Spur_PTPRB3
Species: S.purpuratus
Alias: Spur_PTPRB3, Spur_hmm138970, hmm175230
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of Spur_PTPRB3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Fn3 Spur_PTPRB3.AA FN3 7-91 21 3.2e-12 47.83 SMART 1-69 (69) Show / Hide
Range on Protein: 7-91
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PQPPGN---VAVTEETTS------TITLSWSPPSQEQFFGYILEYEGTGFSTELGRTPATSFLPRHQESVTLKGLTPG----ISYSIKISSFVE--YDDV
| ||.|   . ||. |..      ..||||.||        |..|.                       .|..||.||      |..... . .  .   
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG





Fn3 Spur_PTPRB3.AA FN3 191-269 18 2.7e-07 31.49 SMART 1-69 (69) Show / Hide
Range on Protein: 191-269
Range on HMM: 1-69/69
Sequence Identity: 18% (18 aa)

PSAVSN---VDVVPEAA-------ALTLSWDPVFGDVDGYYASYQLKEDPYQISDLFYVSDPSNPTIRLTGLSPL----SEYIITLTSF----SGSG
|....|   . |..  .        .||||.|    . ||                           ..|||.|     .|| .... .     |.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR-------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 343-421 17 7e-06 26.75 SMART 1-69 (69) Show / Hide
Range on Protein: 343-421
Range on HMM: 1-69/69
Sequence Identity: 17% (16 aa)

PTAPRS---LSTDSISQS------IVTVSWSQGLGNVDEYDIYLRQAGESETPAQIVPPSQLTETFENLEPD----TYYSMRIVSVVR--AQNL
| .|.    |.  ... .       ||.||.     . .|                        |...|.|.    | |. |.. | .  |   
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 699-775 18 4.2e-09 37.48 SMART 1-69 (69) Show / Hide
Range on Protein: 699-775
Range on HMM: 1-69/69
Sequence Identity: 18% (17 aa)

PLAPGT---PLATQVLDT------SIQLQWAQSSDGNVAGYEICYSPDDGSSPVYIAGRTTTQYTLEGLDSD----TTYIISISAL----TGVP
| .|.    . .| | .|      |..|.|           .. |.                 ||..||  .    |.| ....|      |  
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR-----------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 883-962 19 4e-09 37.55 SMART 1-69 (69) Show / Hide
Range on Protein: 883-962
Range on HMM: 1-69/69
Sequence Identity: 19% (18 aa)

GQIAVNNLIVVIGERTTT------SLEILWGASASGSVDEYQVSYVGSTPIVVDGSSDRRVVIPGLSPG----TEYTVTVQAINA-GAAVG
     |. .... . |.|      |... | .     . .|.                  ....||.||    |||...|.|.|. .|  |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 1247-1323 20 3.3e-08 34.52 SMART 1-69 (69) Show / Hide
Range on Protein: 1247-1323
Range on HMM: 1-69/69
Sequence Identity: 20% (19 aa)

DPGDIN---IALEDVDTN------SVRITWVAINSITRYTVGGGTGASQTVTVNSPEEAEYTFTNLVPG----TSYTFFVTPLG-TQRRER
 .   |   . ..||...      ||...| .   |..|.                    ||.|.|.||    | |.| |.    ... | 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 1329-1412 21 1.3e-13 52.44 SMART 1-69 (69) Show / Hide
Range on Protein: 1329-1412
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PDMPRN---LLFNTITTN------SISIGWEKPLTGGVDSYRVTYSPSSDGSPASPHTITDNGQITQTLTVTNLLPG----TTYTFNVYALVA--ELVS
|. |.|   | .  .|..      |... |..|    . .||                           |||.| ||    |.|.| |.|  .     .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----IVGYR--------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 1812-1890 22 6.6e-12 46.81 SMART 1-69 (69) Show / Hide
Range on Protein: 1812-1890
Range on HMM: 1-69/69
Sequence Identity: 22% (21 aa)

SKPPQN---LMQDEVTSD------SITVSWGAPLNVVNMYHIIVKDEDGADVADATVPSSETSYTIENLNPY----TKYIITVAARFN--GLDS
  ||.|   |   .|||.      |.|.|| .|  .|.                         ||...| |.    |.| ..|.|.    .  .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB3.AA FN3 1904-1993 16 2e-11 45.17 SMART 1-69 (69) Show / Hide
Range on Protein: 1904-1993
Range on HMM: 1-69/69
Sequence Identity: 16% (17 aa)

PSVVRD---PVVAINSPN------SVFLTWTPPDSPNGILTGFVVEITGEDLTSRKRREAGFTRTETYGVTVFSATIENLPTG----CSYTFSIKAANS-
|. ...   ..|   ...      || |.|.||       .|..                              .|...|  |      |.|...| |. 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR------------------------------YTVTGLKPGQYPWTEYEFRVRAVNGN

-ADQS
 | ..
DAGEG

Phosphatase Spur_PTPRB3.AA Subfamily.N6.PD 2278-2539 38 7.1e-72 233.6 In-house 10-292 (295) Show / Hide
Range on Protein: 2278-2539
Range on HMM: 10-292/295
Sequence Identity: 38% (108 aa)

NNTGFVEEYNSLS--NVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEE-GQTSDYINANYI----------QGLHSM---KEYIASQGPVPDS
.  || ||...|.  .. . .| . .. . |..||||.||||||.| | |.| |.  . |||||||||          .  .|    |.|||.||...| 
qtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdt

VNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPDDDTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKG---MQQFETHQYAFKGWVDHDVPNNARPMIE
|.|||.||....|. | |.|  || || || .||||  |  ..|..|||... ......|.| |....     .. | .|| ||| ||.||...  ...|
vsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvln

FIRTIDVAHDA--NLGPITVHCSAGIGRTGVFIALHKLIKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLL
.. ..  ...  . ||| ||||||||||| || .  ..|..|.|. .  ||.  .. ..|.|| ..||| .|| |. ...   
fledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf

Phosphatase Spur_PTPRB3.AA Subfamily.RB.PD 2282-2541 50 2.2e-112 366.1 In-house 2-260 (261) Show / Hide
Range on Protein: 2282-2541
Range on HMM: 2-260/261
Sequence Identity: 50% (132 aa)

FVEEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMIT
| |||..|..||.|....|...||| .|||..||||.|.. |.|..|.. ...||||||||.| .|..||||.|||.|..|.|||.||.|.||..| |.|
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

GLVEGGKTKCEHYWPDDDTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDAN--LGPITVHCS
 |||.||.|||.|||.|..||.||...||.....|...|..|.| .|||... . .|| |. | ||.||........|.||..|....   .|| |||||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCs

AGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLLM
|.||||.||||..|....|.   |||.||.|.||..||.| ..||| |||.|||.||| |. 
aGvGRtGtfialdrllqaiee---ndyvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase Spur_PTPRB3.AA PTPc 2281-2542 31 3.7e-109 369.85 SMART 1-308 (308) Show / Hide
Range on Protein: 2281-2542
Range on HMM: 1-308/308
Sequence Identity: 31% (99 aa)

GFVEEYNSLSNVGRDK---------STDASRLAVNA--TKNRYR-NILPFDETAVHLQDLEEG----QTSDYINANYIQGLHSMKEYIASQGPVPDSVND
|| ||...| ... ..         |.. ...  |.  .||||. .|...|.| |.|.....     . ||||||||| | .. |.||. ||| |. ..|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWEMVFENKSTTIAMITGLVEG--------GKTKCEHYWPDDDTPVNYGSVTVTMTHTQEME-QWTVRSFLLEKGM----------QQFETHQYAFKGWV
|| ||...|...|.|.. ..|.        |. ||..||||.  |..||  |||.. .. ..  .|.| | ....           .  . ..| ...| 
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DHDVPNNARPMIEFIRTIDVAHDAN-------------------LGPITVHCSAGIGRTGVFIALHKLIKQVETSKPNDYIDVCGTVARMREQRFNMVQT
||.||........|||...  .  .                    ||| ||||||.||||.|.|.  .. |.|.      .|....| .||.||..||||
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQT

VKQYMFIHQCLLLLMR
  ||.|...|.| . .
EEQYIFCYRCILEYIK

Phosphatase Spur_PTPRB3.AA Y_phosphatase 2306-2539 39 4.3e-101 346.96 Pfam 1-243 (243) Show / Hide
Range on Protein: 2306-2539
Range on HMM: 1-243/243
Sequence Identity: 39% (97 aa)

NATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQG-LHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGK-TK-CEHYWPD--DDT
|  ||||..|...| | |.||...... ||||||||| |  .. |.||. ||| |....||| ||...|.|.|.|.. ..|.|.  | |..||||  ...
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PVNYGSVTVTMTHTQEMEQWTVRSFLLEKGM----QQFETHQYAFKGWVDHDVPNN-ARPMIEFIRTIDVAHD-ANLG--PITVHCSAGIGRTGVFIALH
|..||  .||.. ..... .||| | ...      .  . ..| ...| ||.|| . ...|..||| .  ..   . |  ||.||||||.||||.|.|. 
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

KLIKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLL
 .. |.|...     |....| .||.|| .||||  ||.|..||.| 
IMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Spur_PTPRB3.AA Subfamily.R_Anemone_2.PD 2282-2538 40 2e-85 278.0 In-house 2-258 (262) Show / Hide
Range on Protein: 2282-2538
Range on HMM: 2-258/262
Sequence Identity: 40% (105 aa)

FVEEYNSLSNVGRD-KSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMI
. |||. ||.. .   .....   ||..|||| |||..|.| |.||.||. ..|||||||||.| .. |.|||.|.|.|. ..||| ||.| .|..| |.
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TGLVEGGKTKCEHYWPDDDtPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGMQQ--FETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAH-DANLGPITVH
| ..| ||.|...|||... . .||...|..... |......||| ...  ..   . .|. .  ||..||...  .....|... |. ... |||.|||
tqeeergkakvhryWPskg-srsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvh

CSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
|||.||||||||.  |.....    .  .|| .|| ..||||  ||||.|| ||.. ||  
csaGvGrtGvfiavdillerika---ealvdvfqtvkqlreqrnlmvqtkdqyefiydvll

Phosphatase Spur_PTPRB3.AA Subfamily.N_Choan_1.PD 2281-2539 41 3.1e-84 273.9 In-house 1-259 (262) Show / Hide
Range on Protein: 2281-2539
Range on HMM: 1-259/262
Sequence Identity: 41% (108 aa)

GFVEEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMI
||.|||..|...|.|... ||.   | .||||.||  .| | |.... || ...||||||...|... |||||.|||||.|...||.||.|.| ..|.|.
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv

TGLVEGGKTKCEHYWPDDDTPVNYGSVTVTMTHTQEMEQWTVRSFLL-EKGMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANL-GPITVHC
|  .|.|| || .||||... ...| |||......| ...  | | | ... .. | .| |.. | || ||.... ..|| . .  |.. .   |. .||
treieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihC

SAGIGRTGVFIALHKLIKQVETSKpnDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLL
|||.||||..||| .|.|.||...  . .||. .|| .|..|  ||||. || |.....| 
saGvGrtGtyialDrlvkaveeka--ealdvkavvaelrkernlmvqtlvqyefvykavld

Phosphatase Spur_PTPRB3.AA Subfamily.R_Sponge_2.PD 2286-2538 36 4.1e-76 247.3 In-house 5-258 (262) Show / Hide
Range on Protein: 2286-2538
Range on HMM: 5-258/262
Sequence Identity: 36% (95 aa)

YNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDlEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVE
.. ..   . |.....|  | .|||...|||.|.. |.|.  .. ..||||||....|... | |||.|||....|.||| ||.| |..|| |.| |.| 
eeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnlee

GGKTKCEHYWPDD-DTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGM---QQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLG-PITVHCSA
|| ||..|||.  |  |.||...||............| . | |     .. .  |. |  | .|.||..| ...|.|...  |.  . . .|||.||.|
ngkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsd

GIGRTGVFIALHKLIKQVetsKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
.|||| ||||. .....   | .. |||  ... .| .|  .||...|| |||. || 
gvgrtGtfialdsvlerl---kaeeeidvfevlktlrtkriglvqdaaqYvfihdall

Phosphatase Spur_PTPRB3.AA Subfamily.R_Anemone_1.PD 2282-2538 35 4.5e-74 240.8 In-house 2-254 (258) Show / Hide
Range on Protein: 2282-2538
Range on HMM: 2-254/258
Sequence Identity: 35% (91 aa)

FVEEYNSLSnVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMIT
. .|.. |.  .........| | | .|||| .|...|.. | |..|.. ..|||||| |... .  ...||.|.|....|.||| ||...|...| |.|
yaaefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

GLVEGGKTKCEHYWPDddTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGMQQ--FETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLGPITVHCS
.|.|| |.||..||||  .. .||...|........ ....|...|.|  ..   | .|| |  ||. ||..|. .... |..   . |.  |. |||||
nliegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCs

AGIGRTGVFIALHKLIKQVETSKpndYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
|.||||.|.... ...|. ..|    .|.  .| ..||.| .|||| .||.|||. .| 
aGvgRtGaflvidamleqakkek---vvDifnyvkairedrphmvqtkeqyvfihlavl

Phosphatase Spur_PTPRB3.AA Subfamily.RA.PD 2282-2538 36 1.9e-73 238.5 In-house 2-262 (266) Show / Hide
Range on Protein: 2282-2538
Range on HMM: 2-262/266
Sequence Identity: 36% (97 aa)

FVEEYNSLSNVGRD-KSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMI
. ||...|..|    .. ... .  |  |||. .|||.| . |.|. .|  ..|||||| .|.| .  ...||.|||  ..|.||| |..|||.|| |.|
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TGLVEGGKTKCEHYWPDDDTpVNYGSVTVTMTHTQEMEQWTVRSFLLEKG------MQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLG-P
 | | ...||  ||||. . | || ..|.. .....|..||| ||...        ..   .|. |..| .  || ... |..... .   .. . . ||
telkerkeekcaqywpdeGl-vtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhp

ITVHCSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
.||||||.|||| ||.| .....|..   .. .|| ..| |.| || .|||| .|| ||.. || 
ivvhcsaGvGrtGtfivldavlervka---erkldvfeavkrlrlqrpqmvqtleqyefiykvll

Phosphatase Spur_PTPRB3.AA Subfamily.N12.PD 2297-2540 36 1.3e-72 235.6 In-house 23-268 (270) Show / Hide
Range on Protein: 2297-2540
Range on HMM: 23-268/270
Sequence Identity: 36% (89 aa)

STDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWP
||.|..  .| .||||..|||.|.. |.|.  || . |||||||.|.| .. .||||.|||.|. ..||| |..| . . . |.  .|| ||.|||.|||
steagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp

DD-DTPVNYGSVTVTMTHTQEME-QWTVRSFLLEKGMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLGPITVHCSAGIGRTGVFIALHKL
.  ......|...||... . .. ....|.. .|.  .. . .|. .. | ||.||..| ...|.|...   ....  |. ||||||.||||. ||.   
eegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyv

IKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLL
 ..... | .. .||   |...|.||  .||| .|| ....... |
rellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase Spur_PTPRB3.AA Subfamily.RG.PD 2282-2540 32 5.1e-71 230.6 In-house 2-262 (264) Show / Hide
Range on Protein: 2282-2540
Range on HMM: 2-262/264
Sequence Identity: 32% (87 aa)

FVEEYNSLSNVG-RDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMI
. |... ....  .| ....|.   | .|||. ||...... |.|..| . . .|||||.||.| .  ||||..|||... ..||| |..|.....| |.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TGLVEGGKTKCEHYWPDDDTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGMQQFETH----QYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLGPITV
| |.| |. ... |||..|.|.......||......... |||.|.|..  .. |..    || .  | |...|. . ... |..  . |.... |||.|
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivv

HCSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLL
|.||| ||.|..|||  |..|.|.   .. ..| ... ..| .| ..|.|  ||.||.. || |
hdsaGvgragtyialdtllqqlek---eeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase Spur_PTPRB3.AA Subfamily.R_Ecdysozoa.PD 2282-2538 34 5.3e-71 230.3 In-house 2-265 (269) Show / Hide
Range on Protein: 2282-2538
Range on HMM: 2-265/269
Sequence Identity: 34% (94 aa)

FVEEYNSLS-NVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMI
. |||..|  ..  .||| .|    || ||||..| .||.| | |. ..  ..||||||..|.| .  |..||.|.||   ..||| |. | ..|.| |.
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TGLVEGGKTkCEHYWPDDdTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGM-----QQFETHQYAFKGWV-DHDVPNNARPMIEFIRTIDVAHDAN----
. | |  .  |..|||.. . |.||.. |.. ......... |.. . |       .. .  || ..||  |  ||. || ....|. .   .  |    
snlteknrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

-LGPITVHCSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
  .||.|||||| ||.|.|.||  |..|...   .| .|.. ||  .|.||  .|| ..||.|... |.
srsPivvhCsaGvgrsgifvaldlllqqlka---edkvdifetvkkLrsqrnllvqsleqyvflyrala

Phosphatase Spur_PTPRB3.AA Subfamily.N3.PD 2286-2538 36 7.8e-71 229.8 In-house 6-257 (261) Show / Hide
Range on Protein: 2286-2538
Range on HMM: 6-257/261
Sequence Identity: 36% (95 aa)

YNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDleeGQTsDYINANYI----QGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMIT
...|     . ...|.|.. |..|||||.|||.|.| |.|..   ..| |||||||.    .. . .. |||.|||......|||.||.|.|||.| |.|
feelyrkkpglaisaarkpenlaknryrdilpydatrvklke---set-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlt

GLVEGGKTKCEHYWPDDDTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGM--QQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLGPITVHCS
 ||| |..|| .|||. .  ...|...|......| ... .| ..|..    .. . .|  .  | ||.||...  ..||...... ..  |. ||||||
tlverGrvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCs

AGIGRTGVFIALHKLIKQVETSKPNDYIDVcgtVARMREQRFNMVQTVKQYMFIHQCLL
||||||.|.|   .  .|...|   .|.   | .||.|| ..||||.|| |. ...|  
aGigrtGvlilletalalieaaepvypldi---vrtmrdqramlvqtvsqykfvCeail

Phosphatase Spur_PTPRB3.AA Subfamily.N5_RR.PD 2297-2539 35 1.6e-68 222.3 In-house 14-262 (265) Show / Hide
Range on Protein: 2297-2539
Range on HMM: 14-262/265
Sequence Identity: 35% (87 aa)

STDASRLAVNATKNRYRNILPFDETAVHLQ-DLEEGQTSDYINANYIQGLHS-MKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHY
|..  ... ..|||||..||| ... | |. .  | . |.|||||||.| .   | |.| |||.|  ..|||.|....... | |.| ||  ..||..|.
sqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavy

WPDDDTP---VNYGSVTVTMTHTQEMEQWTVRSFLLEKGMQ-QFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAH---DANLGPITVHCSAGIGRTGV
||.       .|| | ...... | ....||...|..  . . . . | .  | ||..|........... .. ...|.|.|. |||||||||||.||| 
fPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGc

FIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLL
.  ..|..    .  .|| ..|...| .|  |||| .|| .||. | |    
fiaisiavrqlre---eivvdvlkivcnlrldrGGmvqtseqyelihralcl

Phosphatase Spur_PTPRB3.AA Subfamily.RK.PD 2282-2538 33 4.2e-68 220.8 In-house 2-263 (267) Show / Hide
Range on Protein: 2282-2538
Range on HMM: 2-263/267
Sequence Identity: 33% (90 aa)

FVEEYNSL---SNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGqTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIA
. ||...|   .  .. .. |.. .  | .|||. .||..| . | |. ...   ||||||..| . .  ...|. |||... |.||| .|.......| 
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MITGL-VEGGKTKCEHYWPDdDTPVNYGSVTVTMTHTQEMEQWTVRSFLLEK---GMQ-QFETHQYAFKGWVDH-DVPNNARPMIEFIRTIDVAHDA-NL
|.| | || |. || .|||. || |.|| . |.. ...  ..  || | .||   |.. . | .|. | || .. |||...| ....|| ..  ..  . 
mlteldvevgrvkClkyWPe-dtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeee

GPITVHCSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
|.| |||.|| ||.|.|||.. ... .|.   .. .||  .|  .|... |||.| .||.|...  |
GrivvhClaGaGrsGtfiaidivlemier---egvvdvfnavktlrnrkvnmveteeqykfvydvil

Phosphatase Spur_PTPRB3.AA Subfamily.N13.PD 2284-2540 37 5.5e-67 217.4 In-house 4-257 (259) Show / Hide
Range on Protein: 2284-2540
Range on HMM: 4-257/259
Sequence Identity: 37% (97 aa)

EEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDleEGQtsdYINANYIQGLH--SMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMIT
||.. | ..   .... .. . | .||||||.||.||| |.|.|  ||    ||||..|.        ||||.|||.|..|.||| ||.||.. |||.| 
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgd--egg---yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt

GLVEGGKTKCEHYWPDDD-TPVNYG-SVTVTMTHTQEMEQWTVRSFLLEKG--MQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDaNLGPITVH
 .|.|| ||. |||.    ..     ..|.. ..|......||.. ...    .  |  .  |  | ||.||..| ....|.. .   .. . ||| |||
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvh

CSAGIGRTGVFIALHKLIKQVETSKpndYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLL
||||||.||.|... ..  .|  |    .||  .| ..||||  .||| .||.|... .| . 
csaGiGrsGvlitidvvlglierdk---efdvkeivrklreqrqgvvqtkdqyifvykailev

Phosphatase Spur_PTPRB3.AA Subfamily.N9.PD 2281-2538 34 6.3e-65 210.8 In-house 1-271 (275) Show / Hide
Range on Protein: 2281-2538
Range on HMM: 1-271/275
Sequence Identity: 34% (94 aa)

GFVEEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMI
| ..|| .. |       .||.| .| .|||| ..| .||| |.|. |.| ..|||||||...| .  | .||.|||.. .|.||| ||.|..  .| |.
GlskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmt

TGLVEGGKTKCEHYWP-DDDTPVNYGSVTVTMTHTQEMEQWTVRSFLLE--KGMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVA-----------
| .|| |. || .||| ....  ..|...|.  .....|...||.. ..  |  .. .   . | .| |. ||..|  ........  .           
trvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

--HDANLGPITVHCSAGIGRTGVFIALHKLIKQVETSkpnDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
   ...  || ||||||||||| ||.|   ....|.    . .||. || ..|.||  ..|| .||.| ....|
skghlsgPPivvhcsaGiGrtGtfitldiclarleev---gtvdvvetvkllrtqrafsiqtpeqyefcylavl

Phosphatase Spur_PTPRB3.AA Subfamily.N_Choan_2.PD 2297-2538 32 1.9e-62 202.3 In-house 12-262 (266) Show / Hide
Range on Protein: 2297-2538
Range on HMM: 12-262/266
Sequence Identity: 32% (82 aa)

STDASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLH-SMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYW
...    | |.. |||..|||  .| | |..||| ... ||||||..| . . |.|||..||.| ....|| |..|.|.|.|.|.|||.| |..||| ||
eeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYW

PDD---DTPVNYGSVTVTMTHTQEMEQWTVRSFLLEKGMQQFETHQYAFKGWVDHDVPNNAR------PMIEFIRTIDVAHD-ANL-GPITVHCSAGIGR
| .    . ...| ..|. .... .| . ..   |||. .. .   . .. | || ||...        ... .|..   ..  .  .|. ||||||.||
paepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgR

TGVFIALHKLIKQVETSKpndYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
||..||. . .. .|..|    .||   ....|..| ..||...|| .... ..
tGtliaiDiavrlLeetk---kvdvlaiieelRkdRmalvqhpeqyellykavv

Phosphatase Spur_PTPRB3.AA Subfamily.RC.PD 2283-2537 29 6.6e-53 171.2 In-house 3-283 (288) Show / Hide
Range on Protein: 2283-2537
Range on HMM: 3-283/288
Sequence Identity: 29% (83 aa)

VEEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHL-------------------QDLEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVN
|...| .|   ..   .|   | .|||| ..||.|   |.|                   .| .  ..|.|||| .|.. .  . |||.|||  ..|.||
eaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvd

DFWEMVFENKSTTIAMITGLVEGGKTKCEHYWpdDDTPVNYGSVTVTMTHTQEMEQWTVRSFLLE--KGMQQFETHQYAFKGWVDHDVPNNARPMIEFI-
|.|.||.| . | |.| | || . || .||  ..    || | | . .|.   ....| . |   |  .  |  |. .  |....|.. . ....|    
dfwrmiferkvkvivmltelkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliq

---------RTIDVAHDANLGPITVHCSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCL
      |. .  ..   .|. |||..| .|||.|||| .|.. .|.   .. .|| . | ..| .|  ||...||..... |    
vvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallalleslea---eekvdvfqvvkklrkarplmvsveeqyillydvl

Phosphatase Spur_PTPRB3.AA Subfamily.N14.PD 2284-2538 30 7.6e-53 170.9 In-house 4-271 (275) Show / Hide
Range on Protein: 2284-2538
Range on HMM: 4-271/275
Sequence Identity: 30% (82 aa)

EEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQDLEEGqTSDYINANYIQGLHS--MKEYIASQGPVPDSVNDFWEMVFENKSTTIAMIT
||. ...   |  .....| .|| |||....||.... |.|.  .|  ...||||  |.   .   ..||..|||.. .|.|||.||.|.. . |.|.| 
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

GLVEGGKTKCEHYWPDD---DTPVNYGSVTVTMTHTQEMEQWTVRSFLLEK--GMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVA---HDANL--
  |.||.|. .|.|..      |..|   ||   ... .. . ... |.     .. . .   .. | ||.||.. .....|.. ..      . .    
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

-----GPITVHCSAGIGRTGVFIALHKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
     |. ||||||.||||| |    ||. .|.   |. ||.  ..||.|.||  .|||. || |... |. 
vkeskPPvlvhCsaGvGrtGvlilsdlliatleh---neeidikkvlarLrkqrmllvqtlaqykfvykvli

Phosphatase Spur_PTPRB3.AA Subfamily.N20.PD 2304-2541 41 4.3e-51 165.4 In-house 24-256 (257) Show / Hide
Range on Protein: 2304-2541
Range on HMM: 24-256/257
Sequence Identity: 41% (99 aa)

AVNATKNRYRNILPFDETAVHLqdleeGQTSDYINANYIQGLHSMKE--YIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPDD-DT
|  |||||.|||.| | | |     |.. |||||.||. .   .|  |||.|||.  ...|||.||.||.|  |||||  .|||  ||||||     |..
psnreknryrdilpydstrvpl-----gkskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkk

PVNYGSVTVTMTHTQEMEQWTVRSFL-LEKGMQ-QFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDAnlGPITVHCSAGIGRTGVFIALHKLIKQV
   . | .   | .. . .| |  .||     .  .|  |  | ||  | .|  .|..||    .| .  ||. |||||||||||||...  ..  .   
plelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshlt--gpmvvhcsagigrtgvflcvdvvfcai

ETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLLM
  |  ...   ||.|||||  |||| .|| | .. .| ..   
vk---ncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl

Phosphatase Spur_PTPRB3.AA Subfamily.RN.PD 2285-2536 33 5e-51 164.9 In-house 5-258 (264) Show / Hide
Range on Protein: 2285-2536
Range on HMM: 5-258/264
Sequence Identity: 33% (87 aa)

EYNSLSNVGRDKSTD-ASRLAVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHS-MKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITG
|...| .   ..||  ...   |..|||....||.|.. |.|..  . ..||||||  |      .  |||.|||..... |||.||.|. .. | ..| 
ewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltr

LVEGGKTKCEHYWPDDDTPVnYGSVTVTMT-HTQEMEQWTVRSFLLeKGMQQFET---HQYAFKGWVDHDVPNNARPMIEFIRTIDVAHDANLGPITVHC
| | | ..|..||||. . | |.   | .       ... |||| | | .|. ||    |. |  | ...|| .|....|| |.. ..     || ||||
leeegvkqckrywpdeGsev-yhiyevhlvsehiwcddylvrsfyl-knlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhc

SAGIGRTGVFIALHKLIKQVEtsKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQC
.| |||||.|..  .....   |    ||.. |.  .|.|| ..|.| .|. |. .. 
sdGaGrtGvyilidlvlerll--kGvkeidiaatlehlrdqrpglvktkdqfefalta

Phosphatase Spur_PTPRB3.AA Subfamily.N23.PD 2319-2538 31 2.7e-50 162.8 In-house 115-346 (350) Show / Hide
Range on Protein: 2319-2538
Range on HMM: 115-346/350
Sequence Identity: 31% (74 aa)

