• Phosphatome.Net

Gene Spur_PTPN3

Spur_PTPN3
Species: S.purpuratus
Alias: Spur_hmm68009, Spur_PTPN3, hmm123527
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N3
Protein domain

Protein domains of Spur_PTPN3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FERM_C Spur_PTPN3.AA FERM_C 9-99 43 3e-40 144.84 Pfam 1-99 (99) Show / Hide 
Range on Protein: 9-99
Range on HMM: 1-99/99
Sequence Identity: 43% (43 aa)

DTLGSE-IAIGVVSAGLSIF--QNGVRI---NQFSWAKIVKISFKRKQFFIQQR--REIGETRDMVIGFNMTSYRACKNLWKSCVEHHTFFRMVDPQPP
|  | . . .|| ..|. ..  |.. .|   | |.|..|.|||||||.|||..|  ...|| .. ...|.| .|||||.|||.|||||.|||   |...
DKKGTDTWWLGVCAKGINVYQVQDNNKITPMNTFPWPEIRKISFKRKKFFIKLRDDPDEGEKYEHTHTFYMPNYRACKYLWKCCVEHHQFFRLRRPPDT
FA Spur_PTPN3.AA FA 103-149 41 3.4e-10 39.08 Pfam 1-48 (48) Show / Hide 
Range on Protein: 103-149
Range on HMM: 1-48/48
Sequence Identity: 41% (20 aa)

RTFF-QLGSKFRYSGRTESQTMEDTKKRLAEKEISRSSPNKRAFRRTV
. ||  .||||||||||. ||.|  ...  ..     || ||  .|. 
KRFFCSWGSKFRYSGRTQYQTIEYSREHQRKPPQFHRSPSKRYPSRRS
PDZ Spur_PTPN3.AA PDZ 251-336 32 2.3e-20 72.32 Pfam 1-86 (86) Show / Hide 
Range on Protein: 251-336
Range on HMM: 1-86/86
Sequence Identity: 32% (29 aa)

TIRMLPD-DRGRFGFNVKGGADQG--APIIVSRVAPNTPADLCIPRLNEGDQILQINGKDASTFTNEQLVSTIRALGEARTKDLVLTVR
.... ..  ||..||..||| ||.   .|..|.| |. .|. . .|..|||||..|||.| . .| .. |  |.  ..     . ||..
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKG---GEVHLTIQ
Phosphatase Spur_PTPN3.AA PTPc 385-647 32 5.4e-113 382.61 SMART 1-308 (308) Show / Hide 
Range on Protein: 385-647
Range on HMM: 1-308/308
Sequence Identity: 32% (104 aa)

MAIAQFDQLYRKKPGM---------TMGACRLAENV--AKNRYR-DIAPYDATRVILREA-------DTGDYINANTINMDIPGFDLVNKYVAAQGPLPN
.  ..|. |.| .|..         ..  ... ||.   ||||. || .|| |||.|            .|||||| |...    .  ..| ..|||||.
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY----WRPKRYICTQGPLPH

TVNDFWYMVWEQRSTLIVMLTTNVER--------GRVKCHKYWPDLDDRLKFGPDLEVRCTRCDETP-SFAYRDFIICNTAT--------KEERIVLQMQ
|..||| |||.|... ||||.. .|.        ||.|||.||||    ...| ...| |.... .| ..  |.| ..|| .        .|.|.| . .
TIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYG-HITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYH

YVAWPDHGVPDDSSDFLDFVLRVRQCRVGM-------------------DVPTIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLI
| .|||||||.....||||. .||...                      . |..||||||.||||...........||.   | ...||.. |.|||...
YTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMV

QTAAQYKFVCEAIIRVYM
||..||.|....|.....
QTEEQYIFCYRCILEYIK
PDZ Spur_PTPN3.AA PDZ 260-339 29 6.6e-16 60.09 SMART 1-80 (80) Show / Hide 
Range on Protein: 260-339
Range on HMM: 1-80/80
Sequence Identity: 29% (25 aa)

GRFGFNVKGGADQGAPIIVSRVAPNTPADLCI----PRLNEGDQILQING-KDASTFTNEQLVSTIRALGEAR-TKDLVLTVRPNE
| .||...|      .|..|.| |..||. .     ..| .||.||..|| .. ...| || |  ... |. .  . ..|||....
GGLGFSIVG------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG
Phosphatase Spur_PTPN3.AA Subfamily.N3.PD 386-647 66 1.4e-139 454.8 In-house 2-261 (261) Show / Hide 
Range on Protein: 386-647
Range on HMM: 2-261/261
Sequence Identity: 66% (174 aa)

AIAQFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILREADTgDYINANTINMDIPGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVML
.|||..|||||||... |.|..||.||||||||.|||||||.|.|..| ||||||..||.||...|||.|.|.||||..|..|||.|||||.||||||||
vlaqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivml

TTNVERGRVKCHKYWPDLDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDVPTIVH
|.|||||||||.|||. .|.|.|| ...|||...||| |. .|........||||| .||.||.|||||||||||.|||.|| |||..| |.. |..|||
ttlverGrvkChqyWPetedelefg-efsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvh

CSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRVYM
|||||||||||..|||..||||.||||||||||| |||| ||.||..|||||||||...|. 
CsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailkaye
Phosphatase Spur_PTPN3.AA Y_phosphatase 410-644 39 2.4e-108 371.06 Pfam 1-243 (243) Show / Hide 
Range on Protein: 410-644
Range on HMM: 1-243/243
Sequence Identity: 39% (97 aa)

NVAKNRYRDIAPYDATRVILR---EADTGDYINANTINMDIPGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGR-VK-CHKYWPD--
|  ||||.|| .|| |||.|    . . .|||||| |..    .   ..| ..|||.|.|..||| |||.|..| ||||....|.|| .| ||.||||  
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG---PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNK

LDDRLKFGPDLEVRCTRCDETPSFAYRDFIICNTAT--KEERIVLQMQYVAWPDHGVPDD-SSDFLDFVLRVRQCRV-GMDV--PTIVHCSAGIGRTGVL
 .. ...| |..| |......| .  |.| ..|  .  .|.|.| . .| .|||||||.. . ..|||. .||...  ...   |..||||||.||||..
EGQPMTYG-DFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTF

ITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
..........|... |  ..||.. | |||...||..||.|....|. 
CAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Spur_PTPN3.AA Subfamily.N13.PD 389-645 42 3e-79 257.4 In-house 5-257 (259) Show / Hide 
Range on Protein: 389-645
Range on HMM: 5-257/259
Sequence Identity: 42% (110 aa)

QFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILREADTgdYINANTINMDIpGFDlVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTN
.|..|   ||  |    . .|| .|||||.. |||.|||.| .  .  ||||. |.. . | |   .|.|.|||||.||.||| |||||....|.|.|..
efkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg--yinaslikvpv-ged-eyeyiacqGPlPetvkdfwqmvweqkaeviamvtle

VERGRVKCHKYWPDLD-DRLKFGPDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVgMDVPTIVHCS
.|.|.||||.|||.   ..||    |||.  .  .  .|. |.. . .....| | | ....|.|||||||  . ... || .||..     | .|||||
kekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhcs

AGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRV
||||.|||||..... ||| ....   .|||. |.||  ..||  || || .||. | 
aGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev
Phosphatase Spur_PTPN3.AA Subfamily.RB.PD 390-645 41 4.6e-77 250.1 In-house 6-259 (261) Show / Hide 
Range on Protein: 390-645
Range on HMM: 6-259/261
Sequence Identity: 41% (105 aa)

FDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVIL---READTGDYINANTinmdIPGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLT
...| . .  ... | ..|.| ||||.. |.|||..|| |   .. .. ||||||     |||.   ..|.|.|||||.||.||| ||||..|.||||| 
yeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinany----ipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

TNVERGRVKCHKYWPDLDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNtaTKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGM--DVPTIV
 ||.|..||..|||. ..   .| |..|  .  .|. ... |.| |..   ||.| | |.....|||||||....  |||| .||.. |..||||||.||
qlvEkgkekceeYWPadeepvlyG-dikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivv

HCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRV
||. |.... .  ||.|. |  . .|   | .| .|.|| .|| |. |.....        
HCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl
Phosphatase Spur_PTPN3.AA Subfamily.N_Choan_1.PD 388-645 37 2e-76 248.1 In-house 4-260 (262) Show / Hide 
Range on Protein: 388-645
Range on HMM: 4-260/262
Sequence Identity: 37% (98 aa)

AQFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVIL---READTGDYINANTInmdiPGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVM
....|.    . |  | .  ||| ||||..|  |||||| .    |. . |||||| .    ||..  ..|.|.|||.|.....|||||||. ..|||.|
eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfv----pgykgekeyiatqgPvPaslvsfWqmvweqkvsaivm

LTTNVERGRVKCHKYWPDLDDRLKFGpDLEVRCTRCDETPSFAYRDFIIcNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRV-GMDVPTI
 ..| |..|||.|||| . .||.| |. |. ..  |..... | | . .. . |.| | |..|.||||||||......|.|   |....    ..| ..|
vtreieagklkChryWPdenselklg-dvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplv

VHCSAGIGRTGVLITMETAMCLIEANEPV-YPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRV
||||.||||. |......  .|.....  . ..|.  | .| ...|| .||.||  |...   
ihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
Phosphatase Spur_PTPN3.AA Subfamily.R_Anemone_2.PD 389-643 38 4.5e-72 233.9 In-house 5-258 (262) Show / Hide 
Range on Protein: 389-643
Range on HMM: 5-258/262
Sequence Identity: 38% (101 aa)

QFDQLYRKKPG-MTMGACRLAENVAKNRYRDIAPYDATRVILREA---DTGDYINANTInmdiPGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVM
....| |..   .|. ..    | ||||| .| .|| ||| |..     . |||||| |    .|.   ..|.|.|.|||.|..||| ||||| |..|||
eyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyi----dGyrrkkayiatqaPlpetiedfWrmvWeqnsavivm

LTTNVERGRVKCHKYWPDLDDrLKFGpDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRV-GMDVPTI
||  .|||..|.|.|||. .   ..| .| |  .   |. ..  | | . .| ..|||.| | .| .|||.|||......||.| .|..        |..
ltqeeergkakvhryWPskgs-rsyg-klvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpiv

VHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAII
||||||.||||| |.... .  |.|.. |  ...|.. |.||....||  ||.|..... 
vhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvll
Phosphatase Spur_PTPN3.AA Subfamily.N6.PD 398-643 38 6.4e-70 226.9 In-house 28-291 (295) Show / Hide 
Range on Protein: 398-643
Range on HMM: 28-291/295
Sequence Identity: 38% (101 aa)

PGMTMGACRLAENVAKNRYRDIAPYDATRVILREA---DTG-DYINANTI--------NMDIPGFD-LVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVM
..    . .|| .||||..| |.| |||||..     .| |||||| |        . . .. .   ..|.|.||.|..||.||| |||..|..|||.| 
klysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivm

LTTNVERGRVKCHKYWPDLDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNT-ATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQC--RVGMDVP
.||||. || .||||  .. ..| ...|.... ..| ..  |.| ...  . ||.| . |... |||||||| |.. .|.|.  |..   ..    |..|
ttkevergknkCarYWPdeetkketG-vitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagp

TIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRT---ERDQRPMLIQTAAQYKFVCEAII
|||||||||| .| ... . .|| .   ...|| ..    | ||  |.||.||||||  |.    
ivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq
Phosphatase Spur_PTPN3.AA Subfamily.R_Sponge_2.PD 391-643 35 1.1e-69 226.1 In-house 6-258 (262) Show / Hide 
Range on Protein: 391-643
Range on HMM: 6-258/262
Sequence Identity: 35% (91 aa)

DQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILRE--ADTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTN
..  .|.  ... . .| |||.|||...| ||| .|| ||.    ..|||||. ..    |.   . |.|.||||..||.||| ||||.... |||||  
eksveketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvd----gykrrkayiatqgPlketveDfWRmvweykvstivmltnl

VERGRVKCHKYWPDL-DDRLKFGPDlEVRCTRCDETPSFAYRDFIICNTATKEERI-VLQMQYVAWPDHGVPDDSSDFLDFVLRV-RQCRVGMDVPTIVH
.|.|. ||.||||.  |.. ..|   .|  .   ... .. |.. .... ..|..  | | ..||||.|.||.|.. .|... || |. .   ... .|.
eengkekcakYWPekvdeeveygkf-kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvv

CSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAII
||.|.||||  |.... .  ..|.| .   ....| | .|..|.|.||||.|. .|. 
CsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdall
Phosphatase Spur_PTPN3.AA Subfamily.N12.PD 387-644 38 5.8e-68 220.1 In-house 9-267 (270) Show / Hide 
Range on Protein: 387-644
Range on HMM: 9-267/270
Sequence Identity: 38% (102 aa)

IAQFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILREA---DTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIV
. .  . |...  ..  | .  |||.||||.|| ||| .||.|..    .  |||||| |.    | .   .|.|||||||.|..||| |.||.. ...|
lkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfik----gvegkleyiaaqgPLpktlddfWrmiweknveivv

MLTTNVERGRVKCHKYWPDL-DDRLKFGpDLEVRCTRCDETP-SFAYRDFIIcnTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDVP
|.  .|| |. ||..|||.  ...|.|| ..|| ... . .   |  | . .  .| ||.|.| |..| ||||||||   .. |...  ||. .   |.|
maCrevelgkkkCeryWpeegeeelefg-efevtleeekavdddflirtLkv--eaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaP

TIVHCSAGIGRTGVLITMETAMCLIEANEP---VYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
 .||||||.||||..|... .  |..|.     .   |.| . | ||. |.||  ||..| .|.. 
lvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
Phosphatase Spur_PTPN3.AA Subfamily.N14.PD 388-644 37 1.8e-66 215.4 In-house 4-272 (275) Show / Hide 
Range on Protein: 388-644
Range on HMM: 4-272/275
Sequence Identity: 37% (102 aa)

AQFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILREA--DTGDYINANTINMDIPGFDlvNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVML
...... .|.   .. ...| ||. |||..|. ||. .|| |  .  .. .|||| .|.. . | .   .|..|||||..||.||| |||||.|||||| 
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggke--rsyivaqgPleltvqdfwqmvweqgvqlivml

TTNVERGRVKCHKYWPDL---DDRLKFGPdLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVG-----
. | |. |..||.|.|    ....||   .|     ....|.. . . .    .|||| |. .||. |||||||.| ..||.|..|.  |          
teeeedgkeksfkylPkleskkktvefgk-fkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsev

-----MDVPTIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
  .. | .||||||.|||||||. .  .  .| || .    .... | || .|.|| |||||| ...|.   
esvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlik
Phosphatase Spur_PTPN3.AA Subfamily.R_Anemone_1.PD 390-644 33 2.2e-64 208.8 In-house 6-255 (258) Show / Hide 
Range on Protein: 390-644
Range on HMM: 6-255/258
Sequence Identity: 33% (87 aa)

FDQLYrKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLT
|..|  ... ... ..| ||| .|||| || ..| .||.|..    ...|||||  ..    ..|  ....|.|.||..||.||||||..... |||||.
fqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylr----asdktrafiatqapleetvedFWrmvwqekigviVmLt

TNVERGRVKCHKYWPDldDRLKFGpDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDVPTIVHC
 .|    |||.||||     |.| .|.|. .. ..   .  | ... .. ..|||.| |.... |||.|||. . . |... .|.. .   . | .||||
nliegekkkchqYwPd--stekyg-elrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhC

SAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
||.||||. . ... .  . ... |   ..|.. | .|| ..||  || |. .|... 
saGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavle
Phosphatase Spur_PTPN3.AA Subfamily.RA.PD 401-644 36 8e-64 206.8 In-house 18-263 (266) Show / Hide 
Range on Protein: 401-644
Range on HMM: 18-263/266
Sequence Identity: 36% (89 aa)

TMGACRLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCH
.. .. . ||  |||. .| ||| .||||      .. |||||  |.    |.   .|..|||||. .||.||| |.|||.|. |||||   ||.. ||.
klrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfid----GyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekca

KYWPDlDDRLKFGpDLEVRCTRCDETPSFAYRDFIIC----NTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDV-PTIVHCSAGIGR
.|||| .  . .| .. |    . .. ... |||..     .|  |..|.| |. . .||. ||| ..   |... .|....  .| .||||||.|||| 
qywpd-eGlvtyG-eirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGr

TGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
.|.... .  ..|.. .   ..|.. | ||| ..||  ||.|. ...     
tGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle
Phosphatase Spur_PTPN3.AA Subfamily.N9.PD 389-643 37 2.9e-63 205.1 In-house 5-271 (275) Show / Hide 
Range on Protein: 389-643
Range on HMM: 5-271/275
Sequence Identity: 37% (102 aa)

QFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVML
.. .. ....  |. | .|  |. |||| |.  || ||| | .    .. |||||| ..    |.   . ..|.||||..||.||| |||||.||| |  
eyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvd----GykqkkafiatqGplkktvsdfwrmvweqevlvivmt

TTNVERGRVKCHKYWP-DLDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRV------G-
|||||.|| .||| . ... .|| ||.|.    ...  .  | . | |. |.|.| |   |...|||.|||......||.. .||. .       |    
trvvergrlkcgqywpleeessaefg-dlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgd

------MDVPTIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAII
    . | .||||||||||| .||.. ..  .|  . |   . |.. | ||   |||  ||.|   |..   
eskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavl
Phosphatase Spur_PTPN3.AA Subfamily.R_Ecdysozoa.PD 397-644 32 9.7e-63 203.0 In-house 14-266 (269) Show / Hide 
Range on Protein: 397-644
Range on HMM: 14-266/269
Sequence Identity: 32% (84 aa)

KPGMTMGACRLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGR
.   .  .    ||  ||||.|| ..| |||.|..    .. |||||. |.    |..  .|..|||.|. .|..||| |..||.||||||.   |  | 
eiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfik----gykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknr

VkCHKYWPDlDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNTA---TKEERIVLQMQYVAWP-DHGVPDDSSDFLDFVLRVR-----QCRVGMDVPTIV
 |.||||. .|  ..| |. |.. . .... .. |.. . ..     ...| |.| .| .|. |  ||..   |... .||     .  .|   | .|||
k-cakyWpi-edevqyg-dilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivv

HCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
||| ||.|......  .  ..|.. |  ...|.  | ||..|.|  .||.|.|..     
hCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad
Phosphatase Spur_PTPN3.AA Subfamily.RK.PD 404-644 33 1.1e-61 199.5 In-house 23-264 (267) Show / Hide 
Range on Protein: 404-644
Range on HMM: 23-264/267
Sequence Identity: 33% (83 aa)

ACRLAENVAKNRYRDIAPYDATRVILRE--ADTGDYINANTInmdiPGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTN-VERGRVKCHKYW
.. . .| .|||. || .|| ..|.|     |  |||||. |     ..   ......||||..||.||| .|...... |||||   ||.||||| |||
iakkdrnreknrsmdilaydrslvflisvdgdssdyinaali----dsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyW

PDlDDRLKFGpDLEVRCTRCDETPSFAYRDFIICN--TATKEERIVLQMQYVAWPDH-GVPDDSSDFLDFVLRVRQCRVG-MDVPTIVHCSAGIGRTGVL
|. | . ..| |..| . ...    .  | | ...   . .| |.| |.|...||.. .||.    .|... || . .    . ...|||.|| ||.|. 
Pe-dtevryg-dikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtf

ITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
|.... . .|| .. |    .|.| |.... ...|  ||||| ..|. 
iaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvile
Phosphatase Spur_PTPN3.AA Subfamily.N1.PD 404-644 36 3e-59 191.9 In-house 22-265 (268) Show / Hide 
Range on Protein: 404-644
Range on HMM: 22-265/268
Sequence Identity: 36% (91 aa)

ACRLAENVAKNRYRDIAPYDATRVILREADTgDYINANTINMDipgfDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPDL
. .| || ..|||||. ||| .|..|..||. |||||. ....     .  .|. .|||||.|.. || ||||| |  ..||   ||....||..|||  
eaklpenrglnryrdvspydhsrikleradv-dyinaslvele----eakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqe

DDR--LKFGP-DLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRV--GMDVPTIVHCSAGIGRTGVLIT
...  |..   .|.|.  . ...  |  | . . .  |.| | .|. .|  ||| |||.  . ||.|...||.  .     .|...||||||||.| |  
eeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlsl

METAMCLIEANEPVYPLDIVR---TERDQRPMLIQTAAQYKFVCEAIIR
..| . .||... .  .|| .     | .|  ||||. | .|   ||. 
vdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile
Phosphatase Spur_PTPN3.AA Subfamily.RG.PD 389-644 33 4.7e-59 191.2 In-house 5-261 (264) Show / Hide 
Range on Protein: 389-644
Range on HMM: 5-261/264
Sequence Identity: 33% (87 aa)

QFDQLYR-KKPGMTMGACRLAENVAKNRYRDIAPYDATRVILREA---DTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVM
||... . |.  ... . .  ||  |||. .| ... .|| |..    |  |||||. |.    |.   ..|...||||..|..||| |.||.....|||
qfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyid----GyrrskeyivtqgplketiedFWrmiWehnaqiivm

LTTNVERGRVKCHKYWPDLDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNTATKEERI--VLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDVPT
||  .|.|| ....|||. |. |... .|.|. .. ... ..  |||.. || ...|.   | | .|  |||.|.|. . ..| || ....     |..|
ltdldekgrrdedvyWPkkdeplele-alkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPi

IVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
|.||| ||.|..| ..| .  .|..| |  ...... | .||.|..|  ||.|. .|..   
vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle
Phosphatase Spur_PTPN3.AA Subfamily.N_Choan_2.PD 407-644 37 5.6e-59 190.7 In-house 18-263 (266) Show / Hide 
Range on Protein: 407-644
Range on HMM: 18-263/266
Sequence Identity: 37% (93 aa)

LAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINmdipGFDLV-NKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPD
| | . |||.|| |  ||||.| |    ..  ||||| ..    |||   .||.||.||||.|...|| |.||...| |||.|  .|.|| || .|||  
yarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvr----GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa

LDDRLKFGPDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSS------DFLDFVLRVRQCRVGMDV--PTIVHCSAGIGRTG
 ..     | ... . . |. .  |.   .  .. .|.| .   .|..||||||| ..       . |. .||. |  .|   |..||||||.||||.||
epkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtG

VLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIR
....|..|.| .. | .| |..  | .|. |.|.  ||... .|..    
tliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve
Phosphatase Spur_PTPN3.AA Subfamily.N5_RR.PD 406-643 38 9.1e-59 190.2 In-house 19-261 (265) Show / Hide 
Range on Protein: 406-643
Range on HMM: 19-261/265
Sequence Identity: 38% (93 aa)

RLAENVAKNRYRDIAPYDATRVILR----EADTGDYINANTINmdipGFDLVNK-YVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYW
... .  ||||..| | . .||.|.    |..  .||||| |     |.| ..| |||.|||||||..||| |........|||||   |.| ||..|.|
evfgsqtknryktilPnensrvllesessededssyinanyik----GydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyf

PDLDDR---LKFGpDLEVRCTRCDETPSFAYRDFIICNTATkEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDV---PTIVHCSAGIGRTG
|  |     ..| |.|.. .   |.  .  | ... ..    || |  . | .|||| .||| . .||.|| |.. |   .| .|||||||||||. |..
Pdaedyeiseryg-dveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtG

VLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAII
. |.  ..... |  | ||   | .|  ..||. ||... .|..     
cfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
Phosphatase Spur_PTPN3.AA Subfamily.N23.PD 423-644 30 2.6e-53 172.5 In-house 115-347 (350) Show / Hide 
Range on Protein: 423-644
Range on HMM: 115-347/350
Sequence Identity: 30% (72 aa)

DATRVILR----EADTGDYINANTINMDIPGfdlVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPDLDDRLKFGPDLEVRCT
| .|| |.       . |||||  .    |.     ...|.|||...|..||| |||||.| .|||||..||... ||..|||   .. .  .||.| . 
dpnrvklqqstqpgqqddyinatylkeltpm---sPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslk

RCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCR-----VGM----DVPTIVHCSAGIGRTGVLITMETAMCLIEAN
.  ... .  |.. .  . ..  | | .... .|...|||.  .|.|.|.  |...      . .    . | |.|||||.||||..  . .|.  ..|.
slrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltag

EPVYP-LDIVRTERDQRPMLIQTAAQYKFVCEAIIR
...   ...||. | ||   .|. ...|.. ||...
ngiiniprvvrrlrqqRkymvqkkvilkklyeavle
Phosphatase Spur_PTPN3.AA Subfamily.RN.PD 401-643 37 5.7e-52 167.8 In-house 18-260 (264) Show / Hide 
Range on Protein: 401-643
Range on HMM: 18-260/264
Sequence Identity: 37% (93 aa)

TMGACRLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINMDIPGfdlVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCH
|  ...  .|| |||.... ||| .|| |.|   |.. ||||| .|  . |       |.|.||||..|. ||| ||||| ...||.||.  ||  .|..
tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdpr---apayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqck

KYWPDLDDRLKFGPDLEVR--CTRCDEtpsFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRVGMDVPTIVHCSAGIGRTGV
||||    .    ....      ||.   .  | | . |  |.| | | |. ...||..|||  .  .|.|  .| ..  |   | .||||.| ||||| 
rywpdeGsevyhiyevhlvsehiwcdd---ylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGv

LITMEtaMCLIEANEPVYPLDIVRT---ERDQRPMLIQTAAQYKFVCEAII
| ..  . |   .  |  .||. |    ||||| |..| .|..|.  |.. 
yilid--lvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltava
Phosphatase Spur_PTPN3.AA Subfamily.N20.PD 407-645 38 4.6e-51 165.1 In-house 23-255 (257) Show / Hide 
Range on Protein: 407-645
Range on HMM: 23-255/257
Sequence Identity: 38% (92 aa)

LAENVAKNRYRDIAPYDATRVILREadTGDYINANTINMDIPGFDLVnkYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPD-LDD
|  ||||||| |||.||| | .  . |||||. | .   | . .  |.|.|||| .|..||| || |. | .| |.| ..| | .||..|||  |   |.
qpsnreknryrdilpydstrvplgk--skdyinasyirivncgeeyf--yiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkk

RLKFgPDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRvgMDVPTIVHCSAGIGRTGVLITMETAMCL
.   . |     .    |  | | . . .|   . | |.|.  ||||| |  .  |. ..   |...  .  | .||||||||||||.. ..  .| |  
plel-khfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh--ltgpmvvhcsagigrtgvflcvdvvfca

IEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRV
|  .  .|||   |.||  ..||  ||.|. . .. |   
ivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlev
Phosphatase Spur_PTPN3.AA Subfamily.N_Nematode_1.PD 389-643 30 4.3e-49 158.4 In-house 5-261 (265) Show / Hide 
Range on Protein: 389-643
Range on HMM: 5-261/265
Sequence Identity: 30% (82 aa)

QFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVIL-READTGDYINANTINMDIPGfdlvNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTT
.| .| . ..  .. | . |..  ||||.|.   | .||.| .|. . ||| || . . .      .... ||.|| .|..||||||  ..   ||||  
efralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnp----krficaqaPldktiadfwymvlqekveaivmlck

NVERGRVKCHKYWPDLD-DRLKFGPD---LEV----RCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRvgmd
 .|.|..||..|.|  . ..|.|  .   . |    ..   .|. ..     .  . | ...| | ..|.  |||.|||      |... .||. .    
liekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk----

VPTIVHCSAGIGRTGVLITMETAMCLIEANEPVYPL-DIVRTERDQRPMLIQTAAQYKFVCEAII
.|..||||||||||| ....|  .  . ... . .  ..|.  |.|| . ||| ||| ||   ..
gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvll
Phosphatase Spur_PTPN3.AA Subfamily.RC.PD 388-646 30 1.3e-48 156.9 In-house 4-287 (288) Show / Hide 
Range on Protein: 388-646
Range on HMM: 4-287/288
Sequence Identity: 30% (88 aa)

AQFDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVIL-------RE--AD----TGDYIN----ANTINMD-IPGFDLVNKYVAAQGPLPNTVND
|.| .| . .  .|.  .|  || .|||| |. |||  || |       .|   |    . | |.    .. ||   | ..   .||.||||||.||.||
aefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvdd

FWYMVWEQRSTLIVMLTTNVERGRVKCHKYWpdLDDRLKFGpDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVL
| |..|.. ..|||||   |  | || .||   . .  .| |.||     | ....  | . . |   |. | | |.|| .|.....|..   .|...  
fwrmiferkvkvivmltelkeGdrekcaeyw--eeGkrayG-dvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliq

RVR----------QCRVGMDVPTIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRVY
|.            .  .  | .|||..| .|||. |.... .  .||.| |   ..|.  | .||..... .||... .... .| 
vvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvety
Phosphatase Spur_PTPN3.AA Subfamily.N_Nematode_4.PD 405-643 32 2.6e-47 152.6 In-house 21-260 (264) Show / Hide 
Range on Protein: 405-643
Range on HMM: 21-260/264
Sequence Identity: 32% (77 aa)

CRLAENVAKNRYRDIAPYDATRVILREA-DTGDYINANTINMDipgfDlVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPDL
.|  ||||.||   |.|||.|..     ||| |. . |     |   .|...||||..|..|||.||.... . .||| ..| |  || .|.|. ...  
saseknsdknryadilcidetrvvlknrdpdndyihaswmrmP----d-kfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypek

DDR-LKFGpDLEVRCTRCDET--PSFAYRDFIICNTA-----TKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQcrVGMDVPTIVHCSAGIGRTGV
||| . ... . . |      ... . . ||      . |. .|  .|.  |.|.  | |....   |..     . | .||||||.|||  |. .. | 
sekvvkfG-kyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtat

LITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAII
  |  |  .  |||||  |  |   .|.  |. |.   .|        
lvGidyatirirenseievldivrelramrlkavqshlqflfllvvli
Phosphatase Spur_PTPN3.AA Subfamily.R_Nematode_2.PD 410-640 29 3.9e-39 125.7 In-house 29-254 (261) Show / Hide 
Range on Protein: 410-640
Range on HMM: 29-254/261
Sequence Identity: 29% (66 aa)

NVAKNRYRDIAPYDATRVILREADTGDYINANTINMdipgFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWP-DLDDRLK
.  |.|| |.   . |.|     ..   | || ..         ....|.|||| ||..||| ||  .    ||||. .||. .||..|.| .  ..|..
pkdkhRypdvPCkpetavevivdgkrvpihanwvpt----agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld

FGpDLEVRCTRCDET--PSFAYRDFIICNTAT-KEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCrvgmDVPTIVHCSAGIGRTGVLITMETAMCL
|  .... .  ..    .   | . . ..    . | |  .||  |||.|||.   .  . .  |... | .||||||||||. .|..|     .||.. 
lg-rfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkks----ekPivvhCsaGiGRtmafigteylare

IEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCE
.   . ..  |..|.. |||  |. ..        
veadptieltealkelrehRwkgiqtesqlywltl
Phosphatase Spur_PTPN3.AA Subfamily.N_Nematode_5.PD 407-643 24 2.1e-37 119.9 In-house 22-254 (258) Show / Hide 
Range on Protein: 407-643
Range on HMM: 22-254/258
Sequence Identity: 24% (58 aa)

LAENVAKNRYRDIAPYDATRVILREADtGDYINANTINMDIpgfdLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKChKYWPDLDDR
.|. |||. |.  .|.|||.| . |  .||||..|..|     | .|.. .| |||.|..|||.|| ... |..|.|... |. .. ...|.  .  .  
feknlkknrskdvkilDetrVkltded-dsYinaskikldd----lekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgd

LKFGPDLEVRCTRCDETPSF--AYRDFIICNTaTKEERIVLQMQYVAWPDHGVPDDSSDFLD-FVLRVRQCRVGMDVPTIVHCSAGIGRTGVLITMETAM
 .. ..... ..       |   .. .    |. ..   ..  |... |||.... .   . .|.  .| . |..|....|.||.| ......|.. ...
ylnlgkmfinnrkvevkedekkeytvevlpeg-csesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvai

CLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAII
.. .   .|... |.|||  .....|| .| .|..     
eqlnngkepnideilkkirsqRpgavesliqyasvyaavl
Phosphatase Spur_PTPN3.AA Subfamily.R_Nematode_3.PD 406-646 25 3.5e-37 119.4 In-house 19-266 (267) Show / Hide 
Range on Protein: 406-646
Range on HMM: 19-266/267
Sequence Identity: 25% (66 aa)

RLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINMDipGfdlVNKYVAAQGPL--------PNTVNDFWYMVWEQRSTLIVMLTTNVE---R
.| ..|...|. ... . .|||.| .     . |.|.|| ...   .    .| . .|.|.         .|.. || |. ..... .|||  .||   .
slskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecp--n---glklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedge

GRVKCHKYWPDL-DDRLKFGpDLEVRCTRCDETPS--FAYRDFIIcNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRvgmdVPTIVHCSA
.  || .|.|.  |  |||. ...|.|| ... .|  .  |.. . .   |.|  |  ..| .|.....|...  .|. .  |....     | .||||.
eeekcseYypekvdgelkfe-gvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsd

GIGRTGVLITMETAMCLIEANE-PVYPLDIVRTERDQRPMLIQTAAQYKFVCEAIIRVY
||.|...|  .| .. ||  ..  .  |...   | ||.. |||. .. |||...    
GisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkll
Phosphatase Spur_PTPN3.AA Subfamily.N_Nematode_6.PD 407-642 28 4.7e-37 119.0 In-house 21-248 (253) Show / Hide 
Range on Protein: 407-642
Range on HMM: 21-248/253
Sequence Identity: 28% (68 aa)

LAENVAKNRYRDIAPYDATRVILREaDTGDYINANTINMDIPgfdlVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPD-LDD
. ..  .|||..|  .||.|. | . |   || || ...        .... .|.|| .|...|| |.  . .. ||||   ||.|. |. .| .| . |
flkfkdrnrytniqCcdagrlklad-dedfyihanlvkistk----prrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGd

RLKFGPDLEVRCTRCDETPSFAYRDFIICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVLRVRQCRvgmdVPTIVHCSAGIGRTGVLITMETAMCL
  |..   .|     ..      |  .    |..|| ||  ... .||||||||.    | ..  |....     | .||||||.|||| |. .....  
arkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhCsaGvGrtGtlaliliilea

IEANEPVYPLDIVRTERDQRPMLIQTAAQYKFVCEAI
.   .     |..   |..|   .||  || ..   .
lrlpdfqgvkdllvklreerfravqtevqylyalrcv
Phosphatase Spur_PTPN3.AA PTPc_motif 543-644 34 1.4e-36 128.79 SMART 1-92 (92) Show / Hide 
Range on Protein: 543-644
Range on HMM: 1-92/92
Sequence Identity: 34% (37 aa)

IVLQMQYVAWPDH-----GVPDDSSDFLDFVLRVRQCRVGMDVPTIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLDIVRTERDQRPMLIQTAAQYKF
.| ...| .||||     |||.  ...|.|. .||.       |..||||||.||||........|..      |  ...|.  |.|||...|| .||.|
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

VCEAIIR
....|. 
CYRCILE
Phosphatase Spur_PTPN3.AA Subfamily.N_Nematode_egg.PD 390-644 24 9.2e-31 98.4 In-house 6-254 (257) Show / Hide 
Range on Protein: 390-644
Range on HMM: 6-254/257
Sequence Identity: 24% (63 aa)

FDQLYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILRE---ADTGDYINANTINmdipGFDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLT
|..| |    ...  .  ...  | | . .   . .|| |.      ..|.| || ..    |  |.|... || || |||.||| ||....   |||||
feilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvk----Gkpllnefilaqaplkntvedfwrmvfqekvqyivmlt

