Spur_PTPN6b
Species: S.purpuratus
Alias: Spur_PTPN6b, Spur_hmm84276, hmm254515
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N6
Protein domain

Protein domains of Spur_PTPN6b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 Spur_PTPN6b.AA SH2 4-87 44 6.7e-28 99.93 SMART 1-87 (87) Show / Hide
Range on Protein: 4-87
Range on HMM: 1-87/87
Sequence Identity: 44% (39 aa)

RRWFHPNISGMEAEQLLLNN-GFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTG-DFFDLYG--GEKFATLAELVQHYTEGRNQ
  |.| |||. ||||||.|. . ||.|| |.| |||||..|||| .|.| |..|. .. . . . .  ..|| .| |||.||.  .  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 Spur_PTPN6b.AA SH2 6-81 49 4.3e-42 125.42 Pfam 1-81 (81) Show / Hide
Range on Protein: 6-81
Range on HMM: 1-81/81
Sequence Identity: 49% (40 aa)

WFHPNISGMEAEQLLLN-NGFDGCFLCRPSKSNPGDFTLSVRRNG---EVTHIKIQNTGDF-FDLYGGEKFATLAELVQHY
|.|..||. |||.||.|  . || || |.| |.|||.|||||..|   .|.|..||.|..  . ..|..||..|.|||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

SH2 Spur_PTPN6b.AA SH2 110-193 44 1.3e-36 128.85 SMART 1-87 (87) Show / Hide
Range on Protein: 110-193
Range on HMM: 1-87/87
Sequence Identity: 44% (39 aa)

ERWFHGHITGKEAEKSLVDK-GKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQD-TKYDVGG--GEQFETLTDLVDHYRKNPMV
. |.||.|...|||. |    ...|..|||.| |.|||||||||...|| |  ||..|  || ...  ...|..| .||.||..|| .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 Spur_PTPN6b.AA SH2 112-187 43 1.9e-43 129.37 Pfam 1-81 (81) Show / Hide
Range on Protein: 112-187
Range on HMM: 1-81/81
Sequence Identity: 43% (35 aa)

WFHGHITGKEAEKSLVD-KGKNGSYLVRESHSKPGDYVLSVRTED---KVTHVMIRCQDTK-YDVGGGEQFETLTDLVDHY
|.||.|...|||. |    ...|..||||| |.||||.||||...   .|.|  |...|.. | ..|...|..| .||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

Phosphatase Spur_PTPN6b.AA Subfamily.N6.PD 229-284 50 5e-12 37.2 In-house 5-53 (295) Show / Hide
Range on Protein: 229-284
Range on HMM: 5-53/295
Sequence Identity: 50% (28 aa)

SRENSKKAGFEEEFEALQLLDNKHLLPRKIGDKAENKSKNRYKNILPYnikvdqlD
| .|.  ||.|||| ||  ....|. || | |.|||.|||||||||.       | 
hrpksqtlgfweefeelqkqeseklysrkegekienkeknryknilPf-------D

Phosphatase Spur_PTPN6b.AA Subfamily.N6.PD 291-449 72 8e-81 263.0 In-house 137-295 (295) Show / Hide
Range on Protein: 291-449
Range on HMM: 137-295/295
Sequence Identity: 72% (116 aa)

NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDFPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPDAGSIIVHCSAGIG
|||.|||||..|||.|||||||.|||.|.|||.|||||.||||. .|.| .|..|||.|||||||.||. |||||.|||||||.. .||.|.||||||||
nkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiG

RTGTFIVIDIILNLIKQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYIE
||||||||||.|..|.|.|||..|||...|. ||.||||||||||||||||.|||.|||
rtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyie

Phosphatase Spur_PTPN6b.AA PTPc 237-449 28 2.4e-61 211.06 SMART 1-308 (308) Show / Hide
Range on Protein: 237-449
Range on HMM: 1-308/308
Sequence Identity: 28% (89 aa)

GFEEEFEALQLLDNKHLL-------PRKIGDKAENK--SKNRYK-NILPYNIKVDQLDS----------------NCVAI--------------------
||.|||| || .... |.       . ..... ||.  .||||| .|..|      | .                | . .                    
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

--------------------------------NKCCRYWPDANTKKDTGVITVTHISEQSMA-DYDLREFSMSHKDF-------PEESRPMFHFHFKSWP
                                .||..||||   ..  | |||| .||.... || .|.|. ....        ..|.| . |.|...||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DHGVPSDPSRVLNFLQDVNKKQETFPD-----------------AGSIIVHCSAGIGRTGTFIVIDIILNLIKQHGLDCEIDIYNTIRLVRQQRSGLVQT
|||||..|. .|.|...|...|...|.                 .| |.||||||.||||||..|||....|..      .||..... .|.|| |.|||
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQT

EAQYKFVYRAVQHYIE
|.||.|.||....||.
EEQYIFCYRCILEYIK

Phosphatase Spur_PTPN6b.AA Y_phosphatase 291-446 40 2.1e-60 211.82 Pfam 86-243 (243) Show / Hide
Range on Protein: 291-446
Range on HMM: 86-243/243
Sequence Identity: 40% (66 aa)