DETAVHLQ-DLEEGQTSDYINANYIQGLHSMK-EYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPDD-DTPVNYGSVTVTMTHTQ
|.. |.||   . ||..||||| |.. | .|  ..||.|||.. ...||| ||.|..| .| |.|  |||.|.||..||| | . ....|..|.. ....
dpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslr

EMEQWTVRSFLLEKGMQ--QFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAH----DA-----NLGPITVHCSAGIGRTGVFIALHKLIKQVEtsKPN
 |.|  | . |..  .    .  .  .. | .. ||.    ...|.  .. |.     .        || .|||||.||||.|  ..  |....  . | 
ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelt--agn

DYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
 |..   | |.|.|| .|||..... .. .  | 
giiniprvvrrlrqqRkymvqkkvilkklyeavl

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_1.PD 2283-2538 31 1e-49 160.7 In-house 3-261 (265) Show / Hide
Range on Protein: 2283-2538
Range on HMM: 3-261/265
Sequence Identity: 31% (83 aa)

VEEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLQdlEEGQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITG
..|...| .  . ....| . | .| ||||...   |...| |.  ||. .|||| |||.      | .| .|.|. ....||| ||. .|  .| |.  
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlck

LVEGGKTKCEHYWPDDDTPVN-YGS----VTV----TMTHT-QEMEQWTVRSFLLEK-GMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVahdaNL
|.| ||.||..|.|  . ... . .    .||    .. .. .. |. .|  . .|  | .. ....| .. | |. ||.    ..|..  . .    . 
liekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrg----sk

GPITVHCSAGIGRTGVFIALHKLIKQVETSKPNDyiDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
||| |||||||||||  .|.. .. ..  .|  .  |.   | ..|||| . .|| .||.|.|. ||
gPivvhCsaGiGrtGtivaieyildkllegkqie--dmeklvkkireqrnysiqtdaqylfvhrvll

Phosphatase Spur_PTPRB3.AA Subfamily.N1.PD 2297-2536 26 2.3e-47 153.1 In-house 19-262 (268) Show / Hide
Range on Protein: 2297-2536
Range on HMM: 19-262/268
Sequence Identity: 26% (65 aa)

STDASRLAVNATKNRYRNILPFDETAVHLQDLEEgqtsDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWP
.| ...|  | ..||||.. |.| . ..|.. .     |||||. ..  .  ..|| .|||.|. .. ||.||.|..| .. |.  .|| ...|| .|||
etreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp

DDDTP--VNYGS--VTVTMTHTQEMEQWTVRSFLLEK--GMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVA--HDANLGPITVHCSAGIGRTGVF
 ..    . . .   .|..  ... ....|| . ||     .  |  .. .  | |  ||.    ...|. ..  .     ..||. .||||||||.| .
qeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtl

IALHKLIKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQC
  . ... ..|  .  . .|.   .  .|..|  ..||  |  |  . 
slvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyia

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_4.PD 2303-2538 27 4.3e-46 148.8 In-house 23-260 (264) Show / Hide
Range on Protein: 2303-2538
Range on HMM: 23-260/264
Sequence Identity: 27% (68 aa)

LAVNATKNRYRNILPFDETAVHLQDLEegQTSDYINANYIQGLhSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPDDDTP-
|. ||||..||  ||| | |.. .     ||| |....      .||..|||......||| ||...| ... |.  |.|.|  ||. |.|...   |..
seknsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekv

VNYGSVTVTMTHTQEM-------EQWTVRSFL--LEKGMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVahDANLGPITVHCSAGIGRTGVFIALH
|.  .|.....|.       .  .| .    ..   ...  . . .. | |.  | .|.|.|......    . . .|| ||||||.|||  .. ..   
vkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGid

KLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
 ..     |  |.|   | ..|. |.. ||.  |..|.  .|.   
yatirire---nseievldivrelramrlkavqshlqflfllvvli

Phosphatase Spur_PTPRB3.AA Subfamily.R_Nematode_2.PD 2298-2538 28 1.3e-43 140.5 In-house 21-257 (261) Show / Hide
Range on Protein: 2298-2538
Range on HMM: 21-257/261
Sequence Identity: 28% (70 aa)

TDASRLAVNATKNRYRNILPFDETAVHLQdlEEGQTSDyINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPD
. |   ... |.|| ..   .||||.     .|. .. | ||...     | .||.|||. . ..||| ||  .|  .| |..  ||  |.|||.|.| .
vtesaaylpkdkhRypdvPCkpetavevi--vdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpl

D-DTPVNYGSVTVTMTHTQEMEQ--WTVRSFLLEKGMQQFETH---QYAFKGWVDHDVPNNARPMIEFIrtiDVAHDaNLGPITVHCSAGIGRTGVFIAL
    .. | ........... .   ..|..  |.. ..|.|.    | .. | |..||.. | .   ..... .  || ||||||||||. ||. . | .
etsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLl---elvkk-sekPivvhCsaGiGRtmafigt

HKLIKQVETskpNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
.||.   .. | .  ... .||.| . .|| .|.....  .|     
eylarevea---dptieltealkelrehRwkgiqtesqlywltlgal

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_6.PD 2284-2538 27 9e-42 134.7 In-house 4-249 (253) Show / Hide
Range on Protein: 2284-2538
Range on HMM: 4-249/253
Sequence Identity: 27% (71 aa)

EEYNSLSNVGRDKStdASRLAVNATKNRYRNILPFDETAVHLQDLEEgqtsDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGL
||.. .| . ...  |. .  . ..|||.||  .| . ..|.| |.     || ||...     . .| .|.|. .....||.|..   .. | |. .||
keykdspneasese--ataflkfkdrnrytniqCcdagrlkladded----fyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcel

VEGGKTKCEHYWPDD--DTPVNYGSVTVTMTHTQEMEQWTVRSFL--LEKGMQQFETHQYAFKGWVDHDVPNNARPMIEFIrtiDVAHDaNLGPITVHCS
| || |. .| .|   |. .   . ||.    ..... .||| .    .| ..   . . ..| || ||..    . ..    | .. .  || ||||||
vekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrll---svvkk-dkkPivvhCs

AGIGRTGVFIALHKLIKQVetsKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
.|||| .. .  ... .   .  |...|   ....||.||  |||. ||.. ..|.|  
aGvGrtGtlaliliileal---rlpdfqgvkdllvklreerfravqtevqylyalrcvl

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_5.PD 2285-2540 23 6.7e-37 118.5 In-house 5-256 (258) Show / Hide
Range on Protein: 2285-2540
Range on HMM: 5-256/258
Sequence Identity: 23% (61 aa)

EYNSLSNVGRDKStDASRLAVNATKNRYRNILPFDETAVhlqDLEEGQtSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLV
|.. |...  .|  . .    | .|||. ..   ||| |    |.... ..||||..|.  .. |..|  | |.||...|||.||...| |.. ....  
efeklaslkpnke-tckafeknlkknrskdvkilDetrV---kltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvede

EGGKTKCEHYWPDDDTPVNYGSVTVT---MTHTQEM-EQWTVRSFLLEKGMQqFETHQYAFKGWVDHDVPNNARPMIEfiRTIDVAHDAN---LGPITVH
|  .|... .    ..  |.| ....   ... ... ...||  .  ... .   .. | .. |.. ||..  ..|.  |.|   .. .     |. |..
elketavsffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvv

CSAGIGRTGVFIALHKLIKQVETSKPNDyidVCGTVARMREQRFNMVQTVKQYMFIHQCLLLL
..|.||.| |..|   |.|... |  .   .. ..  .|.|| ..|....||.......|   
sdlGlgRagtflllsvaieqlnngkepn---ideilkkirsqRpgavesliqyasvyaavldy

Phosphatase Spur_PTPRB3.AA PTPc_motif 2435-2539 38 1.2e-36 128.95 SMART 1-92 (92) Show / Hide
Range on Protein: 2435-2539
Range on HMM: 1-92/92
Sequence Identity: 38% (42 aa)

ETHQYAFKGWVDH-----DVPNNARPMIEFIRTIDVAHDANLGPITVHCSAGIGRTGVFIALHKLIKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQ
. |.| . .| ||      ||    ...|||| .         || ||||||.||||.|.|.  .. |         .|...|| .||.|| .||||  |
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQTEEQ

YMFIHQCLLL
|.|...|.| 
YIFCYRCILE

Phosphatase Spur_PTPRB3.AA Subfamily.R_Nematode_3.PD 2295-2540 21 1.3e-33 107.9 In-house 15-265 (267) Show / Hide
Range on Protein: 2295-2540
Range on HMM: 15-265/267
Sequence Identity: 21% (56 aa)

DKSTDASrlaVNATKNRYRNILPFDETAVHLQDLEEGQTSDYINANYIQGLHSMkEYIASQGPV--------PDSVNDFWEMVFENKSTTIAMITGLVE-
..|. |    . ...|. ... . .| | |..     ..|.|.||...  ... . | .|.|          . .. || |. ..|.. ..|.   ||  
knatsls---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpngl-klIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfvee

--GGKTKCEHYWPDD-DTPVNYGSVTV-TMTHTQEME-QWTVRSFLLEK-GMQQFETHQYAFKGWVDHDVPNNARPMIEFIRTIDVAHdanlGPITVHCS
 ... || .|.|.. |. .. . |.| ... ..|.. .   |.. ..    ..|  . ...||| .. .|.......| |. .         |. ||||.
dgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCs

AGIGRTGVFIALHKLIKQVETSKPndYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLL
||.|.... | .  .  . .||    .|.   .  .|.|| . .|| ....|.  ..| | 
dGisRsatlaaielgyqliikskg--kldllslikelrkqRagaiqtelelafvilgilkl

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_egg.PD 2281-2541 22 2.1e-27 87.6 In-house 1-256 (257) Show / Hide
Range on Protein: 2281-2541
Range on HMM: 1-256/257
Sequence Identity: 22% (60 aa)

GFVEEYNSLSNVGRDKSTDASRLAVNATKNRYRNILPFDETAVHLqDLEEGQT-SDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAM
....... | ..  ..|   .  . . .| | . .   . . |.| .|..||   |.| ||...|   . |.| .| |...|.||| |||..|   | |.
elerrfeilersvdeislttaasdnylekarskrvhckessrvkl-elrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivm

ITGLVEGgkTKCEHYWPDD-DTPVNY--GSVTVTMTHTQEMEQ--WTVRSFLLeKGMQQFETHQYAFKGwvdhDVpNNARPMIEFIRTIDVAHDANlGPI
|  .|    .||.|||   . .. .  ||. ..  . ..  .  ..|  . |  | ..| .   ..|    || |..  .   .| .  . ..   |. |
ltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl-vGgddeelflehwqg----dv-nylsdvysplrvlrklrnls-kpv

TVHCSAGIGRTGVFIALHKLIKQVETSkPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLLM
..  |. ......|.   . ..    |     |  .|.| .|   |..| .|.|... .|  .    
vvqdilGvskaatlvaieiallsllrG-pitkslvlravvflrlrrrlsvesvllylfvyrlvlffi

Phosphatase Spur_PTPRB3.AA Subfamily.N_Fungi_PTP1.PD 2306-2416 33 2.6e-24 77.2 In-house 45-165 (343) Show / Hide
Range on Protein: 2306-2416
Range on HMM: 45-165/343
Sequence Identity: 33% (41 aa)

NATKNRYRNILPFDETAVHLQ-D-------LEEGQTSDYINANYIQGL------HSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKC
.||||.||||.. . |.|.             .|.|||||||..         .   ||| |.|.|  |.||......||. | ..| .|| .  ||..|
lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekc

EHYWPDddtpVNYGSVTVTMTHTQE
|..     .|  .|| .. ..|   
yrYWqe----gsydditvklaskwe

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_eak.PD 2302-2452 27 5.5e-20 63.2 In-house 22-172 (281) Show / Hide
Range on Protein: 2302-2452
Range on HMM: 22-172/281
Sequence Identity: 27% (40 aa)

RLAVNATKNRYRNILPFDETAVHLQDLEEgQTSDYINANYIQGLHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPDDDTP
.   .  .||  .|.|.|   |.|      .   ||||  ..  .  ..|| .  .  | |  ||.||.|.|| .| ..|| .  | . |.||.   ..|
arleavnrnrvvkivpqdrylvrltssql-nrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktev

VNYGSVTVTMTHT-QEMEQWTVRSFLLEKGMQQFETHQYAFKGWVDHDVPNN
| . |.  .   . ..  .| . |.|| .  . . | . || . ..|     
lkyGildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpky

Phosphatase Spur_PTPRB3.AA Subfamily.N_Fungi_PTP1.PD 2402-2541 25 4.9e-19 59.9 In-house 198-342 (343) Show / Hide
Range on Protein: 2402-2541
Range on HMM: 198-342/343
Sequence Identity: 25% (40 aa)

VNYGSVTVTMTHTQemeqwtvrsfllekgmqQFETHQYAFKGWVDHDVPNNARPMIEFIR----TIDV------AHDANLGPITVHCSAGIGRTGVFIAL
|   ..||.  ..                  .| .|  .| | |  . .| . ... .      ||        ..|.. || ||||||.||||....| 
nnndltpvtaavse-----------------pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtl

HKLIKQVE-----------TSKPNDYIDV-CGTVARMREQRFNMVQTVKQYMFIHQCLLLLM
 |....|             ...   |.   .| ..|.|| .|||...|..||...|| .  
DsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfyf

Phosphatase Spur_PTPRB3.AA Subfamily.PTPDC1.PD 2434-2537 28 5.6e-10 30.5 In-house 133-224 (229) Show / Hide
Range on Protein: 2434-2537
Range on HMM: 133-224/229
Sequence Identity: 28% (28 aa)

FETHQYAFkGWVDHDVPNNARpMIEFIRTIDVAHdaNLGPITVHCSAGIGRTGVFIALHKLIKQVETskPNDyidvcgTVARMREQRFNMVQTVKQYMFI
.   | | |. |..|.   | ... .. .| |   . | |.||| || ||||| || . . ..  |  ...       .  .|..|. .|| .|  ....
qgiyfynf-glkDygvasler-iLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvyakrlt--aee------aiklvrskrpksiqtreqvelv

HQCL
    
eeFa

Phosphatase Spur_PTPRB3.AA Family.DSP.PD 2370-2491 17 3.7e-09 27.8 In-house 129-205 (387) Show / Hide
Range on Protein: 2370-2491
Range on HMM: 129-205/387
Sequence Identity: 17% (22 aa)

FENKSTTIAMITglveggktkcehywpdddtpvnygsvtvtmthtqeM------EqwtvrsfllekgMQQFEthqYAFKGWVDHDVPNNARpMieFIRTI
.|.. | |  .|                                          .             ....   |   .. || .|. .. .|.. ||.
kelgvtkivnlt-----------------------------------ddkpqftk------------elgik---ylripidDhnapplen-l--fekai

DVAHDAN--LGPITVHCSAGIGRTGVFIAL
 ...|   | . ||| ||.||.|. |.   
dfieegndskgvVlVHCkaGkgRsgtliia

Phosphatase Spur_PTPRB3.AA Subfamily.DSP23.PD 2450-2533 25 1.2e-07 23.3 In-house 46-120 (128) Show / Hide
Range on Protein: 2450-2533
Range on HMM: 46-120/128
Sequence Identity: 25% (21 aa)

PNNARPMIEFIRTIDVAHDANlGPITVHCSAGIGRTGVFIALHkLIKQVETSKpNDyidvcgTVARMREQRFNMVQTVKQYMFI
|     . ...| ...|.. . ....|||  |.|||| ..| . |.|. . .  .|      ..| .|..|   ..||.|   .
PPaleqvarlvriveeaekke-eavgvhcalGlGrtGtllacy-lvkeeglaa-dd------aiaevrkrrkGsietveqekav

Phosphatase Spur_PTPRB3.AA Subfamily.CDC14.PD 2457-2504 36 8.7e-07 20.3 In-house 188-230 (258) Show / Hide
Range on Protein: 2457-2504
Range on HMM: 188-230/258
Sequence Identity: 36% (17 aa)

IEFIRTIDVAhdanLGPITVHCSAGIGRTGVFIALHkLIKQVETSKPN
.|.. .. |     | | ||| ||.||||..|. . |||. . . .. 
kkfleiteka----eGaiavhCkaGLGrtgtligcy-likhyrftaae

Phosphatase Spur_PTPRB3.AA Subfamily.N_Nematode_eak.PD 2473-2538 28 9.6e-06 16.5 In-house 214-277 (281) Show / Hide
Range on Protein: 2473-2538
Range on HMM: 214-277/281
Sequence Identity: 28% (19 aa)

PItVHCSAGIGRTGVFIALHKLIKQVETSKPNDYiDVCGTVARMREQRFNMVQTVKQYMFIHQCLL
|| . .. |  |.|||. .  ||. ..  | | |  |   . .....|   | . .|. ||.. .|
pi-iqsarGsaraGvfvvidllirlidnkkknly-svedlilkvkskrihsvlvalqhsfiyeivl

Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPRB3.AA Protein None 2542 None Fasta, JSON
Spur_PTPRB3.NA RNA None 7626 None Fasta, JSON
Spur_PTPRB3.AA.PD_2281-2542 Protein Phosphatase Domain None 262 None Fasta, JSON