  .|   |  .  . |  ||   | |..    . |.| ..|| .|.... |.. . .
ddfwrmiferkvkvivmltelkeGdrekcaeyw------eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkel

LSFLEEFQSVCRHANS--MNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
|....  .    . .|   ..     | .|||..|..|||. . .. .. ||| .| ... ...  ||..| |||..  || ..|..|..
lkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve

Phosphatase Spur_PTPN14.AA Subfamily.N23.PD 1078-1310 37 4.9e-52 168.2 In-house 115-347 (350) Show / Hide
Range on Protein: 1078-1310
Range on HMM: 115-347/350
Sequence Identity: 37% (87 aa)

EDCRVELS--SSHHNSGGYINASRVKVpVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWPDctsPKKNTAEFGPFRVIA
.  ||.|   .   .   ||||. .|  ..    ..||.|||...|. |.| ||||  ..|| |||| .| .| || .|||     . .|||..||  . 
dpnrvklqqstqpgqqddyinatylke-ltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPi---degetnlfgdlrvsl

QFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVC-RHANSMNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLE-
 ..|  .|   |.|.| .    |.| ||..  |.. | |.    .| ||.| ...  .. ..  | | | | |.||||||||||.. .|   |  |. .|
kslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelta

HNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
  ||||...  |||||  |||.. .. ..|.| ..  
gngiiniprvvrrlrqqRkymvqkkvilkklyeavle

Phosphatase Spur_PTPN14.AA Subfamily.N20.PD 1059-1312 37 8e-48 154.4 In-house 20-256 (257) Show / Hide
Range on Protein: 1059-1312
Range on HMM: 20-256/257
Sequence Identity: 37% (91 aa)

TSKLPENVSRNRFKDVLPYEDCRVELSSSHHnsggYINASRVKVPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWPdc
. . | |  .||..|.|||.  || |  |.     ||||| ...  .||   |||.|||. .|..|.|.|| |  ..||||.|.  | |||..|||   |
sgnqpsnreknryrdilpydstrvplgkskd----yinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywp--

TSPkKNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLeefqsvcRHANSMnevEVGPPPIVHCSAGVGR
  |.  |.  |||. .  .    .|   . .    .|  ..| .||.  ||..| |     |. ..       |.|.  | .||||||.|||||.| ||.
isl-kkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyi-------ryarks---hltgpmvvhcsagigr

TGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSL
.. .. .|  .||  ..  .|.||  ||||  || |.|  ... |         
tgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl

Phosphatase Spur_PTPN14.AA Subfamily.RN.PD 1046-1311 33 6.3e-47 151.2 In-house 7-262 (264) Show / Hide
Range on Protein: 1046-1311
Range on HMM: 7-262/264
Sequence Identity: 33% (87 aa)

EQITK-KREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSS-SHHNSGGYINASRVKvPVAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKL
| ... . | ... ..| ..||..|| |.||||.. ||.|.. . ...  ||||| .          |||.|||. .|. |.|.||||.|.|| .||.|.
ealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasail-dhdprapayiatqgplsstiadfwqmvweqGvvvivnltrl

KEDGKEKCFKYWPDCTSPKKNTAEFgpfRVIAQFSnDSGCYITSGLTLRHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRHANSmneve
|.| ..| .||||  |   .  |    .....    .  |.   . |. . . | |||  . .  ||..|.|   . .| |.   |   .        | 
eeegvkqckrywpdeGsevyhiyev---hlvsehi-wcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrsc-----

vgpPPIVHCSAGVGRTGVLLLVDIMISSLEH-NEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQS
.||||.|.||||| .|.|.... | .   ||.|   .  ||.||  .|.|  |. |...|...      
---pivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee

Phosphatase Spur_PTPN14.AA Subfamily.N_Nematode_6.PD 1061-1310 26 1e-43 140.7 In-house 20-250 (253) Show / Hide
Range on Protein: 1061-1310
Range on HMM: 20-250/253
Sequence Identity: 26% (67 aa)

KLPENVSRNRFKDVLPYEDCRVELSSSHHNsggYINASRVKVPVAGEllHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWPDCTS
. ..  |||....  ..  |..|.  ..    || |..||.    .   .| .|.|.|.|....|.|.  ||.. | || .| |.||||. .| .|    
aflkfkdrnrytniqCcdagrlkladdedf---yihanlvkistkpr--rlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvG

pkkNTAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSGEQ-RTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRhansmnevevgpPPIVHCSAGVGRT
  ..  .. .  . . ....   |..  ..| | .|..   | |.....||. | ||..   |.|. ...  .            | .||||||||||| 
---darkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk------------PivvhCsaGvGrt

GVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
| |. |.. .| . . .......  ||..|.  |||. || .... ...  
Gtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvle

Phosphatase Spur_PTPN14.AA Subfamily.N_Nematode_1.PD 1044-1310 28 2.2e-41 133.0 In-house 5-262 (265) Show / Hide
Range on Protein: 1044-1310
Range on HMM: 5-262/265
Sequence Identity: 28% (77 aa)

EYEQITKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSSHHnSGGYINASRVKVPVAGelLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKL
|.... |  .     . |  .. ..||.|||   .. || |...   .  || |  | .|.     ..| ||.|...|..|.| ||     . | || ||
efralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeepl-psdyihanyvgtptnp--krficaqaPldktiadfwymvlqekveaivmlckl

KEDGKEKCFKYWPDCTSPKKNTAEFGPFRVI-----AQFSNDSGCYITS-GLTLrHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLsfleefqsvcrhaN
 | || || .|.|  . .|..  | |   ..     ... ...   |.   |.. ... ...|.| |.|..|||..| |    . |             .
iekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlev-egaGektrkvthyqWtdWPdrGvPpadlaal-------------e

SMNEVEVGP-PPIVHCSAGVGRTGVLLLVDIMISSLEHNEEIN-IPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
 ...|..   | .||||||.|||| .. .. ..  | ....|. ..|..  .|.||   .||  || ||.. |..
lleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln

Phosphatase Spur_PTPN14.AA Subfamily.N_Nematode_4.PD 1049-1310 27 1.3e-39 127.3 In-house 10-261 (264) Show / Hide
Range on Protein: 1049-1310
Range on HMM: 10-261/264
Sequence Identity: 27% (75 aa)

TKKREGAVCYTSKLPENVSRNRFKDVLPYEDCRVELSSsHHNSGGYINASRVKVPvagELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGK
|... . . .|   .|  .||..|.|  .. || |   .. .  || || ...|   .  .||..|||...|..|.| ||..  ..|. || .| |.| |
vkgkappnvtasaseknsdknryadilcidetrvvlkn-rdpdndyihaswmrmP---dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegv

EKCFKYWPDCTspkKNTAEFGPFRVI--AQFSNDSGCYITSGLTLRHVP-----SGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLeefQSVCRhaNSMNE
|| .|.|. .   ... .|| .|.    .  .     |   |..  .      . |.  | |.|.. |..|  | |    . ..   . |    .. .. 
ekcaryypeks---ekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapvikly---kavkk--kkkek

vevgpPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
    |..||||||||||  |. .|.    .  | ||.. ...  ||. |.  ||.  |. |..  ||. 
-----PivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlie

Phosphatase Spur_PTPN14.AA PTPc_motif 1201-1310 30 3.8e-36 127.34 SMART 1-92 (92) Show / Hide
Range on Protein: 1201-1310
Range on HMM: 1-92/92
Sequence Identity: 30% (35 aa)

TVWHLQYNDWPNQ-----GCPDDVHGFLSFLEEFQSVCRHANSMNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMV
||.|..|..||..     |.|.  ...|.|......               |..||||||.||||.. ..|.|...      ..| ...  .|.||. ||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMV

QTVGQYTFVYKALIQ
||  || |.|.....
QTEEQYIFCYRCILE

Phosphatase Spur_PTPN14.AA Subfamily.N_Nematode_5.PD 1057-1309 24 1.9e-35 113.5 In-house 17-254 (258) Show / Hide
Range on Protein: 1057-1309
Range on HMM: 17-254/258
Sequence Identity: 24% (62 aa)

CYTSKLPENVSRNRFKDVLPYEDCRVelsSSHHNSGGYINASRVKVPVAGEllHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKlKEDGKEKCFKYWP
. ...  .|...|| |||  ... ||   . ...  .||||| .|.. . .  ..| .| |  .|..| |||| .   . ..|.. .|. ||.  ...|.
etckafeknlkknrskdvkilDetrV---kltdeddsYinaskiklddlek--kliltQlPlpdteedFWrmvyqekitsvvllve-deelketavsffp