NK-CCRYWPD--ANTKKDTGVITVTHISEQSMADYDLREFSMSHKDF-PEESRPMFHFHFKSWPDHGVPSD-PSRVLNFLQDVNKKQETFPDAG--SIIV
.| | .||||   ....  | ..|| .||....|| .|.|.... .  ..|.| . |.|...|||||||.. |  .|.|.. |.|.|.  ||.|   |.|
EKTCHQYWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-NPDHGCPPIVV

HCSAGIGRTGTFIVIDIILNLIKQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQH
|||||.||||||..|||.. .....|     ||..... .|.|| |.||||.||.|.|.....
HCSAGCGRTGTFCAIDIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Spur_PTPN6b.AA Subfamily.R_Anemone_2.PD 290-448 39 3.1e-47 152.8 In-house 109-261 (262) Show / Hide
Range on Protein: 290-448
Range on HMM: 109-261/262
Sequence Identity: 39% (62 aa)

INKCCRYWPDANTKkDTGVITVTHISEQSMADYDLREFSMSHKDFPEEsRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETfPDAGSIIVHCSAGI
|. ||||. ...   |...|.  .| ...|| ||.|...... .|| | .  ||. ||||.|||.... .|.....|.| |....|| |.||||||.|||
kakvhryWPskgsr-sygklvvelkeevelsdyvlrsfkvkrteeeee-rqvrqfhytsWpdegvpesgaslldlvrqvekaqqe-sgagpivvhcsaGv

GRTGTFIVIDIILNLIKQHGLdceIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|.||..||.|. ||. .|   .|...|.. .|.||. .|||. ||.|.| ... ..   
GrtGvfiavdillerikaeal---vdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase Spur_PTPN6b.AA Subfamily.RB.PD 291-448 36 9.1e-47 151.1 In-house 109-260 (261) Show / Hide
Range on Protein: 291-448
Range on HMM: 109-260/261
Sequence Identity: 36% (57 aa)

NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDfpeESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPDAGSIIVHCSAGIG
.|| .|||. ...   | |.|| ..|... .. .|||......   |.| . ..||.||||||||.... .|.|.. |... |. . .. |.||||||.|
ekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgk---ekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvG

RTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|||||| .| .|. |...     .|.. ..  .|..|  |||||.|| |.........
RtGtfialdrllqaieend---yvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase Spur_PTPN6b.AA Subfamily.R_Anemone_1.PD 291-448 37 2e-46 150.3 In-house 108-257 (258) Show / Hide
Range on Protein: 291-448
Range on HMM: 108-257/258
Sequence Identity: 37% (58 aa)

NKCCRYWPDanTKKDTGVITVTHISEQSMADYDLREFSMSHKDFPeESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKqeTFPDAGSIIVHCSAGIG
.|| .||||  ...  | ..|.  ... .||| .|.. .|.|.   |.| . ..|| .|||.|||.    ||.....|.|...| ...||||||.||||.
kkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkket-eerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvhCsaGvg

RTGTFIVIDIILNLIKQHgldCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|.||| .|. .|..     .||.|... .|..|  .|||. || |...||....    
RtGaflvidamleqakke---kvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase Spur_PTPN6b.AA Subfamily.N12.PD 291-448 37 1.1e-45 147.4 In-house 115-269 (270) Show / Hide
Range on Protein: 291-448
Range on HMM: 115-269/270
Sequence Identity: 37% (60 aa)

NKCCRYWPDANTKKD-TGVITVTHISEQSMA-DYDLREFSMSHKdfpEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQEtfPDAGSIIVHCSAG
.|| ||||. . ..  .| ..|| ..|. .  |. .| . . ..   .||| .  ||...|||||||| ....|.....|.. ||   ..  ..||||||
kkCeryWpeegeeelefgefevtleeekavdddflirtLkveaq---kesrkvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaG

IGRTGTFIVIDIILNLIKQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
.||||| |.||.. .|.|.. .. |.|... .  .|.||. ||||. ||..||.||....
vGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv

Phosphatase Spur_PTPN6b.AA Subfamily.R_Sponge_2.PD 291-449 38 1.5e-43 140.7 In-house 107-262 (262) Show / Hide
Range on Protein: 291-449
Range on HMM: 107-262/262
Sequence Identity: 38% (59 aa)

NKCCRYWPDA-NTKKDTGVITVTHISEQSMADYDLREFSMSHKDFPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETfPDAGSIIVHCSAGI
.|| .|||.. . ... | ..||  .|. .||| .|.. .|...  |... . .||| .||.|.||.| . .|.....|...|...|.|.||.|.|||||
ekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkk-sgnkaitvvCsdgv

GRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYIE
||..|..|. .|. .   |||...... .| .| ||||..|||.|.. |...|||     
grtGtfialdsvlerlkaee---eidvfevlktlrtkriglvqdaaqYvfihdalleyie

Phosphatase Spur_PTPN6b.AA Subfamily.RA.PD 291-448 38 2.4e-43 139.9 In-house 110-265 (266) Show / Hide
Range on Protein: 291-448
Range on HMM: 110-265/266
Sequence Identity: 38% (62 aa)

