• Phosphatome.Net

Gene Spur_PTPRB1

Spur_PTPRB1
Species: S.purpuratus
Alias: Spur_PTPRB1, Spur_hmm102386, hmm514705
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of Spur_PTPRB1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Spur_PTPRB1.AA PTPc 109-345 26 3.1e-50 174.14 SMART 1-308 (308) Show / Hide 
Range on Protein: 109-345
Range on HMM: 1-308/308
Sequence Identity: 26% (88 aa)

SLRGEGAMTVQARPAE---------RSARVLRAMPV-----R--GMFNATSDMSTGYGLTIQAKYEHSRVKLMALKGK----SETDYINANYIPGFNSPR
... |  .  ...|           .     .   .     |  .               | . |.|.||||  ..|.    . .||||||||.|...|.
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKC--------------DIPC-YDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPK

EYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEG--------------------------------GKNKMK-------------------------
.||..|||||.| .| |||.|. |..||||... .|.                                 ..|..                         
RYICTQGPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSE

-REVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIR-----------------KKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEM
 |.| ....|.|||||||| ....|||.. ||.. .                 ..|   |.|||||||.|||||..|.| . |..|.   ||....|..|
TRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMM

RMHRNYLVQTEVDSSRAGSHSMNYGILLEIAE
|..|...||||        ..  | ..|| ..
RNQRPGMVQTEEQ------YIFCYRCILEYIK
Phosphatase Spur_PTPRB1.AA Subfamily.RB.PD 230-341 62 1.8e-52 169.7 In-house 152-257 (261) Show / Hide 
Range on Protein: 230-341
Range on HMM: 152-257/261
Sequence Identity: 62% (69 aa)

MKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEVDssr
||.|.|..|||||||||||.||..||||..|||.|.||.. ||.|||||||||||||.||||||.|..|.||.|||.|||.|.|..||.|||||..    
ekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekq---

agsHSMNYGILL
  . . . .|| 
---yifihecll
Phosphatase Spur_PTPRB1.AA Subfamily.RB.PD 123-231 55 2.8e-45 146.1 In-house 6-112 (261) Show / Hide 
Range on Protein: 123-231
Range on HMM: 6-112/261
Sequence Identity: 55% (61 aa)

AERSARVLRAMPVRGMFNATSDMSTGYGLTiqAKYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQT
.|. ..| ....|. . .|...... .  .  ..|.||||||.||| .|.|||||||||||.||||||||.|||||||..|.|||.|||||.||||.||.
yeelkkvgkdqavkaaeeavnraknrftni--lpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltql

VEGGKNKMK
||.||.|..
vEkgkekce
Phosphatase Spur_PTPRB1.AA Y_phosphatase 231-324 45 9.5e-39 137.43 Pfam 136-231 (243) Show / Hide 
Range on Protein: 231-324
Range on HMM: 136-231/243
Sequence Identity: 45% (46 aa)

KREVIQLQFTSWPDHGVPEQ-TKPMLDFVKNVREHIRKKCVIK------PVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQT
.|.| ....|.||||||||  .|.||||.. ||.. .     .      |.|||||||.|||||..|.| . |.||... ||....|..|| .|...|||
TRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-----NPDHGCPPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQT

E
|
E
Phosphatase Spur_PTPRB1.AA Subfamily.N_Choan_1.PD 230-325 56 5.3e-36 115.7 In-house 153-248 (262) Show / Hide 
Range on Protein: 230-325
Range on HMM: 153-248/262
Sequence Identity: 56% (54 aa)

MKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKKCViKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDF-VDVCGVVCEMRMHRNYLVQTEV
.||| ||..|.|||||||..|| .|.| |.|..  .||    |.|.|||||||||||||||||| ...|..   .||. || |.|.||..||| |  
etreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlv
Phosphatase Spur_PTPRB1.AA Y_phosphatase 157-229 49 8e-34 120.09 Pfam 13-87 (243) Show / Hide 
Range on Protein: 157-229
Range on HMM: 13-87/243
Sequence Identity: 49% (37 aa)

YEHSRVKLMALKGKSETDYINANYIPG-FNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGK-NK
|.|.||||  . |.  .||||||||.| ...|..||..|||.|.| .| |||.|. |.|.|||... .|.|. .|
YDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEK
Phosphatase Spur_PTPRB1.AA Subfamily.R_Anemone_2.PD 156-232 55 1e-32 105.1 In-house 38-114 (262) Show / Hide 
Range on Protein: 156-232
Range on HMM: 38-114/262
Sequence Identity: 55% (42 aa)

KYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMKR
|...||||  |.|. ..||||||||.|... ..|||.|.||||| .|.|||.||..|..|||.||..| || |..| 
aydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhr
Phosphatase Spur_PTPRB1.AA PTPc_motif 233-336 37 1.9e-32 115.01 SMART 1-92 (92) Show / Hide 
Range on Protein: 233-336
Range on HMM: 1-92/92
Sequence Identity: 37% (41 aa)