TNVERgrVKCHKYWPDL-DDRLKF-GPDLEVRCTRCDETPS--FAYRDFIIcNTATKEERIVLQMQYvawpDHgvpDDSSDFLdFVLRVRQCRVGMDVPT
...|    .|. |||   .. |..    |.. . . |. .   |    . .   . .||. .|.    |    . .||   . ||| .    .  |..|.
sakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl-vGgddeelflehwqg----dv---nylsdvy-splrvlrklrnlskpv

IVHCSAGIGRTGVLITMETAMCLIEANePVYPLDIVRT---ERDQRPMLIQTAAQYKFVCEAIIR
.  |. ....|...|.|.. .    |..   . |.    | .|.. .... .| ||   ...   
vvqdilGvskaatlvaieiallsllrG-pitkslvlravvflrlrrrlsvesvllylfvyrlvlf
Phosphatase Spur_PTPN3.AA Subfamily.N_Fungi_PTP1.PD 409-503 37 4.2e-26 82.9 In-house 44-151 (343) Show / Hide 
Range on Protein: 409-503
Range on HMM: 44-151/343
Sequence Identity: 37% (39 aa)

ENVAKNRYRDIAPYDATRVILR-----------EADTGDYINANTINMDIPGFDLVN--KYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVK
|  |||||..| ||. .||.|.              | |||||| ...  .. .     ||.|.|.|||.||.||. .. ...|..||..|| .. ||..
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek

CHKYWPDL
||...   
cyrYWqeg
Phosphatase Spur_PTPN3.AA Subfamily.N_Nematode_eak.PD 393-568 27 3.3e-21 67.0 In-house 9-179 (281) Show / Hide 
Range on Protein: 393-568
Range on HMM: 9-179/281
Sequence Identity: 27% (49 aa)

LYRKKPGMTMGACRLAENVAKNRYRDIAPYDATRVILREAD--TGDYINANTINMDipgfDLVNKYVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVE
| .... ...   .  |.| .||  .| |.|   | |  .      ||||  ...     .. .||. .  .  . |  |||| ||.|  ||.|  .|| 
lddyqrllsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefs----evGrkyiltGiasedkvfafwqmvleqkspaivqlledve

RGRVKCHKYWPDLDDRLKFGpDLEVRCTRC-DETPSFAYRDFIICNtaTKEERIVLQMQYVAWPDHGVPDdSSDFLDFV
.  |  ||.||  . ||.|  |.| .     .   . .| .|.      |   ||  ..  |.  .|    ||| .   
ekleksdkyfpdktevlkyG-ildverkeyavkrniletrllilrk--GnethrvlhykvfGwtettlpk-yedflalr
Phosphatase Spur_PTPN3.AA Subfamily.PTPDC1.PD 548-639 33 2.3e-10 31.5 In-house 138-221 (229) Show / Hide 
Range on Protein: 548-639
Range on HMM: 138-221/229
Sequence Identity: 33% (30 aa)

QYVAWPDHGVPDdSSDFLDFVlRVRQCRVgMDVPTIVHCSAGIGRTGVLItmetAMCLIEANEpVYPLDIVRTERDQRPMLIQTAAQYKFVC
....|.||.      || | .| .  .  .. . ||| || |||||||    |  |. |.. . . . ... |..||  |||  | ..|   
ynfglkDygvas-leriLdiv-kvvdfal-eegkiavHCHAGlGRtGvli----acylvyakr-ltaeeaiklvrskrpksiqtreqvelve
Phosphatase Spur_PTPN3.AA Subfamily.N_Fungi_PTP1.PD 532-605 25 3.1e-09 27.4 In-house 203-286 (343) Show / Hide 
Range on Protein: 532-605
Range on HMM: 203-286/343
Sequence Identity: 25% (21 aa)

IICNTATKEERIVLQMQYVAWPDHGVPDDSSDFLDFVL----------RVRQCRVGMDVPTIVHCSAGIGRTGVLITMETAMCL
.  ..|  |  .|.|.|.  |.| ..  .  ..|  .                      | .||||||.||||.|.|..  .  
tpvtaavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsd
Phosphatase Spur_PTPN3.AA Family.DSP.PD 478-598 19 1.2e-07 22.6 In-house 132-204 (387) Show / Hide 
Range on Protein: 478-598
Range on HMM: 132-204/387
Sequence Identity: 19% (24 aa)

RSTLIVMLTtnvergrvkchkywpdlddrlkfgpdlevrctrCDeTPSFAYrdfiicntatkeeriVLQMQY--VAWPDHGVPDDSSDFLDFVLRVRQCR
. | || ||                                 .|  |.| .                |...|  ....||..|. .. |  ..  .....
gvtkivnlt---------------------------------dd-kpqftk---------------elgikylripidDhnapplenlfekaidfieegn

VGmDVPTIVHCSAGIGRTGVLIT
       ||| ||.||.|.||  
ds-kgvVlVHCkaGkgRsgtlii
Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPN3.AA Protein None 659 None Fasta, JSON
Spur_PTPN3.NA RNA None 1977 None Fasta, JSON
Spur_PTPN3.AA.PD_385-647 Protein Phosphatase Domain None 263 None Fasta, JSON