NKCCRYWPDANTkKDTGVITVTHISEQSMADYDLREFSMS-HKDF--PEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFpDAGSIIVHCSA
.|| .||||  .    | |.|.   |. . || .|.| .    |    ..|| .  |||.|||. |||...  .|..|. |.|.|.    . .|.|||||
ekcaqywpdeGl-vtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqs-anhpivvhcsa

GIGRTGTFIVIDIILNLIKQHGLdceIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|.||||||||.| .|. .|  ..   .|...... .|.||. .|||. ||.|.|.....||
GvGrtGtfivldavlervkaerk---ldvfeavkrlrlqrpqmvqtleqyefiykvlleyi

Phosphatase Spur_PTPN6b.AA Subfamily.RK.PD 280-448 35 3.4e-43 139.2 In-house 102-266 (267) Show / Hide
Range on Protein: 280-448
Range on HMM: 102-266/267
Sequence Identity: 35% (60 aa)

VDQLDSNCVAiNKCCRYWPDaNTKKDTGVITVTHISEQSMADYDLREFSMSH-KDFPEESRPMFHFHFKSWPDH-GVPSDPSRVLNFLQDVNKKQETfPD
...|| .  .  ||..|||. .|..  | | |. .. .  ||.  | |....     || | . .|.| .||.. .||     .|.... |.|.||   .
lteldvevgr-vkClkyWPe-dtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-ee

AGSIIVHCSAGIGRTGTFIVIDIILNLIKQHGLdceIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
.| |.|||.|| ||.||||.|||.|..|...|.   .|..|... .|.... .|.|| |||||| ..  ..
eGrivvhClaGaGrsGtfiaidivlemieregv---vdvfnavktlrnrkvnmveteeqykfvydvileal

Phosphatase Spur_PTPN6b.AA Subfamily.N13.PD 292-445 40 7.8e-43 138.4 In-house 107-255 (259) Show / Hide
Range on Protein: 292-445
Range on HMM: 107-255/259
Sequence Identity: 40% (63 aa)

KCCRYWPDANTKKDT--GVITVTHISEQSMADYDLREFSMSHKDfPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQEtfpDAGSIIVHCSAGI
|| ||||. . || .  . ..|. .  | . .. .|.. .....  .||| . |..| .|||||||| .  ...|...|.. |.   ||| |.|||||||
kchrywPerknkklkvsnrlevellkvqkldgfvvralavkdse-sgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dagPivvhcsaGi

GRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQ
||.|..|.||..|.||...    |.|. ...| .|.|| |.|||. || |||.|. 
GrsGvlitidvvlglierdk---efdvkeivrklreqrqgvvqtkdqyifvykail

Phosphatase Spur_PTPN6b.AA Subfamily.N_Choan_1.PD 292-448 34 3.3e-42 136.2 In-house 110-261 (262) Show / Hide
Range on Protein: 292-448
Range on HMM: 110-261/262
Sequence Identity: 34% (54 aa)

KCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDfpEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPDaGSIIVHCSAGIGR
|| ||||| |..   | .||...||.. . |  |.|......   |.| . ......|||||||.... .|.| ..|.| ...  .....|||||.||||
kChryWPdenselklgdvtvkslseeekktyierkfkleres--getreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvihCsaGvGr

TGTFIVIDIILNLIKQHGldCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|.| .| ... ....    ..|. .... .|..|  .||| .||.|||.||....  
tGtyialDrlvkaveeka--ealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase Spur_PTPN6b.AA PTPc_motif 340-446 39 3.9e-42 147.22 SMART 1-92 (92) Show / Hide
Range on Protein: 340-446
Range on HMM: 1-92/92
Sequence Identity: 39% (44 aa)

PMFHFHFKSWPDH-----GVPSDPSRVLNFLQDVNKKQETFPDAGSIIVHCSAGIGRTGTFIVIDIILNLIKQHGLDCEIDIYNTIRLVRQQRSGLVQTE
 . |.|. .||||     |||.  . .| |.. |.|         .|.||||||.||||||..||.....         .||..|.. .|.|| |.||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQTE

AQYKFVYRAVQH
.||.|.||... 
EQYIFCYRCILE

Phosphatase Spur_PTPN6b.AA Subfamily.N9.PD 291-447 40 6e-41 132.2 In-house 109-273 (275) Show / Hide
Range on Protein: 291-447
Range on HMM: 109-273/275
Sequence Identity: 40% (64 aa)

NKCCRYWP-DANTKKDTGVITVTHISEQSMADYDLREFSMSHKDfPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETF-----------PDA
|| .||| . ..... | ..|.... ... ||  | . ... .  |||| . || | ||||.||||. . .|..|. | .|| ....   |.||||||||
lkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvk-teesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsg

GSIIVHCSAGIGRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHY
|||||| .|| |. ... |    .|. .|..|.|.||.  .||. ||.| | ||  |            
PPivvhcsaGiGrtGtfitldiclarleevg---tvdvvetvkllrtqrafsiqtpeqyefcylavley