DCTSPKKNtaeFGPFRVI-AQFSNDSGCYitSGLTLRHVPS--GEQRTVWHLQYNDWPNQGCPDDVHGFLSflEEFQSVCRHANSMNevevgPPPIVHCS
 |   .|   .| . .   .. ... ..  . .|.  .|   .|.  . . ... |...  ||.|   .    . ..| .. .. |     .| .|....
letgdyln---lgkmfinnrkvevkedek--keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgkn-----apvvvvsd

AGVGRTGVLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALI
|.||.| .||....| .|....|.|| ...  .|.||. .|...||..||.|..  
lGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase Spur_PTPN14.AA Subfamily.R_Nematode_2.PD 1065-1310 29 1.9e-35 113.5 In-house 29-258 (261) Show / Hide
Range on Protein: 1065-1310
Range on HMM: 29-258/261
Sequence Identity: 29% (69 aa)

NVSRNRFKDVLPYEDCRVELSSSHHNSGgyINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWPDCtspKKN
.  ..|..||   .. .||  .  . .   | |  |    ||.  ..||.|||.|||..|.| ||     . | ||..  ||||| .|.|     .... 
pkdkhRypdvPCkpetavevivdgkrvp--ihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfple---tsq

TAEFGPFRVIAQFSNDSGCYITSGLTLRHVPSG---EQRTVWHLQYNDWPNQGCPDDVhgflsfLEEFqsvcrhaNSMNEVEVGPPPI-VHCSAGVGRTG
..| |..  .  .      ..  ||. . |    . ||| |.||..||..| |..| |       . .. |     || ||||||.|||. .. .. . .
kldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPksh------aelf-------eLlelvkksekPivvhCsaGiGRtm

VLLLVDIMISSLEHNEEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQ
 .|....|.. ...  ||..|.  .||  |. .....             
afigteylareveadptieltealkelrehRwkgiqtesqlywltlgaly

Phosphatase Spur_PTPN14.AA Subfamily.R_Nematode_3.PD 1059-1309 20 2.5e-30 96.9 In-house 21-263 (267) Show / Hide
Range on Protein: 1059-1309
Range on HMM: 21-263/267
Sequence Identity: 20% (55 aa)

TsklpENVSRNRFKDVLPYEDCRVELSS-SHHNSGGYINASRVKVPvagELLHYIAAQGPM--------ENTVQDWWRMVWESGTQVIAMLTKLKE---D
.    ..|| .| ..|. .|. || |     . . ..|.|..|..|   . |. | .|.|.        ..|.. .| |. .......|| . .|   ..
s----kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecp---nglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedge

GKEKCFKYWPDctsPKKNTAEFGPFRV--IAQFSNDSGCYITSGLTLrHVPSGEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEefqsVCRHANSmnEVev
.||| .|.|.    ..   .|. . |  .   .. |    .  |.. ..  ... || ||.|..|.... |.. . .|. ..    .... ..   |   
eeekcseYype---kvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelik----fvekskt--pv--

gpppIVHCSAGVGRTGVLLLVDIMISSLEHNE-EINIPKMMGILRQQRMLMVQTVGQYTFVYKALI
   .||||.|..|...|  ... .  . ... .... ...  ||.||   .||  ...||   .. 
----vVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgil

Phosphatase Spur_PTPN14.AA Subfamily.N_Nematode_eak.PD 1063-1312 25 1.4e-25 81.3 In-house 24-280 (281) Show / Hide
Range on Protein: 1063-1312
Range on HMM: 24-280/281
Sequence Identity: 25% (66 aa)

PENVSRNRFKDVLPYEDCRVELSSSHHNSGGYINASRVKVPVAGEllHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEKCFKYWPDCTspk
|.| |||  ...|..   |.|.||  |  |||||| .. .  |.  .|| .  . |. |  .|.|| |  .  | .| .| . ||  ||.|| |    . 
leavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGr--kyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt---

kNTAEFGPFRVIA-QFSNDSGCYITSGLTLRHvpSGEQRTVWHLQYNDWPNQGCPDdVHGFLSFLEEFQSVCR-----H-A----NSMNEVEVGPP---P
 ..| . |   ...   . . |  | ||     |   | | ..  | .   |  ..||.. . .. |         .      ..     ||   ||. .
-evlkyGildverkeyavkrniletrllilrk--GnethrvlhykvfGwtettlpk-yedflalrkvmkevGvlllivmksallrstlkkyihtppsfap