EVIQLQFTSWPDH-----GVPEQTKPMLDFVKNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEVDS
.| ....|.||||     ||||  ...|.|.. ||.         |.|||||||.|||||..|.| . |.      ||....|.|||..|. .||||   
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY

SRAGSHSMN
       ..
IFCYRCILE
Phosphatase Spur_PTPRB1.AA Subfamily.R_Anemone_2.PD 231-324 46 6e-31 99.3 In-house 155-247 (262) Show / Hide 
Range on Protein: 231-324
Range on HMM: 155-247/262
Sequence Identity: 46% (43 aa)

KREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREhIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
.|.| | ..|||||.||||..  .||.|..|.. . ...  .|.||||||||||||..||.| | ......  ||| ..| ..|.|| .|||. 
erqvrqfhytsWpdegvpesgaslldlvrqvek-aqqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtk
Phosphatase Spur_PTPRB1.AA Subfamily.RG.PD 156-229 54 5.7e-30 95.9 In-house 38-111 (264) Show / Hide 
Range on Protein: 156-229
Range on HMM: 38-111/264
Sequence Identity: 54% (40 aa)

KYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNK
.|.|||||  | || ..|||||.|| |..  .|||. ||||.||..| ||||||....||||.|. .| |... 
aversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrd
Phosphatase Spur_PTPRB1.AA Subfamily.N5_RR.PD 229-324 40 1.9e-29 94.2 In-house 154-250 (265) Show / Hide 
Range on Protein: 229-324
Range on HMM: 154-250/265
Sequence Identity: 40% (38 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKK-CVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
...|.|.   .|.|||| .|......||.|..|.|  ...   . |||||||||.|||| .|| .   ...... .||| ..||..|..|.|||.  
rversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqts
Phosphatase Spur_PTPRB1.AA Subfamily.R_Anemone_1.PD 229-325 38 2.8e-29 93.9 In-house 150-244 (258) Show / Hide 
Range on Protein: 229-325
Range on HMM: 150-244/258
Sequence Identity: 38% (37 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHirKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEV
. .|||.|..||.|||.|||.... .|.....|...  ...  .||||||||||||||.....| . ...  .  ||.  .|  .| .| ..|||. 
teerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtke
Phosphatase Spur_PTPRB1.AA Subfamily.RA.PD 225-325 43 3e-29 93.5 In-house 153-252 (266) Show / Hide 
Range on Protein: 225-325
Range on HMM: 153-252/266
Sequence Identity: 43% (42 aa)

GGKNKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHiRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
..| .| | |. |||||. ||| ..| ||...|.|..  ...   .|.|||||||||||||.|.|| . . .. .. .|| ..| ..|. |.|||.    
atrekksrlvrqfhftswpevGvpaegkGmlkllkkvkkl-qqqsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtl

V
 
e
Phosphatase Spur_PTPRB1.AA Subfamily.R_Sponge_2.PD 156-230 49 6.9e-29 92.4 In-house 36-109 (262) Show / Hide 
Range on Protein: 156-230
Range on HMM: 36-109/262
Sequence Identity: 49% (36 aa)

KYEHSRVKLMAlKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKM
|..|||.| . .|....|||||... |....  ||| ||||.|| .|.|||.|| |...|||.|...| ||.|  
pydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekc
Phosphatase Spur_PTPRB1.AA Subfamily.N_Choan_1.PD 156-231 46 8.8e-29 92.0 In-house 37-112 (262) Show / Hide 
Range on Protein: 156-231
Range on HMM: 37-112/262
Sequence Identity: 46% (34 aa)

KYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
|...|||.   . ...|||||||..||.....||||.|||.|.. ...|.|.||.| ..|||.|. .|.|| |   
ayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkCh
Phosphatase Spur_PTPRB1.AA Subfamily.N12.PD 228-324 44 2.4e-28 90.3 In-house 158-255 (270) Show / Hide 
Range on Protein: 228-324
Range on HMM: 158-255/270
Sequence Identity: 44% (44 aa)

NKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKKcvIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDF---VDVCGVVCEMRMHRNYLVQTE
.| .|.| |...|.|||||||...|..|.....|||. ...   .|.||||||||||||| ||.|   . ....     .||  .| |.| .|. ||||.
qkesrkvyqfhytaWPDhgvPssaksllelielvrelqese--daPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtk
Phosphatase Spur_PTPRB1.AA Subfamily.N3.PD 229-324 43 2.7e-28 90.2 In-house 153-246 (261) Show / Hide 
Range on Protein: 229-324
Range on HMM: 153-246/261
Sequence Identity: 43% (42 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHirKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
| .|...|||...|||||||.... .|.||..||.   ...  .|||||||||.|||| .|.|.   . .| .. | .  .| .||  |  ||||.
keerkilqlqylaWpdhgvPddsadflefvervrkl--rsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtv
Phosphatase Spur_PTPRB1.AA Subfamily.N9.PD 155-231 45 5.4e-28 89.5 In-house 36-112 (275) Show / Hide 
Range on Protein: 155-231
Range on HMM: 36-112/275
Sequence Identity: 45% (34 aa)

AKYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
|...||||  |......||||||.. |.. .. .|| ||||..|..| |||.||..  .|||.|..|| |. | .  
lcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcg
Phosphatase Spur_PTPRB1.AA Subfamily.R_Ecdysozoa.PD 230-323 41 1e-27 88.3 In-house 156-253 (269) Show / Hide 
Range on Protein: 230-323
Range on HMM: 156-253/269
Sequence Identity: 41% (40 aa)

MKREVIQLQFTSWP-DHGVPEQTKPMLDFVKNVREHIRKK---CVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQT
.|.|.| ..|.|. |  |||... .|.....|||. ...       |.||||||||||.|...||| | |... .| ||.. .|...| .|| |||  
dsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqs
Phosphatase Spur_PTPRB1.AA Subfamily.RG.PD 227-325 45 1.1e-26 85.2 In-house 154-250 (264) Show / Hide 
Range on Protein: 227-325
Range on HMM: 154-250/264
Sequence Identity: 45% (45 aa)

KNKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVreHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEV
... .|.| |...|.|||.|.||.| ..| |||.      .|    |.|||.||||||.||||||| |.|..|... |.| .|.  .|..|..||.|| 
dkekervvrqyhytkWPdmgsPestlfvlifvkke--eaankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteE
Phosphatase Spur_PTPRB1.AA Subfamily.N9.PD 225-324 38 1.9e-26 84.5 In-house 150-260 (275) Show / Hide 
Range on Protein: 225-324
Range on HMM: 150-260/275
Sequence Identity: 38% (42 aa)

GGKNKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREH-----------IRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEM
|.. .|.|.  ||.||||.|||.... .||....|||.            . ..   |.|||||||.|||||.|.||   ...|. . |||..|  .|  
nvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkll

RMHRNYLVQTE
| . .||.   
rtqrafsiqtp
Phosphatase Spur_PTPRB1.AA Subfamily.N6.PD 228-325 39 1.9e-26 84.4 In-house 181-281 (295) Show / Hide 
Range on Protein: 228-325
Range on HMM: 181-281/295
Sequence Identity: 39% (39 aa)

NKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDF---VDVCGVVCEMRMHRNYLVQTE
.| .||..|..|..|||||||.... .|.|...|... ..     |.|||||||.|||||.| .| ... .| . .   .|.  .. ..|..||||||  
dkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqte

V
 
a
Phosphatase Spur_PTPRB1.AA Subfamily.R_Sponge_2.PD 229-325 37 2.3e-26 84.2 In-house 153-248 (262) Show / Hide 
Range on Protein: 229-325
Range on HMM: 153-248/262
Sequence Identity: 37% (36 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHiRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEV
. ...| | .|..||.|.||... ..|...|.|... .||   |...|.||.|||||||.|||| . .... .. .||  |. ..|..|..|||...
egeadvtqfhfvaWpehevPkdatsllelikrvlra-qkksgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaa
Phosphatase Spur_PTPRB1.AA Subfamily.RA.PD 156-229 49 2.7e-26 83.8 In-house 38-111 (266) Show / Hide 
Range on Protein: 156-229
Range on HMM: 38-111/266
Sequence Identity: 49% (36 aa)

KYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNK
|..||| |  ..|. |.||||| .| |..   ..||.|||. || .|.||||||.||. |||.|.  | ...| 
pydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeek
Phosphatase Spur_PTPRB1.AA Subfamily.N13.PD 231-324 40 5.7e-26 82.9 In-house 154-244 (259) Show / Hide 
Range on Protein: 231-324
Range on HMM: 154-244/259
Sequence Identity: 40% (38 aa)

KREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREhIRKkcVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
||| .|.|..||||||| ...... ||..||. ...     |.|||||||.||.|..|..| . . .| .  .||  .| ..|  |. .|||. 
srevahlnfvkwPdhgvPssaaelvqfvaevrl-lqt--dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtk
Phosphatase Spur_PTPRB1.AA Subfamily.N12.PD 157-232 52 7.3e-25 78.9 In-house 44-119 (270) Show / Hide 
Range on Protein: 157-232
Range on HMM: 44-119/270
Sequence Identity: 52% (40 aa)

YEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMKR
|..|||.|   ... . ||||||.| | ... ||||.|||||.| .| |||||||. .|.||. . || ||.| .|
ydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
Phosphatase Spur_PTPRB1.AA Subfamily.RC.PD 227-324 35 1.3e-24 78.3 In-house 168-273 (288) Show / Hide 
Range on Protein: 227-324
Range on HMM: 168-273/288
Sequence Identity: 35% (38 aa)

KNKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIR--------KKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRN
|.|  ||| |.|.|||.....||. | .|.... |....         |.    |..|||..|..|||..|||. | . .| .. ||| .|| ..|  | 
krkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarp

YLVQTE
 .|..|
lmvsve
Phosphatase Spur_PTPRB1.AA Subfamily.N_Choan_2.PD 230-325 37 1.4e-24 78.0 In-house 151-252 (266) Show / Hide 
Range on Protein: 230-325
Range on HMM: 151-252/266
Sequence Identity: 37% (37 aa)

MKREVIQLQFTSWPDHGVPEQTK------PMLDFVKNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQT
.|..   ....|||||||...        .|. ...||.. ..    .|..|||||||||||| ||.|  .. .| .  |||  ..|.| .|  |||. .
etrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqh

EV
  
pe
Phosphatase Spur_PTPRB1.AA Subfamily.N_Choan_2.PD 159-231 50 1.5e-24 77.9 In-house 35-108 (266) Show / Hide 
Range on Protein: 159-231
Range on HMM: 35-108/266
Sequence Identity: 50% (37 aa)

HSRVKLMALKGKSETDYINANYIPGFN-SPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
..||.|  |. .|.| ||||||..||. ....||| .|||| |... ||||||.|.| |||.|. .| |..| .
atRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCe
Phosphatase Spur_PTPRB1.AA Subfamily.R_Anemone_1.PD 156-231 46 1.6e-24 78.3 In-house 36-111 (258) Show / Hide 
Range on Protein: 156-231
Range on HMM: 36-111/258
Sequence Identity: 46% (35 aa)

KYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
..|||| | .|....|.||||| |. ...  |..||.|.||.||..| |||.|..|...|||.|. .|| |.|.. 
aldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkch
Phosphatase Spur_PTPRB1.AA Subfamily.R_Ecdysozoa.PD 156-227 40 4e-24 76.5 In-house 38-109 (269) Show / Hide 
Range on Protein: 156-227
Range on HMM: 38-109/269
Sequence Identity: 40% (29 aa)

KYEHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGK
... ||||  ..|| ..|||||..| |..  ...|| |.|. .| .|.||||.|...|.|||...  |  . 
afDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknr
Phosphatase Spur_PTPRB1.AA Subfamily.N3.PD 156-230 51 2.1e-23 74.2 In-house 37-111 (261) Show / Hide 
Range on Protein: 156-230
Range on HMM: 37-111/261
Sequence Identity: 51% (40 aa)

KYEHSRVKLMalkgKSETDYINANYI----PGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKM
|.. ||||.    .||||||||||.    |...    |||.||||..|..|.|.|.||.|||.|||.|..|| |. |  
pydatrvklk----esetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkC
Phosphatase Spur_PTPRB1.AA Subfamily.N13.PD 157-232 47 5e-23 73.2 In-house 38-110 (259) Show / Hide 
Range on Protein: 157-232
Range on HMM: 38-110/259
Sequence Identity: 47% (37 aa)

YEHSRVKLMALKGksetdYINANYIP--GFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMKR
|...|||| .  |     ||||..|     .   ||||||||||||..|.|.|.||.|...|.|.|. .|.|| | .|
ydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchr
Phosphatase Spur_PTPRB1.AA Subfamily.RK.PD 156-227 40 6.9e-23 72.5 In-house 40-111 (267) Show / Hide 
Range on Protein: 156-227
Range on HMM: 40-111/267
Sequence Identity: 40% (29 aa)

KYEHSRVKLMALKGKsETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQT-VEGGK
|..|.|.|....|  ..|||||..| ... |...|. ||||.||..|.||........ |||.|.  || |. 
aydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgr
Phosphatase Spur_PTPRB1.AA Subfamily.N14.PD 230-323 44 7.2e-23 72.5 In-house 158-259 (275) Show / Hide 
Range on Protein: 230-323
Range on HMM: 158-259/275
Sequence Identity: 44% (44 aa)

MKREVIQLQFTSWPDHGVPEQTKPMLDFVK---NVREHIRKKC-----VIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLV
.|.|. ||.| ||||||||  |..|.|..    ||..  ..      .  ||.|||||||||||  |  | |.. .| |. .|.  |.  .|| .|||| 
eertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllv

QT
  
qt
Phosphatase Spur_PTPRB1.AA Subfamily.RK.PD 229-324 35 7.4e-23 72.4 In-house 157-252 (267) Show / Hide 
Range on Protein: 229-324
Range on HMM: 157-252/267
Sequence Identity: 35% (34 aa)

KMKREVIQLQFTSWPDH-GVPEQTKPMLDFVKNVREHIRKkCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
. .||| |.||..||.. .||.. . .|.....| ..  .     ..||||.|| ||.||.||.| . . .| .. |||  .| ..| ..  .|.||
eeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-eeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmvete
Phosphatase Spur_PTPRB1.AA Subfamily.RC.PD 168-229 46 2.1e-22 71.0 In-house 68-129 (288) Show / Hide 
Range on Protein: 168-229
Range on HMM: 68-129/288
Sequence Identity: 46% (29 aa)

KGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNK
...  ..|||| .| ..  |. ||| |||| || .|.||||.|.| ..|||.|.  || ..|
dseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrek
Phosphatase Spur_PTPRB1.AA Subfamily.N23.PD 228-325 32 5.4e-22 69.6 In-house 231-336 (350) Show / Hide 
Range on Protein: 228-325
Range on HMM: 231-336/350
Sequence Identity: 32% (34 aa)

NKMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHI--RKKCVI-----KPVVVHCSAGVGRTGTYIALDR-LTQHMEDNDFVDVCGVVCEMRMHRNY
...|.| .|..|.|...|||.  . .|.|...|...   ..|. .     ||...|||||||||||.  .   . .  ..|  ...  || ..|  | | 
vstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRky

LVQTEV
||..| 
mvqkkv
Phosphatase Spur_PTPRB1.AA Subfamily.N5_RR.PD 158-230 44 1.9e-21 67.9 In-house 36-110 (265) Show / Hide 
Range on Protein: 158-230
Range on HMM: 36-110/265
Sequence Identity: 44% (33 aa)

EHSRVKLMALKGKSE-TDYINANYIPGFNS-PREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKM
|.||| | . ....| ..||||||| |..   . |.| |||||.| .|.||||.......|||.|.  |  ..| 
ensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkc
Phosphatase Spur_PTPRB1.AA Subfamily.RN.PD 229-324 36 5.5e-21 66.3 In-house 155-249 (264) Show / Hide 
Range on Protein: 229-324
Range on HMM: 155-249/264
Sequence Identity: 36% (35 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKKCVikPVVVHCSAGVGRTGTYIALDRLTQHMED-NDFVDVCGVVCEMRMHRNYLVQTE
.  | | |. | |||..||| ..|..|.| . |    | ..   |.|||||.|.||||.||..| . ...      .|..  .  .|  |. ||.|.
setrtvtqfhflswpeegvPasaksllefrrkvnksyrGrsc--pivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktk
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_1.PD 231-325 37 7.1e-21 66.0 In-house 162-251 (265) Show / Hide 
Range on Protein: 231-325
Range on HMM: 162-251/265
Sequence Identity: 37% (36 aa)

KREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHirKkcviKPVVVHCSAGVGRTGTYIALDRLTQHMEDN-DFVDVCGVVCEMRMHRNYLVQTEV
.|.| ..|.| |||.|||.    .|.....||..  |    .|.|||||||.||||| .|.. ..... ..    |.  .| ..| .||| .||..
trkvthyqWtdWPdrGvPpadlaalelleavrgs--k----gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtda
Phosphatase Spur_PTPRB1.AA Subfamily.N6.PD 157-231 41 8.8e-21 65.8 In-house 52-140 (295) Show / Hide 
Range on Protein: 157-231
Range on HMM: 52-140/295
Sequence Identity: 41% (36 aa)

YEHSRVKLMAL-KGKSETDYINANYI----------PGFNSP---REYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
..|.||.|    .  . .||||||||            ..|    ..||| ||.|..| .| |||.|...|..|||.|. || ||||  
fDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCa
Phosphatase Spur_PTPRB1.AA Subfamily.N14.PD 157-230 44 1.2e-20 65.2 In-house 38-112 (275) Show / Hide 
Range on Protein: 157-230
Range on HMM: 38-112/275
Sequence Identity: 44% (33 aa)

YEHSRVKLMALKGKsETDYINANYIPGF--NSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKM
||..||.|.. | . .|.||||  |      . |.||..||||..| .|.|.|.||.. ..|||.|.. |.||.| 
yednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeks
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_4.PD 237-324 36 3.9e-20 63.6 In-house 166-249 (264) Show / Hide 
Range on Protein: 237-324
Range on HMM: 166-249/264
Sequence Identity: 36% (31 aa)

LQFTSWPDHGVPEQTKPMLDFVKNVREHIRKkcviKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
.|.. |.|.  |....|.... | |... ..    ||.||||||||||| |.. .|  |... .|  ..|  .| |.|  |||..   
vqvdwwrdqvaPldaapviklykavkkkkke----kPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqsh
Phosphatase Spur_PTPRB1.AA Subfamily.R_Nematode_2.PD 231-324 34 1.4e-19 61.7 In-house 159-246 (261) Show / Hide 
Range on Protein: 231-324
Range on HMM: 159-246/261
Sequence Identity: 34% (32 aa)

KREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHirkkcvIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTE
| |  .|...|||.|||.  . . . .. |..        ||.|||||||.|||...|. . |....| .. . .   . |.|||   .|||  
trtvthyqyeeWpdrgvPkshaelfeLlelvkks------ekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqte
Phosphatase Spur_PTPRB1.AA Subfamily.N23.PD 152-231 40 1.5e-19 61.6 In-house 109-190 (350) Show / Hide 
Range on Protein: 152-231
Range on HMM: 109-190/350
Sequence Identity: 40% (34 aa)

TIQAKYEHSRVKLM-ALKGKSETDYINANYIPGFN--SPrEYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
| . . ...||||  . . ... ||||| |.      || ..|| |||...| .| | |.||..| .|||.|. |||.| |..
tpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsP-pfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcd
Phosphatase Spur_PTPRB1.AA Subfamily.N20.PD 232-325 40 2.2e-19 61.3 In-house 154-243 (257) Show / Hide 
Range on Protein: 232-325
Range on HMM: 154-243/257
Sequence Identity: 40% (38 aa)

REVIQLQFTSWPDHGVPEQTKpmlDFVKNVReHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEV
. | ||||| ||||| |  .     |.| .| . ||  .  |.|||||||.|||| ....| .   .  |  ...  .|..|| .|. .|||. 
hsvkqlqftkwpdhgtpasad---sfikyir-yarkshltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtke
Phosphatase Spur_PTPRB1.AA Subfamily.N1.PD 156-229 39 2.5e-19 61.1 In-house 39-108 (268) Show / Hide 
Range on Protein: 156-229
Range on HMM: 39-108/268
Sequence Identity: 39% (29 aa)

KYEHSRVKLMalkgKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNK
|.|||.||     ....|||||. .   .  |.||  |||||.|..  |.|.||..|  ..|. . || ...| 
pydhsrikle----radvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqik
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_6.PD 236-325 40 2.6e-19 61.0 In-house 156-239 (253) Show / Hide 
Range on Protein: 236-325
Range on HMM: 156-239/253
Sequence Identity: 40% (35 aa)

QLQFTSWPDHGVPEQTKPMLDFVKNVREHirKkcviKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQTEV
... .|||||||.. .  | ... |...  |    ||.||||||||||||| . .  . . .   || .|  ..  .|  ||||||    
hihWanWPdhGvPdsflsalrllsvvkkd--k----kPivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtev
Phosphatase Spur_PTPRB1.AA Subfamily.N1.PD 229-324 38 6e-19 59.8 In-house 155-253 (268) Show / Hide 
Range on Protein: 229-324
Range on HMM: 155-253/268
Sequence Identity: 38% (37 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDF---VDVCGVVCEMRMHRNYLVQTE
.  ||... ..| ||| ||||  . .|.|. .|||    .  . |.|.|||||.||.||.  .| .  ..|...    ||.  |..|.| .||.||   
qetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtp
Phosphatase Spur_PTPRB1.AA Subfamily.R_Nematode_3.PD 229-325 30 6.5e-18 56.3 In-house 162-253 (267) Show / Hide 
Range on Protein: 229-325
Range on HMM: 162-253/267
Sequence Identity: 30% (30 aa)

KMKREVIQLQFTSWPDHGVPEQTKPMLDFVKNVRehirkKCViKPVVVHCSAGVGRTGTYIALDRLTQHMEDND-FVDVCGVVCEMRMHRNYLVQTEV
| .  |  |....|.....||..|..|. .|.|.     |.  .|||||||.|..|..|  | .   | .  ..  .|.  ...|.| .|   .||| 
kkeftvthllykgWkelnapeepkealelikfve-----ksk-tpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtel
Phosphatase Spur_PTPRB1.AA Subfamily.RN.PD 156-232 44 3.5e-17 53.8 In-house 38-115 (264) Show / Hide 
Range on Protein: 156-232
Range on HMM: 38-115/264
Sequence Identity: 44% (35 aa)

KYEHSRVKLMALKGKSETDYINANYIPGfNSPRE--YIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMKR
|.|||||| .   ....|||||  |   . ||.  |||.||||..|  |.|.|.||. ...||..|.  | | ...|| 
pydhsrvklkeeasaeksdyinasaild-hdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckr
Phosphatase Spur_PTPRB1.AA Subfamily.N_Fungi_PTP1.PD 157-231 39 4.2e-16 50.1 In-house 57-145 (343) Show / Hide 
Range on Protein: 157-231
Range on HMM: 57-145/343
Sequence Identity: 39% (34 aa)

YEHSRVKLM-AL-------KGKSETDYINANYIP------GFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
||||||||  .|       .  |  |||||||.         |.   ||| |.|||.| .|....| . | ..|...|. || ..|.  
YehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_egg.PD 158-225 41 2.9e-15 47.7 In-house 39-106 (257) Show / Hide 
Range on Protein: 158-225
Range on HMM: 39-106/257
Sequence Identity: 41% (28 aa)

EHSRVKLMALKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEG
| |||||   .|.   |.| ||.. |     |.| .| || .| .|.|||....|   |||.| ..| 
essrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_1.PD 158-230 37 1.2e-14 45.5 In-house 39-109 (265) Show / Hide 
Range on Protein: 158-230
Range on HMM: 39-109/265
Sequence Identity: 37% (27 aa)

EHSRVKLMalKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKM
...||||   .. . .||| |||.     |. .| .|.|| .|..|.| |.  .|   |||. ...| || | 
dknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkc
Phosphatase Spur_PTPRB1.AA Subfamily.R_Nematode_2.PD 172-231 40 1.2e-14 45.6 In-house 54-112 (261) Show / Hide 
Range on Protein: 172-231
Range on HMM: 54-112/261
Sequence Identity: 40% (24 aa)

ETDyINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMK
.. | ||..|  . |. .|| |||| .|..| | |.  .|   |||..|.||  |.| . 
rvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekce
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_4.PD 166-232 35 1.6e-14 45.2 In-house 44-110 (264) Show / Hide 
Range on Protein: 166-232
Range on HMM: 44-110/264
Sequence Identity: 35% (24 aa)

ALKGK-SETDYINANYIPGFnSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKMKR
|| .  . ||| |...       .||..||||.|| .|.| |... | ...||. . .|.| .| .| 
vlknrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcar
Phosphatase Spur_PTPRB1.AA Subfamily.N20.PD 157-229 48 8.7e-14 43.0 In-house 38-107 (257) Show / Hide 
Range on Protein: 157-229
Range on HMM: 38-107/257
Sequence Identity: 48% (36 aa)

YEHSRVKLmalkGKSEtDYINANYIPGFNSPREY--IACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNK
|. .|| |    |||. |||||.||   |   ||  || ||||  | .|.|.|. |..| .| |.|. .|||  |
ydstrvpl----gksk-dyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiik
Phosphatase Spur_PTPRB1.AA Subfamily.N_Fungi_PTP1.PD 233-300 37 1.4e-12 38.6 In-house 214-289 (343) Show / Hide 
Range on Protein: 233-300
Range on HMM: 214-289/343
Sequence Identity: 37% (29 aa)

EVIQLQFTSWPDHGV---PEQTKPMLDfV------KNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMED
|| |||.  |.| ..   ||.  ..|. |      ... |   ..   .|..||||||||||||...|| | ...|.
evyqlqvknWkDlslllnPesilqale-vkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfei
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_5.PD 157-224 30 5.8e-12 36.7 In-house 37-100 (258) Show / Hide 
Range on Protein: 157-224
Range on HMM: 37-100/258
Sequence Identity: 30% (21 aa)

YEHSRVklmaLKGKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVE
....||     ... . .||||..|   .. ...|  | |||.|..|.|||. ..| | .|..... |
lDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedee
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_5.PD 239-323 23 1.3e-11 35.5 In-house 159-242 (258) Show / Hide 
Range on Protein: 239-323
Range on HMM: 159-242/258
Sequence Identity: 23% (20 aa)

FTSWPDHGVPEQTKPMLDfvKNVREHIRKKCVI-KPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVCGVVCEMRMHRNYLVQT
.| |... ||...|...     . . ..|| .  .||||....|.||.|| ..|.   . ....  .... .. ..|  |   |..
lttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgaves
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_6.PD 171-230 39 1e-10 32.8 In-house 46-105 (253) Show / Hide 
Range on Protein: 171-230
Range on HMM: 46-105/253
Sequence Identity: 39% (23 aa)

SETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNKM
|  || ||..     || .| .|.|| .| ...|.||  . .. |||. . || ||.|  
dedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeks
Phosphatase Spur_PTPRB1.AA Family.DSP.PD 212-290 28 5.8e-10 30.3 In-house 132-204 (387) Show / Hide 
Range on Protein: 212-290
Range on HMM: 132-204/387
Sequence Identity: 28% (23 aa)

KSTIIVMMTqtvEGGKNKMKREVIQLQFTSWPDHGVPEQTKpMldFVKNVReHIRKK--CvIKPVVVHCSAGVGRTGTYIA
. | || .|   .. .. .|.. |.    ...||..|   . .  |.| ..  | ..  .  . |.||| ||.||.|| |.
gvtkivnlt---ddkpqftkelgikylripidDhnapplen-l--fekaid-fieegnds-kgvVlVHCkaGkgRsgtlii
Phosphatase Spur_PTPRB1.AA Subfamily.R_Nematode_3.PD 158-227 26 2e-09 28.5 In-house 36-114 (267) Show / Hide 
Range on Protein: 158-227
Range on HMM: 36-114/267
Sequence Identity: 26% (21 aa)

EHSRVKLMALKGKSETDYINANYIPgFNSPREYIACQGPL--------PETTNDMWRMIWEKKSTIIVMMTQTVE--GGK
|..||.|   . . . |.|.||..  ...  . |  |.|.         .| .  | || ..|....||. . ||  |..
ektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgee
Phosphatase Spur_PTPRB1.AA Subfamily.PTPDC1.PD 230-290 34 4.4e-09 27.4 In-house 131-185 (229) Show / Hide 
Range on Protein: 230-290
Range on HMM: 131-185/229
Sequence Identity: 34% (21 aa)