Phosphatase Spur_PTPN6b.AA Subfamily.N_Choan_2.PD 291-449 34 8.6e-40 128.1 In-house 105-266 (266) Show / Hide
Range on Protein: 291-449
Range on HMM: 105-266/266
Sequence Identity: 34% (58 aa)

NKCCRYWPDANTK---KDTGVITVTHISEQSMADYDLREFSMSHkdfPEESRPMFHFHFKSWPDHGVPSDPS------RVLNFLQDVNKKQETFPDAGSI
.|| ||||  . .     .| |.|. .||. .  | |..  . .    .|.| . ||....|||||||...        .|. |..|.. .. . .|. .
kkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlek---kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePl

IVHCSAGIGRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYIE
.||||||.|||||.|.|||...|.....   ..|. . |. .|..|  |||.  ||...|.||..|.|
lvHcsaGvgRtGtliaiDiavrlLeetk---kvdvlaiieelRkdRmalvqhpeqyellykavveyae

Phosphatase Spur_PTPN6b.AA Subfamily.N5_RR.PD 291-448 30 2.5e-39 126.8 In-house 108-264 (265) Show / Hide
Range on Protein: 291-448
Range on HMM: 108-264/265
Sequence Identity: 30% (48 aa)

NKCCRYWPDANTK---KDTGVITVTHISEQSMADYDLREFSMSHKDFpeESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPDA-GSIIVHCS
.|| .|.|||.     .  | . ..  .  .  || .|......      .| . |. . .|||| .| |.. .|.....|....|.. ..|||||||||
qkcavyfPdaedyeiserygdveikveeiverndysvrklvlkyler--versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcs

AGIGRTGTFIVIDIILNLIKQhglDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|| || |.| .. ...   .  .|. ...  .|..| |.|||. ||....||. .|      
aGiGrtGcfiaisiavrqlre---eivvdvlkivcnlrldrGGmvqtseqyelihralclyl

Phosphatase Spur_PTPN6b.AA Subfamily.N3.PD 291-444 36 1.1e-38 124.5 In-house 109-256 (261) Show / Hide
Range on Protein: 291-444
Range on HMM: 109-256/261
Sequence Identity: 36% (56 aa)

NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDFpEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPDagSIIVHCSAGIG
||..|||. . . . | ..|.  .|..   | |||. ...|.  .|.| .... . .|||||||.|.. .|.|.. |.|....  .   ..|||||||||
vkChqyWPetedelefgefsvrcekedetksyvlrelvlkdket-keerkilqlqylaWpdhgvPddsadflefvervrklrsgkee--PvvvhCsaGig

RTGTFIVIDIILNLIKQHgldCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAV
|| .|.... | || ..    .. . . .| .|.||. ||||..|||||  |. 
rtGvlilletalalieaa---epvypldivrtmrdqramlvqtvsqykfvCeai

Phosphatase Spur_PTPN6b.AA Subfamily.R_Ecdysozoa.PD 291-448 33 1.3e-37 121.0 In-house 108-268 (269) Show / Hide
Range on Protein: 291-448
Range on HMM: 108-268/269
Sequence Identity: 33% (55 aa)

NK-CCRYWPDAnTKKDTGVITVTHISEQSMADYDLREFSMSHKD--FPEESRPMFHFHFKSWP-DHGVPSDPSRVLNFLQDVNKKQET---FPDAGSIIV
|. | .|||.  ...  | | |. .||... ||  ||...|.|.    |.|| .  .....|. |  ||  .  .|.... |.....       . |.||
nrkcakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivv

HCSAGIGRTGTFIVIDIILnliKQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|||| ||.|.|. .|..|   .|  .. ..||..|.. .|.||. |||  .||.|.|||. .|. 
hCsaGvgrsgifvaldlll---qqlkaedkvdifetvkkLrsqrnllvqsleqyvflyraladys

Phosphatase Spur_PTPN6b.AA Subfamily.RG.PD 291-447 31 1.1e-36 118.2 In-house 110-262 (264) Show / Hide
Range on Protein: 291-447
Range on HMM: 110-262/264
Sequence Identity: 31% (50 aa)

NKCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDFPEESR-PMFHFHFKSWPDHGVPSDPSRVLNFlqdVNKKQETF-PDAGSIIVHCSAG
... .|||. ..  ... ..|| .|.. ...| .|.|.. .... .|..  . ..|. .|||.|.|.    ||.|   |.|.. .   .|| |.||.|||
rdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlif---vkkeeaankeeaGPivvhdsaG

IGRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHY
 ||.||.|..| .|. ....     ...|....|.|..| |||.|| ||.|.| |... 
vgragtyialdtllqqlekee---avnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase Spur_PTPN6b.AA Subfamily.RN.PD 289-446 37 6.3e-35 112.2 In-house 109-261 (264) Show / Hide
Range on Protein: 289-446
Range on HMM: 109-261/264
Sequence Identity: 37% (60 aa)

AINKCCRYWPDANTkKDTGVITVTHISEQSM-ADYDLREFSMSHKDfPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETfpDAGSIIVHCSA
...| |||||  . .  ..  |  .||     || .| | .   .  .|.| .  ||| |||..|||. .  .|.| . |||       . .|.||||.|
gvkqckrywpdeGs-evyhiyevhlvsehiwcddylvrsfylknlq-tsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG--rscpivvhcsd