IVHCSAGVGRTGVLLLVDIMISSLEHN--EEINIPKMMGILRQQRMLMVQTVGQYTFVYKALIQSL
. |  |.||....|..|  .. .  .   . ......|.  | .  |..|.|..... |       
iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl

Phosphatase Spur_PTPN14.AA Subfamily.N_Nematode_egg.PD 1059-1309 28 2.2e-25 80.7 In-house 20-253 (257) Show / Hide
Range on Protein: 1059-1309
Range on HMM: 20-253/257
Sequence Identity: 28% (73 aa)

TSKLPENVSRNRFKDVLPYEDCRVELSSSH-HNSGGYINASRVKVpvAGELLHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDgkEKCFKYWPD
|.   ..  . | | |   | .||.|   .   .. .| | |||      | ..| || |. |||.|.||||..   | ||||  ||   |.|  ||| .
taasdnylekarskrvhckessrvklelrrGqylddfihanrvkG--kpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpk

CTSPKKNTAeFGPFRVIAqFSNDSGCYITS---GLTLrHVPSGEQRTVWHLQYnDWPNQGcpdDVHGFLSFLeefqsvcRHANSMNEvevgpPPIVHCSA
 |    |   | .|. . .  ||          | |   .  |.. . | |. |. . .||.  |  |       |..  . .     | .|..  || .
aeseslvtv-pGslrien-lkvdskadplfrvtklkl-vGgddeelflehwqg-dvnyls---dvysplrvl-------rklrnlsk-----pvvvqdil

GVGRTGVLLLVDIMISSLEHN--EEINIPKMMGILRQQRMLMVQTVGQYTFVYKALI
...|. ..| . ||         . . . .||..|| |..| .| |||. ..     
GvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl

Phosphatase Spur_PTPN14.AA Subfamily.N_Fungi_PTP1.PD 1064-1158 33 2.8e-24 76.8 In-house 44-151 (343) Show / Hide
Range on Protein: 1064-1158
Range on HMM: 44-151/343
Sequence Identity: 33% (35 aa)

ENVSRNRFKDVLPYEDCRVELSS--------SH-HNSGGYINASRVKVPVAGEL----LHYIAAQGPMENTVQDWWRMVWESGTQVIAMLTKLKEDGKEK
|  ..||.|..||||  ||.|           | ...  ||||. .|... .       .|||.|.|. .||.|..... .. .|| .||.. | . |||
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek

CFKYWPDC
 .||..  
cyrYWqeg

Phosphatase Spur_PTPN14.AA Subfamily.N_Fungi_PTP1.PD 1197-1309 31 7.3e-18 55.8 In-house 210-339 (343) Show / Hide
Range on Protein: 1197-1309
Range on HMM: 210-339/343
Sequence Identity: 31% (38 aa)

GEQRTVWHLQYNDWPNQGCPDDVHGFLSFLEEFQSVCRH--ANSMNEVEVGPPPIVHCSAGVGRTGVLLLVDIMISS-------LEHNEEIN--------
.|  .|..||.. |.. .   . . .|. ||  . .     |.|  . . ..| .|||||||||||.|. .| ..|.. ....        |  .. .||
sepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl

IPKMMGILRQQRMLMVQTVGQYTFVYKALI
.||. |||.. |. |.|.||          
isiivnelrkqrismvqnldqfifiYeall

Phosphatase Spur_PTPN14.AA Subfamily.PTPDC1.PD 1250-1304 30 7.8e-06 16.6 In-house 171-220 (229) Show / Hide
Range on Protein: 1250-1304
Range on HMM: 171-220/229
Sequence Identity: 30% (17 aa)

VHCSAGVGRTGVLLLVdIMISSlehnEEINIPKMMGILRQQRMLMVQTVGQYTFV
||| || ||||||.   ... .    ....  . . ..|..|   .|| .|  .|
vHCHAGlGRtGvliac-ylvya----krltaeeaiklvrskrpksiqtreqvelv

Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPN14.AA Protein None 1318 None Fasta, JSON
Spur_PTPN14.NA RNA None 3954 None Fasta, JSON
Spur_PTPN14.AA.PD_1040-1313 Protein Phosphatase Domain None 274 None Fasta, JSON