MKREVIQLQFtSWPDHGVPEQTKpMLDFVKNVREHIrKKCvikPVVVHCSAGVGRTGTYIA
|.....  .| ...|.||.  .. .|| || |   . ..     . ||| || ||||  ||
mrqgiyfynf-glkDygvasler-iLdivkvvdfal-eeg---kiavHCHAGlGRtGvlia
Phosphatase Spur_PTPRB1.AA Subfamily.TPIP.PD 243-289 39 3.7e-07 21.3 In-house 11-55 (245) Show / Hide 
Range on Protein: 243-289
Range on HMM: 11-55/245
Sequence Identity: 39% (18 aa)

PDHGVPEQtKPMLDFVKNVREHIRKKcVIKPVVVHCSAGVGRTGTYI
|| ||.  . .. | |.|.|.. |    . |..||  | ||||| . 
ddhnvPtl-eelvvftkevkewlakd-lenvvaihckGGkgrtGtiv
Phosphatase Spur_PTPRB1.AA Subfamily.PTEN.PD 211-290 25 5.4e-07 20.6 In-house 40-113 (305) Show / Hide 
Range on Protein: 211-290
Range on HMM: 40-113/305
Sequence Identity: 25% (20 aa)

KKSTIIVMMtQTVEGGKNKMKREVIQLQFTswpDHGVPeQTKPMLDFVKNVREHIRKKCvIKPVVVHCSAGVGRTGTYIA
.|  . ..     |  .....  |..  |.   ||  | . . . ..|..| ... .    . |.||| || ||||. |.
gkgklriln-argekedsdfdgrvavypfd---Dhnpp-tleLleeivedvdkwLkedk-snVvavHCkaGkGRtGvmic
Phosphatase Spur_PTPRB1.AA Subfamily.PRL.PD 196-306 24 7.4e-07 20.4 In-house 9-116 (140) Show / Hide 
Range on Protein: 196-306
Range on HMM: 9-116/140
Sequence Identity: 24% (26 aa)

PLPETTNDMWRMIwEKKSTIIVMMTQTVEGGKNKMKREVIQLQFTSWPDHGVPEQtKPMLDFVKNVREHIRKKcVIKPVVVHCSAGVGRTGTYIALDRLT
|  || ... ... .|.. . |. .  ..   .|.|.| |...  .. | .|| . . . .... ..|. ...   . | ||| ||.||..||  . . |
psdetvekfieel-kkenvkevvrvcepsydaeklkeegievldlafddGavPpk-evvdeWlellkekfkee-pkstvavhcvaGlGraPvlvalalie

QHMEDNDFVDV
. .| |..   
aGmkyedavef
Phosphatase Spur_PTPRB1.AA Subfamily.DSP11.PD 214-289 29 3.9e-06 18.1 In-house 23-99 (141) Show / Hide 
Range on Protein: 214-289
Range on HMM: 23-99/141
Sequence Identity: 29% (23 aa)

TIIVMMTQTVEGG-KNKMKREVIQLQFTSWPDHGVPEQTKpMLDFVKNVREHIR-KKCVIKPVVVHCSAGVGRTGTYI
... .|.|     |.... | .. .    | | |||. . . .| ..|.|..  .|   | . |||  || |||  | 
GLvidltntdryykkkeltdegvkykklncpGhevpeked-vkkfkeavkefleknkdndkligvhCthGvnrtGyli
Phosphatase Spur_PTPRB1.AA Subfamily.DSP23.PD 221-291 31 4.7e-06 18.0 In-house 20-86 (128) Show / Hide 
Range on Protein: 221-291
Range on HMM: 20-86/128
Sequence Identity: 31% (22 aa)

QTVEGGKNKMKREVIQLQFTSWPDHGVPeQTKPMLDFVKNVREHIRKKcviKPVVVHCSAGVGRTGTYIAL
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lttegapyseaapsltlrridipdfcPP-aleqvarlvriveeaekke---eavgvhcalGlGrtGtllac
Phosphatase Spur_PTPRB1.AA Subfamily.N_Nematode_eak.PD 158-229 26 7.2e-06 16.8 In-house 39-109 (281) Show / Hide 
Range on Protein: 158-229
Range on HMM: 39-109/281
Sequence Identity: 26% (19 aa)

EHSRVKLMALKgKSETDYINANYIPGFNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTQTVEGGKNK
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drylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveeklek
Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPRB1.AA Protein None 756 None Fasta, JSON
Spur_PTPRB1.NA RNA None 2268 None Fasta, JSON
Spur_PTPRB1.AA.PD_109-345 Protein Phosphatase Domain None 237 None Fasta, JSON