GIGRTGTFIVIDIILNLIKQhGLDcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQH
 ||||..|.||..|. ... |.  ||||  |.  .|.||.|||.|..|..|.. || . 
GaGrtGvyilidlvlerllk-Gvk-eidiaatlehlrdqrpglvktkdqfefaltavae

Phosphatase Spur_PTPN6b.AA Subfamily.N1.PD 291-444 34 2.2e-32 104.1 In-house 107-263 (268) Show / Hide
Range on Protein: 291-444
Range on HMM: 107-263/268
Sequence Identity: 34% (54 aa)

NKCCRYWPDANTK----KDTGVITVTHISEQSMADYDLREFSMSHKDfPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPDAGSIIVHCS
.||  |||  . .     ..  ..|. |||.    . .| . .  ..  .|.| ..|||.  ||| |||. |. .|.||. | .     .| |....|||
ikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLedle-tqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCs

AGIGRTGTFIVIDIILNLIKQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAV
|||||.||. ..| .| .| ..|    .|| . .  .|..| ||.||  | .| | |.
agigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiai

Phosphatase Spur_PTPN6b.AA Subfamily.N14.PD 291-448 34 5.5e-32 102.6 In-house 110-274 (275) Show / Hide
Range on Protein: 291-448
Range on HMM: 110-274/275
Sequence Identity: 34% (55 aa)

NKCCRYWPDANTKKDTGV---ITVTHISEQSMADYDLREFSMSHKDfPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPD--------AG
.|. .|.|. . ||.|       ||    ..   .  . . . |    .| | ..|. .. |||||||.|..  |.||..|.  .. . ...||||||.|
eksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlp-skeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskP

SIIVHCSAGIGRTGTFIVIDIILNLIKQhglDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|||  |. |.... ...   . |||| .... .|.||  |||| |||||||... .|.           
PvlvhCsaGvGrtGvlilsdlliatleh---neeidikkvlarLrkqrmllvqtlaqykfvykvlikyl

Phosphatase Spur_PTPN6b.AA Subfamily.RC.PD 291-447 25 3.6e-31 100.0 In-house 128-286 (288) Show / Hide
Range on Protein: 291-447
Range on HMM: 128-286/288
Sequence Identity: 25% (42 aa)

NKCCRYWpdANTKKDTGVITVTHISEQSMADYDLREFSMSHKDFpEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKK------QETFPD--AGSII
.|| .||   . |.  | . |    ..  .|| || . . .|    .|| .... . ||.....| .|  .|...| |..|       |.| ... ..||
ekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkr-kdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpll

VHCSAGIGRTGTFIVIDIILNlikQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHY
|..| .|||.|| .. .|.       .  .|... .. .|..|...|..|.||...| .. ..  
vhcrdGsqrtGifiallalle---sleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet

Phosphatase Spur_PTPN6b.AA Subfamily.N23.PD 291-447 34 5.9e-31 99.3 In-house 187-348 (350) Show / Hide
Range on Protein: 291-447
Range on HMM: 187-348/350
Sequence Identity: 34% (56 aa)

NKCCRYWPDANT-KKDTGVITVTHISEQSMADYDLREFSMSHKDFpEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQ------ETFPDAG-SII
|| .||| ..   .  | ..|.  |..|   .  | ....|.|  .  | . |.|...|...|||. |. .|.||..|..        ||..|  ||.||
lkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndv-stvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPii

VHCSAGIGRTGTFIVI-DIILNLIKQHGLDceiDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHY
|||.|||||| |.  .| .| ...|.    .| . .| .||||   ||.....|..|.|| ..   
lhCsaGvgRtgtfcvvysaireltagngii---niprvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase Spur_PTPN6b.AA Subfamily.N_Nematode_1.PD 290-448 32 8.9e-27 85.5 In-house 106-264 (265) Show / Hide
Range on Protein: 290-448
Range on HMM: 106-264/265
Sequence Identity: 32% (53 aa)

INKCCRYWPDANTKKDT-----GVITVTHISEQSMA--DYD-LREFSMSHKDFPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQetfpdaGSI
||. |.| .. .| .       ||| . .. ..   | . ...  .. .   |..| . |.... |||.|||.    .|..|..|....      | |.|
kkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk------gPi

IVHCSAGIGRTGTFIVIDIILNLIKQhGLDCEiDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
||||||||||| ..|. ||. . . |  .| |. . .. .|.||.  .||.||| ||.| . .|.  
vvhCsaGiGrtGtivaieyildklle-gkqie-dmeklvkkireqrnysiqtdaqylfvhrvllnyf

Phosphatase Spur_PTPN6b.AA Subfamily.N_Nematode_4.PD 289-444 28 7.8e-26 82.5 In-house 104-259 (264) Show / Hide
Range on Protein: 289-444
Range on HMM: 104-259/264
Sequence Identity: 28% (46 aa)

AINKCCRYWPDANTK-KDTGVITVTHISEQSM--ADYDLREFSMSHKD----FPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETFPdagsI
..|| ||.|. . | .. |   .| . .. .  ||  |. . ..  .     | |   . |.... |.|.  | |.  |..... |.||..  |    |.
gvekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekP----i

IVHCSAGIGRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAV
||||||.||| |.. ||.    |.. .   ||.. . .| .|. | . ||.. |. |..  . 
vvhcsaGvGrtatlvGidyatirirens---eievldivrelramrlkavqshlqflfllvvl

Phosphatase Spur_PTPN6b.AA Subfamily.R_Nematode_3.PD 290-444 26 9.5e-26 82.2 In-house 115-262 (267) Show / Hide
Range on Protein: 290-444
Range on HMM: 115-262/267
Sequence Identity: 26% (41 aa)

INKCCRYWPDAN-TKKDTGVITV--THISEQSMADYDLREFSMSHKdfPEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQeTfpdagSIIVHCS
.||..|.|..  ..   . ..|  |.|...  .| . |.. .. .   ..   . | ..|.|.....| .|  .|. .. |.|. |     ...||||.|
eekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfe--kkkeftvthllykgWkelnapeepkealelikfveksk-t-----pvvVHCs

AGIGRTGTFIVIDIILNLIKQH-GldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAV
|.|..|. .|..  .|| .. |   ..|. . |  .|.|| | .||| .. ||   .  
dGisRsatlaaielgyqliikskg---kldllslikelrkqRagaiqtelelafvilgi

Phosphatase Spur_PTPN6b.AA Subfamily.N_Nematode_6.PD 291-448 33 2.1e-25 81.1 In-house 103-252 (253) Show / Hide
Range on Protein: 291-448
Range on HMM: 103-252/253
Sequence Identity: 33% (53 aa)

NKCCRYWPDA--NTKKDTGVITVTHISEQSMADYDLREFSMSHKDFPEESrPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQEtfPdagsIIVHCSAG
.|...| .|   ...| | . ||..|.....     |      |.  ||.  . |.|...||||||| .    | .|. | |..|    |.||||||.||
eksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeev-ivkhihWanWPdhGvPdsflsalrllsvvkkdkk--P----ivvhCsaG

IGRTGTFIVIDIILNLIKQHGldcEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
|||...| |||. ...      ... . . ..|..|   |||| || ...| |  |.   
vGrtGtlaliliilealrlpd---fqgvkdllvklreerfravqtevqylyalrcvleyl

Phosphatase Spur_PTPN6b.AA Subfamily.N20.PD 289-444 33 2.5e-24 77.8 In-house 104-252 (257) Show / Hide
Range on Protein: 289-444
Range on HMM: 104-252/257
Sequence Identity: 33% (52 aa)

AINKCCRYWPDANTKK-DTGVITVTHISEQSMADYDLREFSMSHKDFpEESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQETfpdaGSIIVHCSA
| || .||| .  |  .   . |     | .  . .| | .  |     |. . ...|  ||||| |.    ......   | . |    |..|||||||
giikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekst-gtshsvkqlqftkwpdhgtpasadsfikyiryarkshlt----gpmvvhcsa

GIGRTGTFIVIDIILNLIKQhglDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAV
|||| |...|...  | .   .| ..| . .  .|.||||.|||. ||.|.|  |  
gigrtgvflcvdvvfcaivk---ncsfnimdivaqmreqrsgmvqtkeqyhfcydiv

Phosphatase Spur_PTPN6b.AA Subfamily.R_Nematode_2.PD 290-443 27 4e-23 73.5 In-house 108-255 (261) Show / Hide
Range on Protein: 290-443
Range on HMM: 108-255/261
Sequence Identity: 27% (42 aa)

INKCCRYWPDANT-KKDTGVITVTHISEQSMADYDLREFSMSHKDFPE--ESRPMFHFHFKSWPDHGVPSDPSRVLNFLQDVNKKQEtfPdagsIIVHCS
.|| .|.|  .. | | | ....  |...... .. . ..  .|     ..| . |. ...|||.|||     . . |. | |..  |    |.||||||
kekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek--P----ivvhCs

AGIGRTGTFIVIDIILNLIKQhglDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRA
||||..|| .. . . ...   | .| . .... .|..|.  .||| |. .. ..  
aGiGRtmafigteylarevea---dptieltealkelrehRwkgiqtesqlywltlg

Phosphatase Spur_PTPN6b.AA Subfamily.N_Nematode_5.PD 341-448 25 2.7e-19 60.9 In-house 154-257 (258) Show / Hide
Range on Protein: 341-448
Range on HMM: 154-257/258
Sequence Identity: 25% (28 aa)

MFHFHFKSWPDHGVPSDPSRVLNflQDVNKKQETFPDA-GSIIVHCSAGIGRTGTFIVIDIILNLIKQHgldCEIDIYNTIRLVRQQRSGLVQTEAQYKF
. . |.. |... ||.. . |..   ...|  ..  ..  ...|....|.||.|||...... . ...     |..| .... .|.|| | |.. .|| .
akvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnng---kepnideilkkirsqRpgavesliqyas

VYRAVQHYI
||.||  ||
vyaavldyi

Phosphatase Spur_PTPN6b.AA Subfamily.N_Fungi_PTP1.PD 338-448 25 8.6e-19 59.2 In-house 212-342 (343) Show / Hide
Range on Protein: 338-448
Range on HMM: 212-342/343
Sequence Identity: 25% (32 aa)

SRPMFHFHFKSWPDHGVPSDPSRVLNFLQ------DVNK-KQE-TFPDAGSIIVHCSAGIGRTGTFIVIDIILN------LIKQHGLDCEI------DIY
......| |.| ..  .|  .|. |.      | .  ..      . .|.||||||.|||||.. .| .|.       ....    .        |  ..
pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlis

NTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
  .|.||  .||.  |. |.| |...|    
iivnelrkqrismvqnldqfifiYeallfyf

Phosphatase Spur_PTPN6b.AA Family.DSP.PD 301-452 16 2.2e-14 45.1 In-house 129-251 (387) Show / Hide
Range on Protein: 301-452
Range on HMM: 129-251/387
Sequence Identity: 16% (26 aa)

NTKKDTGVITVThiseqsmadydlrefsM------ShkdfpeesRPMFHFHFKSWPDHGVPSDPS---RVLNFLQDVNKkqetfpDAGSIIVHCSAGIGR
.... | .. .|                       .        .  ....  ...||..|.  .   ....|....|.      . | . ||| ||.||
kelgvtkivnlt----------------ddkpqftk--------elgikylripidDhnapplenlfekaidfieegnd------skgvVlVHCkaGkgR

TGTFIVIDIILNlikqHGLDCEidiyNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYIETLS
.|| |.. .. .    .||  |     ....||..|.| .. . ...  . . .. . ..|
sgtliiaYlmks----egltle----ealdwvrskRpgvitpnqgflkqlkdlekeklkvs

Phosphatase Spur_PTPN6b.AA Subfamily.PTPDC1.PD 327-441 30 1.7e-11 35.6 In-house 123-221 (229) Show / Hide
Range on Protein: 327-441
Range on HMM: 123-221/229
Sequence Identity: 30% (33 aa)

FSMSHKDFPEESrpMFHFHFkSWPDHGVPSdpsrvLNFLQDVNKKQETFPDAGSIIVHCSAGIGRTGTFIVIDIILnlikQHGLDCEidiyNTIRLVRQQ
|| .  .. ..   .... | ...|.||.|     |. . |. |  .     | | ||| || ||||  |   ..     .. |. |. |.|||..|.  
fsYdpeelmrqg--iyfynf-glkDygvas-----leriLdivkvvdfaleegkiavHCHAGlGRtGvliacylvy----akrltae----eaiklvrsk

RSGLVQTEAQYKFVY
.||  | ..|     
rpksiqtreqvelve

Phosphatase Spur_PTPN6b.AA Subfamily.N_Nematode_egg.PD 285-449 22 4e-11 34.3 In-house 106-257 (257) Show / Hide
Range on Protein: 285-449
Range on HMM: 106-257/257
Sequence Identity: 22% (38 aa)

SncvaiNKCCRYWPDANTKKDT---GVITVTHISEQSMADYDlreFSMSHKDF---PEESRPMFHFHFkSWPDHGVPSDPSRVLNFLQDVNKkqetfPda
|     ..|  ||| |...      | . .. .  .| ||     | ...       .| . . |.    .   .    | |||  |... |     |  
s-----erceyywpkaeseslvtvpGslrienlkvdskadpl---frvtklklvGgddeelflehwqg-dvnylsdvysplrvlrklrnlsk-----p--

gsIIVHCSAGIGRTGTFIVIDIIL-NLIKqhGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYIE
  ..|..  |. ...|.. |.| | .|..  |      . ... ..|..|   |..  .| |||| | ..|.
--vvvqdilGvskaatlvaieiallsllr--Gpitkslvlravvflrlrrrlsvesvllylfvyrlvlffir

Phosphatase Spur_PTPN6b.AA Subfamily.N_Nematode_eak.PD 363-448 27 4.4e-11 34.1 In-house 196-280 (281) Show / Hide
Range on Protein: 363-448
Range on HMM: 196-280/281
Sequence Identity: 27% (23 aa)

NFLQDVNKKQETFPDAGSIIVHCSAGIGRTGTFIVIDIILNLIKQHGlDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYI
. |. . ||    | . . |. .. |  |.|.|.|||....|| ..       . . |  |...|   | .. |. |.| .|.|. 
allrstlkkyihtppsfapiiqsarGsaraGvfvvidllirlidnkk-knlysvedlilkvkskrihsvlvalqhsfiyeivldyl

Phosphatase Spur_PTPN6b.AA Subfamily.DSP23.PD 343-442 28 5.1e-09 27.8 In-house 35-124 (128) Show / Hide
Range on Protein: 343-442
Range on HMM: 35-124/128
Sequence Identity: 28% (28 aa)

HFHFKSWPDHGVPSdPSRVLNFLQDVNKKQEtfpDAGSIIVHCSAGIGRTGTFIVIdiilNLIKQHGLDCEidiyNTIRLVRQQRSGLVQTEAQYKFV--
..  . ||.  |. . .| .... |.. ..     ... |||  |.|||||..       |.|..||  .    ..|  ||..| | ..|| | |  |. 
tlrridipdfcPPa-leqvarlvriveeaek---keeavgvhcalGlGrtGtllac----ylvkeeglaad----daiaevrkrrkGsietveqekavkd

YR
  
ye

Phosphatase Spur_PTPN6b.AA Subfamily.CDC14.PD 353-435 35 8.2e-08 23.7 In-house 180-247 (258) Show / Hide
Range on Protein: 353-435
Range on HMM: 180-247/258
Sequence Identity: 35% (29 aa)

GVPSDpSRVLNFLQDVNKKqetfpdAGSIIVHCSAGIGRTGTFIVIdiilNLIKQHGLDCEidiyNTIRLVRQQRSGLVQTEA
.|||| . . .||. ..|        |.|.||| ||.|||||.|       |||....  .    .||  .|  | | | .  
tvPsd-ailkkfleiteka------eGaiavhCkaGLGrtgtligc----ylikhyrftaa----etiawlriarPGsvigpq

Phosphatase Spur_PTPN6b.AA Subfamily.PTEN.PD 361-425 27 2.5e-07 21.9 In-house 78-140 (305) Show / Hide
Range on Protein: 361-425
Range on HMM: 78-140/305
Sequence Identity: 27% (18 aa)

VLNFLQDVNKKQETfPDAGSIIVHCSAGIGRTGTFIVIDIILNLIKQHGLDcEIDIYNTIRLVRQ
. .. .||.|  .   .   ..||| || ||||. |.  .. ..||... .  ..||.  |   .
leeivedvdkwLke-dksnVvavHCkaGkGRtGvmicayLlksgikksade-alaiydekRtkdk

Phosphatase Spur_PTPN6b.AA Subfamily.N13.PD 239-290 42 1.2e-06 19.7 In-house 3-52 (259) Show / Hide
Range on Protein: 239-290
Range on HMM: 3-52/259
Sequence Identity: 42% (22 aa)

EEEFEALQLLdnKHLLPRKIGDKAENKSKNRYKNILPYNIKVDQLDSNCVAI
.|||. |. |  | |.  ..| |.|||.||||.|.|||.    .|...   |
aeefkelrel--kpldtcevgkkkenkdknryrnvlPydetrvklgdeggyi

Phosphatase Spur_PTPN6b.AA Subfamily.N12.PD 238-279 41 1.8e-06 18.8 In-house 2-47 (270) Show / Hide
Range on Protein: 238-279
Range on HMM: 2-47/270
Sequence Identity: 41% (19 aa)

FEEEFEALQLLDNK----HLLPRKIGDKAENKSKNRYKNILPYNIK
|..||..|. | .|    .  ... |.| ||. |||||.||||. .
fakefqklkklsekykaekvysteagekeenvkknrykDilPydks

Phosphatase Spur_PTPN6b.AA Subfamily.RC.PD 239-279 48 1.9e-06 18.8 In-house 3-41 (288) Show / Hide
Range on Protein: 239-279
Range on HMM: 3-41/288
Sequence Identity: 48% (19 aa)

EEEFEALQLLDNKhlLPRKIGDKAENKSKNRYKNILPYNIK
| ||. |  .  |   . ||. | |||||||| ..|||.  
eaefqrlpsvrsk--rtikiarkeenksknrysdvlpydyn

Phosphatase Spur_PTPN6b.AA Subfamily.PRL.PD 351-439 25 4.4e-06 18.1 In-house 56-132 (140) Show / Hide
Range on Protein: 351-439
Range on HMM: 56-132/140
Sequence Identity: 25% (23 aa)

DHGVPSDpSRVLNFLQDVNKKQETFPDaGSIIVHCSAGIGRTGTFIVIDIIlnlikQHGLDCEidiyNTIRLVRQQRSGLVQTeAQYKF
| .||.. . | ..|. ...| .  |.  .. ||| ||.||.  .. . .|     ..|.. |    ... ..|..| | . .  | ||
dGavPpk-evvdeWlellkekfkeepk-stvavhcvaGlGraPvlvalali-----eaGmkye----davefirekrrgains-kqlkf

Phosphatase Spur_PTPN6b.AA Subfamily.DSP19.PD 361-413 30 9.5e-06 17.0 In-house 68-110 (139) Show / Hide
Range on Protein: 361-413
Range on HMM: 68-110/139
Sequence Identity: 30% (16 aa)

VLNFLQDVNKKQetfpdaGSIIVHCSAGIGRTGTFiVIDIilnLIKQHGLDCE
.|.|.... .|.      | ..|||.||. |. .. ||     |.|.. |..|
aldFieearskd------grvlvHCnAGvSRsasv-viay---lmkdeelsle

Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPN6b.AA Protein None 533 None Fasta, JSON
Spur_PTPN6b.NA RNA None 1599 None Fasta, JSON
Spur_PTPN6b.AA.PD2_496-507 Protein Phosphatase Domain None 12 None Fasta, JSON
Spur_PTPN6b.AA.PD1_237-449 Protein Phosphatase Domain None 213 None Fasta, JSON